Seasonal variation in the essential oil of Pilocarpus microphyllus Stapf. (1/4)
The essential oils of the leaves and fine stems of Pilocarpus microphyllus, collected on iron mineralized soil of the Serra de Caraj s, Southeast of Par State, Brazil, during the rainy and dry seasons, were obtained by hydrodistillation and analyzed by GC-MS. The main identified compounds were 2-tridecanone, beta-caryophyllene, 2-pentadecanone, caryophyllene oxide and germacrene D. Their percentage contents varied with the season, the greater values having been detected mainly in the rainy season. For 2-tridecanone and beta-caryophyllene the higher values were observed in the fine stem oils for the former, and in the leaf oils for the latter. For 2-pentadecanone, caryophyllene oxide and germacrene D they were also in the leaf oils. In general, the leaf oils were very distinguishable from those of fine stem oils, even in the same specimen. (+info)Insecticidal activity of 2-tridecanone against the cowpea weevil Callosobruchus maculatus (Coleoptera: Bruchidae). (2/4)
The effect of 2-tridecanone vapor on the cowpea weevil (Callosobruchus maculatus) development was determined. Seeds of cowpea were infested with adults and exposed to different doses of 2-tridecanone isolated from Pilocarpus microphyllus Stapf ex Holm, a plant species native from northeastern Brazil. The pure monoterpene was evaluated both undiluted as well as in the dilutions 1:10, 1:100 and 1:1,000 (v/v). The following parameters of the cowpea weevil life cycle were analyzed in response to decreasing doses of 2-tridecanone: number of eggs laid, percentage of egg hatching on seeds, percentage of adult emergence, adult weight at emergence, mean developmental time and number of adults emerged. Vapor of 2-tridecanone caused a significant (P < 0.05) reduction in the number of eggs laid, in the percentage of eggs hatched and in the number of emerged adults in infested seeds. The fumigant insecticidal effect of 2-tridecanone was mainly due to its ovicidal activity. (+info)HPLC-ESI-MS/MS of imidazole alkaloids in Pilocarpus microphyllus. (3/4)
Pilocarpine, an important imidazole alkaloid, is extracted from the leaves of Pilocarpus microphyllus (Rutaceae), known in Brazil as jaborandi and used mainly for the treatment of glaucoma. Jaborandi leaves also contain other imidazole alkaloids, whose pharmacological and physiological properties are unknown, and whose biosynthetic pathways are under investigation. In the present study, a HPLC method coupled with ESI-MS(n) was developed for their qualitative and quantitative analysis. This method permits the chromatographic separation of the imidazole alkaloids found in extracts of jaborandi, as well as the MS/MS analysis of the individual compounds. Thus two samples: leaves of P. microphyllus and a paste that is left over after the industrial extraction of pilocarpine; were compared. The paste was found to contain significant amounts of pilocarpine and other imidazole alkaloids, but had a slightly different alkaloid profile than the leaf extract. The method is suitable for the routine analysis of samples containing these alkaloids, as well as for the separation and identification of known and novel alkaloids from this family, and may be applied to further studies of the biosynthetic pathway of pilocarpine in P. microphyllus. (+info)Endogenous neurosteroid synthesis modulates seizure frequency. (4/4)
(+info)Pilocarpus is not a medical condition or diagnosis, but rather it refers to a type of plant genus (Pilocarpus spp.) that contains several species of shrubs and small trees. The most well-known species in this genus is Pilocarpus jaborandi, which is native to South America.
Extracts from the leaves of Pilocarpus plants contain a chemical compound called pilocarpine, which has been used medically for its parasympathomimetic effects. Specifically, it can stimulate the parasympathetic nervous system, leading to increased salivation, sweating, and contraction of the smooth muscles in the eyes and gastrointestinal tract.
Pilocarpine is primarily used in medical practice to treat dry mouth (xerostomia) caused by radiation therapy or certain medications, as well as to reduce intraocular pressure in patients with glaucoma. It can be administered orally, topically (as eye drops), or sublingually (under the tongue).
Therefore, a medical definition of Pilocarpus would refer to a genus of plants that contain pilocarpine, a compound used in medical treatments for its parasympathomimetic effects.
Pilocarpus
Pilocarpus microphyllus
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Jaborandi
P. microphyllus
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Jaborandi3
- Pilocarpus microphyllus (Jaborandi) treats vertigo, nausea when looking at moving objects and associated tinnitus. (sinuswars.com)
- In the nineteenth century, the Guajajara tribe of Brazil discovered the medicinal qualities of a native plant called Pilocarpus jaborandi. (emory.edu)
- With the scientific name of Pilocarpus microphyllus, it belongs to the family of rutaceae and has as popular names pepper of the dog, ibirataío jaborandi and true jaborandi. (wipesleep.com)
Microphyllus1
- Seasonal variation in the essential oil of Pilocarpus microphyllus Stapf. (ufpa.br)
Germplasm Resourc1
- Pilocarpus racemosus in the Germplasm Resources Information Network (GRIN) , U.S. Department of Agriculture Agricultural Research Service. (wikimedia.org)
Species1
- Pilocarpus is a genus of about 13 species of plants belonging to the family Rutaceae, native to the Neotropics of South America. (wikipedia.org)
Pilocarpine4
- Pilocarpine heeft een sterk zweetdrijvend effect en kan verder 'flushing' (een gevoel van warmte dat gepaard gaat met zichtbare roodheid van de huid), hoofdpijn, misselijkheid en gezichtsstoornissen veroorzaken. (krachtigeplanten.nl)
- The main active ingredi- ent of Pilocarpus is pilocarpine. (urenus.com)
- Pilocarpus, Pilocarpine. (google.dk)
- Pilocarpine (1), a secondary metabolite of several Pilocarpus species, is a therapeutically used partial agonist of muscarinic acetylcholine receptors (mAChRs). (bvsalud.org)
Fluid Extract of Pilocarpus1
- Fluid Extract of Pilocarpus. (henriettes-herb.com)
RUTACEAE1
- Pilocarpus is a genus of about 13 species of plants belonging to the family Rutaceae, native to the Neotropics of South America. (wikipedia.org)
Jaborandii leaf1
- Your search for PILOCARPUS JABORANDII LEAF did not return any results. (nih.gov)
Pennatifolius1
- Zur Anatomie der Blüten von Pilocarpus pennatifolius Lem. (nih.gov)