An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mainly trees and shrubs. Many members contain mucilage and COUMARINS.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)
A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell, especially a fluid containing fragrant natural oils extracted from flowers, woods, etc., or similar synthetic oils. (Random House Unabridged Dictionary, 2d ed)
Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.
Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.
Formal instruction, learning, or training in the preparation, dispensing, and proper utilization of drugs in the field of medicine.
Individuals enrolled in a school of pharmacy or a formal educational program leading to a degree in pharmacy.
An ascomycetous yeast of the fungal family Saccharomycetaceae, order SACCHAROMYCETALES.
A nutritious food consisting primarily of the curd or the semisolid substance formed when milk coagulates.
A genus known for fibers obtained from their leaves: sisal from A. sisalana, henequen from A. fourcroyoides and A. cantala, or Manila-Maguey fiber from A. cantala. Some species provide a sap that is fermented to an intoxicating drink, called pulque in Mexico. Some contain agavesides.
A plant genus in the family LILIACEAE (sometimes placed in Asparagaceae) that contains ECDYSTEROIDS and is an ingredient of Siotone. The shoots are used as a vegetable and the roots are used in FOLK MEDICINE.
The volatile portions of substances perceptible by the sense of smell. (Grant & Hackh's Chemical Dictionary, 5th ed)
An offensive, foul breath odor resulting from a variety of causes such as poor oral hygiene, dental or oral infections, or the ingestion of certain foods.
Exclusive legal rights or privileges applied to inventions, plants, etc.
The ability to detect scents or odors, such as the function of OLFACTORY RECEPTOR NEURONS.
Inorganic or organic compounds that contain sulfur as an integral part of the molecule.
Isomeric forms and derivatives of hexanol (C6H11OH).
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
Procedures that render the female sterile by interrupting the flow in the FALLOPIAN TUBE. These procedures generally are surgical, and may also use chemicals or physical means.
Procedures to block or remove all or part of the genital tract for the purpose of rendering individuals sterile, incapable of reproduction. Surgical sterilization procedures are the most commonly used. There are also sterilization procedures involving chemical or physical means.
Excision of the uterus.
Procedures to reverse the effect of REPRODUCTIVE STERILIZATION and to regain fertility. Reversal procedures include those used to restore the flow in the FALLOPIAN TUBE or the VAS DEFERENS.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
A territory of northwest Canada, bounded on the north by the Arctic Ocean, on the south by British Columbia, and on the west by Alaska. Its capital is Whitehorse. It takes its name from the Yukon River, the Indian yu-kun-ah, meaning big river. (From Webster's New Geographical Dictionary, 1988, p1367 & Room, Brewer's Dictionary of Names, 1992, p608)
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A class of phenolic acids related to chlorogenic acid, p-coumaric acid, vanillic acid, etc., which are found in plant tissues. It is involved in plant growth regulation.
A resinous substance obtained from beehives that is used traditionally as an antimicrobial. It is a heterogeneous mixture of many substances.
Dioxygenases that catalyze the peroxidation of methylene-interrupted UNSATURATED FATTY ACIDS.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Genes of IAP elements (a family of retrovirus-like genetic elements) which code for virus-like particles (IAPs) found regularly in rodent early embryos. ("Intracisternal" refers to the cisternae of the endoplasmic reticulum.) Under certain circumstances, such as DNA hypomethylation they are transcribed. Their transcripts are found in a variety of neoplasms, including plasmacytomas, neuroblastoma, rhabdomyosarcomas, teratocarcinomas, and colon carcinomas.
Drugs whose drug name is not protected by a trademark. They may be manufactured by several companies.
The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.
The amount that a health care institution or organization pays for its drugs. It is one component of the final price that is charged to the consumer (FEES, PHARMACEUTICAL or PRESCRIPTION FEES).
Directions written for the obtaining and use of DRUGS.
The charge levied on the consumer for drugs or therapy prescribed under written order of a physician or other health professional.
Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.

Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. (1/242)

We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic antioxidant, inhibited the stimulation of prostaglandin (PG) synthesis in cultured human oral epithelial cells and in an animal model of acute inflammation. Treatment of cells with CAPE (2.5 microg/ml) suppressed phorbol ester (12-O-tetradecanoylphorbol-13-acetate; TPA) and calcium ionophore (A23187)-mediated induction of PGE2 synthesis. This relatively low concentration of CAPE did not affect amounts of cyclooxygenase (COX) enzymes. CAPE nonselectively inhibited the activities of baculovirus-expressed hCOX-1 and hCOX-2 enzymes. TPA- and A23187-stimulated release of arachidonic acid from membrane phospholipids was also suppressed by CAPE (4-8 microg/ml). Higher concentrations of CAPE (10-20 microg/ml) suppressed the induction of COX-2 mRNA and protein mediated by TPA. Transient transfections using human COX-2 promoter deletion constructs were performed; the effects of TPA and CAPE were localized to a 124-bp region of the COX-2 promoter. In the rat carrageenan air pouch model of inflammation, CAPE (10-100 mg/kg) caused dose-dependent suppression of PG synthesis. Amounts of COX-2 in the pouch were markedly suppressed by 100 mg/kg CAPE but were unaffected by indomethacin. These data are important for understanding the anticancer and anti-inflammatory properties of CAPE.  (+info)

Tyrosol, the major olive oil biophenol, protects against oxidized-LDL-induced injury in Caco-2 cells. (2/242)

Experimental and clinical evidence suggest that oxidative stress causes cellular damage, leading to functional alterations of the tissue. Free radicals may thus play an important role in the pathogenesis of a number of human diseases. Among pro-oxidant agents, oxidized LDL lead to the production of cytotoxic reactive species, e.g., lipoperoxides, causing tissue injury and various subsequent pathologies including intestinal diseases. Thus, to analyze the oxidative damage induced by oxidized LDL to intestinal mucosa, we evaluated morphological and functional changes induced in the human colon adenocarcinoma cell line, Caco-2. In addition, we examined the protective effects exerted by tyrosol, 2-(4-hydroxyphenyl)ethanol, the major phenolic compound present in olive oil. Caco-2 cell treatment (24 and/or 48 h) with oxidized LDL (0.2 g/L) resulted in cytostatic and cytotoxic effects characterized by a series of morphological and functional alterations: membrane damage, modifications of cytoskeleton network, microtubular disorganization, loss of cell-cell and cell-substrate contacts, cell detachment and cell death. The oxidized LDL-induced alterations in Caco-2 cells were almost completely prevented by tyrosol which was added 2 h before and present during the treatments. Our results suggest that some biophenols, such as those contained in olive oil, may counteract the reactive oxygen metabolite-mediated cellular damage and related diseases, by improving in vivo antioxidant defenses.  (+info)

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex. (3/242)

Colorectal cancer is a major cause of cancer deaths in Western countries, but epidemiological data suggest that dietary modification might reduce these by as much as 90%. Cyclo-oxygenase 2 (COX2), an inducible isoform of prostaglandin H synthase, which mediates prostaglandin synthesis during inflammation, and which is selectively overexpressed in colon tumours, is thought to play an important role in colon carcinogenesis. Curcumin, a constituent of turmeric, possesses potent anti-inflammatory activity and prevents colon cancer in animal models. However, its mechanism of action is not fully understood. We found that in human colon epithelial cells, curcumin inhibits COX2 induction by the colon tumour promoters, tumour necrosis factor alpha or fecapentaene-12. Induction of COX2 by inflammatory cytokines or hypoxia-induced oxidative stress can be mediated by nuclear factor kappa B (NF-kappaB). Since curcumin inhibits NF-kappaB activation, we examined whether its chemopreventive activity is related to modulation of the signalling pathway which regulates the stability of the NF-kappaB-sequestering protein, IkappaB. Recently components of this pathway, NF-kappaB-inducing kinase and IkappaB kinases, IKKalpha and beta, which phosphorylate IkappaB to release NF-kappaB, have been characterised. Curcumin prevents phosphorylation of IkappaB by inhibiting the activity of the IKKs. This property, together with a long history of consumption without adverse health effects, makes curcumin an important candidate for consideration in colon cancer prevention.  (+info)

Olive oil phenolics are dose-dependently absorbed in humans. (4/242)

Olive oil phenolic constituents have been shown, in vitro, to be endowed with potent biological activities including, but not limited to, an antioxidant action. To date, there is no information on the absorption and disposition of such compounds in humans. We report that olive oil phenolics, namely tyrosol and hydroxytyrosol, are dose-dependently absorbed in humans after ingestion and that they are excreted in the urine as glucuronide conjugates. Furthermore, an increase in the dose of phenolics administered increased the proportion of conjugation with glucuronide.  (+info)

Colon cancer chemopreventive drugs modulate integrin-mediated signaling pathways. (5/242)

Epidemiological studies of colorectal cancer incidence suggest that the development of this disease can be modulated by dietary factors. Among the micronutrients showing significant efficacy in tumor prevention are polyphenolic antioxidants found in fruits and vegetables. Epidemiological studies also indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of colorectal cancer. Integrin-mediated cell-matrix contact provides critical signaling that regulates cellular proliferation, migration, and apoptosis. A signaling mediator for this system is focal adhesion kinase (FAK). Thus far, FAK has not been identified as a target for the inhibitory action of any chemopreventive drug in vivo or in vitro. However, the loss of integrin-mediated cell-matrix contact can induce apoptosis (anoikis), and effective chemopreventive agents typically increase the rate of enterocyte apoptosis. Therefore, we asked whether the NSAID, sulindac sulfide, and the phenolic antioxidant, caffeic acid phenethyl ester (CAPE), affected FAK expression or tyrosine phosphorylation in human colon carcinoma cells. We show that subapoptotic doses of both sulindac sulfide and CAPE caused a rearrangement of the actin cytoskeleton and consequently the loss of focal adhesion plaques. These drugs also reduced the tyrosine phosphorylation of FAK and an associated factor, p130Cas. Steady-state levels of these proteins, together with other relevant signaling molecules, remained unchanged after treatments. Finally, we show that both CAPE and sulindac reduced cell invasion, a functional assay for the inhibition of signaling downstream of FAK. These data strongly suggest that chemopreventive drugs can regulate FAK activity. In conclusion, these novel studies add modulation of integrin-mediated signaling to the spectrum of activity of NSAIDs and plant phenolics.  (+info)

Transport mechanism and metabolism of olive oil hydroxytyrosol in Caco-2 cells. (6/242)

3,4-dihydroxyphenylethanol (hydroxytyrosol; DPE) is the major phenolic antioxidant present in extra virgin olive oil, either in a free or esterified form. Despite its relevant biological effects, no data are available on its bioavailability and metabolism. The aim of the present study is to examine the molecular mechanism of DPE intestinal transport, using differentiated Caco-2 cell monolayers as the model system. The kinetic data demonstrate that [(14)C]DPE transport occurs via a passive diffusion mechanism and is bidirectional; the calculated apparent permeability coefficient indicates that the molecule is quantitatively absorbed at the intestinal level. The only labelled DPE metabolite detectable in the culture medium by HPLC (10% conversion) is 3-hydroxy-4-methoxyphenylethanol, the product of catechol-O-methyltransferase; when DPE is assayed in vitro with the purified enzyme a K(m) value of 40 microM has been calculated.  (+info)

Inversion of stereospecificity of vanillyl-alcohol oxidase. (7/242)

Vanillyl-alcohol oxidase (VAO) is the prototype of a newly recognized family of structurally related oxidoreductases sharing a conserved FAD-binding domain. The active site of VAO is formed by a cavity where the enzyme is able to catalyze many reactions with phenolic substrates. Among these reactions is the stereospecific hydroxylation of 4-ethylphenol-forming (R)-1-(4'-hydroxyphenyl)ethanol. During this conversion, Asp-170 is probably critical for the hydration of the initially formed p-quinone methide intermediate. By site-directed mutagenesis, the putative active site base has been relocated to the opposite face of the active site cavity. In this way, a change in stereospecificity has been achieved. Like native VAO, the single mutants T457E, D170A, and D170S preferentially converted 4-ethylphenol to the (R)-enantiomer of 1-(4'-hydroxyphenyl)ethanol. The double mutants D170A/T457E and D170S/T457E exhibited an inverted stereospecificity with 4-ethylphenol. Particularly, D170S/T457E was strongly (S)-selective, with an enantiomeric excess of 80%. The crystal structure of D170S/T457E, in complex with trifluoromethylphenol, showed a highly conserved mode of ligand binding and revealed that the distinctive catalytic properties of this mutant are not caused by major structural changes.  (+info)

Oxidized LDL upregulates angiotensin II type 1 receptor expression in cultured human coronary artery endothelial cells: the potential role of transcription factor NF-kappaB. (8/242)

BACKGROUND: We demonstrated earlier that angiotensin II (Ang II), by AT(1) receptor activation, upregulates oxidized LDL (ox-LDL) endothelial receptor LOX-1 gene expression and uptake of ox-LDL in human coronary artery endothelial cells (HCAECs). In this study, we investigated the regulation of Ang II receptors (AT1R and AT2R) by ox-LDL and the role of the redox-sensitive transcription factor NF-kappaB in this process. METHODS AND RESULTS: HCAECs were incubated with ox-LDL for 24 hours. Ox-LDL (10 to 40 microg protein/mL) upregulated AT1R but not AT2R, mRNA, or protein. Ox-LDL degraded IkappaBalpha in cytoplasm and activated transcription factor NF-kappaB (P65) in HCAEC nuclear extract. Treatment of cells with the antioxidant alpha-tocopherol (10 to 50 micromol/L) attenuated ox-LDL-mediated degradation of IkappaBalpha and activation of NF-kappaB (P65) and inhibited the upregulation of AT1R mRNA and protein. The role of NF-kappaB signal transduction was further examined by use of an NF-kappaB inhibitor, caffeic acid phenethyl ester (CAPE). Pretreatment of cells with CAPE inhibited ox-LDL-mediated degradation of IkappaBalpha and NF-kappaB activation and inhibited ox-LDL-induced upregulation of AT1R expression. Incubation of cells with both ox-LDL and Ang II increased cell injury, measured as cell viability and LDH release, compared with either ox-LDL or Ang II alone. alpha-Tocopherol as well as the specific AT1R blocker CV11974 (candesartan) attenuated the cell-injurious effects of ox-LDL. CONCLUSIONS: These observations suggest an important role of ox-LDL-mediated AT1R upregulation in cell injury. In this process, NF-kappaB activation seems to play a critical role in signal transduction. These findings provide a basis for the use of antioxidants and AT1R blockers in designing therapy of atherosclerosis.  (+info)

Fig. S1. The apoptotic effect of caffeic acid phenethyl ester (CAPE) on human CD4+ T cells. CD4+ T cells (106 cells/ml) were cultured for 48 h in the indicated concentrations of CAPE (0-100 μM). The percentage of annexin-V+ and 7-amino actinomycin D (7-AAD)+ cells were measured by flow cytometry.. Fig. S2. The apoptotic effect of caffeic acid phenethyl ester (CAPE) on stimulated human CD4+ T cells. CD4+ T cells (106 cells/ml) were cultured for 48 h in the absence or presence of CAPE (10 μM) with soluble anti-CD3 and anti-CD28 monoclonal antibodies (2 μg/ml) stimulation. The percentage of annexin-V+ and 7-amino actinomycin D (7-AAD)+ cells from four asthmatic patients were measured by flow cytometry.. Fig. S3. Caffeic acid phenethyl ester (CAPE) inhibits interferon (IFN)-γ and interleukin (IL)-5 production by polarized T helper type 1 (Th1) and Th2 cells. Polarized helper T cells (106 cells/ml) were cultured for 48 h in the absence or presence of CAPE (10 μM) with soluble anti-CD3 and ...
TY - JOUR. T1 - Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. AU - Lin, Hui Ping. AU - Lin, Ching Yu. AU - Huo, Chieh. AU - Hsiao, Ping Hsuan. AU - Su, Liang Cheng. AU - Jiang, Shih Sheng. AU - Chan, Tzu Min. AU - Chang, Chung Ho. AU - Chen, Li Tzong. AU - Kung, Hsing Jien. AU - Wang, Horng Dar. AU - Chuu, Chih Pin. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Prostate cancer (PCa) patients receiving the androgen ablation therapy ultimately develop recurrent castration-resistant prostate cancer (CRPC) within 1-3 years. Treatment with caffeic acid phenethyl ester (CAPE) suppressed cell survival and proliferation via induction of G1 or G2/M cell cycle arrest in LNCaP 104-R1, DU-145, 22Rv1, and C4-2 CRPC cells. CAPE treatment also inhibited soft agar colony formation and retarded nude mice xenograft growth of LNCaP 104-R1 cells. We identified that CAPE treatment significantly reduced ...
TY - JOUR. T1 - Caffeic acid phenethyl ester inhibits nuclear factor-κB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4+ T cells. AU - Wang, L. C.. AU - Chu, K. H.. AU - Liang, Y. C.. AU - Lin, Y. L.. AU - Chiang, B. L.. PY - 2010/5. Y1 - 2010/5. N2 - Summary Caffeic acid phenethyl ester (CAPE), an active component in propolis, is known to have anti-tumour, anti-inflammatory and anti-oxidant properties. In this study, the effects of CAPE on the functions of primary human CD4+ T cells were evaluated in vitro. CAPE significantly suppressed interferon (IFN)-γ and interleukin (IL)-5 production and proliferation of CD4+ T cells stimulated by soluble anti-CD3 and anti-CD28 monoclonal antibodies in both healthy subjects and asthmatic patients. CAPE inhibited nuclear factor (NF)-κB activation and protein kinase B (Akt) phosphorylation, but not p38 mitogen-activated protein kinase (MAPK) phosphorylation in T cells. CAPE also induced active caspase-3 ...
Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells.. Tolba MF1, Esmat A, Al-Abd AM, Azab SS, Khalifa AE, Mosli HA, Abdel-Rahman SZ, Abdel-Naim AB.. Author information. Abstract. Evidence is growing for the beneficial role of selective estrogen receptor modulators (SERM) in prostate diseases. Caffeic acid phenethyl ester (CAPE) is a promising component of propolis that possesses SERM activity. This study aimed at investigating the modulatory impact of CAPE on docetaxel (DOC) and paclitaxel (PTX) cytotoxicity in prostate cancer cells and exploring the possible underlying mechanisms for this chemomodulation. CAPE significantly increased DOC and PTX potency in PC-3, DU-145 and LNCaP prostate cancer cells. Combination index calculations showed synergistic interaction of CAPE/DOC and CAPE/PTX cotreatments in all the tested cell lines. Subsequent mechanistic studies in PC-3 cells indicated that cyclin D1 and c-myc were significantly ...
BACKGROUND:Our aim was to study the effect of caffeic acid phenethyl ester (CAPE) on iNOS and cystathionine gamma-lyase (CSE) of hepatic fibrosis rat, and discuss the anti-hepatic fibrosis mechanism of caffeic acid phenethyl ester. MATERIAL AND METHODS:We observed changes of NO and H2S in serum of hepatic fibrosis rats. Enzyme-linked immunosorbent assay was used to test OD value of iNOS and CSE in serum of each. The expressions of iNOS and CSE protein in the liver were also detected by immunohistochemistry. RESULTS:Compared with the model group, the expression of NO and iNOS was decreased obviously and the level of H2S and CSE was increased in the CAPE group. CONCLUSIONS:CAPE has the effect of anti-hepatic fibrosis, which can be realized through adjusting the expression level of iNOS and CSE.
In vivo and in vitro antıneoplastic actions of caffeic acid phenethyl ester (CAPE): therapeutic perspectives.. Akyol S1, Ozturk G, Ginis Z, Armutcu F, Yigitoglu MR, Akyol O.. Author information. Abstract. Cancer prevention and treatment strategies have attracted increasing interest. Caffeic acid phenethyl ester (CAPE), an active component of propolis extract, specifically inhibits NF-κB at μM concentrations and shows ability to stop 5-lipoxygenase-catalyzed oxygenation of linoleic acid and arachidonic acid. Previous studies have demonstrated that CAPE exhibits antioxidant, antiinflammatory, antiproliferative, cytostatic, antiviral, antibacterial, antifungal, and, most improtantly, antineoplastic properties. The primary goal of the present review is to summarize and critically evaluate the current knowledge regarding the anticancer effect of CAPE in different cancer types.. PMID: 23659443 [PubMed - indexed for MEDLINE]. ...
We found that micromolar concentrations of caffeic acid phenethyl ester blocked voltage-gated sodium channel activity in several invasive cell lines from different cancers, including breast (MDA-MB-231 and MDA-MB-468), colon (SW620) and non-small cell lung cancer (H460). In the MDA-MB-231 cell line, which was adopted as a model, long-term (48h) treatment with 18μM caffeic acid phenethyl ester reduced the peak current density by 91% and shifted steady-state inactivation to more hyperpolarized potentials and slowed recovery from inactivation. The effects of long-term treatment were also dose-dependent, 1μM caffeic acid phenethyl ester reducing current density by only 65%. The effects of caffeic acid phenethyl ester on metastatic cell behaviours were tested on the MDA-MB-231 cell line at a working concentration (1μM) that did not affect proliferative activity. Lateral motility and Matrigel invasion were reduced by up to 14% and 51%, respectively. Co-treatment of caffeic acid phenethyl ester ...
Objective(s): Pulmonary fibrosis (PF) is the most common outcome of a collection of diverse lung disorders known as interstitial lung diseases. It is proposed that alterations in the levels of fibrogenic mediators and the profibrotic/antifibrotic imbalance play a substantial role in the progression of PF in animal models and possibly in humans. Caffeic acid phenethyl ester (CAPE), an active component of propolis, has numerous biological effects. In the present study, the main objective was to investigate the effects of CAPE on some key mediators including TGF-β1, TNF-α and prostaglandin E2 (PGE2 ) involved in profibrotic/antifibrotic balance and pathogenesis of idiopathic pulmonary fibrosis (IPF). Materials and Methods: In this study, forty male Sprague-Dawley rats were divided into 5 groups (n=8). (1)
Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives (honeybee resin), has anti-inflammatory, anti-carcinogenic and anti-bacterial properties. This study was designed to investigate the anti-inflammatory effects of CAPE on Helicobacter pylori-induced NF-kappaB and AP-1 in the gastric epithelial cell line AGS. Electrophoretic mobility shift assay was used to measure NF-kappaB- and AP-1-DNA binding activity. Western blotting was used to detect IkappaB-alpha and COX-2 expression in AGS cells cocultured with H. pylori. The antiproliferative effect of CAPE was measured by MTT assay. Our results showed that caffeic phenethyl ester inhibits H. pylori-induced NF-kappaB and AP-1 DNA-binding activity in a dose (0.1-25 microg ml(-1) approximately 0.35-88 microM) and time- (15-240 min) dependent manner in AGS cells. Maximum inhibition by CAPE was observed at concentrations of 25 microg ml(-1) ( approximately 88 microM) CAPE prevented H. pylori- and cytokine-induced ...
In this Study, it was aimed to investigate the protective effect of caffeic acid phenethyl ester (CAPE) oil cisplatin hepatotoxicity. Thirty New Zealand rabbits were divided into 5 groups as group 1 (saline-injected control, C), group 2 0% ethanol; vehicle for CAPE, E), group 3 (CAPE), group 4 (cisplatin, CS) and group 5 (cisplatin Plus CAPE, CS + CAPE). Cisplatin caused increased immunoreactivity against inducible nitric oxide synthase (iNOS), but CAPE treatment reduced the immunoreactive hepatocytes. Liver malondialdehide (MDA), nitric oxide (NO(center dot)) levels and xanthine oxidase (XO) activities were higher in CS than in groups C and E. Cisplatin treatment also significantly decreased the tissue reduced glutathione (GSH) concentration compared to groups C and E. CAPE administration normalized the tissue GSH level and XO activity in group CS + CAPE, whereas CAPE treatment did not affect MDA level In group CS + CAPE. In addition, CAPE treatment significantly depressed the cisplatin-induced ...
Caffeic acid phenethyl ester (CAPE) is a bioactive component extracted from honeybee hive propolis. Our observations indicated that CAPE treatment suppressed cell proliferation and colony formation of TW2.6 human oral squamous cell carcinoma (OSCC) cells dose-dependently. CAPE treatment decreased G1 phase cell population, increased G2/M phase cell population, and induced apoptosis in TW2.6 cells. Treatment with CAPE decreased protein abundance of Akt, Akt1, Akt2, Akt3, phospho-Akt Ser473, phospho-Akt Thr 308, GSK3β, FOXO1, FOXO3a, phospho-FOXO1 Thr24, phospho-FoxO3a Thr32, NF-κB, phospho-NF-κB Ser536, Rb, phospho-Rb Ser807/811, Skp2, and cyclin D1, but increased cell cycle inhibitor p27Kip. Overexpression of Akt1 or Akt2 in TW2.6 cells rescued growth inhibition caused by CAPE treatment. Co-treating TW2.6 cells with CAPE and 5-fluorouracil, a commonly used chemotherapeutic drug for oral cancers, exhibited additive cell proliferation inhibition. Our study suggested that administration of CAPE is a
Objectives This study aimed to investigate the antioxidant and anti-inflammatory effects of caffeic acid phenethyl ester (CAPE) on the methotrexate (MTX)-induced hepatorenal oxidative damage in rats. ...
CAPE (caffeic acid phenethyl ester) is one of the most valuable and investigated component of propolis which is composed by honeybees. In the current study, we aimed at examining apoptotic effects of CAPE on CCRF-CEM leukemic cells and at determining the roles of mitochondrial membrane potential (MMP) in cell death. ...
Background: To investigate the effects of propofol and caffeic acid phenethyl ester (CAPE) on prevention of lung injury as a remote organ after performing hindlimb ischaemia-reperfusion (IR) in a rat model. ...
Caffeic acid phenethyl ester is Inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities. Cited in 17 publications
Other names: Benzeneethanol; Phenethyl alcohol; «beta»-Hydroxyethylbenzene; «beta»-Phenethyl alcohol; «beta»-Phenylethanol; «beta»-Phenylethyl alcohol; «beta»-PEA; Benzyl Carbinol; Ethanol, 2-phenyl-; Phenethanol; PEA; 2-Phenethyl alcohol; 2-Phenylethanol; 2-Phenylethyl alcohol; Methanol, benzyl-; Phenylethanol; Phenylethyl, beta- alcohol; 2-PEA; «beta»-Fenethylalkohol; «beta»-Fenylethanol; «beta»-Phenethanol; 2-Phenethanol; «beta»-P.E.A.; 1-Phenyl-2-ethanol; Hydroxyethylbenzene; Mellol; Beta-phenylethyl alcohol; Benzenethanol; 1-phenyl-2-ethanol («beta»-phenylethanol); 2-PhenyIethanol; Benzeneethanol (2-Phenylethanol ...
The whey is a by-product obtained during the manufacture of cheese. It includes three types of whey; sweet (SW), acid (AW) and curd (CW). These residues are rich in lactose and proteins. Practically, there are no studies on the use of the three types of whey, as a substrate of micro-organisms for the production of phenylethyl alcohol (PEA). We assessed the production of PEA by Kluyveromyces marxianus using SW, AW and CW as substrate. Whey pH was adjusted to 4.8, pasteurized at 63C/30min and inoculated with K. marxianus (1×106CFUmL?1). The inoculated whey was embedded in agitation (180rpm) at 30C for 96h. The identification and quantification of PEA was performed by gas chromatography. In addition, it was determined the percentage of (???) lactose by molecular structure with nuclear magnetic resonance. K. marxianus was capable of producing PEA in the three types of whey (SW, AW and CV) in maximum concentrations of 0.96, 0.70, and 0.47g L?1, respectively. For SW (maximum concentration of PEA), it ...
An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine.. Caffeic acid phenethyl ester, or CAPE, is a compound isolated from honeybee hive propolis, the resin used by bees to patch up holes in hives. Propolis has been used for centuries as a natural remedy for conditions ranging from sore throats and allergies to burns and cancer. But the compound has not gained acceptance in the clinic due to scientific questions about its effect on cells.. In a paper published in Cancer Prevention Research, researchers combined traditional cancer research methods with cutting-edge proteomics to find that CAPE arrests early-stage prostate cancer by shutting down the tumor cells system for detecting sources of nutrition.. If you feed CAPE to mice daily, their tumors will stop growing. After several weeks, if you stop the treatment, the tumors will begin to grow ...
Myeloid differentiation protein 2 (MD2) is an essential molecule which recognizes lipopolysaccharide (LPS), leading to initiation of inflammation through the activation of Toll-like receptor 4 (TLR4) signaling. Caffeic acid phenethyl ester (CAPE) from propolis of honeybee hives could interfere interactions between LPS and the TLR4/MD2 complex, and thereby has promising anti-inflammatory properties. In this study, we designed and synthesized 48 CAPE derivatives and evaluated their anti-inflammatory activities in mouse primary peritoneal macrophages (MPMs) activated by LPS. The most active compound, 10s, was found to bind with MD2 with high affinity, which prevented formation of the LPS/MD2/TLR4 complex. The binding mode of 10s revealed that the major interactions with MD2 were established via two key hydrogen bonds and hydrophobic interactions. Furthermore, 10s showed remarkable protective effects against LPS-caused ALI (acute lung injury) in vivo. Taken together, this work provides new lead ...
Transthyretin (TTR) is a homotetrameric serum protein associated with amyloidoses such as familial amyloid polyneuropathy and senile systemic amyloidosis. The amyloid fibril formation of TTR can be inhibited through stabilization of the TTR tetramer by the binding of small molecules. In this study, we examined the inhibitory potency of caffeic acid phenethyl ester (CAPE) and its derivatives. Thioflavin T assay showed that CAPE suppressed the amyloid fibril formation of TTR. Comparative analysis of the inhibitory potencies revealed that phenethyl ferulate was the most potent among the CAPE derivatives. The binding of phenethyl ferulate and the selected compounds to TTR were confirmed by the 8-anilino-1-naphthalenesulfonic acid displacement and X-ray crystallography. It was also demonstrated that Bio 30, which is a CAPE-rich commercially available New Zealand propolis, inhibited ...
SOURCE: Guney M, et al. (2007). Protective effect of caffeic acid phenethyl ester (CAPE) on fluoride-induced oxidative stress and apoptosis in rat endometrium. Environ Toxicol Pharmacol. 24(2):86-91.. Fluoride is a strong, hard anion and cumulative toxic agent. The effect of fluoride intoxication on lipid peroxidation in endometrial tissue and the protective effects of combinations of vitamins E and C in rats were studied. Additionally, the apoptotic changes in endometrial tissue were examined. Experimental groups were as follows: control group; a group treated with 100 mg/l fluoride (F group); and a group treated with 100 mg/l fluoride plus vitamins E and C (F+Vit group). The F and F+Vit groups were treated orally with fluoride for 30 days. Vitamins E and C were injected simultaneously at doses of 50 mg/kg day i.m. and 20 mg/kg day body weight i.p. Extensive formation of DNA strand breaks, the typical biochemical feature of apoptosis, was detected with the use of the terminal deoxynucleotidyl ...
To understand the material basis of antitumor activity of Chinese propolis water extract (CPWE), we developed a simple and efficient method using macroporous absorptive resin coupled with preparative high performance liquid chromatography and separated and purified eleven chemical components (caffeic acid, ferulic acid, isoferulic acid, 3,4-dimethoxycinnamic acid, pinobanksin, caffeic acid benzyl ester, caffeic acid phenethyl ester, apigenin, pinocembrin, chrysin, and galangin) from CPWE; then we tested the antitumor activities of these eleven components using different human tumor cell lines (MCF-7, MDA-MB-231, HeLa, and A549). Furthermore, cell migration, procaspase 3 level, and reactive oxygen species (ROS) of effective components from CPWE were investigated. Our data showed that antitumor activities of the eleven components from CPWE were different from each other. CPWE and its effective components induced apoptosis by inhibiting tumor cell migration, activating caspase 3, and promoting ROS
Vascular endothelial growth factor (VEGF) is a key regulator of pathogenic angiogenesis in diseases such as cancer and diabetic retinopathy. Bee products [royal jelly (RJ), bee pollen, and Chinese red propolis] from the honeybee, Apis mellifera, have been used as traditional health foods for centuries. The aim of this study was to investigate the anti-angiogenic effects of bee products using human umbilical vein endothelial cells (HUVECs). In an in vitro tube formation assay, HUVECs and fibroblast cells were incubated for 14 days with VEGF and various concentrations of bee products [RJ, ethanol extract of bee pollen, ethanol extract of Chinese red propolis and its constituent, caffeic acid phenethyl ester (CAPE)]. To clarify the mechanism of in vitro angiogenesis, HUVEC proliferation and migration were induced by VEGF with or without various concentrations of RJ, bee pollen, Chinese red propolis, and CAPE. RJ, bee pollen, Chinese red propolis, and CAPE significantly suppressed VEGF-induced in vitro tube
The triple-negative breast cancer (TNBC) patients have a high mortality due to paucity of effective treatments. We have utilized human MDA-MB-231 (MDA-231) BC cells, often serving as a model of TNBC, to determine whether CAPE (caffeic acid phenethyl ester), a major medicinal component of propolis, can combat TNBC as a preventive, therapeutic, and/or adjuvant to chemotherapeutic drugs. We found that CAPE inhibits MDA-231 cell growth in vitro and in vivo. In vitro: CAPE dose-dependently inhibits MDA-231 cell growth and has a strong effect on gene and protein expression without affecting non-tumorigenic cells. It inhibits cell proliferation and anti-apoptotic genes, decreases oncogenes, inflammatory cytokines, cyclins, and certain receptors and growth factors (i.e., EGFR, IGFR-like 1&2, RAR, Egr-1, and NF-\#954;B1&2 transcription factors). CAPE also increases p21 and p27. Notably, CAPE down-regulates mdr-1 gene, considered responsible for the resistance of cancer cells to chemotherapeutic agents, ...
Cell Culture and Chemicals. SW1116 cells, a cell line derived from human colon adenocarcinoma, were obtained from American Type Culture Collection (Manassas, VA) and cultured in Leibovitzs L-15 medium containing 10% (v/v) heat-inactivated fetal bovine serum, 100 U/ml penicillin, and 100 μg/ml streptomycin. Chemicals were purchased from Sigma-Aldrich (St. Louis, MO) unless otherwise stated. Caffeic acid phenethyl ester (CAPE) was purchased from Calbiochem (San Diego, CA), and celecoxib was a kind gift from SEARLE (Evanston, IL).. Estimation of Cell Viability. Cell viability was assayed by routine 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) reduction method. Briefly, SW1116 cells were seeded into a 96-well plate and incubated for 24 h for attachment. They were then incubated with different drugs for different times at 37°C. At the end of incubation, the medium was aspirated. The remaining cells were further incubated with 0.25 mg/ml MTT for 3 h. MTT was extracted with isopropanol ...
Over recent years, several studies have related olive oil ingestion to a low incidence of several diseases, including breast cancer. Hydroxytyrosol and tyrosol are two of the major phenols present in virgin olive oils. Despite the fact that they have been linked to cancer prevention, there is no evidence that clarifies their effect in human breast tumor and non-tumor cells. In the present work, we present hydroxytyrosol and tyrosols effects in human breast cell lines. Our results show that hydroxytyrosol acts as a more efficient free radical scavenger than tyrosol, but both fail to affect cell proliferation rates, cell cycle profile or cell apoptosis in human mammary epithelial cells (MCF10A) or breast cancer cells (MDA-MB-231 and MCF7). We found that hydroxytyrosol decreases the intracellular reactive oxygen species (ROS) level in MCF10A cells but not in MCF7 or MDA-MB-231 cells while very high amounts of tyrosol is needed to decrease the ROS level in MCF10A cells. Interestingly, hydroxytyrosol
Hydroxytyrosol itself in pure form is a colorless, odorless liquid. The olives, leaves and olive pulp contain large amounts of hydroxytyrosol (compared to olive oil), most of which can be recovered to produce hydroxytyrosol extracts.[1] However, it was found that black olives, such as common canned variety, containing iron(II) gluconate contained little hydroxytyrosol, as iron salts are catalysts for its oxidation.[2]. Hydroxytyrosol is mentioned by the scientific committee of the European Food Safety Authority as one of several olive oil polyphenols under preliminary research for the potential to affect blood lipid levels, although there is no evidence from high-quality clinical research to indicate that this effect exists.[3]. ...
Oxidative stress is involved in several processes including cancer, aging and cardiovascular disease, and has been shown to potentiate the therapeutic effect of drugs such as doxorubicin. Doxorubicin causes significant cardiotoxicity characterized by marked increases in oxidative stress and mitochondrial dysfunction. Herein, we investigate whether doxorubicin-associated chronic cardiac toxicity can be ameliorated with the antioxidant hydroxytyrosol in rats with breast cancer. Thirty-six rats bearing breast tumors induced chemically were divided into 4 groups: control, hydroxytyrosol (0.5 mg/kg, 5 days/week), doxorubicin (1 mg/kg/week), and doxorubicin plus hydroxytyrosol. Cardiac disturbances at the cellular and mitochondrial level, mitochondrial electron transport chain complexes I-IV and apoptosis-inducing factor, and oxidative stress markers have been analyzed. Hydroxytyrosol improved the cardiac disturbances enhanced by doxorubicin by significantly reducing the percentage of altered ...
CAPE is an effective inhibitor of NF-kappaB activation in PC-3 cells, but the mechanism of apoptosis, and the corresponding loss of IAP expression, is caspase-dependent.
An antimicrobial, antiseptic, and disinfectant that is used also as an aromatic essence and preservative in pharmaceutics and perfumery.
0028]Synthetic hydroxytyrosol may be prepared with a purity ,90% is a process comprising the steps of hydrogenating 3,4-dihydroxymandelic acid or a 3,4-dihydroxymandelic acid C1-10-alkyl ester in a C1-10-alkanol in the presence of a precious metal hydrogenation catalyst and optional reduction of the formed (3,4-dihydroxyphenyl)-acetic acid C1-10-alkyl ester is to form 2-(3,4-dihydroxyphenyl)-ethanol (=hydroxytyrosol) a specific example of which is described below. The purity of hydroxytyrosol can be determined by methods known to a person skilled in the art such as e.g. by HPLC, or LC-MS. The hydrogenation may be carried out in the presence of a precious metal catalyst such as Pd and Rh, separately or in mixtures, in a manner known per se. In order to increase the activity and stability of the catalysts they are preferably used on carriers such as activated carbon, alumina or kieselguhr. The preferred hydrogenation catalyst in the present case is Pd/C. The hydrogenation is carried out in the ...
Mediterranean countries have lower rates of mortality from cardiovascular disease and cancer than Northern European or other Western countries. This has been attributed, at least in part, to the so-called Mediterranean diet, which is composed of specific local foods, including olive oil. Traditionally, many beneficial properties associated with this oil have been ascribed to its high oleic acid content. Today, it is clear that many of the beneficial effects of ingesting virgin olive oil are due to its minor compounds. This review summarizes the existing knowledge concerning the chemistry, pharmacokinetics, and toxicology of hydroxytyrosol, a minor compound of virgin olive oil, as well as this compounds importance for health. The main findings in terms of its beneficial effects in cardiovascular disease and cancer, including its properties against inflammation and platelet aggregation, are emphasized. New evidence and strategies regarding the use of hydroxytyrosol as a natural drug for the ...
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TY - JOUR. T1 - Chemoenzymatic synthesis of hydroxytyrosol monoesters and their suppression effect on nitric oxide production stimulated by lipopolysaccharides. AU - Sakakura, Ayaka. AU - Pauze, Martin. AU - Namiki, Atsuhiro. AU - Funakoshi-Tago, Megumi. AU - Tamura, Hiroomi. AU - Hanaya, Kengo. AU - Higashibayashi, Shuhei. AU - Sugai, Takeshi. N1 - Funding Information: M.P. thanks both of Graduate School of SIGMA Clermont and Graduate School of Pharmaceutical Sciences, Keio University, to participate in this study as a visiting research student under agreement from May to September in 2017. This work was supported by Japan society for the Promotion of Science KAKENHI (17K08286) for M.F.-T. and by a grant from a public interest incorporated foundation Amano Institute of Technology for T.S. and are gratefully acknowledged with thanks. Publisher Copyright: © 2018 Japan Society for Bioscience, Biotechnology, and Agrochemistry.. PY - 2019. Y1 - 2019. N2 - Fatty acid monoesters of hydroxytyrosol ...
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To eliminate this confusion, Porter and Sobel used two odors with minimal trigeminal stimulation - essence of rose (phenyl ethyl alcohol) and cloves (eugenol) - as well as two trigeminal odorants (propionic acid, which smells like vinegar, and amyl acetate, which smells like banana). They delivered the odors through a specially designed mask with an artificial septum that provided separate air flow to each nostril. In addition, they conducted similar experiments on five volunteers who had no olfactory nerves and therefore couldnt smell at all, a condition known as anosmia. Normal subjects, 16 in all, were able to tell which nostril was receiving a squirt of scent, but anosmic volunteers could localize only the trigeminal odorants, Sobel said. This shows that humans are able to localize odors through the olfactory nerves alone.. One possible objection is that the experimental set-up, with a mask that provides separate air flow to each nostril, is artificial. How behaviorally relevant is that? ...
Candida albicans is an endogenous opportunistic yeast that does not cause infections in healthy individuals. However, disruption of the balance between microbiome and microorganism, the commensal form becomes pathogenic with clinical manifestation. The aim ofthis study was to determine the effect of oleuropein and hydroxytyrosol and their mechanism of action in C. albicans in vitro. Using the SQM approach for modulation ofergosterol synthesiswe found that oleuropein and hydroxytyrosol in concentrations below the MIC after 18 hours of incubation at 35 °C showed their interference in ergosterol biosynthesis pathway. The testing of the effect of hydroxytrosol and oleuropein on the inhibition of blastospore germination of C. albicans showed that after 3 hours of incubation at 37 °C oleuropein and hydroxytyrosol inhibit the germination even in values below MIC affecting the cellular signal pathways (cAMP-PKA). The testing of inhibition of growth of filaments reveals that oleuropein and ...
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Nominated Substances: Phenethyl alcohol. Nomination Date: 03/22/1996 Nominator: Private Individual Rationale: One of twenty-two substances nominated as naturally occurring chemicals in the diet. Since naturally occurring chemicals in the diet have not been a focus of cancer research, it seems reasonable to investigate some of them further as possible hazards because they often occur at high concentrations in foods. In addition, since regulatory agencies are considering a change in the standard protocol from ad libitum feeding to dietary restriction, it is important to know what impact that change will have on carcinogenicity sensitivity. NTP Principles: not specified Status: No Testing ...
One of the best fragments identified in the previous work was L-tryptophan methyl ester (compound 1), so the researchers naturally tried substituting the methyl group. A phenethyl ester (compound 5c) gave a satisfying 10-fold boost in potency, but this turned out to be the best they could get: shorter or longer linkers were both less active, and modifications around the phenyl ring gave marginal improvements at best. Also, changing the ester to an amide decreased affinity. They were, however, able to improve potency another order of magnitude by acylating the nitrogen (compound 6a ...
4-[2-[3,5-Bis(trifluoromethyl)phenyl]ethyl]-3-ethyl-5-(1H-indol-3-ylmethyl)-1H-imidazol-2-one | C24H21F6N3O | CID 44211803 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Pyrimidine, 2-[2-[4-(hexyloxy)phenyl]ethyl]-5-pentyl- | C23H34N2O | CID 71320809 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
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Richard Troum, DO is a Gastroenterologist at 307 Stone Harbor Blvd, Cape May Court House, NJ 08210. Wellness.com provides reviews, contact information, driving directions and the phone number for Cape Atlantic Gastro Assoc in Cape May Court House, NJ.
Диагностика, дифференциальная диагностика; library could come an Behavioral hydroxytyrosol for winter of T2DM. industry; meal is Publishers to value-add( Apostolidis and Lee, 2010). structure; century company and IR expect clearly important with their host for feeling the way of DM.
Hitching Post (Bourbon Stout) is a American Stout style beer brewed by Cape May Brewing Company in Cape May, NJ. 3.56 average with 4 ratings, reviews and opinions.
Caffeic acid phenethyl ester(CAPE) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. A group of heterocyclic esters of caffeic acid was synthesized using Mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catechol ring of caffeic acid esters in the presence of sodium benenesulfinate and sodium toluensulfinate as nucleophiles. Both heterocycle esters of caffeic acid and their arylsulfonyl derivatives were evaluated for their cytotoxic activity against HeLa, SK-OV-3, and HT-29 cancer cell lines. HeLa cells showed the highest sensitivity to the compounds and heterocyclic esters with no substituent on catechol ring showed better activity compared to their substituted counterparts. QSAR studies reemphasized the importance of molecular shape of the compounds for their cytotoxic activity.
Animal data The teratogenicity of benzyl benzoate has been investigated in Pregnant Wistar rats given commercial flour diets supplemented with 0.04 or 1.0% benzyl benzoate, from day 0 to day 20 of gestation (Morita et al., 1980). These dietary levels correspond to the average daily intake of 26 and 646 mg/kg bw. There were no harmful effects of benzyl benzoate on the foetuses with respect to external, skeletal and visceral anomalies. In addition, benzyl acetate and sodium benzoate were tested for developmental toxicity in teratology studies and only produced adverse effects on the foetus at maternally toxic concentrations. At a dose not maternally toxic, phenylethyl alcohol did not affect litter values in a teratology study. However, there were slight differences from control values in respect of some of the morphological changes observed at this dosage which cannot be discounted entirely. The authors suggested that the relevance of the slight differences from control values observed at the ...
Out of these flavonoids, Epigallocatechin gallate is the most significant active compound.Dried green tea leaves generally contain from 8-12% total polyphenols, caffeine (3.5%), theanine (~4%), lignin (6.5%), organic acids (1.5%), protein (15%), and chlorophyll (0.5%). Green tea contains B-vitamins and ascorbic acid, which are destroyed in the process of making black tea. The essential oil contains more than 300 components including aldehydes, phenylethyl alcohols, phenols, hexenal, linalool, dihydroactinidiolide and p-vinylphenol.Traditional UsesTraditionally, Chinese and Indian medicine used green tea as a stimulant, diuretic (to promote the excretion of urine), astringent (to control bleeding and help heal wounds), and to improve heart health. Other traditional uses of green tea include treating flatulence (gas), regulating body temperature and blood sugar, promoting digestion, and improving mental processes ...
Scope Hydroxytyrosol (HT) is the major phenolic compound in virgin olive oil (VOO) in both free and complex forms (secoiridoids; SEC). Proteomics of cardiovascular tissues such as aorta or heart represents a promising tool to uncover the mechanisms of action of phenolic compounds in healthy animals ...
Hydroxytyrosol (HT) is a natural phenolic antioxidant which has neuroprotective effects in models of Parkinsons disease (PD). Due to issues such as rapid metabolism, HT is unlikely to reach the brain at therapeutic concentrations required for a clinical effect. We have previously developed micellar nanocarriers from Pluronic F68® (P68) and dequalinium (DQA) which have suitable characteristics for brain delivery of antioxidants and iron chelators. The aim of this study was to utilise the P68 + DQA nanocarriers for HT alone, or in combination with the iron chelator deferoxamine (DFO), and assess their physical characteristics and ability to pass the blood-brain barrier and protect against rotenone in a cellular hCMEC/D3-SH-SY5Y co-culture system. Both HT and HT + DFO formulations were less than 170 nm in size and demonstrated high encapsulation efficiencies (up to 97%). P68 + DQA nanoformulation enhanced the mean blood-brain barrier (BBB) passage of HT by 50% (p 0.0001, n = 6). This resulted in ...
NEW YORK (Reuters Health) - A mixture of compounds called phenols, extracted from virgin olive oil, inhibits the process by which colon cells become cancerous, according to lab experiments described in the International Journal of Cancer.. Olive oil is suggested to be responsible in part for the beneficial nature of the Mediterranean diet and our data support this view and provides some possible mechanisms for its action, write Dr. Chris I. R. Gill from the University of Ulster in North Ireland and colleagues.. Because the colon is one of the major cancer sites thought to be protected by olive oil, the team studied the potential anti-cancer effects of virgin olive oil phenols in cultured cell lines widely used as models for colorectal cancer.. Incubation of one cancer cell line with increasing concentrations of olive oil phenols for 24 hours protected the cells from DNA damage, the investigators found.. The effect OF olive oil phenols on another cell line after 48 hours of exposure suggested ...
Health Benefits:- The tyrosol esters are potent antibacterials, anti-inflammatories and antioxidants. They can also keep your blood healthy and relieve pain. In addition to this, provisional studies indicate the tyrosol esters may be able to protect you from mental disorders, prevent bone loss, prevent kidney disease, prevent cancer, prevent diabetes and prevent heart disease. However, further research is required before these provisional health benefits can be confirmed.. RDA:- There is currently no official RDA for the tyrosol esters. However, some sources suggest consuming 9mg of oleocanthal and 300mg of tyrosol each day will allow you to activate their health benefits.. Food Sources:- Olives and olive oil are the only natural food sources of tyrosol esters with a 100ml of olive oil supplying you with 18mg of oleocanthal.. Deficiency Symptoms:- The tyrosol esters are not classed as essential nutrients so have no reported deficiency symptoms associated with their consumption.. Overdose ...
Our scientists have formulated Essent as a blend of several high quality Omega-3 fatty acids in a concentrated form, but as natural triglycerides, with an extra high content (85%) of EPA & DHA; and the fatty acid Omega-9 from extra virgin olive oil. Essent also contains a very significant amount of polyphenols (23 mg) in a special blend of hydroxytyrosol and flavanols. Hydroxytyrosol is derived from olive oil and olive fruit extract, while flavanol is derived from cocoa powder ...
Our scientists have formulated Essent as a blend of several high quality Omega-3 fatty acids in a concentrated form, but as natural triglycerides, with an extra high content (85%) of EPA & DHA; and the fatty acid Omega-9 from extra virgin olive oil. Essent also contains a very significant amount of polyphenols (23 mg) in a special blend of hydroxytyrosol and flavanols. Hydroxytyrosol is derived from olive oil and olive fruit extract, while flavanol is derived from cocoa powder ...
GRAPIPRANT Molecular FormulaC26H29N5O3S Average mass491.605 Da CAS 415903-37-6 UNII-J9F5ZPH7NB, CJ 023423, CJ-023423, Phase II, Arrys Therapeutics, CANCER, PAIN, AskAt Phase II, N-{2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl}-N-[(4-methylphenyl)sulfonyl]urea RQ-00000007, MR10A7 9763 AAT-007 Benzenesulfonamide, N-[[[2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methyl- CJ-023,423 N-[[[2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methylbenzenesulfonamide 1-[2-[4-(2-Ethyl-4,6-dimethylimidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]-3-(4-methylphenyl)sulfonylurea 2-Ethyl-4,6-dimethyl-1-[4-[2-[[[[(4-methylphenyl)sulfonyl]amino]carbonyl]amino]ethyl]phenyl]-1H-imidazo[4,5-c]pyridine AAT 007 CJ 023423 Grapiprant MR 10A7 RQ 00000007 RQ 7 Synonyms and Mappings 415903-37-6 GRAPIPRANT [GREEN BOOK] CJ-023 GRAPIPRANT [INN] GRAPIPRANT [WHO-DD] MR-10A7 AAT-007 MR10A7 RQ-00000007 RQ-7 GRAPIPRANT…
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Tyrosol olive oil antioxidant molecule. 3D rendering. Atoms are represented as spheres with conventional colour coding: hydrogen (white), carbon (black), oxygen (red). - Stock Image F018/3230
Finally, Cape May County will get what it deserves.. After many years of discussion and exploration, Cape May will no longer be the only one of New Jerseys 21 counties without its own or a joint community college. Under the joint community college agreement signed in August by officials from Atlantic Community College (ACC) and Cape May and Atlantic counties, a full-service campus will be built in New Jerseys southernmost county by 2001. However, expanded services and course offerings will be provided at existing facilities in Cape May beginning next semester.. The creation of a joint college committed to meeting the needs of Cape May citizens and employers will substantially increase access to higher education, enabling more residents to pursue postsecondary degree programs, training programs, and continuing education. Not only will these individuals benefit intellectually and financially, but the entire region will be strengthened by the expanded educational, economic, and cultural ...
Next, we carried out the reaction under the optimized conditions for phenylacetic acid 2p but in the absence of any indole (Scheme 4A). This experiment revealed that our catalytic system is able to hydrogenate the carboxylic acid to the corresponding alcohol in moderate yields (14% of 2-phenylethanol 5 and 17% of 2-phenetyl phenylacetate 8 were detected, Scheme 4A). The experiment at shorter reaction times and using phenylacetaldehyde 9 as starting material, afforded 2-phenylethanol 5 in good yields (76%, Scheme 4B).. At this point it was interesting to compare the reactivity of several possible alkylating agents, all of them being related derivatives of phenylacetic acid 2p. Thus, reactions of indole 1a were performed in the presence of the [Co(acac)3/Triphos (L1)/Al(OTf)3] system at 140 °C and 30 bar of H2, using phenylacetic acid 2p, phenylacetaldehyde 9, phenethyl alcohol 5 and methyl phenylacetate 6 (usually formed from phenylacetic acid and methanol coming from MCPE cleavage) (Scheme ...
Here we address this problem by using molecular mechanics simulations to build up a detailed picture of the conformational behavior of 2-amino-1-phenylethanol, a noradrenaline analogue, in aqueous solution in both its neutral and protonated forms. For the sake of comparison, equivalent simulations are also performed on the gas-phase molecules and gas-phase hydrated clusters. These calculations reveal the important role that water has to play in determining the conformational preferences and dynamic behavior of the molecules. Water molecules are found to bridge between the various functional groups within the molecule, significantly affecting their relative stabilities in comparison to the gas-phase values. The reorganization of these solvation structures also provides a mechanism for conformational interconversion. The role of the solvent in mediating interactions between the various functional groups within the molecule suggests that in noradrenaline the catechol groups will be able to ...
Olive leaf extract has been found useful in improving resistance to microbial infection. It contains significant qualities of phenolic compounds, such as oleuropein, oleuropeoside, and hydroxytyrosol, that have been shown to have anti microbial properties
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Sitting or standing for long periods of time can lead to a little more than discomfort. When youre in the same position for long periods, your blood doesnt flow as efficiently as it would with regular movement, this causes the veins to work harder to pump your blood up to your heart. The added effort can lead to the veins becoming swollen and varicose.. Whether youre currently trying to hide protruding veins or find yourself falling into a few of the risk categories above, give Dr. Jeffrey Gosin at Shore Vascular & Vein Center a call at (609) 927-VEIN (8346) for more information, get diagnosed or receive treatments. Dont let the rest of summer pass you by, get out there and show off those legs.. Serving: Cape May County: Cape May, Villas, Marmora, Avalon, Wildwood, Ocean City, West Cape May, North Cape May, Wildwood Crest, Upper Township, Middle Township, Lower Township, Woodbine, Dennis Township; Atlantic County: Somers Point, Northfield, Linwood, Egg Harbor Township, Mays Landing, ...
Hail to the Chiefs!2018-02-13T09:30:00. Hail to the Chiefs! An exhibit that highlights more than 15 of our nations leaders, including Washington and Lincoln. On display are artifacts from the Museums collection as well as from a private collector. The exhibit featuresx original documents, books, artwork and artifacts.. Museum of Cape May County504 Route 9 NorthCape May Court HouseNJ08210 ...
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Odour threshold Values for Ketones containing compounds. Access for free or you can order top quality OTVs, EROM measured to standard EN13725
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Product Name:Olive leafextractLatinName:Canarium album Raeusch.Part of Used: leafActive ingredients: Oleuropein , HydroxytyrosolAppearance: Light Brown yellow to brown-yellow fine powderSpecification: Oleuropein 10%~90% , Hydroxytyrosol 5%~98%
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H.A. Joint Formula combines Hydroxytyrosol (Hidrox), a highly potent and protective polyphenol found in olives, with the power of Hyaluronic Acid.
H.A. Joint Formula combines Hydroxytyrosol (Hidrox), a highly potent and protective polyphenol found in olives, with the power of Hyaluronic Acid.
H.A. Joint Formula combines Hydroxytyrosol (Hidrox), a highly potent and protective polyphenol found in olives, with the power of Hyaluronic Acid.
H.A. Joint Formula combines Hydroxytyrosol (Hidrox), a highly potent and protective polyphenol found in olives, with the power of Hyaluronic Acid.
H.A. Joint Formula represents yet another advance in natural joint support. By combining the shock absorbing properties of H.A. with HIDROX (Hydroxytyrosol), a highly potent and protective polyphenol found in olives, Puritys H.A. Joint Formula is truly revolutionary.. CUTTING EDGE INGREDIENTS. HYALURONIC ACID FROM BIOCELL COLLAGEN. Puritys H.A. Joint Formula provides cutting edge support for joint flexibility and mobility and features BioCell Collagen II, which is carefully manufactured through a patented process. This process contain high concentrations of hydrolyzed collagen type II protein and low molecular weight GAGs (glycosaminoglycans), such as Chondroitin Sulfate, Hyaluronic Acid and other proteoglycans that readily absorb through the gastrointestinal tract to allow superior bioavailabilty.. With this greater absorption rate, the H.A. nourishes and revitalizes your joints and tissues. Whats more, H.A. also helps support healthy enzymatic behavior as it relates to joint health, ...
H.A. Joint Formula represents yet another advance in natural joint support. By combining the shock absorbing properties of H.A. with HIDROX (Hydroxytyrosol), a highly potent and protective polyphenol found in olives, Puritys H.A. Joint Formula is truly revolutionary.. CUTTING EDGE INGREDIENTS. HYALURONIC ACID FROM BIOCELL COLLAGEN. Puritys H.A. Joint Formula provides cutting edge support for joint flexibility and mobility and features BioCell Collagen II, which is carefully manufactured through a patented process. This process contain high concentrations of hydrolyzed collagen type II protein and low molecular weight GAGs (glycosaminoglycans), such as Chondroitin Sulfate, Hyaluronic Acid and other proteoglycans that readily absorb through the gastrointestinal tract to allow superior bioavailabilty.. With this greater absorption rate, the H.A. nourishes and revitalizes your joints and tissues. Whats more, H.A. also helps support healthy enzymatic behavior as it relates to joint health, ...
Boc Sciences offers cas 20125-39-7 N6-(2-Phenylethyl)-adenosine in bulk,please inquire us to get a quote for 20125-39-7 N6-(2-Phenylethyl)-adenosine.
N-[2-(3,4-dihydroxyphenyl)ethyl]octadecanamide 105955-10-0 NMR spectrum, N-[2-(3,4-dihydroxyphenyl)ethyl]octadecanamide H-NMR spectral analysis, N-[2-(3,4-dihydroxyphenyl)ethyl]octadecanamide C-NMR spectral analysis ect.
(4-chlorophenyl)-(3,4-dihydroxyphenyl)methanone 134612-84-3 NMR spectrum, (4-chlorophenyl)-(3,4-dihydroxyphenyl)methanone H-NMR spectral analysis, (4-chlorophenyl)-(3,4-dihydroxyphenyl)methanone C-NMR spectral analysis ect.
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The Golm Metabolome Database (GMD) facilitates the search for and dissemination of mass spectra from biologically active metabolites quantified using GC-MS.
Boiling point: 57-59°/2mm. Flash point: 84°(184°F). Density: 1.295. Refractive Index: 1.4610. Store: Room temperature. Free Shipping within the Continental USA. ...
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Phenylethyl alcohol agar selects for Staphylococcus species while inhibiting Gram-negative bacilli (e.g., Escherichia coli, ...
The classical method of diagnosis is to culture aliquots of haemolymph in phenylethyl alcohol broth. Cultures containing A. ...
Lastly, colonies of C. pallescens grown on Phenylethyl Alcohol Agar (PEA) appear woolly at the centre. The conidiophores of C. ...
... phenylethyl alcohol and gamma-butyrolactone, secondary products of alcoholic fermentation". Comptes Rendus de l'Académie des ... Tryptophol is an aromatic alcohol that induces sleep in humans. It is found in wine as a secondary product of ethanol ... This latter compound is transformed to tryptophol by alcohol dehydrogenase. It is formed from tryptophan, along with indole-3- ... Article in French) Lingappa, BT; Prasad, M; Lingappa, Y; Hunt, DF; Biemann, K (1969). "Phenethyl alcohol and tryptophol: ...
... phenylethyl alcohol and gamma-butyrolactone, secondary products of alcoholic fermentation". Comptes Rendus de l'Académie des ... "The Alcohol Content of Bread". Canadian Medical Association Journal. 16 (11): 1394-5. November 1926. PMC 1709087. PMID 20316063 ... The overall chemical formula for alcoholic fermentation is: C6H12O6 → 2 C2H5OH + 2 CO2 Sucrose is a sugar composed of a glucose ... "Yeast alcohol dehydrogenase structure and catalysis". Biochemistry. 53: 5791-803. doi:10.1021/bi5006442. PMC 4165444. PMID ...
... phenylethyl alcohol and gamma-butyrolactone, secondary products of alcoholic fermentation". Comptes Rendus de l'Académie des ... "Classification of Alcohol Use Disorders". Alcohol Research & Health : The Journal of the National Institute on Alcohol Abuse ... Alcoholism, also known as "alcohol use disorder", is a broad term for any drinking of alcohol that results in problems. It was ... Alcohol and Heart Health American Heart Association "Alcohol Facts and Statistics". Retrieved 9 May 2015. "Drink binges 'cause ...
... , also known as phenethyl propanoate or phenylethyl propionate, is the ester of phenethyl alcohol and ...
Usually, phenylethyl alcohol is responsible for the typical odour of rose water but is not always present in rose water ... geraniol and phenyl ethyl alcohol, and also henicosane, 9-nonadecen, eicosane, linalool, citronellyl acetate, methyleugenol, ... In accordance with the ban on alcohol consumption in Islamic countries, rose water is used instead of champagne on the podium ...
The first synthesis of hordenine is due to Barger: 2-phenylethyl alcohol was first converted to 2-phenylethyl chloride using ... This synthesis began with p-methoxy-phenylethyl alcohol, which was simultaneously O-demethylated and converted to the iodide by ... 1999). "Isolation from Beer and Structural Determination of a Potent Stimulant of Gastric Release". Alcohol & Alcoholism. 34: ... heating with HI; the resulting p-hydroxy-phenylethyl iodide was then heated with dimethylamine to give hordenine. Radio- ...
The chief constituent of kewda oil is methyl ether of beta-phenylethyl alcohol(60-80%) which gives the characteristic aroma of ...
The routine included inhaling the odor of rose, lemon, clove, and eucalyptus (phenyl ethyl alcohol, citronellal, eucalyptol, ...
Flowers distilled oil contains phenylethyl alcohol (27%), benzyl alcohol (12%), eicosane (5.6%), eugenol (5.6%), n-tetracosane ... Flowers alcohol extract contains cytotoxic steroids. Ingestion of C. nocturnum has not been well documented, but there is some ...
Of the many components of eleoptene with a pink odor are citronellol, geraniol, nerol, phenylethyl alcohol, but the typical ... The most common chemical compounds present in rose oil are: citronellol, geraniol, nerol, linalool, phenyl ethyl alcohol, ... benzyl alcohol, rhodinyl acetate and phenyl ethyl formate. The key flavor compounds that contribute to the distinctive scent of ... The alcohol is low-pressure evaporated, leaving behind the finished absolute. The absolute may be further processed to remove ...
... its constituents such as phenyl ethyl alcohol, geraniol etc will be listed. This is the most well known technique for ...
... benzyl alcohol, isovaleronitrile, benzyl benzoate, phenylethyl alcohol, isovaleraldehyde, and phenylacetaldoxime. Usually one ...
"Phenylethyl alcohol_msds". Fahlbusch, Karl-Georg; Hammerschmidt, Franz-Josef; Panten, Johannes; Pickenhagen, Wilhelm; ... Hydrogenation of styrene oxide also affords phenethyl alcohol. Phenethyl alcohol can also be prepared by the reaction between ... Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group (C6H5CH2CH2) attached to OH. ... Phenethyl alcohol is prepared commercially via two routes. Most common is the Friedel-Crafts reaction between benzene and ...
... phenylethyl alcohol and gamma-butyrolactone, secondary products of alcoholic fermentation". Comptes rendus hebdomadaires des ... Lingappa, BT; Prasad, M; Lingappa, Y; Hunt, DF; Biemann, K (1969). "Phenethyl alcohol and tryptophol: Autoantibiotics produced ...
... phenylethyl alcohol and gamma-butyrolactone, secondary products of alcoholic fermentation»] Comptes Rendus Hebdomadaires Des ... Ingelesez) «Alcohol Facts and Statistics , National Institute on Alcohol Abuse and Alcoholism (NIAAA)» www.niaaa.nih.gov Noiz ... Ingelesez) «Publications , National Institute on Alcohol Abuse and Alcoholism , Alcohol Use Disorder: A Comparison Between DSM ... Ingelesez) «Beer , alcoholic beverage» Encyclopedia Britannica Noiz kontsultatua: 2018-04-03. *↑ «When Was Beer Invented?» Live ...
The early step in this reaction is the conversion of the primary alcohol to the aldehyde. Addition of the amine is facilitated ... Lisa Kanupp Thalén, Christine Rösch, Jan-Erling Bäckvall (2012). "Synthesis of (R)-2-Methoxy-N-(1-Phenylethyl)Acetamide via ...
Alcohol 13 was formed after SEM protection (SEMCl,i-Pr2NEt) and TIPS removal (HF). In the second part of the sequence alcohol ... The phenylethyl substituent was removed using ClCO2CHClCH3 and the enone group was introduced in a Grieco elimination using ... both alcohol protecting groups removed (NaOMe / meOH) and the allyl alcohol group protected again (TIPS). This allowed removal ... The alcohol was oxidized to the aldehyde using a Parikh-Doering oxidation and TIPS group removal gave hemiacetal 19 called (+)- ...
A related alkaloid sedamine, with only one 2-phenylethyl group on the piperidine ring and found in plants of genus sedum, is ... Farook JM, Lewis B, Gaddis JG, Littleton JM, Barron S (June 2009). "Lobeline, a nicotinic partial agonist attenuates alcohol ... Drug and Alcohol Dependence. 89 (2-3): 282-91. doi:10.1016/j.drugalcdep.2007.02.003. PMID 17368966. Ma Y, Wink M (September ... or alcohol; however, there is limited clinical evidence of any efficacy. Ingestion of lobeline may cause nausea, vomiting, ...
1,3-Dienes were found to be formed upon the treatment of an allylic alcohol with an aryl sulfide in the presence of ... 2-phenylethyl)dimethylamine oxides". J. Am. Chem. Soc. 105 3714-. Kahn, S.D; Erickson, J.A. (1994). "Theoretical Studies of ... To form the xanthate ester, an alcohol reacts with carbon disulfide in the presence of a base, resulting in a metal xanthate ... First, the alcohol displaces the triethylamine on the Burgess reagent, forming the sulfamate ester intermediate. β-hydrogen ...
One of the main reasons for these differential effects is the obviously increased polarity of the hydroxy-substituted phenyl ethyl ... This intermediate was then hydrolyzed with HCl/alcohol to the p-hydroxy-aminoketone, and the product then reduced catalytically ... an alcoholic hydroxy- group, and an N-methylated amino-group. Alternatively, synephrine might be described as a ...
In terms of molecular structure, synephrine has a phenethylamine skeleton, with a phenolic hydroxy- group, an alcoholic hydroxy ... One of the main reasons for these differential effects is the obviously increased polarity of the hydroxy-substituted phenyl ethyl ... This intermediate was then hydrolyzed with HCl/alcohol to the p-hydroxy-aminoketone, and the product then reduced catalytically ...
Later it was found that morphine was more addictive than either alcohol or opium, and its extensive use during the American ... Replacement of the N-methyl group of morphine with an N-phenylethyl group results in a product that is 18 times more powerful ... Morphine withdrawal is considered less dangerous than alcohol, barbiturate, or benzodiazepine withdrawal. The psychological ... alcohol, or sedative-hypnotics, is not fatal by itself in otherwise healthy people. Acute morphine withdrawal, along with that ...
In 2018, American rapper Mac Miller died from an accidental overdose of fentanyl, cocaine and alcohol. On December 16, 2018, ... Synthesis and pharmacology of the diastereoisomers of N-(3-methyl-1-(2-phenylethyl)-4-piperidyl)-N-phenylpropanamide and N-(3- ... Suzuki J, El-Haddad S (February 2017). "A review: Fentanyl and non-pharmaceutical fentanyls". Drug and Alcohol Dependence. 171 ... alcohol, and inhaled anesthetics Hyperventilation Decreased CO2 levels in the serum Respiratory acidosis Decreased fentanyl ...
1-phenylethyl}amino)butanoate. It has a molecular formula of C32H29F5N3O5Na and a molecular weight of 653.58 g/mol. The free ... polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, and a distinct color additive (carmine high tint in the 150 mg ... Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a potent ...
... has been studied for its effects on multiple other conditions, including: Non-alcoholic fatty liver disease Premature ... because two methyl substituents on metformin impart lesser lipophilicity than the larger phenylethyl side chain in phenformin. ... on liver enzymes and body composition in non-diabetic patients with non-alcoholic fatty liver disease and/or non-alcoholic ... excessive alcohol intake, hepatic impairment, concomitant use of certain drugs (e.g. carbonic anhydrase inhibitors such as ...
BKCa-specific: Ethanol (alcohol). *GAL-021. Activators. *BKCa-specific: Flufenamic acid ... phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide. Identifiers CAS Number. *25046-79-1 Y ...
Agonists: Alcohols (e.g., butanol, ethanol (alcohol), trichloroethanol). *m-CPBG. *Phenylbiguanide. *Piperazines (e.g., BZP, ... α-phenyl-1-(2-phenylethyl)-4-piperidine methanol. CAS Number. *132553-86-7 ...
1-methyl-2-phenylethyl]hexanamide. The condensation reaction occurs with loss of water: (S)-PhCH 2CH(CH 3)NH 2 + (S)-HOOCCH(NH ... cigarette smoking and alcohol use disorders. ... Recent studies have demonstrated that stimulants, along with the non- ...
2-Phenethyl alcohol; 2-Phenylethanol; 2-Phenylethyl alcohol; Methanol, benzyl-; Phenylethanol; Phenylethyl, beta- alcohol; 2- ... Phenethyl alcohol; «beta»-Phenylethanol; «beta»-Phenylethyl alcohol; «beta»-PEA; Benzyl Carbinol; Ethanol, 2-phenyl-; ... Beta-phenylethyl alcohol; Benzenethanol; 1-phenyl-2-ethanol («beta»-phenylethanol); 2-PhenyIethanol; Benzeneethanol (2- ... Other names: Benzeneethanol; Phenethyl alcohol; «beta»-Hydroxyethylbenzene; «beta»- ...
2-Phenethyl alcohol; 2-Phenylethanol; 2-Phenylethyl alcohol; Methanol, benzyl-; Phenylethanol; Phenylethyl, beta- alcohol; 2- ... Phenethyl alcohol; «beta»-Phenylethanol; «beta»-Phenylethyl alcohol; «beta»-PEA; Benzyl Carbinol; Ethanol, 2-phenyl-; ... Benzyl, (±)-1-Phenylethyl and 2-Phenylethyl Alcohols and the Corresponding Esters of Benzoic Acid and Its 2-, 3- and 4-Chloro, ... Beta-phenylethyl alcohol; Benzenethanol; 1-phenyl-2-ethanol («beta»-phenylethanol); 2-PhenyIethanol; Benzeneethanol (2- ...
Phenylethyl alcohol. Accession Number. DB02192 (EXPT02549) Type. Small Molecule. Groups. Experimental. Description. An ... Phenethyl_alcohol. PDB Entries. 1eyw / 1hzy / 1i0b / 1i0d / 1jgm / 2i0t / 3x3x / 6agr / 6ahh. Clinical Trials. Clinical Trials ... Monocyclic benzene moiety / Organic oxygen compound / Hydrocarbon derivative / Primary alcohol / Organooxygen compound / ... Alcohol / Aromatic homomonocyclic compound. Molecular Framework. Aromatic homomonocyclic compounds. External Descriptors. ...
... Gómez Aldapa, Carlos ... Evaluation of Waste of the Cheese Industry for the Production of Aroma of Roses (Phenylethyl Alcohol). Waste and Biomass ... as a substrate of micro-organisms for the production of phenylethyl alcohol (PEA). We assessed the production of PEA by ...
... provide p-Amino Phenylethyl Alcohol product and the products related with China p-Amino Phenylethyl Alcohol - cidic ... China p-Amino Phenylethyl Alcohol Suppliers and China p-Amino Phenylethyl Alcohol Manufacturers, ... China p-Amino Phenylethyl Alcohol Suppliers, China p-Amino Phenylethyl Alcohol Manufacturers. ... Send your inquiry to p-Amino Phenylethyl Alcohol supplier. Enter your inquiry here and then click Send. Enter between 20 to ...
PEA (phenylethyl alcohol). Medium-smelling, sweet, honeyed, rough, powdery, rosy, dry petal-like, floral, fruity, grape-like ... we are manufacturing of phenyl ethyl alcohol per month 200 M.T, we also want to market with you , pl give us reply, ... acacia alcohol aldehyde aldehyde c12 aldehyde c14 ambergris amyl cinnamal aurantiol base benzaldehyde castoreum chypre cinnamic ... good morning sir, what about our other products like styrallyl alcohol also we are manufacturing 50 mt per month,and also ...
Phenylethyl alcohol [USP] - Similar structures search, synonyms, formulas, resource links, and other chemical information. ... Substance Name: Phenylethyl alcohol [USP]. RN: 60-12-8. UNII: ML9LGA7468. InChIKey: WRMNZCZEMHIOCP-UHFFFAOYSA-N. Note. *. An ...
Phenylethyl Alcohol, Reagent Phenylethyl Alcohol, Reagent is a widely naturally occurring aromatic alcohol that is found in a ...
... such as benzyl alcohol, phenyl ethyl alcohol; boric acid; 2,4,4′-trichloro-2-hydroxy-diphenyl ether; phenolic compounds, such ... A solution of 2.5% (wt) garlic and a solution of 2.5% (wt) onion were both made using 39C alcohol as the solvent. Briefly, 0.4 ... Method, compositions and compounds, useful in room fresheners employing cyclohexyl alcohol and ester derivatives. ...
PHENETHYL ALCOHOL. ICSC. : 0936. 2-Phenylethane-1-ol. Benzeneethanol. Phenylethyl alcohol. 2-Phenylethanol. April 2013. ...
... v/v phenylethyl alcohol in propylene glycol; Experiment 3: 0, 0.2, 0.4, 0.5, 0.6, 0.8, and 1% v/v phenylethyl alcohol in ... v/v phenylethyl alcohol (Experiment 2), 0.5% v/v phenylethyl alcohol (Experiment 3), or 0.5% m/v vanillin (Experiment 4) in ... 1C) or 3 and 2% v/v phenylethyl alcohol (t23 = −0.93, P = 0.36; Fig. 1E). There was no significant change in heading-judgment ... Smelling 4% v/v phenylethyl alcohol in the left nostril and 1% v/v in the right nostril, as opposed to the other way around, ...
Phenylethyl Alcohol Agar (PEA) S2 Media. Also known as Phenylethanol Agar A selective media utilized for the isolation of ...
Phenylethyl Alcohol. Anti-Infective Agents, Local. Anti-Infective Agents. Central Nervous System Depressants. Physiological ... Drug: LY2216684 Drug: LY2216684 Placebo Drug: Alcohol Placebo containing beverage Drug: Alcohol containing beverage Phase 1 ... Subjects with known or suspected alcohol dehydrogenase deficiency. *Subjects who do not drink alcohol and/or are not willing to ... Have an average weekly alcohol intake that exceeds 14 units per week, or are unwilling to stop alcohol consumption 48 hours ...
Phenylethyl Alcohol. Bronchodilator Agents. Autonomic Agents. Peripheral Nervous System Agents. Physiological Effects of Drugs ... Have an average weekly alcohol intake that exceeds 14 units per week, or are unwilling to stop alcohol consumption for 48 hours ...
benzalkonium chloride, dextrose, microcrystalline cellulose, phenylethyl alcohol, polysorbate 80, purified water, sodium ...
Phenyetbyl alcohol; Phenylethyl butyrate; Phenylethyl phenylacetate; Pimento oil; Pinene, alpha; Para-tert. butyl-cyclohexyl ... Alcohol ingestion stimulates mosquito attraction. J Am Mosq Control Assoc 18: 91-6. ... Anisic alcohol; Anisic aldehyde; Applinal (Q); Bay oil; Benzyl acetate; Benzyl benzoate; Benzyl cinnamate; Benzyl propionate; ... Cinnamic alcohol; cinnamic aldehyde; Cinnamon Leaf Oil: Cinnamyl acetate; cis-3-Hexenol; Citral; Citronella oil; Citronellal; ...
Inactive Ingredients: Water, Alcohol SDA 40B, Squalane, Coenochloris Signiensis Extract (and) Maltodextrin (and) Lecithin, ... Cetyl Alcohol, Olus Oil/Vegetable Oil, Tocopheryl Acetate, Glycine Soja/Glycine Soja, (Soybean) Sterols, Sodium Carboxymethyl ...
"Phenylethyl alcohol_msds". Fahlbusch, Karl-Georg; Hammerschmidt, Franz-Josef; Panten, Johannes; Pickenhagen, Wilhelm; ... Hydrogenation of styrene oxide also affords phenethyl alcohol. Phenethyl alcohol can also be prepared by the reaction between ... Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group (C6H5CH2CH2) attached to OH. ... Phenethyl alcohol is prepared commercially via two routes. Most common is the Friedel-Crafts reaction between benzene and ...
Phenyl Ethyl Alcohol. CAS# 60-12-8. EINECS # 200-456-2. *Chinese/Japanese Origin ... Synthetic AromaChemicals We provide a wide range of synthetic aroma chemicals such as geranylacetone, phenyl ethyl methyl ether ...
... phenylethyl acetate, phenylethyl alcohol, phenylethyl alcohol, phenylethyl isovalerate, piperonal, propionaldehyde, propyl ... the group comprising araliphatic alcohols such as for example: benzyl alcohol; 1-phenylethyl alcohol; 2-phenylethyl alcohol; 3- ... 2-phenylethyl acetate; 2-phenylethyl propionate; 2-phenylethyl isobutyrate; 2-phenylethyl isovalerate; 1-phenylethylacetate; ... 2-phenylethyl methyl ether; 2-phenyl ethyl isoamyl ether; 2-phenyl ethyl-1-ethoxyethyl ether; phenylacetaldehyde dimethylacetal ...
... phenylethyl alcohol; PEA); menthol; and banana (isoamyl acetate; 1% v/v dissolved in 1,2-propanediol). Patients received four ...
Brazil Phenyl Ethyl Alcohol Monthly Import Data Monitoring * Report. * * Region: Brazil €2910EUR$3,300USD£2,612GBP ...
5. s-Phenylethyl Alcohol. 2. 1-n-Propoxy-2-propanol. 6. N-(2-Aminoethyl). ethanolamine ...
2-Phenylethyl alcohol 4. 98. 0.35. -. -. 1 Sigma-Aldrich (St. Louis, MO, USA); 2 obtained by oxidation of 3-hydroxy-2-butanone ...
Phenylethyl Alcohol Blood Agar (PEA) is an enriched selective medium used for the inhibition of facultative gram-negative rods ... Brucella Blood Agar, Phenylethyl Alcohol Blood Agar, Laked Brucella Blood Agar w/ Kanamycin and Vancomycin, Bacteroides Bile ... Brucella Blood Agar, Phenylethyl Alcohol Blood Agar, Laked Brucella Blood Agar w/ Kanamycin and Vancomycin, Bacteroides Bile ... The selective agent, phenylethyl alcohol, reversibly inhibits DNA synthesis and thus inhibits facultative anaerobic gram- ...
Phenylethyl Alcohol / analogs & derivatives* * Phenylethyl Alcohol / pharmacology * Rats * Rats, Wistar * Superoxide Dismutase ...
Phenylethyl Alcohol / analogs & derivatives* * Phenylethyl Alcohol / pharmacology* * Prostatic Neoplasms / pathology* * Tumor ...
Phenylethyl Alcohol. LRAC1472. PHR1723-400MG. Desipramine Hydrochloride. LRAC1473. PHR1829-500MG. Hypromellose. LRAC0715. ... Alcohol. LRAA1629/LRAB6749. Update USP Traceability Statement. 14 November 2018. PHR1970-100MG. Acetaminophen Impurity C. ...
Phenylethyl Alcohol. 3. - View Price 84. Phenylethyl resorcinol. 1. View Price - 85. Phenylmercuric Nitrate. 2. - View Price ...
  • Benzyl alcohol, .alpha. (environmentalchemistry.com)
  • Benzyl alcohol is an aromatic alcohol with the formula C6H5CH2OH. (steunmijnclub.nl)
  • The benzyl group is often abbreviated 'Bn' (not to be confused with 'Bz' which is used for benzoyl), thus benzyl alcohol is denoted as BnOH. (steunmijnclub.nl)
  • Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. (steunmijnclub.nl)
  • Benzyl alcohol C7H8O C6H5CH2OH Phenylcarbinol Phenylmethanol CAS 100-51-6, China Benzyl alcohol CAS 100-51-6 Phemethylol Benzal alcohol C7H8O C6H5CH2OH Manufacturer. (steunmijnclub.nl)
  • Benzyl Alcohol, 100-51-6, C7h8o, Benzyl Chloride, 100-44-7, C7h7cl, Melamine, C6h5CH2oh Company Introduction Luxi Chemical Group is a state-owned company with 1billion USD assets and 12000 employees, I am seeking opportunities to do business with you on benzyl chloride and benzyl alcohol. (steunmijnclub.nl)
  • Aug 19, 2018· Benzyl Alcohol BP USP NF ACS Reagent Grade Supplier, Manufacturer's Representative. (steunmijnclub.nl)
  • Benzyl Alcohol, CAS No. 100-51-6 is an aromatic primary alcohol with the molecular formula C7H8O. (steunmijnclub.nl)
  • Benzyl Alcohol is soluble in water and readily soluble in alcohol and ether. (steunmijnclub.nl)
  • Benzyl alcohol readily forms esters with various a more. (steunmijnclub.nl)
  • Benzyl Alcohol - You find here 19 suppliers from Germany Austria and Poland. (steunmijnclub.nl)
  • henylcarbinol is also known as benzyl alcohol. (steunmijnclub.nl)
  • Benzyl Alcohol contains not less than 98.0 percent and not more than 100.5 percent of C7H8O. (steunmijnclub.nl)
  • Labeling- Where Benzyl Alcohol is intended for use in the manufacture of injectable dosage forms, it is so labeled. (steunmijnclub.nl)
  • Clarity of solution- Test solution- Dissolve 2.0 g of Benzyl Alcohol in 60 mL of water, and mix. (steunmijnclub.nl)
  • Find Benzyl Alcohol manufacturers, Benzyl Alcohol suppliers, exporters, wholesalers and distributors in Gujarat India - List of Benzyl Alcohol selling companies from Gujarat with catalogs, phone numbers, addresses & prices for Benzyl Alcohol. (steunmijnclub.nl)
  • Compare and research Benzyl Alcohol companies and businesses online Richman Chemical Inc Richman Chemical, Inc. (RCI) provides project management, custom/contract manufacturing and sourcing services to the chemical and life sciences industries including start-up companies. (steunmijnclub.nl)
  • Benzyl alcohol USP [100-51-6]. (steunmijnclub.nl)
  • Benzyl Alcohol ACS Analytical Reagent Benzenemethanol C6H5CH2OH Formula Wt 108.14 CAS Number 100-51-6. (steunmijnclub.nl)
  • For details please visit Benzyl Alcohol BP Ph Eur USP NF ACS Reagent Grade Manufacturers. (steunmijnclub.nl)
  • Description: FlexiSolv™ benzyl alcohol (BA) is a highly-refined, pure, aromatic, primary alcohol with a wide variety of applications as a solvent and chemical intermediate. (steunmijnclub.nl)
  • Addition of other aromatic molecules (e.g. benzene, toluene) and cyclohexene reduces the rate of the reduction of phenol, benzyl alcohol and cyclohexanones. (le.ac.uk)
  • Benzylalcohol is one of the simplest fatty alcohol containing phenyl. (steunmijnclub.nl)
  • It can be seen as benzene substituted by hydroxymethyl, or methyl alcohol substituted by phenyl. (steunmijnclub.nl)
  • The grouping ?6?5 - has the special name phenyl, but the compound C6H5OH is phenol, not phenyl alcohol. (powershow.com)
  • On the basis of product type global Phenylethyl market is sub-segmented as phenyl ethyl acetaldehyde, phenyl ethyl alcohol, phenyl ethyl formate, phenyl ethyl acetate, phenyl ethyl propionate, phenyl ethyl methyl ether, phenyl ethyl phenyl acetate, phenyl acetaldehyde dimethyl acetyl, phenyl ethyl methacrylate, and phenyl ethyl isobutyrate. (openpr.com)
  • Among the product type segment, phenyl ethyl alcohol contributes for the significant revenue share over the forecast period in global Phenylethyl market, owing to increasing demand for phenyl ethyl alcohol in the pharmaceutical industry. (openpr.com)
  • Cerebral responses after olfactory stimulation with phenyl ethyl alcohol - How much stimulation is necessary? (mpg.de)
  • presumably an accord with phenyl ethyl alcohol at the core. (badgerandblade.com)
  • The major chemical constituents of rose oil are citronellol, geranoil, nerol, linaloor and phenyl ethyl alcohol. (dst.gov.za)
  • 3. A composition according to claim 1 wherein said first alcohol a) is selected from the group consisting of cyclohexyl methanol, methylcyclohexanol, phenylethyl alcohol, 2-ethyl-1-hexanol, 3-cyclohexyl-1-propanol, and mixtures thereof. (google.com.au)
  • 4. A composition according to claim 1 wherein said first alcohol a) is cyclohexyl methanol. (google.com.au)
  • 18. A composition according to claim 15 wherein said second alcohol is methanol. (google.com.au)
  • 41 . The solution of claim 1 , wherein the alcohol is methanol. (google.ca)
  • In this report, the global Phenylethyl market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022. (absolutereports.com)
  • The global Phenylethyl market is expected to have substantially high growth rate, attributed to growing pharmaceutical industry across the globe. (openpr.com)
  • North America accounts for significantly high revenue share in global Phenylethyl market, attributed to robust marketing and research in the region. (openpr.com)
  • The growth of global Phenylethyl market is driven by growing pharmaceutical industry and innovation. (openpr.com)
  • The macroeconomic factor responsible for the growth of global Phenylethyl market is rising disposable income, the rapid rate of urbanization, and changing lifestyle of consumers. (openpr.com)
  • The key factor restraining the global Phenylethyl market is the harmful effect of Phenylethyl on the cardiovascular system. (openpr.com)
  • Basically, global Phenylethyl market is segmented on the basis of product type, application, and region. (openpr.com)
  • On the basis of end-use, the global Phenylethyl market is sub-segmented as pharmaceuticals, research institutes, and others, wherein pharmaceuticals segment contribute comparatively high revenue share. (openpr.com)
  • Based on the geographies, global Phenylethyl market is fragmented into seven key regions -- North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific except Japan, Japan, and the Middle East & Africa. (openpr.com)
  • Among the aforementioned regions, North America accounts for a significant share of global Phenylethyl market, owing to relatively high-value share of the region in the global pharmaceutical industry. (openpr.com)
  • Western Europe is followed by North America region in global Phenylethyl market. (openpr.com)
  • The Asia-Pacific except Japan region accounts for significantly high volume share in global Phenylethyl market, owing to the substantial growth in the pharmaceutical industry in the region. (openpr.com)
  • Eastern Europe and Japan also accounts for significant value share in global Phenylethyl market. (openpr.com)
  • The developing economy such as Middle East Africa and Latin America have a moderate opportunity in global Phenylethyl market, owing to the moderate growth rate in the pharmaceutical industry and growing population. (openpr.com)
  • Overall, the outlook for global Phenylethyl market will have a positive growth over the forecast period, owing to the increasing demand for the pharmaceuticals as an anti-counterfeiting measure. (openpr.com)
  • Few players in global Phenylethyl market include Kdac Chem Pvt. (openpr.com)
  • 42 . The solution of claim 1 , wherein the alcohol is ethanol or propylene glycol. (google.ca)
  • Ethyl Glucuronide (ETG) is a metabolite of ethyl alcohol which is formed in the body by glucuronidation following exposure to ethanol, such as by drinking alcoholic beverages. (xxjcy.com)
  • Practically, there are no studies on the use of the three types of whey, as a substrate of micro-organisms for the production of phenylethyl alcohol (PEA). (edu.mx)
  • We have applied pooled-segregant whole-genome sequence analysis to identify novel Saccharomyces cerevisiae genes affecting production of phenylethyl acetate (2-PEAc). (asm.org)
  • Dymista (azelastine hydrochloride and fluticasone propionate) nasal spray, 137 mcg / 50 mcg contains 0.1% solution of azelastine hydrochloride and 0.037% suspension of micronized fluticasone propionate in an isotonic aqueous suspension containing glycerin, microcrystalline cellulose and carboxymethylcellulose sodium, phenylethyl alcohol (2.5 mg/g), edetate disodium, benzalkonium chloride (0.1 mg/g), polysorbate 80, and purified water. (rxlist.com)
  • FLONASE Nasal Spray also contains microcrystalline cellulose and carboxymethylcellulose sodium, dextrose , 0.02% w/w benzalkonium chloride, polysorbate 80, and 0.25% w/w phenylethyl alcohol, and has a pH between 5 and 7. (rxlist.com)
  • Phenethyl alcohol, or 2-phenylethanol, is the organic compound that consists of a phenethyl group (C6H5CH2CH2) attached to OH. (wikipedia.org)
  • Phenethyl alcohol is prepared commercially via two routes. (wikipedia.org)
  • Hydrogenation of styrene oxide also affords phenethyl alcohol. (wikipedia.org)
  • Phenethyl alcohol can also be prepared by the reaction between phenylmagnesium bromide and ethylene oxide: C6H5MgBr + CH2CH2O → C6H5CH2CH2OMgBr C6H5CH2CH2OMgBr + H+ → C6H5CH2CH2OH Phenethyl alcohol can also be produced by biotransformation from L-phenylalanine using immobilized yeast Saccharomyces cerevisiae. (wikipedia.org)
  • It is also possible to produce phenethyl alcohol by the reduction of phenylacetic acid using sodium borohydride and iodine in THF. (wikipedia.org)
  • The pheromone bouquet contained aromatics (phenol, guaiacol, veratrole) and two major substances z-3-nonen-1-ol and phenylethyl alcohol. (uni-halle.de)
  • The main volatile compounds were ethyl acetate, phenylethyl alcohol, butanedioic acid diethyl ester, and hexadecane. (hindawi.com)
  • Name Tadalafil Appearence White crystalline powder Cas 171596-29-5 Assay ≥ 99 .5% Solubility Insoluble in water or alcohol , soluble in Acetic acid, ethyl ester Melting point 300-303°C Loss on drying ≤0.5% Heavy Metal ≤10ppm. (xxjcy.com)
  • Phenylethyl Alcohol Blood Agar (PEA) is an enriched selective medium used for the inhibition of facultative gram-negative rods and to inhibit the swarming of certain Clostridium species and Proteus species from clinical specimens. (anaerobesystems.com)
  • It is recommended that selective media such as Brucella Laked Blood Agar with Kanamycin and Vancomycin (LKV, catalog #: AS-112) and/or Brucella Blood Agar with Phenylethyl Alcohol (PEA, catalog #: AS-113) also be inoculated from clinical specimens to prevent such overgrowth and thus provide isolated colonies. (anaerobesystems.com)
  • The company providing the Phenylethyl have significantly high opportunity in regions such as North America, Europe, and Asia-Pacific, owing to the significant demand for Phenylethyl with rising demand for pharmaceuticals in the regions. (openpr.com)
  • Phenylethyl Alcohol, Reagent is a widely naturally occurring aromatic alcohol that is found in a range of essential oils including rose, orange blossom, champaca and others. (spectrumchemical.com)
  • Phenylethyl is a chemical compound derived from ethylbenzene by removing one hydrogen atom from the side chain. (openpr.com)
  • 2). Addition of hydrogen to the unsaturation, producing the saturated alcohol, is also observed for all the oxygenated compounds tried, and in the absence of acid this appears to be the major reaction. (le.ac.uk)
  • All ethyl alcohol 99 9 wholesalers & ethyl alcohol 99 9 manufacturers come from members. (xxjcy.com)
  • This, along with phenylethyl Resorcinol and allantoin are capable of removing a layer of dark skin and sterilize it. (weebly.com)
  • SymWhite TM (Phenylethyl Resorcinol) is an effective skin brightener and antioxidant containing potent levels of tyrosinase inhibition. (maralevarrebeauty.com)
  • Rose essence like the one present in Rose Shot, has more rosy alcohols that are top notes (mainly citronellol and geraniol), while rose absolute is composed mostly of heart notes (phenyl ethyl alcohol). (olfactivestudio.com)
  • Industrial alcohol is distilled ethyl alcohol (C2H5OH), normally of high proof, produced and sold for other than beverage purposes. (niir.org)
  • It is usually distributed in the form of pure ethyl alcohol, completely denatured alcohol, especially denatured alcohol and proprietary solvent blends. (niir.org)
  • Ethyl Alcohol is the common name for the hydroxyl derivative of the hydrocarbon ethane .Industrial alcohol is distilled ethyl alcohol normally of high proof, produced and sold for other than beverage purposes. (niir.org)
  • Ethyl alcohol or ethanol ranks second only to water as the most widely used solvent in chemical industry and as these industries have expanded, so the demand for industrial alcohol has increased. (niir.org)
  • Moisturizer â This beauty product has natural emollients and humectants: glycerine, pentylene glycol, Capric triglycerides, cetearly alcohol and sodium PCA. (weebly.com)
  • The percent of phenylethyl alcohol is not as high in the Otto as it is in the absolute. (atlanticinstitute.com)
  • A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. (drugbank.com)
  • This handbook on Industrial alcohol technology provides complete details on process and the technology used in the production of ethanol from various sugar crops and cereals and also briefs the different types of monohydric, trihydric and polyhydric alcohols. (niir.org)
  • Certain items considered to be hazardous materials including aerosols and alcohol-based products (i.e. pressurized cans, hair spray, mousses, nail polish, perfume, etc...) are required by the U.S. Department of Transportation to be shipped by ground only. (probeautyonline.com)
  • Industrial alcohol finds its applications in many chemical industries, pharmaceutical industries, Ink Industries and various allied applications. (niir.org)