Chemicals and DrugsPhenomena and ProcessesInformation Science
PhosphotransferasesKanamycin KinasePhosphotransferases (Paired Acceptors)Phosphotransferases (Alcohol Group Acceptor)EthanolaminephosphotransferaseAminoglycosidesDiacylglycerol CholinephosphotransferasePhosphotransferases (Phosphomutases)Phosphotransferases (Carboxyl Group Acceptor)Phosphotransferases (Nitrogenous Group Acceptor)Phosphotransferases (Phosphate Group Acceptor)Amino Acid SequenceSubstrate SpecificityMolecular Sequence DataKinetics
Phosphotransferases
A rather large group of enzymes comprising not only those transferring phosphate but also diphosphate, nucleotidyl residues, and others. These have also been subdivided according to the acceptor group. (From Enzyme Nomenclature, 1992) EC 2.7.
Kanamycin Kinase
A class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (AMINOGLYCOSIDES) by regiospecific PHOSPHORYLATION of the 3' and/or 5' hydroxyl.
Phosphotransferases (Paired Acceptors)
A group of enzymes that transfers two phosphate groups from a donor such as ATP to two different acceptors. (From Enzyme Nomenclature, 1992) EC 2.7.9.
Phosphotransferases (Alcohol Group Acceptor)
A group of enzymes that transfers a phosphate group onto an alcohol group acceptor. EC 2.7.1.
Ethanolaminephosphotransferase
An enzyme that catalyzes reversibly the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to yield phosphatidylethanolamine (cephalin) and CMP. The enzyme is found in the endoplasmic reticulum. EC 2.7.8.1.
Aminoglycosides
Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.
Diacylglycerol Cholinephosphotransferase
An enzyme that catalyzes the synthesis of phosphatidylcholines from CDPcholine and 1,2-diacylglycerols. EC 2.7.8.2.
Phosphotransferases (Phosphomutases)
A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2.
Phosphotransferases (Carboxyl Group Acceptor)
A class of enzymes that transfers phosphate groups and has a carboxyl group as an acceptor. EC 2.7.2.
Phosphotransferases (Nitrogenous Group Acceptor)
A group of enzymes that catalyzes the transfer of a phosphate group onto a nitrogenous group acceptor. EC 2.7.3.
Phosphotransferases (Phosphate Group Acceptor)
A group of enzymes that catalyzes the transfer of a phosphate group onto a phosphate group acceptor. EC 2.7.4.
Amino Acid Sequence
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
Substrate Specificity
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
Molecular Sequence Data
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Kinetics
The rate dynamics in chemical or physical systems.

A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. (1/3825)

We have identified a novel fibroblast growth factor receptor 3 (FGFR3) missense mutation in four unrelated individuals with skeletal dysplasia that approaches the severity observed in thanatophoric dysplasia type I (TD1). However, three of the four individuals developed extensive areas of acanthosis nigricans beginning in early childhood, suffer from severe neurological impairments, and have survived past infancy without prolonged life-support measures. The FGFR3 mutation (A1949T: Lys650Met) occurs at the nucleotide adjacent to the TD type II (TD2) mutation (A1948G: Lys650Glu) and results in a different amino acid substitution at a highly conserved codon in the kinase domain activation loop. Transient transfection studies with FGFR3 mutant constructs show that the Lys650Met mutation causes a dramatic increase in constitutive receptor kinase activity, approximately three times greater than that observed with the Lys650Glu mutation. We refer to the phenotype caused by the Lys650Met mutation as "severe achondroplasia with developmental delay and acanthosis nigricans" (SADDAN) because it differs significantly from the phenotypes of other known FGFR3 mutations.  (+info)

Presynaptic inhibition of GABA(B)-mediated synaptic potentials in the ventral tegmental area during morphine withdrawal. (2/3825)

Opioids increase the firing of dopamine cells in the ventral tegmental area by presynaptic inhibition of GABA release. This report describes an acute presynaptic inhibition of GABAB-mediated IPSPs by mu- and kappa-opioid receptors and the effects of withdrawal from chronic morphine treatment on the release of GABA at this synapse. In slices taken from morphine-treated guinea pigs after washing out the morphine (withdrawn slices), a low concentration of a mu receptor agonist increased, rather than decreased, the amplitude of the GABAB IPSP. In withdrawn slices, after blocking A1-adenosine receptors with 8-cyclopentyl-1, 3-dipropylxantine, mu-opioid receptor activation inhibited the IPSP at all concentrations and increased the maximal inhibition. In addition, during withdrawal, there was a tonic increase in adenosine tone that was further increased by forskolin or D1-dopamine receptor activation, suggesting that metabolism of cAMP was the source of adenosine. The results indicate that during acute morphine withdrawal, there was an upregulation of the basal level of an opioid-sensitive adenylyl cyclase. Inhibition of this basal activity by opioids had two effects. First, a decrease in the formation of cAMP that decreased adenosine tone. This effect predominated at low mu receptor occupancy and increased the amplitude of the IPSP. Higher agonist concentrations inhibited transmitter release by both kinase-dependent and -independent pathways. This study indicates that the consequences of the morphine-induced upregulation of the cAMP cascade on synaptic transmission are dependent on the makeup of receptors and second messenger pathways present on any given terminal.  (+info)

The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. (3/3825)

In male germ cells many mRNAs are sequestered by proteins into translationally silent messenger ribo-nucleoprotein (mRNP) particles. These masked paternal mRNAs are stored and translated at specific times of germ cell development. Little is known about the mammalian testicular mRNA masking proteins bound to non-polysomal mRNAs. In this report, the major proteins binding to non-polysomal testicular mRNAs were isolated and analyzed. The two predominant proteins identified were: a Y-box protein (MSY2), the mammalian homolog to the Xenopus oocyte masking protein FRGY2/mRNP3+4, and a poly(A) binding protein. A kinase activity was also found associated with these non-polysomal RNAs. The kinase co-immunoprecipitates with MSY2 and phosphorylates MSY2 in vitro. The MSY2 associated kinase is not casein kinase 2, the kinase believed to phosphorylate mRNP3+4 in oocytes, but a yet unidentified kinase. MSY2 was found to be phosphorylated in vivo and MSY2 dephosphorylation led to a decrease in its affinity to bind RNA as judged by northwestern blotting. Therefore, testicular masked mRNAs may be regulated by the phosphorylation state of MSY2. Reconstitution experiments in which non-polysomal mRNA-binding proteins are dissociated from their RNAs and allowed to bind to exogenous mRNAs suggest that MSY2 binds RNA in a sequence-independent fashion. Furthermore, association of the non-polysomal derived proteins to exogenous non-specific mRNAs led to their translational repression in vitro.  (+info)

A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases. (4/3825)

Sequence analysis of the probable archaeal phosphoglycerate mutase resulted in the identification of a superfamily of metalloenzymes with similar metal-binding sites and predicted conserved structural fold. This superfamily unites alkaline phosphatase, N-acetylgalactosamine-4-sulfatase, and cerebroside sulfatase, enzymes with known three-dimensional structures, with phosphopentomutase, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, phosphoglycerol transferase, phosphonate monoesterase, streptomycin-6-phosphate phosphatase, alkaline phosphodiesterase/nucleotide pyrophosphatase PC-1, and several closely related sulfatases. In addition to the metal-binding motifs, all these enzymes contain a set of conserved amino acid residues that are likely to be required for the enzymatic activity. Mutational changes in the vicinity of these residues in several sulfatases cause mucopolysaccharidosis (Hunter, Maroteaux-Lamy, Morquio, and Sanfilippo syndromes) and metachromatic leucodystrophy.  (+info)

The cellular distribution and kinase activity of the Cdk family member Pctaire1 in the adult mouse brain and testis suggest functions in differentiation. (5/3825)

Pctaire1, a member of the family of cyclin-dependent kinases, has been shown to be particularly abundantly expressed in differentiated tissues such as testis and brain. However, very little is known about the cellular and subcellular distribution and function of Pctaire1 protein(s), which is the focus of this study. We show that Pctaire1 encoded two major proteins of M(r) approximately 62,000 and approximately 68,000, found predominantly in testis and brain. Within these two tissues, Pctaire1 was most abundant in the cytoplasm of terminally differentiated cells, notably, the pyramidal neurons in brain and elongated spermatids in testis. Immunoprecipitation experiments further showed that a kinase activity toward myelin basic protein was associated with Pctaire1 in the adult testis and brain and that its activity was potentially regulated through association with regulatory partner(s). These results suggest that Pctaire1 kinase might have an important role in differentiated cells such as postmitotic neurons and spermatogenic cells.  (+info)

Involvement of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system in regulation of transcription of catabolic genes. (6/3825)

Synthesis of catabolite-sensitive enzymes is repressed in mutants defective in the general proteins (enzyme I and HPr) of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system (ptsI and ptsH mutations). To elucidate the mechanism of this phenomenon we constructed isogenic strains carrying pts mutations as well as different lesions of regulation of the lac operon or mutations affecting adenylate cyclase activity (cya mutation) and synthesis of cyclic AMP-receptor protein (crp mutation) Measurements of the differential rate of beta-galactosidase synthesis in these strains showed that the repressive effect of pts mutations was revealed in lac+, lacI, lacOc and cya bacteria, but it was lost in lacP and crp strains. It was concluded that mutational damage to the general components of the phosphoenolpyruvate-dependent phosphotransferase system diminishes activity of the lac promoter. The results obtained led to the conclusion that pts gene products (apparently phospho approximately HPr) are necessary for the initiation of transcription of catabolite-sensitive operons in E. coli.  (+info)

In vivo regulation of glycolysis and characterization of sugar: phosphotransferase systems in Streptococcus lactis. (7/3825)

Two novel procedures have been used to regulate, in vivo, the formation of phosphoenolpyruvate (PEP) from glycolysis in Streptococcus lactis ML3. In the first procedure, glucose metabolism was specifically inhibited by p-chloromercuribenzoate. Autoradiographic and enzymatic analyses showed that the cells contained glucose 6-phosphate, fructose 6-phosphate, fructose-1,6-diphosphate, and triose phosphates. Dithiothreitol reversed the p-chloromercuribenzoate inhibition, and these intermediates were rapidly and quantitatively transformed into 3- and 2-phosphoglycerates plus PEP. The three intermediates were not further metabolized and constituted the intracellular PEP potential. The second procedure simply involved starvation of the organisms. The starved cells were devoid of glucose 6-phosphate, fructose 6-phosphate, fructose- 1,6-diphosphate, and triose phosphates but contained high levels of 3- and 2-phosphoglycerates and PEP (ca. 40 mM in total). The capacity to regulate PEP formation in vivo permitted the characterization of glucose and lactose phosphotransferase systems in physiologically intact cells. Evidence has been obtained for "feed forward" activation of pyruvate kinase in vivo by phosphorylated intermediates formed before the glyceraldehyde-3-phosphate dehydrogenase reaction in the glycolytic sequence. The data suggest that pyruvate kinase (an allosteric enzyme) plays a key role in the regulation of glycolysis and phosphotransferase system functions in S. lactis ML3.  (+info)

A phosphotransferase that generates phosphatidylinositol 4-phosphate (PtdIns-4-P) from phosphatidylinositol and lipid A in Rhizobium leguminosarum. A membrane-bound enzyme linking lipid a and ptdins-4-p biosynthesis. (8/3825)

Membranes of Rhizobium leguminosarum contain a 3-deoxy-D-manno-octulosonic acid (Kdo)-activated lipid A 4'-phosphatase required for generating the unusual phosphate-deficient lipid A found in this organism. The enzyme has been solubilized with Triton X-100 and purified 80-fold. As shown by co-purification and thermal inactivation studies, the 4'-phosphatase catalyzes not only the hydrolysis of (Kdo)2-[4'-32P]lipid IVA but also the transfer the 4'-phosphate of Kdo2-[4'-32P]lipid IVA to the inositol headgroup of phosphatidylinositol (PtdIns) to generate PtdIns-4-P. Like the 4'-phosphatase, the phosphotransferase activity is not present in Escherichia coli, Rhizobium meliloti, or the nodulation-defective mutant 24AR of R. leguminosarum. The specific activity for the phosphotransferase reaction is about 2 times higher than that of the 4'-phosphatase. The phosphotransferase assay conditions are similar to those used for PtdIns kinases, except that ATP and Mg2+ are omitted. The apparent Km for PtdIns is approximately 500 microM versus 20-100 microM for most PtdIns kinases, but the phosphotransferase specific activity in crude cell extracts is higher than that of most PtdIns kinases. The phosphotransferase is absolutely specific for the 4-position of PtdIns and is highly selective for PtdIns as the acceptor. The 4'-phosphatase/phosphotransferase can be eluted from heparin- or Cibacron blue-agarose with PtdIns. A phosphoenzyme intermediate may account for the dual function of this enzyme, since a single 32P-labeled protein species (Mr approximately 68,000) can be trapped and visualized by SDS gel electrophoresis of enzyme preparations incubated with Kdo2-[4'-32P]lipid IVA. Although PtdIns is not detected in cultures of R. leguminosarum/etli (CE3), PtdIns may be synthesized during nodulation or supplied by plant membranes, given that soybean PtdIns is an excellent phosphate acceptor. A bacterial enzyme for generating PtdIns-4-P and a direct link between lipid A and PtdIns-4-P biosynthesis have not been reported previously.  (+info)

selenophosphate synthetase Summary Report | CureHunterselenophosphate synthetase Summary Report | CureHunter
selenophosphate synthetase: involved in selenium metabolism; gamma-phosphate of ATP is transferred to HSe resulting in formation of monoselenophosphate; amino acid sequence in first source
http://www.curehunter.com/public/keywordSummaryC062762-selenophosphate-synthetase.do
Phosphotransferases (Alcohol Group Acceptor) | REACH
Tabeling C, Yu H, Wang L, Ranke H, Goldenberg NM, Zabini D, Noe E, Krauszman A, Gutbier B, Yin J, Schaefer M, Arenz C, Hocke AC, Suttorp N, Proia RL, Witzenrath M, Kuebler WM. CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction. Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13):E1614-23 ...
https://reach.sickkids.ca/display/6032
anti-SEPHS2 antibody | GeneTexanti-SEPHS2 antibody | GeneTex
SEPHS2 antibody (selenophosphate synthetase 2) for ICC/IF, IHC-P, WB. Anti-SEPHS2 pAb (GTX103766) is tested in Human samples. 100% Ab-Assurance.
http://www.genetex.com/SEPHS2-antibody-GTX103766.html
phospho-N-acetylmuramoyl pentapeptide transferase Summary Report | CureHunterphospho-N-acetylmuramoyl pentapeptide transferase Summary Report | CureHunter
phospho-N-acetylmuramoyl pentapeptide transferase: enzyme important in murein synthesis which transfers the N-acetylmuramoylpentapeptide to a membrane-bound carrier that is a C-55 terpene alcohol phosphate; minor descriptor (75-84); on-line & Index Medicus search PHOSPHOTRANSFERASES (75-84)
http://www.curehunter.com/public/keywordSummaryC100130-phospho-N-acetylmuramoyl-pentapeptide-transferase.do
Herpes Simplex Virus Specified Deoxypyrimidine Kinase and the Uptake of Exogenous Nucleosides by Infected Cells | Microbiology...Herpes Simplex Virus Specified Deoxypyrimidine Kinase and the Uptake of Exogenous Nucleosides by Infected Cells | Microbiology...
Summary Herpes simplex virus can confer to thymidine kinaseless cells the ability to incorporate exogenously supplied thymidine into acid precipitable material. However no incorporation of exogenously supplied deoxycytidine into acid precipitable material can be detected after infection of deoxycytidine kinaseless cells by herpes simplex virus. This failure to incorporate exogenous deoxycytidine is not due to the failure of the deoxycytidine phosphorylating activity of the virus induced deoxypyrimidine kinase but to a block in the metabolism of deoxycytidine monophosphate in herpes simplex virus infected cells. This block becomes evident with the appearance of the virus induced deoxypyrimidine kinase activity.
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-31-3-303
The phosphotransferase activity of phosphatases. 1. Spectrophotometric methods for the estimation of some phosphate esters and...The phosphotransferase activity of phosphatases. 1. Spectrophotometric methods for the estimation of some phosphate esters and...
Thank you for your interest in spreading the word about Biochemical Journal.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://www.biochemj.org/content/70/1/134
Search Results
Several hits in gapped BLAST to uridine kinase sequences, e.g. residues 4-206 are 41% similar to the enzyme from B.subtilis (Z99117). UU332 is similar to MG382 and, weakly, to TP0667, two predicted uridine kinases. No similarity to C.trachomatis ...
http://stdgen.northwestern.edu/cgi-bin/gene_id_search.cgi?dbname=uure&gene_id=UU332
Kinase molecule, secondary structure - Stock Image A605/0207 - Science Photo LibraryKinase molecule, secondary structure - Stock Image A605/0207 - Science Photo Library
Kinase molecule, computer model. Kinases, also known as phosphotransferases, are enzymes that catalyse the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP or ADP) to a substrate (such as a protein, lipid or carbohydrate). This process is known as phosphorylation. The largest group of kinases are protein kinases. Up to 518 different types have been identified in humans and are used to transmit signals and control complex processes in cells. In this model the molecules shape (secondary structure) is seen, comprising alpha helices (coils), beta sheets (arrows) and linking regions (lines). - Stock Image A605/0207
http://www.sciencephoto.com/media/6275/view
thiamine-diphosphate kinase(EC 2.7.4.15) - Creative Enzymesthiamine-diphosphate kinase(EC 2.7.4.15) - Creative Enzymes
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor.
https://www.creative-enzymes.com/product/Thiaminediphosphate-Kinase_13365.html
Nemo6 - Structure, Function and Evolution of Nme6/Nm23-H6 Protein - Ruđer Bošković InstituteNemo6 - Structure, Function and Evolution of Nme6/Nm23-H6 Protein - Ruđer Bošković Institute
Nucleoside-diphosphate kinases (Nme/Nm23/NDPK) constitute a family of evolutionary conserved enzymes involved in many crucial biological processes. The...
https://www.irb.hr/eng/Divisions/Division-of-Molecular-Medicine/Laboratory-for-protein-dynamics/Projects/Nemo6-Structure-Function-and-Evolution-of-Nme6-Nm23-H6-Protein
Characterization of glycerol uptake and glycerol kinase activity in rat hepatocytes cultured under different hormonal...Characterization of glycerol uptake and glycerol kinase activity in rat hepatocytes cultured under different hormonal...
Glycerol uptake and glycerol kinase activity were studied in primary cultures of rat hepatocytes in the presence of either 1 nM insulin, 1 nM glucagon, or 100 nM dexamethasone, alone or in combination in
https://www.wizdom.ai/publication/10.1016/S0167-4889
Uridine kinase - WikipediaUridine kinase - Wikipedia
Thus, the two substrates of this enzyme are ATP and uridine, whereas its two products are ADP and UMP. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:uridine 5-phosphotransferase. Other names in common use include pyrimidine ribonucleoside kinase, uridine-cytidine kinase, uridine kinase (phosphorylating), and uridine phosphokinase. This enzyme participates in pyrimidine metabolism. ...
https://en.wikipedia.org/wiki/Uridine_kinase
L-serine-phosphatidylethanolamine phosphatidyltransferase (roundworm) | Protein Target - PubChemL-serine-phosphatidylethanolamine phosphatidyltransferase (roundworm) | Protein Target - PubChem
Protein target information for L-serine-phosphatidylethanolamine phosphatidyltransferase (roundworm). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
https://pubchem.ncbi.nlm.nih.gov/protein/Q09643
CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase)CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase)
CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.
http://atlasgeneticsoncology.org/Genes/GC_CDIPT.html
phosphoinositide-3-kinase regulatory subunit 1 | Phosphatidylinositol kinases | IUPHAR/BPS Guide to PHARMACOLOGYphosphoinositide-3-kinase regulatory subunit 1 | Phosphatidylinositol kinases | IUPHAR/BPS Guide to PHARMACOLOGY
The IUPHAR/BPS Guide to Pharmacology. phosphoinositide-3-kinase regulatory subunit 1 - Phosphatidylinositol kinases. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.
https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2503
The role of the actin cytoskeleton in the regulation of Na+ transport by phosphatidylinositol kinases in the frog skin<...
TY - JOUR. T1 - The role of the actin cytoskeleton in the regulation of Na+ transport by phosphatidylinositol kinases in the frog skin. AU - Krutetskaya, Z. I.. AU - Lebedev, O. E.. AU - Melnitskaya, A. V.. AU - Nozdrachev, A. D.. PY - 2006/10/1. Y1 - 2006/10/1. UR - http://www.scopus.com/inward/record.url?scp=33750374692&partnerID=8YFLogxK. U2 - 10.1134/S001249660605005X. DO - 10.1134/S001249660605005X. M3 - Article. C2 - 17278836. AN - SCOPUS:33750374692. VL - 410. SP - 367. EP - 369. JO - Doklady Biological Sciences. JF - Doklady Biological Sciences. SN - 0012-4966. IS - 1. ER - ...
https://pureportal.spbu.ru/ru/publications/the-role-of-the-actin-cytoskeleton-in-the-regulation-of-na-transp
Binding Stoichiometry of a Recombinant Selenophosphate Synthetase with One Synonymic Substitution E197D to a Fluorescent...Binding Stoichiometry of a Recombinant Selenophosphate Synthetase with One Synonymic Substitution E197D to a Fluorescent...
Journal of Amino Acids is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of amino acids.
https://www.hindawi.com/journals/jaa/2013/983565/
GNPTG (N-acetylglucosamine-1-phosphate transferase subunit gamma)GNPTG (N-acetylglucosamine-1-phosphate transferase subunit gamma)
GNPTG (N-acetylglucosamine-1-phosphate transferase subunit gamma), Authors: Dessen P. Published in: Atlas Genet Cytogenet Oncol Haematol.
http://www.atlasgeneticsoncology.org/Genes/GC_GNPTG.html
Nukleozid-difosfat kinaza - WikipediaNukleozid-difosfat kinaza - Wikipedia
Ratliff, R.L., Weaver, R.H., Lardy, H.A. and Kuby, S.A. (1964). Nucleoside triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). I. Isolation of the crystalline enzyme from brewers yeast. J. Biol. Chem. 239: 301-309. PMID 14114857. ...
https://sh.wikipedia.org/wiki/Nukleozid-difosfat_kinaza
Integral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions. - PubMed - NCBIIntegral membrane lipid phosphatases/phosphotransferases: common structure and diverse functions. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/15801912?dopt=Abstract
Adenilat kinaza - Википедија, слободна енциклопедијаAdenilat kinaza - Википедија, слободна енциклопедија
Saint Girons, I.S., Gilles, A.-M., Margarita, D., Michelson, S., Monnot, M., Fermandjian, S., Danchin, A. and Barzu, O. (1987). „Structural and catalytic characteristics of Escherichia coli adenylate kinase. J. Biol. Chem. 262: 622-629. PMID 3027060 ...
https://sr.wikipedia.org/wiki/Adenilat_kinaza
Human PGS1(CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial) ELISA Kit | Xpress Biotech...Human PGS1(CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial) ELISA Kit | Xpress Biotech...
This item is made to order and will take 10-12 business days to manufacture.Sales on this site ship only to the US and Canada. For other international orders, please email us at [email protected] SKU: XPEH1216 Category: Human ...
https://xpressbio.com/product/human-pgs1cdp-diacylglycerol-glycerol-3-phosphate-3-phosphatidyltransferase-mitochondrial-elisa-kit/
protein-Nπ-phosphohistidine-D-galactose phosphotransferase(EC 2.7.1.204) - Creative Enzymesprotein-Nπ-phosphohistidine-D-galactose phosphotransferase(EC 2.7.1.204) - Creative Enzymes
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found o
https://www.creative-enzymes.com/product/ProteinN-phosphohistidineDgalactose-Phosphotransferase_13208.html
Adenylate Kinase 1抗体- C-terminal|Abcam中国|Anti-Adenylate Kinase 1抗体- C-terminalAdenylate Kinase 1抗体- C-terminal|Abcam中国|Anti-Adenylate Kinase 1抗体- C-terminal
Adenylate Kinase 1兔多克隆抗体(ab71621)可与仓鼠, 人样本反应并经WB, ELISA, IHC实验严格验证。所有产品均提供质保服务，中国75%以上现货。
http://www.abcam.cn/adenylate-kinase-1-antibody-c-terminal-ab71621.html
Adenylate kinase 9Adenylate kinase 9
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIA 1 - 70 AETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLK 71 - 140 PDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 141 - 210 AFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIV 211 - 280 MDRLKYLNLKRAAILTKLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYS 281 - 350 GLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV 351 - 420 DYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEA 421 - 490 THSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKL 491 - 560 YSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYG 561 - 630 GWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKE 631 - 700 EEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 701 - 770 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII 771 - 840 ...
https://pharos.nih.gov/idg/targets/Q5TCS8
Definition for myokinaseDefinition for myokinase
myokinase definition: adenylate kinase, a phosphotransferase chemical that catalyzes the interconversion of adenine nucleotides and plays a crucial role in mobile energy homeostasis.
https://www.azdictionary.com/definition/myokinase
Hereditary erythrocyte adenylate kinase deficiency: A defect of multiple phosphotransferases?<...
TY - JOUR. T1 - Hereditary erythrocyte adenylate kinase deficiency. T2 - A defect of multiple phosphotransferases?. AU - Lachant, N. A.. AU - Zerez, C. R.. AU - Barredo, J.. AU - Lee, D. W.. AU - Savely, S. M.. AU - Tanaka, K. R.. PY - 1991. Y1 - 1991. N2 - Adenylate kinase (AK) modulates the interconversion of adenine nucleotides (AMP + adenosine triphosphate → 2 ADP). We evaluated the fifth kindred with hereditary erythrocyte (RBC) AK deficiency. The proband had chronic hemolytic anemia. Her RBC had undetectable AK activity when measured spectrophotometrically, whereas those of her parents had half-normal AK activity. AK electrophoresis showed only AK-1 in the parents. The activities of pyruvate kinase and phosphoribosylpyrophosphate synthetase were decreased given the young age of the probands RBC. Despite the absence of spectrophotometric AK activity, the probands RBC were able to incorporate 14C-adenine into 14C-adenine nucleotides at 50% of the rate expected for her young RBC ...
https://miami.pure.elsevier.com/en/publications/hereditary-erythrocyte-adenylate-kinase-deficiency-a-defect-of-mu
Hexokinase and glucose-phosphoenolpyruvate phosphotransferase synthesis in Klebsiella aerogenes strains growing in continuous...Hexokinase and glucose-phosphoenolpyruvate phosphotransferase synthesis in Klebsiella aerogenes strains growing in continuous...
Considerable differences in steady-state hexokinase specific activity were found in 16 N.C.I.B. strains of Klebsiella aerogenes grown in identical conditions in glucose-limited chemostats. Strains of N.C.I.B. 8258 had no detectable activity, but its glucose-phosphoenolpyruvate phosphotransferase specific activity and that of the other strains were closely similar, and it is concluded that this phosphotransferase activity regulates the overall utilization of glucose, in which hexokinase plays no essential role. The hexokinase activity was subject to regulation by the availability of phosphorus, but this did not affect the glucose phosphotransferase activity. tlactose-grown organisms (including strain N.C.I.B. 8258) had no glucose phosphotransferase activity, but more than adequate hexokinase activity to phosphorylate the intracellularly liberated glucose. ...
http://www.biochemj.org/content/166/3/643
Phosphoglyceromutase: Definition with Phosphoglyceromutase Pictures and PhotosPhosphoglyceromutase: Definition with Phosphoglyceromutase Pictures and Photos
Definition of Phosphoglyceromutase with photos and pictures, translations, sample usage, and additional links for more information.
http://www.lexic.us/definition-of/phosphoglyceromutase
ADP-Glo Kinase Assay + TGF beta R2 Kinase Enzyme System - MyBio IrelandADP-Glo Kinase Assay + TGF beta R2 Kinase Enzyme System - MyBio Ireland
Overview Protocols Specifications Resources Convenient, Scalable Kinase Profiling The Kinase Enzyme Systems include a recombinant kinase enzyme, a substrate appropriate for the enzyme, a reaction buffer and supplemental reagents as needed. The TGF?R2 Kinase Enzyme System contains: TGF?R2 Kinase, 10ug (Human, recombinan
https://mybio.ie/products/promega-210
ADP-Glo Kinase Assay + p38 gamma Kinase Enzyme System - MyBio IrelandADP-Glo Kinase Assay + p38 gamma Kinase Enzyme System - MyBio Ireland
Overview Protocols Specifications Resources Convenient, Scalable Kinase Profiling The Kinase Enzyme Systems include a recombinant kinase enzyme, a substrate appropriate for the enzyme, a reaction buffer and supplemental reagents as needed. The p38? Kinase Enzyme System contains: p38? Kinase, 10ug (Human, recombinant fu
https://mybio.ie/products/promega-167
Enzyme Commission (EC): Phosphotransferases with a phosphate group as acceptor
Although domain-centric annotations hold great promise in describing phenotypic nature of independent domains, most domains themselves may not just work alone. In multi-domain proteins, they may be combined together to form distinct domain architectures. The recombination of the existing domains is considered as one of major driving forces for phenotypic diversificaation. As an extension, we have also generated supra-domain phenotype ontology and its annotations. Compared to domain-centric phenotype ontology and annotations (SCOP domains at the Superfamily level and Family level), this version focuses on supra-domains and individual SCOP domains ONLY at the Superfamily level. Besides, in terms of individual superfamilies, their annotations from the domain-centric version may be different from those from supra-domains version. Depending on your focus, the former should be used for the consideration of both the Superfamily level and Family level, otherwise the latter should be used if you are ...
https://supfam.org/SUPERFAMILY/cgi-bin/phenotype.cgi?type=EC
ポピュラーベクター Human 遺伝子 GLYCTK (glycerate kinase)
Human (Homo sapiens) のGLYCTK (glycerate kinase)遺伝子を含むベクター、レンチウイルス、アデノウイルス、 (AAV) アデノ随伴、アデノ随伴ウイルス、MMLV レトロウイルス,、piggyBac, shRNA、gRNA、 ガイドRNA、 CRISPR-Cas9 、クリスパー、プラスミド
https://www.vectorbuilder.jp/popular-vectors/human-gene/glyctk-132158.html
KEGG PATHWAY: Phosphotransferase system (PTS) - Bacillus cytotoxicus
The phosphoenolpyruvate (PEP)-dependent phosphotransferase system (PTS) is a major mechanism used by bacteria for uptake of carbohydrates, particularly hexoses, hexitols, and disaccharides, where the source of energy is from PEP. The PTS consists of two general components, enzyme I (EI) and histidine phosphocarrier protein (HPr), and of membrane-bound sugar specific permeases (enzymes II). Each enzyme II (EII) complex consists of one or two hydrophobic integral membrane domains (domains C and D) and two hydrophilic domains (domains A and B). EII complexes may exist as distinct proteins or as a single multidomain protein. The PTS catalyzes the uptake of carbohydrates and their conversion into their respective phosphoesters during transport. There are four successive phosphoryl transfers in the PTS. Initial autophosphorylation of EI, using PEP as a substrate, is followed by transfer of the phosphoryl group from EI to HPr. EIIA catalyzes the self-phosphoryl transfer from HPr after which the ...
http://www.genome.jp/kegg-bin/show_pathway?bcy02060
KEGG PATHWAY: Phosphotransferase system (PTS) - Slackia heliotrinireducens
The phosphoenolpyruvate (PEP)-dependent phosphotransferase system (PTS) is a major mechanism used by bacteria for uptake of carbohydrates, particularly hexoses, hexitols, and disaccharides, where the source of energy is from PEP. The PTS consists of two general components, enzyme I (EI) and histidine phosphocarrier protein (HPr), and of membrane-bound sugar specific permeases (enzymes II). Each enzyme II (EII) complex consists of one or two hydrophobic integral membrane domains (domains C and D) and two hydrophilic domains (domains A and B). EII complexes may exist as distinct proteins or as a single multidomain protein. The PTS catalyzes the uptake of carbohydrates and their conversion into their respective phosphoesters during transport. There are four successive phosphoryl transfers in the PTS. Initial autophosphorylation of EI, using PEP as a substrate, is followed by transfer of the phosphoryl group from EI to HPr. EIIA catalyzes the self-phosphoryl transfer from HPr after which the ...
http://www.genome.jp/kegg-bin/show_pathway?shi02060
Choline kinase - WikipediaCholine kinase - Wikipedia
Choline kinase (also known as CK,ChoK and choline phosphokinase) is an enzyme which catalyzes the first reaction in the choline pathway for phosphatidylcholine (PC) biosynthesis. This reaction involves the transfer of a phosphate group from adenosine triphosphate (ATP) to choline in order to form phosphocholine. ATP + choline ⇌ {\displaystyle \rightleftharpoons } ADP + O-phosphocholine Thus, the two substrates of this enzyme are ATP and choline, whereas its two products are adenosine diphosphate (ADP) and O-phosphocholine. Choline kinase requires magnesium ions (+2) as a cofactor for this reaction. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The first detailed investigation of the enzyme was conducted by McCamen in 1962, where it was shown that the brain is the richest source of the enzyme in mammalian tissue. A related enzyme, ethanolamine kinase, tends to co-purify ...
https://en.wikipedia.org/wiki/Choline_kinase
Browse our Adenylate Kinase 1 ELISA KitsBrowse our Adenylate Kinase 1 ELISA Kits
Order Adenylate Kinase 1 ELISA Kits for many Reactivities. Mouse and more. Compare Adenylate Kinase 1 ELISA Kits and find the right product on antibodies-online.com.
http://www.antibodies-online.com/nucleotide-phosphorylation-pathway-31/adenylate-kinase-1-elisa-kit-8958/
Phosphoserine phosphatasePhosphoserine phosphatase
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008 ...
https://pharos.nih.gov/idg/targets/P78330
DGKQ Kinase Enzyme SystemDGKQ Kinase Enzyme System
Recombinant full-length human DGKQ was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Diacylglycerol kinase theta (DAG kinase theta) is the only member of class V diacylglycerol kinase.
https://www.promega.com/products/cell-signaling/kinase-assays-and-kinase-biology/dgkq-kinase-enzyme-system/?catNum=VA7616
Lichenan-specific phosphotransferase enzyme IIA component elisa and antibodyLichenan-specific phosphotransferase enzyme IIA component elisa and antibody
Shop Lichenan-specific phosphotransferase enzyme IIA component ELISA Kit, Recombinant Protein and Lichenan-specific phosphotransferase enzyme IIA component Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody are available.
https://www.mybiosource.com/protein_family.php?root=lichenan-specific-phosphotransferase-enzyme-iia-component
A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of...
Fingerprint Dive into the research topics of A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels. Together they form a unique fingerprint. ...
https://utsouthwestern.pure.elsevier.com/en/publications/a-mitochondrial-rnai-screen-defines-cellular-bioenergetic-determi/fingerprints/
Regulation of the phosphotransferase system (PTS)
Find the training resources you need for all your activities. Studyres contains millions of educational documents, questions and answers, notes about the course, tutoring questions, cards and course recommendations that will help you learn and learn.
https://studyres.com/doc/17562665/regulation-of-the-phosphotransferase-system--pts-
RCSB PDB for 1AKYRCSB PDB for 1AKY
1AKY: High-resolution structures of adenylate kinase from yeast ligated with inhibitor Ap5A, showing the pathway of phosphoryl transfer.
http://www.rcsb.org/pdb/explore/biologyAndChemistry.do?structureId=1AKY
The increase of adenylate kinase activity in the blood can control aggregation of platelets in coronary or peripheral arterial...The increase of adenylate kinase activity in the blood can control aggregation of platelets in coronary or peripheral arterial...
Activation and aggregation of blood platelets is crucial for hemostasis and thrombosis. In the vascular system adenine nucleotides are important signaling molecules playing a key role in hemostasis. ADP was the first low molecular weight agent recognized to cause blood platelets activation and aggregation. NTPDases and adenylate kinase (AK) are the main enzymes involved in metabolism of extracellular adenine nucleotides. The majority of studies concentrated on the role of NTPDase1 (apyrase) in the inhibition of platelets aggregation. Up to now, there are still insufficient data concerning the role of AK in this process. We found that adenylate kinase activity in the serum of patients with myocardial infarction is significantly increased when compared to the healthy volunteers. The elevated activity of AK is connected to appearance of another isoform of that enzyme, expressed in patients with myocardial infarction. The influence of AK on the pig blood platelets aggregation induced by 20 μM ADP or 7.5
http://www.scirp.org/journal/papercitationdetails.aspx?PaperID=1424&JournalID=65
تحلل السكر - المعرفةتحلل السكر - المعرفة
The energy expenditure of another ATP in this step is justified in 2 ways: The glycolytic process (up to this step) is now irreversible, and the energy supplied destabilizes the molecule. Because the reaction catalyzed by Phosphofructokinase 1 (PFK-1) is coupled to the hydrolysis of ATP, an energetically favorable step, it is, in essence, irreversible, and a different pathway must be used to do the reverse conversion during gluconeogenesis. This makes the reaction a key regulatory point (see below). This is also the rate-limiting step. Furthermore, the second phosphorylation event is necessary to allow the formation of two charged groups (rather than only one) in the subsequent step of glycolysis, ensuring the prevention of free diffusion of substrates out of the cell. The same reaction can also be catalyzed by pyrophosphate-dependent phosphofructokinase (PFP or PPi-PFK), which is found in most plants, some bacteria, archea, and protists, but not in animals. This enzyme uses pyrophosphate (PPi) ...
https://www.marefa.org/index.php/%D8%AA%D8%AD%D9%84%D9%84_%D8%A7%D9%84%D8%B3%D9%83%D8%B1
Broad spectrum aminoglycoside phosphotransferase type III from Enteroc by G. A. McKay, Paul R. Thompson et al.Broad spectrum aminoglycoside phosphotransferase type III from Enteroc by G. A. McKay, Paul R. Thompson et al.
The aminoglycoside phosphotransferases (APHs) are responsible for the bacterial inactivation of many clinically useful aminoglycoside antibiotics. We report the characterization of an enterococcal enzyme, APH(3)-IIIa, which inactivates a broad spectrum of aminoglycosides by ATP-dependent O-phosphorylation. Overproduction of APH(3)-IIIa has permitted the isolation of 30-40 mg of pure protein/(L of cell culture). Purified APH(3)-IIIa is a mixture of monomer and dimer which is slowly converted to dimer only over time. Dimer could be dissociated into monomer by incubation with 2-mercaptoethanol, suggesting that dimerization is mediated by formation of disulfide bond(s). Both monomer and dimer show Km values in the low micromolar range for good substrates such as kanamycin and neomycin, and kcat values of 1-4 s-1. All aminoglycosides show substrate inhibition except amikacin and kanamycin B. Determination of minimum inhibitory concentrations indicates a positive correlation between antibiotic activity and
https://escholarship.umassmed.edu/thompson/99/
Manipulation of pyrophosphate fructose 6-phosphate 1-phosphotransferase activity in sugarcaneManipulation of pyrophosphate fructose 6-phosphate 1-phosphotransferase activity in sugarcane
The main aim of the work presented in this thesis was to elucidate the apparent role of pyrophosphate fructose 6-phosphate 1-phosphotransferase (PFP) in sucrose accumulation in sugarcane. PFP activity in sugarcane internodal tissue is inversely correlated to the sucrose content and positively to the water-insoluble component across varieties which differ in their capacities to accumulate sucrose. This apparent well defined and important role of PFP seems to stand in contrast to the ambiguity regarding PFPs role in the general literature as well as the results of various transgenic studies where neither the downregulation nor the over-expression of PFP activity had a major influence on the phenotype of transgenic potato and tobacco plants. Based on this it was therefore thought that either the kinetic properties of sugarcane PFP is significantly different than that of other plant PFPs or that PFPs role in sucrose accumulating tissues is different from that in starch accumulating tissues. In the ...
http://scholar.sun.ac.za/handle/10019.1/1089
Human Metabolome Database: Showing Protein CDP-diacylglycerol--inositol 3-phosphatidyltransferase (HMDBP00771)Human Metabolome Database: Showing Protein CDP-diacylglycerol--inositol 3-phosphatidyltransferase (HMDBP00771)
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, ...
https://hmdb.ca/proteins/HMDBP00771
Light-Regulated Alternative Splicing of Pseudo-Histidine Phosphotransfer Protein 3 in Oryza sativa | SpringerLinkLight-Regulated Alternative Splicing of Pseudo-Histidine Phosphotransfer Protein 3 in Oryza sativa | SpringerLink
The two-component system is involved in several developmental events and different responses to the environment. Histidine-containing phosphotransfer prote
https://link.springer.com/article/10.1007/s00344-019-09927-8?error=cookies_not_supported&code=a7850c26-c350-4dd3-a3ed-2efa12e547cf
High-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymesHigh-energy phosphotransfer in the failing mouse heart: role of adenylate kinase and glycolytic enzymes
AimsTo measure the activity of the key phosphotransfer enzymes creatine kinase (CK), adenylate kinase (AK), and glycolytic enzymes in two common mouse models of chronic heart failure.Methods and resultsC57BL/6 mice were subjected to transverse aortic constriction (TAC), myocardial infarction induced
https://insights.ovid.com/european-heart-failure/ejhf/2010/12/000/high-energy-phosphotransfer-failing-mouse-heart/5/00127070
Structure Cluster - 1BIF: 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE BIFUNCTIONAL ENZYME COMPLEXED WITH ATP...Structure Cluster - 1BIF: 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE BIFUNCTIONAL ENZYME COMPLEXED WITH ATP...
1BIF: The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies.
http://www.rcsb.org/pdb/explore/structureCluster.do?structureId=1BIF
Bisphosphoglycerate mutase antibody | acris-antibodies.com
Kit Component:- KN302227G1, Bpgm gRNA vector 1 in pCas-Guide vector- KN302227G2, Bpgm gRNA vector 2 in pCas-Guide vector- KN302227D, donor vector…
https://www.acris-antibodies.com/target/bisphosphoglycerate-mutase-antibody.htm
Search Results
Numerous significant hits using gapped BLAST to aspartokinase III from E. coli (416597), Arabidopsis thaliana (6091740, putative), Methanococcus jannaschii (2492982), among others. HD1375 is 57% similar to residues 1-449 from AK3_ECOLI ...
http://stdgen.northwestern.edu/cgi-bin/gene_id_search.cgi?dbname=hduc&gene_id=HD1375
Feature search
Similar to Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 3 (Dictyostelium discoideum) (uniprot_sprot:sp,Q550W1,CAPTC_DICDI ...
http://melonomics.cragenomica.es/search/features/?go_term=nuclear%20envelope&kind=protein_coding_gene
EGFR (d746) Kinase Enzyme SystemEGFR (d746) Kinase Enzyme System
Recombinant human EGFR (d746) (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.
https://www.promega.com/products/cell-signaling/kinase-assays-and-kinase-biology/egfr-d746-kinase-enzyme-system/
P-POD: Princeton Protein Orthology Database
tRNA 2-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1-2cyclic phosphate and ...
http://ppod.princeton.edu/cgi-bin/ppod.cgi?an=2&s=S000005462
Therapeutics: anticancer agent: alpelisibTherapeutics: anticancer agent: alpelisib
Phosphoinositide 3-kinase enzymes are a group of intracellular signal transducers that phosphorylate the 3-hydroxyl group of phosphatidylinositol
https://www.manufacturingchemist.com/news/article_page/Therapeutics_anticancer_agent_alpelisib/151713
Plain bearing block - 406-001-18 - Seldén Mast AB - cam cleat / cheek / flatPlain bearing block - 406-001-18 - Seldén Mast AB - cam cleat / cheek / flat
Find out all of the information about the Seldén Mast AB product: plain bearing block 406-001-18. Contact a supplier or the parent company directly to get a quote or to find out a price or your closest point of sale.
https://www.nauticexpo.com/prod/selden-mast-ab/product-21696-221391.html
Aucho ndani Yanga, aikacha Simba - MwananchiAucho ndani Yanga, aikacha Simba - Mwananchi
YANGA imeendelea kusuka mipango yao ya kuchukua mataji msimu ujao na sasa wako katika mazungumzo ya mwisho kabisa kumleta kiungo mwingine wa kazi, Mganda Khalid Aucho.
https://www.mwananchi.co.tz/mw/michezo/aucho-ndani-yanga-aikacha-simba-3497106
Kanamycin kinaseKanamycin kinase
Aminoglycoside-3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the ... The systematic name of this enzyme class is ATP:kanamycin 3'-O-phosphotransferase. This enzyme is also called neomycin- ... Fong, DH, Berghuis, AM (2002). "Crystal Structure Of 3',5"-Aminoglycoside Phosphotransferase Type IIIa ADP Kanamycin A Complex ... McKay, GA, Thompson, PR, Wright, GD (1994). "Broad spectrum aminoglycoside phosphotransferase type III from Enterococcus: ...
https://en.wikipedia.org/wiki/Kanamycin_kinase
Adenylate kinaseAdenylate kinase
There is a mitochondrial GTP:AMP phosphotransferase, also specific for the phosphorylation of AMP, that can only use GTP or ITP ... Adenylate kinase (EC 2.7.4.3) (also known as ADK or myokinase) is a phosphotransferase enzyme that catalyzes the ... Tomasselli AG, Noda LH (January 1979). "Mitochondrial GTP-AMP phosphotransferase. 2. Kinetic and equilibrium dialysis studies ...
https://en.wikipedia.org/wiki/Adenylate_kinase
Ammonia kinaseAmmonia kinase
The systematic name of this enzyme class is ATP:ammonia phosphotransferase. Other names in common use include phosphoramidate- ... adenosine diphosphate phosphotransferase, and phosphoramidate-ADP-phosphotransferase. Dowler MJ, Nakada HI (1968). "Yeast ... phosphoramidate-adenosine diphosphate phosphotransferase". J. Biol. Chem. 243 (7): 1434-40. PMID 5647264. Portal: Biology v t e ... phosphotransferases) with a nitrogenous group as acceptor. ...
https://en.wikipedia.org/wiki/Ammonia_kinase
KinaseKinase
... s are part of the larger family of phosphotransferases. Kinases should not be confused with phosphorylases, which ... kinase Phosphatase Phosphatidylinositol phosphate kinases Phospholipid Phosphoprotein Phosphorylation Phosphotransferase Signal ...
https://en.wikipedia.org/wiki/Kinase
DikinaseDikinase
Their designated EC number is 2.7.9. It is one of the smallest groups of phosphotransferases. Dikinases take two phosphate ... Dikinases should not be confused with diphosphotransferases (EC 2.7.6), which are phosphotransferases which act upon ...
https://en.wikipedia.org/wiki/Dikinase
Guanidinoacetate kinaseGuanidinoacetate kinase
The systematic name of this enzyme class is ATP:guanidinoacetate N-phosphotransferase. This enzyme is also called glycocyamine ... Pradel LA, Kassab R, Thoai NV (1964). "Sur l'acide adenosine-triphosphorique:guanidoacetate phosphotransferase". Biochim. ... guanidinoacetate phosphotransferase]". Biochim. Biophys. Acta. 154 (2): 305-14. doi:10.1016/0005-2795(68)90044-5. PMID 5637051 ... phosphotransferases) with a nitrogenous group as acceptor. ...
https://en.wikipedia.org/wiki/Guanidinoacetate_kinase
MannoseMannose
Erni, B.; Zanolari, B. (1985). "The mannose-permease of the bacterial phosphotransferase system. Gene cloning and purification ... Huang, Kai; Zeng, Jianwei; Liu, Xueli; Jiang, Tianyu; Wang, Jiawei (2021-04-06). "Structure of the mannose phosphotransferase ... Postma, P. W.; Lengeler, J. W.; Jacobson, G. R. (1993). "Phosphoenolpyruvate:carbohydrate phosphotransferase systems of ... "Structure of the mannose transporter of the bacterial phosphotransferase system". Cell Research. 29 (8): 680-682. doi:10.1038/ ...
https://en.wikipedia.org/wiki/Mannose
Phosphocarrier proteinPhosphocarrier protein
Meadow ND, Fox DK, Roseman S (1990). "The bacterial phosphoenolpyruvate: glycose phosphotransferase system". Annu. Rev. Biochem ... Postma PW, Lengeler JW, Jacobson GR (1993). "Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria". ... The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) is a major carbohydrate transport system in bacteria. ... HPr protein is a small cytoplasmic protein that is a component of the phosphoenolpyruvate-dependent sugar phosphotransferase ...
https://en.wikipedia.org/wiki/Phosphocarrier_protein
GlycolysisGlycolysis
Reeves RE, South DJ, Blytt HJ, Warren LG (December 1974). "Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new ... August 2017). "The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism ...
https://en.wikipedia.org/wiki/Glycolysis
Choline kinaseCholine kinase
The systematic name of this enzyme class is ATP:choline phosphotransferase. These enzymes participate in glycine, serine and ... McKay GA, Wright GD (October 1995). "Kinetic mechanism of aminoglycoside phosphotransferase type IIIa. Evidence for a Theorell- ... phosphotransferases) with an alcohol group as acceptor. The first detailed investigation of the enzyme was conducted by McCamen ... an aminoglycoside phosphotransferase and CK.[citation needed] Propositions for this mechanism have been made based on ...
https://en.wikipedia.org/wiki/Choline_kinase
PTS L-Ascorbate FamilyPTS L-Ascorbate Family
"The complete phosphotransferase system in Escherichia coli". Journal of Molecular Microbiology and Biotechnology. 3 (3): 329-46 ...
https://en.wikipedia.org/wiki/PTS_L-Ascorbate_Family
ValganciclovirValganciclovir
The phosphotransferase enzyme can likewise activate valganciclovir. The synthesis of valganciclovir has been reviewed. Many ...
https://en.wikipedia.org/wiki/Valganciclovir
PEP group translocationPEP group translocation
With the glucose phosphotransferase system, the phosphorylation status of EIIA can have regulatory functions. For example, at ... The phosphotransferase system is involved in transporting many sugars into bacteria, including glucose, mannose, fructose and ... PEP group translocation, also known as the phosphotransferase system or PTS, is a distinct method used by bacteria for sugar ... The HPr is common to the phosphotransferase systems of the other substrates mentioned earlier, as is the upstream EI. Proteins ...
https://en.wikipedia.org/wiki/PEP_group_translocation
PTS Galactitol FamilyPTS Galactitol Family
Tchieu, J. H.; Norris, V.; Edwards, J. S.; Saier, M. H. (2001-07-01). "The complete phosphotransferase system in Escherichia ... Reizer, Jonathan (Apr 1995). "Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster ...
https://en.wikipedia.org/wiki/PTS_Galactitol_Family
PFP (enzyme)PFP (enzyme)
... and pyrophosphate-fructose 6-phosphate 1-phosphotransferase, pyrophosphate-fructose 6-phosphate phosphotransferase PFK PDB: ... The systematic name of this enzyme class is diphosphate:D-fructose-6-phosphate 1-phosphotransferase. Other names in common use ... Diphosphate-fructose-6-phosphate 1-phosphotransferase also known as PFP is an enzyme of carbohydrate metabolism in plants and ... Reeves RE, South DJ, Blytt HJ, Warren LG (December 1974). "Pyrophosphate:D-fructose 6-phosphate 1-phosphotransferase. A new ...
https://en.wikipedia.org/wiki/PFP_(enzyme)
Aigialomycin DAigialomycin D
Advances in Phosphotransferases (Alcohol Group Acceptor) Research and Application: 2012 Edition. ScholarlyEditions. 26 December ...
https://en.wikipedia.org/wiki/Aigialomycin_D
Streptomyces venezuelaeStreptomyces venezuelae
Chloramphenicol phosphotransferase-like protein family "Species Streptomyces venezuelae". UniProt. 2008-07-22. Retrieved 2008- ...
https://en.wikipedia.org/wiki/Streptomyces_venezuelae
AMP-thymidine kinaseAMP-thymidine kinase
The systematic name of this enzyme class is AMP:thymidine 5'-phosphotransferase. This enzyme is also called adenylate- ... Falke D, Labenz J, Brauer D, Muller WE (1982). "Adenosine diphosphate: thymidine 5'-phosphotransferase, a new enzyme activity, ... Falke D, Nehrbass W, Brauer D, Muller WE (1981). "Adenylic acid: deoxythymidine 5'-phosphotransferase: evidence for the ... phosphotransferases) with an alcohol group as acceptor. ...
https://en.wikipedia.org/wiki/AMP—thymidine_kinase
Acetate kinase (diphosphate)Acetate kinase (diphosphate)
The systematic name of this enzyme class is diphosphate:acetate phosphotransferase. This enzyme is also called pyrophosphate- ... acetate phosphotransferase. This enzyme participates in pyruvate metabolism. Reeves RE, Guthrie JD (1975). "Acetate kinase ( ... phosphotransferases) with a carboxy group as acceptor. ...
https://en.wikipedia.org/wiki/Acetate_kinase_(diphosphate)
Phosphoglucomutase (glucose-cofactor)Phosphoglucomutase (glucose-cofactor)
FUJIMOTO A, INGRAM P, SMITH RA (1965). "D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6-PHOSPHOTRANSFERASE". Biochim. Biophys. Acta. 96: 91- ... This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer ... and glucose-1-phosphate phosphotransferase. This enzyme has at least one effector, D-Glucose. ...
https://en.wikipedia.org/wiki/Phosphoglucomutase_(glucose-cofactor)
Zeta toxin protein domainZeta toxin protein domain
The Zeta Toxin is folded like a phosphotransferase. This domain features an α/β structure and the central twisted β-sheet ...
https://en.wikipedia.org/wiki/Zeta_toxin_protein_domain
Hygromycin-B kinaseHygromycin-B kinase
The systematic name of this enzyme class is ATP:hygromycin-B 7"-O-phosphotransferase. This enzyme is also called hygromycin B ... Zalacain M, Pardo JM, Jimenez A (1987). "Purification and characterization of a hygromycin B phosphotransferase from ... phosphotransferases) with an alcohol group as acceptor. ...
https://en.wikipedia.org/wiki/Hygromycin-B_kinase
Lombricine kinaseLombricine kinase
The systematic name of this enzyme class is ATP:lombricine N-phosphotransferase. This enzyme participates in glycine, serine ... Kassab R; Pradel LA; Nguyen Van Thoai (1965). "[ATP:taurocyamine and ATP:lombricine phosphotransferases Purification and study ... "The purification and properties of adenosine triphosphate-lombricine phosphotransferase". Biochem. J. 90 (1): 170-6. PMC ... phosphotransferases) with a nitrogenous group as acceptor. ...
https://en.wikipedia.org/wiki/Lombricine_kinase
Taurocyamine kinaseTaurocyamine kinase
Other names in common use include taurocyamine phosphotransferase, and ATP:taurocyamine phosphotransferase. This enzyme ... Kassab R, Pradel LA, Nguyen VT (1965). "[ATP:taurocyamine and ATP:lombricine phosphotransferases Purification and study of SH ... The systematic name of this enzyme class is ATP:taurocyamine N-phosphotransferase. ... phosphotransferases) with a nitrogenous group as acceptor. ...
https://en.wikipedia.org/wiki/Taurocyamine_kinase
Marinitoga piezophilaMarinitoga piezophila
Advances in Phosphotransferases (Phosphate Group Acceptor) Research and Application: 2013 Edition: ScholarlyPaper. ...
https://en.wikipedia.org/wiki/Marinitoga_piezophila
Samson WrightSamson Wright
... phosphotransferase system (PTS) proteins". Philosophical Transactions of the Royal Society of London. Series B, Biological ...
https://en.wikipedia.org/wiki/Samson_Wright
Saul RosemanSaul Roseman
I. Isolation of a phosphotransferase system from Escherichia coli. J Biol Chem 246:1393-1406. Book of Members 1780-Present (PDF ... Among many discoveries related to carbohydrate biochemistry, he discovered the phosphotransferase system in bacteria. 1971 ...
https://en.wikipedia.org/wiki/Saul_Roseman
DiphosphotransferaseDiphosphotransferase
... are phosphotransferase enzymes which act upon pyrophosphate groups. They are classified under EC number ...
https://en.wikipedia.org/wiki/Diphosphotransferase
MethanosarcinaMethanosarcina
... a member of the ASKHA superfamily of phosphotransferases". Journal of Bacteriology. 183 (2): 680-686. doi:10.1128/JB.183.2.680- ...
https://en.wikipedia.org/wiki/Methanosarcina
PSPHPSPH
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the ... Collet JF, Stroobant V, Pirard M, Delpierre G, Van Schaftingen E (Jun 1998). "A new class of phosphotransferases phosphorylated ...
https://en.wikipedia.org/wiki/PSPH
RCSB PDB - 1XIZ: Structural Genomics, The crystal structure of domain IIA of putative phosphotransferase system specific for...RCSB PDB - 1XIZ: Structural Genomics, The crystal structure of domain IIA of putative phosphotransferase system specific for...
The crystal structure of domain IIA of putative phosphotransferase system specific for mannitol/fructose from Salmonella ... putative phosphotransferase system mannitol/fructose-specific IIA domain. A, B. 159. Salmonella enterica subsp. enterica ... Structural Genomics, The crystal structure of domain IIA of putative phosphotransferase system specific for mannitol/fructose ... The crystal structure of domain IIA of putative phosphotransferase system specific for mannitol/fructose from Salmonella ...
https://www.rcsb.org/structure/1XIZ
ROLE OF THE PHOSPHOENOLPYRUVATE: CARBOHYDRATE PHOSPHOTRANSFERASE SYSTEM IN THE VIRULENCE OF THE GROUP A STREPTOCOCCUSROLE OF THE PHOSPHOENOLPYRUVATE: CARBOHYDRATE PHOSPHOTRANSFERASE SYSTEM IN THE VIRULENCE OF THE GROUP A STREPTOCOCCUS
... ... The Phosphoenolpyruvate Phosphotransferase System (PTS) is a primary mechanism by which many bacteria transport sugars and ...
https://drum.lib.umd.edu/handle/1903/15301
EN (en)EN (en)
Structural relationship between the genes encoding 3′-aminoglycoside phosphotransferases in Campylobacter and in gram-positive ... aminoglycoside phosphotransferase of type III (APH(3′)-III), an enzyme so far confined to Gram-positive cocci. The kanamycin ...
https://research.pasteur.fr/en/publication/structural-relationship-between-the-genes-encoding-3-aminoglycoside-phosphotransferases-in-campylobacter-and-in-gram-positive-cocci/
Evidence of a New MoYpd1p Phosphotransferase Isoform in the Multistep Phosphorelay System of Magnaporthe oryzae[v1] | PreprintsEvidence of a New MoYpd1p Phosphotransferase Isoform in the Multistep Phosphorelay System of Magnaporthe oryzae[v1] | Preprints
Evidence of a New MoYpd1p Phosphotransferase Isoform in the Multistep Phosphorelay System of Magnaporthe oryzae. Sri Bühring ... Bühring, B.; Yemelin, A.; Michna, T.; Tenzer, S.; Jacob, S. Evidence of a New MoYpd1p Phosphotransferase Isoform in the ... Bühring, B.; Yemelin, A.; Michna, T.; Tenzer, S.; Jacob, S. Evidence of a New MoYpd1p Phosphotransferase Isoform in the ... Bühring, B.; Yemelin, A.; Michna, T.; Tenzer, S.; Jacob, S. Evidence of a New MoYpd1p Phosphotransferase Isoform in the ...
https://www.preprints.org/manuscript/202104.0291/v1
KOPS.Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und GlucokinaseKOPS.Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und Glucokinase
Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und Glucokinase. Type of Publication:. Dissertation. ... Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und Glucokinase [Dissertation]. Konstanz: University of ... phdthesis{Witte2015Regul-31669, title={Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und Glucokinase}, year ... Regulation des bakteriellen Phosphotransferase-Systems durch Mlc und Glucokinase,/dcterms:title, ,dc:contributor,Witte, David ...
https://kops.uni-konstanz.de/handle/123456789/31669
Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase
Molecular analysis of the GlcNac-1-phosphotransferase.. Braulke T, Pohl S, Storch S., J Inherit Metab Dis 31(2), 2008 PMID: ... Role of spacer-1 in the maturation and function of GlcNAc-1-phosphotransferase.. Liu L, Lee WS, Doray B, Kornfeld S., FEBS Lett ... N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (UNIPROT: Q3T906). Organism: Homo sapiens. Download in FASTA ... Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase. Tiede S, Storch S, Lübke ...
https://pub.uni-bielefeld.de/record/1940057
Phosphotransferases (Carboxyl Group Acceptor) | Profiles RNS
"Phosphotransferases (Carboxyl Group Acceptor)" is a descriptor in the National Library of Medicines controlled vocabulary ... This graph shows the total number of publications written about "Phosphotransferases (Carboxyl Group Acceptor)" by people in ... Below are the most recent publications written about "Phosphotransferases (Carboxyl Group Acceptor)" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Phosphotransferases (Carboxyl Group Acceptor)". ...
https://researchers.childrensmercy.org/display/19400
Sugar influx sensing by the phosphotransferase system of Escherichia coli | Max-Planck-Institut für terrestrische MikrobiologieSugar influx sensing by the phosphotransferase system of Escherichia coli | Max-Planck-Institut für terrestrische Mikrobiologie
Sugar influx sensing by the phosphotransferase system of Escherichia coli. Graduate Students Mini-Symposium. ...
https://www.mpi-marburg.mpg.de/events/5042/130871
GNPTG gene: MedlinePlus GeneticsGNPTG gene: MedlinePlus Genetics
... of an enzyme called GlcNAc-1-phosphotransferase. Learn about this gene and related health conditions. ... GlcNAc-1-phosphotransferase is involved in the first step of making a molecule called mannose-6-phosphate (M6P). M6P acts as a ... Specifically, GlcNAc-1-phosphotransferase transfers a molecule called GlcNac-1-phosphate to a newly produced hydrolase. In the ... The GNPTG gene provides instructions for making one part, the gamma subunit, of an enzyme called GlcNAc-1-phosphotransferase. ...
https://medlineplus.gov/genetics/gene/gnptg/
Table 3 - Description and Nomenclature of Neisseria meningitidis Capsule Locus - Volume 19, Number 4-April 2013 - Emerging...
Putative phosphotransferase with licD domain (involved in phosphorylcholine decoration of teichoic acid). 1,269. 33. ... Putative phosphotransferase with licD domain (involved in phosphorylcholine decoration of teichoic acid). 1,290. 45. ...
https://wwwnc.cdc.gov/eid/article/19/4/11-1799-t3.htm
IMSEAR at SEARO: Diverse aminoglycoside phosphotransferase types conferring aminoglycoside resistance in Enterobacteriaceae: A...
Diverse aminoglycoside phosphotransferase types conferring aminoglycoside resistance in Enterobacteriaceae: A single-centre ... Diverse aminoglycoside phosphotransferase types conferring aminoglycoside resistance in Enterobacteriaceae: A single-centre ...
https://imsear.searo.who.int/handle/123456789/198895
Sugar influx sensing by the phosphotransferase system of Escherichia coli :: MPG.PuReSugar influx sensing by the phosphotransferase system of Escherichia coli :: MPG.PuRe
Sugar influx sensing by the phosphotransferase system of Escherichia coli ... Sugar influx sensing by the phosphotransferase system of Escherichia coli Somavanshi, R. (2016). Sugar influx sensing by the ...
https://pure.mpg.de/pubman/faces/ViewItemFullPage.jsp?itemId=item_3271391_1&view=EXPORT
Interaction of Neisseria meningitidis group X N-acetylglucosamine-1-phosphotransferase with its donor substrate
... dc.rights. ... We have demonstrated previously that the formation of the polymer is catalyzed by a phosphotransferase which transfers N- ... Our kinetic analysis of the phosphotransferase reaction is consistent with a sequential mechanism of substrate addition and ... Interaction of Neisseria meningitidis group X N-acetylglucosamine-1-phosphotransferase with its donor substrate, S. Ming, E. ...
https://dspace.rpi.edu/handle/20.500.13015/5019?show=full
Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli. | Profiles RNS
Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli. Antimicrob Agents ... Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli.. ...
https://profiles.uchicago.edu/profiles/display/8601873
Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndromeMutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemia D and periodic fever syndrome
Phosphotransferases (Alcohol Group Acceptor) / biosynthesis * Phosphotransferases (Alcohol Group Acceptor) / genetics* * Point ...
https://pubmed.ncbi.nlm.nih.gov/10369261/?dopt=Abstract
Homoserine kinase - WikipediaHomoserine kinase - Wikipedia
The systematic name of this enzyme class is ATP:L-homoserine O-phosphotransferase. Other names in common use include homoserine ... phosphotransferases) with an alcohol group as acceptor. ...
https://en.wikipedia.org/wiki/Homoserine_kinase
Advanced Search Results - Public Health Image Library(PHIL)Advanced Search Results - Public Health Image Library(PHIL)
Categories: Phosphotransferases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted ...
https://phil.cdc.gov/AdvancedSearchResults.aspx?Search=Phosphotransferases&parentid=26072&catid=20113
PDB 3SGC | Chain CRYSTAL STRUCTURE OF APO AMINOGLYCOSIDE-2-PHOSPHOTRANSFERASE TYPE IVA | 3SGC A | 3D Structure | CancerPDB 3SGC | Chain CRYSTAL STRUCTURE OF APO AMINOGLYCOSIDE-2''-PHOSPHOTRANSFERASE TYPE IVA | 3SGC A | 3D Structure | Cancer
3D Structure of chain 3SGC_A - CRYSTAL STRUCTURE OF APO AMINOGLYCOSIDE-2-PHOSPHOTRANSFERASE TYPE IVA - 3SGC , canSAR.ai
https://cansar.ai/structure/3SGC/3d/3SGC_A
Issue: Molecular CellIssue: Molecular Cell
A Combined Approach Reveals a Regulatory Mechanism Coupling Srcs Kinase Activity, Localization, and Phosphotransferase- ...
https://www.cell.com/molecular-cell/issue?pii=S1097-2765%2818%29X0009-4
Consensus pan-genome assembly of the specialised wine bacterium Oenococcus oeni | BMC Genomics | Full TextConsensus pan-genome assembly of the specialised wine bacterium Oenococcus oeni | BMC Genomics | Full Text
Phosphotransferase enzyme systems in fGIs. The range of sugars that O. oeni is capable of utilising is strain dependent [46]. ... 4b). Four phosphotransferases, containing all of the required subunits, were conserved in the majority of strains: mannose- ... Two phosphotransferases were observed to correspond to specific clades: the fructose-specific II and ascorbate-specific II. The ... In addition to these differences, two highly strain-specific phosphotransferases were observed: sucrose-specific II and lactose ...
https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2604-7
NT5C3A 5-nucleotidase, cytosolic IIIA [Homo sapiens (human)] - Gene - NCBINT5C3A 5'-nucleotidase, cytosolic IIIA [Homo sapiens (human)] - Gene - NCBI
enables tRNA 2-phosphotransferase activity NAS Non-traceable Author Statement. more info ...
https://www.ncbi.nlm.nih.gov/gene/51251
Osmium in PDB 1rmq: Crystal Structure of Apha Class B Acid Phosphatase/Phosphotransferase with Osmiate Mimicking the Catalytic...
Crystal Structure of Apha Class B Acid Phosphatase/Phosphotransferase with Osmiate Mimicking the Catalytic Intermediate ... The structure of Crystal Structure of Apha Class B Acid Phosphatase/Phosphotransferase with Osmiate Mimicking the Catalytic ... The binding sites of Osmium atom in the Crystal Structure of Apha Class B Acid Phosphatase/Phosphotransferase with Osmiate ... Osmium binding site 1 out of 4 in the Crystal Structure of Apha Class B Acid Phosphatase/Phosphotransferase with Osmiate ...
http://osmium.atomistry.com/pdb1rmq.html
Metabolites | Free Full-Text | Modelling hCDKL5 Heterologous Expression in BacteriaMetabolites | Free Full-Text | Modelling hCDKL5 Heterologous Expression in Bacteria
ATPL-aspartate 4-phosphotransferase. ATP + l-aspartate =, ADP + 4-phospho-l-aspartate. ... catalysed by ATPL-aspartate-4-phosphotransferase and l-aspartate-4-semialdehyde: NADP + oxidoreductase, respectively. l- ...
https://www.mdpi.com/2218-1989/11/8/491
Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH (3 ″)-Id from...Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH (3 ″)-Id from...
To evaluate the phosphotransferase activity of the recombinant protein APH(3″)-Id we carried out thin-layer chromatography of ... Here are the kinetic parameters of the streptomycin phosphotransferase APH(3″)-Id: Km 80.4 μM, Vmax 6.45 μmol/min/mg and kcat ... In this study, we identified a new gene (aph(3″)-Id) coding for a streptomycin phosphotransferase by using phylogenetic ... Comparison of the obtained structures with those of other aminoglycoside phosphotransferases revealed peculiar structure of the ...
https://www.bioinfor.com/identification-functional-structural-characterization-novel-aminoglycoside-phosphotransferase-aph-3-%E2%80%B3-id-streptomyces-rimosus-subsp-rimosus-atcc-10970/
Recovery of the Peptidoglycan Turnover Product Released by the Autolysin Atl in Staphylococcus aureus Involves the...Recovery of the Peptidoglycan Turnover Product Released by the Autolysin Atl in Staphylococcus aureus Involves the...
... of the Peptidoglycan Turnover Product Released by the Autolysin Atl in Staphylococcus aureus Involves the Phosphotransferase ... of the Peptidoglycan Turnover Product Released by the Autolysin Atl in Staphylococcus aureus Involves the Phosphotransferase ...
https://publikationen.uni-tuebingen.de/xmlui/handle/10900/89855
CN104059927A - Preparation method of newcastle disease glucoprotein virus antigen and product thereof - Google Patents
108091000081 Phosphotransferases Proteins 0.000 claims description 2 * 229960000856 Protein C Drugs 0.000 claims description 2 ...
https://patents.google.com/patent/CN104059927A/en
RM3-3| GM Approval Database- ISAAA.org
neomycin phosphotransferase II enzyme. allows transformed plants to metabolize neomycin and kanamycin antibiotics during ...
https://www.isaaa.org/gmapprovaldatabase/event/default.asp?EventID=39
WO1999029894 FLUORESCENCE-BASED HIGH THROUGHPUT SCREENING ASSAYS FOR PROTEIN KINASES AND PHOSPHATASESWO1999029894 FLUORESCENCE-BASED HIGH THROUGHPUT SCREENING ASSAYS FOR PROTEIN KINASES AND PHOSPHATASES
Phosphotransferases in general. 9121. with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine ... Phosphotransferases in general. 9121. with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine ...
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO1999029894
Phosphatidylinositol-4-Phosphate 3-Kinase | Harvard Catalyst Profiles | Harvard CatalystPhosphatidylinositol-4-Phosphate 3-Kinase | Harvard Catalyst Profiles | Harvard Catalyst
Phosphotransferases [D08.811.913.696]. *Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]. * ...
https://connects.catalyst.harvard.edu/Profiles/display/Concept/Phosphatidylinositol-4-Phosphate%203-Kinase
KinasesAminoglycoside phosphotransferaseAcceptorEscherichiaKinaseEnzymePutativeSubunitsEnzymesAssaysGeneKineticTransfersActivityMutationsSystemCrystal structureKinaseBacterial phosphotransferase systemNeomycinPhosphoenolpyruvate-dependent sugar phosphotransferase systemGenesParalogous Phosphotransferase SystemsProteinsTransport to lysosomesMucolipidosis typeResistanceGNPTABMoleculeDescriptor
Kinases1
  • The MAPKK subfamily is part of a larger superfamily that includes the catalytic domains of other protein serine/threonine kinases, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase. (umbc.edu)
Aminoglycoside phosphotransferase4
  • Phosphocellulose paper-binding assay indicated that resistance to kanamycin and structurally related antibiotics in strain BM2509 was due to synthesis of a 3′-aminoglycoside phosphotransferase of type III (APH(3′)-III), an enzyme so far confined to Gram-positive cocci. (pasteur.fr)
  • Wangkheimayum J, Bhattacharjee M, Das BJ, Singha K M, Chanda DD, Chanda DD, Bhowmik D, Bhattacharjee A. Diverse aminoglycoside phosphotransferase types conferring aminoglycoside resistance in Enterobacteriaceae: A single-centre study from Northeast India. (who.int)
  • Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli. (uchicago.edu)
  • Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH (3 ″)-Id from Streptomyces rimosus subsp. (bioinfor.com)
Acceptor4
  • Phosphotransferases (Carboxyl Group Acceptor)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
  • This graph shows the total number of publications written about "Phosphotransferases (Carboxyl Group Acceptor)" by people in this website by year, and whether "Phosphotransferases (Carboxyl Group Acceptor)" was a major or minor topic of these publications. (childrensmercy.org)
  • Below are the most recent publications written about "Phosphotransferases (Carboxyl Group Acceptor)" by people in Profiles. (childrensmercy.org)
  • This enzyme belongs to the family of transferases , specifically those transferring phosphorus-containing groups ( phosphotransferases ) with an alcohol group as acceptor. (wikipedia.org)
Escherichia1
  • The kanamycin and tetracycline resistances were transferable en bloc by conjugation to C. fetus but not to Escherichia coli. (pasteur.fr)
Kinase1
  • In contrast to standard assays which rely on antibody detection of a phosphoepitope or monitoring ATP depletion as the result of kinase activity, these assays are gain-of-signal assays that generate a positive readout in direct proportion to ADP accumulation, which results from phosphotransferase activity. (discoverx.com)
Enzyme2
  • The GNPTG gene provides instructions for making one part, the gamma subunit, of an enzyme called GlcNAc-1-phosphotransferase. (medlineplus.gov)
  • The systematic name of this enzyme class is ATP:L-homoserine O-phosphotransferase . (wikipedia.org)
Putative1
  • To evaluate the phosphotransferase activity of the recombinant protein APH(3″)-Id we carried out thin-layer chromatography of the putative 32P-labeled streptomycin phosphate. (bioinfor.com)
Subunits1
  • Pohl S, Tiede S, Castrichini M, Cantz M, Gieselmann V, Braulke T. Compensatory expression of human N-acetylglucosaminyl-1-phosphotransferase subunits in mucolipidosis type III gamma. (medlineplus.gov)
Enzymes1
  • GlcNAc-1-phosphotransferase helps prepare certain newly made enzymes for transport to lysosomes. (medlineplus.gov)
Assays1
  • Activity-based ADP accumulation assays are generic, antibody-free, and homogeneous - ideal for identifying and characterizing phosphotransferase activity. (discoverx.com)
Gene1
  • In this study, we identified a new gene (aph(3″)-Id) coding for a streptomycin phosphotransferase by using phylogenetic comparative analysis of the genome of the oxytetracycline-producing strain Streptomyces rimosus ATCC 10970. (bioinfor.com)
Kinetic2
  • Our kinetic analysis of the phosphotransferase reaction is consistent with a sequential mechanism of substrate addition and product release. (rpi.edu)
  • Here are the kinetic parameters of the streptomycin phosphotransferase APH(3″)-Id: Km 80.4 μM, Vmax 6.45 μmol/min/mg and kcat 1.73 s−1. (bioinfor.com)
Transfers2
  • Specifically, GlcNAc-1-phosphotransferase transfers a molecule called GlcNac-1-phosphate to a newly produced hydrolase. (medlineplus.gov)
  • We have demonstrated previously that the formation of the polymer is catalyzed by a phosphotransferase which transfers N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to the 4-hydroxyl of the N-acetylglucosamine on the nonreducing end of the growing chain. (rpi.edu)
Activity1
  • These mutations result in reduced the activity of GlcNAc-1-phosphotransferase, which disrupts tagging of hydrolases with M6P. (medlineplus.gov)
Mutations1
  • Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase", Nature Medicine , vol. 11, 2006, pp. 1109-1112. (uni-bielefeld.de)
System2
  • The Phosphoenolpyruvate Phosphotransferase System (PTS) is a primary mechanism by which many bacteria transport sugars and sense the carbon state of the cell. (umd.edu)
  • phosphoenolpyruvate-dependent sugar phosphotransferase system [Interproscan]. (ntu.edu.sg)
Crystal structure1
  • Crystal structure of AphA class B acid phosphatase/phosphotransferase complexed with adenosine. (expasy.org)
Kinase2
  • Urkinase: structure of acetate kinase, a member of the ASKHA superfamily of phosphotransferases. (expasy.org)
  • Creatine Kinase (CK) also known as creatine phosphokinase (CPK) and ATP: creatine N-phosphotransferase is a common cellular enzyme (EC 2.7.3.2). (abcam.com)
Bacterial phosphotransferase system3
  • The bacterial phosphotransferase system (PTS) couples phosphoryl transfer, via a series of bimolecular protein-protein interactions, to sugar transport across the membrane. (nih.gov)
  • The bacterial phosphotransferase system (PTS)2 couples phorylated complex is the same as that in the unphosphoryla- sequential phosphoryl transfer via a series of biomolecular pro- ted complex. (nih.gov)
  • 2] "Sugar transport by the bacterial phosphotransferase system. (tcdb.org)
Neomycin2
  • A chimeric gene was constructed encoding the 36-amino acid transit peptide of a chlorophyll a b-binding protein (AB) and 17 amino acids of the mature protein, linked to the amino terminus of neomycin phosphotransferase II (NPT-II). (ttu.edu)
  • Results revealed that primers for neomycin phosphotransferase ( nptII ) and aminoglycoside 3″ adenyl-transferase ( aadA ) were amplified in the majority of the 36 DNA screened samples. (springeropen.com)
Phosphoenolpyruvate-dependent sugar phosphotransferase system1
  • The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. (uniprot.org)
Genes2
  • The recent identification of two genes, GNPTAB and GNPTG, encoding the three subunits of GlcNac-1-phosphotransferase leads to an improvement of both pre- and postnatal diagnosis of affected individuals, and permits the analysis of structural requirements for efficient formation of mannose 6-phosphate residues on lysosomal enzymes. (nih.gov)
  • PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved in sugar utilization. (nih.gov)
Paralogous Phosphotransferase Systems1
  • Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems. (nih.gov)
Proteins2
  • Rifampin phosphotransferases (RPH) belong to a recently identified antibiotic-resistance proteins family members that inactivates rifampin the first-line medication against tuberculosis by phosphorylation. (biomarketx.net)
  • Proteins of the GHP family are generally about 500 amino acids in length, although the Gram-positive bacterial lactose permeases are larger, due to a C-terminal hydrophilic domain that is involved in regulation by the phosphotransferase system (TC #4.A.1). (tcdb.org)
Transport to lysosomes1
  • GlcNAc-1-phosphotransferase helps prepare certain newly made enzymes for transport to lysosomes. (medlineplus.gov)
Mucolipidosis type1
  • Defects in the GlcNac-1-phosphotransferase complex cause two diseases, mucolipidosis type II and III, which are characterized by missorting and cellular loss of lysosomal enzymes, and lysosomal accumulation of storage material. (nih.gov)
Resistance2
  • Recently an antibiotic-resistance protein family RIF phosphotransferase (RPH) was found to inactivate RIF by phosphorylating it at the hydroxyl Ivacaftor attached to the C21 of its ansa chain. (biomarketx.net)
  • A bifunctional aminoglycoside acetyltransferase/phosphotransferase conferring tobramycin resistance provides an efficient selectable marker for plastid transformation. (mpg.de)
GNPTAB1
  • Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition. (nih.gov)
Molecule2
  • GlcNAc-1-phosphotransferase is involved in the first step of making a molecule called mannose-6-phosphate (M6P). (medlineplus.gov)
  • Specifically, GlcNAc-1-phosphotransferase transfers a molecule called GlcNac-1-phosphate to a newly produced hydrolase. (medlineplus.gov)
Descriptor1
  • Phosphotransferases (Paired Acceptors)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
GNPTG gene: MedlinePlus Genetics
GNPTG gene: MedlinePlus Genetics (medlineplus.gov)
Macrolide-Resistant Shigella sonnei - Volume 14, Number 8-August 2008 - Emerging Infectious Diseases journal - CDC
Macrolide-Resistant Shigella sonnei - Volume 14, Number 8-August 2008 - Emerging Infectious Diseases journal - CDC (wwwnc.cdc.gov)
Mucolipidosis III alpha/beta: MedlinePlus Genetics
Mucolipidosis III alpha/beta: MedlinePlus Genetics (medlineplus.gov)
Antimicrobial Resistance Gene Delivery in Animal Feeds - Volume 10, Number 4-April 2004 - Emerging Infectious Diseases journal ...
Antimicrobial Resistance Gene Delivery in Animal Feeds - Volume 10, Number 4-April 2004 - Emerging Infectious Diseases journal ... (wwwnc.cdc.gov)
Homoserine kinase - Wikipedia
Homoserine kinase - Wikipedia (en.wikipedia.org)
Issue: Molecular Cell
Issue: Molecular Cell (cell.com)
Consensus pan-genome assembly of the specialised wine bacterium Oenococcus oeni | BMC Genomics | Full Text
Consensus pan-genome assembly of the specialised wine bacterium Oenococcus oeni | BMC Genomics | Full Text (bmcgenomics.biomedcentral.com)
Metabolites | Free Full-Text | Modelling hCDKL5 Heterologous Expression in Bacteria
Metabolites | Free Full-Text | Modelling hCDKL5 Heterologous Expression in Bacteria (mdpi.com)
Find Research outputs - Heriot-Watt Research Portal
Find Research outputs - Heriot-Watt Research Portal (researchportal.hw.ac.uk)
KEGG REACTION: R00200
KEGG REACTION: R00200 (genome.jp)
Phosphatidylinositol-4-Phosphate 3-Kinase | Harvard Catalyst Profiles | Harvard Catalyst
Phosphatidylinositol-4-Phosphate 3-Kinase | Harvard Catalyst Profiles | Harvard Catalyst (connects.catalyst.harvard.edu)
SMART: STYKc domain annotation
SMART: STYKc domain annotation (smart.embl-heidelberg.de)
KEGG REACTION: R05647
KEGG REACTION: R05647 (genome.jp)
Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings | Nature Genetics
Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings | Nature Genetics (nature.com)
KEGG REACTION: R02439
KEGG REACTION: R02439 (genome.jp)
MeSH Browser
MeSH Browser (meshb.nlm.nih.gov)
Escherichia coli as Reservoir for Macrolide Resistance Genes - Volume 15, Number 10-October 2009 - Emerging Infectious Diseases...
Escherichia coli as Reservoir for Macrolide Resistance Genes - Volume 15, Number 10-October 2009 - Emerging Infectious Diseases... (wwwnc.cdc.gov)
Structural relationship between the genes encoding 3'-aminoglycoside phosphotransferases in Campylobacter and in gram-positive...
Structural relationship between the genes encoding 3'-aminoglycoside phosphotransferases in Campylobacter and in gram-positive... (research.pasteur.fr)
SMART: S_TKc domain annotation
SMART: S_TKc domain annotation (smart.embl.de)
SMART: TyrKc domain annotation
SMART: TyrKc domain annotation (smart.embl.de)
Recombinant Anti-Creatine Kinase MM antibody [EPR25358-10] (ab283683) | Abcam
Recombinant Anti-Creatine Kinase MM antibody [EPR25358-10] (ab283683) | Abcam (abcam.com)
Figure 2 - Antimicrobial Drug Resistance: Prediction Is Very Difficult, Especially about the Future - Volume 11, Number 10...
Figure 2 - Antimicrobial Drug Resistance: "Prediction Is Very Difficult, Especially about the Future" - Volume 11, Number 10... (wwwnc.cdc.gov)
Figure 1 - Antimicrobial Drug Resistance: Prediction Is Very Difficult, Especially about the Future - Volume 11, Number 10...
Figure 1 - Antimicrobial Drug Resistance: "Prediction Is Very Difficult, Especially about the Future" - Volume 11, Number 10... (wwwnc.cdc.gov)
Genetics of Antimicrobial Resistance in Staphylococcus Aureus
Genetics of Antimicrobial Resistance in Staphylococcus Aureus (medscape.com)
Real-time PCR as a Diagnostic Tool for Bacterial Diseases
Real-time PCR as a Diagnostic Tool for Bacterial Diseases (medscape.com)