Excipients: Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.Tablets: Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)Pharmaceutical Preparations: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.Powders: Substances made up of an aggregation of small particles, as that obtained by grinding or trituration of a solid drug. In pharmacy it is a form in which substances are administered. (From Dorland, 28th ed)Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.Flow Injection Analysis: The analysis of a chemical substance by inserting a sample into a carrier stream of reagent using a sample injection valve that propels the sample downstream where mixing occurs in a coiled tube, then passes into a flow-through detector and a recorder or other data handling device.Cellulose: A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.Potentiometry: Solution titration in which the end point is read from the electrode-potential variations with the concentrations of potential determining ions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Pharmaceutical Solutions: Homogeneous liquid preparations that contain one or more chemical substances dissolved, i.e., molecularly dispersed, in a suitable solvent or mixture of mutually miscible solvents. For reasons of their ingredients, method of preparation, or use, they do not fall into another group of products.Dosage Forms: Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect.Promazine: A phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.Calibration: Determination, by measurement or comparison with a standard, of the correct value of each scale reading on a meter or other measuring instrument; or determination of the settings of a control device that correspond to particular values of voltage, current, frequency or other output.Pharmaceutical Preparations, Dental: Drugs intended for DENTISTRY.Spectrophotometry, Ultraviolet: Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Electrodes: Electric conductors through which electric currents enter or leave a medium, whether it be an electrolytic solution, solid, molten mass, gas, or vacuum.Formic Acid EstersCrown Ethers: Macrocyclic polyethers with the repeating unit of (-CH2-CH2-O)n where n is greater than 2 and some oxygens may be replaced by nitrogen, sulfur or phosphorus. These compounds are useful for coordinating CATIONS. The nomenclature uses a prefix to indicate the size of the ring and a suffix for the number of heteroatoms.Polyvinyl Chloride: A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.Indicators and Reagents: Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)Drug Contamination: The presence of organisms, or any foreign material that makes a drug preparation impure.Drug Stability: The chemical and physical integrity of a pharmaceutical product.Chromatography, High Pressure Liquid: Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.Cerium: An element of the rare earth family of metals. It has the atomic symbol Ce, atomic number 58, and atomic weight 140.12. Cerium is a malleable metal used in industrial applications.Polarography: An electrochemical technique for measuring the current that flows in solution as a function of an applied voltage. The observed polarographic wave, resulting from the electrochemical response, depends on the way voltage is applied (linear sweep or differential pulse) and the type of electrode used. Usually a mercury drop electrode is used.Limit of Detection: Concentration or quantity that is derived from the smallest measure that can be detected with reasonable certainty for a given analytical procedure.Capsules: Hard or soft soluble containers used for the oral administration of medicine.Electrochemistry: The study of chemical changes resulting from electrical action and electrical activity resulting from chemical changes.Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Spectrophotometry: The art or process of comparing photometrically the relative intensities of the light in different parts of the spectrum.ThiazinesChemistry Techniques, Analytical: Methodologies used for the isolation, identification, detection, and quantitation of chemical substances.Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Membranes, Artificial: Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Reference Standards: A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.Carbon: A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel.Freeze Drying: Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.Anti-Inflammatory Agents, Non-Steroidal: Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Wettability: The quality or state of being wettable or the degree to which something can be wet. This is also the ability of any solid surface to be wetted when in contact with a liquid whose surface tension is reduced so that the liquid spreads over the surface of the solid.Emulsifying Agents: SURFACE-ACTIVE AGENTS that induce a dispersion of undissolved material throughout a liquid.Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Plant Preparations: Material prepared from plants.Anti-Obesity Agents: Agents that increase energy expenditure and weight loss by neural and chemical regulation. Beta-adrenergic agents and serotoninergic drugs have been experimentally used in patients with non-insulin dependent diabetes mellitus (NIDDM) to treat obesity.Diethylpropion: A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)Appetite Depressants: Agents that are used to suppress appetite.Phentermine: A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.Fenfluramine: A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.Dexfenfluramine: The S-isomer of FENFLURAMINE. It is a serotonin agonist and is used as an anorectic. Unlike fenfluramine, it does not possess any catecholamine agonist activity.

*Gentisic acid

... gentisic acid is readily oxidised and is used as an antioxidant excipient in some pharmaceutical preparations. In the ...

*Pharmacopoeia of the People's Republic of China

... biochemical preparations, Radiopharmaceuticals and excipients for pharmaceutical use; Volume III contains biological products ... "compendium of almost all traditional Chinese medicines and most western medicines and preparations. Information is given for ... single ingredient of Chinese crude drug preparations etc.; Volume II deals with monographs of chemical drugs, antibiotics, ...

*Ethylenediamine

When used as a pharmaceutical excipient, after oral administration its bioavailability is about 0.34, due to a substantial ... Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact ... Zuidema J. (1985-08-23). "Ethylenediamine, profile of a sensitizing excipient". Pharmacy World & Science. 7 (4): 134-40. doi: ...

*European Directorate for the Quality of Medicines

The EDQM implements a quality evaluation programme for active pharmaceutical ingredients (APIs) and excipients used in the ... and was expanded in 2003 to include herbal drugs and herbal drug preparations. It aims to evaluate whether the relevant ... In order to face this challenge, the European Committee on Pharmaceuticals and Pharmaceutical Care, co-ordinated by the EDQM, ... Setting quality and safety standards in pharmaceutical practices and pharmaceutical care: Public authorities and the sectors of ...

*Martindale: The Complete Drug Reference

... pharmaceutical excipients, vitamins and nutritional agents, vaccines, radiopharmaceuticals, contrast media and diagnostic ... Preparations - including over 180,000 items from 43 countries and regions, including China. Directory of Manufacturers listing ... Pharmaceutical Terms in Various Languages: this index lists nearly 5,600 pharmaceutical terms and routes of administration in ... Martindale: The Complete Drug Reference is a reference book published by Pharmaceutical Press listing some 6,000 drugs and ...

*List of MeSH codes (D15)

... pharmaceutical MeSH D26.650.931 --- vehicles MeSH D26.650.931.419 --- excipients MeSH D26.776.210 --- contact lens solutions ... delayed-action preparations MeSH D26.255.210.315 --- drug implants MeSH D26.255.210.860 --- tablets, enteric-coated MeSH ... pharmaceutical solutions MeSH D26.255.775.645 --- ophthalmic solutions MeSH D26.255.779 --- powders MeSH D26.255.785 --- ... pharmaceutical solutions MeSH D26.776.708.160 --- cardioplegic solutions MeSH D26.776.708.322 --- dialysis solutions MeSH ...

*Pharmaceutical formulation

This means that simple preparations are developed initially for use in phase I clinical trials. These typically consist of hand ... Pesticide formulation Drug development Dosage form Drug delivery Excipient, an inactive carrier Drug design Drug discovery ... Journal of Pharmaceutical Sciences 90 (10), 1620-1627. Chang, B.S. and Hershenson, S. 2002. Practical approaches to protein ... Comparison Table of Pharmaceutical Dosage Forms FDA database for Inactive Ingredient Search for Approved Drug Products. ...

*Drug reference standard

... s are highly characterized physical specimens used in testing by pharmaceutical and related industries ... Drug reference Standards are highly characterized specimens of drug substances, excipients, reportable impurities, degradation ... a reference standard provides a calibrated level of biological effects against which new preparations of the drug can be ... to help ensure the identity, strength, quality, and purity of medicines (drugs, biologics, and excipients), dietary supplements ...

*Generic drug

937: Annex 7 (pdf) WHO Expert Committee on Specifications for Pharmaceutical Preparations, Fortieth Report (WHO Technical ... Accessed 2008-06-15 Page, A; Etherton-Beer, C (January 2018). "Choosing a medication brand: Excipients, food intolerance and ... When a pharmaceutical company first markets a drug, it is usually under a patent that, until it expires, the company can use to ... Pharmaceutical companies that develop new drugs generally only invest in drug candidates with strong patent protection as a ...

*Tablet (pharmacy)

Handbook of Pharmaceutical Excipients. 3rd Edition ed. 2000, American Pharmaceutical Association & Pharmaceutical Press: ... Earlier medical recipes, such as those from 4000 BC, were for liquid preparations rather than solids. The first references to ... Pharmaceutical tablet presses are required to be easy to clean and quick to reconfigure with different tooling, because they ... The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient ...

*Outline of clinical research

Clinical research is the aspect of biomedical research that addresses the assessment of new pharmaceutical and biological drugs ... Food and Drug Administration or the European Medicines Agency Excipient - an inactive substance used as a carrier for the ... the biological equivalence of two preparations of a drug Pharmacodynamics - the study of the biochemical and physiological ... a submission to the FDA by a pharmaceutical company for review and approval of a new drug Abbreviated New Drug Application - a ...

*Dipyridamole

The Pharmaceutical Press. ISBN 0-85369-424-9. De Schryver EL, Algra A, van Gijn J (2007). Algra A, ed. "Dipyridamole for ... Modified release preparations are buffered and absorption is not affected. However, it is not licensed as monotherapy for ... http://emc.medicines.org.uk/medicine/304/SPC/Persantin+Retard+200mg/#EXCIPIENTS Stockley, Ivan (2009). Stockley's Drug ... Full Prescribing Information" (PDF). Boehringer Ingelheim Pharmaceuticals, Inc. Retrieved 1 December 2016. Nielsen-Kudsk, F; ...

*British Pharmacopoeia

A World Health Organization (WHO) INN identifies a pharmaceutical substance or active pharmaceutical ingredient by a unique ... Volume III Formulated Preparations Blood related Preparations Immunological Products Radiopharmaceutical Preparations Surgical ... excipients, and formulated preparation, together with supporting General Notices, Appendices (test methods, reagents etc.), and ... In 1907, the British Pharmacopoeia was supplemented by the British Pharmaceutical Codex, which gave information on drugs and ...

*Polyorthoester

Therefore, it must be stabilized by adding an alkaline pharmaceutical excipient when used as an implant material. The ... In toxicity tests as specified in the US Pharmacopeia USP polyorthoester preparations were found to be acutely nontoxic in ... Polyorthoester type IV avoids the addition of acidic excipients required in polyorthoester type II, which often diffuse ... Biodegradable Polymers as Drug Delivery Systems, in Drugs and the Pharmaceutical Sciences, 45, Marcel Dekker, Inc., ISBN 0-8247 ...

*Polysorbate 80

It is also used as an excipient in some European and Canadian influenza vaccines. Influenza vaccines contain 25 μg of ... "Pharmaceutical amiodarone composition for parenteral delivery". Retrieved 2008-04-06. Pandemic H1N1 (pH1N1) Influenza Vaccine ... used as an emulsifier in powdered drink preparations such as hot cocoa mix Polysorbate 65 Merck Index, 13th Edition, 7664. Chou ... Polysorbate 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and ...

*List of MeSH codes (D16)

... pharmaceutical MeSH D27.720.744.931 --- vehicles MeSH D27.720.744.931.419 --- excipients MeSH D27.720.777.300 --- chemical ... hair preparations MeSH D27.720.269.430.430 --- hair dyes MeSH D27.720.269.583 --- mouthwashes MeSH D27.720.269.700 --- perfume ... delayed-action preparations MeSH D27.720.280.210.315 --- drug implants MeSH D27.720.280.210.860 --- tablets, enteric-coated ... pharmaceutical solutions MeSH D27.720.280.775.322 --- cardioplegic solutions MeSH D27.720.280.775.483 --- dialysis solutions ...

*Vaccine

... the following excipients and residual manufacturing compounds are present or may be present in vaccine preparations: Aluminum ... Pharmaceutical firms and biotechnology companies have little incentive to develop vaccines for these diseases, because there is ... Department of Health and Human Services on US Influenza Vaccine Supply and Preparations for the Upcoming Influenza Season ...

*Starch

In the pharmaceutical industry, starch is also used as an excipient, as tablet disintegrant, and as binder. Resistant starch is ... Clothing or laundry starch is a liquid prepared by mixing a vegetable starch in water (earlier preparations also had to be ...

*Compounding

Pharmaceutical compounding (done in compounding pharmacies) is the creation of a particular pharmaceutical product to fit the ... Pharmacists were trained to compound the preparations made by the drug companies, but they could not do it efficiently on a ... but they can be particularly conducive to custom formulation with various possible excipients, in addition to custom drug/dose ... Pharmaceutical compounding is a branch of pharmacy that continues to play the crucial role of drug development. Compounding ...

*Aspartame

ISBN 978-0-911910-28-5. Rowe, Raymond C. (2009). "Aspartame". Handbook of Pharmaceutical Excipients. pp. 11-12. ISBN 1-58212- ... such as pharmaceutical preparations, fruit drinks, and chewing gum among others in smaller quantities. A 12 US fluid ounce (355 ... "Inactive" Ingredients in Pharmaceutical Products: Update (Subject Review)". Pediatrics. 99 (2): 268-78. 1997. doi:10.1542/peds. ... pharmaceutical drugs and supplements, shake mixes, tabletop sweeteners, teas, instant coffees, topping mixes, wine coolers and ...

*Discovery and development of proton pump inhibitors

Most oral PPI preparations are enteric-coated, due to the rapid degradation of the drugs in the acidic conditions of the ... The advantage is the pharmaceutical formulation of the drug, which is based on a dual release technology, with the first quick ... of pantoprazole was switched to the sodium salt which is more stable and has better compatibility with other excipients used in ... Oral esomeprazole preparations are enteric-coated, due to the rapid degradation of the drug in the acidic condition of the ...

*Caffeine

Excipients and Related Methodology, volume 33: Critical Compilation of pKa Values for Pharmaceutical Substances. Academic Press ... Bempong DK, Houghton PJ, Steadman K (1993). "The xanthine content of guarana and its preparations". Int J Pharmacog. 31 (3): ... Manufacturers of caffeine tablets claim that using caffeine of pharmaceutical quality improves mental alertness.[citation ... large amounts of caffeine with small amounts of theobromine and theophylline in a naturally occurring slow-release excipient. ...
Wholesale Pharmaceutical Tablets Supplier india - Online Pharmaceutical Tablets & Pharma Tablets Catalog, Pharmaceutical Tablets Suppliers Company, Pharmaceutical Tablets Wholesalers, Pharma Tablets Supplier, Wholesale Pharmaceutical Tablets, Wholesale Pharma Tablets Supplies, indian Pharma Tablets Suppliers.
1. NAME OF THE MEDICINAL PRODUCT. Cardicor 1.25 mg film-coated tablets. Cardicor 2.5 mg film-coated tablets. Cardicor 3.75 mg film-coated tablets. Cardicor 5 mg film-coated tablets. Cardicor 7.5 mg film-coated tablets. Cardicor 10 mg film-coated tablets. 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. Cardicor 1.25 mg: Each tablet contains 1.25 mg bisoprolol hemifumarate Cardicor 2.5 mg: Each tablet contains 2.5 mg bisoprolol hemifumarate Cardicor 3.75 mg: Each tablet contains 3.75 mg bisoprolol hemifumarate Cardicor 5 mg: Each tablet contains 5 mg bisoprolol hemifumarate Cardicor 7.5 mg: Each tablet contains 7.5 mg bisoprolol hemifumarate Cardicor 10 mg: Each tablet contains 10 mg bisoprolol hemifumarate For thea full list of excipients, see section 6.1. 3. PHARMACEUTICAL FORM. Film-coated tablet.. Cardicor 1.25 mg white, round film-coated tablets. Cardicor 2.5 mg white, heart-shaped, scored and film-coated tablets. Cardicor 3.75 mg off-white, heart-shaped, ...
Get online Pharmaceutical Tablets, We SAINTROY LIFESCIENCE are one of the trusted exporter, distributor, supplier & trader of Pharmaceutical Tablets based in Surat, Gujarat, India
Biovaxia Pharma | Pharmaceutical Tablet and Injections - Manufacturer of Pharmaceutical Tablet, Generic Tablets and Nutraceuticals Manufacturer from Chandigarh
Hilbert Healthcare | Pharmaceutical Tablets and Capsules - Wholesale Trader of Pharmaceutical Syrups, Pharmaceutical Syrup and Pharmaceutical Tablets from Chandigarh
We,Adsila Organics Private Limited is one of the WHO GMP, GLP and ISO 9001:2015 leading Trader, Supplier and Manufacturer of Pharmaceutical Tablet, We not only assure quality, but also timely delivery of the Pharmaceutical Tablet from Bahalgarh, Sonipat, Haryana, India
PROMETHAZINE HYDROCHLORIDE TABLETS, USP ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TABLETS, USP TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. RESPIRATORY DEPRESSION AND APNEA, SOMETIMES ASSOCIATED WITH DEATH, ARE STRONGLY ASSOCIATED WITH PROMETHAZINE PRODUCTS AND ARE NOT DIRECTLY RELATED TO INDIVIDUALIZED WEIGHT-BASED DOSING, WHICH MIGHT OTHERWISE PERMIT SAFE ADMINISTRATION. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DESPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. THE EXTRAPYRAMIDAL SYMPTOMS WHICH CAN OCCUR SECONDARY TO PROMETHAZINE HYDROCHLORIDE TABLETS, USP ADMINISTRATION MAY ...
Manufacturer of Pharmaceutical Tablets - Citicoline And Piracetam Tablets, Glimepiride Pioglitazone HCI And Metformin HCL SR Tablets, Deflazacort Tablets and Levofloxacin Tablet IP offered by Alencure Biotech Private Limited, Nahan, Himachal Pradesh.
Wholesale Trader of Pharmaceutical Tablets - Rabeprazole Sodium Tablets IP, Calcium and Vitamin D3 Tablets USP, Levocetirizine Tablets IP and Levocetirizine HCI And Ambroxol HCI Tablets offered by Asgard Labs Private Limited, Chandigarh.
According to a latest market report published by Persistence Market Research, titled "Global Market Study on Pharmaceutical Excipients: Increased Drug Demand in Emerging Asia Pacific Market to Fuel Demand Multi-Functional Excipients", revenue from the global pharmaceutical excipients market is expected to expand at a CAGR of 6.7% during the forecast period 2015 - 2021.. In the report, the global pharmaceutical excipients market is analyzed on the basis of chemistry type (i.e. source of origin), application type, functionality, and region. Based on chemistry type, the overall market has been segmented into plant-based, animal-based, mineral-based and synthetically derived excipients. Based on functionality, the market has been segmented into binders (binders, coatings, and fillers), glidents, diluents, disintegrants, and ...
Pharmaceutical Tablets Phentermine Hydrochloride Tablets Methylphenidate Hydrochloride Tablets Oxymorphone Hydrochloride Tablets Onax Alprazolam Tablets Gabapentin Tablets Clonazepam Tablets Hidrocloruro Trihydrate Tablets Ephedrine Hydrochloride Tablets Methadone Hydrochloride Tablets Hydromorphone Hydrochloride
Most study participants fulfilled ACR criteria for knee osteoarthritis,10 illustrating that this is a common and underdiagnosed condition within the community. The use of two combination tablets of ibuprofen/paracetamol was associated with significant improvements in pain relief, function and patient quality of life compared with paracetamol monotherapy for both short and long-term use. A significantly greater proportion of patients taking two combination tablets were responders at day 10 compared with paracetamol monotherapy, but not at study end. The level of absolute pain reduction achieved with one or two combination tablets was modest but of an order considered clinically relevant.32 33 The dose of ibuprofen used in this study was moderate, reflecting the non-prescription dose, the observed improved efficacy with the combination could therefore be due to paracetamol adding further cyclooxygenase inhibition to that provided by ibuprofen alone.. This combination tablet is designed for ...
Webinar: Introducing the Co-processed Excipient Guide! Friday, December 15, 2017 - 11:00am to 12:00pm EST Featuring Joseph Zeleznik, Manager of Technical & Regulatory Affairs, Meggle USA, Inc., and Chair, IPEC-Americas QbD Committee Description IPEC-Americas and IPEC Europe have jointly published a guide for excipient makers and users on co-processed excipients. This guide offers best practice and voluntary guidance on the development, manufacture and use of co-processed excipients and provides support to both manufacturers and users of co-processed excipients. Webinar Objectives: ...
In order to develop the enhanced understanding necessary to demonstrate an acceptable Design Space and Control Strategy required for Quality by Design (QbD) marketing applications, it will be necessary to incorporate the variability in potentially critical excipient parameters into the Design of Experiments (DoE). Methods are described that allow samples to be engineered such that potentially critical excipient parameters can be included in the DoE. However, it must be acknowledged that not all such excipient parameters will be amenable to sample engineering. The excipient manufacturer may be able to provide non-GMP samples which help define the necessary limits for the formulation. The nature of QbD as it relates to excipients is such that communication under a confidentiality agreement between excipient users and excipient makers will be necessary. The necessity for good communication between the excipient user and manufacturer is also emphasized.. ...
Global Market Study on Pharmaceutical Excipients: Pharmaceutical excipients are substances other than pharmacologically active drug components, which are included in the drug manufacturing process or contained in a finished pharmaceutical product dosage form.
Data & statistics on Chinese Pharmaceutical Excipients: 1504 310 ความรูพื้นฐานทางเภสัชภัณฑ หนวยกิต 4 (3-3-6) Fundamentals to Pharmaceutical Dosage Forms สาขาเภสัชศาสตร ชั้นปที่ 3 จํานวน 107 คน อ.ดร.จินตนา นภาพร และ อ.ดร.วริษฎา ศิลาออน ทุกวันศุกร เวลา 08.00-16.00 น. ศึ ก ษาความรู พื้ น ฐานทางเภสั ช ภั ณ ฑ ใ นด า นคุ ณ สมบั ติ ท างกายภาพและเคมี (Physicochemical properties) ของสารที่เปนยาและสารชวยทางเภสัชกรรม (Pharmaceutical excipients) ...
3. Why are excipients important in a drug product?For many reasons. Some, for example, comprise the products delivery system. These transport the active drug to the site in the body where the drug is intended to exert its action. Others will keep the drug from being released too early in the assimilation process in places where it could damage tender tissue and create gastric irritation or stomach upset. Others help the drug to disintegrate into particles small enough to reach the blood stream more quickly and still others protect the products stability so it will be at maximum effectiveness at time of use. In addition, some excipients are used to aid the identification of a drug product. Last, but not least, some excipients are used simply to make the product taste and look better. This improves patient compliance, especially in children. Although technically "inactive" from a therapeutic sense, pharmaceutical ...
The global pharmaceuticals excipients market is projected to post a phenomenal CAGR through 2022. The market is poised to rake in a healthy share of the revenue pie with robust growth of the pharmaceutical industry worldwide. Soaring uptake of oral and parenteral products owing to increasing occurrence of lifestyle and chronic disorders can escalate the growth of the market over the forecast period (2017 to 2022).. Browse Full Research Report With TOC On "Pharmaceutical Excipients Market Size, Report, 2017" at: https://www.radiantinsights.com/research/global-pharmaceutical-excipients-market-professional-survey-report-2017. Emergence of novel therapeutics, especially in the form of oral dispersible tablets, is one of the key factors driving the market. Surging use of functional excipients is likely to provide ...
These are just a few examples of many newer multifunctional or high-functioning excipients. Methods used to engineer these products include modification of particle size distribution by milling, seiving, agglomerating, spray drying, or roller compacting; selection of certain crystal polymorphic forms; cocrystallization, isolation of the crystal portion of the cellulose chain; modifications of the cooking process; modifications of the drying process; and nanosize water dispersion.2 Using multifunctional excipients simplifies the formulation process. Cost savings are not necessarily realized in reducing the amount of excipient used, which is a very small fraction of the cost of the tablet, but in reducing the total number of ingredients. Simple formulations are more straightforward to prepare, and fewer ingredients reduce the odds of adverse drug-excipient or excipient-excipient interactions. Multifunctional excipients are especially valuable in the ...
A microcrystalline cellulose-based excipient having improved compressibility, whether utilized in direct compression, dry granulation or wet granulation formulations, is disclosed. The excipient is an agglomerate of microcrystalline cellulose particles and from about 0.1% to about 20% silicon dioxide particles, by weight of the microcrystalline cellulose, wherein the microcrystalline cellulose and silicon dioxide are in intimate association with each other. The silicon dioxide utilized in the novel excipient has a particle size from about 1 nanometer to about 100 microns. Most preferably, the silicon dioxide is a grade of colloidal silicon dioxide.
Natural polysaccharides are drawing a great deal of attention in the recent years as excipient in the pharmaceutical industry. Due to the advances in drug delivery technology, natural polysaccharides are included in controlled drug delivery to fulfill multitask functions and in some cases directly or indirectly influence the extent and /or rate of drug release. In the present study, the polysaccharides extracted from Terminalia belarica gum (TBG) were evaluated for its safety and potency towards pre formulation studies as a pharmaceutical excipient. The study was undertaken with an objective to expound the physicochemical, thermal and functional properties of polysaccharide obtained from Terminalia belarica gum (TBG). A purified component of polysaccharide was isolated from Terminalia belarica gum (TBG) by gel filtration method. Elemental analysis, Scanning electron microscopy (SEM), X-ray diffraction spectroscopy (XRD), Differential ...
Excipients are used in most drug products and the quality of the materials, manufacturing processes, and test methods are vital to the production of safe, effective therapies. While industry guidances, excipient monographs, and compendial test methods provide some direction, sourcing and testing of excipients is an ongoing challenge for drug manufacturers.. A complex supply chain, raw materials quality concerns, and lot-to-lot and supplier-to-supplier variability are just some of the factors that can affect the consistency of excipient quality and performance. Routine testing of excipients, therefore, is crucial. Drug manufacturers must not only verify compendial test methods, but also assess the suitability of these test methods to meet the requirements of excipients, manufacturing processes, and analytical instruments currently used.. In this webcast, experts will review measures drug manufacturers must take to comply with regulatory ...
Press Release issued Jul 18, 2017: Taste masking techniques are applied to overcome or mask the unpleasant and bitter taste of active pharmaceutical ingredients to achieve patient acceptability and compliance. Oral administration of bitter and unpleasant tasting drugs is often the biggest challenge for pediatric and geriatric patient groups. Unless the active ingredient is tasteless or does not have any unpleasant taste, taste-masking plays a key role in the success of a final solid oral dosage form. The efficiency of taste-masking is often a key determinant for the success of specialized dosage forms like orally disintegrating tablets and films, and chewable tablets. The mechanisms of taste-masking techniques often rely on two major approaches the first is to add excipients like sweeteners, flavors, and effervescent agents to mask the unpleasant taste, and the second is to avoid the contact of bitter and unpleasant drugs with taste buds.
ALBANY, New York, November 7, 2012 /PRNewswire/ --. According to a new market report published by Transparency Market Research (http://www.transparencymarketresearch.com) "Excipients Market - Global Industry Analysis, Market Size, Share, Trends, Analysis, Growth and Forecast, 2012 - 2018," the global excipients demand was worth USD 5,260.0 million in 2011 and is expected to reach USD 7,586.6 million in 2018, growing at a CAGR of 5.4% from 2013 to 2018. Currently, Europe dominates the global market in terms of demand; however Asia Pacific is expected to be the most promising market in the near future mainly due to the availability of low cost products and cheap labor. The North America market for excipients in terms of revenue is growing at a CAGR of 5.3% from 2013 to 2018 as the U.S. has the biggest pharmaceutical market globally.. Browse the full report at ...
Croscarmellose Sodium Excipient - Sodium croscarmellose, or croscarmellose sodium, is an internally cross-linked sodium carboxymethylcellulose for use as a superdisintegrant in pharmaceutical formulations. E468 is the E number of crosslinked sodium carboxymethyl cellulose, used in food as an emulsifier.
0121] Pharmaceutical compositions according to the invention comprising at least one compound of the invention can comprise one or more pharmaceutical excipients. Examples of such excipients include, but are not limited to binding agents, filling agents, lubricating agents, suspending agents, sweeteners, flavoring agents, preservatives, buffers, wetting agents, disintegrants, effervescent agents, and other excipients. Such excipients are known in the art. Exemplary excipients include: (1) binding agents which include various celluloses and cross-linked polyvinylpyrrolidone, microcrystalline cellulose, such as Avicel® PH101 and Avicel® PH102, silicified microcrystalline cellulose (ProSolv SMCC®), gum tragacanth and gelatin; (2) filling agents such as various starches, lactose, lactose monohydrate, and lactose anhydrous; (3) disintegrating agents such as ...
Global microcrystalline cellulose market is expected to grow at a significant CAGR in the upcoming period as the scope and its applications are rising enormously across the globe. Microcrystalline cellulose (MCC) is a term used for refined wood pulp and is used as a bulking agent, a texturizer, an extender, an anti-caking agent, an emulsifier, and a fat substitute in food production. It is exclusively used in vitamin tablets or supplements and in plaque assays as a substitute to carboxymethyl cellulose. The factors that are playing a major role in the growth of microcrystalline cellulose (MCC) industry are the developing processed food industries across the globe, the rising pharmaceutical companies, and the acceptance of microcrystalline cellulose as a pharmaceutical excipient. However, the presence of alternatives for specific pharma and food & beverage applications may restrain the overall market in the years to come. Microcrystalline ...
0058]The stability of the capsules and pirfenidone/excipient formulations provided herein is demonstrated in the results presented in FIG. 8. The 267 mg pirfenidone capsule formulation of FIG. 6 was stored for 18 months under three different storage conditions: 25° C. and 60% relative humidity, 30° C. and 65% relative humidity, and 40° C. and 75% relative humidity. FIG. 8 shows that the dissolution of the capsule and pirfenidone/excipient formulations at 25° C. and 60% relative humidity, 30° C. and 65% relative humidity did not appreciably change over the duration of the 18 month period. The dissolution of the capsule and pirfenidone/excipient formulations at 40° C. and 75% relative humidity did not appreciably change over the initial 12 month period. The dissolution analysis was performed according to the pharmacopoeial dissolution method specified in USP29 using Apparatus 2 (paddles) with water as a solvent and a specification of Q=70% of label claim in 30 minutes. Also shown in FIG. 8, ...
TY - JOUR. T1 - Influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose with β-cyclodextrin. AU - Wu, J. S.. AU - Ho, H. O.. AU - Sheu, M. T.. PY - 2001. Y1 - 2001. N2 - The individual influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose (MCC) with β-cyclodextrin (β-CD) was examined in this study. Avicel PH 101 and 301 were included for comparison. The codried product, Avicel PH 101 and 301 were granulated with water, and the granules were milled to retain three different size fractions: 37-60 μm, 60-150 μm, and 150-420 μm. The original Avicels and codried product were lubricated with magnesium stearate in three different percentages (0.2, 0.5, and 1.0%). The results showed that the powder flowability and disintegration of codried product and Avicels were significantly improved after wet granulation. However, the compactibility of ...
According to a new market report published by Transparency Market Research "Excipients Market - Global Industry Analysis, Market Size, Share, Trends, Analysis, Growth and Forecast, 2012 - 2018," the global excipients demand was worth USD 5,260.0 million in 2011 and is expected to reach USD 7,586.6 million in 2018, growing at a CAGR of 5.4% from 2013 to 2018. Currently, Europe dominates the global market in terms of demand; however Asia Pacific is expected to be the most promising market in the near future mainly due to the availability of low cost products and cheap labor. The North America market for excipients in terms of revenue is growing at a CAGR of 5.3% from 2013 to 2018 as the U.S. has the biggest pharmaceutical market globally ...
Fractions from white and tannin sorghums were processed into extrudates, thick porridges, and breads. The effects of sorghum type and fraction on the in vitro starch availability of the products were evaluated, and the estimated glycemic indexes (EGI) of the products were obtained. Sorghum extrudates were significantly more slowly digested than corn meal extrudates for all preparation methods (whole, cracked and decorticated kernels). Furthermore, tannin extrudates were less digestible than white sorghum extrudates. The soft endosperm nature of the tannin sorghum limited friction formation inside the extruder, reducing starch gelatinization. On the other hand, condensed tannins also interfered with the starch availability for digestion. White sorghum was more suitable for extrusion, giving extrudates with higher starch degradation and expansion than the tannin sorghums. However, tannin sorghums also gave acceptable products offering the benefit of lower EGI values. Sorghum porridges were more ...
Marwaha, S.S.; Kennedy, J.F.; Sehgal, V.K., 1988: Simulation of process conditions of continuous ethanol fermentation of whey permeate using alginate entrapped Kluyveromyces marxianus NCYC 179 cells in a packed-bed reactor system
Contamination of bacteria in large-scale yeast fermentations is a serious problem and a threat to the development of successful biofuel production plants. Huge research efforts have been spent in order to solve this problem, but additional ways must still be found to keep bacterial contaminants from thriving in these environments. The aim of this project was to develop process conditions that would inhibit bacterial growth while giving yeast a competitive advantage. Lactic acid bacteria are usually considered to be the most common contaminants in industrial yeast fermentations. Our observations support this view but also suggest that acetic acid bacteria, although not so numerous, could be a much more problematic obstacle to overcome. Acetic acid bacteria showed a capacity to drastically reduce the viability of yeast. In addition, they consumed the previously formed ethanol. Lactic acid bacteria did not show this detrimental effect on yeast viability. It was possible to combat both types of bacteria by
Given the growing interest in the production of new and low cost bioemulsifiers, the rice and wheat bran and straw were investigated in this study for the production of bioemulsifier by Lactobacillus plantarum subsp. plantarum PTCC 1896 (probiotic). The strain produced bioemulsifier only in the rice bran hydrolysate medium. The bioemulsifier amount reached around 0.7 g L-1 for 72 hours of fermentation. The new biomolecule was extracted, purified, and its structural and thermal properties were evaluated. The functional groups and the structure of the molecule were revealed by GPC, FT-IR, 1HNMR and 13CNMR techniques. The bioemulsifier was a water soluble extracellular high molecular weight (|107 Da) α-glucan (81.74%) bound with protein (18.18%). Thermal behavior was studied using DSC and TG analysis. Thermal analysis showed the bioemulsifier broke down above 211.74°C, and the melting point was 182.0°C with the enthalpy value of 101.7 J g-1. These results might provide incentives for the industrial
Given the growing interest in the production of new and low cost bioemulsifiers, the rice and wheat bran and straw were investigated in this study for the production of bioemulsifier by Lactobacillus plantarum subsp. plantarum PTCC 1896 (probiotic). The strain produced bioemulsifier only in the rice bran hydrolysate medium. The bioemulsifier amount reached around 0.7 g L-1 for 72 hours of fermentation. The new biomolecule was extracted, purified, and its structural and thermal properties were evaluated. The functional groups and the structure of the molecule were revealed by GPC, FT-IR, 1HNMR and 13CNMR techniques. The bioemulsifier was a water soluble extracellular high molecular weight (|107 Da) α-glucan (81.74%) bound with protein (18.18%). Thermal behavior was studied using DSC and TG analysis. Thermal analysis showed the bioemulsifier broke down above 211.74°C, and the melting point was 182.0°C with the enthalpy value of 101.7 J g-1. These results might provide incentives for the industrial
The aim of this study is to apply wet granulation on liquisolid powders to overcome issues of poor powder flowability and compressibility especially with using high viscosity liquid vehicles. Different liquisolid formulations were made using three excipients where the effect of each excipient used in the dissolution of the model hydrophobic drug (Glibenclamide) was evaluated. The Glibenclamide tablets were formulated using PEG 400, Synperonic PE/L44 and Cremophor ELP, at a 10 %w/w in liquid vehicle drug concentration. The carrier (Avicel®PH102) was used followed by colloidal silicon dioxide (coating material) that converted the wet mixture into dry powder. Potato starch, 5%w/w, as a disintegrant was mixed with the mixture manually for 10 minutes and was finalized by adding 0.75% of magnesium stearate as a lubricant. The final powder (depending on its flowability and compactability) was then compacted automatically using a single-punch tableting machine to give tablets with 4mg unit drug ...
A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means. That is, by an intrinsic property of the drug formulation, rather than by special mixing and handling. It employs the familiar ouzo effect displayed by anethole in many anise-flavored liquors. Microemulsions have significant potential for use in drug delivery, and SMEDDS (including so-called "U-type" microemulsions) are the best of these systems identified to date. SMEDDS are of particular value in increasing the absorption of lipophilic drugs taken by mouth. SMEDDS in research or development include formulations of the drugs anethole trithione, oridonin, curcumin, vinpocetine, tacrolimus,Mitotane, berberine hydrochloride, nobiletin, piroxicam, anti-malaria drugs beta-Artemether and halofantrine, anti-HIV drug UC 781, nimodipine, exemestane, anti-cancer drugs 9-nitrocamptothecin (9-NC) paclitaxel, and seocalcitol, alprostadil (intraurethral ...
This report covers the present scenario and the growth prospects of the global solubility enhancement excipients market for OSDF for the period 2015-2019. To arrive at the market shares of vendors and to calculate the market size, the report considers the revenue generated from the sales of solubility enhancement excipients in OSDF. It also presents the vendor landscape and a corresponding detailed analysis of the top eight vendors in the market. In addition, the report has been segmented based on: type (lipids, polymers, surfactants, and others like cyclodextrins and ion exchange resins); technology (solid dispersion, particle size reduction, micellar solubilization, lipid solubilization, chemical modification, complexation, and others such as dendrimers, silica, and solid-lipid nanoparticles); and geography (the Americas, APAC, and EMEA). The report does not cover the technology segment (modification of crystals). ...
This report covers the present scenario and the growth prospects of the global solubility enhancement excipients market for OSDF for the period 2015-2019. To arrive at the market shares of vendors and to calculate the market size, the report considers the revenue generated from the sales of solubility enhancement excipients in OSDF. It also presents the vendor landscape and a corresponding detailed analysis of the top eight vendors in the market. In addition, the report has been segmented based on: type (lipids, polymers, surfactants, and others like cyclodextrins and ion exchange resins); technology (solid dispersion, particle size reduction, micellar solubilization, lipid solubilization, chemical modification, complexation, and others such as dendrimers, silica, and solid-lipid nanoparticles); and geography (the Americas, APAC, and EMEA). The report does not cover the technology segment (modification of crystals). ...
S(−)-Verapamil hydrochloride hydrate 36622-28-3 safety info, S(−)-Verapamil hydrochloride hydrate chemical safety search, Chemical S(−)-Verapamil hydrochloride hydrate safety technical specifications ect.
Take advantage of the opportunity to present your company, your products and services to your target group with hardly any scattering losses.
This years conference will take place in Prague, Czech Republic. Founded during the Romanesque and flourishing by the Gothic and Renaissance eras, Prague was not only the capital of the Czech state, but also the seat of two Holy Roman Emperors and thus also the capital of the Holy Roman Empire.
See on Scoop.it - Transparenc Market Research [108 Pages Premium Report] Pharma Excipients Market and Oral Solid Dosage Forms (OSDF) for Polymers (MCC, HPMC, CMC, Ethyl Cellulose, Povidone and Others), Alcohols (Glycerin, Sorbitol, Mannitol, Propylene Glycol), Minerals (Clay, Silicon Dioxide,...Transparency Market Researchs insight:Market Research Reports : Transparency Market Research published new market report Oral Solid…
A novel nifedipine-containing solid pharmaceutical preparation composition comprising a mixture of nifedipine and at least one 1st(a) substance selected from polyvinyl pyrrolidone, methyl cellulose, hydroxypropyl cellulose and hydroxypropylmethyl cellulose; a mixture of nifedipine, at least one 1st(b) substance selected from polyvinyl pyrrolidone, urea, citric acid mannitol, succinic acid, methyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose and amino acid, and at least one 2nd substance selected from a surface active agent, polyethylene glycol, propylene glycol, glycerol, a glycerol fatty acid ester and a vegetable oil; or a mixture of nifedipine, the 1st(b) substance, the 2nd substance and calcium lactate. The composition of this invention can increase the bioavailability of nifedipine and makes it possible to provide a nifedipine-containing pharmaceutical preparation which has small bulk and can be easily administered.
[159 Pages Report] Check for Discount on Global Solubility Enhancement Excipients for OSDF Industry 2016 Market Research Report report by QYResearch Group. The Global Solubility Enhancement Excipients for OSDF Industry 2016 Market...
Request sample of market research report on Cellulose Derivative Excipient Market. Explore detailed TOC, tables and figures of Cellulose Derivative Excipient Market.
Page contains details about etoposide-loaded non-cationic self-microemulsifying drug delivery system . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
A particulate coprocessed microcrystalline cellulose and calcium carbonate composition having the respective components present in a weight ratio of from about 75:25 to 35:65. The composition is useful as a pharmaceutical excipient. The coprocessed composition is prepared by forming a well-dispersed aqueous slurry of microcrystalline cellulose and calcium carbonate and then drying the slurry, preferably by spray drying, to yield a particulate product.
Driven by the rising demand for low-fat foods and the robust expansion of the global pharmaceutical excipient industry, the global microcrystalline cellulose market is expected to exhibit moderate growth over the period between 2014 and 2020. The report, titled "Microcrystalline Cellulose Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020", states that the market will expand at a 5.80% CAGR over the reports forecast period and rise from a valuation of US$632.9 mn in 2013 to US$936.3 mn by 2020 ...
Buy quality tableting machine price products from tableting machine price manufacturer, 21295 tableting machine price manufacturers & tableting machine price suppliers from China.
Study shows that adequate choice of the blending technique, e.g. using magnesium stearate as an excipient allows control of aerosol performance of a dry powder inhaler.
The successful synthesis of novel cholesteric hydroxypropyl cellulose (HPC) ester derivatives with pitch heights in the visible range and with functional thioether groups is reported here. The new methylthiopropionated HPC (HPC-MTP) was synthesized by the esterification of hydroxypropyl cellulose with 3-methylthiopropionyl chloride (MTP). Chain degradation and cross-linking of cellulose chains during esterification were avoided and complete esterification of all OH groups was achieved by the use of N,N-dimethylacetamide (DMAc) as the solvent. The structure of HPC-MTP was analyzed by NMR- and IR-spectroscopy and SEC. The physical properties of this new material were measured by TGA, DSC, wide angle X-ray scattering, polarization microscopy and UV/Vis spectroscopy. HPC-MTP products were found to be thermotropic liquid crystalline and formed cholesteric and nematic phases. The formation of lyotropic phases was observed with triglyme as the solvent.. ...
A sustained release matrix formulation for Albuterol Sulphate was designed and developed to achieve a 12 h release profile. Using HPMC K15M and HPMC K100M as an inert matrix forming agent to control the release of Albuterol Sulphate. The matrix tablets for these formulations were prepared by direct compression and their in-vitro release tests were carried out for a period of 12 hours using USP dissolution test apparatus (type II Paddle) at 37±0.5°C and 50 rpm speed. A 32 full factorial design was used for optimization by taking the concentration of HPMC K15M (X1) and HPMC K100M (X2) were selected as independent variables, whereas initial release at the (Y1, % drug release), (Y2, % drug Content) the concentration of Were chosen as dependent variables. The optimized formulation F1 follows Higuchi model and Korsemeyer - Pappas release kinetics with non- Fickian diffusion mechanism. From the study, it was concluded that the release of Albuterol Sulphate can be effectively controlled using ...
Amifull from Bionova, Hydroxypropyl methylcellulose - Aquaplus to Gonosol | Hydroxypropyl methylcellulose is indicated as an ophthalmic surgical aid in cataract extraction, IOL implantation and other anterior segment surgical procedures. Use of Amifull from Bionova, Pregnancy, lactation in childrens and special precautions for Amifull from Bionova, prices of Amifull from Bionova . During anterior segmental surgery, Hydroxypropyl methylcellulose maintain deep chamber and reduce less trauma to the ocular tissues and corneal endothelium. The viscous nature of Hydroxypropyl methylcellulose can prevent the formation of post-operative flat chamber., drugsupdate.com - Indias leading online platform for Doctors and health care professionals. Updates on Drugs, news, journals, 1000s of videos, national and international events, product-launches and much more...Latest drugs in India, drugs, drugs update, drugs update
Manufacturer of Active Pharmaceutical Ingredients By Alphabet H - Haloperidol, Hydrochlorothiazide, Hydrocortisone and Hyoscine Butyl Bromide offered by KPS Chemicals & Pharmaceuticals, Surat, Gujarat.
DRSP, EE as betadex clathrate, 0.451 mg levomefolate calcium, levomefolate calcium, lactose monohydrate NF, microcrystalline cellulose NF, croscarmellose, sodium NF, hydroxypropyl cellulose NF, magnesium stearate NF, hypromellose USP, titanium dioxide USP, talc USP, polyethylene glycol NF, ferric oxide pigment, red NF; are lactose monohydrate NF, microcrystalline, cellulose NF, croscarmellose sodium NF, hydroxypropyl cellulose NF, magnesium stearate NF, hypromellose USP, titanium dioxide USP talc USP, polyethylene glycol NF, ferric oxide pigment, red NF, ferric oxide pigment, yellow NF ...
Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems. GURRAM, A. K.; DESHPANDE, P. B.; KAR, S. S.; NAYAK, USHA Y.; UDUPA, N.; REDDY, M. S. // Indian Journal of Pharmaceutical Sciences;May/Jun2015, Vol. 77 Issue 3, p249 Pharmaceutical research is focused in designing novel drug delivery systems to improve the bioavailability of poorly water soluble drugs. Self-microemulsifying drug delivery systems, one among the lipid-based dosage forms were proven to be promising in improving the oral bioavailability of such... ...
Studies on a model ink suspension have shown that the effect of non-ionic dispersion agents on ink agglomeration using fatty acid chemistry as collector was highly temperature-dependent. The non-ionic surfactant reduced the agglomeration efficiency at low temperatures (below the cloud point of the surfactant) but this negative effect was reduced at increasing temperatures. At temperatures above the cloud point the non-ionic surfactant improved the agglomeration. The non-ionic surfactant adsorbs to both the ink and precipitated soap particles, which at low temperatures resulted in an increased colloidal stability of the particles but at higher temperatures led to a destabilisation of the particles due to the increased hydrophobicity of the surfactant. The surfactants clearly affected the precipitation of fatty acid anions to calcium soaps and at very high surfactant concentrations the formation of calcium soap particles was drastically reduced. The most favourable conditions seemed to be ...
A sustained-release tablet formulation should ideally have a proper release profile insensitive to moderate changes in tablet hardness that is usually encountered in manufacturing. In this study, matrix aspirin (acetylsalicylic acid) tablets with ethylcellulose (EC), Eudragit RS100 (RS), and Eudragit S100 (S) were prepared by direct compression. The release behaviors were then studied in two counterpart series of tablets with hardness difference of three Kp units, and compared by non-linear regression analysis. The release pattern for both the S-containing and RS-containing formulations fitted best in Higuchi model, and the proper equations were suggested. In the EC-containing formulation, Higuchi and also zero-order models were probable models for the release, and a combination equation for the release was suggested. In the S-containing formulation, the release profile was completely sensitive to the hardness change. In RS-containing series, the slope of the release graph did not change due to the
Lansoprazole 15 mg orodispersible tablets - Summary of Product Characteristics (SmPC) by Ranbaxy (UK) Limited a Sun Pharmaceutical Company
The suitability of the new isomalt grade galenIQ™ 801 for dry granulation and following tableting is evaluated in this study. Isomalt alone, as well as a blend of equal parts with dibasic calcium phosphate, is roll compacted and tableted. Particle size distribution and flowability of the granules and friability and disintegration time of the tablets are determined. Tensile strength of tablets is related to the specific compaction force during roll compaction and the tableting force. In all cases, the tensile strength increases with raising tableting forces. The specific compaction force has a different influence. For isomalt alone the tensile strength is highest for tablets made from granules prepared at 2 kN/cm and 6 kN/cm and decreases at higher values, i.e., >10 kN/cm. Tensile strength of the blend tablets is almost one third lower compared to the strongest tablets of pure isomalt. Friability of pure isomalt tablets is above the limit. Disintegration time is longest when the tensile strength
Magnesium stearate is widely used as an excipient in supplements, dietfood for medical purposes and drugs, because machines compressing tablets run more smooth if magnesium starate is added to tablets. Basically the addition of magnesium stearate has nothing to do with our body but all with the industriel proces of making tablets. Magnesium stearate is…
Abstract:. Aim and Objective: Solubility is the important physicochemical factors which affect the absorption of drug and therapeutic effectiveness. The poor solubility of drug substance in water and low absorption in aqueous GIT fluid leads to insufficient bioavailability. The purpose of present research work is to increase the aqueous solubility and dissolution rate of poorly water soluble drug. Materials and Method: Solubility of diflunisal enhanced by solid dispersion (kneading method) method using beta cyclodextrin as a carrier (also act as taste masking agent). Fast dissolving tablet of diflunisal was prepared by direct compression method using crospovidone as a superdisintigrant from optimized solid dispersion complexes. Prepared tablets were evaluated for various parameters: weight variation, hardness, friability, modified dispersion time, disintegration test, drug content and drug release. Results and conclusion: From the results obtained it has been concluded that prepared tablets from ...
Cellulose microcrystalline, referred as CEPO, is a widely used excipient, an inert substance used in many pill and tablet formulations. It is a white, odourless, tasteless, extra free flowing powder which is relatively free from organic and non-organic contaminants. The powder is metabolically inert, and has excellent water absorptive, swelling & dispersion properties, is insoluble in water, dilute acid, common organic solvents and oils.. It consists primarily of crystallite aggregates obtained by removing amorphous (fibrous cellulose) regions of a purified cellulose source material by hydrolytic degradation, typically with a strong mineral acid such as hydrogen chloride. The acid hydrolysis process produces a microcrystalline cellulose of predominantly coarse particulate aggregates, typically having a mean size range of about 15 to 40 microns.. Cellulose microcrystalline has many applications in pharmaceuticals, foods, papers and structural composites. It is a naturally ...
Spray-dried lactose is widely used as filler and binder in the pharmaceutical industry, but many adults are not able to di-gest lactose. Therefore, it is indispensable to provide alternatives to lactose-containing drugs in order to make them suitable for lac-tose intolerant patients. EMDEX® is a promising substitute for spray-dried lactose as it has similar powder and tableting pro-perties. The aim of this study was to test a lactose-free refor-mu-lation of cetirizine tablets. EMDEX® was used suc-cessfully as a lactose substitute in cetirizine tablets resul-ting in comparable tablet properties in terms of crushing strength, disintegration time and dissolution profile. Furthermore, the EMDEX® formu-lation was characterized by an excellent powder flow and low ejection forces during the tableting process.
Xanthan gum is a very effective thickener. It is stable under a wide range of temperatures and pH. Only 0.5% of xanthan gum is added to most foods to thicken them. The thickening property of xanthan gum decreases when a food is mixed, shaken or chewed, but it thickens up again when the force is removed. This property is called pseudoplasticity. Sometimes this property can be very useful. For instance, the xanthan gum added to salad dressing makes the dressing thick enough to cling to a salad, but shaking the bottle of dressing makes it temporarily thin and easier to pour.. Salad dressings and sauces contain xanthan gum. Even though xanthan gum is not an emulsifier, it helps to keep an emulsion stable so that the oil in it does not separate. Xanthan gum also helps to keep spices and other solid bits of food evenly distributed in a liquid. Xanthan gum, guar gum and locust bean gum help to give ice cream and other frozen foods a creamy texture. Gluten-free bakers use xanthan gum instead of gluten ...
Purpose To formulate hydroxypropyl methylcellulose-stabilized self-emulsifying solid dispersible carriers of noscapine to enhance oral bioavailability. Methods Formulation of noscapine (Nos) self-emulsifying solid dispersible microparticles (SESDs) was afforded by emulsification using an optimized formula of Labrafil M1944, Tween-80, and Labrasol followed by spray-drying with hydroxypropyl methylcellulose (HPMC), with and without mannosamine (Mann-Nos_SESDs and Nos_SESDs respectively); self-microemulsifying liquid dispersions (SMEDDs) with and without mannosamine (Mann-Nos_SMEDDs and Nos_SMEDDs respectively) were also prepared. SMEDDs and SESDs were characterized for size, polydispersity, surface charge, entrapment efficiency, in vitro permeability, in vitro release kinetics, and oral pharmacokinetics in Sprague-Dawley rats (10 mg/kg p.o). The antitumor efficacy of Mann-Nos_SESDs on the basis of chemosensitization to cisplatin (2.0 mg/kg, IV) was investigated in a chemorefractory lung tumor Nu/Nu
Clobetasol propionate ointment buy online / where can i buy clobetasol propionate ointment usp 0.05 / purchase clobetasol propionate online : They will get a slice it and it is one of amino acids, primarily from this is made from time you like.
Ultrasound and safely and hair loss has been proven link between what got the Society. A and make your health. Namely, that promise a relation to accurately judge their hair for symptoms. In case of which contains all plant - the excessive rubbing alcohol. Believe me, which work for those tresses will help cheap clobetasol propionate and disrupt bile pigments. Once you have to a prescription drugs clobetasol propionate of insufficient insulin and one look fantastic! This is absurd, how to remedy for the muscles. You see in the other however, have been overshadowed by detoxification of lost from oxidation process for the body in the prostate. If treatment program is no sperm, the desired results and that the hair easily, giving it can be accurate manual techniques are unique. Until you are many assets we think and are allowed the herbal shampoo.. To know that your hunger prescription drugs clobetasol propionate may feel that braces-wearing kids and your particular lady who have relatively ...
Press Release issued Mar 15, 2017: According to a research article published in world journal of pharmacy and pharmaceutical sciences, of all the tablets worldwide, over 90% of tablets are ingested by oral routes. Orally disintegrating tablets can be manufactured by many methods and techniques such as lyophilization or freeze drying, tablet molding, spray drying, mass-extrusion, phase transition, melt granulation, sublimation, cotton candy technology and direct compression method. Out of all the methods or technologies applied for production, direct compression method is the most preferred, cost-effective and also provides orally disintegrating tablets with adequate structural integrity. Of the total drug prescriptions, about two-third are dispensed as solid dosage forms, while 50 percent of these are dispensed as compressed tablets.
Summary of Facts and Submissions. I. European patent No. 1 257 280, based on European patent application No. 01900579.2, which was filed as an international application published as WO 01/52857, was granted with fifty-five claims.. Claim 1 as granted reads as follows:. 1. A pharmaceutical composition in the form of an oral dosage form comprising. i) an estrogen with exception of ethinyl estradiol;. ii) drospirenone in an amount corresponding to a daily dose ranging from 0.25 to 10 mg; and. iii) a pharmaceutically acceptable excipient or carrier,. wherein said drospirenone is in a form having a surface area of more than 10.000 cm**(2)/g.. Independent claim 2 as granted reads as follows:. 2. A pharmaceutical composition in the form of an oral dosage form comprising. i) an estrogen with the exception of ethinyl estradiol;. ii) drospirenone in an amount corresponding to a daily dose ranging from 0.25 to 10 mg; ...
This study was undertaken to explore gum from Bombax buonopozense calyxes as a binding agent in formulation of immediate release dosage forms using wet granulation method. The granules were characterized to assess the flow and compression properties and when compressed, non-compendial and compendial tests were undertaken to assess the tablet properties for tablets prepared with bombax gum in comparison with those prepared with tragacanth and acacia gums. Granules prepared with bombax exhibited good flow and compressible properties with angle of repose 28.60°, Carrs compressibility of 21.30% and Hausners quotient of 1.27. The tablets were hard, but did not disintegrate after one hour. Furthermore, only 52.5% of paracetamol was released after one hour. The drug release profile followed zero order kinetics. Tablets prepared with bombax gum have the potential to deliver drugs in a controlled manner over a prolonged period at a constant rate.
Ingredients: Tablet: Microcrystalline Cellulose, Calcium Ascorbate Prep. (Calcium Ascorbate, Hydroxypropyl Methyl Cellulose, Tartaric Acid), Vitamin E Prep. (Vitamin E, Maltodextrin, Modified Starch, Silicon Dioxide), Tablet Coat (Hydroxypropyl Cellulose, Hydroxypropyl Methyl Cellulose, Colours: Titanium Dioxide, Iron Oxide; Glycerol, Magnesium Stearate), Hydroxypropyl Cellulose, Niacinamide, Calcium Pantothenate, Biotin Prep. (Maltodextrin, Biotin), Vitamin B12 Prep. (Maltodextrin, Trisodium Citrate, Citric Acid, Vitamin B12), Magnesium Stearate, Vitamin B6, Vitamin B2, Vitamin B1, Calcium-L-Methylfolate, Folic Acid, Potassium Iodide ...
Carbopol 941, an acrylic acid polymer and "Eudragit L100-55, a metacylic acid polymer, were compared as sustained release matrix devices for theophylline hydrate tablets. The theophylline tablets containing 0 to 30% of either of the polymer were prepared using the direct compression method. In vitro drug release studies were carried out in 0.1 N HCl, simulated gastric fluid without pepsin (SGF) and simulated intestinal fluid without pancreatin (SIF). A relatively prolonged release of theophylline from the two polymer matrices for an 8 hr-release period was detected. At 20% w/w and in 0.1 N HCl there were no significant drug releases from the two matrices within the first 2 hrs; after this period, carbopol 941 exerted a more retardant effect on drug releases. At 30% w/w, release rate from Eudragit L100-55 was faster for a 6 hr period with a steady state release maintained at 50% for 4 hrs. The rates of theophylline release from the matrices depended on the pH of the dissolution media and on the ...
Xanthan gum is a kind of wild yellow microbial bacterium grinding into powder. It is made of glucose, mannose and glucuronic acid three interconnected to form cellulose sugar chains. The consistency of xanthan gum with corn starch, but more stable. Because is made from the fermentation bacteria, is also known as a kind of natural food. Xanthan gum is often used in food and nonfood items. The history of xanthan gum xanthan gum is found in the United States department of agriculture laboratory. In one test a variety of polymer of potential use in the project, it was found that this kind of material. For the first time in 1960, Kelco company produce business xanthan gum. In 1968, after the complete animal experiments, it has been approved for food use. The xanthan gum in food xanthan gum has the effect of thickening dairy and salad, keep food appearance consistency and liquidity. It is also used to keep the ice cream, low-fat and fat-free dairy products become more full, in addition, the xanthan ...
Buy clobetasol propionate ointment 0.05 / clobetasol propionate cream usp 0.05 over the counter / where can i buy clobetasol propionate foam : According to Rs.
Abstract The present article describes the recent role of polymers as carriers for delivery of drug at target site to extending its release. These polymers are widely used in delivery due to their inherent characteristics such as biocompatibility, biodegradability. Chitosan and Eudragit are choice of drug in extended release matrix tablets. Chitosan is an amino polysaccharide polymer which is biodegradable, biocompatibility and nontoxic nature. Due to its cationic nature, Chitosan form complex with anions like Eudragit giving rise to polyelectrolyte complexes. Chitosan enhances the dissolution of poor soluble drugs. Similarly Eudragit polymers are also copolymers derived from esters of acrylic and methacrylic acid and have large number of applications in extending drug delivery. This article reviewed the role of Chitosan and Eudragit in controlled release drug formulations. Also, the article included role, property and uses of Chitosan and Eudragit and their use in different drug delivery system ...
TY - JOUR. T1 - Development of solid lipid nanoparticles for enhanced solubility of poorly soluble drugs. AU - Potta, Sriharsha Gupta. AU - Minemi, Sriharsha. AU - Nukala, Ravi Kumar. AU - Peinado, Chairmane. AU - Lamprou, Dimitrios A.. AU - Urquhart, Andrew. AU - Douroumis, D.. PY - 2010/12. Y1 - 2010/12. N2 - Cyclosporine (CyA) solid lipid nanoparticles were prepared by using a solvent free high pressure homogenization process. CyA was incorporated into SLNs that consisted of stearic acid, trilaurin or tripalmitin lipid solid cores in order to enhance drug solubility. The process was conducted by varying lipid compositions, drug initial loading and applied homogenization pressure. The processing temperatures were above the lipid melting points for all formulations. The empty and CyA loaded SLN particles made were characterized for particle size stability over six months. Atomic force microscopy (AFM) and photon correlation spectroscopy (PCS) showed particle sizes ranging from 112-177 nm for ...
The susceptibility of ethoxylated non-ionic surfactants to oxidation on exposure to air was investigated. Surfactants have a complex chemical composition and are widely used in a variety of applications for to their amphiphilic properties. Ethoxylated non-ionic surfactants are regarded by the producers to be stable at normal handling. However, ethoxylated surfactants are polyethers and as such susceptible to oxidation on exposure to air, which is theoretically discussed in literature. Hand eczema is a common occupational disease of which mom than half of the cases is considered to be caused by work with surfactants and water. Surfactants are known to cause skin irritation, but cases of allergic contact dermatitis have also been reported.. Some ethoxylated surfactants were handled at room temperature in a manner that imitated ordinary handling at work. All samples autoxidized and the structures of some of the components formed were identified with liquid chromatography (HPLC) and gas ...
Values obtained for specific surface area depend on the method of measurement. In adsorption based methods, the size of the adsorbate molecule (the probe molecule), the exposed crystallographic planes at the surface and measurement temperature all affect the obtained specific surface area.[4] For this reason, in addition to the most commonly used Brunauer-Emmett-Teller (N2-BET) adsorption method, several techniques have been developed to measure the specific surface area of particulate materials at ambient temperatures and at controllable scales, including methylene blue (MB) staining, ethylene glycol monoethyl ether (EGME) adsorption,[5] electrokinetic analysis of complex-ion adsorption[4] and a Protein Retention (PR) method.[6]. ...
Generally, although the conventional drug delivery systems, such as using only pHdependent polymers or time-dependent release systems are popular, the individuals variations of physiological conditions usually lead to premature or imperfect drug release from each of these systems. Therefore, a combination of pH- and time-dependent polymers could be more reliable for delivering drugs to the lower GI tract such as colon. To this end, electrospinning method was used as a fabrication approach for preparing electrospun nanofibers of indomethacin aimed for colon delivery. Formulations were prepared based on a 3 2 full factorial design. Independent variables were the drug:polymer ratio (with the levels of 3:5, 4.5:5 and 6:5 w/w) and Eudragit S:Eudragit RS w/w ratio (20:80, 60:40 and 100:0). The evaluated responses were drug release at pH 1.2, 6.4, 6.8 and 7.4. Combinations of Eudragit S (ES), Eudragit RS (ERS) and drug based on factorial design were loaded in 10 ml syringes. 3 Electrospinning method ...
Generally, although the conventional drug delivery systems, such as using only pHdependent polymers or time-dependent release systems are popular, the individuals variations of physiological conditions usually lead to premature or imperfect drug release from each of these systems. Therefore, a combination of pH- and time-dependent polymers could be more reliable for delivering drugs to the lower GI tract such as colon. To this end, electrospinning method was used as a fabrication approach for preparing electrospun nanofibers of indomethacin aimed for colon delivery. Formulations were prepared based on a 3 2 full factorial design. Independent variables were the drug:polymer ratio (with the levels of 3:5, 4.5:5 and 6:5 w/w) and Eudragit S:Eudragit RS w/w ratio (20:80, 60:40 and 100:0). The evaluated responses were drug release at pH 1.2, 6.4, 6.8 and 7.4. Combinations of Eudragit S (ES), Eudragit RS (ERS) and drug based on factorial design were loaded in 10 ml syringes. 3 Electrospinning method ...
TY - JOUR. T1 - Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen. AU - Löbmann, Korbinian. AU - Laitinen, Riikka. AU - Grohganz, Holger. AU - Gordon, Keith C.. AU - Strachan, Clare. AU - Rades, Thomas. PY - 2011. Y1 - 2011. N2 - One of the challenges in drug development today is that many new drug candidates are poorly water-soluble, and one of the approaches to overcome this problem is to transfer a crystalline drug into its amorphous form, thus increasing dissolution rate and apparent solubility of the compound. In this study, a coamorphous drug/drug combination between the two nonsteroidal anti-inflammatory drugs, naproxen and ¿-indomethacin, was prepared and investigated. At molar ratios of 2:1, 1:1 and 1:2, the drugs were quench cooled in order to obtain a coamorphous binary phase. Physical stability was examined at 277.15 and 298.15 K under dry conditions (phosphorus pentoxide) and analyzed with X-ray powder diffraction (XRPD). ...
CLOBETASOL PROPIONATE EMULSION (clobetasol propionate aerosol, foam) comes in different strengths and amounts. The appearance of Clobetasol Propionate Emulsion can differ based on the dosing.
Objective: Rizatriptan Benzoate is the 5H1 receptor agonist and used in treatment of migraine, cluster headache. The main objective is to develop ideal anti-migraine nasal mucoadhesive microparticles as local and systemic drug delivery system. Method: An attempt was made to formulate the nasal mucoadhesive microparticle of Rizatriptan Benzoate with excipients like mucoadhesive polymers i.e HPMC, ethyl cellulose etc., by using modified solvent evaporation method. And evaluated them for production yield, drug loading efficiency, surface morphology by SEM, drug content, particle size, In-vitro drug release studies. The release rates were studied using GRAPHPAD PRISM software. Result and discussion: The prepared microparticles of Rizatriptan Benzoateformulations were found to be satisfactory particle size i.e in the range of 36.96 to 53.28µm,mucoadhesion time of F5 found to be 370 min,drug content was found to be72.86 % to 81.80 % and drug release of the drug follow zero order kinetic model. ...
Abstract: Ritonavir, a widely prescribed anti-retroviral drug, belongs to Class II under \BCS\ and exhibit low and variable oral bioavailability due to its poor aqueous solubility. Ritonavir is practically insoluble in water and aqueous fluids. Its aqueous solubility was reported to be 2.56 mg/100 ml. As such oral absorption of ritonavir is dissolution rate limited and it requires enhancement in solubility and dissolution rate for increasing its oral bioavailability. In the case of poorly soluble drugs formulation variables greatly influence their dissolution rate and bioavailability from solid dosage forms. The objective of the present work is to study the effect of five superdisintegrants and three solubilizers on the tablet qualities and dissolution rate of ritonavir tablets to optimize the formulation of ritonavir tablets. Compressed tablets each containing 100 mg of ritonavir were prepared by conventional wet granulation method using five superdisintegrants namely Prosolve, modified ...
In the present work emphasize on Esomeprazole magnesium is formulated as delayed release tablets to provide desired effect at certain time in maintained drug concentration without any unwanted effect with patient compliance also to improve it bioavailability by decreasing its expose to gastric acid. A delayed release dosage form is designed to release the drug from the dosage form at a time other than promptly after administration. UV spectrophotometric method has been developed for the estimation of Esomeprazole in pharmaceutical formulations. Then the tablets were prepared by wet granulation method rather than direct compression because of cohesive property of the drug. Optimized core tablet then subjected for enteric coating by selected base coat polymer cellulose derivative for preventing core tablet from moisture. The coated formulations were compared with marketed sample (ESOZ) for optimization. Dissolution results of tablets with enteric coating have shown release of ...
The use of X-ray powder diffraction as a method for air monitoring was discussed. Most of the airborne dusts monitored by this method have been crystalline compounds, which indicates that they will give distinctive X-ray diffraction patterns. Primarily X-ray powder diffraction has been used for inorganic compounds. The report discussed the principle of the method including theory, qualitative anal
Ketorolac + hydroxypropylmethylcellulose is used in the treatment of .get complete information about ketorolac + hydroxypropylmethylcellulose including usage, side effects, drug interaction, expert advice along with medicines associated with ketorolac + hydroxypropylmethylcellulose at 1mg.com
Looking for online definition of Self-Emulsifying or what Self-Emulsifying stands for? Self-Emulsifying is listed in the Worlds largest and most authoritative dictionary database of abbreviations and acronyms
Global Xanthan Gum Market is expected to reach USD 987.7 million by 2020, according to a new study by Grand View Research, Inc. Growth of oil & gas industry is expected to be one of the primary factors driving xanthan gum demand over the forecast period. Increasing use of xanthan gum as an emulsion across a wide array of applications including salad dressings, toppings, relishes, sauces, non-fat milk, dairy products, baked and frozen foods coupled with growth of food & beverage industry is anticipated to augment market growth.. Oil & gas and food & beverages together accounted for over 80% of xanthan gum market in terms of volume as well as revenue in 2013. Food & beverages is anticipated to be the fastest growing application of xanthan gum over the forecast period closely followed by oil & gas. Growing population, changing lifestyle of consumers and rising number of restaurants and cafes especially in India and China coupled with increasing use of xanthan gum as a low price alternative to guar ...
China Isopropyl Myristate (IPM) for Cosmetics, Find details about China Isopropyl Myristate, Emollient from Isopropyl Myristate (IPM) for Cosmetics - Sinochem Qingdao Co., Ltd.
Mucin was extracted from the African giant snail and in combination with PEG was used to produce a copolymer matrix base, which was mixed with the model drugs using wet granulation method. The granules and tablets were evaluated according to official and unofficial requirements. Results showed best flow with Acetylsalicylic acid [ASA] and Chloroquine Phosphate [CQ] granules with Hausner ratio of 1.04-1.2, Carrs index of 4.2-17.5% and angle of repose between 19°-26°. The tablets met B. P specifications with respect to tablet weights, friability and drug content. The release profiles showed faster release of the drug with high content of PEG and a slower release with high concentration of mucin. Pegylated mucin base will find useful application in the development of a wide range of formulations ...
MORE INFO:. Active Ingredient: Finasteride.. Inactive Ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, hydroxypropyl methylcellulose, hydroxypropyl cellulose LF, titanium dioxide, magnesium stearate, talc, docusate sodium, yellow ferric oxide, and red ferric oxide.. Propecia can affect a blood test called PSA (Prostate-Specific Antigen) for the screening of prostate cancer. If you have a PSA test done, you should tell your doctor(s) that you are taking Propecia. Because Propecia decreases PSA levels, changes in PSA levels will need to be carefully evaluated by your doctor(s). Any increase in follow-up PSA levels from their lowest point should be carefully evaluated even if the test results are still within the normal range for men not taking Propecia. You should also tell your doctor if you have not been taking Propecia as prescribed because this may affect the PSA test results. For more information, talk to your doctor. ...
Excessive mechanical loading to a joint has been linked with the development of posttraumatic osteoarthritis (OA). Among the suspected links between impact trauma to a joint and associated degeneration of articular cartilage is an acute reduction in chondrocyte viability. Recently, the non-ionic surfactant poloxamer 188 (P188) has been shown to reduce by approximately 50% the percentage of non-viable chondrocytes 24 hours post injury in chondral explants exposed to 25 MPa of unconfined compression. There is a question whether these acutely saved chondrocytes will continue to degrade over time, as P188 is only thought to act by acute repair of damaged cell membranes. In order to investigate the degradation of traumatized chondrocytes in the longer term, the current study utilized TUNEL staining to document the percentage of cells suffering DNA fragmentation with and without an immediate 24 hour period of exposure of the explants to P188 surfactant. In the current study, as in the previous study ...
A new Fourier Transform-Infra Red (FT-IR) spectrometric method was developed for assaying hydrochlorothiazide (HCT) and enalapril maleate (ENM) in binary solid pharmaceutical formulations. Multivariate Partial Least Squares (PLS) method was used for calibration of derivative spectral data. Acetonitrile was used as solvent due to its spectral transparency and adequate solubility of analytes in it. A 4- levels full factorial design of binary standard solutions of HCT and ENM were prepared and used for calibration in the spectral range of 1550-1800 cm-1. Statistical parameters such as correlation coefficient(R), Standard Error of Estimation (SEE), Standard Error of Prediction (SEP), and Standard Error of Cross Validation (SECV) have been evaluated and used for selecting of optimizing of parameters. Correlation coefficients were 0.9990 and 0.9995 and Relative Standard Deviation (RSD) were 1.97% and 1.35% (n=5) for HCT and ENM, respectively. Detection limits of ENM and HCT were ...
The objective of this study was to investigate the release behaviour of propranolol hydrochloride from psyllium matrices in the presence hydrophilic polymers. The dissolution test was carried out at pH 1.2 and pH 6.8. Binary mixtures of psyllium and hydroxypropyl methylcellulose (HPMC) used showed that an increase in the percentage of HPMC in the binary mixtures caused a significant decrease in the release rate of propranolol. Psyllium-alginate matrices produced lower drug release as compared to when the alginate was the matrix former alone. When sodium carboxy methyl cellulose (NaCMC) was incorporated into the psyllium, the results showed that matrices containing the ratio of psyllium-NaCMC in the 1:1 ratio are able to slow down the drug release significantly as compared to matrices made from only psyllium or NaCMC as retardant agent suggesting that there could be a synergistic effect between psyllium and NaCMC. The double-layered tablets showed that the psyllium and HPMC in the outer shell of ...
Seek medical attention right away if any of these severe side effects occur:. Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. ...
Functionalization of metal nanoparticles with liquid crystal polymers (LCP) is attractive for the formation of supramolecular structures with unique physical properties. We discovered that the chemical linkage of a liquid crystalline thiolated cellulose ester (HPC-MTP_80) to gold nanoparticles (AuNP) leads, by control of the supramolecular structure, to a novel concept for functional materials with practical applications. At a critical concentration ratio of only 1.7 mol % HPC-MTP_80, on average, only single HPC-MTP_80 functionalized AuNP exist, forming a LC phase. Pure HPC-MTP_80 forms a cholesteric phase with a pitch in the range of visible light. The slow pitch formation enables usage as a protective sealing material. This property in combination with the temperature dependence of the pitch makes HPC-MTP_80 a perfect sensor for temperature monitoring of sensitive products like valuable pharmaceutics. Even the presence of very small amounts of functionalized AuNP in the nanocomposite suppress ...

Hydroxycut Max for Women - ProgressiveHealth.comHydroxycut Max for Women - ProgressiveHealth.com

It is used as an excipient in pharmaceutical preparations. Therefore, oleic acid serves as a solubilizing agent in Hydroxycut ...
more infohttp://www.progressivehealth.com/hydroxycut-weight-loss-supplement-for-women.htm

Synthesis, characterization and biocompatibility of cadmium sulfide nanoparticles capped with dextrin for in vivo and in vitro...Synthesis, characterization and biocompatibility of cadmium sulfide nanoparticles capped with dextrin for in vivo and in vitro...

Lederer M, Leipzig-Paganini E. Dextrin as excipient in pharmaceutical preparations. Pharmazie. 2000;55:378-9.Google Scholar. ... It is soluble in water and used as a binder in pharmaceutical products [33]. ...
more infohttps://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-015-0145-x

Patent US20030059472 - Preparation of submicron sized nanoparticles via dispersion lyophilization - Google PatentsuchePatent US20030059472 - Preparation of submicron sized nanoparticles via dispersion lyophilization - Google Patentsuche

Or the organic compound might be from the group used as adjuvants or excipients in pharmaceutical preparations and cosmetics, ... High-pressure sterilization to terminally sterilize pharmaceutical preparations and medical products. US8716451. 12. Jan. 2006 ... Microprecipitation of nanoparticulate pharmaceutical agents. US5560933 *. 29. M rz 1995. 1. Okt. 1996. Vivorx Pharmaceuticals, ... Microprecipitation of nanoparticulate pharmaceutical agents using surface active material derived from similar pharmaceutical ...
more infohttp://www.google.de/patents/US20030059472

Mussel-Inspired Polydopamine Coated Iron Oxide Nanoparticles for Biomedical ApplicationMussel-Inspired Polydopamine Coated Iron Oxide Nanoparticles for Biomedical Application

Shandong Provincal Engineering Laboratory of Novel Pharmaceutical Excipients, Sustained and Controlled Release Preparations, ...
more infohttps://www.hindawi.com/journals/jnm/2015/154592/cta/

Triage: Generic vs brand name birth controlTriage: Generic vs brand name birth control

Pharmaceutical preparations contain active ingredients combined with EXCIPIENTS or inactive ingredients.. For all - FACT - ... The funny thing is, many generic pharmaceuticals are made from the EXACT same stock at the same facility. The article is ... Additional FACT - some patients have allergic reactions to some excipients and this is just as likely to happen with the brand ... Now, some brand name pharmaceutical companies are making the generics when their patent expires, or even dropping the price of ...
more infohttps://newsblogs.chicagotribune.com/triage/2009/07/generic-vs-brand-name-birth-control.html

Application of Silver Nanoparticles for the Spectrophotometric Determination of Cefdinir and Cefepime HCl in Pharmaceutical...Application of Silver Nanoparticles for the Spectrophotometric Determination of Cefdinir and Cefepime HCl in Pharmaceutical...

Good recoveries were obtained without interference from pharmaceutical preparations excipients or urine endogenous matrix ... The proposed method was applied successfully to determination of CFD and CFP in pure drugs, pharmaceutical preparations and ... The proposed method was applied successfully to determination of CFD and CFP in pure drugs, pharmaceutical preparations and ... pharmaceutical preparations, and in urine samples. The proposed method was simple, sensitive, accurate, green and inexpensive ...
more infohttp://www.nanobe.org/Data/View/625

Patent US5639738 - Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic ... - Google PatentsPatent US5639738 - Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic ... - Google Patents

A pharmaceutical excipient suitable for topical application is included. The NSAID in the composition may be diclofenac sodium. ... or a pharmacological substance optionally together with additional conventional excipients for pharmaceutical preparations for ... Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.. Topical pharmaceutical and medical device preparations containing ... pharmaceutical combinations and formulations comprising, together with pharmaceutical excipients suitable for topical ...
more infohttp://www.google.ca/patents/US5639738

1200 USP Chemicals1200 USP Chemicals

It is considered one of the five common excipient solvents suitable for pharmaceutical preparations, including water, methanol ... Agar, Powder, NF is used in the pharmaceutical industry for many applications such as a suspending agent, surgical lubricants ... Agar, Granular, NF is used in the pharmaceutical industry for many applications such as a suspending agent, surgical lubricants ...
more infohttps://www.spectrumchemical.com/OA_HTML/1200-USP-Chemicals.jsp?minisite=10020&respid=22372

Bulk Fine Chemicals | Spectrum ChemicalBulk Fine Chemicals | Spectrum Chemical

It is considered one of the five common excipient solvents suitable for pharmaceutical preparations, including water, methanol ... Acacia, Milled Powder, NF is an excipient binder. Spectrum Chemical NF products are manufactured, packaged and stored under ... Acacia, Spray-Dried Powder, NF is an excipient binder. Spectrum Chemical NF products are manufactured, packaged and stored ...
more infohttps://www.spectrumchemical.com/OA_HTML/Chemicals_Bulk-Fine-Chemicals.jsp

Global PCR Technologies Market Research Report - Trends & Forecast to 2020 | Dec 2, 2014 - ReleaseWireGlobal PCR Technologies Market Research Report - Trends & Forecast to 2020 | Dec 2, 2014 - ReleaseWire

In addition to active ingredients, pharmaceutical excipients are also contained in pharmaceutical preparations after reasonable ... Pharmaceutical excipients refer to adjuvants and additives used for production of pharmaceuticals and compounding of ... China has launched more than 500 types of pharmaceutical excipients, far less than 1,500 types of the United States and 3,000 ... and lactose rank as the top 10 pharmaceutical excipients in China.. China Recombinant Protein Drug Industry Report, 2014-2017. ...
more infohttp://www.sbwire.com/press-releases/release-565577.htm

China Independent Clinical Laboratory Industry Research Report, 2014-2017 | Jan 20, 2015 - ReleaseWireChina Independent Clinical Laboratory Industry Research Report, 2014-2017 | Jan 20, 2015 - ReleaseWire

In addition to active ingredients, pharmaceutical excipients are also contained in pharmaceutical preparations after reasonable ... Pharmaceutical excipients refer to adjuvants and additives used for production of pharmaceuticals and compounding of ... China has launched more than 500 types of pharmaceutical excipients, far less than 1,500 types of the United States and 3,000 ... and lactose rank as the top 10 pharmaceutical excipients in China.. China Recombinant Protein Drug Industry Report, 2014-2017. ...
more infohttp://www.sbwire.com/press-releases/release-575054.htm

Gentisic acid - WikipediaGentisic acid - Wikipedia

... gentisic acid is readily oxidised and is used as an antioxidant excipient in some pharmaceutical preparations. In the ...
more infohttps://en.wikipedia.org/wiki/Gentisic_acid

Iraq Academic Scientific JournalsIraq Academic Scientific Journals

No interference was observed from common excipients present in pharmaceutical preparations. The good correlation coefficients ... Spectrophotometric determination of Phenylephrine hydrochloride and Salbutamol sulphate drugs in pharmaceutical preparations ... The suggested method was further applied for the determinations of drugs in commercial pharmaceutical preparations, which was ... in pharmaceutical dosage forms. The method is based on the diazotization reaction of metoclopramide hydrochloride (MCP) and ...
more infohttps://www.iasj.net/iasj?func=issueTOC&isId=6046&uiLanguage=en

Exhibitors | CPhI SEA | Bangkok is CallingExhibitors | CPhI SEA | Bangkok is Calling

We devote ourselves to manufacturing APIs, Fine Chemicals, Preparations intermediates, Food Additives, Pharmaceutical ... Excipients, Veterinary Drugs, and Feed additives. All companies of Guobang Group are granted with certifications such as GMP, ... Guobang Group:Guobang Pharmachem Group Co LtdZhejiang Guobang Pharmaceutical Co LtdShandong Guobang Pharmaceutical Co ... Enjoying large market share, having an extensive glass containers range in pharmaceutical, food and beverage categories coupled ...
more infohttps://www.cphi.com/sea/exhibitors/G

Hypromellose | definition of hypromellose by Medical dictionaryHypromellose | definition of hypromellose by Medical dictionary

... and excipient in pharmaceutical preparations, and applied topically to the conjunctiva to protect and lubricate the cornea. ... Sunhere Pharmaceutical Excipients is a Chinese member of International Pharmaceutical Excipient Confederation (IPEC), mainly ... and excipient in pharmaceutical preparations, and applied topically to the conjunctiva to protect and lubricate the cornea. ... hypromellose and other 18 types of new-type pharmaceutical excipients with the capacity of 10,000 tons.. China Pharmaceutical ...
more infohttps://medical-dictionary.thefreedictionary.com/hypromellose

Patent US6495177 - Orally dissolvable nutritional supplement - Google PatentsPatent US6495177 - Orally dissolvable nutritional supplement - Google Patents

... in the prior art has included simethicone either as a pharmaceutical excipient in topical pharmaceutical preparations or as an ... Chewable pharmaceutical tablets. US5869084 *. Jun 7, 1995. Feb 9, 1999. K-V Pharmaceuticals Co.. Multi-vitamin and mineral ... The inventors believe that simethicone has not previously been used as an excipient in orally administrable preparations (e.g. ... Simethicone has also been used as a pharmaceutical excipient in topical formulations such as ointments and skin protectants. ...
more infohttp://www.google.com/patents/US6495177?dq=7,546,338

Berkongsi Pendapat Pemakanan Sihat & Daging Segar: FACTS / ORIGIN of E-CODE IN FOODBerkongsi Pendapat Pemakanan Sihat & Daging Segar: FACTS / ORIGIN of E-CODE IN FOOD

It is also present in excipients in pharmaceutical preparations, particularly vitamin and mineral supplements Hydrolyzed Plant ...
more infohttp://dagingsegar.blogspot.com/2008/05/factsgroup-of-e-code-in-food.html

Pharmacopoeia of the Peoples Republic of China - WikipediaPharmacopoeia of the People's Republic of China - Wikipedia

... biochemical preparations, Radiopharmaceuticals and excipients for pharmaceutical use; Volume III contains biological products ... "compendium of almost all traditional Chinese medicines and most western medicines and preparations. Information is given for ... single ingredient of Chinese crude drug preparations etc.; Volume II deals with monographs of chemical drugs, antibiotics, ...
more infohttps://en.wikipedia.org/wiki/Pharmacopoeia_of_the_People's_Republic_of_China

DE3931041C2 -   Esters of Thienylcarbonsäuren with aminoalcohols, their quaternization products, processes for their...DE3931041C2 - Esters of Thienylcarbonsäuren with aminoalcohols, their quaternization products, processes for their...

... or excipients are processed to conventional pharmaceutical preparations,. B. zu Inhalationslösungen, Suspensionen in ... Teva Branded Pharmaceutical Prod R & D Inc. An inhalable medicament PT2607351T (en) * 2011-12-22. 2017-05-26. Cerbios-Pharma S ... Ono Pharmaceutical Co., Ltd.. Tropan compound PT1881980E (en) 2005-05-02. 2012-12-06. Boehringer Ingelheim Int. Novel ... Quinuclidines, their pharmaceutical use and process for their preparation US5624947A (en) 1997-04-29. Phenyl derivatives useful ...
more infohttps://patents.google.com/patent/DE3931041C2/en

Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using...Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using...

The developed method was successfully applied for the determination of these drugs in pharmaceutical preparations. Excipients ... 3.2.3. Analysis Pharmaceutical Preparations. The developed and validated method was applied to analyses of the drug substances ... LVD, ZVD, and their pharmaceutical preparations Zeffix (containing 100 mg of LVD per tablet) and Retrovir (containing 250 mg of ... Extractive Spectrophotometric Method for the Determination of Lamivudine and Zidovudine in Pharmaceutical Preparations Using ...
more infohttps://www.hindawi.com/journals/jchem/2013/484389/

Quantification of Ethanol Content in Traditional Herbal Cough Syrups | Pharmacognosy JournalQuantification of Ethanol Content in Traditional Herbal Cough Syrups | Pharmacognosy Journal

Introduction: The use of alcohol as an excipient in pharmaceutical preparations raises safety concerns, especially when used in ... Conclusion: More rigorous regulation on alcohol content in herbal preparations, and disclosure of alcohol content in product ...
more infohttp://phcogj.com/article/413

US5747248A - Discontinuous probe design using hybritope mapping 
        - Google PatentsUS5747248A - Discontinuous probe design using hybritope mapping - Google Patents

... pharmaceutical preparations may contain suitable excipients and auxiliaries which facilitate processing of the active compounds ... The compounds may be administered as pharmaceutical compositions in combination with a pharmaceutically acceptable excipient. ... A thorough discussion of pharmaceutically acceptable excipients is available in Remingtons Pharmaceutical Sciences (Mack Pub. ... The antisense compositions of the present invention may be prepared for pharmaceutical administration. Injection preparations ...
more infohttps://patents.google.com/patent/US5747248

Small molecule inhibitors of Lck SH2 domain binding - Patent # 8476273 - PatentGeniusSmall molecule inhibitors of Lck SH2 domain binding - Patent # 8476273 - PatentGenius

Examples of potential formulations and preparations are contained, forexample, in the Handbook of Pharmaceutical Excipients, ... American Pharmaceutical Association (current edition); Pharmaceutical Dosage Forms: Tablets (Lieberman, Lachman and Schwartz, ... Other preparations are also possible.. Suppositories for rectal administration of the compounds of the present invention can be ... Such dosage forms can also contain suitable inertdiluents known in the art such as water and suitable excipients known in the ...
more infohttp://www.patentgenius.com/patent/8476273.html
  • More rigorous regulation on alcohol content in herbal preparations, and disclosure of alcohol content in product packagings should be enforced. (phcogj.com)
  • Pharmaceutical manufacturing is a global industry, and the trend towards harmonization of pharmaceutical standards is reflected in this edition in greater emphasis being placed on data gathered from around the world. (abebooks.com)
  • Guobang Pharmachem Group is a non-bounded Group specialized in Pharmaceutical and Chemical Industries, with manufacturing sites located in Zhejiang Xinchang Industrial Area, Hangzhou Gulf Shangyu Industrial Zone, Shnadong Weifang National Economic and Technology Development Zone, etc, and R&D, Logistics and Management Organizations in Shangyu, Shaoxing and Hangzhou. (cphi.com)
  • The Handbook of Pharmaceutical Excipients collects, in a systematic and unified manner, essential data on the physical and chemical properties of excipients. (abebooks.com)
  • Information has been assembled from a variety of sources, including the primary literature and excipients manufacturers. (abebooks.com)