Pilot Projects: Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.Office Management: Planning, organizing, and administering activities in an office.Health Facility Administration: Management of the organization of HEALTH FACILITIES.Education, Distance: Education via communication media (correspondence, radio, television, computer networks) with little or no in-person face-to-face contact between students and teachers. (ERIC Thesaurus, 1997)Program Evaluation: Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.Remote Consultation: Consultation via remote telecommunications, generally for the purpose of diagnosis or treatment of a patient at a site remote from the patient or primary physician.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Program Development: The process of formulating, improving, and expanding educational, managerial, or service-oriented work plans (excluding computer program development).Health Education: Education that increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of health on a personal or community basis.Consumer Participation: Community or individual involvement in the decision-making process.Ontario: A province of Canada lying between the provinces of Manitoba and Quebec. Its capital is Toronto. It takes its name from Lake Ontario which is said to represent the Iroquois oniatariio, beautiful lake. (From Webster's New Geographical Dictionary, 1988, p892 & Room, Brewer's Dictionary of Names, 1992, p391)Telemedicine: Delivery of health services via remote telecommunications. This includes interactive consultative and diagnostic services.Computer Communication Networks: A system containing any combination of computers, computer terminals, printers, audio or visual display devices, or telephones interconnected by telecommunications equipment or cables: used to transmit or receive information. (Random House Unabridged Dictionary, 2d ed)Health Promotion: Encouraging consumer behaviors most likely to optimize health potentials (physical and psychosocial) through health information, preventive programs, and access to medical care.Cooperative Behavior: The interaction of two or more persons or organizations directed toward a common goal which is mutually beneficial. An act or instance of working or acting together for a common purpose or benefit, i.e., joint action. (From Random House Dictionary Unabridged, 2d ed)Information Systems: Integrated set of files, procedures, and equipment for the storage, manipulation, and retrieval of information.Developing Countries: Countries in the process of change with economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.Housing: Living facilities for humans.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.ComputersUser-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Data Collection: Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.United StatesQuestionnaires: Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.Focus Groups: A method of data collection and a QUALITATIVE RESEARCH tool in which a small group of individuals are brought together and allowed to interact in a discussion of their opinions about topics, issues, or questions.Mass Screening: Organized periodic procedures performed on large groups of people for the purpose of detecting disease.Attitude of Health Personnel: Attitudes of personnel toward their patients, other professionals, toward the medical care system, etc.Primary Health Care: Care which provides integrated, accessible health care services by clinicians who are accountable for addressing a large majority of personal health care needs, developing a sustained partnership with patients, and practicing in the context of family and community. (JAMA 1995;273(3):192)Population Surveillance: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.Health Knowledge, Attitudes, Practice: Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).Infant, Newborn: An infant during the first month after birth.Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.Human Genome Project: A coordinated effort of researchers to map (CHROMOSOME MAPPING) and sequence (SEQUENCE ANALYSIS, DNA) the human GENOME.Videoconferencing: Communications via an interactive conference between two or more participants at different sites, using computer networks (COMPUTER COMMUNICATION NETWORKS) or other telecommunication links to transmit audio, video, and data.Telecommunications: Transmission of information over distances via electronic means.Libraries: Collections of systematically acquired and organized information resources, and usually providing assistance to users. (ERIC Thesaurus, http://www.eric.ed.gov/ accessed 2/1/2008)Copyright: It is a form of protection provided by law. In the United States this protection is granted to authors of original works of authorship, including literary, dramatic, musical, artistic, and certain other intellectual works. This protection is available to both published and unpublished works. (from Circular of the United States Copyright Office, 6/30/2008)Computer Security: Protective measures against unauthorized access to or interference with computer operating systems, telecommunications, or data structures, especially the modification, deletion, destruction, or release of data in computers. It includes methods of forestalling interference by computer viruses or so-called computer hackers aiming to compromise stored data.Confidentiality: The privacy of information and its protection against unauthorized disclosure.Privacy: The state of being free from intrusion or disturbance in one's private life or affairs. (Random House Unabridged Dictionary, 2d ed, 1993)Licensure: The legal authority or formal permission from authorities to carry on certain activities which by law or regulation require such permission. It may be applied to licensure of institutions as well as individuals.Superstitions: A belief or practice which lacks adequate basis for proof; an embodiment of fear of the unknown, magic, and ignorance.Afipia: A genus of gram-negative, oxidase-positive, nonfermentative rods which are motile by means of a single flagellum. Afipia felis and BARTONELLA HENSELAE are causative agents of CAT-SCRATCH DISEASE. (From Bergey's Manual of Determinative Bacteriology, 9th ed)Seawater: The salinated water of OCEANS AND SEAS that provides habitat for marine organisms.Software: Sequential operating programs and data which instruct the functioning of a digital computer.New Caledonia: A group of islands in Melanesia constituting a French overseas territory. The group includes New Caledonia (the main island), Ile des Pins, Loyalty Island, and several other islet groups. The capital is Noumea. It was discovered by Captain Cook in 1774 and visited by various navigators, explorers, and traders from 1792 to 1840. Occupied by the French in 1853, it was set up as a penal colony 1864-94. In 1946 it was made a French overseas territory. It was named by Captain Cook with the 5th and 6th century A.D. Latin name for Scotland, Caledonia. (From Webster's New Geographical Dictionary, 1988, p830 & Room, Brewer's Dictionary of Names, 1992, p375)Organizations: Administration and functional structures for the purpose of collectively systematizing activities for a particular goal.Conservation of Natural Resources: The protection, preservation, restoration, and rational use of all resources in the total environment.Biodiversity: The variety of all native living organisms and their various forms and interrelationships.Desert Climate: A type of climate characterized by insufficient moisture to support appreciable plant life. It is a climate of extreme aridity, usually of extreme heat, and of negligible rainfall. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Climate Change: Any significant change in measures of climate (such as temperature, precipitation, or wind) lasting for an extended period (decades or longer). It may result from natural factors such as changes in the sun's intensity, natural processes within the climate system such as changes in ocean circulation, or human activities.

Methodological issues in biomonitoring of low level exposure to benzene. (1/12809)

Data from a pilot study on unmetabolized benzene and trans,trans muconic acid (t,t-MA) excretion in filling station attendants and unexposed controls were used to afford methodological issues in the biomonitoring of low benzene exposures (around 0.1 ppm). Urinary concentrations of benzene and t,t-MA were measured by dynamic head-space capillary GC/FID and HPLC, respectively. The accuracy of the HPLC determination of t,t-MA was assessed in terms of inter- and intra-method reliability. The adequacy of urinary t,t-MA and benzene as biological markers of low benzene exposure was evaluated by analysing the relationship between personal exposure to benzene and biomarker excretion. Filling station attendants excreted significantly higher amounts of benzene, but not of t,t-MA, than controls. Adjusting for occupational benzene exposure, smokers excreted significantly higher amounts of t,t-MA, but not of unmetabolized benzene, than nonsmokers. A comparative analysis of the present and previously published biomonitoring surveys showed a good inter-study agreement regarding the amount of t,t-MA and unmetabolized benzene excreted (about 0.1-0.2 mg/l and 1-2 micrograms/l, respectively) per unit of exposure (0.1 ppm). For each biomarker, based on the distribution of parameters observed in the pilot study, we calculated the minimum sample size required to estimate the population mean with given confidence and precision.  (+info)

Design and trial of a new questionnaire for occupational health surveys in companies. (2/12809)

In this article we present an example of our method for instrument development. This method is called the Development Cycle. It consists of four main stages: (1) defining the requirements for an instrument; (2) research, design and pilot testing; (3) implementation and (4) evaluation. An application of the Development Cycle was realized within a project for the development of a basic questionnaire about work and health, to be used at periodic health surveys. This questionnaire had to identify work and work-related health problems in employees with divergent occupations and working conditions. The design of the instrument and the results of its trial in 517 employees is presented. The evaluation of the test results and the modification of the questionnaire are discussed. From 1995, the questionnaire has been implemented in the Dutch OHS services quite successfully.  (+info)

A chiropractic service arrangement for musculoskeletal complaints in industry: a pilot study. (3/12809)

Chiropractic services are commonly used by workers with musculoskeletal problems, especially low back and neck complaints. Research into the effectiveness and cost-effectiveness of this approach is, however, difficult to design without prior pilot studies. This study followed 32 workers with these complaints attending one such service and used five measures of outcome over a 6-month period. These measured pain (VAS), disability (FLP), quality of life (SF-36), perceived benefit and satisfaction with care. Additionally, sickness costs to the companies were recorded over two years encompassing the study period. Treatment utilization was also monitored. Over half the population were chronic sufferers. The effect sizes were large for pain and for seven out of eight dimensions of the SF-36 questionnaire at 6-month follow-up, although not for disability (FLP). High levels of satisfaction and perceived improvement were reported and sickness costs to the companies fell. However, the sample size in this pilot study was small and did not include controls. We would, therefore, recommend a full cost-effectiveness study incorporating a randomized trial in this area.  (+info)

Biased JH usage in plasma cell immunoglobulin gene sequences from colonic mucosa in ulcerative colitis but not in Crohn's disease. (4/12809)

BACKGROUND: Ulcerative colitis is an inflammatory disease of the colonic and rectal mucosa. Autoantibodies have been observed in ulcerative colitis which may have a role in the pathogenesis of the disease. Evidence also suggests that there is an hereditary predisposition towards the disease, although no individual genes have been identified. AIMS: This is a pilot study of immunoglobulin heavy chain genes (IgH) in ulcerative colitis to determine whether they have any particular genetic characteristics which may lead to a better understanding of the disease aetiology. SUBJECTS: Colonic or rectal tissue was obtained from five children with ulcerative colitis. Tissue was also obtained from five children with Crohn's disease and five children who did not have inflammatory bowel disease as controls. METHODS: B cells and IgD+ B cells were identified by immunohistochemistry on frozen sections. Areas of lamina propria containing plasma cells, and areas of IgD+ B cells were microdissected. The immunoglobulin genes were PCR amplified, cloned, and sequenced. Sequences were analysed for content of somatic mutations and composition of heavy chain. RESULTS: An increase in the use of JH6 and DXP'1, and a decrease in the use of JH4, gene segments in immunoglobulin genes from lamina propria plasma cells, and from virgin IgD+ B cells, was found in patients with ulcerative colitis. These biases were not present in the control groups. CONCLUSIONS: There is a fundamental difference in the immunoglobulin genes from patients with ulcerative colitis. Whether this is caused by a difference in content of immunoglobulin gene segments in the germline or a difference in the recombination mechanism is not known.  (+info)

Use of positron emission tomography in evaluation of brachial plexopathy in breast cancer patients. (5/12809)

18-Fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) has previously been used successfully to image primary and metastatic breast cancer. In this pilot study, 19 breast cancer patients with symptoms/signs referrable to the brachial plexus were evaluated with 18FDG-PET. In 11 cases computerized tomography (CT) scanning was also performed. Of the 19 patients referred for PET study, 14 had abnormal uptake of 18FDG in the region of the symptomatic plexus. Four patients had normal PET studies and one had increased FDG uptake in the chest wall that accounted for her axillary pain. CT scans were performed in 9 of the 14 patients who had positive brachial plexus PET studies; six of these were either normal or showed no clear evidence of recurrent disease, while three CTs demonstrated clear brachial plexus involvement. Of two of the four patients with normal PET studies, one has had complete resolution of symptoms untreated while the other was found to have cervical disc herniation on magnetic resonance imaging (MRI) scan. The remaining two patients almost certainly had radiation-induced plexopathy and had normal CT, MRI and PET study. These data suggest that 18FDG-PET scanning is a useful tool in evaluation of patients with suspected metastatic plexopathy, particularly if other imaging studies are normal. It may also be useful in distinguishing between radiation-induced and metastatic plexopathy.  (+info)

Marimastat in recurrent colorectal cancer: exploratory evaluation of biological activity by measurement of carcinoembryonic antigen. (6/12809)

Marimastat is a specific inhibitor of matrix metalloproteinases that has been shown to be effective in cancer models. A pilot, escalating-dose study of oral marimastat was performed in patients with recurrent colorectal cancer, in whom evaluation of serological response was made by measurement of carcinoembryonic antigen (CEA) levels. The study assessed the safety and tolerability of 4 weeks administration of marimastat, and determined a dose range producing detectable serological effects. Patients were recruited with a serum CEA level greater than 5 ng ml(-1), and rising by more than 25% over a 4-week screening period. Patients were treated for 28 days and entered into a continuation protocol if a serological response or clinical benefit was observed. Pharmacokinetic and safety data determined that groups of patients were recruited sequentially at 25 mg and 50 mg twice daily, and, thereafter, 10 mg twice daily, 10 mg once daily, 5 mg once daily and 20 mg once daily. A biological effect (BE) was defined as a CEA value on day 28 no greater than on day 0; a partial biological effect (PBE) was defined as a rise in CEA over the 28-day treatment period of less than 25%. Of 70 patients recruited, 63 completed the 28-day treatment period, and 55 were eligible for cancer antigen analysis. Examination of the dose-effect relationships provides evidence for a causal relationship between marimastat and biological effects: the proportion of patients with BE or PBE was higher with twice daily dosing (16 out of 25, 64%) than with once daily dosing (11 out of 30, 37%) (P = 0.043, chi2 test). Furthermore, the median rates of rise of CEA fell markedly during treatment compared with the screening period for patients receiving twice daily marimastat (P<0.0001), but not for patients receiving marimastat once daily (P = 0.25). Musculoskeletal adverse events emerged as the principal drug-related toxicity of marimastat, occurring in a dose- and time-dependent fashion. It was concluded that marimastat was associated with dose-dependent biological effects in cancer patients. The occurrence of musculoskeletal side-effects define 25 mg twice daily as the upper limit of the dose range for continuous use in further studies. Therefore, a dose range of 20 mg once daily to 25 mg twice daily seems appropriate for further studies, which should aim to demonstrate the efficacy of the drug in terms of conventional clinical end points and describe the long-term tolerability of this novel agent.  (+info)

Reactions to medical abortion among providers of surgical abortion: an early snapshot.(7/12809)


X-chromosome inactivation patterns do not implicate asymmetric splitting of the inner cell mass in the aetiology of twin-twin transfusion syndrome. (8/12809)

The aetiology of twin-twin transfusion syndrome (TTTS) is unclear. We investigated the hypothesis that monochorionic (MC) pregnancies with TTTS are associated with differences in the timing and symmetry of twinning compared to MC twin pregnancies without TTTS. DNA was extracted from the umbilical cord vessels of 26 female MC twins, 14 with and 12 without TTTS on serial antenatal ultrasound. X-inactivation patterns were determined by DNA digestion with Hhal and Hpall followed by polymerase chain reaction for a polymorphic trinucleotide repeat in the androgen receptor gene. Products were quantified by densitometry and results compared to those in peripheral blood samples of adult female controls. The median degree of non-random inactivation was similar in MC twins with TTTS, in MC twins without TTTS, and in adult controls. The percentage of individuals with skewed (> or =30/70%) inactivation patterns was no different in MC twins with TTTS compared to those without TTTS, and was similar to adult controls using either enzyme technique. In conclusion we found no difference in the degree or frequency of non-random X-inactivation patterns in TTTS. X-inactivation patterns do not appear to be a useful tool for studying the symmetry of inner cell mass splitting in monochorionic twins.  (+info)

  • Agencies, stakeholders, and the Government Accountability Office (GAO) all have suggested, as an alternative to large-scale reform, that pilot projects be conducted to test the effectiveness of alternatives to the current Part 1614 process. (eeoc.gov)
  • The project has brought together City staff and key stakeholders including Visit Oakland , the Lake Merritt/Uptown Business Improvement District (BID) , the Downtown BID and the Jack London BID. (localwiki.org)
  • The GAO report stressed the importance of a "sound evaluation plan" to determine whether the pilot could become a successful alternative to the current regulatory process. (eeoc.gov)
  • The Pilot Project will run for 3 years, from 2019-2021 and, if approved by the ABMS, the ABPN plans to transition diplomates into this program in 2022 as a permanent alternative to the secure MOC examination. (abpn.com)
  • After completion of the pilot project (expected to be the end of the 2nd quarter of 2019), the results will be made available to all project partners. (kalmarglobal.it)
  • Speaking at a CRC Breakfast Forum, Genomics - sheep breeding's holy grail, which opened the official LambEx program, CRC Chief Executive James Rowe told the crowd of nearly 400 that the new pilot projects would pave the way for the commercialisation of new DNA tests for breeding traits, horned/polled, and parentage. (sheepcrc.org.au)
  • Once available to all diplomates, the Pilot Project will ultimately provide greater flexibility to ABPN diplomates for meeting their MOC Part III program requirements. (abpn.com)
  • This project is funded by a State of California Infill and Infrastructure Program grant. (localwiki.org)
  • For any questions about the Hope Center Pilot Project Program, contact Anneliese Schaefer, [email protected] . (wustl.edu)
  • The pilot project, at a copper mine in Latin America, aims to create a digital standard for improved machine efficiency, reliability and competitiveness for industrial customers. (wordpress.com)
  • According to GAO, such a plan must include clear objectives, measures linked to those objectives, criteria for determining performance, a method for isolating the effects of the pilot programs, a data analysis plan, and a data collection/storage/entry plan to ensure that the results are reliable. (eeoc.gov)
  • The ABPN MOC Part III Pilot Project is a professional journal article-based assessment activity designed as an optional alternative to the current secure, proctored 10-year MOC examination. (abpn.com)
  • See the 'Part III Pilot' section in your ABPN Physician Folios account. (abpn.com)
  • If you received a Pilot Project invitation and still want to enroll, please see the 'Part III Pilot' section in your ABPN Physician Folios account. (abpn.com)
  • Journal article lists are also in the ABPN Physician Folios 'Part III Pilot' section for eligible participants. (abpn.com)
  • The Sheep CRC is developing two new Genomics Pilot Projects, the first offering participants a new parentage test that will also provide prediction of horn-poll, while the second will be a genotyping test for a broad range of traits in young sires," Prof. Rowe said. (sheepcrc.org.au)
  • Exam questions are now available to enrolled Pilot Project participants, who were sent an email in January about accessing topics, articles, and questions. (abpn.com)
  • This toolkit provides helpful information for agencies on how to apply for a variance to conduct a pilot project consistent with 29 C.F.R. § 1614.102(f) and MD-110 Chapter 1 Section X. (eeoc.gov)
  • In explaining the Commission's rationale for pilot projects, the Final Rule preamble noted that all agencies and several other commenters supported the change, and that pilot projects could provide "helpful data for future recommendations regarding changes to the federal sector EEO complaint process. (eeoc.gov)
  • Since the publication of MD-110, agencies have requested that EEOC provide even more information about variances and pilot projects consistent with 29 C.F.R. § 1614.102(f) and MD-110. (eeoc.gov)
  • Pilots fly fixed wing aircraft and helicopters to provide air transportation and other services. (monsterindia.com)
  • The nine uses of pilot projects within the Research, Managerial and Political-Entrepreneurial categories, depicted on a scale from 0 (absent) to 5 (strongly present) for the INSIDE pilot project. (ecologyandsociety.org)
  • Two new genomic pilot projects to advance the delivery of DNA-based breeding tools have been announced at LambEx today [June by the Cooperative Research Centre for Sheep Industry Innovation (Sheep CRC). (sheepcrc.org.au)
  • For publications arising from research supported by a Hope Center Pilot Project Award, please acknowledge this support. (wustl.edu)
  • The objective of this pilot is to demonstrate the ecological and economic merits of the restoration strategy outlined by Drs. Norm Johnson and Jerry Franklin within the Roseburg District. (blm.gov)
  • In February 2012, the BLM released a report regarding the Drs. Johnson and Franklin's observations about the Forestry Pilot Projects. (blm.gov)
  • The GAO also studied the issue and recommended that EEOC allow pilot projects in an August 2009 report, titled, "Pilot Projects Could Help Test Solutions to Long-Standing Concerns with the EEO Complaint Process. (eeoc.gov)
  • Retired Conservative Senator Michael Meighen says it's time for governments to set up pilot projects across Canada to give a basic income guarantee a chance as future policy. (basicincomecanada.org)
  • The T3 Network pilot projects are organized into three specific areas of focus - Open Data Standards, Competency-Based Learning and Hiring, and Empowering Learners and Workers. (uschamberfoundation.org)
  • Comprehensive Learner/Worker/Military Record Standards - Align and pilot test the use of data standards to enable individuals to better manage and use competencies documented in their records to pursue career and educational opportunities. (uschamberfoundation.org)
  • Below you can find more technical information, photos, AIS data and last 5 port calls of PILOT PROJECT detected by AIS. (vesselfinder.com)
  • However, it's unclear who would be bankrolling these pilot projects, with two likely funders--GAVI and the Global Fund to Fight AIDS, Tuberculosis and Malaria--saying in a joint statement on Friday that they were still undecided on whether they would support the vaccine in conjunction with other interventions. (fiercepharma.com)
  • Read what our diplomates are saying about the Pilot Project. (abpn.com)
  • If the Pilot becomes a permanent option in 2022, diplomates who continue with the journal article-based assessment option will be expected to read a set number of articles every three years on an ongoing basis. (abpn.com)
  • The workgroup reached no consensus on large scale reform, but instead recommended, among other changes, that EEOC allow agencies to perform pilot projects to test potential alternatives. (eeoc.gov)
  • Pilot projects will test the vaccine's efficacy in a real-world setting versus a carefully controlled clinical trial setting. (fiercepharma.com)
  • We've collaborated with the community to put together to put a range of pilot projects in the Corrimal Town Centre and Memorial Park to the test, and want to find out whether you think they've been successful. (nsw.gov.au)
  • That's where pilot projects come in - we have to test it," says Meighen, who notes that if the pilots are successful, then the policy becomes easier to sell, politically. (basicincomecanada.org)
  • This session will showcase a variety of strategies for pilot plant design, operation, and even outsourcing that enhance pharmaceutical process development. (aiche.org)
  • The project will include the elements of active management proposed by the US Fish and Wildlife Service (USFWS) for the recovery of the Northern Spotted Owl. (blm.gov)
  • The EEOC created a process to approve agency pilot projects in its 2012 amendments to Part 1614 and 2015 edits to Management Directive 110. (eeoc.gov)
  • EEOC provided further guidance for agencies on how to request a variance and create a pilot project in a revised Management Directive 110 (MD-110). (eeoc.gov)
  • Please help support our staff while they're unable to serve your favorite drinks at Pilot for the next few weeks. (gofundme.com)
  • Noting the trend towards the use of community -based education for JICWL, and in line with the commitment of Vietnam in complying with international law and policy, the Vietnamese government, together with UNICEF, established a pilot project on non-custodial measures, reintegration and support services to JICWL in Hai Phong. (unicef.org)
  • It is because of leadership and support from the District Administration that the S afe to Learn Community Pilot Project was possible. (safetolearn.com)
  • Because of Lamar Consolidated Independent School District's (LCISD) dedication to emergency preparedness and school safety, LCISD was selected to participate in the Safe to Learn © Community Pilot Project. (safetolearn.com)