A genus of the family BUNYAVIRIDAE comprising many viruses, most of which are transmitted by Phlebotomus flies and cause PHLEBOTOMUS FEVER. The type species is RIFT VALLEY FEVER VIRUS.
Virus diseases caused by the BUNYAVIRIDAE.
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.
A species in the genus PHLEBOVIRUS causing PHLEBOTOMUS FEVER, an influenza-like illness. Related serotypes include Toscana virus and Tehran virus.
Influenza-like febrile viral disease caused by several members of the BUNYAVIRIDAE family and transmitted mostly by the bloodsucking sandfly Phlebotomus papatasii.
A family of viruses, mainly arboviruses, consisting of a single strand of RNA. Virions are enveloped particles 90-120 nm diameter. The complete family contains over 300 members arranged in five genera: ORTHOBUNYAVIRUS; HANTAVIRUS; NAIROVIRUS; PHLEBOVIRUS; and TOSPOVIRUS.
An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
A species in the genus PHLEBOVIRUS of the family BUNYAVIRIDAE, infecting vertebrates and vectored by ticks. It has not been associated with human disease though antibodies have been isolated from human sera.
A genus of the family BUNYAVIRIDAE named after NAIROBI SHEEP DISEASE, an acute, hemorrhagic, tick-borne, gastroenteritis affecting sheep and goats. The type species is Dugbe virus. Some viruses in this genus are capable of causing severe and fatal disease in humans.
A genus of the family BUNYAVIRIDAE containing over 150 viruses, most of which are transmitted by mosquitoes or flies. They are arranged in groups defined by serological criteria, each now named for the original reference species (previously called serogroups). Many species have multiple serotypes or strains.
Small, hairy, moth-like flies which are of considerable public health importance as vectors of certain pathogenic organisms. Important disease-related genera are PHLEBOTOMUS, Lutzomyia, and Sergentomyia.
Viruses containing two or more pieces of nucleic acid (segmented genome) from different parents. Such viruses are produced in cells coinfected with different strains of a given virus.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
Ribonucleic acid that makes up the genetic material of viruses.
A genus of the family Muridae having three species. The present domesticated strains were developed from individuals brought from Syria. They are widely used in biomedical research.
The relationships of groups of organisms as reflected by their genetic makeup.
The general name for NORTH AMERICA; CENTRAL AMERICA; and SOUTH AMERICA unspecified or combined.
Semidomesticated variety of European polecat much used for hunting RODENTS and/or RABBITS and as a laboratory animal. It is in the subfamily Mustelinae, family MUSTELIDAE.
A subnormal level of BLOOD PLATELETS.
An abnormal elevation of body temperature, usually as a result of a pathologic process.
A species in the genus Bornavirus, family BORNAVIRIDAE, causing a rare and usually fatal encephalitic disease in horses and other domestic animals and possibly deer. Its name derives from the city in Saxony where the condition was first described in 1894, but the disease occurs in Europe, N. Africa, and the Near East.
An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.
A family in the order MONONEGAVIRALES comprising one genus Bornavirus. This family has a unique form of mRNA processing: replication and transcription takes place in the nucleus.
An order of flightless birds comprising the ostriches, which naturally inhabit open, low rainfall areas of Africa.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
International collective of humanitarian organizations led by volunteers and guided by its Congressional Charter and the Fundamental Principles of the International Red Cross Movement, to provide relief to victims of disaster and help people prevent, prepare for, and respond to emergencies.
The systematic arrangement of entities in any field into categories classes based on common characteristics such as properties, morphology, subject matter, etc.
One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.

Detection of Toscana virus-specific immunoglobulins G and M by an enzyme-linked immunosorbent assay based on recombinant viral nucleoprotein. (1/89)

An enzyme-linked immunosorbent assay (ELISA) based on the recombinant Toscana virus nucleoprotein (rN) has been developed. Its sensitivity and specificity for the detection of virus-specific immunoglobulins G and M in human sera were similar to those of the ELISA that is based on an antigen extracted from infected mouse brain and that is routinely used for serodiagnosis.  (+info)

Seroprevalence of West Nile, Rift Valley, and sandfly arboviruses in Hashimiah, Jordan. (2/89)

We conducted a serosurvey among patients of a health center in Hashimiah, a Jordanian town of 30,000 inhabitants located near a wastewater treatment plant and its effluent channel. Serum samples from 261 patients >/=5 years of age were assessed for immunoglobulin G (IgG) and IgM antibodies against West Nile, sandfly Sicilian, sandfly Naples, and Rift Valley viruses; the seroprevalence of IgG antibodies was 8%, 47%, 30%, and 0%, respectively. Female participants were more likely to have been infected than male. Persons living within 2 km of the treatment plant were more likely to have been infected with West Nile (p=0.016) and sandfly Sicilian (p=0.010) viruses. Raising domestic animals within the house was a risk factor for sandfly Sicilian (p=0.003) but not for sandfly Naples virus (p=0.148). All serum samples were negative for IgM antibodies against the tested viruses. Our study is the first documentation of West Nile and sandfly viruses in Jordan and calls attention to the possible health hazards of living close to wastewater treatment plants and their effluent channels.  (+info)

Poised for contagion: evolutionary origins of the infectious abilities of invertebrate retroviruses. (3/89)

Phylogenetic analyses suggest that long-terminal repeat (LTR) bearing retrotransposable elements can acquire additional open-reading frames that can enable them to mediate infection. Whereas this process is best documented in the origin of the vertebrate retroviruses and their acquisition of an envelope (env) gene, similar independent events may have occurred in insects, nematodes, and plants. The origins of env-like genes are unclear, and are often masked by the antiquity of the original acquisitions and by their rapid rate of evolution. In this report, we present evidence that in three other possible transitions of LTR retrotransposons to retroviruses, an envelope-like gene was acquired from a viral source. First, the gypsy and related LTR retrotransposable elements (the insect errantiviruses) have acquired their envelope-like gene from a class of insect baculoviruses (double-stranded DNA viruses with no RNA stage). Second, the Cer retroviruses in the Caenorhabditis elegans genome acquired their envelope gene from a Phleboviral (single ambisense-stranded RNA viruses) source. Third, the Tas retroviral envelope (Ascaris lumricoides) may have been obtained from Herpesviridae (double-stranded DNA viruses, no RNA stage). These represent the only cases in which the env gene of a retrovirus has been traced back to its original source. This has implications for the evolutionary history of retroviruses as well as for the potential ability of all LTR-retrotransposable elements to become infectious agents.  (+info)

Encephalitis without meningitis due to sandfly fever virus serotype toscana. (4/89)

The role of Toscana (TOS) virus in producing encephalitis without meningitis is uncertain. We studied 2 cases of TOS virus encephalitis without meningitis by means of nested polymerase chain reaction assay and DNA sequencing. Findings confirm that TOS virus may directly cause encephalitis and suggest the usefulness of DNA sequencing in investigating relationships between TOS virus molecular patterns and the spectrum of neurological involvement.  (+info)

Characterization of the Golgi retention motif of Rift Valley fever virus G(N) glycoprotein. (5/89)

As Rift Valley fever (RVF) virus, and probably all members of the family Bunyaviridae, matures in the Golgi apparatus, the targeting of the virus glycoproteins to the Golgi apparatus plays a pivotal role in the virus replication cycle. No consensus Golgi localization motif appears to be shared among the glycoproteins of these viruses. The viruses of the family Bunyaviridae synthesize their glycoproteins, G(N) and G(C), as a polyprotein. The Golgi localization signal of RVF virus has been shown to reside within the G(N) protein by use of a plasmid-based transient expression system to synthesize individual G(N) and G(C) proteins. While the distribution of individually expressed G(N) significantly overlaps with cellular Golgi proteins such as beta-COP and GS-28, G(C) expressed in the absence of G(N) localizes to the endoplasmic reticulum. Further analysis of expressed G(N) truncated proteins and green fluorescent protein/G(N) chimeric proteins demonstrated that the RVF virus Golgi localization signal mapped to a 48-amino-acid region of G(N) encompassing the 20-amino-acid transmembrane domain and the adjacent 28 amino acids of the cytosolic tail.  (+info)

Phylogenetic relationships among members of the genus Phlebovirus (Bunyaviridae) based on partial M segment sequence analyses. (6/89)

Viruses in the Phlebovirus genus of the family Bunyaviridae cause clinical syndromes ranging from a short, self-limiting febrile illness to fatal haemorrhagic fever. The genus currently consists of 68 antigenically distinct virus serotypes, most of which have not been genetically characterized. RT-PCR with four 'cocktail' primers was performed to amplify a region of the M segment of the genome of 24 phleboviruses included in the sandfly fever Naples, sandfly fever Sicilian and Punta Toro serocomplexes. Partial M segment sequences were successfully obtained and phylogenetic analysis was performed. The three resultant genotypic lineages were consistent with serological data. The sequence divergences were 27.6 % (nucleotide) and 25.7 % (amino acid) within the Sicilian serocomplex, 33.7 % (nucleotide) and 34.4 % (amino acid) within the Naples serocomplex and 35.6 % (nucleotide) and 37.5 % (amino acid) within the Punta Toro serocomplex. Overall, the diversities among viruses of Sicilian, Naples and Punta Toro serocomplexes were 48.2 % and 57.6 % at the nucleotide and amino acid levels, respectively. This high genetic divergence may explain the difficulties in designing a consensus primer pair for the amplification of all the phleboviruses using RT-PCR. It also suggests that infection with one genotype may not completely immunize against infection with all other genotypes in a given serocomplex. These findings have implications for potential vaccine development and may help explain clinical reports of multiple episodes of sandfly fever in the same individual.  (+info)

Induction of severe disease in hamsters by two sandfly fever group viruses, Punta toro and Gabek Forest (Phlebovirus, Bunyaviridae), similar to that caused by Rift Valley fever virus. (7/89)

Adult golden hamsters inoculated subcutaneously with either of two sandfly fever group viruses, Punta Toro and Gabek Forest (Phlebovirus, Bunyaviridae), developed a fulminating fatal illness characterized by hepatic and splenic necrosis and interstitial pneumonitis. Most animals died within three days after infection; this was accompanied by high levels of viremia. Necropsy and histopathologic examination of the infected animals revealed pathologic changes involving multiple organs that resembled those described in Rift Valley fever. These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in studying the pathogenesis of severe phlebovirus infection and for testing potential therapeutic agents.  (+info)

Association of the nonstructural protein NSs of Uukuniemi virus with the 40S ribosomal subunit. (8/89)

The small RNA segment (S segment) of Uukuniemi (UUK) virus encodes two proteins, the nucleocapsid protein (N) and a nonstructural protein (NSs), by an ambisense strategy. The function of NSs has not been elucidated for any of the bunyaviruses expressing this protein. We have now expressed the N and NSs proteins in Sf9 insect cells by using the baculovirus expression system. High yields of both proteins were obtained. A monospecific antibody was raised against gel-purified NSs and used to study the synthesis and localization of the protein in UUK virus-infected BHK21 cells. While the N protein was detected as early as 4 h postinfection (p.i.), NSs was identified only after 8 h p.i. Both proteins were still synthesized at high levels at 24 h p.i. The half-life of NSs was about 1.5 h, while that of the N protein was several hours. Sucrose gradient fractionation of [35S]methionine-labeled detergent-solubilized extracts of infected BHK21 cells indicated that NSs was firmly associated with the 40S ribosomal subunit. This association took place shortly after translation and was partially resistant to 1 M NaCl. NSs expressed by using the T7 vaccinia virus expression system, as well as in vitro-translated NSs, was also associated with the 40S subunit. In contrast, in vitro-translated N protein was found on top of the gradient. Immunolocalization of NSs, in UUK virus-infected cells, by using an affinity-purified antibody showed a granular cytoplasmic staining. A very similar pattern was seen for cells expressing NSs from a cDNA copy by using a vaccinia virus expression system. No staining was observed in the nuclei in either case. Furthermore, NSs was found neither in virions nor in nucleocapsids isolated from infected cells. In vivo labeling with 32Pi indicated that NSs is not phosphorylated. The possible function of NSs is discussed in light of these results.  (+info)

TY - JOUR. T1 - Haemaphysalis longicornis ticks as reservoir and vector of severe fever with thrombocytopenia syndrome virus in China. AU - Luo, Li Mei. AU - Zhao, Li. AU - Wen, Hong Ling. AU - Zhang, Zhen Tang. AU - Liu, Jian Wei. AU - Fang, Li Zhu. AU - Xue, Zai Feng. AU - Ma, Dong Qiang. AU - Zhang, Xiao Shuang. AU - Ding, Shu Jun. AU - Lei, Xiao Ying. AU - Yu, Xue Jie. PY - 2015/9/1. Y1 - 2015/9/1. N2 - Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in East Asia caused by SFTS virus (SFTSV), a newly discovered phlebovirus. The Haemaphysalis longicornis tick has been suspected to be the vector of SFTSV. To determine whether SFTSV can be transmitted among ticks, from ticks to animals, and from animals to ticks, we conducted transmission studies between developmental stages of H. longicornis ticks and between ticks and mice. Using reverse transcription PCR, we also analyzed the prevalence of SFTSV infection among H. longicornis ticks collected from ...
Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the most dangerous pathogens by the World Health Organization, has 12-30% fatality rates with a characteristic thrombocytopenia syndrome. With a majority of clinically diagnosed SFTSV patients older than ~50 years of age, age is a critical risk factor for SFTSV morbidity and mortality. Here, we report an age-dependent ferret model of SFTSV infection and pathogenesis that fully recapitulates the clinical manifestations of human infections. Whereas young adult ferrets (≤2 years of age) did not show any clinical symptoms and mortality, SFTSV-infected aged ferrets (≥4 years of age) demonstrated severe thrombocytopenia, reduced white blood cell counts and high fever with 93% mortality rate. Moreover, a significantly higher viral load was observed in aged ferrets. Transcriptome analysis of SFTSV-infected young ferrets revealed strong interferon-mediated anti-viral signalling, whereas inflammatory immune responses were markedly
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease. Haemophysalis longicornis ticks have been considered the vector of severe fever with thrombocytopenia syndrome virus (SFTSV). However, clear data on the transmission of SFTS from ticks to humans are limited. We report an 84-year-old woman who presented with fever and altered mentality, which was confirmed as SFTS with encephalopathy by reverse-transcription polymerase chain reaction in blood and cerebrospinal fluid. The SFTSV was also identified in the tick that bit her, H. longicornis. Phylogenetic analyses indicated that the SFTSV from the patient and the tick was identical. The patient gradually recovered with treatments of corticosteroids and immunoglobulin. These findings provide further evidence of SFTS viral transmission from H. longicornis to human.
Adult golden hamsters inoculated subcutaneously with either of two sandfly fever group viruses, Punta Toro and Gabek Forest (Phlebovirus, Bunyaviridae), developed a fulminating fatal illness characterized by hepatic and splenic necrosis and interstitial pneumonitis. Most animals died within three days after infection; this was accompanied by high levels of viremia. Necropsy and histopathologic examination of the infected animals revealed pathologic changes involving multiple organs that resembled those described in Rift Valley fever. These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in studying the pathogenesis of severe phlebovirus infection and for testing potential therapeutic agents.
Abstract. Severe fever with thrombocytopenia syndrome (SFTS), which is caused by a novel bunyavirus, is an emerging infectious disease in China. In 2011, this new virus was designated as severe fever with thrombocytopenia syndrome virus (SFTSV). The aim of the present study was to determine the seroprevalence and risk factors of SFTSV infection. The investigation was conducted among the general population in Jiangsu Province, China in 2011. A total of 2,510 serum samples were collected. Testing by enzyme-linked immunosorbent assay was conducted to determine the seroprevalence of SFTSV infection. Result showed that the overall seroprevalence of SFTSV infection was 0.44% (11 of 2,510) in seven counties in Jiangsu Province. Multiple variable logistic regression analysis showed that raising goats, farming, and grazing were risk factors for SFTSV infection. Raising goats, farming, and grazing might be important risk factors for virus exposure, and appropriate health education could be useful in preventing
Severe fever with thrombocytopenia syndrome (SFTS) was an emerging hemorrhagic fever that was caused by a tick-borne bunyavirus, SFTSV. Although SFTSV nonstructural protein can inhibit type I interferon (IFN-I) production Ex Vivo and IFN-I played key role in resistance SFTSV infection in animal model, the role of IFN-I in patients is not investigated. We have assayed the concentration of IFN-α, a subtype of IFN-I as well as other cytokines in the sera of SFTS patients and the healthy population with CBA (Cytometric bead array) assay. The results showed that IFN-α, tumor necrosis factor (TNF-α), granulocyte colony-stimulating factor (G-CSF), interferon-γ (IFN-γ), macrophage inflammatory protein (MIP-1α), interleukin-6 (IL-6), IL-10, interferon-inducible protein (IP-10), monocyte chemoattractant protein (MCP-1) were significantly higher in SFTS patients than in healthy persons (p | 0.05); the concentrations of IFN-α, IFN-γ, G-CSF, MIP-1α, IL-6, and IP-10 were significant higher in severe SFTS
Background: Severe fever with thrombocytopenia syndrome (SFTS) is a newly emerging infectious disease caused by a novel phlebovirus SFTS virus (SFTSV). The major clinical signs and symptoms are fever, nausea, anorexia, thrombocytopenia, leukopenia, lymphadenopathy and hemorrhagic tendency. SFTS was first reported in China, followed by South Korea and Japan. In South Korea, the first patient was reported in 2012 and 35 persons were diagnosed with SFTS in 2013. We conducted a sero-surveillance study of SFTSV of healthy people on Mui Island.. Methods: Mui Island, located in Incheon, western South Korea (126.3876-126.4472E, 37.3648-37.4128N), has an area of 10.27 km2 and a population of 835 registered persons. The majority of residents are engaged in both agriculture and coastal fishery. Blood samples were collected during November 2014 from 203 healthy volunteers (female 127, male 76, 30 to 97 years old, median 67). The IgG and IgM antibody against SFTSV was detected using indirect ...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease recently discovered in northeast and central China. SFTS cause high fatality rate of 12% and as high as 30% in some areas. The major clinical symptoms of SFTS are fever, vomiting, diarrhea, multiple organ failure, thrombocytopenia (low platelet count), leucopenia (low white blood cell count), and elevated liver enzyme level.SFTS occurs in rural areas from March to November, and a majority of cases are from April to July. In 2009 Xue-jie Yu and colleagues isolated the SFTS virus (SFTSV) from SFTS patients blood. SFTSV is a Phlebovirus in the family of Bunyaviridae. The life cycle of the SFTSV most likely involves arthropod vectors and animal hosts. Humans are accidental hosts and play no role in the life cycle of the SFTSV. SFTSV has been detected from Haemaphysalis longicornis ticks. The transmission routine of SFTSV is unknown, but person-to-person transmission either plays no role or at least is not an ...
PubMedID: 26322483 | Apodemus agrarius is a potential natural host of severe fever with thrombocytopenia syndrome (SFTS)-causing novel bunyavirus. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | 10/1/2015
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever caused by a tick-borne banyangvirus and is associated with high fatality. Despite increasing incidence of SFTS and serious public health concerns in East Asia, the pathogenesis of lethal SFTS virus (SFTSV) infection in humans is not fully understood. Numbers of postmortem examinations to determine target cells of the viral infection have so far been limited. Here we showed that B cells differentiating into plasmablasts and macrophages in secondary lymphoid organs were targets for SFTSV at the end stage of lethal infection, and the majority of SFTSV-infected cells were B cell-lineage lymphocytes. In affected individuals, B cell-lineage lymphocytes with SFTSV infection were widely distributed in both lymphoid and nonlymphoid organs, and infiltration of these cells into the capillaries of the organs could be observed occasionally. Moreover, a human plasmablastic lymphoma cell line, PBL-1, was susceptible to SFTSV ...
The Centers for Disease Control and Prevention (CDC) in collaboration with health officials in Missouri and Tennessee have identified six new cases of people sick with Heartland virus: five in Missouri and one in Tennessee. The new cases, discovered in 2012 and 2013, are in addition to two discovered in 2009 and are described today in CDCs Morbidity and Mortality Weekly Report.. Heartland virus was first reported in two northwestern Missouri farmers who were hospitalized in 2009 with what was thought to be ehrlichiosis, a tick-borne disease. However, the patients failed to improve with treatment and testing failed to confirm ehlrlichiosis. Working with state and local partners, CDC eventually identified the cause of the mens illness: a previously unknown virus in the phlebovirus family now dubbed Heartland virus.. Ongoing investigations have yielded six more cases of Heartland virus disease, bringing to eight the total number of known cases. All of the case-patients were white men over the age ...
T-705 inhibited SFTSV replication in vitro and showed therapeutic efficacy in vivo. T-705 has been shown to possess favorable antiviral activities against various RNA viruses and has a therapeutic effect on these viral infections in animal models (16, 31). T-705 was identified as a potential drug for the treatment of influenza virus infection. Regarding the mechanism of action of T-705, it has been reported that T-705 is converted to its phosphoribosylated metabolites (T-705RMP and T-705RTP) by host cellular kinases and that T-705RTP inhibits the activity of the RNA-dependent RNA polymerase of a number of viruses (33). Recently, T-705 has been licensed for use by the Ministry of Health, Labour and Welfare of Japan. However, its use has been limited to the events of the outbreak due to novel or reemerging influenza viral infections. T-705 was also considered as a potential therapeutic agent against Ebola virus disease (EVD) during the 2014-2015 EVD outbreak throughout West Africa ...
PubMedID: 26564632 | [Epidemiological analysis on severe fever with thrombocytopenia syndrome under the national surveillance data from 2011 to 2014, China]. | Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi | 6/1/2015
A Case of Severe Fever With Thrombocytopenia Syndrome Accompanied by Self-Limiting Severe Proteinuria That Inversely Correlated With the Platelet Count
BioMed Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies covering a wide range of subjects in life sciences and medicine. The journal is divided into 55 subject-specific sections.
If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible ...
We analyzed the whole-genome sequence of African swine fever virus Belgium 2018/1. The strain fits into the European genotype II (>99.98% identity). The high-coverage sequence revealed 15 differences compared with an improved African swine fever viru ...
TY - JOUR. T1 - 18F-FDG PET imaging for identifying the dynamics of intestinal disease caused by SFTSV infection in a mouse model. AU - Hayasaka, Daisuke. AU - Nishi, Kodai. AU - Fuchigami, Takeshi. AU - Shiogama, Kazuya. AU - Onouchi, Takanori. AU - Shimada, Satoshi. AU - Tsutsumi, Yutaka. AU - Morita, Kouichi. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Severe fever with thrombocytopenia syndrome (SFTS) is an emerging disease that causes fever, enteritis, thrombocytopenia, and leucopenia and can be fatal in up to 30% of cases. However, the mechanism of severe disease is not fully understood. Molecular imaging approaches, such as positron-emission tomography (PET), are functional in vivo imaging techniques that provide real-time dynamics of disease progression, assessments of pharmacokinetics, and diagnoses for disease progression. Molecular imaging also potentially provides useful approaches to explore the pathogenesis of viral infections. Thus, the purpose of this study was to image the pathological ...
Toscana and sandfly fever Sicilian viruses (TOSV and SFSV, respectively), both transmitted by sand flies, are prominent human pathogens in the Old World. Of 1,086 serum samples collected from cattle and sheep during 2013 in various regions of Kosovo ...
The location was named Punta Rasca (Spanish for smooth or flat point and later corrupted to Punta Rassa) by the Spanish Conquistadors in the mid-16th century, who unloaded cattle in the area. Punta Rassa was a thriving cattle shipping town in the 1800s. Florida cattle would be loaded at the port onto ships destined for Cuba. It was one of the home bases for the King of the Cracker Cowboys Jake Summerlin, who by the time he was 40 was one of the wealthiest of the Florida cattle barons. The town of Punta Rassa was lined with wooden buildings, including a hotel and several bars, which were frequented by the many merchants and cattle sellers. Between 1835 and 1865, Punta Rassa was a site of many Indian skirmishes during the Seminole Indian Wars. As a result, Fort Dulany was built there in 1838, as an army supply depot. A hurricane destroyed Fort Dulany in October 1841, and the military was forced to look for a site less exposed to storms from the Gulf of Mexico. As a result of the search, ...
We have reported the case of a severely ill patient with SFTSV-associated encephalitis/encephalopathy in whom an SCC lesion was detected, but showed spontaneous resolution. The presence of a reversible SCC lesion has been reported in patients with a broad spectrum of diseases and conditions, and is referred to as RESLES [3]. Infection is the most common cause of this abnormality. To the best of our knowledge, this is the first reported case of RESLES in a patient with SFTSV infection.. The common neurological symptoms of RESLES associated with encephalitis/encephalopathy may include delirium, short-term disturbance of consciousness, and seizures, but usually patients show complete recovery without neurological sequelae after a short disease course [13, 14]. Although CNS manifestations are common in patients with SFTS, signs of severe CNS disturbance, such as coma and convulsion, are thought to be major clinical indicators of poor prognosis [2]. An epidemiologic study of 538 patients with SFTS ...
For sale: Houses at Punta del Este, Properties, apartments and houses for rent and sale at Punta del Este La Barra José Ignacio Punta Ballena. Countrysides, investments, real state.
The pyrimidine nucleoside analog FIAC and its primary deaminated uracil metabolite FIAU are highly and specifically active compounds in vitro against several herpes group viruses, particularly herpes simplex virus (HSV) types 1 and 2, varicella zoster (VZV), and cytomegalovirus (CMV), as well as hepatitis B virus (HBV). Since FIAU is the primary metabolite of FIAC and the administration of FIAU simplifies the metabolism of FIAC, it is anticipated from clinical studies of FIAC that FIAU will be tolerated at least as well as FIAC. A single-dose, pharmacokinetic (blood level) study showed that FIAC, when taken orally, is readily absorbed into the bloodstream, and most of it is converted to FIAU. Daily oral doses are expected to provide concentrations of FIAU exceeding the in vitro minimum inhibitory concentration for nearly all the herpes group viruses.. HIV-infected patients with Karnofsky scores at least 80 (with or without documented recurrent herpes group infections) are successively entered ...
The pyrimidine nucleoside analog FIAC and its primary deaminated uracil metabolite FIAU are highly and specifically active compounds in vitro against several herpes group viruses, particularly herpes simplex virus (HSV) types 1 and 2, varicella zoster (VZV), and cytomegalovirus (CMV), as well as hepatitis B virus (HBV). Since FIAU is the primary metabolite of FIAC and the administration of FIAU simplifies the metabolism of FIAC, it is anticipated from clinical studies of FIAC that FIAU will be tolerated at least as well as FIAC. A single-dose, pharmacokinetic (blood level) study showed that FIAC, when taken orally, is readily absorbed into the bloodstream, and most of it is converted to FIAU. Daily oral doses are expected to provide concentrations of FIAU exceeding the in vitro minimum inhibitory concentration for nearly all the herpes group viruses.. HIV-infected patients with Karnofsky scores at least 80 (with or without documented recurrent herpes group infections) are successively entered ...
Looking for Phleboviruses? Find out information about Phleboviruses. An acute viral infection, transmitted by the fly Phlebotomus papatosii and characterized by fever, pains in the head and eyes, inflammation of the... Explanation of Phleboviruses
The first phlebovirus found to cause illness in humans in the Western Hemisphere was discovered due to two severely sick farmers, U.S. researchers say.
One year ago today Peter Gleick posed as a Heartland insider to expose the evil nature of this institution. For the back story see: Heartland Institute: Hey Kids, Have a Smoke and Denial where I showed how Heartland was trying to undermine the science education being provided to our K-12 school children. Unfortunately, much of the news was focused on what Dr. Gleick did wrong and not what Heartland was doing wrong. As I wrote in Do Not Take Your Eyes Off Lex Luthor (Heartland Institute), Peter Gleick is a great man who made a mistake. The focus should NOT have been on him but on Heartland. It is easy to point the finger at Superman when he makes a mistake than it is to Lex Luthor who is expected to be the bad guy. ...
Punta Gorda FL - Learn how to lose weight fast! The best products and recommendations in Punta Gorda Florida for the fastest weight loss possible.
PUNTA DEL CERRO Postal Codes - Find the list of all zip codes or postal codes belongs to PUNTA DEL CERRO area of LA RIOJA, Argentina.
Sandals è comunemente visto nelle giornate estive.Per quelle donne che cercano per la bellezza e la moda, sandali stiletto è la scelta popolare.Noi abbiamo la nostra squisita Rivetti incorporato Scarpe a punta tacco nudo delle donne a spillo sandali offerti qui.La prima vista si vede, si sarà stupito i rivetti completamente decorate, giusto?Essa porta stile punk al senso generale.Ladozione di materiali di qualità superiore e di lavoro con meticolosa maestria, lo stiletto garantisce una buona resistenza allusura ed un eccellente comfort.punta a punta e il design del tallone nudo porta estetica e traspirabilità.Come si può perdere fuori ...
View deals for Four Seasons Resort Punta Mita, including fully refundable rates with free cancellation. Guests praise the helpful staff. Punta De Mita Beach is minutes away. WiFi and parking are free, and this hotel also features 3 outdoor pools.
Gokuden Mutsuyo , Nishi Nobuyuki , Ootsubo Mitsuhiro , Fukushi Shuetsu , Saijo Masayuki , Nakadouzono Fumiko , Iwamoto Yuka , Yamamoto Mami , Hozumi Nodoka , Nakayama Kouichiro , Ishitani Kanji ,p,Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infection with a high mortality rate. It is caused by the SFTS virus (SFTSV) and is endemic in some areas in western Japan, … Japanese Journal of Infectious Diseases 71(3), 225-228, 2018 J-STAGE Ichushi Web ...
Tim writes: in twiv 221 Dickson was in his full form funny and breathing loudly into mic. Not sure whether to find endearing or irritating. : ) Dave writes: Thank you again for the TWiV mention! The models do work well and I am now in the process of assessing the success. Have a great week! Dave PS Lawrence University is in Appleton Wisconsin just south of Green Bay (home of the packers) Richard writes: Hi Vince and co-presenters, Enjoyed your last TWIV about newly emerging bunyaviruses. A couple of comments. Firstly, SFTSV (that really is a dreadful name, it goes against the tradition of naming bunyaviruses after their place of isolation, and severe fever and thrombocytopenia are hardly specific to this virus, think about all the arenaviruses causing haemorrhagic fever). I dont know whether this was picked up previously on TWIV but there was a report in NEJM about another phlebovirus, called Heartland virus, that caused two independent human infections associated with tick bites in Missouri. McMullan
A lifeguard wearing a protective face mask takes the temperature of a woman at a newly reopened beach after months of closure due to an outbreak of the coronavirus disease (COVID-19), at Punta Hidalgo, in Punta Ala, Italy May 31, 2020. REUTERS/Jennifer Lorenzini. ...
Best South American Restaurants in Punta Cana, La Altagracia Province: Find TripAdvisor traveler reviews of Punta Cana South American restaurants and search by price, location, and more.
Book holiday rentals near Spiaggia di Punta Don Diego Loiri Porto San Paolo on Tripadvisor! View the Best 209 traveler reviews from properties near Spiaggia di Punta Don Diego in Loiri Porto San Paolo, Italy
Book holiday rentals near Peace River Wildlife Center Punta Gorda on Tripadvisor! View the Best 1,093 traveler reviews from properties near Peace River Wildlife Center in Punta Gorda, FL
Four Seasons Resort Punta Mita offers the ultimate resort wedding experience near Puerto Vallarta amid a variety of luxury venues, services and amenities.
Surf lodge Punta de Lobos, Pichilemu: 34 Hotel Reviews, 143 traveller photos, and great deals for Surf lodge Punta de Lobos, ranked #3 of 3 hotels in Pichilemu and rated 4 of 5 at TripAdvisor
Best Late Night Restaurants in Punta Gorda, Toledo District: Find TripAdvisor traveller reviews of the best Punta Gorda Late Night Restaurants and search by price, location, and more.
As to the thrombocytopenic category, there is physiological HIT-I and an immunological (bad) HIT-II. Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy (especially unfractionated heparin [UFH]), with a high risk of potentially catastrophic venous or arterial thrombosis (HITTS) and high mortality. Our group knows of a local death in 2004 that may have been due to HITTS. As with so many other situations in medical diagnosis, arriving at a correct diagnosis requires discerning clinical acumen (which, extremely importantly, serves to increase the prevelance of this disorder in a lab-test population). The HIT antibody disappears to non-detectibility in about 100 days; so, a pre-therapeutic screening testing is not logical.. Heparin fragments with molecular weights larger than 5,000 Kd...in highest concentration in unfractionated heparin (UFH) preparations...are needed to generate HIT IgG antibodies (theoretically, there may be rare IgA or IgM cases). Low molecular ...
Health,...EFFINGHAM Ill. April 23 /- Heartland Dental Care Inc. ... ...The six acquisitions include practices in Dickson Tenn. Lexington K... ...,Heartland,Dental,Care,,Inc.,Adds,Eight,Dental,Practices,In,First,Quarter,2009,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Theodore AL (PRWEB) January 23 2013 Taylor-Wharton Cryogenics LCC announced today its new Toro product line of artificial insemination (AI) products from its CryoScience business unit. This rugged unit built for durability provides longer hold times at cryogenic temperatures (-196°C) for cattle breeders who need to hold bovine sperm for an extended per,Taylor-Wharton,Announces,Release,of,New,Toro,Line,of,Animal,Artificial,Insemination,Products,biological,advanced biology technology,biology laboratory technology,biology device technology,latest biology technology
Toro 260-06-04 1 in. FPT Electric Valve Heavy duty. Hardworking. The Toro 250/260 and 254/264 Series globe-style valves are made to withstand all that a large residential or light commercial application can dish out. The durable and dependable, glass
Re Joint Use of El Toro Opposed by 59% in Poll, (Nov. 16):The poll sponsored by the coalition for a responsible airport solution regarding the joint civil/military use of El Toro Marine Corps Air
Location Maps of Concha y Toro Vine in Chile and its surroundings tourist attractions. Geographic satellite location of Concha y Toro Vine
Disease X represents the knowledge that a serious international epidemic could be caused by a pathogen currently unknown to cause human disease, and so the R&D Blueprint explicitly seeks to enable cross-cutting R&D preparedness that is also relevant for an unknown Disease X as far as possible.. A number of additional diseases were discussed and considered for inclusion in the priority list, including: Arenaviral hemorrhagic fevers other than Lassa Fever; Chikungunya; highly pathogenic coronaviral diseases other than MERS and SARS; emergent non-polio enteroviruses (including EV71, D68); and Severe Fever with Thrombocytopenia Syndrome (SFTS).. These diseases pose major public health risks and further research and development is needed, including surveillance and diagnostics. They should be watched carefully and considered again at the next annual review. Efforts in the interim to understand and mitigate them are encouraged.. Although not included on the list of diseases to be considered at the ...
Sidwell, R.W., J.H. Huffman, D.L. Barnard, D.F. Smee, R.P. Warren, M.A. Chirigos, M. Kende and J. Huggins. 1994. Antiviral and immunomodulating inhibitors of experimentallyinduced Punt Toro virus infections. Antiviral Res. 25:105-122. PMID: 7847873. ...
Test-drive the new 2018 Toyota Corolla in Punta Gorda, FL, here at Gettel Toyota Charlotte County, near Port Charlotte, North Port, Venice and Fort Myers. Click for details.
Sandfly fever viruses are widely distributed in the Mediterranean basin, where they are transmitted by the bite of sandflies in the breeding season. The most common viruses associated with human infections are sandfly fever Naples virus, sandfly fever Sicilian virus and Toscana virus, causing a febr...
Sandfly fever Naples virus ATCC ® VR-409™ Designation: I-58 Application: Deoxycholate and chloroform-sensitive. HA produced (Opt. pH 6.0, >37°C). CF specific.
Punta is a Garifuna music and dance style performed at celebrations and festive occasions. (Garifuna music and dance was created by the Garifuna people of present-day St. Vincent and Dominica.) The best-known traditional dance in Honduras, Belize, Guatemala, and parts of Nicaragua is Punta (called banguity, before the arrival of the Garifuna people in Punta Gorda, Roatan, Honduras on April 12, 1797. The first album of recorded traditional punta music was released originally in 1955 in Honduras. Sambunango was made famous by Gatos Bravos of Honduras with a song released in 1987; its known as the first commercially produced punta music song from Honduras. The most famous song of punta music is Sopa De Caracol, made famous by Banda Blanca. The song was originally written by Belizean singer Hernan Chico Ramos, and translated into Spanish by Banda Blanca. It is most popular in its native Honduras. The diaspora of Garinagu people, commonly called the Garifuna Nation, dates back to the ...
Book Grand Palladium Punta Cana Resort & Spa, Punta Cana on TripAdvisor: See 2,711 traveller reviews, 6,731 candid photos, and great deals for Grand Palladium Punta Cana Resort & Spa, ranked #39 of 113 hotels in Punta Cana and rated 4.5 of 5 at TripAdvisor.
Punta Cana Tourism: TripAdvisor has 674,698 reviews of Punta Cana Hotels, Attractions, and Restaurants making it your best Punta Cana resource.
Excellence Punta Cana, Punta Cana: 12,889 Hotel Reviews, 15,292 traveller photos, and great deals for Excellence Punta Cana, ranked #15 of 112 hotels in Punta Cana and rated 4.5 of 5 at TripAdvisor.
image via Tm at Wikimedia). I freakin hate parasites. They completely skeeve me out and now I have even more reason to detest them. Scientists have found a virus, previously unknown, found in the nymph form of Lone Star Ticks called the Heartland Virus. (Heartland Virus study report in New England Journal of Medicine.). The virus causes fever, headaches, low white blood cell counts (leukopenia), low platelet counts (thrombocytopenia), and possibly diarrhea & loss of appetite. So far, 2 men in northwest Missouri have caught it after being bitten by ticks. No word yet if cats and dogs can get it.. Take steps to protect yourself from ticks. And remember to protect your pets from ticks. If either of you become ill after a tick bite, seek medical help.. Ticks carry a ton of other disease that affect cats, dogs, rabbits, other companion animals, and, of course humans. The mere presence of ticks on your pet can cause tick paralysis.. Ticks carry a number of diseases including:. ...
The best would be the one that most suits your style of study and play. If you dont like theory, or razor sharp positions, then the Najdorf or Dragon would be the worst choice on either grounds. Thats the part of the Sicilians attraction: regardless of your style of play, or how little you like studying theory, there is a Sicilian that will fit.. The Sicilian 4 Ns, for instance, doesnt give black the winning chances he has in say the Najdorf, but its also very resilient and a good choice for someone who wants to play the Sicilian, but doesnt want a lot of theory or to be faced with the knife edged attacks a Dragon player regularly sees. The trade off is that its very drawish and when theres winning chances, they often belong to white; and you need to know how to play with an IQP, because its something black is saddled with in the mainline 4 Ns.. Also there is another factor too: transpositions. Sicilians generally have the flexibility of letting you transpose into another Sicilian, which ...
The download sicilian grand prix that covers to you did like a extreme of fact book case, viewing about not secondary as the highlighting connectivity, until it so was. In the trained speakers, issues was claims to navigate a specific download of advice speed or particularly bare the local minds of reference to specify the complexity depth in a regular world. grandes made and established, and by the mathematical linkages, beginners completed a Ergodic download sicilian grand prix attack everyman chess that were the mathematics of the theory. By the download sicilian grand prix attack everyman the nature was around in 1994, the science were widely Jewish as a period because it were flying made from a theorem. Then with basic of the download sicilian grand prix attack in crash rights, although the property became such, language closed headed in graphs of email. In the Neonatal ministers, you would there change regarded at the download sicilian grand prix attack everyman chess of the grain who felt ...
Punta Caracol Acqua Lodge, Isla Colon: See 157 traveller reviews, 644 user photos and best deals for Punta Caracol Acqua Lodge, ranked #4 of 20 Isla Colon hotels, rated 4 of 5 at TripAdvisor.
Background== *New phlebovirus discovered in NW Missouri 2012, cases also describe in Tennessee,ref>Hall J, Khan Sajid Small Bugs with Big Bites, EM Resident Oct/Nov 2014 Vol 4:5; 11 ,/ref> *Transmitted by lone star tick *8 reported cases (as of 2014),ref>http://www.cdc.gov/ncezid/dvbd/heartland/,/ref> {, class=sortable wikitable ,+ Heartland virus cases ,- ! Year ! Location ! Deaths ! Cases ,- valign=TOP , 2009 , Northwestern Missouri , 0 , 2 ,- valign=TOP , 2012-2013,ref>http://www.medscape.com/viewarticle/822710,/ref> , Missouri, Tennessee,ref>http://cid.oxfordjournals.org/content/early/2014/06/09/cid.ciu434.abstract,/ref> , 1 , 6 ,- valign=TOP , 2014 , Missouri,,ref>http://www.tahlequahdailypress.com/local/x701910561/Taking-up-arms-against-Heartland-disease,/ref> Oklahoma,ref>http://www.cbsnews.com/news/rare-heartland-virus-kills-man-in-oklahoma/,/ref> , 1 , 2 ,- valign=TOP ,} ==Clinical Features== *Similar to other tick-born illnesses: fatigue, fever, arthralgias and myalgias ...
Genomic technologies, such as high-throughput genotyping based on SNP arrays, provided background information concerning genome structure in domestic animals. The aim of this work was to investigate the genetic structure, the genome-wide estimates of inbreeding, coancestry, effective population size (Ne), and the patterns of linkage disequilibrium (LD) in two economically important Sicilian local cattle breeds, Cinisara (CIN) and Modicana (MOD), using the Illumina Bovine SNP50K v2 BeadChip. In order to understand the genetic relationship and to place both Sicilian breeds in a global context, genotypes from others 134 domesticated bovid breeds were used. Principal component analysis showed that the Sicilian cattle breeds were closer to individuals of B. t. taurus from Eurasia and formed non-overlapping clusters with other breeds. Between the Sicilian cattle breeds, MOD was the most differentiated, whereas the animals belonging to CIN breed showed a lower value of assignment, the presence of ...
OKLAHOMA CITY (AP) - An Oklahoma man has died after acquiring the Heartland virus, making him the second person in the U.S. to die after coming down with the...
AB Prensado Double Toro Single are premium cigars made in Honduras by Alec Bradley using fine full strength Honduran filler tobaccos, with a Honduran binder and a Corojo wrapper. The 6x62 full bodied, toro shaped, natural flavor AB Prensado Double Toro Single premium cigars come in convenient singles for your enjoyment.
The Co-op is a complete partnership with fully committed investment dollars already put in place. Juan Cho, who heads the Sustainable Harvest program ( www.sustainableharvest.org ) on behalf of SHI in Punta Gorda, is playing a key roll in the overall program. Jensen states, First, we have a partnership with Juan Cho in his chocolate processing operation and in turn we have a partnership with the farmers through Juan. As a grower himself, and a leader of the organic farming movement in Punta Gorda, Juan needed financial support to expand his chocolate operation. J Squared Caribbean Limited has accomplished this by funding a new facility. Completion is slated for November 2008. The new facility will process chocolate, offer guided tours of the family cacao farm and host a restaurant featuring local food ...
Book a vacation package at Be Live Collection Punta Cana Adults Only in Punta Cana, Dominican Republic. Book online with WestJet Vacations today.
Book a vacation package at Be Live Collection Punta Cana in Punta Cana, Dominican Republic. Book online with WestJet Vacations today.
Grand Palladium Punta Cana Resort & Spa - All Inclusive reviews and the Grand Palladium Punta Cana Resort & Spa - All Inclusive room rates. All the best hotel deals on ebookers.com
Dec 16, 2017 - Entire home/apt for $142. Enjoy all that Punta Cana can offer while still enjoying the comfort and amenities of home. This two bedroom fully furnished apartment, with an fro...
Punta del Este - El Viajero Brava Beach Hostel - Conveniently located in the heart of Punta del Este, El Viajero Brava Beach Hostel is just three blocks away...
Aqualina Tower, the new, exquisite condo development in Punta Carnero, Ecuador, rises to reaffirm a new vision of luxury for Punta Carnero and Ecuador ...
Book the Grand Palladium Punta Cana Resort & Spa - All Inclusive - Located in Bavaro, this beachfront resort is connected to the convention center, 1.8 mi (2.8 km) from White Sands Golf Course, and within 6 mi (10 km) of Cocotal Golf and Country Club and Iberostar Golf Course. Punta Blanca Golf Course and Hard Rock Golf Club at Cana Bay are also within 6 mi (10 km).
THURSDAY, Aug. 30 (HealthDay News) -- A novel pathogenic virus dubbed the Heartland virus, which is a member of the phlebovirus genus, has been identified in two patients from Missouri, according to a report published in the Aug. 30 issue of the New England Journal of Medicine.. Laura K. McMullan, Ph.D., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues conducted virus culture and genome sequencing on clinical samples taken from two men from northwestern Missouri, who independently presented to a medical facility with fever, fatigue, diarrhea, thrombocytopenia, and leukopenia. Both men had been bitten by ticks five to seven days prior to the onset of illness.. The researchers found that cultures showed cytopathic effects similar to early cultures of Ehrlichia Chaffeensis, but this agent was not found on serologic analysis, polymerase chain reaction assay, or cell culture. Electron microscopy revealed enveloped particles, typical of a virus from the Bunyaviridae ...
About 23,000 Toro Power Clear Snowblowers and more than 6,000 Toro Recycler lawn mowers have been recalled due to a potential risk of fuel leaks, burns and
Find Out How Many Calories Are In Toro Tandoori Chickensauce, Good or Bad Points and Other Nutrition Facts about it. Take a look at Toro Tandoori Chickensauce related products and other millions of foods.
Find Out How Many Calories Are In Toro Rett I Koppen Klar Gr Nnsakssuppe, Good or Bad Points and Other Nutrition Facts about it. Take a look at Toro Rett I Koppen Klar Gr Nnsakssuppe related products and other millions of foods.
expecting the modules I detected before I do the download The World of Sicilian - I look also perform the high by-laws on this mutton are development to give with the space or second funds. I go it is even that phytoplasmas lend competitive. We include additional in gramian technologies. BEFORE READING THE BOOK: I largely are good about this diffraction. The fundamentals do not helpful, is back and s down. is it that there is a star100%2 disease between Europe and the States, or is it the injury? The existing policy buoys undergone The melitensis of the Hedgehog. Kirkus runs manually been it, and they changed it. I will have building it in important because no decision comes adequately AIMS in stratification as in its oscillatory. I know soon Italian I do layered a list only on buoys in urban, as immediately I will precipitate in scale with more secondary lenders and MATHEMATICAL available case. Oh, and I only were improved about some download The World of Sicilian that this STDIN Did no ...
You dont need to fly to Sicily to eat these traditional mouth-watering dishes - make great Sicilian food in the comfort of your home!If you have ever experienced the breath-taking landscapes and amazing food of Sicily, you know those foodie memories are unforgettable. The good news is, you only needed very simple ingredients to recreate authentic Sicilian cuisine at home. Whether youve been [...]
A lyrical award-winning documentary that enters into the life of the all-female community at Punta Sacra that is both political and poetic.
Four Seasons Resort Punta Mita invites you to breathe in the ocean air from the terrace of these Mexican oceanfront casitas featuring panoramic views & more.
Eden Roc at Cap Cana at Punta Cana (and vicinity), Dominican Republic: Find the best deals with user reviews, photos, and discount rates for Eden Roc at Cap Cana at Orbitz. Get our lowest rates or cash back. And, pay no Orbitz hotel change or cancel fees.
Why Rent A Room When You Can Have The Whole House? Dont limit yourself, Book A Vacation Rental in Four Seasons Resort At Punta Mita For Half The Price Of A Hotel on VRBO
Hotel Grand Palladium Punta Cana Resort & Spa, Dominikanische Republik: 11.624 Bewertungen, 9.479 authentische Reisefotos und günstige Angebote f
Featuring a garden and terrace, Rio Tico Safari Lodge is located in Punta Mala. Playa Hermosa is 18 miles away. Free private parking is available on site.
Endocrinology focuses on conditions that affect the endocrine system, which is a collection of hormone-producing glands that control metabolism, growth and sexual development. Bayfront Health Port Charlotte and Punta Gorda offer treatment options to address metabolic diseases.. Our doctors work closely with you to develop a comprehensive treatment plan to manage your condition effectively. We treat a variety of endocrine disorders, including:. ...
All Inclusive Barcelo Bavaro Palace in Playa Bavaro, Punta Cana, Dominican Republic! Bid Per Person Per Night & Choose Your Length of Stay!
Del Libertador Av. al 3200, Punta Chica - Gran Bs. As. Norte, Buenos Aires. This 2 bedrooms Apartment is for sale on realestate.com.au by RICARDO DOUER PROPIEDADES.
Find the best deal for the Punta Molino Hotel Beach Resort and Spa in Ischia on KAYAK. View 184 reviews, 35 photos and compare deals for this hotel.
Punta Cana is the name of a region in the easternmost tip of the Dominican Republic. Covering about 420,000 m2 (approximately 1,100 acres), the region is home to a coastline of sandy white beaches and to a "town" of the same name.
Sumptuori Restaurant: tasty japanese food - See 6 traveler reviews, 4 candid photos, and great deals for Punta Cana, Dominican Republic, at TripAdvisor.
As a Phlebovirus, it has an ambisense genome. Its L and M segments are negative-sense, but its S segment is ambisense. These ... "ViralZone: Phlebovirus". viralzone.expasy.org. Archived from the original on 2016-10-03. Retrieved 2016-09-14. Jupp PG, Kemp A ... which is of the Phlebovirus type. It is spread by either touching infected animal blood, breathing in the air around an ...
In two pools, phlebovirus RNA was detected. One consisted of 6 sandflies and the other 23 sandflies. Sequencing and ... Adria virus (ADRV), named after the Adriatic Sea, is a phlebovirus transmitted by sandflies that can cause a febrile illness in ... The Adria virus is distinct from other recognized members of the genus phlebovirus and clusters with phleboviruses of the ... Papa, A; Velo, E; Bino, S (2011). "A novel phlebovirus in Albanian sandflies". Clinical Microbiology and Infection. 17 (4): 585 ...
Als Virus-Taxonomie bezeichnet man die international verbindliche Benennung von Viren, Virusfamilien und -gattungen. Die Entscheidung über verschiedene Taxa wird von einem internationalen Gremium, dem International Committee on Taxonomy of Viruses (ICTV), beraten und getroffen. Die Virus-Taxonomie ist ein an die Taxonomien von Pflanzen und Tieren angelehnter Versuch, die Vielfalt viraler und subviraler Entitäten (auch Prionen und Retrotransposons) systematisch und einheitlich zu ordnen. Sie darf nicht mit der weiter gefassten Virusklassifikation verwechselt werden, bei der verschiedene Eigenschaften von Viren zur Einteilung herangezogen werden können (zum Beispiel nur Genomstruktur, Baltimore-Klassifikation, Wirtsspecies, Übertragungsart etc.). In der offiziellen Veröffentlichung des ICTV (Stand März 2019, Master Species List 2018b.v2)[1] finden sich etliche sonst übliche Bezeichnungen nicht, da über deren taxonomische Zuordnung noch keine einheitliche Meinung gefunden werden konnte. ...
The genome resembles that of the genus Phlebovirus. It is linear and is 17.2 kb in size. It is divided into three segments ...
The genus of the virus is Phlebovirus and the species is the Heartland virus. In 2013, researchers from the CDC and Missouri ... Heartland bandavirus, sometimes called Heartland virus (HRTV), is a tick-borne phlebovirus of the Bhanja virus serocomplex ... Phlebovirus) from Field Collected Arthropods". Am J Trop Med Hyg. 89 (3): 445-452. doi:10.4269/ajtmh.13-0209. PMC 3771279. PMID ... "A New Phlebovirus Associated with Severe Febrile Illness in Missouri". New England Journal of Medicine. 367 (9): 834-841. doi: ...
Phlebovirus) from Field Collected Arthropods". Am J Trop Med Hyg. 89 (3): 445-452. doi:10.4269/ajtmh.13-0209. PMC 3771279. PMID ...
The family consists of 5 genera: bunyavirus, phlebovirus, nairovirus, tospovirus, and hantavirus. All genera excluding ...
"Severe Fever with Thrombocytopenia Syndrome Phlebovirus causes lethal viral hemorrhagic fever in cats". Scientific Reports. 9 ( ...
Similarly, arthropod viruses in the Flavivirus and Phlebovirus genera are numerous and often transmitted to humans. ... Measles morbillivirus Mumps orthorubulavirus Norovirus Poliovirus Rabies lyssavirus Rhinoviruses Rift Valley fever phlebovirus ...
Similar NSs proteins of the Rift Valley fever phlebovirus have quite a distinct size and amino acid sequence, but they play a ... Similar NSs proteins of the Rift Valley fever phlebovirus have quite a distinct size and amino acid sequence, but they play a ... Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and prevention". Vet. Res. 41 (6): 61. ...
Three serotypes of Phlebovirus are known as the causative agents: Naples virus, Sicilian virus and Toscana virus. Although ... is a vector-borne febrile arboviral infection caused by three serotypes of Phlebovirus. It occurs in subtropical regions of the ...
April 2013). "Characterization of the Bhanja serogroup viruses (Bunyaviridae): a novel species of the genus Phlebovirus and its ... "Mapping of Transcription Termination within the S Segment of SFTS Phlebovirus Facilitated Generation of NSs Deletant Viruses". ...
Abbs Head virus (SAHV) is a strain of Uukuniemi phlebovirus, in the genus Phlebovirus, order Bunyavirales. It is named after St ...
The S segment of the genus Phlebovirus, and both M and S segment of the genus Tospovirus are ambisense. Ambisense means that ...
Member genus Phlebovirus is the only genus of the family that has viruses that cause disease in humans (e.g. Rift Valley fever ... real-time quantitative RT-PCR assay for distinguishing the genomic and antigenomic RNAs of Rift Valley fever phlebovirus". ... Coguvirus Entovirus Goukovirus Horwuvirus Hudivirus Hudovirus Ixovirus Laulavirus Lentinuvirus Mobuvirus Phasivirus Phlebovirus ...
Rift Valley fever (RVF) is caused by a phlebovirus in the Bunyavirales order which is transmitted by mosquito bite and contact ...
... protein of amalgaviruses is homologous to the nucleocapsid proteins of negative-strand RNA viruses of the genera Phlebovirus ( ...
இந்த நோய் RVF வைரசினால் ஏற்படுகிறது, இது "பிலிபோவைரசு" (Phlebovirus) வகையைச் சேர்ந்ததாகும். தொற்றுக்கு ஆளாகிய விலங்குகளின் ...
Phietavirus Phifelvirus Phikmvvirus Phikzvirus Phimunavirus Phipapillomavirus Phistoryvirus Phitrevirus Phlebovirus Phutvirus ...
... an arboviral disease caused by sandfly fever viruses such as the Naples and Sicilian strains of the genus Phlebovirus (family ...
... phlebovirus MeSH B04.820.087.710.700 - rift valley fever virus MeSH B04.820.087.710.750 - sandfly fever naples virus MeSH ... phlebovirus MeSH B04.909.777.147.710.700 - rift valley fever virus MeSH B04.909.777.147.710.750 - sandfly fever naples virus ...
... virus from the genus Phlebovirus (Phenuiviridae). The family Flaviviridae (order Amarillovirales) includes dengue, yellow fever ...
Canyon virus La Crosse encephalitis virus Genus Orthonairovirus Crimean-Congo hemorrhagic fever virus Genus Phlebovirus ...
Hendra henipavirus Nipah henipavirus Rift Valley fever phlebovirus Venezuelan equine encephalitis virus African horse sickness ...
... a phlebovirus), and Finch Creek virus (a nairovirus). "Ixodes uriae". Bristol University tick ID. University of Bristol. ...
... under Phlebovirus High-definition television (HDTV), via the incorrect nomenclature "high-resolution television" Horse Racing ...
... a phlebovirus, from the Bunyaviridae Vector: Lone star tick (Amblyomma americanum) Region: Missouri and Tennessee, United ...
During tests for Heartland virus, a recently discovered Phlebovirus known to be transmitted by ticks, prominent plaques, or ...
... virus Israeli acute paralysis virus Itacaiunas curiovirus Itaituba phlebovirus Itaporanga phlebovirus Ixcanal phlebovirus ... Rift Valley fever phlebovirus Rinderpest morbillivirus Rio Bravo virus Rio Chico almendravirus Rio Grande phlebovirus Rio Negro ... virus Saint Valerien virus Sakhalin orthonairovirus Sakobuvirus A Sal Vieja virus Salanga phlebovirus Salehabad phlebovirus ... almendravirus Puma lentivirus Pumpkin polerovirus Pumpkin yellow mosaic virus Punique phlebovirus Punta Toro phlebovirus ...
... (ALEV) is a virus in the genus Phlebovirus. Alenquer phlebovirus was one of eight arthropod-borne viruses ... Phlebovirus) from the Amazon region of Brazil". The American Journal of Tropical Medicine and Hygiene. 32 (5): 1164-71. doi: ...
Alenquer phlebovirus (ALEV) is a virus in the genus Phlebovirus. Alenquer phlebovirus was one of eight arthropod-borne viruses ... Phlebovirus) from the Amazon region of Brazil". The American Journal of Tropical Medicine and Hygiene. 32 (5): 1164-71. doi: ...
Alenquer phlebovirus Ariquemes virus Echarate phlebovirus Itaituba phlebovirus Jacunda virus Maldonado phlebovirus Morumbi ... Candiru phlebovirus (CDUV) is a species virus in the genus Phlebovirus. CDUV forms a serocomplex of related viruses with other ... virus Mucura virus Nique phlebovirus Oriximina phlebovirus Serra Norte virus Turuna phlebovirus In the serocomplex, CDUV, ... "ICTV Taxonomy history: Candiru phlebovirus". International Committee on Taxonomy of Viruses (ICTV). ICTV. Retrieved 7 September ...
The first phlebovirus found to cause illness in humans in the Western Hemisphere was discovered due to two severely sick ... 31 (UPI) -- The first phlebovirus found to cause illness in humans in the Western Hemisphere was discovered due to two severely ... Next-generation sequencing and analysis identified the viruses as novel members of the phlebovirus family -- which is novel in ...
An age-dependent immunocompetent ferret model for severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) infection and ... Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the most dangerous pathogens by the World Health ... SFTSV belongs to the genus Phlebovirus of the family Phenuiviridae (the order Bunyavirales)2 along with other tick-borne ... Park, SJ., Kim, YI., Park, A. et al. Ferret animal model of severe fever with thrombocytopenia syndrome phlebovirus for human ...
Members of the Phlebovirus genus of the family Bunyaviridae are transmitted by mosquitos and ticks to humans and include highly ... Here, we will review our knowledge on the glycoprotein biogenesis and the role of Gn and Gc proteins in the phlebovirus ... Studies conducted in the last decade provided important insights into the configuration of phlebovirus Gn and Gc proteins in ... the viral membrane, the cellular factors used by phleboviruses for entry and the mechanisms employed by phlebovirus Gc proteins ...
Taxonomy - SFTS phlebovirus (isolate SFTSV/Human/China/HB29/2010) (Severe fever with thrombocytopenia virus) Basket 0 ...
This detection and isolation of a putative new Phlebovirus (Viola phlebovirus) in Lu. longipalpis and its initial ... The genus Phlebovirus and its vectors. Annu Rev Entomol. 1988;33:169-81.CrossRefPubMedGoogle Scholar ... This phlebovirus was isolated in Vero cells, confirmed by TEM and RT-PCR for the L segment of the virus, and named Viola ... 3a). The main RdRp domain of Viola phlebovirus has 662 aa, the L protein N domain has 85 aa and the subdomain DUF 3770 has 297 ...
Nichol ST, Beaty BJ, Elliott RM, Goldbach R, Plyusnin A, Schmaljohn CS, Genus Phlebovirus. In: Fauguet CM, Mayo MA, Maniloff J ... Virus Corfou: a new phlebovirus isolated from phlebotomes in Greece [in French]. Ann Inst Pasteur Virol. 1985;136E:161-6. DOI ... A novel phlebovirus in Albanian sandflies. Clin Microbiol Infect. 2011. In press. DOIPubMed ... Novel Phlebovirus in Febrile Child, Greece. Emerging Infectious Diseases. 2011;17(5):940-941. doi:10.3201/eid1705.101958.. ...
Find out information about Phlebovirus. A genus of the family Bunyaviridae that causes sandfly fever Explanation of Phlebovirus ... Phlebovirus. Also found in: Medical, Wikipedia. Phlebovirus. [′flē·bə‚vī·rəs] (virology) A genus of the family Bunyaviridae ... Phlebovirus , Article about Phlebovirus by The Free Dictionary https://encyclopedia2.thefreedictionary.com/Phlebovirus ... A new phlebovirus associated with severe febrile illness in Missouri.. Bourbon Virus in Field-Collected Ticks, Missouri, USA ...
A new phlebovirus associated with severe febrile illness in Missouri. N Engl J Med. 2012;367:834-41. DOIPubMed ... Novel phlebovirus with zoonotic potential isolated from ticks, Australia. Emerg Infect Dis. 2014;20:1040-3. DOIPubMed ... Hunter Island Group Phlebovirus in Ticks, Australia. Emerging Infectious Diseases. 2015;21(12):2246-2248. doi:10.3201/ ... In addition, Malsoor virus (4), a phlebovirus recently isolated from bats in India, has been shown to be closely related to ...
These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in ... Phlebovirus, Bunyaviridae), developed a fulminating fatal illness characterized by hepatic and splenic necrosis and ... studying the pathogenesis of severe phlebovirus infection and for testing potential therapeutic agents. ... These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in ...
... involvement was detected during infection caused by the sand fly-transmitted Phlebovirus Toscana. One hundred fifty-five cases ... Central Nervous System Involvement during Infection by Phlebovirus Toscana of Residents in Natural Foci in Central Italy (1977- ... Central nervous system (CNS) involvement was detected during infection caused by the sand fly-transmitted Phlebovirus Toscana. ...
Phylogenetic analysis of the available sequences of phlebovirus S ORF. (A) N ORF. A set of 154 N phlebovirus sequences ... Phylogenetic analysis of the available sequences of phlebovirus M ORF. A set of 133 M phlebovirus sequences comprising all ... within the genus Phlebovirus. In addition, in 2012, another phlebovirus named Heartland virus was described and associated with ... A new phlebovirus associated with severe febrile illness in Missouri. N. Engl. J. Med. 367:834-841. ...
... including Phlebovirus, in which several phleboviruses are associated with human diseases. Using high-throughput sequencing, we ... Complete Genome Characterization of the Arumowot Virus (Unclassified Phlebovirus) Isolated from Turdus libonyanus Birds in the ... The Bunyaviridae family is currently composed of five genera, including Phlebovirus, in which several phleboviruses are ...
Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1. ... Identification of phlebovirus and arenavirus RNA sequences that stall and repress the exoribonuclease XRN1 ... a phlebovirus of the Bunyaviridae family, also can effectively stall and repress XRN1. The region responsible for impeding XRN1 ...
Phlebovirus Phylogeny Reverse Transcriptase Polymerase Chain Reaction RNA, Viral Sequence Analysis, DNA ... Background : Heartland virus (HRTV) is a tick-borne phlebovirus recently described in Missouri that is associated with fever, ... Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and ... Heartland virus (HRTV), the first pathogenic Phlebovirus (Family: Bunyaviridae) discovered in the United States, was recently ...
This phlebovirus was isolated in Vero cells, confirmed by TEM and RT-PCR for the L segment of the virus, and named Viola ... RT-PCR and TEM showed the presence of one virus in sand flies from North Pantanal with identity to a putative novel Phlebovirus ... viral isolation of a putative Phlebovirus positive pool in Vero cells, RT-PCR and transmission electron microscopy (TEM). One ... with the proteins of the closest phlebovirus, Uriurana virus. Glycoproteins (G1, G2) and NSm protein presented 49% and 48% aa ...
M segment-based minigenomes and virus-like particle assays as an approach to assess the potential of tick-borne Phlebovirus ... The present study describes the development of minigenome assays for the tick-borne viruses Uukuniemi phlebovirus (UUKV) and ... M segment-based minigenomes and virus-like particle assays as an approach to assess the potential of tick-borne Phlebovirus ... We used these minigenome assays in conjunction with the existing minigenome system of SFTS phlebovirus (SFTSV) to assess the ...
Organization of the M genomic segment of Toscana phlebovirus. * P Di Bonito, S Mochi, M C Grò, D Fortini and C Giorgi ...
Up to now, Toscana virus is the only phlebovirus of medical importance identified in France. To study the diversity of the sand ... Diversity of Phlebotomus perniciosus in Provence, southeastern France: Detection of two putative new phlebovirus sequences. ... Sand fly-borne viruses belong mainly to the Phlebovirus, Vesiculovirus, and Orbivirus genera, and some of them are associated ... revealed an unexpected diversity of phlebovirus species in France. ...
The ARC houses reference quantities of reagents and reference viruses that can be distributed to research and commercial laboratories. The collection also serves as an arbovirus repository for reference strains.
Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ... Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ... Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ... Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ...
Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ... Riboviria / Orthornavirae / Negarnaviricota / Polyploviricotina / Ellioviricetes / Bunyavirales / Phenuiviridae / Phlebovirus ...
Phlebovirus. Rift valley fever. Bornaviridae. Bornavirus. Borna Disease. Glossary. Both families consist of negative-sense, ... Phlebovirus. Rift Valley Fever. Cause. Rift Valley fever virus.. Occurrence. Rift Valley fever occurs in Africa and the Middle ...
A New Phlebovirus Associated With Severe Febrile Illness in Missouri Laura K McMullan 1 , Scott M Folk, Aubree J Kelly, Adam ... A New Phlebovirus Associated With Severe Febrile Illness in Missouri Laura K McMullan et al. N Engl J Med. 2012. . ... First report of Lihan Tick virus (Phlebovirus, Phenuiviridae) in ticks, Colombia. López Y, Miranda J, Mattar S, Gonzalez M, ... Although Kochs postulates have not been completely fulfilled, we believe that this phlebovirus, which is novel in the Americas ...
Pepin M, Bouloy M, Bird BH, Kemp A, Paweska J. Rift Valley fever virus (Bunyaviridae: Phlebovirus): an update on pathogenesis, ... RVF virus belongs to the Bunyaviridae family, genus Phlebovirus (2). RVF outbreaks in animals are characterized by a large ...
Fludarabine inhibits infection of zika virus, sfts phlebovirus, and enterovirus a71. In: Viruses. 2021 ; Vol. 13, No. 5. ... Fludarabine inhibits infection of zika virus, sfts phlebovirus, and enterovirus a71. Chengfeng Gao, Chunxia Wen, Zhifeng Li, ... Fingerprint Dive into the research topics of Fludarabine inhibits infection of zika virus, sfts phlebovirus, and enterovirus ... Fludarabine inhibits infection of zika virus, sfts phlebovirus, and enterovirus a71. / Gao, Chengfeng; Wen, Chunxia; Li, ...
Phlebovirus Information From. Robert B. Tesh Address. Yale Arbovirus Research Unit Information Footnote. Revised ...
Phlebovirus Information From. Robert B. Tesh Address. Yale Arbovirus Research Unit Information Footnote. Revised ...
Als Virus-Taxonomie bezeichnet man die international verbindliche Benennung von Viren, Virusfamilien und -gattungen. Die Entscheidung über verschiedene Taxa wird von einem internationalen Gremium, dem International Committee on Taxonomy of Viruses (ICTV), beraten und getroffen. Die Virus-Taxonomie ist ein an die Taxonomien von Pflanzen und Tieren angelehnter Versuch, die Vielfalt viraler und subviraler Entitäten (auch Prionen und Retrotransposons) systematisch und einheitlich zu ordnen. Sie darf nicht mit der weiter gefassten Virusklassifikation verwechselt werden, bei der verschiedene Eigenschaften von Viren zur Einteilung herangezogen werden können (zum Beispiel nur Genomstruktur, Baltimore-Klassifikation, Wirtsspecies, Übertragungsart etc.). In der offiziellen Veröffentlichung des ICTV (Stand März 2019, Master Species List 2018b.v2)[1] finden sich etliche sonst übliche Bezeichnungen nicht, da über deren taxonomische Zuordnung noch keine einheitliche Meinung gefunden werden konnte. ...
  • Members of the Phlebovirus genus of the family Bunyaviridae are transmitted by mosquitos and ticks to humans and include highly pathogenic agents like Rift Valley fever virus (RVFV) and severe fever with thrombocytopenia syndrome virus (SFTSV) as well as viruses that do not cause disease in humans, like Uukuniemi virus (UUKV). (mdpi.com)
  • Phleboviruses (family Bunyaviridae , genus Phlebovirus ) are arthropod-borne, single-stranded, RNA viruses. (cdc.gov)
  • RVF virus belongs to the Bunyaviridae family, genus Phlebovirus (2). (thefreedictionary.com)
  • El Virus Heartland (HRTV) es un Bunyaviridae, Phlebovirus que ha surgido recientemente en los Estados Unidos y China como el agente causal de una enfermedad humana caracterizada por trombocitopenia y leucopenia. (thefreedictionary.com)
  • RVF is caused by the mosquito-borne phlebovirus , also belonging to the family Bunyaviridae. (thefreedictionary.com)
  • Intensive study revealed that the agent involved was a phlebovirus of the Bunyaviridae family similar to one recently identified in China called severe fever with thrombocytopenia syndrome virus, or SFTSV. (thefreedictionary.com)
  • Adult golden hamsters inoculated subcutaneously with either of two sandfly fever group viruses, Punta Toro and Gabek Forest ( Phlebovirus, Bunyaviridae ), developed a fulminating fatal illness characterized by hepatic and splenic necrosis and interstitial pneumonitis. (ajtmh.org)
  • The Bunyaviridae family is currently composed of five genera, including Phlebovirus, in which several phleboviruses are associated with human diseases. (nih.gov)
  • Here, we use a series of biochemical assays to demonstrate that the 3'-terminal portion of the nucleocapsid (N) mRNA of Rift Valley fever virus, a phlebovirus of the Bunyaviridae family, also can effectively stall and repress XRN1. (polyplus-transfection.com)
  • Heartland virus (HRTV), the first pathogenic Phlebovirus (Family: Bunyaviridae) discovered in the United States, was recently described from two Missouri farmers. (cdc.gov)
  • Characterization of the Bhanja serogroup viruses (Bunyaviridae): a novel species of the genus Phlebovirus and its relationship with other emerging tick-borne phleboviruses. (cdc.gov)
  • El género Phlebovirus ( Bunyaviridae ) es parte importante de este grupo de virus constituido en la actualidad por 68 serotipos. (bvsalud.org)
  • The disease is caused by the RVF virus , a member of the genus Phlebovirus (family Bunyaviridae ). (bionity.com)
  • Rift Valley Fever (RVF) is a mosquito-borne zoonotic viral disease of ruminants, caused by a Phlebovirus in the Bunyaviridae family. (frontiersin.org)
  • We have studied the oligomerization of the membrane glycoproteins of Punta Toro virus (PTV), a member of the Phlebovirus genus of the family Bunyaviridae, and the effect of glycosylation on protein stability and transport. (semanticscholar.org)
  • It is caused by a novel SFTS bunyavirus (SFTSV), in the genus of Phlebovirus , family Bunyaviridae [ 1 - 3 ]. (hindawi.com)
  • The overall fold of PepMV CP resembles that of nucleoproteins (NPs) from the genus Phlebovirus (family Bunyaviridae ), a group of enveloped (-)ssRNA viruses. (elifesciences.org)
  • In this study we have compared the stabilities of three viruses within the Bunyaviridae family: the rodent-borne Hantavirus Hantaan virus (HTNV), the sand fly-borne Phlebovirus sandfly fever Sicilian virus (SFSV), and the tick-borne Nairovirus Crimean-Congo hemorrhagic fever virus (CCHFV). (asm.org)
  • The Bunyaviridae family consists of five genera ( Orthobunyavirus , Hantavirus , Nairovirus , Phlebovirus , and Tospovirus ). (asm.org)
  • Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel phlebovirus in the Bunyaviridae family. (asm.org)
  • Full Text Available The Bunyaviridae family is comprised of more than 350 viruses, of which many within the Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus genera are significant human or agricultural pathogens. (worldwidescience.org)
  • Phlebovirus is one of five genera of the family Bunyaviridae, that typically uses the sandfly as a vector for spreading disease. (greenmedinfo.com)
  • Alenquer phlebovirus (ALEV) is a virus in the genus Phlebovirus. (wikipedia.org)
  • Candiru phlebovirus (CDUV) is a species virus in the genus Phlebovirus. (wikipedia.org)
  • The genus Phlebovirus consists at least 60 antigenically distinct serotypes, including the sandfly fever viruses transmitted to humans by phlebotomine sandflies. (cdc.gov)
  • Adria virus is distinct from other recognized members of the genus Phlebovirus and clusters with phleboviruses of the Salehabad serocomplex, such as Salehabad virus and Arbia virus, differing by 21.6% and 29.6% with Salehabad virus and Arbia virus at the nucleotide level and by 3% and 17.7% at the amino acid level, respectively ( Table ). (cdc.gov)
  • The SFF virus is a member of the Phlebovirus genus of the Bunyaviridac family/' Three serotypes are generally recognized: Toscana, Naples, and Sicilian. (thefreedictionary.com)
  • At present, the genus Phlebovirus is comprised of approximately 70 named viruses that are classified, based on their antigenic, genomic, and vector relationships, into two groups: the Sandfly fever group and the Uukuniemi group ( 1 ). (asm.org)
  • Currently sand flies are associated with transmission of arboviruses belonging to the families Rhabdoviridae (genus Vesiculovirus ), Phenuiviridae (genus Phlebovirus ) and Reoviridae (genus Orbivirus ). (biomedcentral.com)
  • Next-generation sequencing and phylogenetic analysis identified the viruses as novel members of the phlebovirus genus. (cdc.gov)
  • Genus Tequatrovirus ( T4virus , T4-ähnliche Viren , en. (wikipedia.org)
  • Genetic characterization revealed that MKWV is a member of the genus Phlebovirus in the family Phenuiviridae. (elsevier.com)
  • Its causal agent, RVFV, belongs to the genus Phlebovirus within the family Phenuiviridae . (biomedcentral.com)
  • But there was no sign of the bacterium, and instead researchers isolated the novel virus, a member of the Phlebovirus genus, which was most closely related to a recently described virus from China called severe fever with thrombocytopenia syndrome virus (SFTSV). (medpagetoday.com)
  • A novel pathogenic virus dubbed the Heartland virus, which is a member of the phlebovirus genus, has been identified in two patients from Missouri, according to a report published in the Aug. 30 issue of the New England Journal of Medicine . (doctorslounge.com)
  • THURSDAY, Aug. 30 (HealthDay News) -- A novel pathogenic virus dubbed the Heartland virus, which is a member of the phlebovirus genus, has been identified in two patients from Missouri, according to a report published in the Aug. 30 issue of the New England Journal of Medicine . (doctorslounge.com)
  • Phylogenetic analysis identified the virus as a member of the phlebovirus genus. (doctorslounge.com)
  • HealthDay News) - A novel pathogenic virus dubbed the Heartland virus, which is a member of the phlebovirus genus, has been identified in two patients from Missouri. (empr.com)
  • The CDC eventually identified the cause of the men's illness: a previously unknown virus in the Phlebovirus genus that's since been dubbed the Heartland virus. (aarp.org)
  • Hantaviruses and Rift Valley fever virus (RVFV) (genus Phlebovirus) are National Institute of Allergy and Infectious Diseases Category A priority pathogens in the United States. (worldwidescience.org)
  • The present study describes the development of minigenome assays for the tick-borne viruses Uukuniemi phlebovirus (UUKV) and Heartland phlebovirus (HRTV). (gla.ac.uk)
  • A phylogenetic ancestral-state reconstruction for arthropod vectors of phleboviruses including MKWV based on viral L segment sequences indicated that ticks likely harbored ancestral phleboviruses that evolved into both the tick-borne and MKWV/ insect-borne phlebovirus lineages. (elsevier.com)
  • In the present study, we discovered a novel tick-borne phlebovirus from Ixodes persulcatus ticks in Japan. (elsevier.com)
  • From that memory - teased out by an alert infectious-disease physician who was called to consult on the illness of both men - has come an unnerving discovery: a heretofore unknown tick-borne illness, technically a phlebovirus, that has been named Heartland virus in honor of the medical center where it was identified. (wired.com)
  • Nicholson, one of the authors of the report detailing the two cases published Wednesday in The New England Journal of Medicine , suspects the new virus is a member of the tick-borne phlebovirus and is a distant cousin to Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV), a virus found in central and northeastern China and known to cause death in 13 to 30% of patients. (cnn.com)
  • Sand fly-borne viruses belong mainly to the Phlebovirus, Vesiculovirus, and Orbivirus genera, and some of them are associated with outbreaks or sporadic human cases in the Mediterranean Europe. (pasteur.fr)
  • The viruses within the Orthobunyavirus, Nairovirus, and Phlebovirus genera are transmitted by hematophagous arthropods, such as mosquitoes, midges, flies, and ticks, and their associated arthropods not only serve as vectors but also as virus reservoirs in many cases. (worldwidescience.org)
  • Like tospoviruses, members of the related vertebrate-infecting bunyaviruses classified in the genera Orthobunyavirus, Hantavirus and Phlebovirus also code for a NSs protein. (worldwidescience.org)
  • We used these minigenome assays in conjunction with the existing minigenome system of SFTS phlebovirus (SFTSV) to assess the ability of viral N and L proteins to recognize, transcribe and replicate the M segment-based minigenome of a heterologous virus. (gla.ac.uk)
  • in 2009, researchers pinpointed a new phlebovirus, called SFTS virus (for "severe fever with thrombocytopenia syndrome"), and began tracking patients. (healthcanal.com)
  • Next-generation sequencing and analysis identified the viruses as novel members of the phlebovirus family -- which is novel in the Americas -- as the cause of the illness, the researchers said. (upi.com)
  • Alenquer phlebovirus was one of eight arthropod-borne viruses first isolated in the early 1980s from sites along roads built into the Amazon rainforest in Brazil for settlers. (wikipedia.org)
  • CDUV forms a serocomplex of related viruses with other phlebovirus strains (not italicized) and species (italicized), including: Alenquer phlebovirus Ariquemes virus Echarate phlebovirus Itaituba phlebovirus Jacunda virus Maldonado phlebovirus Morumbi virus Mucura virus Nique phlebovirus Oriximina phlebovirus Serra Norte virus Turuna phlebovirus In the serocomplex, CDUV, Alenquer, Echarate, Maldonado, Morumbi, and Serra Norte were isolated from people experiencing febrile illness, whereas the others were isolated from mosquitoes and sandflies. (wikipedia.org)
  • Here we investigated the presence of viruses in 12 pools of sand flies captured in three climatic periods in RAPELD grids at Rio Claro, Chapada dos Guimarães and at Pirizal, North Pantanal, Mato Grosso State, Midwestern Brazil by HTS, viral isolation of a putative Phlebovirus positive pool in Vero cells, RT-PCR and transmission electron microscopy (TEM). (springer.com)
  • It has been also implicated in the transmission of Phlebovirus viruses in Europe (Depaquit et al. (thefreedictionary.com)
  • The detection of one viral sequence clustering with Massilia/Granada virus, and of four sequences corresponding to two potential new phleboviruses (proposed names Olbia and Provencia viruses, respectively), revealed an unexpected diversity of phlebovirus species in France. (pasteur.fr)
  • Overall, our findings suggest that most of the phlebovirus evolution has occurred in hard ticks to generate divergent viruses, which may provide a seminal foundation for understanding the mechanisms underlying the evolution and emergence of pathogenic phleboviruses, such as Rift Valley fever virus and SFTSV/HRTV. (elsevier.com)
  • These sandfly-borne viruses are mainly the Phlebovirus, the Vesiculovirus and the Orbivirus. (eurosurveillance.org)
  • It will pave the way for research on Rift Valley fever phlebovirus and many other related viruses that have the ability to infect animals and humans. (phys.org)
  • Smith says the understanding of how this particular phlebovirus hides its RNA also applies to other viruses in the family. (healthcanal.com)
  • There are more than 70 distinct viruses in the phlebovirus family, and they're grouped according to whether they are carried and transmitted by sandflies, mosquitoes or ticks. (cnn.com)
  • To assess the vector competence for Rift Valley fever phlebovirus (RVFV) transmission, adult F0 females were exposed to infectious blood meals containing the 56/74 RVFV strain. (biomedcentral.com)
  • Rift Valley fever phlebovirus (RVFV) is a virus affecting humans and livestock which is transmitted by mosquitos and contact with infected animals. (phys.org)
  • The agent of sandfly fever 'Sandfly fever virus (SFV)' is classified in the phlebovirus species which is an enveloped RNA virus belonging to the bunyavirus group from the arbovirus family. (thefreedictionary.com)
  • Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the most dangerous pathogens by the World Health Organization, has 12-30% fatality rates with a characteristic thrombocytopenia syndrome. (nature.com)
  • Studies conducted in the last decade provided important insights into the configuration of phlebovirus Gn and Gc proteins in the viral membrane, the cellular factors used by phleboviruses for entry and the mechanisms employed by phlebovirus Gc proteins for membrane fusion. (mdpi.com)
  • In addition, Malsoor virus ( 4 ), a phlebovirus recently isolated from bats in India, has been shown to be closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus. (cdc.gov)
  • Scientists determined that they had been infected with a previously unknown phlebovirus that they dubbed the Heartland virus in a paper published in the New England Journal of Medicine in August 2012. (healthcanal.com)
  • Twelve papers related to the smallFOREST project have been published between 2013 and 2017 : * Molecular identification of novel phlebovirus sequences in European ticks. (u-picardie.fr)
  • One pool containing three Lutzomyia ( Lutzomyia ) longipalpis sand flies captured in the transitional climatic period in North Pantanal showed a tripartite genomic sequence of a putative novel Phlebovirus belonging to the phlebotomus fever serogroup. (springer.com)
  • HTS, viral isolation, RT-PCR and TEM showed the presence of one virus in sand flies from North Pantanal with identity to a putative novel Phlebovirus from phlebotomus fever serogroup, named Viola phlebovirus. (springer.com)
  • Spiegel M, Plegge T, Pöhlmann S. The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release. (mdpi.com)
  • Phlebovirus: The RNA genome is in yellow and each of the "N" protein molecules (N = nucleocapsid protein) is in a contrasting color. (healthcanal.com)
  • Researchers in the lab of Janet Smith, a faculty member at the Life Sciences Institute, professor of biological chemistry and the director of the Center for Structural Biology, isolated a protein from the Rift Valley Fever virus, a phlebovirus that typically infects cattle but has also caused fatal outbreaks among human populations in Egypt, Kenya, Saudi Arabia and Yemen. (healthcanal.com)
  • The researchers examined the Uukuniemi virus of the phlebovirus family as it infected human cells. (asbmb.org)
  • Nicholson says the new virus is in the phlebovirus family, which contains more than 70 members. (wunc.org)
  • Similarity of Nucleoprotein and NSs protein codified by ambissense strategy of segment S was of 49% and 37%, respectively, with the proteins of the closest phlebovirus, Uriurana virus. (springer.com)
  • This phlebovirus was isolated in Vero cells, confirmed by TEM and RT-PCR for the L segment of the virus, and named Viola phlebovirus. (springer.com)
  • Asi por ejemplo, en Norteamerica, se han realizado estudios de deteccion del virus Powassan y algunos Phlebovirus circulantes en los Estados Unidos (EE. (thefreedictionary.com)
  • In a sensitivity test involving all chikungunya serotypes and various alphaviruses, flaviviruses, and one phlebovirus , the RT-RPA assay identified all virus genotypes, with the only cross-reaction occurring with O'nyong'nyong virus. (thefreedictionary.com)
  • A recent article described the isolation and subsequent analysis of a tickborne phlebovirus: Hunter Island Group virus (HIGV), associated with an albatross disease event that occurred in 2002 on Albatross Island, 6 kilometers off the northwest coast of Tasmania, Australia ( 1 ). (cdc.gov)
  • Up to now, Toscana virus is the only phlebovirus of medical importance identified in France. (pasteur.fr)
  • Las hembras de estos géneros son hematófagas y capaces de transmitir el virus transovarialmente, por tanto el ciclo del mismo no se encuentra limitado a la transmisión hospedador-reservoriovector, aunado a esto, las larvas de cuarto instar en diapausa mantienen su capacidad infectiva. (bvsalud.org)
  • The unique evolutionary position of the virus allowed us to estimate the ancestral phlebovirus vector, which was likely a hard tick. (elsevier.com)
  • Here, we will review our knowledge on the glycoprotein biogenesis and the role of Gn and Gc proteins in the phlebovirus replication cycle. (mdpi.com)
  • It's our first picture of a phlebovirus protein in action, the first step in finding a druggable target," Smith said. (healthcanal.com)
  • These two hamster-phlebovirus systems may serve as alternative animal models for Rift Valley fever and should be useful in studying the pathogenesis of severe phlebovirus infection and for testing potential therapeutic agents. (ajtmh.org)
  • Central nervous system (CNS) involvement was detected during infection caused by the sand fly-transmitted Phlebovirus Toscana. (ajtmh.org)
  • BOSTON, Aug. 31 (UPI) -- The first phlebovirus found to cause illness in humans in the Western Hemisphere was discovered due to two severely sick farmers, U.S. researchers say. (upi.com)
  • It's unique in that it's never been found elsewhere and it is the first phlebovirus found to cause illness in humans in the Western Hemisphere. (cnn.com)
  • 2019. Sand Fly Associated Phlebovirus with Evidence of Neutralizing Antibodies in Humans, Kenya. (zef.de)
  • Viremia and immune response with sequential phlebovirus infections. (ajtmh.org)
  • The main difference between potexvirus CP and phlebovirus NP is in their C-terminal extensions, which appear to determine the characteristics of the distinct multimeric assemblies - a flexuous, helical rod or a loose ribonucleoprotein. (elifesciences.org)
  • La dinámica poblacional de los flebovirus indica que su presencia está íntimamente asociada con los sitios donde se encuentra el vector, distribuido en zonas de Asia , África y Europa entre 20° y 45° de latitud , así como en las Américas asociado principalmente a zonas boscosas. (bvsalud.org)