The production of adhesions between the parietal and visceral pleura. The procedure is used in the treatment of bronchopleural fistulas, malignant pleural effusions, and pneumothorax and often involves instillation of chemicals or other agents into the pleural space causing, in effect, a pleuritis that seals the air leak. (From Fishman, Pulmonary Diseases, 2d ed, p2233 & Dorland, 27th ed)
Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)
An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL.
An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.
Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms.
Paired but separate cavity within the THORACIC CAVITY. It consists of the space between the parietal and visceral PLEURA and normally contains a capillary layer of serous fluid that lubricates the pleural surfaces.
Endoscopic examination, therapy or surgery of the pleural cavity.
Catheters designed to be left within an organ or passage for an extended period of time.
Protective places of employment for disabled persons which provide training and employment on a temporary or permanent basis.
A live, attenuated varicella virus vaccine used for immunization against chickenpox. It is recommended for children between the ages of 12 months and 13 years.
Books designed to give factual information or instructions.
Surgery performed on the thoracic organs, most commonly the lungs and the heart.
The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.
A slightly movable cartilaginous joint which occurs between the pubic bones.
Chemical agents injected into blood vessels and lymphatic sinuses to shrink or cause localized THROMBOSIS; FIBROSIS, and obliteration of the vessels. This treatment is applied in a number of conditions such as VARICOSE VEINS; HEMORRHOIDS; GASTRIC VARICES; ESOPHAGEAL VARICES; PEPTIC ULCER HEMORRHAGE.
A collection of watery fluid in the pleural cavity. (Dorland, 27th ed)

Effectiveness of silver nitrate compared to talc slurry as pleural sclerosing agent in rabbits. Influence of concomitant intrapleural lidocaine. (1/130)

The ideal agent for producing pleurodesis has not been identified. Talc, the most commonly used, poses several problems. Another possibility is silver nitrate, which was widely used in the past. PURPOSE: To determine the influence of the intrapleural instillation of lidocaine in producing a pleurodesis with silver nitrate, to define the effect of lidocaine in the maturation of the collagen fibers, and to confirm that the pleurodesis after silver nitrate is stronger than after talc. METHODS: We studied three groups of 8 rabbits. Two groups received 0.5% silver nitrate; in one we had previously injected 0.5 ml of 2% lidocaine. The third group received 400 mg/kg talc (2 ml). The animals were sacrificed 28 days after the injection, and the pleural spaces were assessed grossly for evidence of pleurodesis and microscopically for evidence of inflammation and fibrosis. The total amount of pleural collagen and the distribution of thick and thin collagen fibers were quantified. Collagen was identified using picrosirius red stain. RESULTS: In the two groups that received silver nitrate (without lidocaine: 3.5 + 03 and with lidocaine: 3.2 + 0.3), the macroscopic pleurodesis (scale 0 - 4) was significantly (p = 0.001) better than that resulting from talc (1.6 + 0.2). The mean degree of pleural fibrosis induced by silver nitrate (3.5 + 0.2) was significantly (p = 0.004) higher than that induced by talc (1.9 + 0.1). The previous instillation of lidocaine resulted in a tendency for decreased amounts of fibrosis (3.1 + 0.4). The mean amount (10(3)mm2) of pleural collagen was significantly (p = 0.009) greater in the rabbits that received silver nitrate (116.9 + 22.7) than in those that received talc (10.7 + 3.4). The injection of lidocaine slightly reduced the collagen (80.1 + 30.3). The distribution of collagen fibers did not differ among the groups. CONCLUSION: This rabbit model clearly confirms that intrapleural silver nitrate is more effective than talc for producing pleurodesis. The previous intrapleural instillation of lidocaine results in a decreasing trend in the amount of collagen, but does not change the effectiveness of the pleural fusion or modify the process of collagen maturation.  (+info)

Pulmonary lymphangiomyomatosis (LAM) developing chylothorax. (2/130)

We describe a case of pulmonary lymphangiomyomatosis (LAM) with chylothorax that developed in a 46-year-old Japanese woman. This patient exhibited clinical symptoms of dyspnea and chest X-ray showed right pleural effusion. Thoracocentesis demonstrated chylous effusion. Chest computed tomography (CT) scan revealed multiple cystic lesions. Subsequent thoracoscopy revealed the chylorrhea from swelled vessels on the diaphragm. The clinical diagnosis, based on histological examinations with biopsy specimens obtained by thoracoscopy, was pulmonary LAM. Although the hormone therapy was not effective, chylous effusion was improved by the pleurodesis. Pulmonary LAM developing chylothorax is rare in Japan.  (+info)

Video assisted thoracoscopic bullectomy and acromycin pleurodesis: an effective treatment for spontaneous pneumothorax. (3/130)

The introduction of video assisted thoracoscopic surgery (VATS) has led to the development of several endoscopic options for the management of spontaneous pneumothorax. We describe here our experience in the management of primary spontaneous pneumothorax (SP). We carried out 58 VATS procedures on 55 patients during the period 1993-95. There were six conversions to open thoracotomy because of dense adhesions in five patients and a large apical bulla of 20 cm in one. These patients were excluded from the study. The remaining 49 patients underwent 52 VATS procedures. There were 37 males and 12 females with a median age of 23 (range: 15-71) years. The indications for surgery were persistent SP for more than 5 days in 21 (40%), and recurrent SP in 31 (60%). Twenty-six procedures (25 patients) consisted of bullectomy alone (group 1; 1/1/93-30/9/94) and the next 26 procedures (24 patients) included chemical pleurodesis with 2 g of Acromycin (Lederle) in 10 ml of 0.9 normal saline (group 2; 1/10/94-31/12/95). Both groups had a mean follow up of 38 months (range: 36-40). Mean postoperative chest drainage in group 2 (3.1 +/- 1.09) was significantly shorter than in group 1 (4.7 +/- 1.0). Group 2 patients also had a shorter hospital stay (4.8 /- 1.08 vs. 6.76 +/- 1.09). There were five (20%) recurrences in group 1 while only one (4%) occurred in group 2. In view of these results we recommend the routine use of Acromycin pleurodesis in addition to thoracoscopic bullectomy.  (+info)

Transforming growth factor beta(2) (TGF beta(2)) produces effective pleurodesis in sheep with no systemic complications. (4/130)

BACKGROUND: We have recently shown that transforming growth factor (TGF)beta(2) induces effective pleurodesis in rabbits. However, rabbits have a thin pleura while humans have a thick visceral pleura. The effect of intrapleural administration of TGF beta(2) in animals with a thick pleura and its associated systemic effects have not been investigated. This study was undertaken (1) to develop a new animal model for the study of pleurodesis using sheep which have a thick pleura resembling that of humans; (2) to study the efficacy of TGF beta(2) as a pleurodesis agent in the sheep model; and (3) to assess whether histological changes occur in extrapulmonary organs after intrapleural administration of TGF beta(2). METHODS: Twelve sheep were divided into four groups and were given a single intrapleural injection of TGF beta(2) in a concentration of 1.0 microg/kg, 0.5 microg/kg, 0.25 microg/kg or 0.125 microg/kg to the right pleural cavity via a chest tube. The left pleural cavity served as the control. Any pleural fluid that accumulated after the intrapleural TGF beta(2) injection was collected and analysed. The degree of pleurodesis was graded from 1 (no adhesions) to 8 (complete symphysis >50% of chest wall) at day 14 when the sheep were killed. Biopsy specimens were taken from the lungs and extrapulmonary organs. RESULTS: All sheep that received > or = 0.25 microg/kg TGF beta(2) developed excellent pleurodesis (score = 8) while those that received 0.125 microg/kg had a median score of 6. The pleurodesis score did not exceed 2 in the control (left) side of any sheep. Sheep receiving > or = 0.50 microg/kg TGF beta(2) developed large exudative pleural effusions while those receiving a lower dose did not. The production of effusions neither hindered nor was necessary for inducing pleurodesis. There were no significant fibrotic changes in any of the extrapulmonary organs. CONCLUSION: Intrapleural injection of 0.25-1.0 microg/kg TGF beta(2) produces excellent pleurodesis in a new sheep model with no evidence of extrapulmonary fibrosis.  (+info)

Comparison of the effectiveness of some pleural sclerosing agents used for control of effusions in malignant pleural mesothelioma: a review of 117 cases. (5/130)

BACKGROUND AND OBJECTIVES: Management of malignant pleural mesothelioma (MPM) has been an important clinical issue regardless of the treatment modality employed. We aimed to investigate the efficacy of oxytetracycline (OT), Corynebacterium parvum (CP), and nitrogen mustard (NM) in the management of pleural effusion associated with MPM. METHODS: One hundred and seventeen patients who had stage-2 MPM or over according to the Butchart staging system and unilateral or bilateral pleural effusion took part in the study. The patients received either OT (35 mg/kg), CP (7 mg), or NM (0.4 mg/kg) through a chest tube for pleurodesis. The association between several clinical parameters and patient survival was also investigated. RESULTS: OT was applied to 59, CP to 29 and NM to 29 cases. A statistical analysis of the results obtained by these agents have demonstrated that OT (30 days, 81%; 90 days, 76.2%) and CP (30 days, 86.2%; 90 days, 79.3%) led to a significantly higher rate of successful pleurodesis as compared to NM (30 days, 48.2%; 90 days, 41.3%; p <0.05). Although the procedure was generally well tolerated by the patients, the NM-treated group experienced significantly more nausea-vomiting (46.1%) and hypotension (35.8%) compared to patients who received OT (nausea-vomiting and hypotension 4.3%; p < 0.001) and CP (nausea-vomiting and hypotension 5.1%; p < 0.001). Furthermore, we found that thrombocytosis, chest pain and weight loss were significantly associated with poor prognosis, whereas epithelial type had a positive effect on survival. CONCLUSION: These results suggest that OT and CP may be used as effective sclerosing agents for pleurodesis in the control of pleural effusions associated with MPM, without major side effects.  (+info)

Radicular involvement and medullary invasion from a malignant mesothelioma. (6/130)

We present the case of a 57-year-old patient who had worked at a fiber-cement factory for 28 years. The patient developed an epithelioid-type pleural mesothelioma 5 years after retiring, after he was diagnosed with asbestosis. Only 5 months after the diagnosis of mesothelioma, a medullar section appeared to be totally invaded by a tumor in the medullar canal, thus causing paraplegia and affecting the bladder and anal sphincters. The patient underwent radiotherapy and chemotherapy, and achieved partial recovery, but died 9 months after the diagnosis.  (+info)

Transforming growth factor beta2 induced pleurodesis is not inhibited by corticosteroids. (7/130)

BACKGROUND: Talc and tetracyclines induce pleurodesis by directly injuring the pleura. The injury results in intense inflammation which subsequently leads to fibrosis. Corticosteroids can inhibit talc pleurodesis by reducing the inflammatory process. We hypothesised that transforming growth factor beta2 (TGFbeta2), a fibrogenic cytokine with immunomodulatory functions, could induce effective pleurodesis without generating significant pleural inflammation and therefore remain effective despite co-administration of corticosteroids. METHODS: Thirty rabbits were divided into two groups. Rabbits in the steroid group received weekly intramuscular injections of triamcinolone diacetate (0.8 mg/kg). Ten rabbits in each group were given 5.0 microg TGFbeta2 intrapleurally via a chest tube while the remaining five received 1.7 microg TGFbeta2. Pleurodesis was graded macroscopically after 14 days from 1 (none) to 8 (>50% symphysis). RESULTS: TGFbeta2 produced excellent pleurodesis at both 5.0 microg and 1.7 microg doses. The pleural effusions produced after the injection were low in all inflammatory markers. No significant differences were seen between the steroid group and controls in macroscopic pleurodesis scores (7.2 (1.3) v 7.1 (1.2)), levels of inflammatory markers in the pleural fluids (leucocyte 1107 (387)/mm(3) v 1376 (581)/mm(3); protein 3.1 (0.3) mg/dl v 2.9 (0.3) mg/dl, and LDH 478 (232) IU/l v 502 (123) IU/l), and the degree of microscopic pleural fibrosis and pleural inflammation. CONCLUSIONS: TGFbeta2 can induce effective pleurodesis and remains effective in the presence of high dose parenteral corticosteroids.  (+info)

Factors related to pleural effusions after Fontan procedure in the era of fenestration. (8/130)

BACKGROUND: Significant pleural effusions after the Fontan operation prolong hospital stay, may increase the risk of infection, and may necessitate a pleurodesis procedure. METHODS AND RESULTS: From February 1991 to April 2000, 98 consecutive patients under the age of 18 years underwent the fenestrated Fontan procedure at Children's Hospital of Wisconsin. Ninety-four patients who survived at least 30 days after surgery were retrospectively evaluated for the following factors: age, ventricular morphology (right single ventricle, left single ventricle [RV/LV]), fenestration open (FO) or closed (FC) at end of operation, intracardiac Fontan (IF) or extracardiac Fontan (EF), days with chest tube output per day >5, 10, and/or 20 mL. kg(-1). d(-1) (CTO5, CTO10, and CTO20, respectively), need for pleurodesis, length of hospital stay (LOS), operation during winter respiratory viral season of November through March (ReVS+, ReVS-), and pre-Fontan mean pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). In univariate analysis, the ReVS+ patients had prolonged LOS, greater chest tube output, and more pleurodesis (P<0.05), and PAP was related to CTO5 and CTO10 but not to CTO20 or LOS. No significant differences were found in LOS, CTO5, CTO10, CTO20, and need for pleurodesis between patients in RV/LV, FO/FC, IF/EF, or PVR groups. Patients <4 years of age had more instances of CTO20 (P<0.05). When we used ordinary least squares regression analysis with age, FO or FC, RV or LV, PAP, and ReVS+ or ReVS- to predict each of CTO5, CTO10, CTO20, and LOS, only ReVS+ or ReVS- and age were statistically significant in all models. CONCLUSIONS: Use of the Fontan procedure during the respiratory viral season appeared to be related to significant, prolonged pleural effusions and longer hospitalizations.  (+info)

In this largest study of pleurodesis outcomes in patients with MPM, 42% of patients underwent pleurodesis. Pleurodesis success rates were suboptimal: ,30% of patients achieved complete lifelong control of their effusion and 32% required further pleural drainages. Surgical pleurodesis provided no advantages over bedside pleurodesis in success rate, survival or duration of hospitalisation. None of the clinical, biochemical or radiological parameters studied adequately predicted pleurodesis failure. These results provide, for the first time, MPM-specific data to inform clinicians/patients on the efficacy of pleurodesis and may influence clinical care.. MPM remains incurable and symptom palliation for breathlessness is paramount. Conventional teaching suggests that malignant effusions should be drained and pleurodesis considered in symptomatic patients. However, MPM differs from metastatic pleural carcinomas in their pathobiology, which may explain the lower success rate of pleurodesis.1 First, ...
Background: Chemical pleurodesis is the treatment of choice in most cases of malignant pleural effusion. The literature mentions a variety of chemicals which may be used for this purpose, each with its own advantages and disadvantages. The iodopovidone has been recently studied due to the existence of some side effects of other agents. Nevertheless, there are still some questions in the literature regarding its safety and possible adverse effects. Because of these questions, we propose the development of a study to ensure the safety and efficacy of iodopovidone as a pleurodesis sclerosing agent.. Objective: The main purpose of this study is to evaluate the safety of pleurodesis for malignant pleural effusion using iodopovidone as a sclerosing agent in different doses. The secondary objectives are to determine clinical efficacy and quality of life of the patients after realization of the proposed procedure.. Methods: There will be a randomized clinical trial, covering patients diagnosed with ...
Background: As pleurodesis causes systemic inflammation and is associated with considerable cost and morbidity during long-term follow up, the identification of patients who will experience an unsuccessful pleurodesis would be desirable. This study was aimed to investigate whether systemic inflammatory reaction induced by insuflation of talc into the pleura can predict the outcome of pleurodesis.. Methods: A total of 58 consecutive patients (26 men, 32 women) with malignant pleural mesothelioma underwent video-assisted thoracoscopy under general anaesthesia with monopulmonary ventilation between the years 2003 and 2006. Four grammes of asbestos-free and sterile talc were insuflated into the pleural space under direct vision. To assess the success of pleurodesis, chest radiographs were obtained at the 8th and 30th postoperative days. Venous blood samples were drawn both on admission and at the 24th hour after pleurodesis for the analysis of white blood cells, erythrocyte sedimentation rate and ...
Surgical pleurodesis may be performed via thoracotomy or thoracoscopy. This involves mechanically irritating the parietal pleura, often with a rough pad. Moreover, surgical removal of parietal pleura is an effective way of achieving stable pleurodesis. Alternatively, tunneled pleural catheters (TPCs) may be placed in an outpatient setting and often result in auto-pleurodesis, whereby portable vacuum bottles are used to evacuate the pleural fluid. Routine evacuation keeps the pleura together, resulting in physical agitation by the catheter, which slowly causes the pleura to scar together. This method, though the minimally invasive and minimal cost solution, takes an average of about 30 days to achieve pleurodesis and is therefore the slowest means of achieving pleurodesis among other modalities.[7] Sterile talc powder, administered intrapleurally via a chest tube, is indicated as a sclerosing agent to decrease the recurrence of malignant pleural effusions in symptomatic patients. It is usually ...
Thoracoscopic collagen pleurodesis in the treatment of malignant pleural effusions. Akopov, Andrei L.; Egorov, Vladimir I.; Varlamov, Vladimir V.; Levashev, Yuri N.; Artioukh, Dmitri Y. // European Journal of Cardio-Thoracic Surgery;Nov2005, Vol. 28 Issue 5, p750 Abstract: Objective: Pleurodesis is of a potential benefit in pleural carcinomatosis and symptomatic malignant effusions, but the best way of achieving this is still uncertain. The aim of this prospective study was to analyse the results of pleurodesis after intra-pleural thoracoscopic... ...
Chest drainage and pleurodesis have been the mainstays of treatment of malignant effusions for many years. Fluid is drained using an intercostal chest tube, and after complete drainage, a pleurodesis agent is instilled into the pleural cavity via the chest tube in an attempt to seal the pleural cavity and prevent fluid reaccumulation. This technique allows the lung to re-expand and relieves breathlessness and if pleurodesis is successful, it can provide long-term relief of symptoms. However, pleurodesis is not universally successful, with success rates in clinical trials ranging from 70-90 percent. The rate of successful pleurodesis in routine practice is perceived to be at the lower end of this estimate.. Parietal and visceral pleura apposition is essential for pleurodesis to be effective, so if the lung cannot fully expand to fill the chest cavity (i.e. if it is trapped) because of a visceral pleural peel: or endobronchial obstruction, pleurodesis will be ineffective. A low pleural fluid pH ...
If the doctor believes that a patient does not fall into the high risk category, pleurodesis may be performed outside an operating room during hospitalization. A sedative and general anesthetic will be given to the patient and a chest tube will be inserted to drain any existing fluid. Depending on the extent of the fluid, this process may take a few days. When all the fluid is removed, the talc or doxycycline will be inserted through the chest tube and clamped to avoid leakage. A suction device is then used to bring the two lung surfaces together. The biggest disadvantage of a non-surgical pleurodesis is that the chest tube may be in place for several days, which is quite uncomfortable, prompting the need for painkillers ...
Pleural effusion is a frequent manifestation, in part because of the increase in the incidence of cancer and, mainly, because of the survival of patients with malignant neoplasms.1,2 Since the presence of pleural effusion is indicative of disseminated disease and limited survival, the main objective of treatment is to offer a better quality of life to the patients, relieving symptoms basically characterized by dyspnea and pain.2 In addition, since systemic treatment frequently does not control the disease, the local approach to pleural effusion (in addition to drainage of the cavity for immediate improvement of manifestations) is the control of recurrence by sclerosis and symphysis of the pleural membranes, a process called pleurodesis.. The first reports on pleurodesis date back to the beginning of the 20th century,3 and although more than 100 years have passed since then and different agents have been employed, the search for the ideal sclerosing agent continues.4 Some antibiotics have ...
Swiss doctors have created a new tool for predicting mesothelioma outcomes with FDG-PET scans. FDG-PET scanning is a nuclear imaging technique. It gives doctors a non-invasive way to track the growth of pleural mesothelioma tumors. The Swiss team analyzed multiple PET scans and CT scans from mesothelioma patients. They used a computer to look for commonalities in the scans. Then they used the information to create a computer model for predicting mesothelioma outcomes with FDG-PET. The model may help doctors and patients make better decisions about mesothelioma treatment in the future. Imaging Studies for Mesothelioma Prognosis Pleural mesothelioma tumors occur on the pleural lining around the lungs. In the early stages, mesothelioma causes few symptoms. As mesothelioma tumors grow, they … Continue reading Predicting Mesothelioma Outcomes with FDG-PET: A New Model » ...
Pleurodesis can stop pleural effusion (buildup of fluid in the lungs) and relieve symptoms. Learn more about this surgical treatment option for mesothelioma.
Talc pleurodesis is the most effective treatment für malignant pleural effusions. It is a palliative procedure. The appearance of a malignant pleural effusions marks the beginning of the last part of life of a patient with cancer. The cardinal symptom is dyspnoea. To allay, we offer surgical pleurodesis, offen in blind action. This is causing high mortality. We performed 115 thoracoscopic talc pudrages between 1997 and 1999 (36 month). The inpatient mortality was 7,8%. The most offen origins of metastatic carcinoma were Breast cancer (MS 12,4 month), Lung cancer (MS 6,2 month), Carcinoma of unknown primary (MS 10,7 month), Malignant mesothelioma (MS 10,9 month) and Ovarian cancer (MS 2,2 month). The patients with Breast-, Lung- and Ovarian cancer suffered the must from dyspnoea after pleurodesis. Thats why it is necessary, to find standards to choose suitable patients, which profit. In literature there are definite connection between Karnofsky Performance Scale of a patient, pleural fluid pH ( ...
Dyspnea is the main reason to treat a pleural effusion. There are different ways to treat a malignant pleural effusion. • Drain the fluid by inserting a needle into the pleural sac. Pleural fluid tends to reaccumulate, which may make it necessary to repeat the drainage process. • Pleurodesis involves draining the pleural fluid and placing a substance (a sclerosing agent) in the pleural space to create irritation. The irritation causes the two sides of the pleural sac to stick together leaving no room for reaccumulation of fluid. Pleurodesis can be done two different ways. The chest tube method involves inserting a tube through the chest wall into the pleural space. The tube is attached to a suction device that gently draws out the pleural fluid. Once the fluid has been drained and a local painkiller has been administered, a sclerosing agent is injected into the pleural space. Alternatively, pleurodesis can be performed through an endoscope, which allows the surgeon to see the pleural space. ...
In pleurodesis,​ an irritant (such as Bleomycin, [[Tetracyclines]],​ or talc powder) is instilled inside the space between the pleura (the two layers of [[tissue]] lining the lungs) in order to create inflammation which tacks the two pleura together. This procedure thereby obliterates the space between the pleura and prevents the reaccumulation of fluid ...
URN zum Zitieren dieses Dokuments: urn:nbn:de:bvb:355-epub-208148. Segerer, Hugo, Richter, K. und Scheele, J. (1984) Fibrinpleurodese eines beidseitigen Spannungspneumothorax bei Mukoviszidose = Fibrin pleurodesis of bilateral tension pneumothorax in mucoviscidosis. Klinische Pädiatrie 196 (1), S. 44-46 ...
Hello,. Im not sure what exact details youre interested in stayingcalm so Ill provide my moms experiences from her pleurodesis on. Oh, my mother has never been put on Alitma. Reinstones1s mother had background in both. You may want to search for her posts instead. With my mom, her pleurodesis was performed at the hospital where talc was inserted between the lung linings. During her hospital stay to recover and get to the point where she wasnt still excreting as much fluids, the nurse practioner had to inject more talc into the linings because they suspected the first pleurodesis procedure didnt take. She was in the hospital for 8 days and started chemo in less than a week. Keep in mind the talc is meant to irritate the lungs so it does cause a lot of coughing. It took a long time for the drainage incision to heal completely (about 3 months) so fluids were still leaking from it. During that time, she didnt have any difficulty in breathing. But when the incision healed, the fluids began to ...
Occurs in approximately 3 percent of cases, but its onset is usually delayed. Treatment follows the usual principles of empyema care, including hospitalization, intravenous antibiotics tailored to culture results (with staph. Aureus being the most common), continuous drainage of the pleural space via the intrapleural catheter, and use of CT imaging to define the fluid collection. Loculated effusion can be treated with intrapleural thrombolytics/DNAse and/or placement of additional pleural drains. The intrapleural catheter can be removed once adequate pleural drainage has been achieved, preferably prior to discontinuation of antibiotics. Surgical drainage is rarely considered or required.. In empyema in the setting of trapped lung, complete drainage and sterilization of the pleural space may be challenging. Surgical decortication could be considered in patients with very good performance status, but in most cases chronic drainage of the effusion is performed with the intrapleural catheter and ...
The goal of this clinical research study is to compare 2 different methods for treating a pleural effusion. Researchers also want to learn how the trea
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As with any cancer, treatment for Mesothelioma depends on the location of the cancer, the progression of the disease, the age as well as state of health of the patient.. It is the oncologist who specializes in the disease who will decide on the line of treatment. The disease is difficult to treat and in most cases the prognosis is poor. Treatment options include:. 1. If the diagnosis is done in the early stages surgery may be recommended to remove all cancerous tissues. This means thoracoscopy, VATS or video assisted thoracic surgery, mediastinoscopy (used for staging), or laproscopy. Often, doctors will advise palliative procedures like chest tube drainage and pleurodesis, thoracoscopy and pleurodesis, pleuroperitonial shunt, or pleurectomy, which treat the symptoms of mesothelioma rather than the disease.. 2. Radiation is prescribed aggressively for mesothelioma patients and is often given in combination with surgery or in order to control symptoms, palliatively. Research on using radiation ...
As with any cancer, treatment for Mesothelioma depends on the location of the cancer, the progression of the disease, the age as well as state of health of the patient.. It is the oncologist who specializes in the disease who will decide on the line of treatment. The disease is difficult to treat and in most cases the prognosis is poor. Treatment options include:. 1. If the diagnosis is done in the early stages surgery may be recommended to remove all cancerous tissues. This means thoracoscopy, VATS or video assisted thoracic surgery, mediastinoscopy (used for staging), or laproscopy. Often, doctors will advise palliative procedures like chest tube drainage and pleurodesis, thoracoscopy and pleurodesis, pleuroperitonial shunt, or pleurectomy, which treat the symptoms of mesothelioma rather than the disease.. 2. Radiation is prescribed aggressively for mesothelioma patients and is often given in combination with surgery or in order to control symptoms, palliatively. Research on using radiation ...
the past, some health facilities in Brazil utilized oral tetracycline/doxycycline derivatives to induce interleukin 2-alpha, staphylococcal superantigen pleurodesis. Nevertheless, there are doubts as to and TGF-β. In a comparative, randomized, whether the sclerosing effect observed is due to prospective, parallel study carried out in 2004, IFN- the agent used or to the excipient (talc). In a 2b was found to be less efficacious than addition, we should also be concerned with the bleomycin,(17) and its use was not indicated for sterilization of the agent introduced in the pleural pleurodesis induction. Staphylococcal superantigen cavity, since the capsules are in fact commercially seems to be a promising agent, despite having been distributed for oral ingestion and their content is little studied. In a study carried out in 2004,(18) not sterile and are therefore not recommended for staphylococcal superantigen was instilled in fourteen patients with low performance status Silver nitrate was the ...
A localized pleurodesis for lung devices created utilizing a combination of a mechanical component and a chemical component. The chemical component is utilized to create an acute adhesion between the
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Hello friends,My mom, (aged 77, Adenocarcinoma NSCLC, Stage 4, EGFR and ALK negative)  was diagnosed in 2014, underwent VATS and pleurodesis, followed by 6 cycles of Carboplatin & Alimta, Alimta maintenance, Tarceva (for just a couple of months) and is now on Keytruda for her stage 4, lung cancer treatment.  Her PDL-1 expression was over 70%.The
Question - Pluerodesis done on left side due to Spontaneous Heamothorax. Scan report showed large pluera but no malignancy. Surgery?. Ask a Doctor about Pleurodesis, Ask a Pulmonologist
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The purpose of this study is to analyze and compare radiological lung expansion after talc pleurodesis performed either by videothoracoscopy or chest tu
Talc pleurodesis is an effective technique for the management of symptomatic malignant pleural effusions. It is assumed that a good dispersion of talc suspension contributes to the final success of this treatment. For this purpose, guidelines often advise to rotate the patient after intra-pleural in …
Abstract. Purpose: Talc pleurodesis (TP) is employed worldwide for the management of persistent pneumothorax or pleural effusion, particularly of malignant origin. However, there are very little available data on 18F-fluorodeoxyglucose positron-emission tomography/computed tomography (18F FDG PET/CT) response evaluation in malignant pleural mesothelioma (MPM) patients treated with TP and chemotherapy.. Methods: Patients with histologically confirmed MPM underwent TP and FDG PET/CT staging and restaging after 3-4 courses of chemotherapy. All patients fasted and received a dose of 5.18 MBq 18F-FDG per kilogram of body weight. Whole-body emission scans were acquired with and without Ordered Subset Expectation Maximization (OSEM) iterative reconstruction algorithm.. Results: From January 2004 to March 2010, 8 patients with biopsy confirmed MPM (7 epithelial, 1 biphasic), with a median age of 65 years (range: 54-77), were evaluated. Median follow-up was 31 months (range: 4-44). After TP treatment, ...
The estimated recurrence rate of primary spontaneous pneumothorax is 23-50% after the first episode, and the optimal treatment remains unknown. In the recently published British Thoracic Society (BTS) guidelines, simple aspiration is recommended as first line treatment for all primary pneumothoraces requiring intervention. However, the 1 year recurrence rate of this procedure was as high as 25-30%, making it inappropriate as a standard of care.. Intrapleural instillation of a chemical irritant (chemical pleurodesis) is an effective way to shorten the duration of air leaks and reduce the rates of recurrent spontaneous pneumothorax in surgical and non-surgical patients. Many chemical irritants (tetracycline, talc, and minocycline) have been used to decrease the rate of recurrence in spontaneous pneumothorax. Tetracycline, which was the most commonly used irritant, is no longer available. Talc insufflation of the pleural cavity is safe and effective for primary spontaneous pneumothorax. However, it ...
Pleural fluid and trapped lung. Pleural effusions usually recur after drainage, so definitive management is required either with talc pleurodesis or an indwelling pleural catheter (IPC).2. In the former, talc is introduced into the pleural space following thoracoscopy or via chest drain. This procedure is successful in around 70% of cases. Talc pleurodesis can be painful, so adequate analgesia is required.9 IPCs enable pleural fluid to be drained regularly at home, providing symptom control. More than 95% of patients with an IPC achieve symptomatic improvement, with less than 10% having complications which necessitate removal of the IPC.10. IPCs are also recommended for management of a trapped lung. This occurs when pleural infiltration prevents lung re-expansion following drainage of pleural fluid, meaning talc pleurodesis is unlikely to succeed due to reduced parietal and visceral pleural contact (see figure 2).11. Surgery. Studies have shown increased length of hospital stay and complication ...
RESULTS: For conventional VATS talc pleurodesis the Mean Survival Time was estimated at 8.170 months with SEM 1.305. Median Survival Time was estimated at 4.133 months with standard error of Mean (SEM) of 0.731. For single-port VATS talc pleurodesis Mean Survival Time was estimated at 14.849 months with SEM of 4.965. Median Survival Time was estimated at 2.900 months with standard error of 0.907 ...
Normally, the lung is covered in a thin film of tissue, as is the inner lining of the rib cage and chest wall, and these two films are stuck together. However, sometimes air, fluid or both gets between these layers, separating them and limiting the ability of the lung to expand during breathing. When excess fluid develops between these layers, this is called pleural effusion. Pleurodesis is a technique to make these two layers stick together.. ...
Lenvatinib, a novel potent multikinase inhibitor, was approved for the treatment of radioiodine-refractory differentiated thyroid cancer based on results from phase III trial (SELECT study). Thyroid cancer is a diverse disease that includes anaplastic thyroid cancer (ATC), which the most aggressive form of the disease, although it accounts for ,2% of all thyroid cancers. Current treatments for ATC have limited efficacy. We report the case of a woman with recurrent well-differentiated papillary carcinoma of the thyroid that had transformed into ATC who developed a perforation of the small intestine secondary to a marked effect of lenvatinib ...
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BACKGROUND and OBJECTIVE:. Searching for the ideal pleurodesis agent still continues, Bleomycin is one of the most commonly used agents for pleurodesis. Tranexamic acid have been reported as a cheap pleurodesis agent by many authors. In this study, we evaluate the efficacy, safety and cost of using a combination of bleomycin and Tranexamic acid versus each agent alone.. METHODS:. Sixty three patients with massive malignant pleural effusions were divided in 3 equal groups in a simple randomized manner. Tranexamic acid (30 mg/kg [maximum of 2 g] in 50 mL of normal saline) was administered through a chest tube in Group 1. Group 2 received bleomycin (1 U/kg [maximum of 60 U] in 70 mL of normal saline). Group 3 received the above 2 preparations (tranexamic acid, 30 mg/kg [maximum of 2 g] in 40 mL of normal saline and bleomycin, 1 U/kg [maximum of 60 U] in 50 mL of normal saline) instilled one following the other by 15 minutes. Follow-up CXR examinations were performed at 7 days, 30 days, 60 days and ...
Also called Spontaneous pneumothorax, is a collection of air or gas in the chest that causes the lung to collapse. Spontaneous means there is no traumatic injury to the chest or lung. Causes, incidence, and risk factors There are two types of spontaneous pneumothorax: Primary spontaneous pneumothorax Secondary spontaneous pneumothorax Primary spontaneous pneumothorax occurs in people without lung disease. It usually occurs in tall, thin men between the ages of 20 and 40. Usually, the rupture of a small air- or fluid-filled sac in the lung (called a bulla) causes a primary spontaneous pneumothorax. Secondary spontaneous pneumothorax most often occurs with chronic obstructive pulmonary disease (COPD). Other lung diseases commonly associated with spontaneous pneumothorax include: Tuberculosis Pneumonia Asthma Cystic fibrosis Lung cancer Interstitial lung disease ...
Importance: Spontaneous pneumothorax is a common disease known to have an unusual epidemiological profile, but there are limited contemporary population-based data. Objective: To estimate the incidence of hospital admissions for spontaneous pneumothorax, its recurrence and trends over time using large, longstanding hospitalization data sets in England. Design, Setting, and Participants: A population-based epidemiological study was conducted using an English national data set and an English regional data set, each spanning 1968 to 2016, and including 170 929 hospital admission records of patients 15 years and older. Final date of the study period was December 31, 2016. Exposures: Calendar year (for incidence) and readmission to hospital for spontaneous pneumothorax (for recurrence). Main Outcomes and Measures: Primary outcomes were rates of hospital admissions for spontaneous pneumothorax and recurrence, defined as a subsequent hospital readmission with spontaneous pneumothorax. Record-linkage was used
Title:Spontaneous Pneumothorax. VOLUME: 8 ISSUE: 4. Author(s):Nicole K. Jackson and Brian E. Louie. Affiliation:Swedish Cancer Institute and Medical Center, Suite 850, 1101 Madison Street, Seattle, WA 98104, USA.. Keywords:Pleurodesis, pneumothorax, secondary, spontaneous, thoracoscopy, VATS, epidemiology, pathophysiology, pleural space, emphysema.. Abstract:The management of spontaneous pneumothorax in the non-ventilated patient is determined by whether or not there is marked underlying lung pathology (secondary) or not (primary). Primary pneumothorax is generally managed initially by simple tube drainage, although the success of operative approaches suggests that earlier intervention may be beneficial. In contrast, patients with severe underlying lung disease have both increased operative risk, as well as failure of both operative and non-operative management. In either setting, early surgical consultation is ideal and particularly in the setting of secondary pneumothorax a multi-modality ...
Background Pneumothorax is a potentially life-threatening complication of chronic obstructive pulmonary disease (COPD) that leads to cardiopulmonary compromise. According to the British Thoracic...
Background Pleural disease affects 1 in 300 people annually; furthermore, the incidence of malignant pleural effusion (MPE) is increasing with over 40,000 cases each year in the UK alone. A significant minority of patients will have non-expandable lung (NEL) secondary to underlying disease. At present, there is no way of pre-emptively identifying these individuals; with current strategies such as pleural manometry requiring invasive intervention. Early recognition of patients with NEL would streamline care and allow them to be offered appropriate treatment; i.e., indwelling pleural catheter insertion rather than chemical pleurodesis. Recent research1 has described the novel use of thoracic ultrasound (TUS) to identify NEL by assessing mobility and compliance of the atelectatic lung within an effusion. However, this work has not been replicated and was delivered by researchers with expertise and facilities not used by or available to most practitioners. ...
Introducción. El objetivo de este estudio es comparar la efectividad y los posibles efectos secundarios de diferentes dosis del agente pleurodésico sericina.. Métodos. Se utilizaron ratas macho albinas Wistar de 12 meses de edad (n=52) que se dividieron aleatoriamente en 4 grupos, referidos como A, B, C y D. Se administró sericina a diferentes dosis a través de toracotomía izquierda: 15mg al grupo A, 30mg al grupo B y 45mg al grupo C. El grupo D se utilizó como grupo control. Las ratas se sacrificaron 12 días más tarde. Se realizó examen patológico del hemitórax izquierdo, el hígado y el riñón.. Resultados. No se observaron reacciones a cuerpo extraño en el parénquima de ninguna de las ratas. El enfisema fue menos común en el grupo B (p,0,05). El mesotelio multicapa en ambas pleuras fue más frecuente en el grupo B, mientras que la fibrosis y la organización de la fibrina en la pleura visceral tuvieron una mayor tasa de éxito en todos los grupos tratados con sericina que en ...
TY - JOUR. T1 - The Undefined Value of Pleural Interventions in Advanced Heart Failure and Recurrent Pleural Effusions. AU - Gilbert, Christopher R.. AU - Yarmus, Lonny. AU - Feller-Kopman, David. AU - Lee, Hans J. AU - Gorden, Jed A.. PY - 2016/3/1. Y1 - 2016/3/1. UR - http://www.scopus.com/inward/record.url?scp=84983226706&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84983226706&partnerID=8YFLogxK. U2 - 10.1513/AnnalsATS.201512-825LE. DO - 10.1513/AnnalsATS.201512-825LE. M3 - Letter. C2 - 26963358. AN - SCOPUS:84983226706. VL - 13. SP - 447. EP - 448. JO - Annals of the American Thoracic Society. JF - Annals of the American Thoracic Society. SN - 2325-6621. IS - 3. ER - ...
We unreservedly kamagra oral jelly uk next day delivery will minimise this potential bias by recruiting participants through searching general practice records and referral logs from primary care to local depression and anxiety treatment services, rather than by direct referral from general practitioners (GPs).. It will not cure heart failure but will help to control it.. 1 It is widely prescribed in low doses for management of sleep disorders, compazine for anxiety despite lacking approval for this use.! Paraurti di antibiotico combinazione per segni e.? Ovo je pogotovo bitno za napade koji su uvek iznova vraćaju.! Pleurodesis in patients with malignant pleural effusions: talc slurry or bleomycin?! Les sujets sous Niagra X ont connu un haut niveau d intensité sexuelle pour une durée allant jusquà 24 heures.! Porcelain veneers offer the best esthetics while providing the most conservative option to mask those tetracycline-stained teeth.? For a teenage boy who eats frequently, this can be ...
Spontaneous occurring of air in the pleural space in patients with an underlying lung disease is known as secondary spontaneous pneumothorax (SSP). Read on to know more.
1.. Kashiwada T, Shimizu H, Arai Y, Horie Y, Mizoo A, Takizawa S.[A case of anaphylactic reaction after pleurodesis with OK-432]. Nihon Kokyuki Gakkai Zasshi 47: 965-8, No. 10, Oct 2009 - Japan ...
So Im minding my own business, a little bit of a sore back (I get a sore back a lot, so thought nothing of it), when I turn and feel the sore back shift around my lung to become a sore chest. Another turn sends it back again. I knew what it was immediately, the shifting is air, which should be inside my lung, but isnt. Mostly because my lung has collapsed--the titular spontaneous pneumothorax. Good times ...
Spontaneous pneumothorax is cause of life-threatening respiratory distress in pets. Surgical management is often needed to maximize a positive outcome.
The purpose of this observational study was to characterize the clinical course of newborn infants with spontaneous pneumothorax and to identify those infants who eventually required further interventions. We performed a retrospective review of newbo
Diagnosis:Spontaneous Pneumothorax Amount of estimate: $3844 Owner Contribution: $800 Fund raising goal: $3165 (4% has been added to help pay IMOMs busines...
The initial chest x-ray confirms a large pneumothorax. A seldinger-type drain has been inserted with partial lung re-expansion. Drainage of the pneumothorax continued and there was no complication. An underlying cause was not found. The young ch...
Pneumothorax in children is an unusual disorder that can be life-threatening. It may be idiopathic or associated with underlying pulmonary disease. The prognosis is usually good, although recurrence is frequent.Pneumothorax is defined as a collection
مقدمه:پنوموتوراکس یا تجمع هوا در فضای جنب یکی از مشکلات تنفسی است که می تواند بالقوه خطرناک باشد. پنوموتوراکس به طور کلی به دو نوع خودبخودی و اکتسابی تقسیم می شود که نوع خودبخودی نیز به دو دسته اولیه و ثانویه تقسیم می گردد. پنوموتوراکس خودبخودی اولیه اغلب در افرادی دیده می شود که سابقه ای از بیماری مشخص از نظر بالینی ندارند ولی اغلب مشاهدات مبین آن است که پاره شدن بلب های ساب پلورال(subpleural blebs) شایعترین علت ایجادکننده آن می باشد. روش کار:این مطالعه ابتدا با مراجعه به بخش بایگانی بیمارستان امام خمینی(ره) کلیه پرونده های مربوط به بیماران که از سالهای 1386- 1389با
Pleurodesis[edit]. It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, ... "Iodine pleurodesis--a word of caution". European Journal of Cardio-Thoracic Surgery. 41 (5): 1209. doi:10.1093/ejcts/ezr137 ... "Efficacy & safety of iodopovidone pleurodesis: a systematic review & meta-analysis". The Indian Journal of Medical Research ...
Pleurodesis is also ineffective. Urinothoraces typically resolve spontaneously without recurring after the underlying urinary ...
This is called pleurodesis. Pleurodesis involves the drainage of all the fluid out of the chest through a chest tube. A ...
Shaw, P; Agarwal, R (2004). Shaw, Paul HS (ed.). "Pleurodesis for malignant pleural effusions". The Cochrane Database of ...
Pleurodesis may also be helpful. Menstruation and accompanying lung collapse can be suppressed with hormone therapy, like with ...
Management of malignant pleural effusions by talc pleurodesis Sigmoid volvulus in pregnancy: case report and review of ... Waqainabete, Ifereimi (September 2006). "Management of malignant pleural effusions by talc pleurodesis". Pacific Health Dialog ...
... pleurodesis for recurrent pleural effusions or spontaneous pneumothorax; surgical stapler-assisted wedge resection of lung ... pleurodesis, and lung or pleural biopsies, while more technically demanding operations such as esophageal operations, ...
A low pleural fluid pH is associated with poorer survival and reduced pleurodesis efficacy. Pleural fluid cytology is positive ... Diagnostic significance and prognostic value in respect to pleurodesis". Am. Rev. Respir. Dis. 139 (3): 663-7. doi:10.1164/ ... Standard treatment involves inserting an indwelling plural catheter and pleurodesis. However, this treatment requires an ...
Results of chemical pleurodesis tend to be worse than when using surgical approaches, but talc pleurodesis has been found to ... Pleurodesis is a procedure that permanently eliminates the pleural space and attaches the lung to the chest wall. No long-term ... Those who have undergone pleurodesis may need two to three weeks off work to recover. Air travel is discouraged for up to seven ... If a chest tube is already in place, various agents may be instilled through the tube to achieve chemical pleurodesis, such as ...
Some of these people required thoracentesis or pleurodesis to treat the effusions. Other adverse events included mild to ...
Amin R, Noone PG, Ratjen F (December 2012). "Chemical pleurodesis versus surgical intervention for persistent and recurrent ...
It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is ... "A study of comparison of efficacy and safety of talc and povidone iodine for pleurodesis of malignant pleural effusions". ...
Mesothelial cells may also be decreased in cases of rheumatoid pleuritis or post-pleurodesis pleuritis. Eosinophils are often ...
... of those had had prior bilateral pleurodesis. Although pleurodesis is not a contraindication to transplantation, it can result ... Chemical pleurodesis is generally an effective therapy for chylothorax, as is mechanical abrasion and talc poudrage. Renal ... About half of LAM patients who have undergone transplant have had a prior pleurodesis procedure, and more than 75% ...
Sterile talc powder (NDC 63256-200-05) is a sclerosing agent used in the procedure of pleurodesis. This can be helpful as a ... In medicine, talc is used as a pleurodesis agent to prevent recurrent pleural effusion or pneumothorax. In the European Union, ...
For recurrent pleural effusions, pleurodesis can be performed to establish permanent obliteration of the pleural space. "pleura ...
Surgical treatments for symptoms of lymphangioleiomyomatosis (LAM) in adult TSC patients include pleurodesis to prevent ...
A procedure known as pleurodesis, which involves using substances such as talc to scar together the pleura, may be used to ...
A technique called pleurodesis can be used to intentionally create scar tissue within the pleural space, usually as a treatment ... Fibrosis in the pleura may be produced intentionally using a technique called pleurodesis to prevent recurrent punctured lung ( ...
Pleurodesis Ligation of thoracic duct Pleurperitoneal shunt Radiation therapy Pleurectomy Surgical resection Thalidomide ...
... sending him to the hospital and forcing him to undergo a medical procedure known as Pleurodesis. Just a few days after being ...
... pleurodesis, Blebectomy, pleurectomy, Thoracentesis), Thyroid bx, Thyroid nodule fna, Thyroidectomy, Vasectomy, Whipple ...
... pleurodesis - plexiform neurofibroma - plexopathy - ploidy - Plummer-Vinson syndrome - pluripotent - pluripotent stem cell - pM ...
Pleurodesis) Desis (spider), a genus of intertidal spiders Desi (disambiguation) This disambiguation page lists articles ...
... pleurodesis, ligation of thoracic duct, pleuroperitoneal shunt, radiation therapy, pleurectomy, pericardial window, ...
Injection into thoracic cavity Chemical pleurodesis (35) Operations on valves and septa of heart (35.0) Closed heart valvotomy ...
Surgical pleurodesis, also known as abrasive pleurodesis, may be performed via thoracotomy or thoracoscopy. This involves ... takes an average of about 30 days to achieve pleurodesis and is therefore the slowest means of achieving pleurodesis among ... Pleurodesis is a medical procedure in which part of the pleural space is artificially obliterated. It involves the adhesion of ... Chemical pleurodesis is a painful procedure, and so patients are often premedicated with a sedative and analgesics. A local ...
Shaw, P; Agarwal, R (2004). "Pleurodesis for malignant pleural effusions". The Cochrane database of systematic reviews (1): ...
"pleurodesis" at Dorlands Medical Dictionary *^ Chen MD, Chan MD, Tsai MD, Hsu MD, Lin MS, Yuan MD, Prof Chen MD, Prof Lai MD, ... takes an average of about 30 days to achieve pleurodesis and is therefore the slowest means of achieving pleurodesis among ... Pleurodesis is a medical procedure in which the pleural space is artificially obliterated.[1] It involves the adhesion of the ... Chemical pleurodesis is a painful procedure, and so patients are often premedicated with a sedative and analgesics. A local ...
Treatments and Tools for pleurodesis. Find pleurodesis information, treatments for pleurodesis and pleurodesis symptoms. ... pleurodesis - MedHelps pleurodesis Center for Information, Symptoms, Resources, ... Hello, I am a 24YO white male 66". About 5 years ago I had 2 Pleurodesis operations (mec... ... About 13 years ago I underwent a pleurodesis on my right lung after experiencing pleural ef... ...
... Chest. 1993 Dec;104(6):1763-6. doi: 10.1378/chest.104.6. ... Survival, duration of chest tube instillation, and success of pleurodesis assessed by radiographic pleural fluid reaccumulation ...
In this largest study of pleurodesis outcomes in patients with MPM, 42% of patients underwent pleurodesis. Pleurodesis success ... Patients who underwent pleurodesis spent more time in hospital than those in the non-pleurodesis group (median 20 days (IQR 12- ... Many believe that pleurodesis is more likely to be successful if performed early. In our study, surgical pleurodesis was often ... Pleurodesis outcome. Complete success was achieved in 29.7% and partial success in 38.8% of patients treated with pleurodesis. ...
Pleurodesis is used as a possible treatment for complications from lung cancer, but it may also be recommended for other health ... Chemical pleurodesis-The doctor makes a small incision in the chest and inserts a chest tube to remove any fluid from the ... Pleurodesis is used as a possible treatment for complications from lung cancer, but it may also be recommended for other health ... After pleurodesis, a patient may stay in the hospital overnight for observation. This is an important way to ensure recovery is ...
thoracoscopic pleurodesis who subsequently have either procedure performed. 2. Sufficient mental capacity to answer SF-6D and ... 1. Patients undergoing pleurodesis for benign disease (e.g., spontaneous pneumothorax). 2. Inability or unwillingness to give ... Comparative Effectiveness of Indwelling Pleural Catheters Versus Thoracoscopic Pleurodesis for Treatment of Malignant Pleural ... Comparative Effectiveness of Indwelling Pleural Catheters Versus Thoracoscopic Pleurodesis for Treatment of Malignant Pleural ...
... Respiration. 1988;53(3):197-200. doi: 10.1159/000195413 ... Chemical pleurodesis causes a significant reduction of the recurrence rate in the treatment of idiopathic SP. ... Patients in group 2B were treated by chemical pleurodesis with iodinated talcum. In only 1 did a recurrence occur. ... Complications of thoracoscopy and/or pleurodesis were not observed. We conclude that thoracoscopy enables accurate assessment ...
Pleurodesis (also known as pleural sclerosis) involves instilling an irritant into the pleural space to cause inflammatory ... How is pleurodesis (pleural sclerosis) used in the treatment of pleural effusions (fluid on the lungs)?. Updated: Dec 28, 2018 ... Pleurodesis is most often used for recurrent malignant effusions, such as in patients with lung cancer or metastatic breast or ... Pleurodesis for malignant pleural effusions: current controversies and variations in practices. Curr Opin Pulm Med. 2004 Jul. ...
Pleurodesis for malignant pleural effusion: talc, toxicity and where next? Davies, Helen E.; Lee, Y. C. Gary; Davies, Robert J ... Pleurodesis, from the Greek pleura and desis (binding together), is intended to achieve a symphysis between parietal and ... Long-term outcome of pleurodesis with OK-432 in metastatic breast cancer: a new risk model for success from an analysis of 75 ... Thoracoscopic collagen pleurodesis in the treatment of malignant pleural effusions. Akopov, Andrei L.; Egorov, Vladimir I.; ...
If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patients written consent to publication and send them to the editorial office before submitting your response [Patient consent forms] ...
Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax. The safety and ... Patients and Methods Study design This study is a randomized trial of additional minocycline pleurodesis after VATS for primary ... Postoperative care and minocycline pleurodesis The patients were extubated in the operating theater and observed for 1 to 2 ... To test if additional minocycline pleurodesis after thoracoscopic procedures can reduce the rates of ipsilateral recurrence for ...
Computed tomography appearances of talc pleurodesis are well described [8, 9]. Results of talc pleurodesis can be seen at CT ... Talc pleurodesis has proven its role in treatment of pneumothoraces [5]. There are no or minimal long-term side effects in ... H. Peek, W. van der Bruggen, and G. Limonard, "Pleural FDG uptake more than a decade after talc pleurodesis," Case Reports in ... J. G. Murray, E. F. Patz, J. J. Erasmus, and R. C. Gilkeson, "CT appearance of the pleural space after talc pleurodesis," ...
Scarification of pleura Pleurodesis, from the Greek pleura and desis(binding together), is the artificial production of ... 1995). Talc slurry pleurodesis. Pleural fluid and histologic analysis. Chest, 107(6), 1707-1712.CrossRefPubMedGoogle Scholar ... 2006). Experimental pleurodesis induced by antibiotics (Macrolides of quinolones). Clinics, 61(6), 559-564.CrossRefPubMedGoogle ... 2012). Pleurodesis outcome in malignant pleural mesothelioma. Thorax, 68(6), 594-596.CrossRefGoogle Scholar ...
Talc for pleurodesis? Chest. 2002;122:1506-8. [ Links ]. 19. Sahn SA. Talc should be used for pleurodesis: pro/con editorials. ... of pleurodesis in rabbits using talc commonly employed in pleurodesis (particles of @ 8.3 µm) and talc with particles of a ... in pleurodesis induced with small-particle talc. The final outcome of pleurodesis was the same after 3 months (85% success in ... Talc for pleurodesis: hero or villain? Chest. 2003;124:416. [ Links ]. 24. Van der Heuvel MM, Smith HJ, Barbierato SB, Havenith ...
Chemical pleurodesis produced a complete response in 752 (64%) of 1168 patients. The success rate of the pleurodesis agents ... malignant pleural effusions treated with chemical pleurodesis were selected and reviewed for pleurodesis regimen, number of ... To provide information about available agents for chemical pleurodesis.. Data Sources. A MEDLINE search (1966 to October 1992) ... Studies including a total of 1168 patients with malignant pleural effusions were reviewed for efficacy of the pleurodesis agent ...
Active Comparator: Talc Pleurodesis For patients in this group, chest tube type PIGTAIL 10 - 14 Fr will be inserted by by chest ... Management of Malignant Pleural Effusion - Indwelling Pleural Catheter or Talc Pleurodesis. The safety and scientific validity ... Procedure: Talc Pleurodesis chest tube type PIGTAIL 10 - 14 Fr will be inserted to the pleural space. In case of fluid ... Procedure: Talc Pleurodesis Procedure: Indwelling Pleural Catheter Procedure: chest ultrasound Drug: Local anesthesia Procedure ...
The purpose of this study is to analyze and compare radiological lung expansion after talc pleurodesis performed either by ... Talc pleurodesis is the most popular method to control symptoms of recurrent malignant. pleural effusion. The intrapleural talc ... obtained obtained in the first 7 days and 1, 3 and 6 months after pleurodesis. All. examinations were revised by two ... Analysis of Clinical and Radiological Results of Two Methods of Talc Pleurodesis in Patients With Recurrent Malignant Pleural ...
Chemical pleurodesis produced a complete response in 752 (64%) of 1168 patients. The success rate of the pleurodesis agents ... malignant pleural effusions treated with chemical pleurodesis were selected and reviewed for pleurodesis regimen, number of ... Thoracoscopic Talc Poudrage Pleurodesis for Chronic Recurrent Pleural Effusions Annals of Internal Medicine; 115 (10): 778-782 ... Chemical Pleurodesis for Malignant Pleural Effusions Pamela B. Walker-Renard, PharmD; Leigh M. Vaughan, PharmD; Steven A. Sahn ...
Pleurodesis following pleural aspiration decreases the chance of pleural effusion recurrence, and has been a widely used long- ... The aim of this study is to evaluate the effect of pleurodesis using ultrasound-guided iodopovidone sclerotherapy in hepatic ... Conclusion: Ultrasound-guided iodopovidone sclerotherapy is an effective approach for a successful pleurodesis in hepatic ... Pleurodesis following pleural aspiration decreases the chance of pleural effusion recurrence, and has been a widely used long- ...
Arm II (talc pleurodesis): Patients undergo talc pleurodesis via an indwelling intercostal chest drain or via thoracoscopy ... Talc pleurodesis may keep fluid from building up in the chest cavity. It is not yet known which therapy is more effective in ... Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma (MesoVATS). The safety and ... Patients undergo talc pleurodesis via an indwelling intercostal chest drain or via thoracoscopy either at the time of biopsy or ...
A Prospective Randomised Study of Efficacy, Safety and Costs of Talc Pleurodesis Under Medical Thoracoscopy and Pleurodesis ... But additional pleurodesis is potentially useless procedure on the parietal pleura for treating visceral pleural disese. ... Home » Topics » Anesthesiology » Research » Efficacy of the Additional Mechanical Pleurodesis for Surgical Management of ... According to our previous study, stapling resection of the bulla without pleurodesis gave comparable result in recurrence ...
Increased pleural fibrinolytic activity after talc pleurodesis has been reported to be associated with failure of pleurodesis ... coupled with talc pleurodesis. There were no episodes of acute respiratory failure following talc pleurodesis. A total of 56 ( ... Long-term follow-up of thoracoscopic talc pleurodesis for primary spontaneous pneumothorax. S. Györik, S. Erni, U. Studler, R. ... the use of talc as the sclerosant of choice and thoracoscopic pleurodesis as the preferred technique for pleurodesis based on ...
Bedside pleurodesis*Sclerosing agents for bedside pleurodesis*Thoracoscopy/talc poudrage*Outcomes*Pleurodesis rates*Symptom ... Bedside pleurodesis. Bedside pleurodesis can be performed on an inpatient basis in a regular medical or surgical ward. Small ... Pleurodesis rates following talc pleurodesis have been documented to be as high as 90 percent, but these results are not ... Pleurodesis rates. Pleurodesis has long been considered the primary endpoint for treatment of malignant pleural disease. A ...
Talc pleurodesis can function as a model of the human response to mineral oxide particle exposure, albeit a massive one. ... talc pleurodesis in humans alters iron homeostasis.In vitroexposures of both mesothelial and airway epithelial cells to 100 μg/ ...
Pleurodesis. Used to treat pleural mesothelioma, pleurodesis is a surgical procedure that introduces an irritant into the ... Pleurodesis is best utilized among mesothelioma patients decline other, more aggressive treatment options or who are not ... Generally used when the pleural effusion is symptomatic, pleurodesis is a treatment administered through a thoracoscopy or ...
Bedside pleurodesis. Bedside pleurodesis can be performed on an inpatient basis in a regular medical or surgical ward. Small ... Pleurodesis rates following talc pleurodesis have been documented to be as high as 90 percent, but these results are not ... Pleurodesis rates. Pleurodesis has long been considered the primary endpoint for treatment of malignant pleural disease. A ... Since pleurodesis rates cannot be easily compared between intrapleural catheters and chemical pleurodesis, the need for ...
Patients who had pleurodesis and completed the follow up: - Patients with bleomycin pleurodesis - Patients with iodine ... Thus, fifty one had pleurodesis and completed the follow up. Four weeks after pleurodesis, they had echography that was ... To prevent re-accumulation of pleural fluid we should try pleurodesis. Pleurodesis is the creation of fibrous adhesions between ... Among povidone-iodine group (n= 25) excellent pleurodesis (no. = 20), effective (n= 2) and weak pleurodesis (n= 3). The six ...
The outcome of talc pleurodesis in rabbits (talc slurry) is reported in Tables I and II; the outcome of talc pleurodesis in ... In conclusion, despite pleurodesis being one of the most requested procedures for the treatment of many systemic and thoracic ... Talc pleurodesis has been associated with pleuropulmonary damage, particularly long‑term damage due to its inert nature. The ... Sahn SA: Talc should be used for pleurodesis. Am J Respir Crit Care Med. 162:2023-2049. 2000. View Article : Google Scholar : ...
The procedure administered to achieve this goal is pleurodesis. Pleurodesis is the iatrogenic closure of the pleural cavity by ... In this study, pleurodesis was performed at an early stage in group I patients who had low amounts of pleural fluid, and at a ... In this study, pleurodesis was found to have a low rate of success and high probability of recurrence of effusion in late phase ... In this study, pleurodesis was performed in early stage cases, where the primary tumor type was known and there were no ...
  • Surgical pleurodesis may be performed via thoracotomy or thoracoscopy . (wikipedia.org)
  • in group 2 thoracoscopy was performed and in case of an idiopathic SP, pleurodesis was carried out with iodinated talcum. (nih.gov)
  • Complications of thoracoscopy and/or pleurodesis were not observed. (nih.gov)
  • Arm II (talc pleurodesis): Patients undergo talc pleurodesis via an indwelling intercostal chest drain or via thoracoscopy either at the time of biopsy or after confirmation of biopsy results. (clinicaltrials.gov)
  • A follow-up study was undertaken in all patients with primary spontaneous pneumothorax who underwent talc pleurodesis for prolonged air leak or recurrence using thoracoscopy. (ersjournals.com)
  • Talc pleurodesis in patients with primary spontaneous pneumothorax via thoracoscopy is an effective procedure associated with normal lung function in patients who do not smoke. (ersjournals.com)
  • Therapeutic options for treatment include placement of an indwelling pleural catheter and chemical pleurodesis via chest tube or thoracoscopy. (clinicaladvisor.com)
  • Generally used when the pleural effusion is symptomatic, pleurodesis is a treatment administered through a thoracoscopy or existing chest tube. (mesotheliomacenter.org)
  • Pleurectomy or pleural abrasion with chemical pleurodesis, thoracoscopy, and thoracotomy are all methods used to prevent recurrence of MPE [3]. (termedia.pl)
  • Of these, 37 (37.37%) patients underwent pleurectomy or pleural abrasion following recurrence, while in 62 (62.63%) cases, tube thoracostomy or thoracoscopy with pleurodesis was performed. (termedia.pl)
  • median age 67 years, range 47-82 years) with MPE related to different malignancies underwent video-assisted thoracoscopy talc pleurodesis. (iiarjournals.org)
  • Forty-six patients (median age 67 years, range 47-82 years) with MPE related to different malignancies underwent video-assisted thoracoscopy (VATS) and pleurodesis with large-particle (mean size 25 μm) talc (Steritalc, Novatech, France), administered by a pneumatic atomizer. (iiarjournals.org)
  • All symptomatic patients with malignant pleurisy subjected to talc pleurodesis through medical thoracoscopy between January 2012 and December 2015 were included. (readbyqxmd.com)
  • In cases with an established malignant diagnosis, medical thoracoscopy also has a therapeutic role in the form of pleurodesis. (medscape.com)
  • How is pleurodesis (pleural sclerosis) used in the treatment of pleural effusions (fluid on the lungs)? (medscape.com)
  • Pleurodesis is most often used for recurrent malignant effusions, such as in patients with lung cancer or metastatic breast or ovarian cancer. (medscape.com)
  • Thoracoscopic collagen pleurodesis in the treatment of malignant pleural effusions. (ebscohost.com)
  • Abstract: Objective: Pleurodesis is of a potential benefit in pleural carcinomatosis and symptomatic malignant effusions, but the best way of achieving this is still uncertain. (ebscohost.com)
  • Since the introduction of talc pleurodesis by Bethune in 1935, this procedure is used to manage recurrent malignant and nonmalignant pleural effusions and recurrent or persistent pneumothoraces [ 1 ]. (hindawi.com)
  • Chemical pleurodesis for malignant pleural effusions. (springer.com)
  • All articles containing references to patients with recurrent, symptomatic, malignant pleural effusions treated with chemical pleurodesis were selected and reviewed for pleurodesis regimen, number of patients treated, success rate (complete response), and adverse effects. (ovid.com)
  • Studies including a total of 1168 patients with malignant pleural effusions were reviewed for efficacy of the pleurodesis agent and studies including 1140 patients were reviewed for toxicity. (ovid.com)
  • Walker-Renard, P.B., Vaughan, L.M. and Sahn, S.A. (1994) Chemical pleurodesis for malignant pleural effusions. (scirp.org)
  • Effusions of malignant origin are the most common indication for pleurodesis Thoracic ultrasound (TUS) can easily visualize pleural effusions and help in identifying malignant effusion and the presence of pleural adhesions or thick pleural peel and could therefore have a role in predicting long-term pleurodesis success or failure in MPE. (clinicaltrials.gov)
  • A recent Cochrane review on pleurodesis for malignant pleural effusions has revealed that the available evidence supports the need for chemical sclerosants for successful pleurodesis, the use of talc as the sclerosant of choice and thoracoscopic pleurodesis as the preferred technique for pleurodesis based on efficacy 16 . (ersjournals.com)
  • The current Lancet presents an observational study of the safety of talc pleurodesis for malignant pleural effusions . (pallimed.org)
  • It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). (wikipedia.org)
  • There are numerous fixes for pleural effusions , but a pleurodesis is a potential permanent one. (mesotheliomaguide.com)
  • Fewer overall hospital days with use of indwelling pleural catheters vs pleurodesis for malignant effusions is a topic covered in the EE+ POEM Archive . (unboundmedicine.com)
  • Chemical pleurodesis is widely recommended in the treatment of pulmonary air leak of different etiologies as well as malignant pleural effusions and chylothorax. (biomedcentral.com)
  • Chemical pleurodesis is reported as the best treatment for recurrent pleural effusions when the underlying cause cannot be corrected. (springeropen.com)
  • Pleurodesis is performed to prevent recurrence of pneumothorax or recurrent pleural effusion . (wikipedia.org)
  • Pleurodesis is performed to prevent recurrence of spontaneous pneumothorax or pleural effusion, and can be done chemically or mechanically. (wikipedia.org)
  • Pleurodesis may be added to this procedure to reduce recurrence. (springer.com)
  • All cases with recurrence had undergone pleurodesis so it is difficult to prove its superiority. (springer.com)
  • Effectiveness of chemical pleurodesis in spontaneous pneumothorax recurrence prevention: a systematic review. (springer.com)
  • Chemical pleurodesis causes a significant reduction of the recurrence rate in the treatment of idiopathic SP. (nih.gov)
  • To test if additional minocycline pleurodesis after thoracoscopic procedures can reduce the rates of ipsilateral recurrence for patients with primary spontaneous pneumothorax. (clinicaltrials.gov)
  • 2 In addition, since systemic treatment frequently does not control the disease, the local approach to pleural effusion (in addition to drainage of the cavity for immediate improvement of manifestations) is the control of recurrence by sclerosis and symphysis of the pleural membranes, a process called pleurodesis. (scielo.br)
  • Management through complete drainage and instillation of a sclerosant to promote pleurodesis and prevent recurrence is usually effective. (ersjournals.com)
  • According to our previous study, stapling resection of the bulla without pleurodesis gave comparable result in recurrence comparing with articles with additional pleurodesis. (bioportfolio.com)
  • Most patients require definitive treatment, usually drainage and chemical pleurodesis to relieve symptoms and prevent fluid recurrence. (clinicaltrials.gov)
  • Chest X-ray proved recurrence of effusion in the six cases with weak pleurodesis after symptom-free intervals that varied between 4 and 6 weeks among these 6 patients. (omicsonline.org)
  • Cobanoglu U, Kemik O, Celik S, Sayir F. A novel approach for preventing recurrence of malign pleural effusion: early phase pleurodesis. (termedia.pl)
  • The success and recurrence rates were compared with regard to the two groups as well as method of pleurodesis, and mean survival was determined. (termedia.pl)
  • Among them, additional chemical pleurodesis was reported to be associated with the lowest recurrence rate during VATS bleb resection on the basis of the results of a recent meta-analysis ( 8 ). (amegroups.com)
  • Patients receiving TKIs had longest effusion-recurrence-free period of 352 days (close to a year) even without talc-pleurodesis, in comparison to patients with chemotherapy and best supportive care. (cdc.gov)
  • Pleurodesis is a medical procedure in which the pleural space is artificially obliterated. (wikipedia.org)
  • Chemical pleurodesis is a painful procedure, and so patients are often premedicated with a sedative and analgesics. (wikipedia.org)
  • Surgical pleurodesis showed no advantages over bedside pleurodesis in efficacy (32% vs 31% failures requiring further drainage, p=0.98), patient survival (p=0.52) or total time spent in hospital from procedure till death (p=0.36). (bmj.com)
  • Although pleurodesis is considered safe, there are always risks with any medical procedure. (cancercenter.com)
  • Nevertheless, pleural procedure after wedge resection such as pleurodesis has been performed in some patients who. (ebscohost.com)
  • But additional pleurodesis is potentially useless procedure on the parietal pleura for treating visceral pleural disese. (bioportfolio.com)
  • Used to treat pleural mesothelioma , pleurodesis is a surgical procedure that introduces an irritant into the pleural space that creates inflammation. (mesotheliomacenter.org)
  • The present model series review aimed to assess the safety of this procedure by examining inflammatory stimulus, biocompatibility and tissue reaction following talc pleurodesis. (spandidos-publications.com)
  • Clinical pleurodesis success was defined as no need for any other pleural procedure. (scielo.br)
  • Pleurodesis is a relatively safe procedure, although previous studies have described malignant invasion of scar tissue. (pubmedcentralcanada.ca)
  • Talc pleurodesis is recognized as the procedure of choice for the treatment of MPE [ 2 ], and a meta-analysis has confirmed the superiority of talc as a sclerosing agent [ 3 ]. (pubmedcentralcanada.ca)
  • A medical procedure routinely used for the treatment of recurrent pleural effusion (excess fluid that surrounds the lungs), pleurodesis is performed by the addition of a number of chemicals and agents into the pleural cavity, which first causes inflammation (pleuritis), and then causes the pleurae to stick together. (schmidtandclark.com)
  • Pleurodesis is often performed as an outpatient procedure, but this depends on the general health of the patient. (worthingtoncaron.com)
  • In particular cases of pleural effusion, your doctor may suggest pleurodesis, a procedure in which the two layers of the pleura are fused together. (mydr.com.au)
  • Talc pleurodesis is a low-invasive procedure and could improve the quality of life and survival time for late-stage pleural mesothelioma patients. (mesotheliomaguide.com)
  • Pleurodesis is a procedure where a mildly irritant drug is introduced into the space between the inner wall of the chest and the outer lining of the lung (pleural space). (melbourneheartsurgeon.com.au)
  • If it does, your doctor may require another pleurodesis procedure and it may not be as successful as the first. (melbourneheartsurgeon.com.au)
  • A pleurodesis procedure drains the fluid and goes a step further by also sealing the pleural space to prevent any further fluid buildup. (pleuralmesothelioma.com)
  • Pleurodesis is a surgical procedure that uses chemicals, talc or drugs to scar the space between the layers of the pleura. (survivingmesothelioma.com)
  • However, the researchers showed that a different procedure, one known as talc pleurodesis, can be significantly more effective. (prweb.com)
  • The talc pleurodesis procedure involves draining lung lining of fluid and then using talc to seal the pleural layers. (prweb.com)
  • Of those patients, 88 had the talc pleurodesis procedure and 87 had the VATPP procedure performed. (prweb.com)
  • According to the study, 24 of the VATPP patients suffered surgical complications, while complications occurred in only 10 of those patients who had the talc pleurodesis procedure performed. (prweb.com)
  • 52 percent of VATPP patients survived one year after the procedure while 57 of the talc pleurodesis patients had survived. (prweb.com)
  • 1 Talc pleurodesis induces an inflammatory response that leads to intensive proliferation of fibroblasts in the pleural surface within 3 days of the procedure and subsequently leads to pleural adhesions and a chronic granulomatous reaction. (ochsnerjournal.org)
  • Pleurodesis is a procedure used to help relieve some symptoms of malignant pleural Mesothelioma. (mesotheliomaclaimslawcenter.com)
  • If a Mesothelioma patients lung capacity is seriously reduced a Pleurodesis procedure may not help. (mesotheliomaclaimslawcenter.com)
  • There is still no way to predict how effective a Pleurodesis procedure will be in any individual Mesothelioma patient. (mesotheliomaclaimslawcenter.com)
  • This procedure is called pleurodesis. (medlineplus.gov)
  • Alayouty HD, Hasan TM, Alhadad ZA, Omar Barabba R. Mechanical versus chemical pleurodesis for management of primary spontaneous pneumothorax evaluated with thoracic echography. (springer.com)
  • Can chest ultrasonography assess pleurodesis after VATS for spontaneous pneumothorax? (ebscohost.com)
  • The Effect of Thoracoscopic Pleurodesis in Primary Spontaneous Pneumothorax: Apical Parietal Pleurectomy versus Pleural Abrasion. (ebscohost.com)
  • Background: The standard operative treatment of primary spontaneous pneumothorax (PSP) is thoracoscopic wedge resection, but necessity of pleurodesis still remains controversial. (ebscohost.com)
  • Aim To determine the efficiency and safety of talc pleurodesis in treating the malignant pleural effusion and recurrent spontaneous pneumothorax. (ebscohost.com)
  • Methods The study included 54 patients with malignant pleural effusion and recurrent spontaneous pneumothorax, who underwent talc pleurodesis using. (ebscohost.com)
  • Patients and Methods Study design This study is a randomized trial of additional minocycline pleurodesis after VATS for primary spontaneous pneumothorax. (clinicaltrials.gov)
  • After VATS for primary spontaneous pneumothorax, eligible patients were randomly assigned to additional minocycline pleurodesis or observation. (clinicaltrials.gov)
  • Optimal surgical management of primary spontaneous pneumothorax has been a matter of devate, especially regarding the method of pleurodesis. (bioportfolio.com)
  • The aim of the present study was to evaluate the long-term outcome of patients with primary spontaneous pneumothorax treated with talc pleurodesis. (ersjournals.com)
  • Thoracoscopic talc pleurodesis under local anaesthetic has been shown to be safe, cost-effective and superior to conservative treatment by chest tube drainage in primary spontaneous pneumothorax that fail simple aspiration 7 - 9 . (ersjournals.com)
  • 17 have reported mild restrictive impairment and pleural thickening following talc pleurodesis for primary spontaneous pneumothorax. (ersjournals.com)
  • The optimal chemical agent for additional pleurodesis during video-assisted thoracoscopic surgery (VATS) bleb resection in primary spontaneous pneumothorax (PSP) remains controversial. (amegroups.com)
  • Previous pneumothorax with or without pleurodesis is not a contraindication to subsequent lung transplantation. (wikipedia.org)
  • About 13 years ago I underwent a pleurodesis on my right lung after experiencing pleural ef. (medhelp.org)
  • Pleurodesis is used as a possible treatment for complications from lung cancer , but it may also be recommended for other health conditions that cause difficulty breathing. (cancercenter.com)
  • Lung expansion was evaluated through chest CT scans obtained obtained in the first 7 days and 1, 3 and 6 months after pleurodesis. (knowcancer.com)
  • A temporary increase in pain may be a sign of success when undergoing pleurodesis for mesothelioma-related lung fluid. (survivingmesothelioma.com)
  • Patients with successful talc pleurodesis had a median forced vital capacity (FVC) of 102% and median total lung capacity of 99% at follow-up. (ersjournals.com)
  • There are very limited data about the effects of talc pleurodesis on lung function 15 , 17 . (ersjournals.com)
  • Trapped lung - Incomplete re-expansion of the lung predicts failure of pleurodesis. (clinicaladvisor.com)
  • Finally, 54 patients had an evidence of possible lung expansion but three died before pleurodesis. (omicsonline.org)
  • Among bleomycin group (n = 26), echography showed excellent pleurodesis (n = 21), effective pleurodesis (n= 2) with one or two areas of free mobility and one area of fluid component, weak pleurodesis (no. = 3) with three areas of free lung movement (lung sliding sign) and areas of fluid component. (omicsonline.org)
  • To evaluate the role of intrapleural positioning of a pleural catheter in early lung expansion and pleurodesis success in patients with recurrent malignant pleural effusion (RMPE). (scielo.br)
  • We used the pleural volume on iCT scans to estimate early lung expansion and the difference between the pleural volumes on CT30 and iCT scans to evaluate radiological success of pleurodesis. (scielo.br)
  • Our results suggest that the position of the tip of the pleural catheter influences neither early lung expansion nor bedside pleurodesis success in patients with RMPE. (scielo.br)
  • A localized pleurodesis for lung devices created utilizing a combination of a mechanical component and a chemical component. (patents.com)
  • It should be taken into account that before performing pleurodesis, it is required to make total drainage and absolute re-expansion of the lung. (schmidtandclark.com)
  • If your lung capacity is already seriously diminished, pleurodesis may not work for you. (schmidtandclark.com)
  • The aim of TALC pleurodesis (injecting sclerosants such as TALC slurry into pleural space to adhere the linings of the lung together) is to reduce the chances of fluid re-accumulation. (ox.ac.uk)
  • Talc pleurodesis on lung and parietal pleura. (medscape.com)
  • 4. The method of claim 1 , wherein the therapeutic compound delivery system comprises a conduit and wherein step (b) comprises introducing the conduit through the chest wall through one of the one or more localized pleurodesis and into the lung alveolar tissue at the treatment site. (google.com)
  • 10. The method of claim 8 , wherein step (b) comprises creating a pleurodesis between the visceral membrane of the lung and the thoracic wall at the adhesion site. (google.com)
  • Meta-analyses demonstrated that the strongest predictors of pleurodesis success were higher pleural fluid pH, smaller volume of effusion pre-pleurodesis and full lung re-expansion post effusion drainage. (mesothelioma-line.com)
  • Conventional chemical pleurodesis using erythromycin, tetracycline, hydrophilic fumed silica, autologous blood and talc slurry has been standardized, and its complications, including high fever, intractable chest pain, and acute lung injury, seem to be frequent. (biomedcentral.com)
  • in this paper we report the first case of acute pneumonitis after pleurodesis using Viscum album extract in a 58-year-old man who had prolonged air leaks after a left upper lingularsegmentectomy for metastatic lung cancer. (biomedcentral.com)
  • In terms of treatment of lung cancer, among patients receiving talc pleurodesis, 14 received TKI`s, 2 received chemotherapy, and 11 received nil (best supportive care), as cancer specific therapy. (cdc.gov)
  • Ultrasound-guided iodopovidone sclerotherapy is an effective approach for a successful pleurodesis in hepatic hydrothorax. (scirp.org)
  • After successful pleurodesis for mesothelioma, there is no longer any space for fluid to collect. (survivingmesothelioma.com)
  • A total of 56 (95%) out of the cohort of 59 patients had a successful pleurodesis. (ersjournals.com)
  • Additionally, biomarkers of successful pleurodesis including measurement of pleural fluid proteins have not been validated in prospective studies. (readbyqxmd.com)
  • During his Academic Clinical Fellowship (ACF), Ahmed will be looking at ultrasound markers of successful pleurodesis in people with malignant pleural effusion. (ox.ac.uk)
  • Pleurodesis may prevent two conditions: pleural effusion and pneumothorax. (cancercenter.com)
  • Further medical history revealed a spontaneous left-sided pneumothorax, treated with talcage pleurodesis at the age of 20. (hindawi.com)
  • Pleurodesis, from the Greek pleura and desis (binding together), is the artificial production of adhesions between the parietal and visceral pleura for the treatment of a persistent pneumothorax or severe pleural effusion, and mesothelioma, according to the 29th edition of Dorland's Illustrated Medical Dictionary. (springer.com)
  • This sign of 'pleural sliding', firstly described in veterinary medicine and was used to exclude the presence of pneumothorax when present and to suspect atelectasis, fibrosis or pleural adhesions (pleurodesis) when absent. (clinicaltrials.gov)
  • According to the British Thoracic Society (BTS) guidelines, medical pleurodesis is recommended for inoperable patients suffering from COPD-related pneumothorax. (springer.com)
  • The aim of this study is to report our experience using PAMSHA in medical pleurodesis to treat inoperable cases of persistent pneumothorax secondary to COPD. (springer.com)
  • Records of 78 inoperable patients with persistent pneumothorax secondary to COPD treated with PAMSHA pleurodesis were retrospectively reviewed. (springer.com)
  • Our data suggest that PAMSHA pleurodesis is a safe and effective option for the treatment of persistent pneumothorax secondary to COPD. (springer.com)
  • To help shed more light on this matter, we present our study of the use of Pseudomonas aeruginosa-mannose-sensitive hemagglutinin (PAMSHA) for the pleurodesis of patients with pneumothorax secondary to COPD. (springer.com)
  • Talc pleurodesis (TP) is employed worldwide for the management of persistent pneumothorax or pleural effusion, particularly of malignant origin. (jcancer.org)
  • A bilateral recurrent tension pneumothorax in an 18-year-old patient with cystic fibrosis was treated by fibrin glue pleurodesis. (uni-regensburg.de)
  • Determining if the patient has a history of pneumothorax requiring talc pleurodesis and reviewing previous chest images are mandatory to avoid unnecessary invasive diagnostic procedures. (ochsnerjournal.org)
  • less than one month, The patients will be divided randomly for two groups, each group 60 patients, the first group will undergoes talc pleurodesis, the second group will undergoes Indwelling Pleural catheter insertion. (clinicaltrials.gov)
  • The patients underwent pleural catheter insertion followed by bedside pleurodesis. (scielo.br)
  • Spontaneous pleurodesis is another unique advantage of indwelling pleural catheter placement but the factors associated with its occurrence are not clearly established. (hkmj.org)
  • The aims of this study were to explore the safety of an indwelling pleural catheter in the management of symptomatic recurrent malignant pleural effusion, and to identify the factors associated with spontaneous pleurodesis. (hkmj.org)
  • Ten (43.5%) cases achieved minimal output according to defined criteria, in five of whom the pleural catheter was removed without subsequent re-accumulation of effusion (ie spontaneous pleurodesis). (hkmj.org)
  • Potential clinical factors associated with minimal output were identified along with the occurrence of spontaneous pleurodesis, which is a unique advantage offered by indwelling pleural catheter. (hkmj.org)
  • There are several options to treat MPE, including thoracentesis, placement of a long-term indwelling pleural catheter and chemical pleurodesis. (iiarjournals.org)
  • Pleurodesis generally requires you to stay in the hospital for a longer period but the doctor may recommend a small flexible tube (indwelling pleural catheter) to be surgically inserted in the chest where you can go home with it and be taught how to drain or a nurse will visit you at home to drain it themselves. (melbourneheartsurgeon.com.au)
  • Evaluation of efficacy (success rate), safety (side effects), and tolerability of tranexamic acid and iodopovidone as chemical agents for pleurodesis, in the management of recurrent pleural effusion using pigtail catheter. (springeropen.com)
  • The catheter was clamped for 6 h during which the patient was turned in all directions, supine, prone, right, left lateral decubitus, and sitting position so pleurodesis solution came in contact with all pleural surfaces [ 8 ]. (springeropen.com)
  • Alternatively, tunneled pleural catheters (TPCs) may be placed in an outpatient setting and often result in auto-pleurodesis, whereby portable vacuum bottles are used to evacuate the pleural fluid. (wikipedia.org)
  • Pleurodeses were defined as a complete success (no further fluid accumulation detected), a partial success (fluid returned but no further intervention required) or a failure (further fluid drainage needed) following the American Thoracic Society/European Respiratory Society consensus. (bmj.com)
  • Chemical pleurodesis-The doctor makes a small incision in the chest and inserts a chest tube to remove any fluid from the pleural cavity. (cancercenter.com)
  • Pleurodesis (sealing the pleural space) is done when fluid rapidly reaccumulates in the pleural space. (merckmanuals.com)
  • Pleurodesis, from the Greek pleura and desis (binding together), is intended to achieve a symphysis between parietal and visceral pleura, in order to prevent accumulation of either air (pneumothrax) or fluid (pleural effusion) in the pleural space. (ebscohost.com)
  • For patients in this group, chest tube type PIGTAIL 10 - 14 Fr will be inserted by by chest ultrasound guided and under local anesthesia, allowing good draining of the hemithorax, in case of fluid discharges less than 250 cc/24, talc pleurodesis will be performed, chest tube will be removed 24 - 48 hours later on. (clinicaltrials.gov)
  • the primary outcome was the measure of pleurodesis failure, defined as the reaccumulation of pleural fluid requiring further pleural intervention. (ersjournals.com)
  • Talc pleurodesis may keep fluid from building up in the chest cavity. (clinicaltrials.gov)
  • Thirty-five patients with MPE underwent VATS, evacuation of the pleural fluid and talc pleurodesis with large-particle talc. (sigmaaldrich.com)
  • In this study, pleurodesis was performed in early stage cases, where the primary tumor type was known and there were no symptoms related to the accumulation of pleural fluid, and in cases presenting with symptoms due to increased amounts of pleural fluid. (termedia.pl)
  • Pleurodesis is a mesothelioma treatment aimed at stopping fluid build-up in the lungs, therefore easing shortness of breath. (schmidtandclark.com)
  • Talc pleurodesis remains one of the most popular methods for fluid control. (readbyqxmd.com)
  • 20 were managed by pleural fluid drainage only whereas 14 underwent talc pleurodesis following pleural fluid drainage. (ntu.edu.sg)
  • Some patients who undergo pleurodesis have to be admitted to the hospital and remain overnight, especially if there is a lot of fluid. (worthingtoncaron.com)
  • It may be offered to people who repeatedly experience a build-up of fluid in the pleural cavity that makes it hard to breathe and who are unable to or prefer not to have pleurodesis. (cancercouncil.com.au)
  • Pleurodesis treatment helps prevents fluid buildup in the lungs and chest cavity. (mesotheliomaclaimslawcenter.com)
  • This fluid is removed through thoracentesis or pleurodesis . (mesothelioma.com)
  • Shorter duration of tube drainage, higher pleural fluid glucose, lower LDH and lower pleural tumour burden all seem to favour pleurodesis success, but with considerable statistical heterogeneity between studies. (mesothelioma-line.com)
  • Limited available data on possible long term complications associated with talc pleurodesis are available in the Literature ( 2 , 3 , 5 , 6 ). (spandidos-publications.com)
  • The perioperative outcomes, including fever, prolonged air-leak, prolonged-effusion, postoperative bed-side pleurodesis, and rehospitalization because of complications, were not significantly different between the two groups. (amegroups.com)
  • Since talc pleurodesis is far less invasive than EPP or P/D, there is often a greater chance of success and fewer complications associated with the operation. (mesotheliomaguide.com)
  • Survival, complications and response to pleurodesis were recorded. (biomedcentral.com)
  • Studies have found better success and less risk of patient complications when Pleurodesis is done Thoracoscopically. (mesotheliomaclaimslawcenter.com)
  • Moreover, the complications resulting from pleurodesis using Viscum album extract are very rare, and acute pneumonitis has not been reported. (biomedcentral.com)
  • Tranexamic acid and iodopovidone were found to be effective alternative agents for pleurodesis with low cost and minimal complications. (springeropen.com)
  • However, potentially harmful systemic side effects have been associated with talc pleurodesis. (scielo.br)
  • The aim of this study was to evaluate prognostic factors for survival of patients with symptomatic MPE who underwent palliative video-assisted thoracoscopic (VATS) talc pleurodesis. (sigmaaldrich.com)
  • We compared the efficacy and safety of iodopovidone with those of minocycline for additional chemical pleurodesis during VATS bleb resection. (amegroups.com)
  • or chemical, laser, or electrocautery pleurodesis with VATS bleb resection was attempted ( 7 ). (amegroups.com)
  • Surgical pleurodesis-The doctor makes a small incision and inserts medical talc into the space around the lungs using a thoracoscope, a hollow tube with a light and camera on the end. (cancercenter.com)
  • A total of 17 (13.28%) cases were patients who had undergone thoracotomy and/or thoracoscopic surgery via pleurectomy and/or decortication, it having been decided that chemical pleurodesis would not be effective due to expansion of the lungs. (termedia.pl)
  • To assess the success of pleurodesis, chest radiographs were obtained at the 8th and 30th postoperative days. (mesothelioma-line.com)
  • Serum levels of inflammatory parameters (C-reactive protein and erythrocyte sedimentation rate) may be used to predict the success of pleurodesis in patients with malign mesothelioma who underwent thoracoscopic talc poudrage. (mesothelioma-line.com)
  • Conclusions: Both bleomycin and povidone-iodine produced comparable excellent and effective pleurodesis among patients with malignant pleural effusion. (omicsonline.org)
  • We proposed that we may be able to replace bleomycin by the easily-available, less expensive and the less- toxic povidone-iodine for pleurodesis among patients with malignant pleural effusion in the course of bronchoginic carcinoma. (omicsonline.org)
  • Other limitations include non inclusion of additional procedures that may be added through the thoracoscopic approach and need for description of various other methods of pleurodesis available besides talc. (springer.com)
  • Studies on pleurodesis in MPM have been retrospective, underpowered and employed differing pleurodesis methods and definitions of success. (bmj.com)
  • Few data exist on the pleurodesis outcome in patients with malignant pleural mesothelioma (MPM). (bmj.com)
  • No clinical, biochemical or radiographic parameters tested adequately predict pleurodesis outcome. (bmj.com)
  • The primary outcome was success or failure of pleurodesis. (bmj.com)
  • Long-term outcome of pleurodesis with OK-432 in metastatic breast cancer: a new risk model for success from an analysis of 75 cases. (ebscohost.com)
  • Can serum inflammatory parameters estimate outcome of pleurodesis in mesothelioma? (mesothelioma-line.com)
  • This study was aimed to investigate whether systemic inflammatory reaction induced by insuflation of talc into the pleura can predict the outcome of pleurodesis. (mesothelioma-line.com)
  • Predictors of outcome of pleurodesis in patients with malignant pleural effusion: a systematic review and meta-analysis. (mesothelioma-line.com)
  • This systematic review aimed to examine available literature for studies investigating factors that predict pleurodesis outcome. (mesothelioma-line.com)
  • Available data do not suggest that chest tube size affects pleurodesis outcome. (mesothelioma-line.com)
  • Thoracic ultrasonography easily detects the movement of the visceral pleura on the parietal pleura This sign is absent when pleurodesis is successful. (clinicaltrials.gov)
  • Thoracic ultrasonography easily detects the sign of 'pleural sliding', due to the movement of the visceral pleura on the parietal pleura This sign is absent when pleurodesis is successful. (clinicaltrials.gov)
  • The value of thoracic ultrasound (TUS) imaging, before and after pleurodesis, in improving the quality and efficacy of care for patients with MPE remains unknown. (readbyqxmd.com)
  • Control group: Participants receive talc pleurodesis with no thoracic ultrasound imaging. (isrctn.com)
  • A study published in the Journal of Thoracic Disease showed the long-term benefits of talc pleurodesis. (mesotheliomaguide.com)
  • Only a subset of patients (42.3%) underwent pleurodesis, surgically (n=78) or by bedside instillation of sclerosants (n=87). (bmj.com)
  • Researchers compared the pain levels of people who underwent pleurodesis. (survivingmesothelioma.com)
  • In total, 112 patients underwent pleurodesis and follow-up data was obtained in 63 (56%) patients: 45 patients were available for clinical follow-up, 14 for telephone follow-up and four were dead. (ersjournals.com)
  • Moreover, surgical removal of parietal pleura is an effective way of achieving stable pleurodesis. (wikipedia.org)
  • Pleurodesis (also known as pleural sclerosis) involves instilling an irritant into the pleural space to cause inflammatory changes that result in bridging fibrosis between the visceral and parietal pleural surfaces, effectively obliterating the potential pleural space. (medscape.com)
  • All these measures are intended for provoking an inflammatory reaction of the parietal and visceral pleural surface that will promote obliteration of the pleural space (namely pleurodesis). (schmidtandclark.com)
  • Surgical Pleurodesis includes artificially irritating the parietal pleura which causes it to swell and adhere to the visceral pleural closing off the space between them. (mesotheliomaclaimslawcenter.com)
  • Pleurodesis approaches offer a limited course of treatment in pursuit of long-term control of the effusion, while indwelling pleural catheters offer minimally invasive long-term drainage with a lower chance of pleurodesis. (clinicaladvisor.com)
  • In addition to drainage of effusion, the use of an IPC may be followed by spontaneous pleurodesis that obviates the need for any additional chemical sclerosant. (hkmj.org)
  • 2 Conventional management options of MPE include thoracocentesis, chest tube drainage, and chemical and surgical pleurodesis. (hkmj.org)
  • Shorter duration of drainage will reduce the length of hospital stay without sacrificing the efficacy of pleurodesis. (qxmd.com)
  • In most cases, simple drainage will be sufficient treatment, but if they recur frequently or rapidly pleurodesis may be recommended. (virclinic.com)
  • Compare the effectiveness of video-assisted thoracoscopic cytoreductive pleurectomy vs talc pleurodesis, in terms of 1-year survival, in patients with suspected or proven malignant mesothelioma. (clinicaltrials.gov)
  • The mean survival in the talc pleurodesis group was 14 months compared to 17 and 24 months for the pleurectomy decortication (P/D) group and extrapleural pneumonectomy (EPP) group, respectively. (readbyqxmd.com)
  • After cytology revealed the presence of malignant breast cells, right-sided talc pleurodesis was performed. (pubmedcentralcanada.ca)
  • The patient had had recurrent episodes of primary spontaneous right-sided pneumothoraces 15 years earlier and underwent right-sided talc pleurodesis. (ochsnerjournal.org)
  • The aim of this study is to evaluate the effect of pleurodesis using ultrasound-guided iodopovidone sclerotherapy in hepatic hydrothorax. (scirp.org)
  • During his research block Ahmed will be looking for certain ultrasound markers that will allow clinicians to identify patients whose pleurodesis has been successful and can be discharged home earlier than the current practice. (ox.ac.uk)
  • 4 Chemical pleurodesis via an intercostal chest tube may entail prolonged hospitalisation and despite initial 'success', MPE often recurs a few months later. (hkmj.org)
  • The biggest disadvantage of a non-surgical pleurodesis is that the chest tube may be in place for several days, which is quite uncomfortable, prompting the need for painkillers. (schmidtandclark.com)
  • 1995). Talc slurry pleurodesis. (springer.com)
  • Talc produced unpredictable pleurodesis in both animal models with enduring pleural inflammation whether it was performed via slurry or poudrage. (spandidos-publications.com)
  • Improved Quality of Life in Patients with Malignant Pleural Effusion Following Videoassisted Thoracoscopic Talc Pleurodesis. (iiarjournals.org)
  • Talc pleurodesis is the most popular method to control symptoms of recurrent malignant pleural effusion. (knowcancer.com)
  • In patients with MPE, several interventions have been shown to be useful for palliation of the symptoms, including talc pleurodesis. (sigmaaldrich.com)
  • While pleurodesis does not treat cancer, it alleviates one of its most severe symptoms, which is difficulty breathing due to pleural effusion. (worthingtoncaron.com)
  • In this article we discuss the likely mechanisms of pleural inflammation and pleurodesis with emphasis on the systemic response due to the instillation of talc into the pleural space. (scielo.br)
  • We describe a case of a PET-positive pleural-based nodule after talc pleurodesis mimicking pleural malignancy and discuss the pathophysiology of reactive pleural inflammation after talc pleurodesis. (ochsnerjournal.org)
  • In conclusion, thoracoscopic large-particle talc pleurodesis is a feasible and effective treatment for MPE, significantly improving quality of life of patients. (iiarjournals.org)
  • 2002) Video-assisted thoracoscopic surgery with talc pleurodesis in the management of symptomatic hepatic hydrothorax. (scirp.org)
  • Our results show that the prognosis of patients after talc pleurodesis is independent of age, gender, type of malignancy and amount of pleural effusion, thus, suggesting the utility of treating all patients with symptomatic MPE early. (sigmaaldrich.com)
  • The purpose of this study was to analyze the usefulness of talc pleurodesis in improving QoL of patients with cancer and symptomatic MPE. (iiarjournals.org)
  • This review reports survival rates after talc pleurodesis in comparison to surgery in patients with malignant pleural mesothelioma. (readbyqxmd.com)
  • 2 An increased FDG uptake within the thickened pleura starts within 5 months after pleurodesis and continues until pleural calcification has developed. (ochsnerjournal.org)
  • All studies types reporting previously unpublished data on predictors of pleurodesis success were included. (mesothelioma-line.com)
  • PURPOSE: This randomized phase III trial is studying video-assisted surgery to see how well it works compared with talc pleurodesis in treating patients with malignant mesothelioma. (clinicaltrials.gov)
  • Comparison of additional minocycline versus iodopovidone pleurodesis during video-assisted thoracoscopic bleb. (amegroups.com)
  • We concluded that, nearly five decades after talcage pleurodesis, there can still be an ongoing inflammation reaction in the pleurae, which can be detected by FDG PET/CT. (hindawi.com)
  • Recently, biological mediators of inflammation [transforming growth factor β(TGF-β) and interferon] have been found to be effective in the production of pleurodesis. (springer.com)
  • 6 Similarly, antineoplastic agents (bleomycin), 7 immunostimulants ( Corynebacterium parvum and OK-432), 8,9 chemical irritants (talc and silver nitrate), 10,11 and more recently, biological mediators of inflammation (transforming growth factor beta (TGF- b ) and interferon) 12,13 have been effective in the production of pleurodesis. (scielo.br)
  • As pleurodesis causes systemic inflammation and is associated with considerable cost and morbidity during long-term follow up, the identification of patients who will experience an unsuccessful pleurodesis would be desirable. (mesothelioma-line.com)
  • The diagnosis of reactive inflammation of the pleural-based nodule after talc pleurodesis was established. (ochsnerjournal.org)
  • Pleurodesis is the conventional recommended treatment. (bmj.com)
  • Talc pleurodesis in pleuropulmonary diseases treatment. (ebscohost.com)
  • Pleurodesis is best utilized among mesothelioma patients decline other, more aggressive treatment options or who are not candidates for them. (mesotheliomacenter.org)
  • Talc pleurodesis is an effective treatment for malignant pleural effusion. (pubmedcentralcanada.ca)
  • Talc pleurodesis is a widely used technique for the treatment of MPE [ 2 ]. (pubmedcentralcanada.ca)
  • The best treatment is still debated, but talc remains the agent of choice to achieve pleurodesis. (iiarjournals.org)
  • Pleurodesis is the preferred palliative and supportive treatment option, targeting symptom relief. (readbyqxmd.com)
  • This type of treatment is called pleurodesis and it works by closing the space between pleura with talc or an antibiotic. (worthingtoncaron.com)
  • This study retrospectively compared long-term outcomes between two groups of breast cancer patients with malignant pleural effusion (MPE): those receiving only systemic therapy (ST) and those receiving ST following initial pleurodesis (P-ST). We identified 180 breast cancer patients from the National Cancer Center Hospital (Tokyo, Japan) database who had received ST and P-ST as an initial treatment for MPE between 1997 and 2008 for study inclusion. (elsevier.com)
  • This study is significant in the fact that it could lead to more widespread acceptance of the talc pleurodesis method, which could make pleural mesothelioma patients significantly more comfortable while undergoing treatment," said Russell Budd, managing director of mesothelioma law firm Baron and Budd. (prweb.com)
  • Viscum album extract is a new chemical agent for pleurodesis, and only a few studies have reported outcomes of such chemical pleurodesis in the treatment of malignant pleural effusion. (biomedcentral.com)
  • However, only a few studies have reported outcomes after its use for chemical pleurodesis in the treatment of malignant pleural effusion [ 3 - 5 ] and any serious side effect, such as acute pneumonitis, has not been described yet. (biomedcentral.com)
  • Secondary end points included safety, early postoperative results, and long-term effects of minocycline pleurodesis. (clinicaltrials.gov)
  • The patients were divided into two groups according to the chemical agents used for additional pleurodesis (iodopovidone versus minocycline). (amegroups.com)
  • This study confirmed the safety of both minocycline and iodopovidone for additional pleurodesis. (amegroups.com)
  • However, we carefully recommend minocycline over iodopovidone for pleurodesis because of faster postoperative recovery. (amegroups.com)
  • Among povidone-iodine group (n= 25) excellent pleurodesis (no. = 20), effective (n= 2) and weak pleurodesis (n= 3). (omicsonline.org)
  • They cite that the Medicines and Healthcare Products Regulatory Authority has recently completed an urgent review of the safety of talc as a pleurodesis agent for malignant effusion. (ebscohost.com)
  • Currently, new palliative treatments, such as talc pleurodesis, are being explored besides traditional surgery. (readbyqxmd.com)
  • If you are a mesothelioma patient suffering from breathlessness, talk to your doctor about pleurodesis surgery . (worthingtoncaron.com)