Penis
Penile Erection
Erectile Dysfunction
Clitoris
Penile Induration
Priapism
Penile Prosthesis
Genitalia, Male
Tuberculosis, Male Genital
Hypospadias
Penile Implantation
Genital Diseases, Male
Stuttering
Etilefrine
Nitric oxide release in penile corpora cavernosa in a rat model of erection. (1/1135)
1. Nitric oxide (NO) levels were measured in the corpus cavernosum of urethane-anaesthetized rats by using differential normal pulse voltammetry with carbon fibre microelectrodes coated with a polymeric porphyrin and a cation exchanger (Nafion). A NO oxidation peak could be recorded at 650 mV vs. a Ag-AgCl reference electrode every 100 s. 2. This NO signal was greatly decreased by the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME), given by local and systemic routes, and enhanced by the NO precursor L-arginine. Treatment with L-arginine reversed the effect of L-NAME on the NO peak. 3. Both the NO signal and the intracavernosal pressure (ICP) were increased by electrical stimulation of cavernosal nerves (ESCN). However, the rise in the NO levels long outlived the rapid return to baseline of the ICP values at the end of nerve stimulation. 4. The ICP and the NO responses to ESCN were suppressed by local and systemic injections of L-NAME. Subsequent treatment with L-arginine of L-NAME-treated animals restored the NO signal to basal levels and the NO response to ESCN. The ICP response to ESCN was restored only in part by L-arginine. 5. The observed temporal dissociation between the NO and ICP responses could be accounted for by several factors, including the buffering of NO by the blood filling the cavernosal spaces during erection. 6. These findings indicate that an increased production of NO in the corpora cavernosa is necessary but not sufficient for maintaining penile erection and suggest a complex modulation of the NO-cGMP-cavernosal smooth muscle relaxation cascade. (+info)Concordant induction of cyclin E and p21cip1 in differentiated keratinocytes by the human papillomavirus E7 protein inhibits cellular and viral DNA synthesis. (2/1135)
Productive infections by human papillomaviruses (HPVs) occur only in differentiated keratinocytes in squamous epithelia in which the HPV E7 protein reactivates the host DNA replication machinery to support viral DNA replication. In a fraction of the differentiated keratinocytes, E7 also posttranscriptionally induces p21Cip1, which is distributed in a mutually exclusive manner with unscheduled cellular DNA synthesis. In this study, double immunofluorescence labeling unexpectedly revealed that E7 caused a concordant accumulation of both cyclin E and p21Cip1 to high levels in patient papillomas and in organotypic cultures of primary human keratinocytes. The induction of cyclin E is mutually exclusive with unscheduled cellular DNA synthesis or abundant viral DNA. These novel virus-host interactions in differentiated keratinocytes are in contrast to previous observations made in submerged proliferating cultures, in which HPV E7 induces cyclin E and overcomes p21Cip1 inhibition of S-phase entry. We propose that an appropriately timed induction of cyclin E/cyclin-dependent kinase 2 by HPV E7 in postmitotic cells enables S-phase reentry and HPV DNA amplification, whereas prematurely induced cyclin E stabilizes p21Cip1 protein, which then inhibits cyclin E/cyclin-dependent kinase 2. Consequently, cyclin E and p21Cip1 both fail to turn over, and DNA synthesis does not occur. (+info)Determination of intrapenial blood volume using 99mTc-labeled autologous red blood cells. (3/1135)
In 17 impotent patients, radioisotope penography was performed using 99mTc-red blood cells (the patient's own red blood cells labeled with 99mTc) for the quantitative analysis of intrapenial blood volume. A visual sexual stimulation (VSS) was given to the patient after injecting the 99mTc-red blood cells. Patients showing a complete erection had their intrapenial blood volumes 4.2-11.2 times greater than before VSS (mean increase, 8.0 times). In cases of incomplete erection after VSS the intrapenial blood volumes were 3.3-7.0 times greater than before VSS (mean increase, 4.9 times). In cases showing a gentle rise in their penogram curves without evidence of an erection, intrapenial blood volumes after VSS were 2.0-3.3 times those before VSS (mean increaae, 2.9 times). By contrast, in cases showing no response to the VSS or no rise in penogram curve, post-VSS increases in intrapenial pool of blood were very slight, slight, only 1.4-1.7 times the original volume of blood. (+info)Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture. (4/1135)
Glutathione S-transferase (GST) M1 is a member of the GST mu family of cytosolic enzymes that have been hypothesized to catalyze the conjugation of glutathione to a large number of hydrophobic substances, including carcinogens such as polynuclear aromatic hydrocarbons present in tobacco smoke, leading to their excretion. Epidemiologic and experimental evidence suggests that the risk of cervical cancer is related to both human papillomavirus (HPV) infection and cigarette smoking. We compared the enzymatic activities and mRNA levels of GSTs in GSTM1-positive human cervical keratinocytes (HCKs) that had been transfected with HPV16 with those in the parental cells. The GSTM1 activity toward the substrate trans-stilbene oxide was 5- to 7-fold lower than in the parental cells. The relative mRNA level in HCK transfected with HPV16 E6/E7, as quantified by reverse transcriptase-polymerase chain reaction (RT-PCR) with normalization against endogenous glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression, was 6% that of the parental cells. It was 16 and 82%, respectively, in cells that were transfected with HPV16 E6 alone or HPV16 E7 alone. When quantified by competitive RT-PCR using an exogenous nuclease-resistant synthetic cyclophilin RNA transcript as control, the mRNA level in HCK transfected with HPV16 E6 was approximately 10-fold lower that that in the parental cells. It was approximately 5- to 7-fold lower in the HPV16 E7 or HPV16 E6/E7 cells. Our results suggest that viral infections, through the modulation of cellular xenobiotic-metabolizing enzymes, may play a role in the ability of cells to handle environmental carcinogens. (+info)Direct and indirect modulation of ornithine decarboxylase and cyclooxygenase by UVB radiation in human skin cells. (5/1135)
Exposure to solar ultraviolet (UV) B radiation is responsible for skin inflammation and tumour progression. Cyclooxygenase and ornithine decarboxylase are believed to be involved in such processes since they participate in the synthesis of mediators of inflammation and cell differentiation, respectively. We have investigated the in vitro modulation of expression of such genes by UVB radiation in different skin cell lines. We have observed that accumulation of ornithine decarboxylase mRNA is unaffected by even high UVB doses in both human epidermal keratinocytes and dermal fibroblasts, whereas cyclooxygenase-2 levels were significantly up-regulated by low UVB doses in KB human epidermoid keratinocytes. Depletion of total intracellular glutathione levels in KB cells amplified the activation, revealing a role for an oxidative component of UVB in modulating cyclooxygenase gene expression. Transfer of medium from UVB irradiated keratinocytes to fibroblasts resulted in a significant activation of cyclooxygenase expression and activity, while ornithine decarboxylase levels were unaffected. We conclude that UVB radiation can activate cyclooxygenase gene expression in human skin cells both by direct activation pathways or indirectly by inducing a paracrine mechanism. (+info)Effects of hydroxocobalamin and carboxy-PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles. (6/1135)
The effects of carboxy-PTIO and hydroxocobalamin were studied on nitrergic transmission in anococcygeus and retractor penis muscles taken during post mortem examination from young male pigs. In both muscles under resting conditions, electrical field stimulation (EFS) caused contractions that were sensitive to tetrodotoxin (1 microM) and were greatly inhibited by prazosin (1 microM) and guanethidine (10-30 microM), but were not significantly affected by atropine (1 microM). In the anococcygeus muscle, but not in the retractor penis muscle, guanethidine produced a prolonged contraction. After tone was raised by guanethidine in the anococcygeus or by phenylephrine (1 microM) in the presence of guanethidine in the retractor penis, EFS caused tetrodotoxin-sensitive relaxations. The EFS-induced relaxations were abolished by the NO synthase inhibitor N(G)-L-nitro-arginine methyl ester (L-NAME; 100 microM) and its effect was partly overcome by L-arginine (1 mM), indicating it was mediated by nitrergic nerves. Carboxy-PTIO (0.1-1 mM) had no significant effect in reducing stimulation-induced nitrergic relaxations in either muscle. However, hydroxocobalamin (0.1-1 mM) caused concentration-dependent reductions of nitrergic relaxations in both muscles. Relaxations to exogenous nitric oxide (1 microM) in both muscles were abolished by carboxy-PTIO (0.3 mM) and hydroxocobalamin (0.1 mM). There were no differences in reactivity to carboxy-PTIO or hydroxocobalamin between anococcygeus and retractor penis muscles from the same species (pig). The finding also confirms earlier observations that the nitrergic transmitter is generally resistant to the NO-scavenger carboxy-PTIO. (+info)Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence. (7/1135)
We designed and evaluated a new class of molecules, nitrosylated alpha-adrenergic receptor antagonists, as potential agents for the treatment of impotence. In in vitro studies with human and rabbit corpus cavernosum strips in organ chambers, the alpha-adrenergic receptor antagonists (alpha-ARAs) moxisylyte and yohimbine and their corresponding nitrosylated compounds, SNO-moxisylyte (NMI-221) and SNO-yohimbine (NMI-187), concentration-dependently relaxed endothelin-induced contraction. The nitrosylated compounds were significantly more potent than the parent alpha-ARA. In human tissues, the specific phosphodiesterase type 5 inhibitor zaprinast potentiated the relaxing effects of the nitrosylated compounds. Only nitrosylated compounds induced accumulation of cyclic GMP in rabbit corpus cavernosum strips. Yohimbine and NMI-187 demonstrated a potent alpha2-blocking activity, with no significant differences in pA2 values (8.9 versus 8.2, respectively). Moxisylyte and NMI-221 showed moderate potency in antagonizing phenylephrine contraction, with comparable pA2 values for both molecules (6.5 versus 6.6, respectively). alpha-Adrenergic receptor-binding studies showed similar binding affinities for the alpha-ARA and their corresponding nitrosylated compounds. In vivo, intracavernosal injection of nitrosylated molecules caused greater increases in intracavernosal pressure (NMI-221 versus moxisylyte) that were more long lasting than those of moxisylyte or yohimbine. There were no significant differences between nitrosylated and non-nitrosylated compounds in the magnitude of systemic mean arterial pressure decrease after intracavernosal injection. alpha-ARA and the nitrosylated compounds showed no pain-inducing activity as evaluated with the paw-lick model in mice. In summary, nitrosylated alpha-ARA have the dual functionalities of nitric oxide donors and alpha-ARA. These drugs induced penile erection in animals, suggesting their possible therapeutic value as agents for the local pharmacological treatment of impotence. (+info)NO synthase in cholinergic nerves and NO-induced relaxation in the rat isolated corpus cavernosum. (8/1135)
1. In the rat corpus cavernosum (CC), the distribution of immunoreactivity for neuronal and endothelial NO synthase (nNOS and eNOS), and the pattern of NOS-immunoreactive (-IR) nerves in relation to some other nerve populations, were investigated. Cholinergic nerves were specifically immunolabelled with antibodies to the vesicular acetylcholine transporter protein (VAChT). 2. In the smooth muscle septa surrounding the cavernous spaces, and around the central and helicine arteries, the numbers of PGP- and tyrosine hydroxylase (TH)-IR terminals were large, whereas neuropeptide Y (NPY)-, VAChT-, nNOS-, and vasoactive intestinal polypeptide (VIP)-IR terminals were found in few to moderate numbers. 3. Double immunolabelling revealed that VAChT- and nNOS-IR terminals, VAChT- and VIP-IR terminals, nNOS-IR and VIP-IR terminals, and TH- and NPY-IR terminals showed coinciding profiles, and co-existence was verified by confocal laser scanning microscopy. TH immunoreactivity was not found in VAChT-, nNOS-, or VIP-IR nerve fibres or terminals. 4. An isolated strip preparation of the rat CC was developed, and characterized. In this preparation, cumulative addition of NO to noradrenaline (NA)-contracted strips, produced concentration-dependent, rapid, and almost complete relaxations. Electrical field stimulation of endothelin-1-contracted preparations produced frequency-dependent responses: a contractile twitch followed by a fast relaxant response. After cessation of stimulation, there was a slow relaxant phase. Inhibition of NO synthesis, or blockade of guanylate cyclase, abolished the first relaxant phase, whereas the second relaxation was unaffected. 5. The results suggest that in the rat CC, nNOS, VAChT- and VIP-immunoreactivities can be found in the same parasympathetic cholinergic neurons. Inhibitory neurotransmission involves activation of the NO-system, and the release of other, as yet unknown, transmitters. (+info)Penile neoplasms refer to abnormal growths or tumors that develop on the penis. These growths can be benign (non-cancerous) or malignant (cancerous). Benign penile neoplasms include conditions such as fibromas, papillomas, and granulomas, while malignant neoplasms include penile cancer. Penile cancer is a relatively rare type of cancer, but it can be aggressive and difficult to treat if not detected early. Treatment options for penile neoplasms depend on the type, size, and location of the growth, as well as the overall health of the patient.
Erectile dysfunction (ED) is a medical condition in which a man is unable to achieve or maintain an erection sufficient for sexual activity. It is also known as impotence. ED can be caused by a variety of factors, including physical, psychological, and lifestyle factors. Physical causes of ED may include conditions such as diabetes, high blood pressure, and heart disease. Psychological causes may include stress, anxiety, and depression. Lifestyle factors such as smoking, excessive alcohol consumption, and a sedentary lifestyle can also contribute to ED. Treatment for ED may include lifestyle changes, medications, and in some cases, surgery.
The clitoris is a small, sensitive organ located at the front of the vulva in females. It is composed of erectile tissue and is surrounded by a hood of skin called the clitoral hood. The clitoris is a part of the female genitalia and is involved in sexual pleasure and arousal. It is also a source of sexual sensation and can be stimulated for sexual pleasure. The clitoris is not connected to the reproductive system and does not play a role in reproduction.
Penile induration, also known as Peyronie's disease, is a condition in which the penis becomes hardened and curved due to the formation of scar tissue in the tunica albuginea, the outer layer of the penis. This scar tissue can cause the penis to bend or curve during an erection, which can be painful and can also make sexual intercourse difficult or impossible. Penile induration is a relatively common condition, and it can affect men of all ages. It is usually treated with medications, physical therapy, or surgery, depending on the severity of the condition.
Balanitis is a medical condition that refers to the inflammation or infection of the glans penis, which is the sensitive head of the penis. It is a common condition that can affect men of all ages, and it can be caused by a variety of factors, including bacterial or fungal infections, allergic reactions, trauma, or certain medical conditions such as diabetes or psoriasis. Symptoms of balanitis may include redness, swelling, itching, burning, pain, discharge from the penis, and difficulty urinating or having sex. Treatment for balanitis typically involves identifying and treating the underlying cause of the inflammation or infection, which may involve the use of antibiotics, antifungal medications, or other treatments depending on the specific cause. In some cases, lifestyle changes such as improving hygiene or avoiding certain irritants may also be recommended to prevent recurrence of the condition.
Priapism is a medical condition in which a man's penis becomes erect and stays that way for an extended period of time, even without sexual stimulation or desire. It can be a painful and distressing condition, and if left untreated, it can lead to permanent damage to the penis. There are two main types of priapism: low-flow priapism and high-flow priapism. Low-flow priapism occurs when blood flow into the penis is restricted, while high-flow priapism occurs when blood flow into the penis is increased. Priapism can be caused by a variety of factors, including medications, medical conditions, and injuries. It can also occur as a side effect of certain medications, such as antidepressants and blood thinners. Treatment for priapism typically involves addressing the underlying cause of the condition and reducing blood flow to the penis. In some cases, medications may be used to help reduce inflammation and pain. In severe cases, surgery may be necessary to correct the underlying problem and prevent permanent damage to the penis.
Circumcision, male refers to the surgical removal of the foreskin, the skin that covers the head of the penis, in males. It is a common surgical procedure performed for various reasons, including religious, cultural, and medical reasons. In the medical field, circumcision is often performed for the following reasons: 1. To prevent or reduce the risk of sexually transmitted infections (STIs), including HIV, due to the reduced number of skin folds that can harbor bacteria and viruses. 2. To treat or prevent phimosis, a condition in which the foreskin is too tight to be retracted over the head of the penis. 3. To treat or prevent balanitis, an inflammation of the foreskin or head of the penis. 4. To treat or prevent penile cancer, although this is a rare condition. Circumcision is typically performed under local anesthesia, and the procedure usually takes about 30 minutes to an hour. The recovery period is usually short, and most men can return to normal activities within a few days. However, complications can occur, including bleeding, infection, and pain, and it is important to follow proper aftercare instructions to minimize the risk of complications.
Tuberculosis of the male genital organs is a rare form of tuberculosis that affects the male reproductive system. It is caused by the same bacterium that causes tuberculosis in other parts of the body, Mycobacterium tuberculosis. The infection can affect any part of the male genital system, including the testicles, epididymis, prostate gland, and seminal vesicles. Symptoms of tuberculosis of the male genital organs may include pain or discomfort in the testicles or scrotum, swelling or enlargement of the testicles, difficulty urinating, and pain during sexual intercourse. In some cases, there may be no symptoms at all. Diagnosis of tuberculosis of the male genital organs typically involves a combination of physical examination, imaging studies, and laboratory tests. A biopsy of the affected tissue may be necessary to confirm the diagnosis. Treatment for tuberculosis of the male genital organs typically involves a long course of antibiotics, usually for at least six months. In some cases, surgery may be necessary to remove infected tissue or drain abscesses. It is important to complete the full course of treatment to prevent the development of drug-resistant strains of tuberculosis.
Hypospadias is a congenital (present at birth) condition in which the opening of the urethra is not located at the tip of the penis, but instead on the underside or on the side of the penis. This can result in a range of physical abnormalities, including a curved penis, a small or missing foreskin, and a urinary meatus (the opening through which urine exits the body) that is located on the underside of the penis. In severe cases, the urethra may not open at all, requiring surgical intervention to correct the condition. Hypospadias is relatively common, affecting about 1 in every 250 male births. It can occur in isolation or as part of a syndrome that affects other parts of the body.
In the medical field, copulation refers to the sexual act of penetration between a male and female reproductive organ, typically involving intercourse. It is a common form of sexual activity and is often associated with reproduction, although it can also occur for pleasure or other reasons. Copulation typically involves the penis penetrating the vagina, although other forms of sexual activity, such as anal or oral sex, can also occur. It is important to note that copulation can carry risks, including the transmission of sexually transmitted infections (STIs) and unwanted pregnancies, and it is important to practice safe sex to minimize these risks.
Genital diseases in males refer to medical conditions that affect the male reproductive system, including the testes, prostate gland, penis, and related structures. These conditions can be acute or chronic, and can range from minor infections to more serious conditions that can affect fertility and overall health. Some common examples of genital diseases in males include sexually transmitted infections (STIs) such as chlamydia, gonorrhea, and syphilis, as well as non-infectious conditions such as erectile dysfunction, prostate cancer, and varicocele (swelling of the veins in the scrotum). Diagnosis of genital diseases in males typically involves a physical examination, medical history, and laboratory tests such as blood tests, urine tests, and imaging studies. Treatment options depend on the specific condition and may include medications, surgery, or other interventions. It is important for males to seek medical attention if they experience any symptoms of a genital disease, as prompt diagnosis and treatment can help prevent complications and improve outcomes.
Stuttering is a speech disorder characterized by involuntary repetitions, prolongations, or blocks of sounds, syllables, or words during speech. It can affect the fluency and clarity of speech, making it difficult for individuals to communicate effectively. Stuttering can occur at any age, but it is most commonly diagnosed in childhood. It is a complex disorder that is not fully understood, and there is no single cause. Treatment options for stuttering include speech therapy, behavioral therapy, and medication.
Etilerfrine is a sympathomimetic amine medication that is used to treat symptoms of bronchial asthma and other respiratory conditions. It works by narrowing the airways in the lungs, making it easier to breathe. Etilerfrine is available in both oral and inhaler forms and is typically used to relieve acute symptoms of asthma or other respiratory conditions. It is also sometimes used to treat low blood pressure or to increase heart rate in people who are experiencing a slow heart rate. Etilerfrine can cause side effects such as nervousness, tremors, and rapid heartbeat, and it should be used with caution in people with certain medical conditions, such as high blood pressure or heart disease.
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Glans5
- Glans: the free end of the penis. (wikipedia.org)
- The foreskin covers the head (glans) of the penis. (medlineplus.gov)
- Skin cancer can occur anywhere on the penis, but it most commonly occurs at the glans penis (the cone-shaped end of the penis), especially. (msdmanuals.com)
- Hence, the distal extension of the spongiosum, the glans penis, covers the tips of the corpora cavernosa to provide a cushioning effect. (medscape.com)
- The edge of the glans overhangs the shaft of the penis, forming a rim called the corona. (medscape.com)
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Urethra5
- In most species of animals in which there is an organ that might be described as a penis, it has no major function other than intromission, or at least conveying the sperm to the female, but in the placental mammals the penis bears the distal part of the urethra, which discharges both urine during urination and semen during copulation. (wikipedia.org)
- The urethra is on the ventral side of the body of the penis. (wikipedia.org)
- The shaft of the penis surrounds the urethra and is connected to the pubic bone. (medlineplus.gov)
- Anomalies of the penis and urethra. (medlineplus.gov)
- They are non-invasive , making them preferable to surgical implants, injections into the penis, or suppositories that go into the urethra. (healthnews.com)
Erection13
- Priapism is a prolonged, unwanted erection of the penis. (medicinenet.com)
- Blood is not able to leave the penis causing the erection. (medicinenet.com)
- Different methods of obtaining an erection may lead to different size measurements - men in the study who became aroused through oral sex reported larger penis size on average than those who attained erections through fantasizing, Herbenick said. (nbcnews.com)
- We don't know if that means that when men have oral sex that it's more arousing and they get a bigger erection, or means that men who have bigger penises could be getting more oral sex in the first place," Herbenick told LiveScience. (nbcnews.com)
- Vacuum erection devices (penis pumps) are an effective non-invasive treatment for erectile dysfunction with a low risk of serious side effects. (healthnews.com)
- Vacuum erectile devices (VEDs, also called vacuum constriction devices or penis pumps) are a treatment for ED that uses suction to allow blood to flow into the penis and produce an erection. (healthnews.com)
- Using a vacuum pump, the air is pumped out of the tube holding the penis, creating a vacuum that causes blood to flow into the penis, producing an erection. (healthnews.com)
- Once the penis is erect, a penis ring is placed around the base of the penis to maintain the erection for up to 30 minutes. (healthnews.com)
- Peyronie's disease is evaluated by a physical exam of palpating plaque in the penis, examination of the erection, and by ultrasound techniques. (emedicinehealth.com)
- In severe cases, the hardened plaque reduces flexibility, causing pain and forcing the penis to bend or arc during erection. (emedicinehealth.com)
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Erectile dysfunction4
- The complications include erectile dysfunction as well as disfigurement of the penis. (medicinenet.com)
- Do Penis Pumps Help With Erectile Dysfunction (ED)? (healthnews.com)
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Scrotum3
- The penis is located above the scrotum . (medlineplus.gov)
- Penis and scrotum. (medlineplus.gov)
- The subcutaneous connective tissue of the penis and scrotum has abundant smooth muscle and is called the dartos fascia, which continues into the perineum and fuses with the superficial perineal (Colle) fascia. (medscape.com)
Average penis3
- Based on the results of the most recent study of over 15,000 people, the average penis length is 3.6 in (9.1 cm) while flaccid and 5.2 in (13.1 cm) while erect. (healthline.com)
- Even a smaller-than-average penis can tear you a new one if you're not stretched or sufficiently prepped for anal. (healthline.com)
- How Big Is the Average Penis? (nbcnews.com)
Spiny penises2
- It is theorized that the remarkable size of their spiny penises with bristled tips may have evolved in response to competitive pressure in these highly promiscuous birds, removing sperm from previous matings in the manner of a bottle brush. (wikipedia.org)
- For instance, a phylogenetic analysis-a study comparing the presence or absence of spiny penises in different organisms over time-would offer more insight. (nationalgeographic.com)
Corpora cavernosa3
- A medication that constricts blood vessels that carry blood into the penis is injected into the penis using a small (29 gauge) needle into the corpora cavernosa area of the penis. (medicinenet.com)
- Two chambers known as the corpora cavernosa run the length of the penis. (emedicinehealth.com)
- Blood flow to the corpora cavernosa is via the paired deep arteries of the penis (cavernosal arteries), which run near the center of each corpora cavernosa (see the following image). (medscape.com)
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Erect6
- the penis, which is typically coiled up in flaccid state, can reach about the same length as the animal himself when fully erect, but is more commonly about half the bird's length. (wikipedia.org)
- In many mammals, the size of a flaccid penis is smaller than its erect size. (wikipedia.org)
- The penises of even-toed ungulates are curved in an S-shape when not erect. (wikipedia.org)
- The average American man's penis is 5.6 inches (14.2 centimeters) long when erect, a new survey of 1,661 men finds. (nbcnews.com)
- The smallest erect penis in the study was about 1.6 inches (4 cm) long, and the largest was 10.2 inches (26 cm) long. (nbcnews.com)
- A VED typically consists of a rigid tube that the penis is placed into, an electric or manual vacuum pump, and a compression ring or penis ring placed on the opening of the tube that fits over the erect penis. (healthnews.com)
Girth2
- As with any other bodily attribute, the length and girth of the penis can be highly variable between mammals of different species. (wikipedia.org)
- Other work suggests bigger isn't always better: One study found that ideal penis size depends on a person's height, and another showed that girth matters more than length to most women. (nbcnews.com)
Anus2
- With the receiving partner on all fours, the giver can easily stimulate their partner's anus using a well-lubed finger before kneeling behind and inserting their penis. (healthline.com)
- Human papillomavirus (HPV) causes nearly all cervical cancers and some cancers of the vagina, vulva, penis, anus, and oropharynx. (cdc.gov)
Cancers1
- Penile Cancer Cancers of the penis are usually types of skin cancers. (msdmanuals.com)
Perineum1
- He suffered a direct blow to his perineum and penis, which initially resulted in intense pain that lasted for approximately 5-10 minutes. (medscape.com)
Shaft2
- can cause small flat or raised spots on the head or shaft of the penis. (msdmanuals.com)
- They appear as small, usually skin-colored growths shaped like domes or hairs on the shaft of the penis. (msdmanuals.com)
Painful3
- himself, so he knows that some soul refining techniques big penis pills results very painful, and it will be seriously CVS Tongkat Ali I will find you to settle this account soon! (jewishledger.com)
- Peyronie's disease is the development of plaques or scar tissue inside the penis that causes penis curvature and painful erections. (emedicinehealth.com)
- Occasionally, painful sores develop on the penis and in the gums (called penogingival syndrome). (msdmanuals.com)
Septum1
- If the penis is bumped or bent, an area where the septum attaches to the tunica albuginea may stretch beyond a limit, injuring the tunica albuginea and rupturing small blood vessels. (emedicinehealth.com)
Pills6
- As for me waiting for these later Brian Redban penis pill Xianting keep it, naturally want to chase me or go to the devil world, or go ratings male enhancement pills on eBay could I be willing to leave Tama Klemp Land, so it was another fight. (jewishledger.com)
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- Qiana Drews's question, Augustine Fleishman hurriedly replied Daoist friend Yuan, thanks for remembering, I don't feel ninety-degree 90 penis pills Rebecka Menjivar parted, and fellow Daoist has made rapid progress, so I don't feel ashamed. (jewishledger.com)
- Penis Shrinking Pills Story In Lin Fang In front Shrinking of Pills the stage, standing two young girls dressed very Story plainly with many patches on their clothes. (emailarms.com)
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Crura2
- In mammals the penis is divided into three parts: Roots (crura): these begin at the caudal border of the pelvic ischial arch. (wikipedia.org)
- It is continuous with the deep fascia of the muscles covering the crura and bulb of the penis, the ischiocavernosus and bulbospongiosus. (medscape.com)
Exercises1
- and everything you gain is guaranteed to last permanently and that means you do not have to keep doing the exercises New Penis Growth forever to maintain your results again, unlike other popular methods. (emailarms.com)
Anatomy1
- Thus, if in Freud the Oedipus complex was linked to the perception of the presence and absence of the penis (to have or to not have a penis), in Lacan, when he thinks the function of the phallus as independent of any empirical reference, this dependence on anatomy is literally excluded from the field of psychoanalysis (the question becomes the subject's position in the dialectic of being or having the phallus). (bvsalud.org)
Penile3
- Germany, red faced and with a purple penis, prompting medics to call the fire brigade to help with the unusual penile injury. (asianage.com)
- Penis pumps can be used in combination with other ED treatments, such as oral medications or penile implants. (healthnews.com)
- Pearly penile papules are abnormal growths originating in the blood vessels of the penis. (msdmanuals.com)
Small8
- By inserting a small needle and removing blood from the penis the doctor will be able to establish the oxygen content and therefore the type of priapism the patient has. (medicinenet.com)
- Is a small penis a dealbreaker? (straight.com)
- I have a small penis. (straight.com)
- But yes, a very small penis is disappointing. (straight.com)
- A biotech CEO on a quest for immortality says he wears a small device on his penis every night to. (yahoo.com)
- The former press secretary describes how Trump allegedly "called [Grisham] from Air Force One specifically to let her know his penis was not small or toadstool-shaped-which is basically confirmation that his penis is small and toadstool-shaped," joked Kimmel. (thedailybeast.com)
- It could just be one's psychological complex or it could be that they really have a small penis of which they are feeling embarrassed. (healthstatus.com)
- One's partner could put off easily by looking at the small penis size of their partner and this could hurt the feelings of the other person. (healthstatus.com)
Pump6
- A doctor explained Penis Pump. (truepenisenhancer.com)
- To use a VED , first, apply lubricant to your penis and the opening of the tube, then place the pump over the penis. (healthnews.com)
- What are the benefits of using a penis pump for ED? (healthnews.com)
- VEDs can sometimes cause bruising and some men experience discomfort from using a penis pump or penis ring. (healthnews.com)
- Is a penis pump right for you? (healthnews.com)
- If you have ED and are interested in trying a medical penis pump you should talk to your doctor or other healthcare providers. (healthnews.com)
Adult1
- an adult chimpanzee, significantly smaller (in body size) than a gorilla, has a penis size about double that of the gorilla. (wikipedia.org)
Ultrasound2
- He was diagnosticated of penis fracture with the help of ultrasound and was performed an urgent reparation. (bvsalud.org)
- The penis fracture has a clinical diagnosis but the ultrasound could be useful. (bvsalud.org)
Surgery1
- Vacuum erectile devices (VEDs) -or penis pumps-are an effective treatment for ED that does not involve medication or surgery. (healthnews.com)
Tissue3
- The internal structures of the penis consist mainly of cavernous, erectile tissue, which is a collection of blood sinusoids separated by sheets of connective tissue (trabeculae). (wikipedia.org)
- Peyronie's disease is a condition in which segments of flat scar tissue (called plaques) form under the skin of the penis. (emedicinehealth.com)
- The plaque, a flat plate of scar tissue, develops on the top or bottom side of the penis inside a thick membrane called the tunica albuginea, which envelopes the erectile tissues. (emedicinehealth.com)
Unlike1
- Unlike many ED treatments, penis pumps are effective for treating ED due to nerve damage. (healthnews.com)
Relation1
- In relation to penis size , not so much. (healthline.com)
Male8
- PL: penises or penes) is the primary sexual organ that male animals use to inseminate females (or hermaphrodites) during copulation. (wikipedia.org)
- Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. (wikipedia.org)
- Male and female emus are similar in appearance, although the male's penis can become visible when it defecates. (wikipedia.org)
- The male tinamou has a corkscrew shaped penis, similar to those of the ratites and to the hemipenis of some reptiles. (wikipedia.org)
- The penis is the male organ used for urination and sexual intercourse. (medlineplus.gov)
- Welcome to TRUE PENIS ENHANCER, your trusted source for the latest and most reputable male enhancement products. (truepenisenhancer.com)
- The character of the other party is not his type at male enhancers reviews recovering, he immediately began to think about the possible benefits in his mind Even I know very little Brian Redban penis pill if there is no big meal, do you want dessert He put his hand on the table and tapped lightly twice. (jewishledger.com)
- Male penis size is well-charted terrain in studies, Herbenick said. (nbcnews.com)
Results1
- The study, published online July 10 in the Journal of Sexual Medicine, is relatively consistent with the results of prior surveys of penis size. (nbcnews.com)
Long3
- She told Steppin' Out magazine that ex-boyfriend Jon Gosselin's penis is 'three inches' long. (gawker.com)
- He resigned and compiled himself into a good seedling New that had been soaked in the school library all day long Penis After half a day, my parents finally Growth collected the New Penis Growth money in doubt, but my dad still threatened me. (emailarms.com)
- occurs when long-term (chronic) inflammation causes the skin near the tip of the penis to harden and turn white. (msdmanuals.com)
Blood5
- A bird penis is different in structure from mammal penises, being an erectile expansion of the cloacal wall and being erected by lymph, not blood. (wikipedia.org)
- Priapism occurs in several conditions that interfere with the blood flow to the penis or blood drainage from the penis. (medicinenet.com)
- In this form, too much blood flows into the penis. (medicinenet.com)
- Blood is drained from the penis using a 16 or 18 gauge needle and syringe. (medicinenet.com)
- Penis pumps, or VEDs, are an effective treatment for ED. VEDs can be an ideal ED treatment for men who have ED caused by nerve damage or poor blood flow, those who cannot take oral ED medications, and men who prefer non-invasive ED treatments. (healthnews.com)
Sexual1
- In many cases, the pain decreases over time, but the bend in the penis may remain a problem, making sexual intercourse difficult. (emedicinehealth.com)
Types2
- Penis pumps have several advantages over other types of ED treatment. (healthnews.com)
- Overall, however, penis pumps are an excellent drug-free and non-invasive treatment for many types of ED that can be used along with other ED treatments. (healthnews.com)
Time2
- But in the interest of continuing to chronicle the saga of my prostate cancer - for the benefit, I hope, of those who follow - the time has come to write about my penis. (buzzmachine.com)
- For instance, such minor genetic shifts have made human penises smoother and simpler over time, according to the study, which appears tomorrow in the journal Nature . (nationalgeographic.com)
Made2
- Men have lost the DNA code that once made human penises spiny, according to a new analysis of the human genome . (nationalgeographic.com)
- We're not gonna lie, the coloration of the Penis Bottle Opener made us a little uneasy at first. (bachelorette.com)
Size9
- As a general rule, a mammal's penis is proportional to its body size, but this varies greatly between species - even between closely related ones. (wikipedia.org)
- In comparison, the human penis is larger than that of any other primate, both in proportion to body size and in absolute terms. (wikipedia.org)
- Penis size has been the subject of dozens of studies, as well as countless urban legends, myths and spam emails. (nbcnews.com)
- But whether penis size truly matters to a man's sex partner is up for debate. (nbcnews.com)
- This indicates that many men suffer from penis size complexes. (healthstatus.com)
- Many men are not happy with the size of their penis. (healthstatus.com)
- All these make men aggressively look for ways and means to increase the size of their penis. (healthstatus.com)
- Even someone who has a seven inch penis would still want to increase their penis size further. (healthstatus.com)
- You will be able to increase the size of the penis and gain your self-esteem back. (healthstatus.com)
Make2
- Constriction from the penis ring can prevent ejaculation and may make it more difficult to achieve orgasm. (healthnews.com)
- To expose our clinical experience in the management of the penis fracture and make a literature review about this topic. (bvsalud.org)
Makes1
- The Penis Bottle Opener makes a one-of-a-kind party favor to give your bachelorette party guests, and should help you get drunk at the bachelorette party too! (bachelorette.com)
Comparison1
- Management of Penis Fracture: Clinical Cases Treated in Our Center and Comparison with Literature. (bvsalud.org)
Partner3
- Better known as "cowgirl," this one begins with the partner with the penis lying on their back while the other partner climbs on facing them. (healthline.com)
- This allows for the deepest penetration and the partner on top can ensure the penis stays in for the whole ride by using a grinding or side-to-side motion instead of just moving up and down. (healthline.com)
- For this one, the partner with the penis sits on the end of the bed or a chair. (healthline.com)
Includes2
- really Penis includes food and bag is it covered? (emailarms.com)
- Includes penis-to-penis subsite inoculations. (cdc.gov)
Skin3
- Hard she looked at Lin Fang carefully Indeed Little Bumps she was shocked to see the Under portrait of Skin Lin On Fang in the box Penis a thousand years ago! (emailarms.com)
- Various abnormalities can affect the skin of the penis. (msdmanuals.com)
- Some are bodywide skin disorders that affect the penis as well as other parts of the skin. (msdmanuals.com)