AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
PericardiumGlutaralPericardial EffusionPericardiectomyBioprosthesisPericarditis, ConstrictivePericarditisCardiac TamponadeFixativesHeart NeoplasmsPenile ImplantationHeart Valve ProsthesisVenae CavaeMediastinal CystSuture TechniquesPneumopericardiumTissue FixationHeart InjuriesPericardiocentesisCardiac Surgical ProceduresScleral DiseasesFascia LataAortic ValveDogsCattleCalcinosisHeart SeptumSternotomyPleuraPericardial Window TechniquesHeart AneurysmGlaucoma Drainage ImplantsSubcutaneous TissueFreeze DryingBiocompatible MaterialsAntigens, HeterophileMyosarcomaFatal OutcomeEchocardiographyTomography, X-Ray ComputedMitral ValveReoperationTricuspid ValvePolyethylene TerephthalatesVentricular FunctionAbortion, SepticTensile StrengthComplianceHeart Valve Prosthesis ImplantationHeart ValvesMesotheliomaHeart Valve DiseasesAortic Valve InsufficiencyFistulaProstheses and ImplantsPericarditis, TuberculousAtrial Function, RightHeart VentriclesTeleradiologyHeart Defects, CongenitalHerniaChordae TendineaeSternumCardiac VolumeTreatment OutcomeLipomaHeartHemothoraxSurgical FlapsThoracotomyTissue PreservationThoraxDiastoleHeart DiseasesHemangiosarcomaProsthesis ImplantationVentricular Function, RightTissue Adhesives
Pericardium
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
Glutaral
One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Pericardial Effusion
Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.
Pericardiectomy
Surgical excision (total or partial) of a portion of the pericardium. Pericardiotomy refers to incision of the pericardium.
Bioprosthesis
Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.
Pericarditis, Constrictive
Inflammation of the PERICARDIUM that is characterized by the fibrous scarring and adhesion of both serous layers, the VISCERAL PERICARDIUM and the PARIETAL PERICARDIUM leading to the loss of pericardial cavity. The thickened pericardium severely restricts cardiac filling. Clinical signs include FATIGUE, muscle wasting, and WEIGHT LOSS.
Pericarditis
Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.
Cardiac Tamponade
Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.
Fixatives
Agents employed in the preparation of histologic or pathologic specimens for the purpose of maintaining the existing form and structure of all of the constituent elements. Great numbers of different agents are used; some are also decalcifying and hardening agents. They must quickly kill and coagulate living tissue.
Heart Neoplasms
Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
Penile Implantation
Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.
Heart Valve Prosthesis
A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.
Venae Cavae
The inferior and superior venae cavae.
Mediastinal Cyst
Cysts of one of the parts of the mediastinum: the superior part, containing the trachea, esophagus, thoracic duct and thymus organs; the inferior middle part, containing the pericardium; the inferior anterior part containing some lymph nodes; and the inferior posterior part, containing the thoracic duct and esophagus.
Suture Techniques
Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).
Pneumopericardium
Presence of air or gas in the space between the heart and the PERICARDIUM. The degree of respiratory distress depends on the amount of trapped air and circulation blocked in the systemic and pulmonary veins.
Tissue Fixation
The technique of using FIXATIVES in the preparation of cytologic, histologic, or pathologic specimens for the purpose of maintaining the existing form and structure of all the constituent elements.
Heart Injuries
General or unspecified injuries to the heart.
Pericardiocentesis
Puncture and aspiration of fluid from the PERICARDIUM.
Cardiac Surgical Procedures
Surgery performed on the heart.
Scleral Diseases
General disorders of the sclera or white of the eye. They may include anatomic, embryologic, degenerative, or pigmentation defects.
Fascia Lata
CONNECTIVE TISSUE of the anterior compartment of the THIGH that has its origins on the anterior aspect of the iliac crest and anterior superior iliac spine, and its insertion point on the iliotibial tract. It plays a role in medial rotation of the THIGH, steadying the trunk, and in KNEE extension.
Aortic Valve
The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.
Dogs
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Cattle
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Calcinosis
Pathologic deposition of calcium salts in tissues.
Heart Septum
This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.
Sternotomy
Making an incision in the STERNUM.
Pleura
The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.
Pericardial Window Techniques
Surgical construction of an opening or window in the pericardium. It is often called subxiphoid pericardial window technique.
Heart Aneurysm
A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.
Glaucoma Drainage Implants
Devices, usually incorporating unidirectional valves, which are surgically inserted in the sclera to maintain normal intraocular pressure.
Subcutaneous Tissue
Loose connective tissue lying under the DERMIS, which binds SKIN loosely to subjacent tissues. It may contain a pad of ADIPOCYTES, which vary in number according to the area of the body and vary in size according to the nutritional state.
Freeze Drying
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
Biocompatible Materials
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
Antigens, Heterophile
Antigens stimulating the formation of, or combining with heterophile antibodies. They are cross-reacting antigens found in phylogenetically unrelated species.
Myosarcoma
A general term for a malignant neoplasm derived from muscular tissue. (Stedman, 25th ed)
Fatal Outcome
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Echocardiography
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
Tomography, X-Ray Computed
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Mitral Valve
The valve between the left atrium and left ventricle of the heart.
Reoperation
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Tricuspid Valve
The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.
Polyethylene Terephthalates
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
Ventricular Function
The hemodynamic and electrophysiological action of the HEART VENTRICLES.
Abortion, Septic
Any type of abortion, induced or spontaneous, that is associated with infection of the UTERUS and its appendages. It is characterized by FEVER, uterine tenderness, and foul discharge.
Tensile Strength
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
Compliance
Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
Heart Valve Prosthesis Implantation
Surgical insertion of synthetic material to repair injured or diseased heart valves.
Heart Valves
Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.
Mesothelioma
A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Heart Valve Diseases
Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
Aortic Valve Insufficiency
Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
Fistula
Abnormal communication most commonly seen between two internal organs, or between an internal organ and the surface of the body.
Prostheses and Implants
Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.
Pericarditis, Tuberculous
INFLAMMATION of the sac surrounding the heart (PERICARDIUM) due to MYCOBACTERIUM TUBERCULOSIS infection. Pericarditis can lead to swelling (PERICARDIAL EFFUSION), compression of the heart (CARDIAC TAMPONADE), and preventing normal beating of the heart.
Atrial Function, Right
The hemodynamic and electrophysiological action of the RIGHT ATRIUM.
Heart Ventricles
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Teleradiology
The electronic transmission of radiological images from one location to another for the purposes of interpretation and/or consultation. Users in different locations may simultaneously view images with greater access to secondary consultations and improved continuing education. (From American College of Radiology, ACR Standard for Teleradiology, 1994, p3)
Heart Defects, Congenital
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.
Hernia
Protrusion of tissue, structure, or part of an organ through the bone, muscular tissue, or the membrane by which it is normally contained. Hernia may involve tissues such as the ABDOMINAL WALL or the respiratory DIAPHRAGM. Hernias may be internal, external, congenital, or acquired.
Chordae Tendineae
The tendinous cords that connect each cusp of the two atrioventricular HEART VALVES to appropriate PAPILLARY MUSCLES in the HEART VENTRICLES, preventing the valves from reversing themselves when the ventricles contract.
Sternum
A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.
Cardiac Volume
The volume of the HEART, usually relating to the volume of BLOOD contained within it at various periods of the cardiac cycle. The amount of blood ejected from a ventricle at each beat is STROKE VOLUME.
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Lipoma
A benign tumor composed of fat cells (ADIPOCYTES). It can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
Heart
The hollow, muscular organ that maintains the circulation of the blood.
Hemothorax
Hemorrhage within the pleural cavity.
Surgical Flaps
Tongues of skin and subcutaneous tissue, sometimes including muscle, cut away from the underlying parts but often still attached at one end. They retain their own microvasculature which is also transferred to the new site. They are often used in plastic surgery for filling a defect in a neighboring region.
Thoracotomy
Surgical incision into the chest wall.
Tissue Preservation
The process by which a tissue or aggregate of cells is kept alive outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Thorax
The upper part of the trunk between the NECK and the ABDOMEN. It contains the chief organs of the circulatory and respiratory systems. (From Stedman, 25th ed)
Diastole
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities.
Hemangiosarcoma
A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)
Prosthesis Implantation
Surgical insertion of a prosthesis.
Ventricular Function, Right
The hemodynamic and electrophysiological action of the right HEART VENTRICLE.
Tissue Adhesives
Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.

Coronary vasodilator effects of BNP: mechanisms of action in coronary conductance and resistance arteries. (1/1602)

Brain natriuretic peptide (BNP), a hormone secreted predominantly in ventricular myocytes, may influence coronary vascular tone. We studied the coronary vasodilatory response to BNP under physiological conditions and after preconstriction with endothelin-1 (ET-1) in anesthetized pigs. Average peak-flow velocity (APV) was measured using intracoronary Doppler, and cross-sectional area (CSA) was measured using intravascular ultrasound. Coronary blood flow (CBF) was calculated. Intracoronary BNP induced dose-dependent increases in CSA, APV, and CBF similar in magnitude to those induced by nitroglycerin (NTG). The magnitude of BNP-induced vasodilation was accentuated after preconstriction with ET-1. Pretreatment with either the nitric oxide synthase inhibitor Nomega-nitro-L-arginine methyl ester or the cyclooxygenase inhibitor indomethacin attenuated the coronary vasodilator effect of BNP in resistance arteries without influencing epicardial vasodilation. Pretreatment with the ATP-sensitive potassium-channel blocker glibenclamide enhanced epicardial vasodilation in response to BNP. We conclude that BNP exerts coronary vasodilator effects, predominantly in epicardial conductance vessels. An accentuated vasodilatory response to BNP occurs in ET-1-preconstricted arteries. BNP-induced vasodilation in coronary resistance arteries may be partially mediated via nitric oxide and/or prostaglandin release.  (+info)

Regional electrophysiological effects of hypokalaemia, hypomagnesaemia and hyponatraemia in isolated rabbit hearts in normal and ischaemic conditions. (2/1602)

OBJECTIVE: The aims of this study were to establish an isolated working heart model for electrophysiological recordings from the epicardium and endocardium and to examine regional effects of changes in ion concentrations in normal and ischaemic conditions. METHODS: Monophasic action potential duration (MAPD90), effective refractory period (ERP) and conduction delay were measured simultaneously in the epicardium and endocardium of rabbit hearts paced at 3.3 Hz, subjected to 30 min of regional ischaemia and 15 min of reperfusion. The hearts were exposed before and throughout ischaemia and reperfusion to hypokalaemia (K+ = 2 mM), hypomagnesaemia (Mg2+ = 0.5 mM) or hyponatraemia (Na+ = 110 mM). RESULTS: In the control hearts, no regional electrophysiological differences were seen before ischaemia, but ischaemia-induced MAPD90 shortening and postrepolarisation refractoriness were greater in the epicardium than in the endocardium and conduction delay increased only in the epicardium. Hypokalaemia shortened ERP in the epicardium (but not endocardium) and increased conduction delay in all areas before ischaemia, but it had no effects during ischaemia. During reperfusion hypokalaemia increased the incidence of recurrent tachyarrhythmias. Hypomagnesaemia had no effect before ischaemia, increased epicardial (but not endocardial) MAPD90 shortening during ischaemia, although it had no pro-arrhythmic action. Hyponatraemia increased conduction delay in all areas before ischaemia and produced asystole or severe bradycardia in all hearts. During ischaemia, hyponatraemia decreased ERP shortening and inducibility of arrhythmias in the epicardium (but not endocardium). CONCLUSIONS: We conclude that the more pronounced effect of ischaemia upon the epicardium than the endocardium can be explained by the contact of the endocardium with intracavitary perfusate. We also conclude that changes in ion concentrations may have differential regional electrical effects in normal or ischaemic conditions.  (+info)

Abnormal flow-mediated epicardial vasomotion in human coronary arteries is improved by angiotensin-converting enzyme inhibition: a potential role of bradykinin. (3/1602)

OBJECTIVES: This study was performed to determine whether angiotensin converting enzyme (ACE) inhibition improves endothelium-dependent flow-mediated vasodilation in patients with atherosclerosis or its risk factors and whether this is mediated by enhanced bradykinin activity. BACKGROUND: Abnormal coronary vasomotion due to endothelial dysfunction contributes to myocardial ischemia in patients with atherosclerosis, and its reversal may have an antiischemic action. Previous studies have shown that ACE inhibition improves coronary endothelial responses to acetylcholine, but whether this is accompanied by improved responses to shear stress remains unknown. METHODS: In 19 patients with mild atherosclerosis, metabolic vasodilation was assessed during cardiac pacing. Pacing was repeated during separate intracoronary infusions of low-dose bradykinin (BK) and enalaprilat. Endothelium-dependent and -independent vasodilation was estimated with intracoronary BK and sodium nitroprusside respectively. RESULTS: Enalaprilat did not alter either resting coronary vascular tone or dilation with sodium nitroprusside, but potentiated BK-mediated dilation. Epicardial segments that constricted abnormally with pacing (-5+/-1%) dilated (3+/-2%) with pacing in the presence of enalaprilat (p = 0.002). Similarly, BK at a concentration (62.5 ng/min) that did not alter resting diameter in the constricting segments also improved the abnormal response to a 6+/-1% dilation (p < 0.001). Cardiac pacing-induced reduction in coronary vascular resistance of 27+/-4% (p < 0.001) remained unchanged after enalaprilat. CONCLUSIONS: Thus ACE inhibition: A) selectively improved endothelium-dependent but not-independent dilation, and B) abolished abnormal flow-mediated epicardial vasomotion in patients with endothelial dysfunction, in part, by increasing endogenous BK activity.  (+info)

Bulbus arteriosus of the antarctic teleosts. I. The white-blooded Chionodraco hamatus. (4/1602)

The bulbus arteriosus of teleost fish is a thick-walled chamber that extends between the single ventricle and the ventral aorta. The functional importance of the bulbus resides in the fact that it maintains a steady blood flow into the gill system through heart contraction. Despite of this, a thorough study of the structure of the bulbus in teleost fish is still lacking. We have undertaken a morphologic study of the bulbus arteriosus in the stenothermal teleosts of the Antarctic sea. The structural organization of the bulbus arteriosus of the icefish Chionodraco hamatus has been studied here by conventional light, scanning, and transmission electron microscopy. The inner surface of the bulbus shows a festooned appearance due to the presence of longitudinal, unbranched ridges that extend between the ventricle and the arterial trunk. The wall of the bulbus is divided into endocardial, subendocardial, middle, and external layers. Endocardial cells show a large number of moderately-dense bodies. The endocardium invaginates into the subendocardium forming solid epithelial cords that contain numerous secretory vacuoles. Cells in the subendocardium group into small domains, have some of the morphological characteristics of smooth muscle cells, and appear enmeshed in a three-dimensional network of matrix filaments. Cells in the middle layer are typical smooth muscle cells. They appear arranged into layers and are surrounded by a filamentous meshwork that excludes collagen fibers. Orientation of this meshwork occurs in the vicinity of the smooth muscle cells. Elastin fibers are never observed. The external layer is formed by wavy collagen bundles and fibroblast-like cells. This layer lacks blood vessels and nerve fibers. The endocardium and the endocardium-derived cords are secretory epithelia that may be involved in the formation ofmucins or glycosaminoglycans. These mucins may have a protecting effect on the endocardium. The subendocardium and the middle layer appear to be formed by the same cell type, smooth muscle, with a gradient of differentiation from the secretory (subendocardium) to the contractile (middle layer) phenotype. Despite the absence of elastin fibers, the filamentous matrix could maintain the elastic properties of the bulbus wall. Smooth muscle cells appear to be actively involved in bulbus wall dynamics. The restriction of collagen to the external layer suggests that it may control wall dilatation and bulbus compliance. When comparison was possible, structural differences between C. hamatus and temperate teleosts seemed to be not species-related, but of phenotypic adaptative significance. This is remarkable since Antarctic fishes have lived isolated in freezing waters for the last two million years.  (+info)

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. (5/1602)

The Wilms' Tumour gene WT1 has important functions during development. Knock-out mice were shown to have defects in the urogenital system and to die at embryonic day E13.5, probably due to heart failure. Using a lacZ reporter gene inserted into a YAC construct, we demonstrate that WT1 is expressed in the early proepicardium, the epicardium and the subepicardial mesenchymal cells (SEMC). Lack of WT1 leads to severe defects in the epicardial layer and a concomitant absence of SEMCs, which explains the pericardial bleeding and subsequent embryonic death observed in Wt1 null embryos. We further show that a human-derived WT1 YAC construct is able to completely rescue heart defects, but only partially rescues defects in the urogenital system. Analysis of the observed hypoplastic kidneys demonstrate a continuous requirement for WT1 during nephrogenesis, in particular, in the formation of mature glomeruli. Finally, we show that the development of adrenal glands is also severely affected in partially rescued embryos. These data demonstrate a variety of new functions for WT1 and suggest a general requirement for this protein in the formation of organs derived from the intermediate mesoderm.  (+info)

Correlation of ventricular mechanosensory neurite activity with myocardial sensory field deformation. (6/1602)

The mechanosensory activity generated by ventricular epicardial sensory neurites associated with afferent axons in thoracic sympathetic nerves was correlated with sensory field deformation (long axis, short axis, and transmural dimension changes), regional intramyocardial pressure, and ventricular chamber pressure in anesthetized dogs. Ventricular mechanosensory neurites generated activity that correlated best with strain developed along either the long or short axis of their epicardial sensory fields in most instances. Activity did not correlate normally to local wall thickness or to regional wall or chamber pressure development in most cases. During premature ventricular contractions, the activity generated by these sensory neurites correlated best with maximum strain developed along at least one sensory field epicardial vector. Identified sensory neurites were also activated by local application of the chemical bradykinin (10 microM) or by local ischemia. These data indicate that the activity generated by most ischemia-sensitive ventricular epicardial sensory neurites associated with afferent axons in sympathetic nerves is dependent on not only their local chemical milieu but on local mechanical deformation along at least one epicardial vector of their sensory fields.  (+info)

Transient outward current, Ito1, is altered in cardiac memory. (7/1602)

BACKGROUND: Cardiac memory refers to an altered T-wave morphology induced by ventricular pacing or arrhythmias that persist for variable intervals after resumption of sinus rhythm. METHODS AND RESULTS: We induced long-term cardiac memory (LTM) in conscious dogs by pacing the ventricles at 120 bpm for 3 weeks. ECGs were recorded daily for 1 hour, during which time pacing was discontinued. At terminal study, the heart was removed and the electrophysiology of left ventricular epicardial myocytes was investigated. Control (C) and LTM ECG did not differ, except for T-wave amplitude, which decreased from 0.12+/-0.18 to -0.34+/-0.21 mV (+/-SEM, P<0.05), and T-wave vector, which shifted from -37+/-12 degrees to -143+/-4 degrees (P<0.05). Epicardial action potentials revealed loss of the notch and lengthening of duration at 20 days (both P<0.05). Calcium-insensitive transient outward current (Ito) was investigated by whole-cell patch clamp. No difference in capacitance was seen in C and LTM myocytes. Ito activated on membrane depolarization to -25+/-1 mV in C and -7+/-1 mV (P<0.05) in LTM myocytes, indicating a positive voltage shift of activation. Ito density was reduced in LTM myocytes, and a decreased mRNA level for Kv4.3 was observed. Recovery of Ito from inactivation was significantly prolonged: it was 531+/-80 ms (n=10) in LTM and 27+/-6 ms (n=9) in C (P<0.05) at -65 mV. CONCLUSIONS: Ito changes are associated with and can provide at least a partial explanation for action-potential and T-wave changes occurring with LTM.  (+info)

A role for serum response factor in coronary smooth muscle differentiation from proepicardial cells. (8/1602)

Coronary artery smooth muscle (SM) cells originate from proepicardial cells that migrate over the surface of the heart, undergo epithelial to mesenchymal transformation and invade the subepicardial and cardiac matrix. Prior to contact with the heart, proepicardial cells exhibit no expression of smooth muscle markers including SMalphaactin, SM22alpha, calponin, SMgammaactin or SM-myosin heavy chain detectable by RT-PCR or by immunostaining. To identify factors required for coronary smooth muscle differentiation, we excised proepicardial cells from Hamburger-Hamilton stage-17 quail embryos and examined them ex vivo. Proepicardial cells initially formed an epithelial colony that was uniformly positive for cytokeratin, an epicardial marker. Transcripts for flk-1, Nkx 2.5, GATA4 or smooth muscle markers were undetectable, indicating an absence of endothelial, myocardial or preformed smooth muscle cells. By 24 hours, cytokeratin-positive cells became SMalphaactin-positive. Moreover, serum response factor, undetectable in freshly isolated proepicardial cells, became strongly expressed in virtually all epicardial cells. By 72 hours, a subset of epicardial cells exhibited a rearrangement of cytoskeletal actin, focal adhesion formation and acquisition of a motile phenotype. Coordinately with mesenchymal transformation, calponin, SM22alpha and SMgammaactin became expressed. By 5-10 days, SM-myosin heavy chain mRNA was found, by which time nearly all cells had become mesenchymal. RT-PCR showed that large increases in serum response factor expression coincide with smooth muscle differentiation in vitro. Two different dominant-negative serum response factor constructs prevented the appearance of calponin-, SM22alpha- and SMgammaactin-positive cells. By contrast, dominant-negative serum response factor did not block mesenchymal transformation nor significantly reduce the number of cytokeratin-positive cells. These results indicate that the stepwise differentiation of coronary smooth muscle cells from proepicardial cells requires transcriptionally active serum response factor.  (+info)

Pericardial Adipose Tissue Volume Is Independently Associated With Human Immunodeficiency Virus Status and Prior Use of...
Increased pericardial adipose tissue is associated with higher risk of cardiovascular disease. We aimed to determine whether human immunodeficiency virus (HIV) status was independently associated with larger pericardial adipose tissue volume and to explore possible HIV-specific risk factors. Persons with HIV (PWH) were recruited from the Copenhagen Comorbidity in HIV Infection (COCOMO) Study and matched 1:1 on age and sex to uninfected controls. Pericardial adipose tissue volume was measured using cardiac computed tomography. A total of 587 PWH and 587 controls were included. Median age was 52 years, and 88% were male. Human immunodeficiency virus status was independently associated with 17 mL (95% confidence interval [CI], 10-23; P < .001) larger pericardial adipose tissue volume. Larger pericardial adipose tissue volume was associated with low CD4+ nadir and prior use of stavudine, didanosine, and indinavir. Among PWH without thymidine analogue or didanosine exposure, time since initiating ...
https://accounts.public.ce.basespace.illumina.com/b/search/article.nb?id=32027374
JDB | Free Full-Text | Transcriptional Control of Cell Lineage Development in Epicardium-Derived CellsJDB | Free Full-Text | Transcriptional Control of Cell Lineage Development in Epicardium-Derived Cells
Epicardial derivatives, including vascular smooth muscle cells and cardiac fibroblasts, are crucial for proper development of the coronary vasculature and cardiac fibrous matrix, both of which support myocardial integrity and function in the normal heart. Epicardial formation, epithelial-to-mesenchymal transition (EMT), and epicardium-derived cell (EPDC) differentiation are precisely regulated by complex interactions among signaling molecules and transcription factors. Here we review the roles of critical transcription factors that are required for specific aspects of epicardial development, EMT, and EPDC lineage specification in development and disease. Epicardial cells and subepicardial EPDCs express transcription factors including Wt1, Tcf21, Tbx18, and Nfatc1. As EPDCs invade the myocardium, epicardial progenitor transcription factors such as Wt1 are downregulated. EPDC differentiation into SMC and fibroblast lineages is precisely regulated by a complex network of transcription factors, including
http://www.mdpi.com/2221-3759/1/2/92
Extensibility of autologous pericardium roll conduit in non-confluent pulmonary artery: a case report | Journal of...Extensibility of autologous pericardium roll conduit in non-confluent pulmonary artery: a case report | Journal of...
There is great discussion about non-confluent pulmonary artery (PA) reconstruction, and several materials have been used. Autologous pericardium is considered feasible for infectious resistance, autoimmune response, extensibility, and growth potential. The patient was born at 39 weeks (body mass = 2550 g). He was diagnosed with tetralogy of Fallot, pulmonary atresia, non-confluent PA, and bilateral patent ductus arteriosus. Right and left Blalock-Taussig shunts with patent ductus arteriosus ligations were placed on day 27 and 3 months, respectively. At 19 months (8.8 kg), definitive repair was performed with tricuspid valved conduit concurrent with PA reconstruction using an autologous pericardium roll conduit. The autologous pericardium was treated with glutaraldehyde (autologous pericardium fixed with 0.4% glutaraldehyde for 7 min and rolled as conduit - 12 mm in diameter and 30 mm in length). Following an incision on the visceral side of the PAs before the 1st branch, the autologous pericardial roll
https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-019-0913-z
Epicardium-Derived Cardiac Mesenchymal Stem Cells: Expanding the Outer Limit of Heart Repair | Circulation ResearchEpicardium-Derived Cardiac Mesenchymal Stem Cells: Expanding the Outer Limit of Heart Repair | Circulation Research
The epicardium is derived from the proepicardial organ, a source of multipotent progenitor cells. Epicardium contribution to the developing coronary vasculature and to cardiac interstitial cells has been established. Studies over the past several years have suggested that epicardium-derived cells can adopt cardiomyocyte and vascular smooth muscle fates and can contribute to cardiac repair when activated by injury.1,2 Recently, Chong et al3 have provided a detailed characterization of a population of epicardium-derived multipotent cardiac progenitor cells (cCFU-Fs). These cells, which do not arise from the bone marrow, neural crest, or myocardium, resemble mesenchymal stem cells (MSCs) and may participate in cardiac development, homeostasis, and repair.3. During early cardiac development, cells derived from the proepicardial organ (a cluster of cells located dorsal and adjacent to the looped heart tube) migrate over the myocardium to form the epicardium. Subsequently, epicardium-derived ...
http://circres.ahajournals.org/content/110/7/904.long
Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease<...
TY - JOUR. T1 - Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease. AU - Iacobellis, Gianluca. AU - Pistilli, Daniela. AU - Gucciardo, Marco. AU - Leonetti, Frida. AU - Miraldi, Fabio. AU - Brancaccio, Gianluca. AU - Gallo, Pietro. AU - Tiziana Di Gioia, Cira Rosaria. PY - 2005/3/21. Y1 - 2005/3/21. N2 - Background: Intra-peritoneal adipose tissue is recognized as a predictor of metabolic syndrome and may contribute to the risk for cardiovascular disease by the production of adipocytokines, including adiponectin. Nevertheless, there is no knowledge on whether other visceral depots of adipose tissue, including the epicardial fat, have any metabolically active role, including production of adiponectin. Aim of the study: We sought to evaluate adiponectin protein expression in epicardial adipose tissue in vivo both in patients with severe coronary artery disease (CAD) and in subjects without CAD. Methods: Twenty-two patients were ...
https://miami.pure.elsevier.com/en/publications/adiponectin-expression-in-human-epicardial-adipose-tissue-in-vivo
Braz J Cardiovasc Surg - The Relationship Between Epicardial Adipose Tissue Thickness and Presence of Left...Braz J Cardiovasc Surg - The Relationship Between Epicardial Adipose Tissue Thickness and Presence of Left...
1. Stollerman GH. Rheumatic fever. Lancet. 1997;349(9056):935-42. doi:10.1016/S0140-6736(96)06364-7.. 2. Fleming HA, Bailey SM. Mitral valve disease, systemic embolism and anticoagulants. Postgrad Med J. 1971;47(551):599-604. doi:10.1136/pgmj.47.551.599. [MedLine]. 3. Iacobellis G, Corradi D, Sharma AM. Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart. Nat Clin Pract Cardiovasc Med. 2005;2(10):536-43. doi:10.1038/ncpcardio0319.. 4. Rabkin SW. Epicardial fat: properties, function and relationship to obesity. Obes Rev. 2007;8(3):253-61. doi:10.1111/j.1467-789X.2006.00293.x.. 5. Sacks HS, Fain JN. Human epicardial adipose tissue: a review. Am Heart J. 2007;153(6):907-17. doi:10.1016/j.ahj.2007.03.019.. 6. Seo JA, Kim BG, Cho H, Kim HS, Park J, Baik SH, et al. The cutoff values of visceral fat area and waist circumference for identifying subjects at risk for metabolic syndrome in elderly Korean: Ansan geriatric (AGE) cohort study. BMC Public Health. ...
http://rbccv.org.br/article/3499/en-US/the-relationship-between-epicardial-adipose-tissue-thickness-and-presence-of-left-atrial-thrombus-in-mitral-stenosis-patients
Polytetrafluoroethylene patch versus autologous pericardial patch for right ventricular outflow tract reconstruction :Sachin...Polytetrafluoroethylene patch versus autologous pericardial patch for right ventricular outflow tract reconstruction :Sachin...
Autologous pericardium either fixed or unfixed is harvested during cardiovascular procedures and has been used in the surgical reconstruction of many different areas. Using autologous pericardium as a patch material has multiple advantages such as ready availability, conformability, nonporosity, and lack of bleeding through needle holes. It may also be less likely to cause thrombosis or hemolysis. The unfixed autologous pericardium is a low-cost biomaterial that is free of donor-derived pathogens, does not provoke an immune response, and is easy to access. However, it has poor handling characteristics,[6] and the clinical use of fresh autologous pericardium in cardiovascular surgery is limited because of uncertain factors such as the onset of tissue shrinkage or stretching several years after implantation. The implants may become fibrotic and retracted, exhibiting progressive thinning with dilatation and aneurysm.[7] Retraction and fibrosis were observed when fresh pericardium was used as a ...
https://www.j-pcs.org/printarticle.asp?issn=2395-5414
Relationship of epicardial adipose tissue with atrial dimensions and diastolic function in morbidly obese subjects<...
TY - JOUR. T1 - Relationship of epicardial adipose tissue with atrial dimensions and diastolic function in morbidly obese subjects. AU - Iacobellis, Gianluca. AU - Leonetti, Frida. AU - Singh, Navneet. AU - M Sharma, Arya. PY - 2007/2/7. Y1 - 2007/2/7. N2 - Obesity is associated with atrial dilation and diastolic dysfunction although the causative mechanisms are not completely understood. In this study we showed for the first time that increase in epicardial fat thickness is significantly correlated with atria enlargement and impairment in diastolic filling in morbidly obese subjects.. AB - Obesity is associated with atrial dilation and diastolic dysfunction although the causative mechanisms are not completely understood. In this study we showed for the first time that increase in epicardial fat thickness is significantly correlated with atria enlargement and impairment in diastolic filling in morbidly obese subjects.. KW - Diastole. KW - Epicardial adipose tissue. KW - Epicardial fat. KW - ...
https://miami.pure.elsevier.com/en/publications/relationship-of-epicardial-adipose-tissue-with-atrial-dimensions-
Association between Epicardial Fat, Metabolic Syndrome and ObesityAssociation between Epicardial Fat, Metabolic Syndrome and Obesity
Epicardial fat is true visceral fat deposited around sub epicardial coronary vessels; it has been implicated in the development of coronary atherosclerosis. Epicardial fat has been also associated with insulin resistance. Trans thoracic echocardiography provides a reliable measurement of epicardial fat thickness. Objective: To evaluate the association between epicardial fat thickness with metabolic syndrome and anthropometric parameters of adiposity. Methods: We assessed 70 patients who underwent echocardiography; the epicardial fat thickness on the free wall of the right ventricle was measured at end-diastole from the parasternal long-axis views of 3 cardiac cycles with Aloka Alfa 6 equipment (Japan), by 2 cardiologists who were unaware of the clinical data. Metabolic syndrome was defined according with the International Diabetes Federation criteria. The association between epicardial fat thicknesses with metabolic syndrome was evaluated with the fisher exact test, whereas its correlation with body
https://www.ommegaonline.org/article-details/Association-between-Epicardial-Fat-Metabolic-Syndrome-and-Obesity/654
Epicardium-derived cells: a new source of regenerative capacity. - PubMed - NCBIEpicardium-derived cells: a new source of regenerative capacity. - PubMed - NCBI
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/20884787?dopt=Abstract
Tobacco smoking and cytokine levels in human epicardial adipose tissue: Impact of smoking cessation | Masarykova univerzitaTobacco smoking and cytokine levels in human epicardial adipose tissue: Impact of smoking cessation | Masarykova univerzita
Background and aims Epicardial adipose tissue (EAT) is a source of a number of cytokines which could act in the pathogenesis of coronary artery disease (CAD). The potential relationship between known cardiovascular risk factors, such as smoking, dyslipidaemia or diabetes mellitus and EAT humoral signalling, has not been fully elucidated. Therefore, we designed and conducted a cross-sectional study to determine whether selected cardiovascular risk factors are linked to levels of cytokines in epicardial and subcutaneous adipose tissue (SAT). Methods Samples of SAT and EAT were collected from consecutive patients undergoing scheduled cardiac surgery. Tissue concentrations of tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), adipocyte fatty acid-binding protein, leptin, and adiponectin were determined by ELISA. Results We enrolled 140 patients. TNF-alpha and IL-6 concentrations in EAT and SAT were significantly higher in current smokers (CS) than in never smokers (NS) and former ...
https://www.muni.cz/vyzkum/publikace/1366449
The Pericardium Channel, Self Love and Relationships
The name Pericardium comes from Latin Peri (around) and Cardium (heart). Often translated from Chinese as Heart Protector, Spirit Protector, or Circulation/Sex the Pericardium is associated with the Fire element and the Heart. The Pericardium protects the Heart from emotional trauma, constricts the chest to protect the Heart, and helps to express the Joy of the Heart. The pericardium helps regulate circulation in the major blood vessels running in and out of the heart. The network of the Pericardium includes the pericardial sac, the Pericardium meridian, the small intestine, and parts of the brain associated with the Pericardium channel.. Pericardium Psycho-spiritual qualities: One could say the function of the Pericardium is primarily psychological, as it rules our relationships and the emotional issues around them. Emotionally, pericardium energy is related to the loving feelings associated with sex, thereby linking the physical and emotional aspects of sexual activity. It does this by ...
http://fiveseasonsmedicine.com/the-pericardium-channel-self-love-and-relationships/
The relationship of epicardial adipose tissue thickness to clinical and biochemical features in women with polycystic ovary...
The amount of epicardial adipose tissue (EAT), a component of body visceral adiposity, has been linked to the presence and severity of cardiovascular disease through multiple mechanisms. Polycystic ovary syndrome (PCOS) is characterized by insulin resistance and subclinical inflammation, which participate in the mechanism of atherosclerosis. We searched if the patients with PCOS have increased EAT thickness (EATT), along with its relation to the measures of adiposity and insulin sensitivity. A total of 41 subjects with PCOS and 46 age and body mass index (BMI) matched healthy controls were enrolled. EAT was measured by echocardiography above the free wall of the right ventricle. Insulin resistance was assessed by homeostasis model assessment of insulin resistance (HOMA-IR) formula, and plasma adiponectin level was measured by ELISA. Compared to healthy controls EATT and HOMA-IR score were significantly higher (p=0.0001 for both) while plasma adiponectin concentration was significantly lower ...
https://avesis.acibadem.edu.tr/yayin/90ba2760-0b6d-40d2-8d1c-c3bfadc50d01/the-relationship-of-epicardial-adipose-tissue-thickness-to-clinical-and-biochemical-features-in-women-with-polycystic-ovary-syndrome
Quantification of epicardial adipose tissue in patients undergoing hybrid ablation for atrial fibrillation<...
TY - JOUR. T1 - Quantification of epicardial adipose tissue in patients undergoing hybrid ablation for atrial fibrillation. AU - Vroomen, Mindy. AU - Olsthoorn, Jules R.. AU - Maesen, Bart. AU - LEspoir, Vladimir. AU - La Meir, Mark. AU - Das, Marco. AU - Maessen, Jos G.. AU - Crijns, Harry J. G. M.. AU - Verheule, Sander. AU - Pison, Laurent. PY - 2019/7. Y1 - 2019/7. KW - Atrial fibrillation. KW - Epicardial adipose tissue. KW - Epicardial fat. KW - Hybrid ablation. KW - Outcome. KW - PERICARDIAL FAT. KW - CATHETER. U2 - 10.1093/ejcts/ezy472. DO - 10.1093/ejcts/ezy472. M3 - Article. C2 - 30753389. VL - 56. SP - 79. EP - 86. JO - European Journal of Cardio-Thoracic Surgery. JF - European Journal of Cardio-Thoracic Surgery. SN - 1010-7940. IS - 1. ER - ...
https://cris.maastrichtuniversity.nl/en/publications/quantification-of-epicardial-adipose-tissue-in-patients-undergoin
Impact of location of epicardial adipose tissue, measured by coronary artery calcium-scoring computed tomography on obstructive...
TY - JOUR. T1 - Impact of location of epicardial adipose tissue, measured by coronary artery calcium-scoring computed tomography on obstructive coronary artery disease. AU - Wu, Fu Zong. AU - Huang, Yi Luan. AU - Wang, Yen Chi. AU - Lin, Huey Shyan. AU - Chen, Chien Shung. AU - Ju, Yu Jen. AU - Chiou, Kuan Rau. AU - Cheng, Chin Chang. AU - Wu, Ming Ting. PY - 2013/10/1. Y1 - 2013/10/1. N2 - Epicardial adipose tissue (EAT) is considered to play a role in the pathogenesis of coronary atherosclerosis. However, whether total EAT volume or location-specific EAT thickness may be a better predictor of obstructive coronary artery disease (CAD) is inconclusive. We investigated whether the total volume or location-specific thickness of EAT measured on computed tomography (CT) could be a useful marker of CAD on top of clinical risk factors and Agatston score. Two hundred eight consecutive subjects with clinical suspicion of CAD receiving coronary arterial calcium (CAC)-scoring CT and CT coronary ...
https://tmu.pure.elsevier.com/en/publications/impact-of-location-of-epicardial-adipose-tissue-measured-by-coron
Epicardial Adipose Tissue Removal Potentiates Outward Remodeling and Arrests Coronary Atherogenesis<...
TY - JOUR. T1 - Epicardial Adipose Tissue Removal Potentiates Outward Remodeling and Arrests Coronary Atherogenesis. AU - McKenney-Drake, Mikaela L.. AU - Rodenbeck, Stacey D.. AU - Bruning, Rebecca S.. AU - Kole, Ayeeshik. AU - Yancey, Kyle W.. AU - Alloosh, Mouhamad. AU - Sacks, Harold S.. AU - Sturek, Michael. PY - 2017/5. Y1 - 2017/5. N2 - Background Pericoronary epicardial adipose tissue (cEAT) serves as a metabolic and paracrine organ that contributes to inflammation and is associated with macrovascular coronary artery disease (CAD) development. Although there is a strong correlation in humans between cEAT volume and CAD severity, there remains a paucity of experimental data demonstrating a causal link of cEAT to CAD. The current study tested the hypothesis that surgical resection of cEAT attenuates inflammation and CAD progression. Methods Female Ossabaw miniature swine (n = 12) were fed an atherogenic diet for 8 months and randomly allocated into sham (n = 5) or adipectomy (n = 7) ...
https://indiana.pure.elsevier.com/en/publications/epicardial-adipose-tissue-removal-potentiates-outward-remodeling-
Decrease of the Pericardial Fat around the Heart has a Positive Correlation with Improvement of Left Ventricular Performance ...
In this study there was a positive correlation between improvement of left ventricular function and decrease of pericardial fat around heart. This improvement of left ventricular function happened rapidly, after only eight weeks on VLCD. However, the mechanism behind this phenomenon is unknown.. Pericardial fat is located between visceral and parietal pericardium. The anatomical close connection between excess fat around the heart might increase the weight of the left ventricle thus increasing the effort of involved in pumping.. Epicardial fat and pericardial fat are embryologically different. Vascularization is also different between these two layers. Vascularization for the epicardial adipose tissue is supplied by branches of the coronary arteries. Pericardial adipose tissue gets its Vascularization from non-coronary sources. At least one part of epicardial fat is physiological. However, excess epicardial fat that is seen in many obese persons may be harmful on heart function.. The fat around ...
http://googlescholar.medcraveonline.com/scholars/article_fulltext/4123
CDX1 - wikidocCDX1 - wikidoc
This gene is a member of the caudal-related homeobox transcription factor family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.[2] CDX1 has also been shown to play an important role in embryonic epicardial development. It has been demonstrated that CDX proteins suppress cardiac differentiation in both zebrafish and mouse embryonic stem cells, but the overall mechanism for how this happens is poorly understood.[5] However, CDX1 has been shown to be transiently expressed in the embryonic heart 11.5 days post coitum (dpc). This transient expression is thought to induce epicardial epithelial-to-mesynchemal transition and thus proper cardiovascular formation. It has been shown that low-dose CDX1 induction caused enhanced migration and differentiation of epicardium-derived cells into vascular ...
https://www.wikidoc.org/index.php?title=CDX1&oldid=1420493
Epicardial and pericardial adipose tissues are associated with reduced diastolic and systolic function in type 2 diabetes -...
The aim of this study was to investigate the association of epicardial (EAT) and pericardial (PAT) adipose tissues with myocardial function in type 2 diabetes (T2D). EAT and PAT were measured by ultrasound in 770 patients with T2D and 234 age- and sex-matched non-diabetic controls. Echocardiography was performed, including tissue Doppler imaging and 2D speckle tracking. Patients with T2D versus controls had increased EAT (4.6 ± 1.8 mm vs. 3.4 ± 1.2 mm, P , 0.0001) and PAT (6.3 ± 2.8 mm vs. 5.3 ± 2.4 mm, P , 0.0001). EAT and PAT were associated with structural cardiac measures both in T2D patients and controls (all P , 0.043), but only in T2D patients with functional measures: PAT was associated with impaired global longitudinal strain [beta coefficient (SE)] [0.11% (0.04), P = 0.002], while EAT was associated with reduced diastolic function by lateral early diastolic myocardial velocity (e lat ) [-0.31 (0.05) cm/s, P = 0.001], mitral inflow velocities: peak early (E)/peak atrial (A) ratio ...
https://research.regionh.dk/en/publications/epicardial-and-pericardial-adipose-tissues-are-associated-with-reduced-diastolic-and-systolic-function-in-type-2-diabetes
Heart pericardium surface, SEM - Stock Image C032/0593 - Science Photo LibraryHeart pericardium surface, SEM - Stock Image C032/0593 - Science Photo Library
Surface of the heart pericardium, coloured scanning electron micrograph (SEM). The pericardium is a double-walled, membranous sac surrounding the heart. The pericardium has a tough outer fibrous layer (fibrous pericardium) and a delicate serous layer (serous pericardium). Shown here is the outer surface of the fibrous pericardium that is composed of connective tissue (fibronectin, collagen and laminin). Flattened squamous epithelial cells (from the upper serous layer) can be seen protruding through the fibrous pericardial layer. The inner serous pericardial layer is the wall adjacent to the heart (not seen). It is split into two layers, the epicardium (just above the heart) and the parietal layer. Between the two layers is the pericardial cavity, which contains serous fluid. The serous pericardium lubricates the heart, preventing friction. Magnification: x5,000 when shortest axis printed at 25 millimetres. - Stock Image C032/0593
http://www.sciencephoto.com/media/797416/view
JDB | Free Full-Text | Epicardial Lineages and Cardiac Repair | HTMLJDB | Free Full-Text | Epicardial Lineages and Cardiac Repair | HTML
The death of cardiac myocytes resulting from myocardial infarction is a major cause of heart failure worldwide. Effective therapies for regenerating lost cardiac myocytes are lacking. Recently, the epicardium has been implicated as a source of inflammatory cytokines, growth factors and progenitor cells that modulate the response to myocardial injury. During embryonic development, epicardially-derived cells have the potential to differentiate into multiple cardiac lineages, including fibroblasts, vascular smooth muscle and potentially other cell types. In the healthy adult heart, epicardial cells are thought to be generally quiescent. However, injury of the adult heart results in reactivation of a developmental gene program in the epicardium, which leads to increased epicardial cell proliferation and differentiation of epicardium-derived cells (EPDCs) into various cardiac lineages. Recent work suggests that epicardial reactivation after injury is accompanied by, and contributes to, a robust inflammatory
https://www.mdpi.com/2221-3759/1/2/141/htm
Increased Regional Epicardial Fat Volume Associated with Reversible Myocardial Ischemia in Patients with Suspected Coronary...
Epicardial adipose tissue is a source of pro-inflammatory cytokines and has been linked to the development of coronary artery disease. No study has systematically assessed the relationship between local epicardial fat volume (EFV) and myocardial perf
http://www.biomedsearch.com/nih/Increased-Regional-Epicardial-Fat-Volume/25339129.html
Patent US6206004 - Treatment method via the pericardial space - Google PatentsPatent US6206004 - Treatment method via the pericardial space - Google Patents
A method for treating the heart and associated vessels and tissues, by controlling the temperature of the pericardial space and/or introducing therapeutic agents, drugs or the like thereto, includes providing a fluid, liquid(s), gas(es) or mixtures thereof, with or without therapeutic agents, drugs or the like, and heating and/or cooling, this fluid. At a time proximate to the heating and/or cooling of the fluid, the pericardial space is accessed by pericardiocentesis, such that the pericardium is punctured and the pericardial space is instrumentized at a location, and in particular, a location where treatment is desired. The heated and/or cooled fluid is then delivered to the pericardial space. At a time after delivery, the fluid is withdrawn from the pericardium, through either the same catheter, or through another catheter at different point along the pericardium, that was also instrumentized (catheterized) by standard pericardiocentesis procedures. This delivery and withdrawal of the fluid may be
http://www.google.com/patents/US6206004?dq=ascentive
The role of exercise combined with tocilizumab in visceral and epicardial adipose tissue and gastric emptying rate in...
BACKGROUND: Exercise reduces the amount of visceral adipose tissue (VAT) and the risk of cardiometabolic diseases. The underlying mechanisms responsible for these exercise-induced adaptations are unclear, but they may involve lipolytic actions of interleukin-6 (IL-6). Contracting skeletal muscles secrete IL-6, leading to increased circulating IL-6 levels in response to exercise. The aim of this study is to investigate whether IL-6 is involved in mediating the effects of exercise on visceral and epicardial adipose tissue volume and glycaemic control.. METHODS/DESIGN: Seventy-five physically inactive males and females aged , 18 years with a waist-to-height ratio , 0.5 and/or waist circumference ≥ 88 cm (females) or ≥ 102 cm (males) are being recruited to participate in a 12-week intervention study. Participants are randomly allocated to one of five groups (1:1:1:1:1). Two groups consist of supervised endurance exercise training combined with the IL-6 blocker tocilizumab (ET) or saline used as ...
https://research.regionh.dk/da/publications/the-role-of-exercise-combined-with-tocilizumab-in-visceral-and-epicardial-adipose-tissue-and-gastric-emptying-rate-in-abdominally-obese-participants
The independent relationship of epicardial adipose tissue with carotid intima-media thickness and endothelial functions: the...
Background Hypertension, identifiable by elevated blood pressure (BP), is a heterogeneous multifactorial disorder. Epicardial adipose tissue (EAT), a special fat depot that is related to visceral fat rather than total adiposity, shares the same microcirculation with myocardial tissue and coronary vessels. Recent studies have identified EAT as an active organ, which secretes several mediators, called adipokines, affecting the vascular system. The aim of this study was to evaluate the potential association between EAT and BP, endothelial function, carotid intima-media thickness (CIMT), and pulse wave velocity (PWV) independent of conventional and novel metabolic risk factors in patients with previously untreated hypertension. ...
https://avesis.erdogan.edu.tr/yayin/ff91f24e-debe-44cf-8b6e-7431c516d6b7/the-independent-relationship-of-epicardial-adipose-tissue-with-carotid-intima-media-thickness-and-endothelial-functions-the-association-of-pulse-wave-velocity-with-the-active-facilitated-arterial-conduction-concept
Phenol topically applied to canine left ventricular epicardium interrupts sympathetic but not vagal afferents<...
TY - JOUR. T1 - Phenol topically applied to canine left ventricular epicardium interrupts sympathetic but not vagal afferents. AU - Barber, M. J.. AU - Mueller, T. M.. AU - Davies, B. G.. AU - Zipes, D. P.. PY - 1984/1/1. Y1 - 1984/1/1. N2 - The intracardiac pathways carrying the cardiovascular reflex responses mediated by cardiac sympathetic and vagal afferent fibers were examined in this study. We investigated the response to epicardial applications of bradykinin (5 μg) and nicotine (50 μg) before and after regional epicardial applications of 85% phenol in chloralose anesthetized open-chest dogs. Bradykinin stimulated sympathetic afferents, while nicotine stimulated vagal afferents. Topical applications of phenol were used to interrupt these pathways. Before phenol encircling, bradykinin significantly increased - whereas nicotine significantly decreased - mean arterial blood pressure when applied at the same sites. After phenol, nicotine applied to all sites within and outside the phenol ...
https://indiana.pure.elsevier.com/en/publications/phenol-topically-applied-to-canine-left-ventricular-epicardium-in
Pericardium - Surgikor | Bone Grafting Material - Allograft - Cortical CancellousPericardium - Surgikor | Bone Grafting Material - Allograft - Cortical Cancellous
The oral cavity is a demanding and dynamic environment for healing, which is why pericardium products are considered the gold standard in protecting the delicate tissues of the teeth, gums and jaw following oral surgery.. Pericardium is a pliant, sterile membrane which naturally weathers the moisture and mechanical stresses of the mouth as dental surgery heals. A variety of dental implant procedures indicate the use of pericardium as a cornerstone of aftercare, and leading surgeons rely on its strength and versatility in a variety of settings.. At Surgikor, our pericardium products are easy to use and vetted against the most stringent standards in medical production. Click here or here to see pericardium in different sizes and price points, and feel free to contact us with any questions about other dental surgery materials... ...
http://surgikor.com/pericardium-3/
Difference Between Visceral and Parietal Pericardium l Visceral vs Parietal PericardiumDifference Between Visceral and Parietal Pericardium l Visceral vs Parietal Pericardium
What is the difference between Visceral and Parietal Pericardium? Pericardium is the inner layer of serous pericardium; parietal pericardium is the outer layer
http://www.differencebetween.com/difference-between-visceral-and-vs-parietal-pericardium/
The measurement of epicardial fat thickness is an index of cardiometabolic risk in patients with adrenal incidentaloma
An augmented cardiovascular risk is present in adrenal incidentalomas (AI), as in overt hypercortisolism. Recent studies recommended epicardial fat (EF) thickness as a new marker of visceral adiposity and an indicator of cardiometabolic risk.. In this study, we evaluated the possible relationship between EF thickness, indices of left ventricular (LV) hypertrophy and adipocytokines levels in AI.. We studied 26 patients with AI (62.3±10.3 years, BMI 27.2±3.3 kg/m2, mean±S.D.) and 21 controls matched for age and BMI (59.9±6.7 years, BMI 25.3±3.6 kg/m2). In all patients basal ACTH, cortisol, urinary free cortisol, IL-6 and resistin levels were measured. One mg dexamethasone test was performed. EF thickness and indices of LV hypertrophy were assessed by transthoracic echocardiography.. Four patients had a subclinical Cushing s syndrome (SCS) and 22 had non functioning masses. Overall, the prevalence of arterial hypertension was 69.2%, type 2 diabetes was 19.2%, dyslipidemia 26.9%, overweight 50% ...
http://www.endocrine-abstracts.org/ea/0022/ea0022p39.htm
One-Stage Correction of Complex Aortic Arch and Descending Aorta Dysplasia Combined Intracardiac Anomalies with a Median...
For patients with interrupted aortic arches, distal aortic arch dysplasia, long coarctation segments, or obvious vascular calcification and older children and adults, we adopted a Gore-Tex vascular graft bypass (Figure 1). First, we performed end-to-side anastomosis between the Gore-Tex vascular graft and normal descending aorta distal from the coarctation, and the anastomosis was continuously sutured with 5/0 prolene line, tightened and lined with strips of autologous pericardium. Next, we restored the cardiopulmonary bypass, allowed perfusion, and warmed up the blood. After expelling gas from the vascular graft and clamping the said graft, we performed end-to-side anastomosis between the Gore-Tex vascular graft and normal ascending aorta. We only performed end-to-side anastomosis between the vascular graft and normal descending aorta with circulatory arrest. This can decrease the total surgical time and facilitate good anastomosis. Lining with stripped autologous pericardium can prevent vessel ...
https://www.clinicsinsurgery.com/full-text/cis-v3-id2173.php
Right heart pressure does not equal pericardial pressure in the potassium chloride-arrested canine heart in situ. | CirculationRight heart pressure does not equal pericardial pressure in the potassium chloride-arrested canine heart in situ. | Circulation
Recently proposed concepts of pericardial surface pressure, as opposed to liquid pressure, have advanced our understanding of the relationship between pericardial and heart chamber pressures. However, the subsequent suggestion that right heart intracavitary pressure equals, or nearly equals, pericardial surface pressure is not strictly consistent with the physiology of pericardial constraint. If right heart pressure equals pericardial surface pressure, then transmural right heart pressure equals zero. Because of the difficulty in measuring pericardial pressure directly in the beating heart we designed an experiment in the recently arrested canine heart in situ to measure pericardial pressure indirectly and to test the hypothesis that right heart transmural pressure is zero under reasonably physiologic, static equilibrium conditions. According to a static equilibrium analysis of the pressures acting across the walls of the heart, at a given volume the change in right heart pressure caused by ...
http://circ.ahajournals.org/content/76/2/357
What happens when the pericardium of the heart is removed - Doctor answersWhat happens when the pericardium of the heart is removed - Doctor answers
What happens when the pericardium of the heart is removed - How does the pericardium improve the efficiency of the heart? By not interfering. A healthy pericardium is a very flexible, thin tissue that is just there. it generally serves little purpose, other than to allow the chambers of the heart to expand outwards in a normal fashion, without resistance, as they fill with blood. If pericardium becomes inflamed, thickened or hardened, the heart loses this outward mobility, and pressure rises greatly as the heart tries to fill.
https://www.healthtap.com/topics/what-happens-when-the-pericardium-of-the-heart-is-removed
Weight of Pericardial Fat on Coronaropathy | Arteriosclerosis, Thrombosis, and Vascular BiologyWeight of Pericardial Fat on Coronaropathy | Arteriosclerosis, Thrombosis, and Vascular Biology
The regional distribution of adipose tissue (AT) is a major determinant of metabolic and cardiovascular diseases. The mass of fat in the visceral area associates independently of obesity with the development and progression of cardiovascular diseases in a series of clinical and epidemiological studies.1 This led to the concept of a pathophysiological link between abdominal obesity and metabolic syndrome. More recently, fat depots localized around the heart, highly variable among individuals, were proposed to contribute to the pathogenesis of coronaropathy independently of other visceral depots (ie, in the omental and mesenteric area).2,3 The study by Greif et al3a in this issue of Arteriosclerosis, Thrombosis, and Vascular Biology highlights the association between pericardial adipose tissue (PAT) and the number of atherosclerotic plaques evaluated concomitantly by Dual source CT scan. This measurement was qualitatively interpretable in 264 consecutive patients with a large range of age, a ...
http://atvb.ahajournals.org/content/29/5/615
Notch Signaling Regulates Smooth Muscle Differentiation of Epicardium-Derived CellsNovelty and Significance | Circulation...Notch Signaling Regulates Smooth Muscle Differentiation of Epicardium-Derived CellsNovelty and Significance | Circulation...
Given the complexity of Notch receptor and ligand expression during development of the epicardium and the coronary system, we assumed that redundancy between receptors and ligands, respectively, may necessitate the simultaneous removal of 2 or more genes to assign a Notch signaling requirement to these processes. We therefore decided to analyze the phenotypic consequences of removal of Rbpj that encodes a unique intracellular mediator of (canonical) Notch signaling.14 Because Rbpj-deficiency results in early embryonic lethality in mice,15 we used a tissue-specific inactivation approach using a Tbx18cre line generated in our laboratory and a floxed Rbpj allele to analyze Notch signaling function in the PEO and epicardium.10,12 The T-box transcription factor gene Tbx18 is strongly expressed in the PEO at E9.5, and in the epicardium until E16.5. Other cardiac expression domains include the sinus horn mesenchyme/myocardium, and the myocardium of the left ventricle and the interventricular septum ...
http://circres.ahajournals.org/content/108/7/813
John Jeffrey Carr M.D., M.Sc. - Publications - Labnodes - The Vanderbilt Research Network
Dr. John Jeffrey Carr is the Cornelius Vanderbilt Professor of Radiology and Radiological Sciences and Professor of Biomedical Informatics and Cardiovascular Medicine. Clinically, he specializes in non-invasive cardiovascular imaging computed tomography (CT) and magnetic resonance imaging (MRI). He is a physician-scientist using non-invasive imaging to not only identify and predict disease before it becomes clinical evident. Dr. Carrs research is focused on developing quantitative imaging phenotypes and biomarkers applicable to population-based and personalized medicine. His current research is using advanced computed tomography (CT) techniques to measure coronary blood vessels, coronary plaque and the surrounding pericardial adipose tissue (fat cells) as a means to better understand who is at highest risk for myocardial infarction (heart attacks) and heart failure later in life (NIH-NHLBI 7R01HL098445-05). This project is part of the NHLBI Coronary Artery Risk Development in Young Adults Study
https://labnodes.vanderbilt.edu/member/publications/id/10852/keyword_id/11911/keyword_name/TreatmentOutcome?page=2
retired docs thoughts: Is the link between atrial fibrillation and obesity epicardial fat?retired docs thoughts: Is the link between atrial fibrillation and obesity epicardial fat?
The epidemiologic data having established a sound correlation between obesity and risk of atrial fibrillation , the electrophysiologic (EP) cardiologists began to speculate on possible mechanistic explanations. These so far have included activation of pro-fibrotic pathways,atrial fibrosis, abnormal connexin, ( gap junction proteins necessary for heart cell action potential propagation) diastolic dysfunction , paracrine effect due to proximity of epicardial fat to myocytes, and more recently detailed scrutiny of the role or roles of epicardial fat to which has been assigned the ironic designation, of EAT (epicardial adipose tissue) in deleterious remodeling of the left atrium ...
http://mdredux.blogspot.com/2019/01/is-link-between-atrial-fibrillation-and.html
Pericardium - OMS SupplyPericardium - OMS Supply
Resorbable Membranes Pericardium Pericardium membrane comes from the sac surrounding the heart. Pericardium functions as a thin pliable membrane that will lay flat on the grafting site. Select from dropdown. Choose from: DP101 | Size 1.0 x 1.0cm DP152 | Size 1.5 x 2.0cm DP203 | Size 2.0 x 3.0cm
https://www.omssupply.com/collections/speciality-graft/products/pericardium
Figure1 | Phrenic Nerve Limitation During Epicardial Catheter Ablation of Ventricular Tachycardia | JACC: Clinical...Figure1 | Phrenic Nerve Limitation During Epicardial Catheter Ablation of Ventricular Tachycardia | JACC: Clinical...
This article requires a subscription or purchase to view the full text. If you are a subscriber or member, click Login or the Subscribe link (top menu above) to access this article.. ...
http://electrophysiology.onlinejacc.org/content/5/1/81/F1
Epicardial Activation of Left Ventricular Wall Prolongs QT Interval and Transmural Dispersion of Repolarization | CirculationEpicardial Activation of Left Ventricular Wall Prolongs QT Interval and Transmural Dispersion of Repolarization | Circulation
Our mathematical simulation and experimental data complement each other and provide evidence in support of the hypothesis that intrinsic heterogeneity exists within the ventricular myocardium and that this electrical heterogeneity is amplified when the normal direction of activation of the ventricular wall is reversed. Epicardial activation augments TDR because the epicardial action potential activates and repolarizes earlier and the M cells with the longest APD located in the deep subendocardium activate and repolarize later compared with endocardial activation of the ventricular wall. The additional conduction delay encountered between epicardial and M regions during epicardial stimulation contributes to the amplification of TDR. The extra delay in conduction between epicardium and the M region is likely due to the increased tissue resistivity in the deep subepicardium of the canine heart previously described by our group.15 Conduction time is briefer in the endocardial to epicardial ...
http://circ.ahajournals.org/content/109/17/2136
Leicester Research Archive: Epicardial Adipose Tissue as a Source of Nuclear Factor-B and c-Jun N-Terminal Kinase Mediated...
Context: Visceral adipose tissue (AT) is known to confer a significantly higher risk of type 2 diabetes and cardiovascular disease. Epicardial AT has been shown to be related to cardiovascular disease and myocardial function through unidentified mechanisms. Epicardial AT expresses an inflammatory profile of proteins; however, the mechanisms responsible are yet to be elucidated. Objectives: The objectives of the study were to: 1) examine key mediators of the nuclear factor-B (NFB) and c-Jun N-terminal kinase (JNK) pathways in paired epicardial and gluteofemoral (thigh) AT from coronary artery disease (CAD) and control patients and 2) investigate circulating endotoxin levels in CAD and control subjects. Design: Serums and AT biopsies (epicardial and thigh) were obtained from CAD (n = 16) and non-CAD (n = 18) patients. Inflammation was assessed in tissue and serum samples through Western blot, real-time PCR, ELISAs, and activity studies. Results: Western blotting showed epicardial AT had ...
https://lra.le.ac.uk/handle/2381/8581
Protecting the Heart in Obesity: Role of ACE2 and Its Partners | DiabetesProtecting the Heart in Obesity: Role of ACE2 and Its Partners | Diabetes
Although Patel et al. (13) have discovered an important role for epicardial adipose tissue and ACE2/Ang 1-7 deficiency in obesity-related cardiomyopathy, there are some aspects that warrant further consideration. First, although it is clearly shown that in the absence of ACE2, epicardial adipose tissue differentiates into a proinflammatory phenotype, the authors do not reveal whether other adipose depots and organs also become inflamed in the model studied. This is important because it may be possible that ubiquitous ACE2 knockout leads to a generalized inflammatory response, including in the myocardium, which could directly impact on cardiac dysfunction independently of epicardial inflammation. However, cross talk between inflamed epicardial adipocytes and cardiomyocytes/fibroblasts may amplify underlying cardiac injury in ACE2 knockout mice. Such cross talk is evidenced by the findings that epicardial inflammation is linked to aberrant myocardial AMPK signaling and insulin resistance (13). To ...
https://diabetes.diabetesjournals.org/node/7465.full.print
From the epicardial adipose tissue to vulnerable coronary plaques.
Thin cap fibroatheromas (TCFAs) are thought to be the most common underlying substrate in patients suffering acute coronary thrombotic events. Recently, an interesting association between TCFAs and a particular depot of visceral fat called epicardial
http://www.biomedsearch.com/nih/From-epicardial-adipose-tissue-to/23675552.html
Rationale Epicardial Adipose Tissue (EAT) volume as dependant on chest computed | Targeting NRAS in Melanoma and Acute...Rationale Epicardial Adipose Tissue (EAT) volume as dependant on chest computed | Targeting NRAS in Melanoma and Acute...
41044-12-6 manufacture only pack-years (B?=?0.6, 95% CI: 0.5C1.3), BMI (B?=?7.8, 95% CI: 5.7C9.9) and 6 MWD (B?=??0.2, 95% CI: ?0.3C?0.1), predicted EAT volume. Conclusions EAT volume is usually increased in COPD patients and is independently associated with smoking history, BMI and exercise capacity, all modifiable risk factors of future cardiovascular events. EAT volume could be a non-invasive marker of COPD patients at high risk for future cardiovascular events. Introduction Chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD) are two of the top causes of death worldwide [1]. COPD has been described as an independent risk factor for CVD (2) and the latter is a major cause of mortality in COPD, particularly in patients with moderate to moderate disease [3]C[5]. Non-invasive CVD markers may be important to identify COPD patients who are at high risk to develop future cardiovascular events. Beyond the traditional non-invasive CVD risk factors, several other have been ...
http://scienceofgreathealth.com/rationale-epicardial-adipose-tissue-eat-volume-as-dependant-on-chest-computed/
Epicardial Adipose Tissue in the General Middle-aged Population and Its Association With Metabolic SyndromeEpicardial Adipose Tissue in the General Middle-aged Population and Its Association With Metabolic Syndrome
Among participants without MS, the prevalence of EAT ≥ 5mm significantly increased with age (OR , 65 years vs 45-54 years=8.22; 95%CI, 3.90-17.35; P for trend,.001). Increasing EAT quintiles were significantly associated with MS (OR fifth quintile vs first quintile=3.26; 95%CI, 1.59-6.71; P for trend=.001).. Considering the different MS criteria, increasing quintiles of EAT were independently associated with low high-density lipoprotein cholesterol (OR fifth quintile vs first quintile=2.65; 95%CI, 1.16-6.05; P for trend=.028), high triglycerides (OR fifth quintile vs first quintile=2.22; 95%CI, 1.26-3.90; P for trend=.003), and elevated waist circumference (OR fifth quintile vs first quintile=6.85; 95%CI, 2.91-16.11; P for trend,.001).. CONCLUSIONS: ...
https://www.cun.es/en/research/scientific-publications/epicardial-adipose-tissue-general-middle-aged-population-association-metabolic-syndrome
HFWM: - Title: Adiponectin and 4-hydroxynonenal as messengers in the cross-talk between the heart and epicardial adipose tissue...HFWM: - Title: Adiponectin and 4-hydroxynonenal as messengers in the cross-talk between the heart and epicardial adipose tissue...
We use cookies to ensure that we give you the best experience on our website. If you click Continue well assume that you are happy to receive all cookies and you wont see this message again. Click Find out more for information on how to change your cookie settings ...
https://www.rdm.ox.ac.uk/publications/472294
Primary Mesothelioma of the Pericardium - PDFPrimary Mesothelioma of the Pericardium - PDF
Primary Mesothelioma of the Pericardium BY JOHN THOMAS, M.Dl., AND JAMES M. IPHYTHYO,1X, M.D. MIesotheliomas of the pericardium are one of the causes of sanguineous pericardial effusion. C(linical and
http://docplayer.net/1890522-Primary-mesothelioma-of-the-pericardium.html
Epicardium - wikidoc
Epicardium describes the outer layer of heart tissue (from Greek; epi- outer, cardium heart). When considered as a part of the pericardium, it is the inner layer, or visceral pericardium. Its largest constituent is connective tissue and functions as a protective layer. The visceral pericardium apparently produces the pericardial fluid, which lubricates motion between the inner and outer layers of the pericardium. During ventricular contraction, the wave of depolarization moves from endocardial to epicardial surface. ...
http://es.wikidoc.org/index.php/Epicardium
Product Catalog
Email , Print SKU: PC0404SNBIO. SUPPLE PERI-GUARD Pericardium Patch is prepared from bovine pericardium which is cross-linked with glutaraldehyde. SUPPLE PERI-GUARD Pericardium Patch is chemically sterilized using ethanol and propylene oxide. SUPPLE PERI-GUARD Pericardium Patch is packaged in a container filled with sterile, non-pyrogenic water containing propylene oxide. The contents of the unopened, undamaged container are sterile. SUPPLE PERI-GUARD Pericardium Patch is available in four sizes. ...
https://ecatalog.baxter.com/ecatalog/loadproduct.html?cid=20016&lid=10001&hid=20001&pid=821643
Epicardial adipose tissue thickness is increased in patients with cardiac syndrome X | AVESÄ°SEpicardial adipose tissue thickness is increased in patients with cardiac syndrome X | AVESÄ°S
Background: Cardiac syndrome X (CSX) is defined as normal coronary arteries with angina pectoris and a positive stress test. Epicardial adipose tissue (EAT) plays an important role in inflammatory process in cardiovascular system, therefore EAT may affect the pathogenesis of different cardiovascular disease. The aim of this study was to investigate the EAT thickness in patients with CSX and compare normal subjects. Methods: We prospectively enrolled 30 consecutive patients with CSX. The control group consisted of 30 age and sex-matched individuals with anginal chest pain and a negative treadmill or myocardial perfusion scan test. EAT thickness was measured by transthoracic echocardiography. Results: There were no differences in baseline clinical, biochemical and echocardiographic characteristics between CSX patients and the control group. Patients with CSX had significantly increased EAT thickness than those of the controls (3.43 +/- 0.88 vs. 2.34 +/- 0.89 mm, p=0.0001). Conclusion: We found ...
https://avesis.ktu.edu.tr/yayin/3b56a998-d5b5-4e34-935b-79b0eb7a08e4/epicardial-adipose-tissue-thickness-is-increased-in-patients-with-cardiac-syndrome-x
Lack of Association between Epicardial Fat Volume and Extent of Coronary Artery Calcification, Severity of Coronary Artery...
TY - JOUR. T1 - Lack of Association between Epicardial Fat Volume and Extent of Coronary Artery Calcification, Severity of Coronary Artery Disease, or Presence of Myocardial Perfusion Abnormalities in a Diverse, Symptomatic Patient Population. T2 - Results from the CORE320 Multicenter Study. AU - Tanami, Yutaka. AU - Jinzaki, Masahiro. AU - Kishi, Satoru. AU - Matheson, Matthew. AU - Vavere, Andrea L.. AU - Rochitte, Carlos E.. AU - Dewey, Marc. AU - Chen, Marcus Y.. AU - Clouse, Melvin E.. AU - Cox, Christopher. AU - Kuribayashi, Sachio. AU - Lima, Joao A.C.. AU - Arbab-Zadeh, Armin. N1 - Publisher Copyright: © 2015 American Heart Association, Inc. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 2015/3/21. Y1 - 2015/3/21. N2 - Background-Epicardial fat may play a role in the pathogenesis of coronary artery disease (CAD). We explored the relationship of epicardial fat volume (EFV) with the presence and severity of CAD or myocardial perfusion abnormalities in a diverse, ...
https://keio.pure.elsevier.com/en/publications/lack-of-association-between-epicardial-fat-volume-and-extent-of-c
Repair of Intrapericardial Diaphragmatic Hernia during Aortic Surgery in a 78-Year-Old Woman | Texas Heart Institute JournalRepair of Intrapericardial Diaphragmatic Hernia during Aortic Surgery in a 78-Year-Old Woman | Texas Heart Institute Journal
Intrapericardial diaphragmatic hernias are reported very rarely. Those of congenital origin are most often diagnosed in neonates, and those caused by indirect blunt trauma occur chiefly in adults. The latter type can be asymptomatic; however, the results of a computed tomographic scan can yield a definitive diagnosis. Once discovered, these hernias should be corrected to avoid severe sequelae such as bowel strangulation and necrosis, peritonitis, mediastinitis, and cardiac tamponade.. We report the case of a 78-year-old woman who presented for elective ascending aortic aneurysm repair. Computed tomographic angiograms incidentally revealed a large intrapericardial diaphragmatic hernia, which had probably developed years earlier, after a traffic accident. The patient underwent a median sternotomy and repair of the intrapericardial diaphragmatic hernia with use of a bovine pericardial patch, followed by ascending aortic and hemiarch repair, aortic valve repair, and aorto-right coronary artery ...
https://meridian.allenpress.com/thij/article/44/2/150/85438/Repair-of-Intrapericardial-Diaphragmatic-Hernia
Pericardial defect presenting as acute pericarditis. | HeartPericardial defect presenting as acute pericarditis. | Heart
A case of herniation of the left atrial appendage, through a defect in the pericardium, is described in a 16-year-old boy who was below the third percentile for height and weight. The clinical presentation was an acute pericarditis. Widespread inversion of T waves on the electrocardiogram and collapse of the lower lobe of the left lung with pleural effusion developed. Thoracotomy showed strangulation of the atrial appendage which was excised, and the pericardial defect repaired. After operation there was a striking improvement in the electrocardiogram and a rapid gain in weight. Syndromes caused by pericardial defects are reviewed. ...
http://heart.bmj.com/content/37/1/98
Advanced Coronary Atherosclerosis and Fatal Myocardial Infarction in Mild Dyslipidemic, Low Risk Young Man: A Case Report With...Advanced Coronary Atherosclerosis and Fatal Myocardial Infarction in Mild Dyslipidemic, Low Risk Young Man: A Case Report With...
Acute Myocardial infarction (AMI) at a young age (below 45 years) is rare and difficult to predict. We reported a fatal myocardial infarction from advanced atherosclerosis in a healthy young man who had no other major coronary risk factors except mild hypercholesterolemia. Thus, all available systemic risk scores identified him as a low risk candidate for developing a cardiovascular event. Autopsy revealed advanced atherosclerosis in all three major coronary arteries causing acute and old myocardial infarction. Thick epicardial adipose tissue and myocardial bridging of the mid left anterior descending artery were also noted. He frequently used etoricoxib to treat knee and back pain for consecutive five years. Potential mechanisms of sudden death from atherosclerosis, myo- cardial bridging, epicardial adipose tissue and selective COXIB are discussed in more detail below.. ...
https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/222699
Coronary vessel development and insight towards neovascular therapy. - Physiology, Anatomy and Genetics
Formation of the coronary arteries consists of a precisely orchestrated series of morphogenetic and molecular events which can be divided into three distinct processes: vasculogenesis, angiogenesis and arteriogenesis (Risau 1997; Carmeliet 2000). Even subtle perturbations in this process may lead to congenital coronary artery anomalies, as occur in 0.2-1.2% of the general population (von Kodolitsch et al. 2004). Contrary to the previously held dogma, the process of vasculogenesis is not limited to prenatal development. Both vasculogenesis and angiogenesis are now known to actively occur within the adult heart. When the need for regeneration arises, for example in the setting of coronary artery disease, a reactivation of embryonic processes ensues, redeploying many of the same molecular regulators. Thus, an understanding of the mechanisms of embryonic coronary vasculogenesis and angiogenesis may prove invaluable in developing novel strategies for cardiovascular regeneration and therapeutic coronary
https://www.dpag.ox.ac.uk/publications/251941
Epicardial adipose tissue expansion and differentiation status predict myocardial redox state and coronary calcification -...Epicardial adipose tissue expansion and differentiation status predict myocardial redox state and coronary calcification -...
We use cookies to ensure that we give you the best experience on our website. If you click Continue well assume that you are happy to receive all cookies and you wont see this message again. Click Find out more for information on how to change your cookie settings ...
https://www.clahrc-oxford.nihr.ac.uk/publications/571590
Reentry in survived subepicardium coupled to depolarized and inexcitable midmyocardium: insights into arrhythmogenesis in...
BACKGROUND: Delayed ventricular arrhythmias during acute myocardial ischemia (1B arrhythmias) are associated with an increase in tissue impedance and are most likely sustained in a thin subepicardial layer. OBJECTIVE: The goal of this study was to test the hypothesis that heterogeneous uncoupling between depolarized midmyocardium and surviving subepicardium results in heterogeneous refractoriness in the latter, providing the reentry substrate after a premature beat. METHODS: A 3-dimensional bidomain slab was constructed comprising a normal subepicardial layer coupled to a slightly depolarized (-80 to -60 mV) but inexcitable midmyocardium. Experimentally measured tissue impedance served as input for the model. Four stages of heterogeneous uncoupling between the 2 layers were simulated, each corresponding to an experimental ischemic impedance value. Effective refractory periods (ERP), conduction velocities, and inducibility of reentry were examined. RESULTS: Heterogeneous uncoupling resulted in
https://www.neuroscience.ox.ac.uk/publications/291432
YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis |...YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis |...
The Wilms Tumour gene WT1 has important functions during development. Knock-out mice were shown to have defects in the urogenital system and to die at embryonic day E13.5, probably due to heart failure. Using a lacZ reporter gene inserted into a YAC construct, we demonstrate that WT1 is expressed in the early proepicardium, the epicardium and the subepicardial mesenchymal cells (SEMC). Lack of WT1 leads to severe defects in the epicardial layer and a concomitant absence of SEMCs, which explains the pericardial bleeding and subsequent embryonic death observed in Wt1 null embryos. We further show that a human-derived WT1 YAC construct is able to completely rescue heart defects, but only partially rescues defects in the urogenital system. Analysis of the observed hypoplastic kidneys demonstrate a continuous requirement for WT1 during nephrogenesis, in particular, in the formation of mature glomeruli. Finally, we show that the development of adrenal glands is also severely affected in partially ...
https://dev.biologists.org/content/126/9/1845?ijkey=5b2fb6b07f62a36b373bb346cc666269857b8ab2&keytype2=tf_ipsecsha
Epicardial-myocardial signaling directing coronary vasculogenesis.Epicardial-myocardial signaling directing coronary vasculogenesis.
Olivey H.E., Svensson E.C.. The establishment of the coronary circulation is critical for the development of the embryonic heart. Over the last several years, there has been tremendous progress in elucidating the pathways that control coronary development. Interestingly, many of the pathways that regulate the development of the coronary vasculature are distinct from those governing vasculogenesis in the rest of the embryo. It is becoming increasingly clear that coronary development depends on a complex communication between the epicardium, the subepicardial mesenchyme, and the myocardium mediated in part by secreted growth factors. This communication coordinates the growth of the myocardium with the formation of the coronary vasculature. This review summarizes our present understanding of the role of these growth factors in the regulation of coronary development. Continued progress in this field holds the potential to lead to novel therapeutics for the treatment of patients with coronary artery ...
http://www.uniprot.org/citations/20299672
Chapter 61. Pericardial Disease | Cardiac Surgery in the Adult, 4e | AccessSurgery | McGraw-Hill MedicalChapter 61. Pericardial Disease | Cardiac Surgery in the Adult, 4e | AccessSurgery | McGraw-Hill Medical
The pericardium envelops the heart and portions of the great vessels as a protective capsule. When incised longitudinally and transversely along the diaphragm it can be suspended from a chest retractor to present the heart for surgical procedures. The surgical importance of the pericardium stems from its involvement in alterations of cardiac filling. When the limited space between the noncompliant pericardium and heart acutely fills with blood or fluid, cardiac compression and tamponade may ensue. Constrictive disorders arise when inflammation and scarring cause the pericardium to shrink and densely adhere to the surface of the heart. This chapter discusses pericardial anatomy and function and describes the conditions that commonly give rise to the surgical problems of pericardial constriction and tamponade. The chapter also describes the diagnosis and therapy of these entities, the management of tamponade early and late after cardiac surgery, and the rationale for and against pericardial ...
http://accesssurgery.mhmedical.com/content.aspx?bookid=476§ionid=39679080
Human Anatomy - Lab 20 Step 3
Figure 20.2). The inner surface of the pericardial sac and the surface of the heart are covered by a serous membrane called the pericardium. It is a continuous membrane that forms a closed space called the pericardial cavity. Study the parts of the pericardium. The fibrous parietal pericardium [probe] is the rough outer layer of the pericardial sac. It is continuous with the external walls of the great vessels superiorly and blends with the fascia of the diaphragm inferiorly. ...
http://ect.downstate.edu/courseware/haonline/labs/L20/030100.htm
Journal of Clinical Imaging Science - A Rare Case of Primary Malignant Pericardial MesotheliomaJournal of Clinical Imaging Science - A Rare Case of Primary Malignant Pericardial Mesothelioma
Primary malignant pericardial mesothelioma (PMPM) is a rare tumor of the pericardium. The cause of this tumor is unknown and it has a very poor prognosis. Exposure to asbestos is correlated with the onset of pleural and peritoneal mesothelioma; however, the role of asbestos in pericardial mesothelioma is unclear. Here we highlight the radiological features of this rare tumor and its correlative pathological confirmation with the help of new immunohistochemical (IHC) markers.
https://clinicalimagingscience.org/a-rare-case-of-primary-malignant-pericardial-mesothelioma/
US9220824B2 - Implanting cardiac devices - Google Patents
A method of implanting a cardiac device featuring the insertion of an inner seal member through an opening in a pericardium about a living human heart. The inner seal member has a first sealing lip disposed inside the pericardium and surrounding an aperture through the inner seal member. An outer seal member is aligned with the inner seal member. The outer seal member has a second sealing lip disposed outside the pericardium, surrounding an aperture through the outer seal member. The inner seal member is secured to the outer seal member. The firsts sealing lip is engaged against an inner surface of the pericardium. The second sealing lip is engaged against an outer surface of the pericardium. A cardiac device is inserted into the pericardium through the apertures of the inner and outer seal members.
https://patents.google.com/patent/US9220824
Persistent primary coronary dilation induced by transatrial delivery of nitroglycerin into the pericardial space: a novel...Persistent primary coronary dilation induced by transatrial delivery of nitroglycerin into the pericardial space: a novel...
The sustained coronary vasodilator effect of intrapericardial delivery of nitroglycerin suggests that the drug is contained within the pericardial space, prolonging the time of action and exposure to perivascular tissue, and is not diffused rapidly into the systemic circulation. In contrast, intracoronary or intravenous administration of nitroglycerin is limited by a relatively short duration of action, with minimal or no organ selectivity, and is associated with systemic effects such as hypotension. These limitations may be particularly important when considering administration of vascular or myocardial growth factors, viral vectors or other proteins to induce angiogenesis or improve contractility, whose possible side effects include intimal hyperplasia, mitogenesis and systemic toxicity (12-15). For such agents, exposure to myocardial tissue needs to be maximized while minimizing availability to other organs. Lazarous and coworkers (16)demonstrated that intrapericardial administration of basic ...
http://www.onlinejacc.org/content/33/7/2073
Pericardium: operations and procedures - Hirslanden Private Hospital GroupPericardium: operations and procedures - Hirslanden Private Hospital Group
When and how is surgery performed on the pericardium? Find out more about the risks, complications, success rates and follow-up treatment involved in pericardium operations.
https://www.hirslanden.ch/en/corporate/treatments/pericardium-operations-procedures.html
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularizationThymosin beta4 induces adult epicardial progenitor mobilization and neovascularization
Cardiac failure has a principal underlying aetiology of ischaemic damage arising from vascular insufficiency. Molecules that regulate collateral growth in the ischaemic heart also regulate coronary vasculature formation during embryogenesis. Here we identify thymosin beta4 (Tbeta4) as essential for …
https://pubmed.ncbi.nlm.nih.gov/17108969/?dopt=Abstract
Regional electrophysiological effects of left ventricular hypertrophy in isolated rabbit hearts under normal and ischaemic...Regional electrophysiological effects of left ventricular hypertrophy in isolated rabbit hearts under normal and ischaemic...
Left ventricular hypertrophy (LVH) has been reported to produce differential electrophysiological effects in isolated epicardial and endocardial cells. This study aimed to examine regional electrophysiological effects of LVH in normal and ischaemic conditions in the whole heart. LVH was secondary to perinephritis-induced hypertension. Monophasic action potential duration (MAPD(90)), effective refractory period (ERP) and conduction delay were measured in paced, isolated working rabbit hearts either at one right ventricular and two left ventricular sites (apical and basal epicardium) or at three left ventricular sites (apical and basal epicardium, apical: endocardium). The hearts were subjected to 30 min of regional ischaemia and 15 min of reperfusion. In non-ischaemic conditions, LVH produced uniform prolongation of MAPD(90) and ERP in the left ventricular epicardium, but not in the endocardium. After coronary artery occlusion, LVH significantly increased ischaemia-induced transepicardial ...
https://strathprints.strath.ac.uk/30906/
Intracavitary mass as the initial manifestation of primary pericardial mesothelioma: a case reportIntracavitary mass as the initial manifestation of primary pericardial mesothelioma: a case report
A 31-year-old woman presented with a 3-month history of progressing fatigue and effort dyspnea. Echocardiography depicted a tumor within the free wall of the right ventricle and right atrium, located on both sides of the tricuspid annulus. Computed tomography showed disseminated circular shadows sized up to 7 mm-most likely metastatic lesions-in both lungs. The diagnosis of low-grade mesothelioma bifasicum was confirmed with histopathologic and immunohistochemical studies of the samples taken by thoracoscopy from parietal pleura, lung tumor, and diaphragm region. Chemotherapy, which included gemcitabine and carboplatin, resulted in transient improvement of the clinical status of the patient and reduction of the tumor mass lasting several months followed by progression of the disease. Significant amounts of pleural fluid and huge tumors within both pleural cavities emerged. The patient died due to respiratory and circulatory insufficiency 11 months following the diagnosis.. ...
http://www.mesothelioma-line.com/2007/05/15/intracavitary-mass-as-the-initial-manifestation-of-primary-pericardial-mesothelioma-a-case-report/
Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model (Basic...Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model (Basic...
ABSTRACT: BACKGROUND: Computational biology is a powerful tool for elucidating arrhythmogenic mechanisms at the cellular level, where complex interactions between ionic processes determine behavior. A novel theoretical model of the canine ventricular epicardial action potential and calcium cycling was developed and used to investigate ionic mechanisms underlying Ca2+ transient (CaT) and action potential duration (APD) rate dependence. METHODS AND RESULTS: The Ca2+/calmodulin-dependent protein kinase (CaMKII) regulatory pathway was integrated into the model, which included a novel Ca2+-release formulation, Ca2+ subspace, dynamic chloride handling, and formulations for major ion currents based on canine ventricular data. Decreasing pacing cycle length from 8000 to 300 ms shortened APD primarily because of I(Ca(L)) reduction, with additional contributions from I(to1), I(NaK), and late I(Na). CaT amplitude increased as cycle length decreased from 8000 to 500 ms. This positive rate-dependent property ...
https://models.cellml.org/exposure/f4b7120aa512c7f5e7a0664abcee3e8b/hund_rudy_2004_a.cellml/view
The SARD variety of multifractality of ventricular epicardial mapping during ischemia - CAMS Oxford Institute
We have analyzed cardiac ischemia-reperfusion in an animal model using epicardial electropotential mapping. We investigated the relationship between ischemia and variability of multifractality in epicardial electrograms. We present a new parameter called the singularity spectrum area reference dispersion (SARD) that clearly demonstrates the change in multifractility with the extent of myocardiaischemia. By contrasting the 3D ventricular epicardial SARD map with the activation map, we conclude that myocardial ischemia significantly influences the variety of multifractality of ventricular epicardium electrograms and the SARD parameter is useful in correlating multifractality of epicardial electrograms with location of ischemia closely. © Science in China Press 2006.
https://www.camsoxford.ox.ac.uk/coi-publications/publications/106768
THE PERICARDIUM GUARDIAN OF THE SECRET OF OUR DIVINITY | bioenergetic osteopathyTHE PERICARDIUM GUARDIAN OF THE SECRET OF OUR DIVINITY | bioenergetic osteopathy
I am pure Life Energy, experiencing matter on Earth, in this body called Montserrat.. How did I become involved with the Pericardium?. Since I was little, I always wanted to understand the meaning of what we refer to as just life (well, thats just life…). To get a better picture, I studied extensively. I attended teaching college, completed nursing studies, studied four years of medicine, taught Morphopsychology, Neurology and Osteopathy and gained more than 30 years of experience in hospitals in different countries throughout the world. More importantly, I have lived to the full, passionately experiencing each stage of my life in a quest to understand its deeper meaning, to understand the deeper meaning of each learning stage. My children Oriol, Marc and Nina have been and still are, lights on my path that have enabled me to see my noblesse in their eyes, my dis-ease in their sicknesses, my freedom in their smiles, my responsibility in their autonomy and my lightness of being in their ...
http://www.vivalavida.org/en/publications/2012/the-pericardium-guardian-of-the-secret-of-our-divinity
Brugada syndrome: 1992-2002 | JACC: Journal of the American College of CardiologyBrugada syndrome: 1992-2002 | JACC: Journal of the American College of Cardiology
The cellular mechanisms believed to underlie Brugada syndrome evolved on a parallel but separate track from that of the clinical syndrome. The concepts of all-or-none repolarization of the ventricular epicardial action potential and of phase 2 reentry were developed in the early 1990s (25-27). It was on a bus ride to the airport following a meeting of the International Society of Computerized Electrocardiography (ISCE) in Florida that Dr. Antzelevitch, fortuitously seated next to Dr. Phillipe Coumel, expressed surprise that there was apparently no clinical counterpart to phase 2 reentry as a mechanism of arrhythmogenesis. After some discussion, Dr. Coumel suggested that Dr. Antzelevitch contact the Brugada brothers, who had recently described a syndrome with somewhat similar characteristics. The rest, as they say, is history. Drs. Antzelevitch, Pedro, Josep, and Ramon Brugada, Jeffrey Towbin, and Kolawanee Nademanee have worked as a cohesive team since the mid 1990s.. Basic studies conducted ...
http://www.onlinejacc.org/content/41/10/1665
Majesky Laboratory Current Research | Seattle Childrens HospitalMajesky Laboratory Current Research | Seattle Childrens Hospital
The vascular system consists of networks of blood and lymphatic vessels that interact with their target tissues in intricate and often surprising ways. The Majesky Laboratory uses molecular biological and developmental genetic approaches to address fundamental questions in development and differentiation of blood vessels.. We currently have two major areas of research focus. One concerns the molecular mechanisms that control formation and differentiation of coronary vessels during heart development. The other is on vascular stem and progenitor cells that reside in the adventitial layer of artery wall.. Developmental fate mapping studies show that progenitor cells in the proepicardium (PE) give rise to coronary vessels. Formation of coronary vessels occurs by an epithelial to mesenchymal transition (EMT) of epicardial cells followed by vasculogenesis in the subepicardial space, assembly and remodeling of a primitive coronary plexus, and investment by pericytes and coronary smooth muscle cells ...
http://www.seattlechildrens.org/research/developmental-biology-regenerative-medicine/majesky-lab/research/
Searching for mitogenic factors from the epicardium: PDGFA, Igf2 and more :: University of Southern California Dissertations...
Mammalian cardiomyocytes undergo cell division only during embryonic development. This process can be disturbed by many gene mutations, resulting in myocardial hypoplasia Retinoic acid (RA), the biologically active derivative of vitamin A, is an important morphogen during development. Deficiency in vitamin A by dietary deprivation and mutation in Rxra, a nuclear receptor for retinoic acid, will lead to embryonic myocardial hypoplasia. It has been demonstrated that Rxra acts in the epicardium, a thin layer of cells enveloping the myocardium, to influence myocardium proliferation. Previous studies suggested that RXRA induces the secretion of mitogenic factors from the epicardium. In this study, we found that AGN193109, an RA antagonist, and retinoic acid have no effect on the production of mitogenic activity from a rat epicardial cell line, EMC, a mouse epicardial cell line, MEC1, or primary epicardial cells from chick embryos. Rxra knockdown via adenovirus-mediated RNAi does not reduce the ...
http://digitallibrary.usc.edu/cdm/compoundobject/collection/p15799coll127/id/527322/rec/19
Download Cardiac Nursing (6th Edition) by Susan L. Woods, Erika S. Sivarajan Froelicher, Sandra PDF - Gomad Festival BooksDownload Cardiac Nursing (6th Edition) by Susan L. Woods, Erika S. Sivarajan Froelicher, Sandra PDF - Gomad Festival Books
The main function of the pericardium and its fluid is to lubricate the moving surfaces of the heart. The pericardium also helps to retard ventricular dilation, helps to hold the heart in position, and forms a barrier to the spread of infections and neoplasia. Pathophysiological conditions such as cardiac bleeding or an exudate-producing pericarditis may lead to a sudden or large accumulation of fluid within the pericardial sac. This may impede ventricular filling. From 50 to 300 mL of pericardial fluid may accumulate without serious ventricular impairment. Qxd 6 11/21/11 PA R T I 10:30 AM Page 6 / Anatomy and Physiology in an anterior, leftward, and inferior direction. Blood flows out of the ventricle from the apex toward the aorta in a superior and rightward direction (Fig. 1-8). Thus, blood flows from posterior orifices into both ventricles in a leftward direction and is ejected superiorly toward the center of the heart. The right ventricular outflow tract is more tubular; the left ventricular ...
http://gomadfestival.com/library/cardiac-nursing-6-th-edition
Digital Public defence: Mona Svanteson - Institute of Clinical MedicineDigital Public defence: Mona Svanteson - Institute of Clinical Medicine
Coronary CT angiography (CCTA) is an established method for ruling out coronary artery stenoses in symptomatic patients with low to intermediate risk for cardiovascular events. Patients with inflammatory joint diseases and type 1 diabetes have an increased risk for coronary events, but cardiovascular disease prevention is clinically challenging as chest pain often may be absent or unspecific in these patients.. The overall aim of the thesis was to evaluate the prevalence and characteristics of CCTA-verified plaques in patients with inflammatory joint diseases and type 1 diabetes, and further to assess associations between CCTA findings and clinical variables. Additionally, the long-term effect of statins on plaque morphology was evaluated in the patients with inflammatory joint diseases, and the associations between coronary atherosclerosis and epicardial adipose tissue were assessed in the patients with type 1 diabetes.. This thesis shows a high prevalence of coronary plaques in both cohorts. ...
https://www.med.uio.no/klinmed/english/research/news-and-events/events/disputations/2020/svanteson-mona.html
JP Sapporo Yokota T - Bioblast
Nakajima T, Yokota T, Shingu Y, Yamada A, Iba Y, Ujihira K, Wakasa S, Ooka T, Takada S, Shirakawa R, Katayama T, Furihata T, Fukushima A, Matsuoka R, Nishihara H, Dela F, Nakanishi K, Matsui Y, Kinugawa S (2019) Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis. Sci Rep 9:3535 ...
https://www.mitophysiology.org/index.php/JP_Sapporo_Yokota_T
im so sleepy: February 2008im so sleepy: February 2008
The problem they have here is now they have a hole in the heart and it starts to bleed. That in and of itself isnt great, but the main problem is that the heart sits in a little sac of tissue called the pericardium (literally around the heart). Once its full of blood, if you have continued bleeding it starts to compress the heart and the compressed heart can no longer fill and pump blood. This causes low blood pressure and eventally cardiac arrest. This is called cardiac tamponade. The way to fix this is to open up the pericardial sac and let the blood from around the heart out, then it can again fill and pump blood. The problem with this is that you still have bleeding and now its not just limited to the pericardium, but can continue to bleed ...
http://laryngoscope.blogspot.com/2008_02_01_archive.html
Patent US7515969 - Sensor guided epicardial lead - Google PatentsPatent US7515969 - Sensor guided epicardial lead - Google Patents
Implantable cardiac monitoring and stimulation methods and devices with epicardial leads having sensor feedback. A fixed or extendable/retractable sensor may be displaceable within the leads lumen and configured to sense the presence of an anatomical feature or physiological parameter of cardiac tissue in proximity with the lead bodys distal end. The sensor may include an ultrasonic sensing element, a perfusion sensor, a photoplethysmographic sensor, or a blood oximetry sensor. Methods of determining suitability for implanting a lead involve the steps of accessing an epicardial surface of the heart, and moving the cardiac lead to an implant site at the epicardial surface. A transmitted signal is directed at the implant site. A reflected signal is received, indicative of the presence of a blood vessel at the implant site. A determination may be made to determine whether the implant site is suitable or unsuitable based on the reflected signal.
http://www.google.ca/patents/US7515969
Cardiac MetastasesCardiac Metastases
The specimen is of a markedly enlarged, pale heart with some subepicardial blood-staining and nodularity. The paleness and increase in size of heart is mostly due to increase in epicardial fat. Externally the region of the right ventricle is distorted and posteriorly there is narrowing of the right ventricular cavity. Again, posteriorly, the left ventricle has been sectioned and white tumour tissue may be seen invading the epicardial fat. There is associated patchy haemorrhage. Tumour tissue can also be seen in the myocardium. Although this specimen is not very satisfactory from the demonstration point of view, it shows secondary anaplastic carcinoma of the pericardium and myocardium. The origin of the carcinoma is unknown. ...
https://www.monash.edu/museumofpathology/cardiovascular-system/cardiac-metastases
Internet Help in Biochemistry and Biology
On the internet Process help provides information about the work and structure of center which is very important in biochemistry. Learners can understand better through online Process help the value of center.. Study of center and its function:. In your personal program, the center is usually in the center of the thorax. The center is usually thought to be on the staying aspect because the staying center i.e., staying ventricle is more highly effective it forces program to all places of the personal body system. The center is fed by the coronary activity and is covered by a sac known as pericardium. The pericardium contains two places the pericardium -made of hefty sailing floating fibrous structures and a twice structure - containing a serous fluid to decrease massaging during center contractions.. The top is the boring point situated in an ineffective route. Stethoscope can be straight placed over the top, so that the exceeds can be described. In regular grownups the huge of the center ...
http://sciencenewsarticles.org/1360265/internet-help-in-biochemistry-and-biology/
α4β1- and α6β1-integrins are functional receptors for midkine, a heparin-binding growth factor | Journal of Cell Scienceα4β1- and α6β1-integrins are functional receptors for midkine, a heparin-binding growth factor | Journal of Cell Science
We have provided evidence that MK specifically binds to α4β1- and α6β1-integrins. The ligands of α4β1-integrin are fibronectin, a major component of the ECM, and VCAM, a member of the immunoglobulin superfamily. α4β1-Integrin recognizes LDV in the alternatively spliced III CS domain of fibronectin (Guan and Hynes, 1990; Kleiman and Mosher, 2002). α4β1-Integrin plays important roles in cell migration - it governs lymphocyte migration (Rose et al., 2001), is involved in recruitment of neutrophils to inflammatory sites (Burns et al., 2001; Henderson et al., 2001) and is essential for the migration of epicardial progenitor cells to the surface of the heart to form the epicardium (Sengbusch et al., 2002). MK also promotes the migration of neutrophils, macrophages, UMR-106 osteoblastic cells and neurons (Takada et al., 1997; Maeda et al., 1999; Horiba et al., 2000; Qi et al., 2001). Therefore, we postulated that MK-induced migration of UMR-106 cells might be mediated by α4β1-integrin. ...
http://jcs.biologists.org/content/117/22/5405
physiology - Why is pericardium muscle repolarizated earlier than endocardium? - Biology Stack Exchangephysiology - Why is pericardium muscle repolarizated earlier than endocardium? - Biology Stack Exchange
Im just going to link you to another post here, which I believe answers the same question. Its because the facilitation of the transient outward current if much more prominent in epicardial regions than in endocardial regions.. And the following citation, Transient outward potassium current, Ito, phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms, provides some mechanistic insight.. To answer the rest of the question:. So in an ECG you have leads that record whether a charge is moving toward, or away from the lead. These net charges are reflected on the ECG as either positive or negative deflections. You have a signal from the sinoatrial node that causes a depolarization in the right atrium, then the left atrium (biphasic p wave). In each case, however, we see the positive p wave because in this depolarization the net charge is moving toward the electrodes. Studies on atrial repolarization note that yes, the atrial repolarization is ...
https://biology.stackexchange.com/questions/28509/why-is-pericardium-muscle-repolarizated-earlier-than-endocardium
Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial...Left ventricular rotational mechanics in patients with coronary artery disease: differences in subendocardial and subepicardial...
Results Compared with normal subjects, peak subendocardial LV twist was significantly impaired in patients with STEMI (11.2±6.0° vs 15.3±2.7°, p,0.001). In patients with chronic HF, peak subendocardial LV twist was even more impaired (4.6±3.4°, p,0.001 vs normal subjects and patients with STEMI). Conversely, peak subepicardial LV twist was not statistically different between normal subjects and patients with STEMI (8.9±1.9° vs 8.4±4.4°, p=0.98), whereas it was significantly impaired in patients with chronic HF (2.6±2.5°, p,0.001 vs normal subjects and patients with STEMI). Peak subendocardial LV twist was not statistically different between large and small STEMI, whereas peak subepicardial LV twist was significantly lower in large STEMI than in small STEMI (7.1±4.8° vs 9.6±3.6°, p=0.025). ...
http://heart.bmj.com/content/96/21/1737
Responses and afferent pathways of superficial and deeper C|sub|1|/sub|-C|sub|2|/sub| spinal cells to intrapericardial...Responses and afferent pathways of superficial and deeper C|sub|1|/sub|-C|sub|2|/sub| spinal cells to intrapericardial...
Fingerprint Dive into the research topics of Responses and afferent pathways of superficial and deeper C,sub,1,/sub,-C,sub,2,/sub, spinal cells to intrapericardial algogenic chemicals in rats. Together they form a unique fingerprint. ...
https://scholars.okstate.edu/en/publications/responses-and-afferent-pathways-of-superficial-and-deeper-csub1su/fingerprints/
Diseases of the Myocardium, Pericardium, and Endocardium | SpringerLinkDiseases of the Myocardium, Pericardium, and Endocardium | SpringerLink
Cardiomyopathies are disorders of the myocardium of unknown cause that are not associated with other disorders (figure 9-1). Specific heart muscle diseases, once known as secondary cardiomyopathies,...
https://link.springer.com/chapter/10.1007/978-1-4757-1815-7_9
Torso mapping can identify changes in ventricular activation-recovery intervals during regional ischaemia that are not detected...
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https://www.neuroscience.ox.ac.uk/publications/106686
Canine Pericardial Disease -heart disease in dogsCanine Pericardial Disease -heart disease in dogs
The Pericardium is a crucial muscular part of the heart, resulting in heart disease and even failure if it works improperly. Most common symptom is rapid distention of the abdomen. Rapid treatment is required and includes surgery.
https://pethealthnetwork.com/dog-health/dog-diseases-conditions-a-z/pericardial-disease-dogs
Data CollectionData Collection
Tissue and Eye banks across Australia provide data for cardiovascular, musculoskeletal, skin tissue and amnion donations.. Musculoskeletal donations can be in the form of bone, tendon and ligaments and are utilised for knee and hip replacements, reconstructive orthopaedic surgery following trauma or disease and spinal deformities and can aid in prevention of limb loss following tumour removal. Just one musculoskeletal donation can aid many recipients and greatly improve their quality of life.. Cardiovascular tissue incorporates donations of heart valves, pericardium and thoracic aorta. Heart valves are necessary to regulate the flow of blood to and from the heart, whereas pericardium can be used during neurosurgery or, like the thoracic aorta, can also be used for vascular repair of defects or injury.. Donated skin contributes to saving lives and improving long term outcomes for patients who suffer severe burns. Donated skin is essential when a patients own skin cannot be used for grafting. ...
https://www.anzdata.org.au/anzetd/data-collection/
SCMR Newsletter - December 2017SCMR Newsletter - December 2017
Clinical History: A 71-year-old male with a previous history of working-exposure to glass components was admitted to our hospital with persistent complaints of chest tightness, shortness of breath and edema in the lower limbs that started 3 months prior to his admission. An echocardiogram from a local hospital identified a nodule on the right-sided of the pericardium and large pericardial and pleural effusions. Percutaneous drainage was performed and 30 mL were obtained from the pericardium and 500 mL from the pleurae, both of hemorrhagic appearance. Biochemical analysis of pericardial and pleural fluids was not performed and cytological analysis was negative for malignant cells. Medical treatment was initiated and the patient remained asymptomatic for the following 3 days. The patients symptoms recurred and rapidly worsened so he was admitted to our institution for further examination and treatment. ...
http://myemail.constantcontact.com/SCMR-Newsletter---December-2017.html?soid=1102224460072&aid=BuhMUpalQ34
ICD-10 Diagnosis Code I31.8 Other specified diseases of pericardiumICD-10 Diagnosis Code I31.8 Other specified diseases of pericardium
Diagnosis Code I31.8 information, including descriptions, synonyms, code edits, diagnostic related groups, ICD-9 conversion and references to the diseases index.
https://icdlist.com/icd-10/i318
About - Brittany AlsotAbout - Brittany Alsot
Film instructs at the speed of thought with the language of dreams. Too often forgotten in this equation is the heart. The pericardium protects the heart, deciding what goes in or out of the vital organ. Films can heal when people see themselves and their experiences on screen. Our society heals when stories teach empathy and we leave the theater with a little more understanding and perspective. This sounds lofty, but I believe in the impact of showing up with integrity and respect for the people and stories that move the needle towards love. Pericardium Productions aims to accomplish this by conscientiously representing people of color, queer folks, and other marginalized communities.. As of December 2016, we have two dramatic shorts on the festival circuit:. ...
http://brittanyalsot.com/about/
Category: Pericardium - Guru Acupuncture & Alternative Medicine
How to maintain good health without taking medicine.Generally in all families one of the member is affected by any one of the disease and taking treatment and medications. Many of the illness we face because of no walking , no exercise, no water, no proper diet in proper time. Not Drinking sufficient water, no proper sleeping habits in time, and unnecessary stress ...
http://guruaam.com/blog/category/pericardium
PericardiumPericardium
The fibrous pericardium is the outside layer of the pericardium, made up of dense and loose connective tissue. While capable of ... The serous pericardium, in turn, is divided into two parts: The parietal serous pericardium, which lines the interior side of ... The visceral serous pericardium extends to the root of the great vessels and joins the parietal serous pericardium at the ... The right phrenic nerve passes to the right of the pericardium. The left phrenic nerve passes over the pericardium of the left ...
https://en.wikipedia.org/wiki/Pericardium
Pericardium (Chinese medicine)Pericardium (Chinese medicine)
The Pericardium has a meridian named for it, which reflects the health of the organ. In terms of the Five Elements, these ... In general theory, the Pericardium is not distinguished from the Heart. It is also the first line of defence against the Heart ... See Zang Fu theory.) The Pericardium is also called the "heart protector", and, for clinical purposes, is considered a yin ... According to traditional Chinese medicine, it is often best to approach the treatment of heart problems via the Pericardium, ...
https://en.wikipedia.org/wiki/Pericardium_(Chinese_medicine)
Glossary of gastropod termsGlossary of gastropod terms
Pericardium. The chamber containing the heart. Periostracum. The epidermal covering of some shells. Pervious. Very narrowly ...
https://en.wikipedia.org/wiki/Glossary_of_gastropod_terms
Shalwar kameezShalwar kameez
... pericardium; a galloping horse that shakes its rider." According to Platt's A Dictionary of Urdu, Classical Hindi, and English ...
https://en.wikipedia.org/wiki/Shalwar_kameez
Norman CheversNorman Chevers
The Pericardium. Springer Science & Business Media. p. 191. ISBN 978-1-4419-9137-9. "Chevers, Norman - Biographical entry - ...
https://en.wikipedia.org/wiki/Norman_Chevers
Fredrick Arthur WilliusFredrick Arthur Willius
Calcification of Pericardium. Arch Intern Med (Chic). 1932;50(2):184-191. ---. Pericarditis: III. Pericarditis with Effusion. ...
https://en.wikipedia.org/wiki/Fredrick_Arthur_Willius
MediastinumMediastinum
... the anterior mediastinum being in front of the pericardium, the middle mediastinum contains the pericardium and its contents, ... Anterior mediastinum Is bounded: laterally by the pleurae; posteriorly by the pericardium; anteriorly by the sternum , the left ... Thoracic Wall, Pleura, and Pericardium - Dissector Answers Archived 2012-09-01 at the Wayback Machine "Cell Biology and Anatomy ... This lower part is subdivided into three regions, all relative to the pericardium - ...
https://en.wikipedia.org/wiki/Mediastinum
José L. DuomarcoJosé L. Duomarco
Functions for the Pericardium. J.L. Duomarco; C.E. Giambruno; R. Rimini; Cardiovascular Functions Ed. A. A. Luisada McGraw Hill ... Cardiac retropulsion and zonal pressure of the pericardium. J.L. Duomarco; R. Rimini C.E. Giambruno Acta Physiologica Latino ...
https://en.wikipedia.org/wiki/José_L._Duomarco
Orang-Outang, sive Homo SylvestrisOrang-Outang, sive Homo Sylvestris
Pericardium attached to diaphragm. More rounded apex of the heart. No pouches in the chaps (unclear). Much larger brain than in ...
https://en.wikipedia.org/wiki/Orang-Outang,_sive_Homo_Sylvestris
Hyalinobatrachium pallidumHyalinobatrachium pallidum
The pericardium is light golden. Many individuals from the Sierra de Perijá have a number of irregular black flecks on the ...
https://en.wikipedia.org/wiki/Hyalinobatrachium_pallidum
Hammans signHamman's sign
Hamman's syndrome Shabetai, Ralph (2003-10-31). The Pericardium - Google Book Search. ISBN 9781402076398. Retrieved 2008-11-26 ...
https://en.wikipedia.org/wiki/Hamman's_sign
Anatomy of the human heartAnatomy of the human heart
The pericardium is a thick membrane that covers the heart. It consists of two layers: the fibrous pericardium and the serous ... The serous pericardium is thin and covers the heart. It is also called the epicardium. The fibrous pericardium is much thicker ... pericardium. It forms two recesses: the transverse recess and oblique recess. The transverse recess lies behind the aorta and ...
https://en.wikipedia.org/wiki/Anatomy_of_the_human_heart
Kidney (Chinese medicine)Kidney (Chinese medicine)
The other Yin, or Zang, organs are the lungs (Fei), liver (Gan), spleen (Pi), and heart (Xin). Sometimes the pericardium (Xin ...
https://en.wikipedia.org/wiki/Kidney_(Chinese_medicine)
Conjoined twinsConjoined twins
Conjoined by their sternum, pericardium, and liver. In 2014, they were separated in Shanghai, China, at the Shanghai Children's ...
https://en.wikipedia.org/wiki/Conjoined_twins
Obstructive shockObstructive shock
Inflammation of the pericardium is called pericarditis. This is caused by infection, renal failure or autoimmune disease. ... When fluid collects slowly, the pericardium can stretch. Thus, a chronic effusion can be as large as 1 liter. Acute effusions ... Trauma can cause blood to fill the pericardium. Cancer can also cause effusions. Whether an effusion causes tamponade depends ...
https://en.wikipedia.org/wiki/Obstructive_shock
Human bodyHuman body
It is surrounded by the pericardium which holds it in place in the mediastinum and serves to protect it from blunt trauma, ... Jaworska-Wilczynska, Maria; Trzaskoma, Pawel; Szczepankiewicz, Andrzej A.; Hryniewiecki, Tomasz (2016). "Pericardium: structure ...
https://en.wikipedia.org/wiki/Human_body
John Ware (physician)John Ware (physician)
1833). "Rupture of the Aorta within the Pericardium". The Boston Medical and Surgical Journal. 8 (7): 103-105. doi:10.1056/ ...
https://en.wikipedia.org/wiki/John_Ware_(physician)
Alfred George BarrsAlfred George Barrs
His doctoral thesis On adherent pericardium of rheumatic origin, with cases was written in 1883. Barrs was married to Alice ... George, Barrs, Alfred (1883). "On adherent pericardium of rheumatic origin: with cases". hdl:1842/23706. {{cite journal}}: Cite ...
https://en.wikipedia.org/wiki/Alfred_George_Barrs
Uremic pericarditisUremic pericarditis
The pericardium is infiltrated by the fibrinous exudate. This consists of fibrin strands and leukocytes. Fibrin describes an ...
https://en.wikipedia.org/wiki/Uremic_pericarditis
PericarditisPericarditis
Late gadolinium contrast will show uptake of contrast by the inflamed pericardium. Normal pericardium will not show any ... Surgical removal of the pericardium, pericardiectomy, may be used in severe cases and where the pericarditis is causing ... Pericarditis is inflammation of the pericardium, the fibrous sac surrounding the heart. Symptoms typically include sudden onset ... EKG or Holter monitor will then depict electrical alternans indicating wobbling of the heart in the fluid filled pericardium, ...
https://en.wikipedia.org/wiki/Pericarditis
Pulmonary veinPulmonary vein
ISBN 978-0-443-06612-2. Skandalakis, editor in chief John E. (2004). "Chapter 7. Pericardium, Heart, and Great Vessels in the ...
https://en.wikipedia.org/wiki/Pulmonary_vein
Jean-Baptiste DumanginJean-Baptiste Dumangin
The pericardium contained the usual amount of serosity; the heart was pale, but in its natural state. The brain and its ... The lungs adhered to the entire surface of the pleura, diaphragm and pericardium. Their substance was healthy and free of ...
https://en.wikipedia.org/wiki/Jean-Baptiste_Dumangin
Mary Jane KellyMary Jane Kelly
The pericardium was open below and the heart absent. In the abdominal cavity, there was some partly digested food of fish and ...
https://en.wikipedia.org/wiki/Mary_Jane_Kelly
Asterophila japonicaAsterophila japonica
However this larva has a pericardium and a kidney. Randall & Heath, 1912. Warén A. & Lewis L.M. (1994) Tho new species of ...
https://en.wikipedia.org/wiki/Asterophila_japonica
Heart developmentHeart development
Mesothelial pericardium forms the outer lining of the heart. The inner lining of the heart - the endocardium, lymphatic and ... Then mesothelial cells form the pericardium and migrate to form most of the epicardium. Then the heart tube is formed by the ...
https://en.wikipedia.org/wiki/Heart_development
William PasteurWilliam Pasteur
with Solomon Solis-Cohen: "Spontaneous pneumothorax and pneumo-pericardium". The American Journal of the Medical Sciences. ...
https://en.wikipedia.org/wiki/William_Pasteur
Marstonia comalensisMarstonia comalensis
Ctenidium is positioned a little in front of pericardium. There are 24-25 ctenidial filaments, that are broadly triangular with ...
https://en.wikipedia.org/wiki/Marstonia_comalensis
Ernst KlimtErnst Klimt
He died unexpectedly, from an inflammation of the pericardium. Gustav took care of his wife and daughter and completed his ...
https://en.wikipedia.org/wiki/Ernst_Klimt
HeartHeart
The pericardium is the sac that surrounds the heart. The tough outer surface of the pericardium is called the fibrous membrane ... while the part of the serous membrane attached to the heart is known as the visceral pericardium. The pericardium is present in ... The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of the heart ... Between the third and fourth week, the heart tube lengthens, and begins to fold to form an S-shape within the pericardium. This ...
https://en.wikipedia.org/wiki/Heart
SarcoidosisSarcoidosis
Nevertheless, the involvement of pericardium and heart valves are uncommon. The frequency of cardiac involvement varies and is ...
https://en.wikipedia.org/wiki/Sarcoidosis
Pericardium: MedlinePlus Medical Encyclopedia ImagePericardium: MedlinePlus Medical Encyclopedia Image
The pericardium is a thin double-layered sac which encloses the heart. Fluid is contained within the layers and lubricates the ... The pericardium is a thin double-layered sac which encloses the heart. Fluid is contained within the layers and lubricates the ...
https://medlineplus.gov/ency/imagepages/18081.htm
MAUDE Adverse Event Report: TUTOGEN MEDICAL, GMBH TUTOMESH® BOVINE PERICARDIUM MEMBRANE
Rti surgical, inc (rti) and tutogen medical gmbh (tmi), a wholly subsidiary of rti, received a complaint on (b)(6) 2020. An adverse event was reported through a post market survey for tutomesh® for breast reconstruction application via qualtrics survey software. The doctor indicated that in her experience using the product, 5-10% of the cases/patients have experienced post-operative development of seroma, 1-5% of the cases/patients have experienced capsular contraction, and 1-5% have experienced adhesions. To date, no additional information has been provided ...
https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfmaude/detail.cfm?mdrfoi__id=9836653&pc=FTM
pericardium Archives - The Rojak Potpericardium Archives - The Rojak Pot
The Internet is full of weirdness. Here is one of them - a human body energy clock. It advises you on what to do at any particular time in a day. Apparently, different organs of your body are activate ... ...
https://www.rojakpot.com/tag/pericardium/
The heart and pericardium | HSTalksThe heart and pericardium | HSTalks
Thomas R. Gest on The heart and pericardium, part of a collection of multimedia lectures. ... The heart and pericardium. Im Thomas Gest and Im professor of anatomy at Central Michigan University College of Medicine. ... The heart and pericardium. *Prof. Thomas R. Gest - University of Houston College of Medicine, USA ... Gest, T.R. (2021, June 29). The heart and pericardium [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart ...
https://hstalks.com/t/4650/the-heart-and-pericardium/?biosci
What is the pericardium made of?What is the pericardium made of?
The pericardium consists of two layers: the fibrous and the serous.. Where is pericardium found?. What is the pericardium? The ... The word "pericardium" means around the heart. The outer layer of the pericardium is called the parietal pericardium. The inner ... The parietal and visceral pericardia together form the serous pericardium.. What are the 2 layers of the serous pericardium?. ... It can be divided into three layers, the fibrous pericardium, the parietal pericardium, and the visceral pericardium. ...
https://www.onteenstoday.com/various-essays/what-is-the-pericardium-made-of/
Pericardium - Humpath.com - Human pathology
Diseases of the pericardium: morphologic study of surgical specimens from 35 patients. Mambo NC. Hum Pathol. 1981 Nov;12(11): ... pericardium 18 March 2007 Adj. pericardial Pathology pericardial anomalies pericardial malformations pericardial lesions ... Pericardium. * purulent pericarditis 2 January 2017 Images purulent pericarditis Images : https://twitter.com/laherbefolle/ ... Home , E. Pathology by systems , Cardiovascular system , Heart , Pericardium. ...
http://www.humpath.com/spip.php?rubrique384
Partial absence of the pericardium: Only an incidental finding? | Anales de PediatríaPartial absence of the pericardium: Only an incidental finding? | Anales de Pediatría
Absence of the pericardium (AoP) is a rare anomaly usually detected by chance. Its incidence is less than 1 case per 10 000 ... Partial absence of the pericardium: Only an incidental finding? Ausencia parcial de pericardio: ¿únicamente un hallazgo ... Quantitative criteria for the diagnosis of the congenital absence of pericardium by cardiac magnetic resonance. ... 01 June 2022 Partial absence of the pericardium: Only an incidental finding? ...
https://analesdepediatria.org/en-partial-absence-pericardium-only-an-articulo-S2341287922000874
PericardiumPericardium
Never Fall In Love Always Rise In Love, Never Say We Fell In Love, Always Say We Feel The Love." Get Latest Shayari, Video Status, Quotes & Holidays Wishes ©2022 ...
https://www.lovesove.com/pericardium/
pericardium (parietal serous, anatomy) - General Practice notebookpericardium (parietal serous, anatomy) - General Practice notebook
pericardium (parietal serous, anatomy) Last reviewed 01/2018. The parietal layer of serous pericardium is a mesothelial layer ... Also, the parietal paricardium is continuous with the visceral pericardium across the points at which the great vessels ... of cells which lines the inner layer of the fibrous pericardium. Amorphous connective tissue separates the two layers. ...
https://gpnotebook.com/simplepage.cfm?ID=-1053491141
Adherent PericardiumAdherent Pericardium
The number of cases of adherent pericardium seen in the post-mortem room, and the comparatively few cases in which a diagnosis ... in no fewer than thirty-one was adherent pericardium found at the autopsy - in the majority of cases, viz. Twenty-one, as a ...
https://www.forgottenbooks.com/fr/books/AdherentPericardium_10275434
15 - Pericardium & Heart.ppt - Español15 - Pericardium & Heart.ppt - Español
15 - Pericardium & Heart.ppt * 1. SEMINAR -BY MORESHWAR PAWAR AND LUBAINA RAMPURAWALA ... acts as a double pump Conical in shape Slightly larger than the clenched fist Lies free within the pericardium Connected ...
https://es.slideshare.net/MoreshwarPawar1/15-pericardium-heartppt?next_slideshow=true
New publication: Equine pericardium: a versatile alternative … - Auto Tissue BerlinNew publication: Equine pericardium: a versatile alternative … - Auto Tissue Berlin
Equine pericardium was used in 58 patients and bovine pericardium was used in 53 patients. Recorded variables included ... New publication: Equine pericardium: a versatile alternative …. Date: April 23, 2021. The group around Dr. Osman Al-Radi from ... Conclusions: Equine pericardium is a safe patch material for reconstruction in congenital heart surgery. It may be preferable ... The aim of this study was to describe our initial experience with the use of equine pericardium and its safety and advantages ...
https://autotissue.de/2021-04-elassal/
IMSEAR at SEARO: Congenital asymptomatic absence of pericardium.
An interesting congenital anomaly of the pericardium is its absence. One such case is reported here. Recent literature is ... Sivaprasad M, Iyer KS, Venugopal P. Congenital asymptomatic absence of pericardium. The Indian Journal of Chest Diseases & ...
https://imsear.searo.who.int/handle/123456789/29855?locale=fr
Pericardium - Ergopathics CanadaPericardium - Ergopathics Canada
Note: These vials are not intended for diagnosing or treatment.
https://ergopathics.ca/products/pericardium
COMING SOON: PERICARDIUM] | MSCIACOMING SOON: PERICARDIUM] | MSCIA
Hello MSCIAers!. Cardiac attack being one of the most deadly disease in Indonesia. But not everyone know about cardiac attack and how to manage it. To learn more about cardiac attack, DOME (Departement of Medical Education) will have project about cardiac attack with the specialist and CPR skill.. Come and join with us ...
https://mscia.org/coming-soon-pericardium/
Echocardiography online, the pericardiumEchocardiography online, the pericardium
Transthoracic Pericardium *TT Pericardial Effusion, Localized, Right ventricle. *TT Pericardial Constriction and Atrial ... Transthoracic Pericardium *TT Pericardial Effusion, Localized, Right ventricle. *TT Pericardial Constriction and Atrial ...
https://echobyweb.com/homepage/class/pericardial-physiology-and-pathology/7/
ChillSpot1 - Bovine Pericardium TissueChillSpot1 - Bovine Pericardium Tissue
Driven by a desire to serve patients, the company works with the worlds top clinicians and researchers to address unmet healthcare needs. The Bridgemed team can handle the fatigue and structural testing of transcatheter heart valve frames. https://www.bridgemedsolutions.com/tissue/ - ChillSpot1 is a Top Social Network Site. Earn Tips and monetize your channel instantly! Upload videos, photos, songs, pics and more. Best profile design. Build followers/subscribers/friends/groups or join the Chat Rooms to connect with friends. ChillSpot1 is available worldwide and all are welcome to join. ChillSpot1 supports free speech. Promote yourself and have your voice heard. Be sure to stop by the chat rooms too. On ChillSpot1 you have it all.
https://chillspot1.com/photo/U9GGWB8SKR7M
Pericardium - Intelligent Ultrasound - eLearningPericardium - Intelligent Ultrasound - eLearning
ISO 13485 Certified. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. ...
https://academy.intelligentultrasound.com/lesson/pericardium/
pericardium - kaya vs. the world
pericardium when the lungs collapsed. I broke the rip cage open. and set the black smoke. free from the bronchioles ... is where finger pads met pericardium. tapped the membrane. to the echo of the heart. and ripped it out ...
https://kayavstheworld.com/2015/12/17/pericardium/
Malignant Mesothelioma Mortality in Women - United States, 1999-2020 | MMWRMalignant Mesothelioma Mortality in Women - United States, 1999-2020 | MMWR
ICD-10 codes C45.0 (mesothelioma of pleura), C45.1 (mesothelioma of peritoneum), C45.2 (mesothelioma of pericardium), C45.7 ( ... Mesothelioma deaths were classified as mesothelioma of pleura (968; 7.9%), peritoneum (1,119; 9.2%), pericardium (35; 0.3%), ... mesothelioma of pericardium), C45.7 (mesothelioma of other sites), or C45.9 (mesothelioma, unspecified).. † Age-adjusted deaths ... mesothelioma of pericardium), C45.7 (mesothelioma of other sites), and C45.9 (mesothelioma, unspecified). ...
https://www.cdc.gov/mmwr/volumes/71/wr/mm7119a1.htm
OPERATE NOW!: PERICARDIUM SURGERY onlinespel | POMU SpelOPERATE NOW!: PERICARDIUM SURGERY onlinespel | POMU Spel
Pericardium Surgery vid pomu.se. Du kan hitta fler gratis spel som Operate Now!: Pericardium Surgery in Sjukhus Spel sektionen. ...
http://www.pomu.se/spela/operate-now-pericardium-surgery.html
Congenital Absence of the Pericardium | Radiology Key
33.1, 33.2, and 33.3). Left-sided absence of the pericardium allows extension of the main pulmonary artery beyond the confines ... Partial absence of the pericardium. Panel (a) is an axial scan in a patient with a history of a mitral valve replacement shows ... Partial absence of the pericardium. An example of a 54-year-old man with known tricuspid insufficiency and who underwent a ... Congenital absence of the pericardium is an abnormality characterized by a spectrum of findings ranging from a small defect to ...
https://radiologykey.com/congenital-absence-of-the-pericardium/
Constrictive Pericarditis: Background, Pathophysiology, EtiologyConstrictive Pericarditis: Background, Pathophysiology, Etiology
The normal pericardium is composed of 2 layers: the tough fibrous parietal pericardium and the smooth visceral pericardium. ... 1] This usually involves the parietal pericardium, although it can involve the visceral pericardium (see Constrictive-Effusive ... which may either resolve or organize to form adhesions between the visceral pericardium and the parietal pericardium. This ... Any operative or invasive procedure in which the pericardium is opened, manipulated, or damaged may invoke an inflammatory ...
https://www.medscape.com/answers/157096-196886/what-is-the-role-of-trauma-in-the-etiology-of-constrictive-pericarditis
Lungs and Heart with Pericardium - Medical Stock Images CompanyLungs and Heart with Pericardium - Medical Stock Images Company
... where the heart is surrounded by the pericardium. ... Front view of figure, lungs, heart, rib cage, pericardium.. ... Illustration of heart and lungs, where the heart is surrounded by the pericardium. ...
https://www.medicalstockimages.net/products/lungs-and-heart-with-pericardium-2
Drinking From The Giant Tortoise Pericardium - The Skeptical CardiologistDrinking From The Giant Tortoise Pericardium - The Skeptical Cardiologist
The Pericardium. The pericardium is the sac around the heart. I am very familiar with the pericardium in humans as I look at it ... Drinking FromThe Pericardium Of The Giant Tortoise. Finally, as this is a cardiology-oriented site I must take note of the ... Thus, in a normal giant tortoise one would not expect more than an ounce of liquid in the pericardium-hardly worth butchering ... I asked Jim Scharff, a cardiothoracic surgeon,who slices open the pericardium of humans on a daily basis what he typically ...
https://theskepticalcardiologist.com/2018/07/28/drinking-from-the-giant-tortoise-pericardium/?replytocom=3361
International Classification of Diseases (ICD) Codes
Mesothelioma of pericardium. *Mesothelioma of other sites. *Mesothelioma, unspecified. C45 Other Interstitial Pulmonary ...
https://wwwn.cdc.gov/eWorld/Appendix/ICDCodes
Table A1 - Multidrug-Resistant Acinetobacter baumannii in Veterinary Clinics, Germany - Volume 17, Number 9-September 2011 -...
Pericardium. A1. ND. ND. 13. 1237. baum.. 2001 Mar 12. Giessen. CVK. Dog. Urine. C1. ND. ND. 3. ...
https://wwwnc.cdc.gov/eid/article/17/9/10-1931-ta1.htm
Asbestos Toxicity: What Respiratory Conditions Are Associated with Asbestos? | Environmental Medicine | ATSDRAsbestos Toxicity: What Respiratory Conditions Are Associated with Asbestos? | Environmental Medicine | ATSDR
Pericardium,. *Tunica vaginalis testis, and. *Outer surface of ovaries.. It is a rare neoplasm, accounting for less than 5% of ...
https://www.atsdr.cdc.gov/csem/asbestos/respiratory_conditions_associated_with_asbestos.html
Congenital total absence of the pericardium: A case report - Open Medicine - Volume 5, Issue 3 (2010) - PSJD - Yadda
9] Skalski J., Wites M., Haponiuk I., Przylski R., Grzybowski A., Zembala M., et al., A congenital defect of the pericardium, ... 5] Nisanoglu V., Erdil N., Battaloglu B., Complete Left- Sided Absence of the Pericardium in Association with Reuptured Type A ... 6] Tebruegge M.O., Rennie J.M., Haugen S.E., congenital absence of the pericardium associated with congenital diaphragmatic ... 3] Tan R.S., Partridge J., Ilsley C., Mohiaddin R., Familial complete congenital absence of the pericardium, Clinical Radiology ...
http://psjd.icm.edu.pl/psjd/element/bwmeta1.element.-psjd-doi-10_2478_s11536-009-0018-5
Bovine pericardiumPericarditisCalled the parietal pericardiumMEMBRANEGreat vesselsFibrousConnective tissueCongenitalLungsInflammationSerousSurgeryCardiacMesothelialEchocardiographyAbsenceMembranesEpicardiumMeridianLayers of the pericardiumPericardial effusionDiastoleLungPleuralValvesSurgicalFluidAutopsyCoronaryHumansOuterChest painManifestation
Bovine pericardium18
  • The aim of this study was to describe our initial experience with the use of equine pericardium and its safety and advantages and disadvantages compared to bovine pericardium. (autotissue.de)
  • Equine pericardium was used in 58 patients and bovine pericardium was used in 53 patients. (autotissue.de)
  • Postoperative transcatheter intervention was needed in 2 patients (1.8%): one for dilatation of aortic arch stenosis after repair of hypoplastic left heart syndrome with equine pericardium and one for dilatation of pulmonary artery branches after repair of tetralogy of Fallot using bovine pericardium. (autotissue.de)
  • It may be preferable to bovine pericardium in cases requiring a complex shape or a pliable patch as in arch reconstruction or for valve reconstruction. (autotissue.de)
  • PURPOSE: To compare the use of human donor sclera with bovine pericardium as patch graft material for a glaucoma drainage device (GDD), with respect to the incidence of tube exposure, and to study the role of a drainage suture. (vumc.nl)
  • 163 in the human donor sclera cohort and 81 in the bovine pericardium cohort with a median follow-up of 31 and 36 months, respectively. (vumc.nl)
  • RESULTS: In the bovine pericardium cohort, eleven (13.6%) eyes developed tube exposure compared to none in the human donor sclera cohort. (vumc.nl)
  • Within the bovine pericardium cohort, eyes with a drainage suture experienced more tube exposure, although this difference was not statistically significant (p = 0.09). (vumc.nl)
  • CONCLUSION: Human donor sclera leads to less tube exposure than bovine pericardium. (vumc.nl)
  • With bovine pericardium, but not with donor sclera, exposure tends to be enhanced by a drainage suture. (vumc.nl)
  • abstract = "PURPOSE: To compare the use of human donor sclera with bovine pericardium as patch graft material for a glaucoma drainage device (GDD), with respect to the incidence of tube exposure, and to study the role of a drainage suture.METHODS: All GDD surgeries between 2010 and 2014 performed at the VU Medical Center were examined in this comparative, retrospective cohort study. (vumc.nl)
  • Secondary outcomes were postoperative intraocular pressure (IOP), number of glaucoma medications and the effect of a drainage suture.RESULTS: In the bovine pericardium cohort, eleven (13.6%) eyes developed tube exposure compared to none in the human donor sclera cohort. (vumc.nl)
  • Within the bovine pericardium cohort, eyes with a drainage suture experienced more tube exposure, although this difference was not statistically significant (p = 0.09).CONCLUSION: Human donor sclera leads to less tube exposure than bovine pericardium. (vumc.nl)
  • They shown the results with 11 patients operated by BENTALL and DE BONO techniques with an open bovine pericardium IMC tubular and valvular graft without dead due to technic or due to the graft utilized. (bjcvs.org)
  • SPINALE, F. - Bovine pericardium for conection of congenital heart defects. (bjcvs.org)
  • The feasibility of untreated bovine pericardium xenograft as biomaterial for the lining of the small intestine anastomosis in horses to avoid dehiscences, leakage, fistulas and formation of adhesions in the postoperative period was investigated. (edu.pe)
  • It is concluded that untreated bovine pericardium xenograft is viable and effective because it reinforces the cicatricial remodeling process, avoiding possible anastomotic leakage and peritonitis. (edu.pe)
  • Aguilar Guevara, CN , Alfredo Delgado, C , Alfonso Chavera, C & Medalí Cueva, R 2018, ' End-to-end jejunal anastomosis with bovine pericardium xenograft in equines ', Revista de Investigaciones Veterinarias del Peru , pp. 106-119. (edu.pe)
Pericarditis9
  • In patients with pericarditis, the pericardium already has lost its lubricating ability so removing it does not make that situation worse. (onteenstoday.com)
  • Constrictive pericarditis occurs when a thickened fibrotic pericardium, of whatever cause, impedes normal diastolic filling. (medscape.com)
  • [ 1 ] This usually involves the parietal pericardium, although it can involve the visceral pericardium (see Constrictive-Effusive Pericarditis ). (medscape.com)
  • This often leads to pericardial organization, chronic fibrotic scarring, and calcification, most often involving the parietal pericardium (see Constrictive-Effusive Pericarditis for visceral pericardial disease). (medscape.com)
  • Pericarditis is swelling and irritation of the thin, saclike tissue surrounding the heart (pericardium). (drugs.com)
  • Some people with long-term pericarditis develop permanent thickening and scarring of the pericardium. (drugs.com)
  • Although the pleurae and pericardium share certain histologic characteristics, asbestos -related pericarditis is rarely reported. (cdc.gov)
  • Discussion: Based on the patient's occupational history, the presence of pleural pathology consistent with asbestos , previous evidence that asbestos can affect the pericardium, and absence of other likely explanations, we concluded that his pericarditis was asbestos -related. (cdc.gov)
  • Constrictive pericarditis results in a thickened and less-elastic pericardium, which can lead to incomplete diastolic filling and myocardial ischemia [ 1 ]. (biomedcentral.com)
Called the parietal pericardium1
  • The outer layer of the pericardium is called the parietal pericardium. (onteenstoday.com)
MEMBRANE1
  • cardiology) a serous membrane that surrounds the heart allowing it to contract while epicardium is (anatomy) the layer of tissue between the pericardium and the heart. (onteenstoday.com)
Great vessels1
  • Also, the parietal paricardium is continuous with the visceral pericardium across the points at which the great vessels traverse the pericardial cavity. (gpnotebook.com)
Fibrous9
  • The pericardium is the fibrous sac that surrounds the heart. (onteenstoday.com)
  • It can be divided into three layers, the fibrous pericardium, the parietal pericardium, and the visceral pericardium. (onteenstoday.com)
  • Enclosed within the fibrous pericardium, the serous pericardium is itself divided into two layers: the outer parietal layer that lines the internal surface of the fibrous pericardium and the internal visceral layer that forms the outer layer of the heart (also known as the epicardium). (onteenstoday.com)
  • The pericardium consists of two layers: the fibrous and the serous. (onteenstoday.com)
  • The parietal layer of serous pericardium is a mesothelial layer of cells which lines the inner layer of the fibrous pericardium. (gpnotebook.com)
  • The normal pericardium is composed of 2 layers: the tough fibrous parietal pericardium and the smooth visceral pericardium. (medscape.com)
  • Parietal layer - It lines the inner side of the fibrous pericardium and is difficult to separate from the structure. (knowyourbody.net)
  • Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. (bvsalud.org)
  • The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers. (bvsalud.org)
Connective tissue1
  • The pericardium is a simple structure composed of connective tissue lined by a single layer of mesothelial cells that encases the heart. (onteenstoday.com)
Congenital10
  • Equine pericardium: a versatile alternative reconstructive material in congenital cardiac surgery. (autotissue.de)
  • Equine pericardium is a safe patch material for reconstruction in congenital heart surgery. (autotissue.de)
  • IMSEAR at SEARO: Congenital asymptomatic absence of pericardium. (who.int)
  • Sivaprasad M, Iyer KS, Venugopal P. Congenital asymptomatic absence of pericardium. (who.int)
  • An interesting congenital anomaly of the pericardium is its absence. (who.int)
  • Congenital absence of the pericardium is an abnormality characterized by a spectrum of findings ranging from a small defect to complete absence of the pericardium. (radiologykey.com)
  • Transthoracic echocardiography and a computerized axial tomography scan showed evidence of complete absence of the pericardium, which is a rare congenital heart defect. (edu.pl)
  • Congenital Partial Absence of the Left Pericardium Associated with Tricuspid Regurgitation, Ann Thorac Surg. (edu.pl)
  • 8] Ratib O., Perloff J.K., Williams W.G., Congenital Complete Absence of the Pericardium. (edu.pl)
  • A congenital defect of the pericardium, Thorac Cardiovasc Surg. (edu.pl)
Lungs1
Inflammation2
  • But if the pericardium is diseased or injured, the resulting inflammation can lead to excess fluid. (onteenstoday.com)
  • However, an elevated WBC level is suggestive of an inflammation within the pericardium. (medscape.com)
Serous3
Surgery1
  • After discourse about the methods complications and difficulties, we deduced that the thecnique employed is the choice from the treatment of this disease and pericardium valvar bovine graft turns the surgery more easy because it is flexible and hemostatic and doesn't need an hemostatic preparation before implantation. (bjcvs.org)
Cardiac3
  • 2 Although most cases are asymptomatic, patients with partial absence of the pericardium (PAoP) may experience chest pain, palpitations, syncope or even sudden death secondary to herniation of cardiac structures through the pericardial defect. (analesdepediatria.org)
  • Cardiac tamponade secondary to gastric adenocarcinoma in the pericardium. (medigraphic.com)
  • A computed tomography (CT) scan showed a 2-cm right middle lobe nodule adjacent to the cardiac border and mediastinal lymphadenopathy abutting the superior vena cava and anterior pericardium ( Figure 1 ). (cdc.gov)
Mesothelial1
  • The mesothelial cells secrete mucopolysaccharide, which lubricates the pericardium, allowing the heart to expand and contract with limited resistance. (onteenstoday.com)
Echocardiography2
  • Echocardiography showed a mass of the pericardium. (biomedcentral.com)
  • 25] Echocardiography is an invaluable tool for differentiating tumors arising from the pericardium and/or myocardium from other tumors. (medscape.com)
Absence2
Membranes1
  • It is one of the layers of the Pericardium, one of the sac-like membranes that circumvent the heart. (knowyourbody.net)
Epicardium1
Meridian1
  • The name of "Daling" means the accumulation of splenic soil that follow the pericardium meridian flushing down. (peakmassager.com)
Layers of the pericardium2
  • What are the 3 layers of the pericardium? (onteenstoday.com)
  • The chest pain occurs when the irritated layers of the pericardium rub against each other. (drugs.com)
Pericardial effusion1
  • Findings of the CT include significant pericardial effusion with abnormal enhancement of the pericardium and few pockets of air within the effusion, and bilateral small pleural effusion. (medpagetoday.com)
Diastole1
  • After early diastole, the stiff pericardium affects flow and hemodynamics. (medscape.com)
Lung1
  • In a 33 year old man with no discernible immunologic defect, invasive aspergillosis developed in both the pericardium and lung with marked granulomatous reaction. (elsevier.com)
Pleural2
  • A high-resolution computerized tomography scan of the chest demonstrated dense calcification in the pericardium, right pleural thickening and nodularity, right pleural plaque without calcification, and density in the right middle lobe. (cdc.gov)
  • Relevance to clinical practice: Similar to pleural thickening and plaque formation, asbestos may cause progressive fibrosis of the pericardium. (cdc.gov)
Valves1
  • Diseases of the valves and pericardium. (who.int)
Surgical1
  • Diseases of the pericardium: morphologic study of surgical specimens from 35 patients. (humpath.com)
Fluid1
  • The pericardial space is defined as the cavity between the visceral and parietal pericardium and it normally contains 10-50 mL of fluid. (clinmedjournals.org)
Autopsy1
  • On consulting the post-mortem records of St. Mary's Hospital for the years 1890 - 93, I noted that, out of eighty-six cases in which death was attributable to heart disease, in no fewer than thirty-one was adherent pericardium found at the autopsy - in the majority of cases, viz. (forgottenbooks.com)
Coronary4
  • Coronary computed tomography angiography (CCTA) showed a huge pseudoaneurysm located in pericardium. (biomedcentral.com)
  • Coronary angiography revealed the LCX pericardia fistula. (biomedcentral.com)
  • Coronary computed tomography angiography (CCTA) demonstrated that the distal segment of the LCX was significantly dilated with contrast agent filling and with huge thrombi (Fig. 1 a) in the pericardium. (biomedcentral.com)
  • The patient underwent the coronary angiography and selective micro catheter angiography of the LCX, which revealed a distal fistula of the LCX communicating with the pericardium (Fig. 2 ). (biomedcentral.com)
Humans1
  • I am very familiar with the pericardium in humans as I look at it on every one of the many echocardiograms I read. (theskepticalcardiologist.com)
Outer1
  • The heart on the left shows the typical outer lining of the heart (pericardium). (drugs.com)
Chest pain1
Manifestation1
  • It reflects the therapeutic insight that breast accumulations are most often a manifestation of pathological changes in the jueyin Pericardium system, which requires the use of the representative j ueyin remedy Danggui Sini Tang. (classicalpearls.eu)