The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
Cancers or tumors of the PENIS or of its component tissues.
The state of the PENIS when the erectile tissue becomes filled or swollen (tumid) with BLOOD and causes the penis to become rigid and elevated. It is a complex process involving CENTRAL NERVOUS SYSTEM; PERIPHERAL NERVOUS SYSTEMS; HORMONES; SMOOTH MUSCLES; and vascular functions.
The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction.
An erectile structure homologous with the penis, situated beneath the anterior labial commissure, partially hidden between the anterior ends of the labia minora.
A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
Inflammation of the head of the PENIS, glans penis.
A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.
A cutaneous pouch of skin containing the testicles and spermatic cords.
Rigid, semi-rigid, or inflatable cylindric hydraulic devices, with either combined or separate reservoir and pumping systems, implanted for the surgical treatment of organic ERECTILE DYSFUNCTION.
Surgery performed on the male genitalia.
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
Excision of the prepuce of the penis (FORESKIN) or part of it.
MYCOBACTERIUM infections of the male reproductive tract (GENITALIA, MALE).
A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
Sexual union of a male and a female in non-human species.
Surgical insertion of cylindric hydraulic devices for the treatment of organic ERECTILE DYSFUNCTION.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
The external and internal organs related to reproduction.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Arthropods of the class ARACHNIDA, order Araneae. Except for mites and ticks, spiders constitute the largest order of arachnids, with approximately 37,000 species having been described. The majority of spiders are harmless, although some species can be regarded as moderately harmful since their bites can lead to quite severe local symptoms. (From Barnes, Invertebrate Zoology, 5th ed, p508; Smith, Insects and Other Arthropods of Medical Importance, 1973, pp424-430)
A plant genus of the family PRIMULACEAE. It can cause CONTACT DERMATITIS. SAPONINS have been identified in the root.
An order of fish with eight families and numerous species of both egg-laying and livebearing fish. Families include Cyprinodontidae (egg-laying KILLIFISHES;), FUNDULIDAEl; (topminnows), Goodeidae (Mexican livebearers), Jenynsiidae (jenynsiids), Poeciliidae (livebearers), Profundulidae (Middle American killifishes), Aplocheilidae, and Rivulidae (rivulines). In the family Poeciliidae, the guppy and molly belong to the genus POECILIA.
The deposit of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
A class in the phylum MOLLUSCA comprised of SQUID; CUTTLEFISH; OCTOPUS; and NAUTILUS. These marine animals are the most highly organized of all the mollusks.
Pathological processes involving the PENIS or its component tissues.
The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.
Literary or artistic items having an erotic theme. It refers especially to books treating sexual love in a sensuous or voluptuous manner. (Webster, 3d ed)
Cortical vigilance or readiness of tone, presumed to be in response to sensory stimulation via the reticular activating system.
An arthropod subclass (Xiphosura) comprising the North American (Limulus) and Asiatic (Tachypleus) genera of horseshoe crabs.
Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.
The techniques used to draw blood from a vein for diagnostic purposes or for treatment of certain blood disorders such as erythrocytosis, hemochromatosis, polycythemia vera, and porphyria cutanea tarda.
A space in which the pressure is far below atmospheric pressure so that the remaining gases do not affect processes being carried on in the space.
A belief or practice which lacks adequate basis for proof; an embodiment of fear of the unknown, magic, and ignorance.
Decisions made by the United States Supreme Court.
The process of making a selective intellectual judgment when presented with several complex alternatives consisting of several variables, and usually defining a course of action or an idea.
The region of southwest Asia and northeastern Africa usually considered as extending from Libya on the west to Afghanistan on the east. (From Webster's New Geographical Dictionary, 1988)
The transference of a kidney from one human or animal to another.
The transference of a part of or an entire liver from one human or animal to another.
A weapon designed to explode when deployed. It frequently refers to a hollow case filled with EXPLOSIVE AGENTS.
Women licensed to practice medicine.
Prejudice or discrimination based on gender or behavior or attitudes that foster stereotyped social roles based on gender.
The distal part of the arm beyond the wrist in humans and primates, that includes the palm, fingers, and thumb.
Achievement of full sexual capacity in animals and in humans.
A period in the human life in which the development of the hypothalamic-pituitary-gonadal system takes place and reaches full maturity. The onset of synchronized endocrine events in puberty lead to the capacity for reproduction (FERTILITY), development of secondary SEX CHARACTERISTICS, and other changes seen in ADOLESCENT DEVELOPMENT.

Nitric oxide release in penile corpora cavernosa in a rat model of erection. (1/1135)

1. Nitric oxide (NO) levels were measured in the corpus cavernosum of urethane-anaesthetized rats by using differential normal pulse voltammetry with carbon fibre microelectrodes coated with a polymeric porphyrin and a cation exchanger (Nafion). A NO oxidation peak could be recorded at 650 mV vs. a Ag-AgCl reference electrode every 100 s. 2. This NO signal was greatly decreased by the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME), given by local and systemic routes, and enhanced by the NO precursor L-arginine. Treatment with L-arginine reversed the effect of L-NAME on the NO peak. 3. Both the NO signal and the intracavernosal pressure (ICP) were increased by electrical stimulation of cavernosal nerves (ESCN). However, the rise in the NO levels long outlived the rapid return to baseline of the ICP values at the end of nerve stimulation. 4. The ICP and the NO responses to ESCN were suppressed by local and systemic injections of L-NAME. Subsequent treatment with L-arginine of L-NAME-treated animals restored the NO signal to basal levels and the NO response to ESCN. The ICP response to ESCN was restored only in part by L-arginine. 5. The observed temporal dissociation between the NO and ICP responses could be accounted for by several factors, including the buffering of NO by the blood filling the cavernosal spaces during erection. 6. These findings indicate that an increased production of NO in the corpora cavernosa is necessary but not sufficient for maintaining penile erection and suggest a complex modulation of the NO-cGMP-cavernosal smooth muscle relaxation cascade.  (+info)

Concordant induction of cyclin E and p21cip1 in differentiated keratinocytes by the human papillomavirus E7 protein inhibits cellular and viral DNA synthesis. (2/1135)

Productive infections by human papillomaviruses (HPVs) occur only in differentiated keratinocytes in squamous epithelia in which the HPV E7 protein reactivates the host DNA replication machinery to support viral DNA replication. In a fraction of the differentiated keratinocytes, E7 also posttranscriptionally induces p21Cip1, which is distributed in a mutually exclusive manner with unscheduled cellular DNA synthesis. In this study, double immunofluorescence labeling unexpectedly revealed that E7 caused a concordant accumulation of both cyclin E and p21Cip1 to high levels in patient papillomas and in organotypic cultures of primary human keratinocytes. The induction of cyclin E is mutually exclusive with unscheduled cellular DNA synthesis or abundant viral DNA. These novel virus-host interactions in differentiated keratinocytes are in contrast to previous observations made in submerged proliferating cultures, in which HPV E7 induces cyclin E and overcomes p21Cip1 inhibition of S-phase entry. We propose that an appropriately timed induction of cyclin E/cyclin-dependent kinase 2 by HPV E7 in postmitotic cells enables S-phase reentry and HPV DNA amplification, whereas prematurely induced cyclin E stabilizes p21Cip1 protein, which then inhibits cyclin E/cyclin-dependent kinase 2. Consequently, cyclin E and p21Cip1 both fail to turn over, and DNA synthesis does not occur.  (+info)

Determination of intrapenial blood volume using 99mTc-labeled autologous red blood cells. (3/1135)

In 17 impotent patients, radioisotope penography was performed using 99mTc-red blood cells (the patient's own red blood cells labeled with 99mTc) for the quantitative analysis of intrapenial blood volume. A visual sexual stimulation (VSS) was given to the patient after injecting the 99mTc-red blood cells. Patients showing a complete erection had their intrapenial blood volumes 4.2-11.2 times greater than before VSS (mean increase, 8.0 times). In cases of incomplete erection after VSS the intrapenial blood volumes were 3.3-7.0 times greater than before VSS (mean increase, 4.9 times). In cases showing a gentle rise in their penogram curves without evidence of an erection, intrapenial blood volumes after VSS were 2.0-3.3 times those before VSS (mean increaae, 2.9 times). By contrast, in cases showing no response to the VSS or no rise in penogram curve, post-VSS increases in intrapenial pool of blood were very slight, slight, only 1.4-1.7 times the original volume of blood.  (+info)

Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture. (4/1135)

Glutathione S-transferase (GST) M1 is a member of the GST mu family of cytosolic enzymes that have been hypothesized to catalyze the conjugation of glutathione to a large number of hydrophobic substances, including carcinogens such as polynuclear aromatic hydrocarbons present in tobacco smoke, leading to their excretion. Epidemiologic and experimental evidence suggests that the risk of cervical cancer is related to both human papillomavirus (HPV) infection and cigarette smoking. We compared the enzymatic activities and mRNA levels of GSTs in GSTM1-positive human cervical keratinocytes (HCKs) that had been transfected with HPV16 with those in the parental cells. The GSTM1 activity toward the substrate trans-stilbene oxide was 5- to 7-fold lower than in the parental cells. The relative mRNA level in HCK transfected with HPV16 E6/E7, as quantified by reverse transcriptase-polymerase chain reaction (RT-PCR) with normalization against endogenous glyceraldehyde-3-phosphate dehydrogenase (GAPDH) expression, was 6% that of the parental cells. It was 16 and 82%, respectively, in cells that were transfected with HPV16 E6 alone or HPV16 E7 alone. When quantified by competitive RT-PCR using an exogenous nuclease-resistant synthetic cyclophilin RNA transcript as control, the mRNA level in HCK transfected with HPV16 E6 was approximately 10-fold lower that that in the parental cells. It was approximately 5- to 7-fold lower in the HPV16 E7 or HPV16 E6/E7 cells. Our results suggest that viral infections, through the modulation of cellular xenobiotic-metabolizing enzymes, may play a role in the ability of cells to handle environmental carcinogens.  (+info)

Direct and indirect modulation of ornithine decarboxylase and cyclooxygenase by UVB radiation in human skin cells. (5/1135)

Exposure to solar ultraviolet (UV) B radiation is responsible for skin inflammation and tumour progression. Cyclooxygenase and ornithine decarboxylase are believed to be involved in such processes since they participate in the synthesis of mediators of inflammation and cell differentiation, respectively. We have investigated the in vitro modulation of expression of such genes by UVB radiation in different skin cell lines. We have observed that accumulation of ornithine decarboxylase mRNA is unaffected by even high UVB doses in both human epidermal keratinocytes and dermal fibroblasts, whereas cyclooxygenase-2 levels were significantly up-regulated by low UVB doses in KB human epidermoid keratinocytes. Depletion of total intracellular glutathione levels in KB cells amplified the activation, revealing a role for an oxidative component of UVB in modulating cyclooxygenase gene expression. Transfer of medium from UVB irradiated keratinocytes to fibroblasts resulted in a significant activation of cyclooxygenase expression and activity, while ornithine decarboxylase levels were unaffected. We conclude that UVB radiation can activate cyclooxygenase gene expression in human skin cells both by direct activation pathways or indirectly by inducing a paracrine mechanism.  (+info)

Effects of hydroxocobalamin and carboxy-PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles. (6/1135)

The effects of carboxy-PTIO and hydroxocobalamin were studied on nitrergic transmission in anococcygeus and retractor penis muscles taken during post mortem examination from young male pigs. In both muscles under resting conditions, electrical field stimulation (EFS) caused contractions that were sensitive to tetrodotoxin (1 microM) and were greatly inhibited by prazosin (1 microM) and guanethidine (10-30 microM), but were not significantly affected by atropine (1 microM). In the anococcygeus muscle, but not in the retractor penis muscle, guanethidine produced a prolonged contraction. After tone was raised by guanethidine in the anococcygeus or by phenylephrine (1 microM) in the presence of guanethidine in the retractor penis, EFS caused tetrodotoxin-sensitive relaxations. The EFS-induced relaxations were abolished by the NO synthase inhibitor N(G)-L-nitro-arginine methyl ester (L-NAME; 100 microM) and its effect was partly overcome by L-arginine (1 mM), indicating it was mediated by nitrergic nerves. Carboxy-PTIO (0.1-1 mM) had no significant effect in reducing stimulation-induced nitrergic relaxations in either muscle. However, hydroxocobalamin (0.1-1 mM) caused concentration-dependent reductions of nitrergic relaxations in both muscles. Relaxations to exogenous nitric oxide (1 microM) in both muscles were abolished by carboxy-PTIO (0.3 mM) and hydroxocobalamin (0.1 mM). There were no differences in reactivity to carboxy-PTIO or hydroxocobalamin between anococcygeus and retractor penis muscles from the same species (pig). The finding also confirms earlier observations that the nitrergic transmitter is generally resistant to the NO-scavenger carboxy-PTIO.  (+info)

Design and evaluation of nitrosylated alpha-adrenergic receptor antagonists as potential agents for the treatment of impotence. (7/1135)

We designed and evaluated a new class of molecules, nitrosylated alpha-adrenergic receptor antagonists, as potential agents for the treatment of impotence. In in vitro studies with human and rabbit corpus cavernosum strips in organ chambers, the alpha-adrenergic receptor antagonists (alpha-ARAs) moxisylyte and yohimbine and their corresponding nitrosylated compounds, SNO-moxisylyte (NMI-221) and SNO-yohimbine (NMI-187), concentration-dependently relaxed endothelin-induced contraction. The nitrosylated compounds were significantly more potent than the parent alpha-ARA. In human tissues, the specific phosphodiesterase type 5 inhibitor zaprinast potentiated the relaxing effects of the nitrosylated compounds. Only nitrosylated compounds induced accumulation of cyclic GMP in rabbit corpus cavernosum strips. Yohimbine and NMI-187 demonstrated a potent alpha2-blocking activity, with no significant differences in pA2 values (8.9 versus 8.2, respectively). Moxisylyte and NMI-221 showed moderate potency in antagonizing phenylephrine contraction, with comparable pA2 values for both molecules (6.5 versus 6.6, respectively). alpha-Adrenergic receptor-binding studies showed similar binding affinities for the alpha-ARA and their corresponding nitrosylated compounds. In vivo, intracavernosal injection of nitrosylated molecules caused greater increases in intracavernosal pressure (NMI-221 versus moxisylyte) that were more long lasting than those of moxisylyte or yohimbine. There were no significant differences between nitrosylated and non-nitrosylated compounds in the magnitude of systemic mean arterial pressure decrease after intracavernosal injection. alpha-ARA and the nitrosylated compounds showed no pain-inducing activity as evaluated with the paw-lick model in mice. In summary, nitrosylated alpha-ARA have the dual functionalities of nitric oxide donors and alpha-ARA. These drugs induced penile erection in animals, suggesting their possible therapeutic value as agents for the local pharmacological treatment of impotence.  (+info)

NO synthase in cholinergic nerves and NO-induced relaxation in the rat isolated corpus cavernosum. (8/1135)

1. In the rat corpus cavernosum (CC), the distribution of immunoreactivity for neuronal and endothelial NO synthase (nNOS and eNOS), and the pattern of NOS-immunoreactive (-IR) nerves in relation to some other nerve populations, were investigated. Cholinergic nerves were specifically immunolabelled with antibodies to the vesicular acetylcholine transporter protein (VAChT). 2. In the smooth muscle septa surrounding the cavernous spaces, and around the central and helicine arteries, the numbers of PGP- and tyrosine hydroxylase (TH)-IR terminals were large, whereas neuropeptide Y (NPY)-, VAChT-, nNOS-, and vasoactive intestinal polypeptide (VIP)-IR terminals were found in few to moderate numbers. 3. Double immunolabelling revealed that VAChT- and nNOS-IR terminals, VAChT- and VIP-IR terminals, nNOS-IR and VIP-IR terminals, and TH- and NPY-IR terminals showed coinciding profiles, and co-existence was verified by confocal laser scanning microscopy. TH immunoreactivity was not found in VAChT-, nNOS-, or VIP-IR nerve fibres or terminals. 4. An isolated strip preparation of the rat CC was developed, and characterized. In this preparation, cumulative addition of NO to noradrenaline (NA)-contracted strips, produced concentration-dependent, rapid, and almost complete relaxations. Electrical field stimulation of endothelin-1-contracted preparations produced frequency-dependent responses: a contractile twitch followed by a fast relaxant response. After cessation of stimulation, there was a slow relaxant phase. Inhibition of NO synthesis, or blockade of guanylate cyclase, abolished the first relaxant phase, whereas the second relaxation was unaffected. 5. The results suggest that in the rat CC, nNOS, VAChT- and VIP-immunoreactivities can be found in the same parasympathetic cholinergic neurons. Inhibitory neurotransmission involves activation of the NO-system, and the release of other, as yet unknown, transmitters.  (+info)

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TY - JOUR. T1 - Characterization of nitroglycerine induced relaxation in human corpus cavernosum smooth muscle. T2 - Implications to erectile physiology and dysfunction. AU - Christ, G. J.. AU - Kim, D. C.. AU - Taub, H. C.. AU - Gondre, C. M.. AU - Melman, A.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - The importance of the nitric oxide - guanylate cyclase - cGMP system in modulating corporal smooth muscle tone and penile erection has been amply demonstrated. The goal of these studies was to evaluate the possibility that age- or disease-related alterations in human corporal smooth muscle responsivity to activation of this pathway might play a role in the etiology of erectile dysfunction. Thus, we utilized a previously described heuristic model to assess the kinetic and steady-state characteristics of relaxation of precontracted isolated corporal tissue strips elicited by nitroglycerine (NTG). Studies were conducted on corporal tissue strips excised from 26 patients with organic erectile dysfunction, ...
Definition of corpus cavernosum penis rupture in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is corpus cavernosum penis rupture? Meaning of corpus cavernosum penis rupture as a finance term. What does corpus cavernosum penis rupture mean in finance?
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The glans penis is the expanded cap of the corpus spongiosum. It is moulded on the rounded ends of the corpora cavernosa penis, extending farther on their upper than on their lower surfaces. At the summit of the glans is the slit-like vertical external urethral orifice. The circumference of the base of the glans forms a rounded projecting border, the corona glandis, overhanging a deep retroglandular sulcus (the coronal sulcus), behind which is the neck of the penis. The proportional size of the glans penis can vary greatly. On some penises it is much wider in circumference than the shaft, giving the penis a mushroom-like appearance, and on others it is narrower and more akin to a probe in shape.[citation needed] The soft cushiony texture of the glans is intended to absorb impact during rigorous instances of copulation.[2]. The foreskin maintains the mucosa in a moist environment.[3] Circumcised penises have a glans which is permanently exposed and dry. Several studies have suggested the glans is ...
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OBJECTIVE: To explore the diagnostic value of the nerve conduction study in the dorsal nerve of penis before and after erection. METHOD: Nineteen subjects with a confirmed psychogenic impotence were studied for the superficial peroneal and sural sensory nerve conductions, bulbocavernous reflexes (BCR), tibial and pudendal somatosensory evoked potentials (SEP), and conduction studies of the dorsal nerve of penis. Sixteen subjects with normal findings had repeat studies after an injection of Prostaglandin E1. RESULTS: Erection helped to obtain a dorsal penile sensory potentials in 18.8% of the 16 subjects. The mean conduction velocity of the dorsal nerve of penis increased significantly from 33.8+/-9.3 m/sec to 48.4+/-12.8 m/sec. The mean sensory amplitude of the dorsal nerve of penis increased significantly from 1.7+/-1.0 microvolt to 2.8+/-1.4 microvolt. There was no significant difference in the BCR latency and the pudendal SEP (latency and amplitude) before and after erection. CONCLUSION: ...
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Erectile tissue is tissue in the body with numerous vascular spaces that may become engorged with blood. However, tissue that is devoid of or otherwise lacking erectile tissue (such as the labia minora, the vestibule/vagina and the urethra) may also be described as engorging with blood, often with regard to sexual arousal. Erectile tissue exists in places such as the corpora cavernosa of the penis, and in the clitoris or in the bulbs of vestibule. During erection, the corpora cavernosa will become engorged with arterial blood, a process called tumescence. This may result from any of various physiological stimuli, also known as sexual arousal. The corpus spongiosum is a single tubular structure located just below the corpora cavernosa. This may also become slightly engorged with blood, but less so than the corpora cavernosa. Erectile tissue is also found in the nose (turbinates), ear, urethral sponge and perineal sponge. The erection of nipples is not due to erectile tissue, but rather due to the ...
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TY - JOUR. T1 - Smooth muscle myosin expression, isoform composition, and functional activities in rat corpus cavernosum altered by the streptozotocin-induced type 1 diabetes. AU - Zhang, Xinhua. AU - Kanika, Nirmala D.. AU - Melman, Arnold. AU - DiSanto, Michael E.. PY - 2012/1. Y1 - 2012/1. N2 - Diabetes mellitus (DM) is a quite common chronic disease, and the prevalence of erectile dysfunction (ED) is three times higher in this large population. Although diabetes-related ED has been studied extensively, the actin-myosin contractile apparatus was not examined. The mRNAs encoding smooth muscle myosin (SMM) heavy chains (MHC) and essential light chains (LC 17) exist as several different alternatively spliced isoforms with distinct contractile properties. Recently, we provided novel data that blebbistatin (BLEB), a specific myosin II inhibitor, potently relaxed corpus cavernosum smooth muscle (CCSM). In this study, we examine whether diabetes alters SMM expression, alternative splicing, and/or ...
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Circumcision Removes the Most Sensitive Parts of the PenisA sensitivity study of the adult penis in circumcised and uncircumcised men shows that the uncircumcised penis is significantly more sensitive. The most sensitive location on the circumcised penis is the circumcision scar on the ventral surface. Five locations on the uncircumcised penis that are routinely removed at circumcision are significantly more sensitive than the most sensitive location on the circumcised penis.In addition, the glans (head) of the circumcised penis is less sensitive to fine touch than the glans of the uncircumcised penis. The tip of the foreskin is the most sensitive region of the uncircumcised penis, and it is significantly more sensitive than the most sensitive area of the circumcised penis. Circumcision removes the most sensitive parts of the penis. This study presents the first extensive testing of fine touch pressure thresholds of the adult penis. The monofiliment testing instruments are calibrated and have ...
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We recently found that the oxytocin receptor (OTR) is expressed in the human and rabbit corpus cavernosum and mediates contractility in vitro. The present study extended our investigations to the rat, and explored whether OTR regulates penile detumescence in vivo. Real-time RT-PCR quantitatively characterized the distribution of OTR mRNA in the male genital tract. Specific transcripts for OTR were expressed in all the tissues investigated. Penile expression of OTR was comparable to that observed in testis and prostate. Western blot analysis detected a single band of the expected molecular mass for OTR in all tissues examined, including rat penis. Expression of OTR protein in rat penile extracts was further confirmed by binding studies, using the OTR selective radiolabeled ligand 125I-OTA (K(d) = 17 +/- 6.5 pM, B(max)=15.7 +/- 5 fmoles/mg protein). OTR was immunolocalized to the endothelial and smooth muscle compartments of cavernous spaces and blood vessels. In rat corpus cavernosum strips, ...
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Ergo, the sexual stimulation, which can be tactile (reflex) or psychogenic/psychologic, creates electrical urges across the nerves going to the penis and causes the nerves to release nitric oxide (NO), which, in turn, escalates the generation of cyclic GMP (cGMP) in the clean muscle cells of the corpora cavernosa. The cGMP causes the rest of smooth muscles of corpora cavernosa, letting a rapid blood flowing into the penis (the blood floods the corpora cavernosa, making the penis bigger, harder and thicker). The consequential pressure compresses the veins in the tunica albuginea, helping to trap the body in the corpora cavernosa, therefore sustaining erection. Erection is changed when cGMP levels in the corpora cavernosa drop, allowing the clean muscles of the corpora cavernosa to agreement, ceasing the inflow of blood and starting veins that strain body from the penis. The degrees of the cGMP in the corpora cavernosa fall since its inactivated by a molecule, named phosphodiesterase type 5 ...
Erectile tissue forms cylindrical bodies, which are located along the reproductive organ. The two corpora cavernosa are located on the sides and at the top of the penis. Corpus spongiosum is located below and between the corpora cavernosa.. The erectile tissue is composed of many small and interconnected cavities. In certain circumstances, such as in response to sexual stimulation, the erectile tissue cavities are engorged with blood.. Due to the sexual arousal and the increased blood flow, the primary sex organ increases in size, and becomes firm and erect. Man has the possibility to start and complete a sexual intercourse.. It should be noted that the erectile tissue contains major part of the blood in erection period. Urethra, skin, arteries, and other parts of the male reproductive organ are elastic and easily grow in size.. Achieving an erection that is sufficient for a having a sexual intercourse is the only basic function of corpora cavernosa. Therefore, most of blood (approximately 90%) ...
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Some researchers believe Peyronie disease develops after an injury that causes bleeding inside the penis. This could explain cases of Peyronie that develop quickly. But it does not explain why most cases develop slowly, or what causes the disease after no clear injury. Most researchers believe that genetics or the environment may play a role. Men with certain connective tissue disorders and men who have a close family member with Peyronie disease are at greater risk. And certain health conditions such as diabetes or tobacco use may also contribute to its development. If the disease heals within a year or so, the plaque usually does not get worse. But when the disease lasts for years, the plaque often becomes a tough, fibrous tissue, and calcium deposits may form. The plaque in Peyronie disease is not cancer.. ...
How does an erection actually happen? Well the simple version is that blood enters the penis and the penis then becomes erect. In more medical jargon - the blood vessels of the corpora cavernosa relax and open up, blood rushes in through the cavernosus arteries to fill them. The blood then gets trapped under high pressure creating an erection.. An erection begins with sensory and mental stimulation. During sexual arousal, nerve messages begin to stimulate the penis. Impulses from the brain and local nerves cause the muscles of the corpora cavernosa to relax, allowing blood to flow in and fill the open spaces. The blood creates pressure in the corpora cavernosa, making the penis expand and creating an erection. The tunica albuginea (the membrane surrounding the corpora cavernosa ), helps to trap the blood in the corpora cavernosa, thereby sustaining erection. Erection is reversed when muscles in the penis contract, stopping the inflow of blood and opening outflow channels.. Below is a video from ...
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Penoscrotale Hypospadias vs. Burried Penis (Micropenis). Penoscrotale Hypospadias vs. Burried Penis (Micropenis) Left picture: Here, a severe type of hypospadias is present, a so-called penoscrotal hypospadias. Right picture: The diagnosis is a so-called burried penis, which means a penis that seems to be a micropenis due to or hidden by obesity. Left picture: Only a precise examination yields informations on the actual pathology and allows to discard the first impression of intersexual external genitals. In the additional figure at the bottom the penis is elevated, and the scrotum unfolded. In both scrotal halves a testis of normal size is visible and palpable. The penis has a ventral curvature, its ventrally split foreskin is adherent to the right circumference of the glans, and the urethral orifice lies at the beginning of the bifid (ventrally split) scrotum. Right picture: In the additional picture the suprapubic fatty tissue has been moved to the top, revealing a developed penis ...
Hydrogen sulfide (H2S) is synthesized by 2 enzymes, cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE). L-Cysteine (L-Cys) acts as a natural substrate for the synthesis of H2S. Human penile tissue possesses both CBS and CSE, and tissue homogenates efficiently convert L-Cys to H2S. CBS and CSE are localized in the muscular trabeculae and the smooth-muscle component of the penile artery, whereas CSE but not CBS is also expressed in peripheral nerves. Exogenous H2S [sodium hydrogen sulfide (NaHS)] or L-Cys causes a concentration-dependent relaxation of strips of human corpus cavernosum. L-Cys relaxation is inhibited by the CBS inhibitor, aminoxyacetic acid (AOAA). Electrical field stimulation of human penile tissue, under resting conditions, causes an increase in tension that is significantly potentiated by either propargylglycine (PAG; CSE inhibitor) or AOAA. In rats, NaHS and L-Cys promote penile erection, and the response to L-Cys is blocked by PAG. Our data demonstrate that ...
Learn what causes curvature of the penis and how it is treated here. Not all men have a straight penis, but that doesnt mean it is curved enough to be considered a true curvature. True curvature of the penis happens during an erection, and can involve narrowing of the penis during an erection, and painful erections.. Peyronies disease. This disease affects men who are over 40 years old. In this disease, scar tissue forms under the layer of skin on the penis. This scar tissue causes the penis to curve during an erection because it is bound to the skin. Peyronies disease generally occurs after an injury to the penis. Forceful or vigorous sexual intercourse can cause the shaft to bend, and cause scar tissue to form. Some procedures such as catheter placement or prostate removal can also cause injury which makes this scar tissue form. Deficiency in Vitamin E has also been linked to this disease. Diseases such as diabetes can also cause Peyronies disease because diabetes can damage the blood ...
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The reasons behind Peyronies Disease are currently obscure, and it can be said that medical science is still unclear as to the causes. Similar conditions of the hands are frequently found in sufferers of Peyronies Disease, and almost 1 in 3 men who suffer from Peyronies Disease can be affected by conditions such as Dupuytrens Contracture. Studies have also shown that middle-aged Caucasian men are more likely to suffer from Peyronies Disease. Both of these facts have led some researchers to believe Peyronies Disease has a genetic element.. However, more research has shown that the legions and hardening of the penis, which ultimately causes curvature, can be traced to traumatic injury. A large number of Peyronies Disease sufferers can trace their disease to an event that caused damage to their penis; most commonly through sexual intercourse. It is conjectured that most forms of Peyronies Disease are in fact initially caused by this trauma, even if the sufferer was unaware of the damage ...
Purpose: We investigated penile sensory levels in patients with primary premature ejaculation to determine whether there is an etiological basis for this condition. Materials and Methods: Penile biothesiometry was performed in 120 patients with primary premature ejaculation without erectile dysfunction and neurological deficit, and in 66 normal potent male volunteers. Vibratory thresholds were recorded at the glans penis, penile shaft, scrotum and index finger using a biothesiometer. Results: On the glans penis and penile shaft the values in patients with premature ejaculation were significantly less than those in normal potent men (p ,0.001). In normal potent men an age dependency of biothesiometric parameters was noted, with a significant increase in vibratory threshold at the glans penis and penile shaft in older patients. However, in patients with premature ejaculation there were consistently decreased values without age dependency at the glans penis and penile shaft (p ,0.05). Conclusions: ...
What is Peyronies disease? Peyronies disease is characterized by a plaque, or hard lump, that forms on the erection tissue of the penis. The plaque often begins as an inflammation that may develop into a fibrous tissue. Peyronies disease was first described in 1743 by a French surgeon, François de la Peyronie. It was classified as a form of impotence. However, now impotence is recognized as one factor associated with Peyronies disease, but it is not always present.
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Get the Facts about Peyronies Disease The Urology Care Foundation is getting the word out about Peyronies Disease. Talking to your doctor (as soon as you can) is crucial if you think you have it. As a starting point for learning about this disease, view 3 of our free educational resources: Peyronies Disease: What You Should Know (fact sheet) The Peyronies Disease Video The Peyronies Disease Infographic
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Penile erection is managed by two mechanisms: the reflex erection, which is achieved by directly touching the penile shaft, and the psychogenic erection, which is achieved by erotic or emotional stimuli. The former uses the peripheral nerves and the lower parts of the spinal cord, whereas the latter uses the limbic system of the brain. In both cases, an intact neural system is required for a successful and complete erection. Stimulation of the penile shaft by the nervous system leads to the secretion of nitric oxide (NO), which causes the relaxation of smooth muscles of corpora cavernosa (the main erectile tissue of penis), and subsequently penile erection. Additionally, adequate levels of testosterone (produced by the testes) and an intact pituitary gland are required for the development of a healthy erectile system. As can be understood from the mechanisms of a normal erection, impotence may develop due to hormonal deficiency, disorders of the neural system, lack of adequate penile blood ...
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The generation of nitric oxide (NO) in penile erectile tissue and the subsequent elevation of cyclic GMP (cGMP) levels are important for normal penile erection. Current treatments of erectile dysfunction elevate either cGMP levels by blocking cGMP degrading phosphodiesterase 5 or cyclic AMP (cAMP) levels by intrapenile injection of prostaglandin E1. The molecular target or targets of cGMP in erectile tissue and the role of cAMP for normal penile erection are not known. Herein, we report that mice lacking cGMP-dependent kinase I (cGKI) have a very low ability to reproduce and that their corpora cavernosa fail to relax on activation of the NO/cGMP signaling cascade. Elevation of cAMP by forskolin, however, induces similar relaxation in normal and cGKI-null corpus cavernosum. In addition, sperm derived from cGKI-null mice is normal, can undergo acrosomal reactions, and can efficiently fertilize eggs. Altogether, these data identify cGKI as the downstream target of cGMP in erectile tissue and ...
Rationale of combination therapy with antioxidants in medical management of Peyronies disease: results of clinical application Gianni Paulis,1,2 Andrea Paulis,3 Gennaro Romano,4 Davide Barletta,5 Andrea Fabiani6 1Department of Surgical Sciences, Andrology Center, Regina Apostolorum Hospital, Rome, Italy; 2Department of Uro-Andrology, Peyronies Disease Care Center, Rome, Italy; 3Section of Psycho-Sexology, Peyronies Disease Care Center, Rome, Italy; 4Department of Urologic Oncology, Section of Avellino, Italian League against Cancer, Avellino, Italy; 5Department of Urology, Andrology Center, San Matteo Hospital, Pavia, Italy; 6Department of Surgery, Section of Urology and Andrology, Macerata, Italy Abstract: Peyronies disease (PD) is a connective tissue disorder involving the tunica albuginea of the corpora cavernosa of the penis. We have published several studies describing a
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The purpose of this study was to report the outcomes of patients who underwent penile implantation with AMS 700 LGX inflatable penile prosthesis (IPP) in a single center by a single surgeon. A total of 342 patients with erectile dysfunction who underwent AMS 700 LGX IPP implantation between October 2014 and April 2016 were included in this study. All patients were evaluated using the International Index of Erectile Function questionnaire preoperatively and at 3, 6, and 12 months postoperatively. We also investigated the mean stretched flaccid penile length before and after surgery as well as the complications related to and the mechanical reliability of the IPP. The questionnaire scores at 12 months were statistically significantly higher than the baseline scores. The mean stretched flaccid penile length was 11.1 ± 0.8 cm at baseline and was longer at 3 (11.9 ± 0.9 cm, P | 0.001), 6 (12.0 ± 0.9 cm, P | 0.001), and 12 (12.2 ± 0.7 cm, P | 0.001) postoperatively. There were no intraoperative or
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Dorsal penile nerve block for rigid cystoscopy in men: study protocol for a randomized controlled trial. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Treatment of erectile dysfunction begins with non-surgical procedures. Patients suffering from erectile dysfunction often experience negative psychological side effects.
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In a previous post, we discussed penile pearly papules.. Lichen planus can also cause bumps on the penis. This condition is an inflammatory condition - NOT an STD.. Classical lichen planus is characterized by shiny, flat-topped, firm papules (bumps) varying from pin point size (guttate) to larger than a centimetre. They are a purple colour and often are crossed by fine white lines (called Wickhams striae). They may be close together or widespread, or grouped in lines (linear lichen planus) or rings (annular lichen planus). Linear lichen planus can be the result of scratching or injuring the skin. Although sometimes there are no symptoms, it is often very itchy.. Lichen planus may affect any area, but is most often seen on the front of the wrists, lower back, and ankles. They are also commonly found on the penis.. Sometimes it may be necessary to take a skin biopsy to confirm the diagnosis. One of the best treatments for lichen planus on the penis are injections with cortisone.. Tags: ...
The present invention relates to methods of relieving erectile impotence in a human male. The method comprises administering to the male an erectile impotence relieving amount of piperoxan and the compositions include an erectile impotence relieving amount of piperoxan or the pharmaceutically acceptable acid addition salts thereof optionally in combination with a pharmaceutically acceptable carrier.
This study aimed to investigate the effect of experimental periodontitis on rat penis. Eighteen Wistar rats underwent the placement of a cotton ligature around the first molars to induce periodontitis. It was confirmed that periodontitis was induced in the group with ligature due to the greater number of osteoclasts, decreased osteocytes, greater distance from the cementoenamel junction to the alveolar crest, increase in gingival swelling (p |0.05) and intense bone resorption. Furthermore, there was a higher average concentration of IL-6 in the gingival samples and of TNFα in the penile samples of the rats with ligature (p |0.05). There was a statistically significant thicker and smaller area of the dorsal penile arteries in the experimental group, as well as a smaller area of the vascular spaces of the corpora cavernosa (p|0.05). Therefore, the systemic inflammation caused by periodontal disease can be an important risk factor for erectile dysfunction.
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This page includes the following topics and synonyms: Peyronies Disease, Peyronies Syndrome, Plastic Induration of the penis, Induratio Penis Plastica, Strabismus Penis.
What is Erectile Dysfunction (ED) or impotence?. Erectile dysfunction is an inability to get or maintain an erection firm enough for a satisfactory sexual intercourse. Erectile dysfunction is a common problem in men with diabetes mellitus. This is a problem caused by poor blood sugar control over a long-time resulting in damages to nerves and blood vessels in the penis. This results in impaired blood flow to the penis which is one of most common causes of Erectile Dysfunction. About 35% to 75% of men with diabetes mellitus will experience at least some degree of erectile dysfunction or impotence during their lifetime. Diabetic patients develop erectile dysfunction 10 to 15 years earlier than non diabetic men. Age related diabetes and resulting erectile dysfunction is very common. Above the age of 50 years it is more likely to have difficulty with an erection. It occurs approximately in 50% to 60% of men with diabetes mellitus. Above the age of 70 there is about a 95% chances of having some ...
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Some researchers believe Peyronies disease develops following a trauma that causes bleeding inside the penis. This trauma may explain acute cases of Peyronies disease, but does not explain why most cases develop slowly, or what causes the disease after no apparent traumatic event.. Generally, when the disease heals within a year or so, the plaque does not advance beyond an initial inflammatory phase. However, when the disease lasts for years, the plaque often becomes a tough, fibrous tissue, and calcium deposits may form.. ...
Peyronies disease is the name for a sharp curve in the penis. In some men, Peyronies disease is a mild problem without symptoms.
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Getting too Excited: Dont get too excited and nervous in bed. Take deep breath and control your mind dont think about ejaculationKegel Exercise: kegel exercise strengthens poboccocygeus muscle. When you urinate try to hold the urine for seconds and let it flow. This is how you can find PC muscle. After you become familiar with the muscle you can easily put into practice the methods.. Squeezing: When you feel that you are about to ejaculate stop thrusting and squeeze below the head of the penis. Hold it for 30 seconds then the urge will go away this pushes blood out of the penis and delay ejaculation.Desensitizing Cream: Desensitizing cream decreases the sensation of penis which results in getting less aroused. Desensitizing cream help you last long in bed.Cock Ring: Cock ring is worn around the base of the penis to slow down the blood flow of penis this in turn holds back ejaculation. It traps blood inside the penis to keep the penis erected.Masturbating Before Sex: Masturbating before sex can ...
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Surgery is presented in the medical websites as the only sure and proven treatment option for PD. While drug options have variable success, surgical repair is currently regarded as the best way to remove the Peyronies scar.. Surgery is presented as the back-up choice to be used if PD leads to extreme pain, distortion and impotency. The American Academy of Family Physicians states, Despite numerous treatment options, there is no generally accepted, standard non-surgical treatment for Peyronies disease. With this statement they are confirming that there is one accepted treatment for PD - and it is surgical.. The person who reads this information is comforted by knowing that in the face of this terrible problem at least there is a surgical treatment to rely upon if all else fails. Surgery is presented almost as though if you gambled and lost with the wait-and-see option or with medication, you can always rely on good ol surgery to correct your problem.. In our opinion, while it is ...
The prostaglandin E1 is contained in a small suppository located at the tip of an applicator. You should urinate first as this lubricates the urethra and makes it easier to insert the applicator into the tip of the urethra (urethral meatus, the opening at the tip of the penis that urine passes through). A patient can release the suppository into urethra by gently wiggling the applicator and pressing the button at the end. Rubbing the penis allows the suppository to dissolve, and the prostaglandin is absorbed through the tissue of the urethra into the penis. It takes 15 to 30 minutes for this occur. Once into the penis, the prostaglandin causes increased blood flow into the penis. The prostaglandin can be present in the ejaculate, and thus doctors recommend that men use a condom when having intercourse with a pregnant partner. Men may need to use a condom if vaginal irritation occurs in female partner ...
Methods Inter-rater comparison of the responses on foreskin status and circumcision in a self-report questionnaire with the findings of a physical examination by an experienced well-trained urologist was performed for patients who visited a healthcare facility in Kanagawa, Japan. Foreskin status was defined using a five-point graphical scale based on the degree to which the foreskin covers the foreskin and the glans penis in a non-erectile condition: type 1, a fully exposed glans penis; types 2-4, the glans penis partly covered by the foreskin and type 5, phimosis. Linear weighted κ and per cent agreement were used to evaluate the reliability of responses. ...
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Unpaired penis as ancestral form[edit]. This theory proposes that the single unpaired penis is the ancestral state for amniotes ... Unlike squamata, however, their singular penis is four-headed. Many marsupials also exhibit bifurcated penises like squamata, ... Brennan, P.; Prum, R. (2011). "The erection mechanism of the ratite penis". Journal of Zoology. 286 (2): 140-144. doi:10.1111/j ... Among vertebrates, penises can be found in a variety of shapes, sizes and structures, such as the lymphatic erection mechanism ...
Mentula and verpa: the penis[edit]. Mentula[edit]. Mentula is the basic Latin word for penis. It is used 48 times in Martial, ... Verpa is also a basic Latin obscenity for "penis", in particular for a penis in an erect state with the glans bare,[10] as in ... "to excite the penis"), assuming an otherwise unattested meaning of "penis" for mās ("male"). The supporters of this view cite ... A third word for "penis" was mūtō, mūtōnis (or muttō, muttōnis). This is very rare and found only in one line of Horace and a ...
Penis[edit]. Main article: Human penis. The penis is the male intromittent organ. It has a long shaft and an enlarged bulbous- ... The penis is supplied by the pudendal artery. Scrotum[edit]. The scrotum is a pouch-like structure that hangs behind the penis ... Erection occurs because sinuses within the erectile tissue of the penis become filled with blood. The arteries of the penis are ... The main male sex organs are the penis and the testicles which produce semen and sperm, which, as part of sexual intercourse, ...
Allogeneic HSCT involves two people: the (healthy) donor and the (patient) recipient. Allogeneic HSC donors must have a tissue (HLA) type that matches the recipient. Matching is performed on the basis of variability at three or more loci of the HLA gene, and a perfect match at these loci is preferred. Even if there is a good match at these critical alleles, the recipient will require immunosuppressive medications to mitigate graft-versus-host disease. Allogeneic transplant donors may be related (usually a closely HLA matched sibling), syngeneic (a monozygotic or 'identical' twin of the patient - necessarily extremely rare since few patients have an identical twin, but offering a source of perfectly HLA matched stem cells) or unrelated (donor who is not related and found to have very close degree of HLA matching). Unrelated donors may be found through a registry of bone marrow donors such as the National Marrow Donor Program. People who would like to be tested for a specific family member or ...
A hand transplant was performed in Ecuador in 1964, but the patient suffered from transplant rejection after only two weeks due to the primitive nature of the immune-suppressing medications at that time. The first short-term success in human hand transplant occurred with New Zealander Clint Hallam who had lost his hand in an accident while in prison. The operation was performed on September 23, 1998 in Lyon, France by a team assembled from different countries around the world led by French Professor Jean-Michel Dubernard, including Prof Nadey Hakim, who represented the UK. A microsurgeon on the team, Earl Owen from Australia, was privy to the detailed basic research, much of it unpublished, that had been carefully gathered by the team[who?] in Louisville. After the operation, Hallam wasn't comfortable with the idea of his transplanted hand and failed to follow the prescribed post-operative drug and physiotherapy regime. His inaccurate expectations became a vivid example of the necessity of a ...
Xenozoonosis, also known as zoonosis or xenosis, is the transmission of infectious agents between species via xenograft. Animal to human infection is normally rare, but has occurred in the past. An example of such is the avian influenza, when an influenza A virus was passed from birds to humans.[33] Xenotransplantation may increase the chance of disease transmission for 3 reasons: (1) implantation breaches the physical barrier that normally helps to prevent disease transmission, (2) the recipient of the transplant will be severely immunosuppressed, and (3) human complement regulators (CD46, CD55, and CD59) expressed in transgenic pigs have been shown to serve as virus receptors, and may also help to protect viruses from attack by the complement system.[34] Examples of viruses carried by pigs include porcine herpesvirus, rotavirus, parvovirus, and circovirus. Porcine herpesviruses and rotaviruses can be eliminated from the donor pool by screening, however others (such as parvovirus and ...
Starzl was named one of the most important people of the Millennium, ranking No. 213, according to the authors of "1,000 Years, 1,000 People: Ranking the Men and Women Who Shaped the Millennium " (Kodansha America, 332 pp.)[1]. Starzl has also received honorary degrees from 26 universities in the United States and abroad, which include 12 in Science, 11 in Medicine, 2 in Humane Letters, and 1 in Law.[citation needed]. In 2006, at a celebration for his 80th birthday, the University of Pittsburgh renamed one of its newest medical research buildings the Thomas E. Starzl Biomedical Science Tower in recognition of his achievements and contributions to the field.[20] On October 15, 2007, the Western Pennsylvania American Liver Foundation and the City of Pittsburgh honored Starzl by dedicating Lothrop Street, near his office and the biomedical research tower bearing his name, as "Thomas E. Starzl Way".[21]. ...
One of the first mentions of the possibility of heart transplantation was by American medical researcher Simon Flexner, who declared in a reading of his paper on "Tendencies in Pathology" in the University of Chicago in 1907 that it would be possible in the then-future for diseased human organs substitution for healthy ones by surgery - including arteries, stomach, kidneys and heart.[4] Not having a human donor heart available, James D. Hardy of the University of Mississippi Medical Center transplanted the heart of a chimpanzee into the chest of a dying Boyd Rush in the early morning of Jan. 24, 1964. Hardy used a defibrillator to shock the heart to restart beating. This heart did beat in Rush's chest for 60 to 90 minutes (sources differ), and then Rush died without regaining consciousness.[5][6][7] Although Hardy was a respected surgeon who had performed the world's first human-to-human lung transplant a year earlier,[8][9] author Donald McRae states that Hardy could feel the "icy disdain" from ...
Heterologous polyclonal antibodies are obtained from the serum of animals (e.g., rabbit, horse), and injected with the patient's thymocytes or lymphocytes. The antilymphocyte (ALG) and antithymocyte antigens (ATG) are being used. They are part of the steroid-resistant acute rejection reaction and grave aplastic anemia treatment. However, they are added primarily to other immunosuppressives to diminish their dosage and toxicity. They also allow transition to cyclosporin therapy. Polyclonal antibodies inhibit T lymphocytes and cause their lysis, which is both complement-mediated cytolysis and cell-mediated opsonization followed by removal of reticuloendothelial cells from the circulation in the spleen and liver. In this way, polyclonal antibodies inhibit cell-mediated immune reactions, including graft rejection, delayed hypersensitivity (i.e., tuberculin skin reaction), and the graft-versus-host disease (GVHD), but influence thymus-dependent antibody production. As of March 2005, there are two ...
Endothelial keratoplasty (EK) has been introduced by Melles et al. in 1998. Today there are three forms of EK. Deep Lamellar Endothelial Keratoplasty (DLEK) in which the posterior part of the recipient cornea is replaced by donor tissue. Descemet's Stripping (Automated) Endothelial Keratoplasty (DSEK/DSAEK) in which the diseased Descemet's membrane is removed and replaced by a healthy donor posterior transplant. The transplant tissue can be prepared by a surgeon's hand or ordered already prepared for surgery. Ocular Systems was the first organization to deliver prepared grafts for surgery in 2005.[20] DSEK/DSAEK uses only a small incision that is either self-sealing or may be closed with a few sutures. The small incision offers several benefits over traditional methods of corneal transplant such as Penetrating Keratoplasty. Because the procedure is less invasive, DSAEK leaves the eye much stronger and less prone to injury than full-thickness transplants. New medical devices such as the EndoSaver ...
The patient, a 44-year-old male, had sustained the loss of most of his penis in an accident. The transplanted penis came from a ... The first successful penis transplant procedure was performed in September 2006, at a military hospital in Guangzhou. ... "Man rejects first penis transplant". The Guardian. London. Retrieved 22 May 2010 ...
In the classical sense, acute graft-versus-host-disease is characterized by selective damage to the liver, skin (rash), mucosa, and the gastrointestinal tract. Newer research indicates that other graft-versus-host-disease target organs include the immune system (the hematopoietic system, e.g., the bone marrow and the thymus) itself, and the lungs in the form of immune-mediated pneumonitis[1]. Biomarkers can be used to identify specific causes of GvHD, such as elafin in the skin.[2] Chronic graft-versus-host-disease also attacks the above organs, but over its long-term course can also cause damage to the connective tissue and exocrine glands[3] . Acute GvHD of the GI tract can result in severe intestinal inflammation, sloughing of the mucosal membrane, severe diarrhea, abdominal pain, nausea, and vomiting[4]. This is typically diagnosed via intestinal biopsy. Liver GvHD is measured by the bilirubin level in acute patients[5]. Skin GvHD results in a diffuse red maculopapular rash[6], sometimes in ...
Grafting refers to a surgical procedure to move tissue from one site to another on the body, or from another creature, without bringing its own blood supply with it. Instead, a new blood supply grows in after it is placed. A similar technique where tissue is transferred with the blood supply intact is called a flap. In some instances a graft can be an artificially manufactured device. Examples of this are a tube to carry blood flow across a defect or from an artery to a vein for use in hemodialysis. ...
The lung allocation score (LAS) is a numerical value used by the United Network for Organ Sharing (UNOS) to assign relative priority for distributing donated lungs for transplantation within the United States. The lung allocation score takes into account various measures of a patient's health in order to direct donated organs towards the patients who would best benefit from a lung transplant. The LAS system replaces the older method within the United States of allocating donated lungs strictly on a first-come, first-served basis, according to blood type compatibility and distance from the donor hospital. The older method is still used for patients under the age of 12. The LAS system is still being evaluated and revised.[1] The reason for this continuing analysis is the need to balance on one hand the desire to help those patients in direct need, versus the statistical likelihood of the patient to survive the procedure, as well as the post-operative risks of infection and transplant rejection.[2] ...
In the late nineteenth century and early twentieth century, trends in xenotransplantation included the work of Charles-Édouard Brown-Séquard.[10][11] In 1889, Brown-Séquard injected himself under the skin with extracts from ground-up dog and guinea pig testicles. These experiments failed to produce the desired results of increased hormonal effects to retard aging. Voronoff's experiments launched from this starting point. He believed glandular transplants would produce more sustained effects than mere injections. Voronoff's early experiments in this field included transplanting thyroid glands from chimpanzees to humans with thyroid deficiencies. He moved on to transplanting the testicles of executed criminals into millionaires, but, when demand outstripped supply, he turned to using monkey testicle tissue instead.[12] In 1917, Voronoff began being funded by Evelyn Bostwick, a wealthy American socialite and the daughter of Jabez Bostwick.[13] The money allowed him to begin transplantation ...
Allotransplant (allo- meaning "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. [1]The transplant is called an allograft, allogeneic transplant, or homograft. Most human tissue and organ transplants are allografts. It is contrasted with autotransplantation (from one part of the body to another in the same person), syngeneic transplantation (grafts transplanted between two genetically identical individuals of the same species) and xenotransplantation (from other species). Allografts can be referred to as "homostatic" if they are biologically inert when transplanted, such as bone and cartilage.[2] An immune response against an allograft or xenograft is termed rejection. An allogenic bone marrow transplant can result in an immune attack, called graft-versus-host disease. ...
Cancer of the cervix, vulva, vagina, penis, anus, mouth or throat[1][2]. ... They found high-risk HPV on 60% of these men, primarily the penis. "The specimens were obtained using a vigorous motion of the ... A Brazilian study used the readily available Qiagen/Digene test mentioned above (off label) to test men's penis, scrotum and ... penis, anus, mouth, or throat.[1][2] Nearly all cervical cancer is due to HPV with two types, HPV16 and HPV18, accounting for ...
1 on the CMJ charts,[2] and its accompanying first single, "Detachable Penis," became a modest hit, reaching No. 25 on the ... "Detachable Penis." According to Hall, the band realized that its hit song had drawn in many casual fans who didn't care about ... Billboard Modern Rock Tracks chart.[6] Atlantic released videos for "Detachable Penis" and the subsequent singles "(Why Are We ...
... small penis; accessory and wide-spaced nipples; broad or clubbed fingers; and sacral dimple. Those with deletions inclusive of ...
In the male cat, the genitalia includes the penis, which is covered with small spines.[35][36] ...
שמעקל): a little penis, often ascribed to a baby boy. Diminutive of שמאָק shmok, "penis." ... schmuck: a contemptible or foolish person; a jerk; literally means "penis" (from Yiddish שמאָק shmok 'penis') ... putz: unclean penis; stupid 'dirty' person, a jerk (from Yiddish פּאָץ pots, probably from Romanian puță, "dick") ... schlong (Yiddish שלאַנג): In vulgar usage, "penis." (from German Schlange, "snake"). *schlub (Yid. זשלאָב‎ zshlab): a clumsy, ...
Penis (male). *Scrotum (male). *Hair, Feather Aves, Scale Reptilia, Hair Mammalia, Fur ...
wána "penis" xwílena "bow" The final class IV consists of mostly abstract and deverbal nouns. All nouns in this class only are ...
... (Sanskrit: अपद्रव्य) is the generic name used in Kama Sutra for prostheses to increase the size of penis during ... If the penis has been subincised or meatotomized, the piercing is called a halfadravya. ... Because it passes through the most sensitive part of the penis, the procedure is among the most painful of male genital ... and other penis inserts of proto-Malay origins.[3] Indeed, traditional palang design is simply a pin used to accommodate a ...
A tanned bull's penis, a smoked horse's penis. There were runty, shriveled penises of reindeer, foxes, minks and rats. There ... He began collecting penises after a friend heard the story of the bull's penis in 1974 and gave him four new ones, three of ... There was the Big Penis - a 3-foot-long blue whale penis (which could have been an oar for a canoe).[5] ... They were hanging on the walls, stuffed in jars, displayed with curatorial love - dried penises, penises embalmed in ...
the penis, within the prepuce, also known as the "sheath".[4][5] Stallions have a vascular penis. When non-erect, it is quite ... by the increasing tumescence of the erectile vascular tissue in the corpus cavernosum penis.[6] When not erect, the penis is ... The retractor muscle contracts to retract the penis into the sheath and relaxes to allow the penis to extend from the sheath. ... "Penis and prepuce." Equine surgery 2 (2006): 540-557. *^ Hayes, Captain M. Horace; Knightbridge, Roy (2002). Veterinary Notes ...
Within the Felidae, male felids can urinate backwards by curving the tip of the glans penis backward.[136][137] Urine marking ... In placental mammals, urine is drained through the urinary meatus, a urethral opening in the male penis or female vulval ... See also: Human penis § Urination. Most males prefer to urinate standing while others prefer to urinate sitting or squatting. ... Occasionally, if a male's penis is damaged or removed, or a female's genitals/urinary tract is damaged, other urination ...
... testicles and penis bone of the dog, and snake bile.[120] Some TCM textbooks still recommend preparations containing animal ... The deer penis is believed to have therapeutic benefits according to traditional Chinese medicine.[132] It is typically very ... Medicinal tiger parts from poached animals include tiger penis, believed to improve virility, and tiger eyes.[133] The illegal ...
Jelqing - penis enlargement. *Non-surgical elongation of organs by prolonged stretching using weights or spacing devices. Some ... Headsplitting - splitting of both the underside and the top of the glans penis[citation needed] ... Body parts that are commonly removed by those practicing body nullification are: penis, testicles, clitoris, labia and nipples ... Genital bisection - splitting of both the underside and the top of the penis, including genital inversion[9] ...
... is the construction or reconstruction of a penis, or the artificial modification of the penis by surgery. The term ... "Shortened penis post penile prosthesis". MDLinx. Retrieved 16 February 2016.. *^ "A Retrospective Evaluation of the Safety and ... One-Stage Reconstruction of the Penis with Composite Iliac Crest and Lateral Groin Skin Flap by Sun, Guang-ci M.D.; Huang, Jin- ... Good sensation in the reconstructed penis can help reduce the risk of the implant eventually eroding through the skin.[4] ...
Heres our list of the best foods for your penis health. ... 8 Things Your Penis Is Telling You About Your Health. Believe ... 8 Things Your Penis Is Telling You About Your Health. Believe it or not, your favorite organ can be an informative fella. ... Hot sauce is one of the best condiments when it comes to your penis health. A 2015 study published in Physiology & Behavior ... Chocolate is one food that will satisfy your cravings and boost your penis health at the same time. Cacao increases levels of ...
A penis (plural penises or penes /-niːz/) is the primary sexual organ that male animals use to inseminate sexually receptive ... Body: the part of the penis extending from the roots. Glans: the free end of the penis. The internal structures of the penis ... of the penis. Pizzle, an archaic English word for penis, of Low German or Dutch origin, is now used to denote the penis of a ... egg-shaped glans penis. Near the top, the penis is haired, but the base is almost naked. In the baculum (penis bone), the shaft ...
A pseudo-penis is any structure found on an animal that, while superficially appearing to be a penis, is derived from a ... A notable example of a bird with a pseudo-penis is the red-billed buffalo weaver, which do not use their pseudo-penis for ... the fossas os clitoridis and pseudo-penis shrink as the juvenile female grows, unlike that of other pseudo-penis species.[3] ... This sections factual accuracy is disputed. Relevant discussion may be found on Talk:Pseudo-penis. Please help to ensure that ...
... penis pumps, penis extenders, jelqing and penis surgery. ... Do penis enlargement treatments work? Read the evidence on ... Penis surgery. Penis girth surgery. Some surgical techniques to increase penis girth involve injecting fat taken from another ... Penis pumps involve placing a tube over the penis and then pumping out the air to create a vacuum. The vacuum draws blood into ... Penis enlargement. The internet is awash with websites selling everything from pills to penis extenders that claim to increase ...
The penis is located above the scrotum. It is made of spongy tissue and blood vessels. ... The penis is the male organ used for urination and sexual intercourse. ... The penis is the male organ used for urination and sexual intercourse. The penis is located above the scrotum. It is made of ... Anomalies of the penis and urethra. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook ...
And theres a lot less difference in penis size between guys when they get an erection than when their penises are relaxed. ... such as whether the skin covering the penis is normal or if its OK for a guys penis to hang to the left or right (it is!). If ... Is My Penis Normal?. Just about every guy wonders how he measures up in the "down-there" department at one time or another. ... Growth in penis size is just one part of puberty, which also includes such changes as pubic hair development, testicular growth ...
Initial reports by Crawford [5] used an S-shaped incision on the dorsum of the penis to free the penis and fix the penis. The ... Figure 3: Trapped penis. This boy had a trapped penis, where a scar had formed over the penis. A conservative approach was ... The latter group is further divided as buried penis, webbed penis, and trapped penis. The primary aim of this paper is to ... this makes the penile skin look redundant and overhang the penis thus burying the penis. Webbed penis is the result of the ...
Penis pain is any pain or discomfort in the penis. ... How you treat penis pain at home depends on its cause. Talk to ... If penis pain is caused by a sexually transmitted disease, it is important for your sexual partner to also be treated. ... The physical exam will most likely include a detailed exam of the penis, testicles, scrotum, and groin. ... Is the pain in all of the penis or just one part of it? ... Cancer of the penis. *Erection that does not go away (priapism) ...
... fear that their penis is too small -- and seek unproven penis-lengthening treatments. But some men do suffer micropenis or ... Even normal-size men may suffer small-penis syndrome -- ... Abnormally small penis size is not.. Penis Size: Whats Normal ... Inconspicuous Penis: When Size Isnt the Only Issue. "Inconspicuous penis means a penis that is hard to see," Palmer says. ... "The webbed penis indicates the scrotum has connected to the underside of the penis so it pulls the penis inward," Palmer says ...
... local Roman Catholic priest Russell Calhoun reportedly lamented Tuesday the fact that God cursed him with an incredible penis. ... at least several of his churchs altar boys were blessed with the opportunity to gaze upon his sublime penis once a week. ... local Roman Catholic priest Russell Calhoun reportedly lamented Tuesday the fact that God cursed him with an incredible penis ...
Treatments and Tools for penis size. Find penis size information, treatments for penis size and penis size symptoms. ... MedHelps penis size Center for Information, Symptoms, Resources, ... My penis is very thin and in excited state it is about 4inch long.. is it normal.. ... Im 15 at the moment and I am going to be 16 in 6 months, Im 55 tall and my penis size is... ...
The glans of the penis is a sensitive, cone-shaped end to the shaft of the penis that covers the corpora cavernosa and bears ... Inside the glans penis, the corpus spongiosum is dilated and forms the navicular fossa. ...
Anatomy of the penis There are two types of erectile tissue in the penis, namely the corpora cavernosa and the corpus ... The cone-shaped glans penis at the distal end of the penis is an extension of the corpus spongiosum. The glans penis is covered ... glans penis and foreskin [from Latin, penis, or tail]. The shaft or body of the penis consists of two parallel cylindrical ... penises. Some species penises go further than this and perform additional functions to encourage reproduction. The penis and ...
There are many potential causes of white bumps on the penis, including whiteheads and Fordyce spots. Learn more about causes ... Other bumps on the penis. Bumps on or around the penis may be something other than whiteheads. In some cases, they could be a ... but they can also occur on the penis. When they occur on the penis, they are more common on the base or the shaft. ... White bumps on the penis may not always be whiteheads.. Whiteheads are a common form of acne. They are more common on areas of ...
Many sores on the penis occur due to sexually transmitted infections or chronic skin conditions. Learn about 12 possible causes ... The outlook for people with penis sores depends on the underlying cause. Typically, penis sores occur due to a STI or chronic ... Sores can appear on any part of the skin, including on the penis. Penis sores often result from a sexually transmitted ... Typically, the first symptom is a change in the skin of the penis, such as:. *a lump or small, crusty sore or ulcer that may ...
Symptoms and signs include irritation, a lump on the shaft of the penis, and bleeding. ... Amputation of the penis: Surgery to remove part or all of the penis. If part of the penis is removed, it is a partial penectomy ... Penis Picture. The penis is the male sex organ, reaching its full size during puberty. See a picture of the Penis and learn ... Penis cancer facts by John P. Cunha, DO, FACOEP. *Penis cancer is a disease in which malignant (cancer) cells form in the ...
A stiff penis in bed - Ein steifer Penis im Bett.jpg 1,920 × 1,080; 260 KB. ... A Penis Ring Placed on an Uncircumcised Human Penis.jpg 2,356 × 2,136; 1.21 MB. ... Animated Uncircumcised Penis Erection with Penis Ring.gif 640 × 480; 3.51 MB. ... Different views semi erect penis and erect penis.jpg 2,172 × 3,862; 674 KB. ...
Penis Bumps Tim761 Ok, so I had unprotected oral sex once. I gave and received it about 7 weeks ago. After doing this I had ... Penis Bumps. Ok, so I had unprotected oral sex once. I gave and received it about 7 weeks ago. After doing this I had these ... The day after I got tested though I notice these tiny little bumps on the back of my penis. So it been six weeks and these ... The day after I got tested though I notice these tiny little bumps on the back of my penis. So it been six weeks and these ...
Mostly used by men who have no penis. Most of them don't work. I should know..... ... I used a penis pump when my penis was 3, now my penis is 5. NOTE: NOT ALL PUMPS WORK! ... penis pump. A Vacuum tube used to lengthen the male tally-wacker. Mostly used by men who have no penis. Most of them don't ... penis pump. A device used to enlarge the penis. Pumping the handle will remove air to create a vacuum in the pump. This will ...
... furthermore when you forcibly cause there penis to come out they are small in size what is the normal penis size for this age ... i have two obese boys age 6 and 14 both have their penises that stay hidden to look at them the look as if they have a normal ... What your boys seem to be having is hidden or buried penis which is quite common in obesity due to the suprapubic fat covering ... the penis. If the boys are nor having any problem urinating, then there is nothing much to worry about. Losing weight or fat ...
My 3yo has what I am assuming is an infection in his penis. Its red and swollen, its hurting him, he has a fever, and pus ... He still has a little tenderness in the groin above his penis but his penis looks completely normal now and theres no ... He still has a little tenderness in the groin above his penis but his penis looks completely normal now and theres no ... He still has a little tenderness in the groin above his penis but his penis looks completely normal now and theres no ...
A ghost penis is an invisble penis you can't feel. Every female has one, you just can't see it. You can look behind ... Ghost Penis. A ghost penis is an invisble penis you can't feel. Every female has one, you just can't see it. You can ... Can I see your ghost penis? Why its invisble. But i can see whats behind it. (pick up) Ross has a ghost penis and i saw it ... Ghost Penis. A clumpy fold in your pants that looks like an erected penis.. Origin: Anthony Padilla from Smosh mentioned having ...
Your Penis in Peril. A dry patch of skin on this mans favorite body part became a health catastrophe. Heres how to spot a ... Hed have to inject an anesthetic at the base of the penis, but hed be using a very tiny needle. Im not sure why he thought ... Two weeks later, I was waiting for my penis biopsy. When my name was called, I was suddenly aware of all the people sitting ... Everyone knows a smart penis shrinks when its scared. I had a damn thimble on my hands. I wanted to shout all kinds of ...
AP) - A Kentucky man lost his bid Friday to force a doctor to pay damages for removing a cancer-riddled section of his penis ... AP) - A Kentucky man lost his bid Friday to force a doctor to pay damages for removing a cancer-riddled section of his penis ... Both sides agree that Seaton had squamous cell carcinoma, a type of skin cancer, in his penis. Patterson concluded that a tumor ... Patterson, a Kentucky-based urologist, maintains he found cancer in the mans penis during surgery and that it had to be ...
Just about every guy wonders about the size of his penis at one time or another. ... Penis size is determined by your genes , just like eye color or foot size. And theres a lot less difference in penis size ... For example, a guy might wonder if the skin covering the penis is normal or if its OK for a guys penis to hang to the left or ... There is a wide range of normal penis sizes. Although you may see guys with penises that are bigger or smaller than yours, it ...
Piercing your penis can be an excellent way to ramp up your sex life, feel good about yourself, and get a piercing that nobody ... Piercing your own penis can do irreversible damage to your penis including permanent impotence, severe nerve damages, necrosis ... v4-460px-Pierce-Your-Own-Penis-Step-1.jpg","bigUrl":"\/images\/thumb\/f\/fc\/Pierce-Your-Own-Penis-Step-1.jpg\/aid462361-v4- ... v4-460px-Pierce-Your-Own-Penis-Step-2.jpg","bigUrl":"\/images\/thumb\/f\/f5\/Pierce-Your-Own-Penis-Step-2.jpg\/aid462361-v4- ...
DOCTORS in the US have performed the worlds first complete penis and scrotum transplant on a former soldier who had his ... Two other successful penis transplants have been performed in the past - one in South Africa in 2014 and anotherat the ... DOCTORS in the US have performed the worlds first complete penis and scrotum transplant on a former soldier who had his ... I feel whole again: US doctors perform unprecedented complete penis transplant. A US soldier who "struggled with even viewing ...
More:bull penisEatingKoreanNORTHERN CHINESEnsfwOFFALOrgan Meat SocietyOrgan Recitalpenis ... Therefore, bull penis (which is much more slender than youd expect - how does he pleasure the cow?) is translucent and chewy. ... Here, we must just be content with the arcane thrill of eating - animal penis. And I dont blame you for being a bit squeamish. ... Some bull penises have a right angle in them. Mosby: Diseases and Disorders of Cattle, 1997 ...
Can a boys penis go on a girl? Yes a penis can go on a girl, with her permission. But know the consequences. If the penis gets ... Can a boys penis fall off? If a boy were to cut off circulation to his penis with a string, rope, rubber band, etc. it would ... Why does a boys penis stick up? I asume you mean when they get "hard" or aroused? A boy or mans penis "sticks up" because ... Are girls attracted to a boys penis? Most heterosexual girls are attracted to a boys penis, as well as most of the defining ...
Heres what you need to know about penis size, and what to do if youre afraid your penis is smaller than ... Just about every man-regardless of the actual size of his penis-worries about being too small. ... There are few topics that can evoke such widespread and intense anxiety as penis size. ... Try a penis extender or sleeve. If you really want the experience of having a longer and girthier penis, you can buy penis ...
  • Pearly penile papules are small, fleshy bumps that usually develop in rows around the head of the penis. (medicalnewstoday.com)
  • Tyson glands are small sebaceous glands that can form on either side of the frenulum, which is the elastic tissue that connects the foreskin to the head of the penis. (medicalnewstoday.com)
  • Genital warts appear as small, flesh-white bumps that grow on the shaft or head of the penis or under the foreskin. (medicalnewstoday.com)
  • The glans (head of the penis) is covered with loose skin called the foreskin. (medicinenet.com)
  • The early forms of penile cancer typically have symptoms that include a rash or infection on either the head of the penis (glans) or the foreskin (prepuce). (healthline.com)
  • These are small flesh-coloured lumps normally found on the head of the penis. (www.nhs.uk)
  • Genital warts are small fleshy growths or bumps that can appear on the shaft, and sometimes head, of the penis or under the foreskin. (www.nhs.uk)
  • Penile cancer is a rare type of cancer that can cause a sore or lump on the penis, most commonly on the head of the penis. (www.nhs.uk)
  • And my other concern is that my head of the penis is a little white. (scarleteen.com)
  • It can take anywhere from 2 to 6 years for the foreskin to separate from the glans (head of the penis). (wikihow.com)
  • Penile pain can affect the base, shaft, or head of the penis. (healthline.com)
  • Balanitis is an infection of the foreskin and the head of the penis. (healthline.com)
  • Phimosis happens in uncircumcised males when the foreskin of the penis is too tight and it can't be pulled away from the head of the penis. (healthline.com)
  • A related condition called paraphimosis happens if your foreskin pulls back from the head of the penis, but then can't return to its original position covering the penis. (healthline.com)
  • About 45% of his brethren want a bigger penis. (webmd.com)
  • Having a bigger penis doesn't equate feeling more pleasure during sex. (lifehacker.com)
  • Psychological Benefits Of Having A Bigger Penis. (scoop.it)
  • Weight loss = bigger penis? (scarleteen.com)
  • It is our human nature that wants us understand that have got a bigger penis than other men out certainly there. (dailystrength.org)
  • the penis, which is typically coiled up in flaccid state, can reach about the same length as the animal himself when fully erect, but is more commonly about half the bird's length. (wikipedia.org)
  • In many mammals, the size of a flaccid penis is smaller than its erect size. (wikipedia.org)
  • [12] This organ, called a pendulous clitoris because of the way it dangles externally, is actually larger than the male flaccid penis. (wikipedia.org)
  • This technique involves placing a weight or a small extending frame, sometimes called a traction device, on the flaccid penis to stretch it. (www.nhs.uk)
  • Jelqing is an exercise involving repeatedly pulling the flaccid penis using the thumb and index finger, with the aim of increasing erection size. (www.nhs.uk)
  • Just like using lotions, this technique can help some men better appreciate the considerable difference in size between a flaccid penis and an erect one, which helps them become more comfortable with their body," says Professor Wylie. (www.nhs.uk)
  • To learn your SPL, measure the penis while it's flaccid. (webmd.com)
  • Generally, most foreskins are long enough to cover the glans when the penis is flaccid. (wikimedia.org)
  • wondering if my penis would grow on flaccid it measures around 3 and a half sometimes 4 inchs but seems to only grow an inch on erect but. (medhelp.org)
  • my penis size is 3 inch flaccid and 5.5 erect. (medhelp.org)
  • In its relaxed (flaccid, i.e. soft/limp) state, the shaft of the penis has the feel of a dense sponge encased in very smooth eyelid-type skin. (wikipedia.org)
  • Neither age nor size of the flaccid penis accurately predicts erectile length. (wikipedia.org)
  • Body of the penis (corpus): It has two surfaces: dorsal (posterosuperior in the erect penis), and ventral or urethral (facing downwards and backwards in the flaccid penis). (wikipedia.org)
  • Another example is that circumcised penises can look smaller while flaccid due to the lack of a foreskin. (redorbit.com)
  • However, these measurements were taken on flaccid penises, which studies have shown are more difficult to measure accurately. (redorbit.com)
  • Another aspect to remember is that flaccid penis size is not necessarily an accurate indicator of how big it will be when erect. (redorbit.com)
  • There is a much closer correlation between the size of your penis when it is erect and the size when it is flaccid and stretched out - that is, when it is pulled lengthwise to elongate the muscles and skin. (redorbit.com)
  • Suspensory ligament release increases flaccid penis length, but does not increase the length of an erect penis and can create problems with sexual function. (wikipedia.org)
  • And there's a lot less difference in penis size between guys when they get an erection than when their penises are relaxed. (kidshealth.org)
  • The longer a man's SPL, the longer his erect penis length, according to studies done on brave young men who volunteered to have erection-stimulating penis injections. (webmd.com)
  • A penis' erection helps to deliver semen deeper into the female reproductive tract during sexual intercourse. (innerbody.com)
  • Treatment for priapism is a medical emergency, because a prolonged erection can scar the penis and result in a long term complication of erectile dysfunction if if not treated. (medicinenet.com)
  • The hardened plaque reduces flexibility, causing pain and forcing the penis to bend or arc during erection. (medicinenet.com)
  • The skin of the penis is loose and elastic to accommodate changes in penis size during an erection. (clevelandclinic.org)
  • Bending or arcing of the penis during an erection. (clevelandclinic.org)
  • Any type of pain in the penis is a cause for concern, particularly if it occurs during an erection, prevents urination, or occurs along with discharge, sores, redness, or swelling. (healthline.com)
  • Because the scar tissue forms next to the tissue that becomes hard during an erection, you may notice that your penis bends when it's erect. (healthline.com)
  • Draining the blood from the penis with a needle helps reduces an erection if you have priapism. (healthline.com)
  • [1] [2] An erection is the stiffening and rising of the penis, which occurs during sexual arousal , though it can also happen in non-sexual situations. (wikipedia.org)
  • Some quack products may improve penis erection, mistaken by consumers for penis enlargement. (wikipedia.org)
  • Commonly called a "penis pump", a vacuum erection device, or VED, creates negative pressure that expands and thereby draws blood into the penis. (wikipedia.org)
  • The scientists say that the stimulant triggers a series of reactions in the body that ultimately increase blood flow to the penis. (bestlifeonline.com)
  • Medications that help shrink blood vessels, which decreases blood flow to the penis, also may be used. (medicinenet.com)
  • ProSolution gel combines various known ingredients and aphrodisiacs to create a natural formula that results in increased blood flow to the penis. (selfgrowth.com)
  • The urethra is on the ventral side of the body of the penis. (wikipedia.org)
  • The shaft or body of the penis consists of two parallel cylindrical bodies, the corpora cavernosa , and beneath them, surrounding the urethra, the corpus spongiosum . (everything2.com)
  • Once the cancer begins to spread to the body of the penis, the area known as the corpora cavernosa, treatment becomes serious. (healthline.com)
  • Roughly cylindrical in shape, the body of the penis is the largest region. (innerbody.com)
  • The body of the penis is cylindrical in shape and consists of three internal chambers. (clevelandclinic.org)
  • But according to the evolutionary psychologist Gordon Gallup, the human penis is actually an impressive "tool" in the truest sense of the word, one manufactured by nature over hundreds of thousands of years of human evolution. (huffingtonpost.com)
  • Gallup's approach to studying the design of the human penis is a perfect example of reverse engineering as the term is used in the field of evolutionary psychology. (huffingtonpost.com)
  • But in the case of the human penis, all signs point to a genuine adaptive reason that it has come to look the way it does. (huffingtonpost.com)
  • First, despite variation in size between individuals, the human penis is especially large compared with that of other primates. (huffingtonpost.com)
  • It turns out that one of the most significant features of the human penis isn't so much the glans per se as the coronal ridge it forms underneath. (huffingtonpost.com)
  • The human penis is an external male intromittent organ that additionally serves as the urinal duct . (wikipedia.org)
  • While results vary across studies, the consensus is that the average erect human penis is approximately 12.9-15 cm (5.1-5.9 in) in length with 95% of adult males falling within the interval 10.7-19.1 cm (4.2-7.5 in). (wikipedia.org)
  • It is the sensitive bulbous structure at the end of the human penis , and is anatomically homologous to the clitoral glans of the human female. (wikipedia.org)
  • In comparison, the human penis is larger than that of any other primate, both in proportion to body size and in absolute terms. (wikipedia.org)
  • Penis enlargement, or male enhancement, is any technique aimed to increase the size of a human penis. (wikipedia.org)
  • The penis is located above the scrotum . (medlineplus.gov)
  • Penis and scrotum. (medlineplus.gov)
  • The superficial Scarpa's fascia covers the anterior abdominal wall and is continuous with the superficial fascia of the penis and scrotum to the external genitalia called the dartos fascia. (hindawi.com)
  • The physical exam will most likely include a detailed exam of the penis, testicles, scrotum, and groin. (medlineplus.gov)
  • Don't just measure from where the penis separates from the scrotum, or you'll lose precious centimeters. (webmd.com)
  • i have two obese boys age 6 and 14 both have their penises that stay 'hidden' to look at them the look as if they have a normal scrotum without an actual penis. (medhelp.org)
  • DOCTORS in the US have performed the world's first complete penis and scrotum transplant on a former soldier who had his genitals blown off after stepping on a hidden bomb while on tour in the Middle East. (news.com.au)
  • The young army veteran received an entire penis, scrotum (without testicles), and partial abdominal wall from a deceased donor. (news.com.au)
  • The penis is located in the pubic region superior to the scrotum and inferior to the umbilicus along the body's midline. (innerbody.com)
  • The man, whose name was changed in the original Russian news article to protect his privacy, had a defect from birth - his penis was crooked, two-and-a-half inches long and lacked a scrotum. (laweekly.com)
  • To be missing the penis and parts of the scrotum is devastating," Dr. Redett said. (nytimes.com)
  • The internal structures of the penis consist mainly of cavernous, erectile tissue, which is a collection of blood sinusoids separated by sheets of connective tissue (trabeculae). (wikipedia.org)
  • The idea is that the pulling exercises will increase the blood capacity of the penis' erectile tissue, allegedly resulting in increased length and girth of the penis. (www.nhs.uk)
  • There are two types of erectile tissue in the penis, namely the corpora cavernosa and the corpus spongiosum . (everything2.com)
  • The two columns of erectile tissue that form most of the penis. (medicinenet.com)
  • Corpus spongiosum: The single column of erectile tissue that forms a small portion of the penis. (medicinenet.com)
  • It took a team of nine plastic surgeons and two urology surgeons to work to attach the urethra, erectile tissue, arteries, veins, nerves and skin of the penis and abdominal wall to its new owner. (news.com.au)
  • Erectile tissue inside the penis allows the penis to increase in size and become rigid during sexual stimulation. (innerbody.com)
  • These regions of erectile tissue fill with blood to harden and enlarge the penis during times of sexual excitement. (innerbody.com)
  • The plaque may develop on the upper (more common) or lower side of the penis, in the layers that contain erectile tissue. (medicinenet.com)
  • The plaque may develop on the upper (more common) or lower side of the penis, in the elastic layers that surround erectile tissue. (clevelandclinic.org)
  • Inside the glans penis, the corpus spongiosum is dilated and forms the navicular fossa. (innerbody.com)
  • The cone-shaped glans penis at the distal end of the penis is an extension of the corpus spongiosum . (everything2.com)
  • The urethra traverses the corpus spongiosum, and its opening, the meatus ( / m iː ˈ eɪ t ə s / ), lies on the tip of the glans penis. (wikipedia.org)
  • The enlarged and bulbous-shaped end of the corpus spongiosum forms the glans penis , which supports the foreskin , or prepuce, a loose fold of skin that in adults can retract to expose the glans. (wikipedia.org)
  • The glans penis is the expanded cap of the corpus spongiosum . (wikipedia.org)
  • Penile cancer is usually found on the glans or foreskin of the penis but can also occur on the shaft of the penis. (medicinenet.com)
  • Having phimosis (a condition in which the foreskin of the penis cannot be pulled back over the glans). (medicinenet.com)
  • PeIN on the glans (head) or foreskin of the penis is also called erythroplasia of Queyrat. (cancer.ca)
  • I snapped to attention when I examined the separate menu of tableside barbecue selections, since it offered lots of organ meats, including mutton testicles and bull penis. (villagevoice.com)
  • She pulled an atlas of anatomy off the shelf and explained to me what the differences are between the penis and testicles, vagina and clitoris. (zeit.de)
  • No tight underwear does not cause any problems with your penis, testicles or your sperm. (yahoo.com)
  • Some lost all or part of their penises or testicles - what doctors call genitourinary injuries . (nytimes.com)
  • Men who have lost testicles completely may still be able to have penis transplants, but they will not be able to have biological children. (nytimes.com)
  • Another method, still in its experimental stage, involves pulling back the skin of the penis to wrap a tube-like biodegradable frame filled with tissue cells around the shaft. (www.nhs.uk)
  • The shaft of the penis surrounds the urethra and is connected to the pubic bone. (medlineplus.gov)
  • According to this classification, the reason for inconspicuous penis could be a short penile shaft, that is, micropenis, or more commonly due to abnormalities of the investing structures. (hindawi.com)
  • The shaft of the penis itself is suspended by suspensory ligaments that extend from the inferior aspect of the pubic arch to the base of the penis in the dorsal aspect. (hindawi.com)
  • An excess of suprapubic fat that normally stops at the base of the penis, could extend and stretch the skin of the penis thus obliterating the penopubic junction making the penis look shorter by hiding part of the shaft of the penis. (hindawi.com)
  • The glans of the penis is a sensitive, cone-shaped end to the shaft of the penis that covers the corpora cavernosa and bears the urethral opening. (innerbody.com)
  • When they occur on the penis, they are more common on the base or the shaft. (medicalnewstoday.com)
  • They are common on the lips and inside the cheeks, but they may also form around the head or shaft of the penis. (medicalnewstoday.com)
  • Fordyce spots are small yellowish or white spots on the head or shaft of the penis. (www.nhs.uk)
  • This is a hard swelling that suddenly appears on the shaft of the penis after sex or masturbation. (www.nhs.uk)
  • Peyronie's disease is an uncommon condition that causes a thickened area or hard lump (plaque) in the shaft of the penis. (www.nhs.uk)
  • About a week ago, it started burning when I urinate, also began itching INSIDE the penis all along the shaft and having a. (askmehelpdesk.com)
  • Peyronie's disease starts when an inflammation causes a thin sheet of scar tissue, called plaque, to form along the upper or lower ridges of the shaft of the penis. (healthline.com)
  • For men this problem can be coped with by employing an indwelling catheter or more commonly in ambulatory patients by use of an external catheter which is adhered to the shaft of the penis by a double sided adhesive strip. (google.es)
  • and the epithelium of the penis including the shaft skin and the foreskin (prepuce) covering the glans penis . (wikipedia.org)
  • In its fully erect state, the shaft of the penis is rigid, with the skin tightly stretched. (wikipedia.org)
  • Epithelium of the penis consists of the shaft skin , the foreskin , and the preputial mucosa on the inside of the foreskin and covering the glans penis . (wikipedia.org)
  • On some penises it is much wider in circumference than the shaft, giving the penis a mushroom-like appearance, and on others it is narrower and more akin to a probe in shape. (wikipedia.org)
  • [20] The glans of a fossa's penis extends about halfway down the shaft and is spiny except at the tip. (wikipedia.org)
  • PeIN on the shaft of the penis is also called Bowen's disease. (cancer.ca)
  • Performed on the halfway tumescent penis, jelqing is a manual manipulation of simultaneous squeezing and stroking the shaft from base to corona. (wikipedia.org)
  • In most species of animals in which there is an organ that might reasonably be described as a penis, it has no major function other than intromission, or at least conveying the sperm to the female, but in the placental mammals the penis bears the distal part of the urethra, which discharges both urine during urination and semen during copulation. (wikipedia.org)
  • Anomalies of the penis and urethra. (medlineplus.gov)
  • The penis contains the external opening of the urethra, which is used for urination and to deliver semen into the vagina of a female sexual partner. (innerbody.com)
  • Semen travels through the urethra to the tip of the penis where it is ejaculated out of the body. (innerbody.com)
  • As an excretory organ, the penis delivers urine out of the body through the urethra. (innerbody.com)
  • The opening of the urethra, the tube that transports semen and urine out of the body, is located at the tip of the glans penis. (clevelandclinic.org)
  • The human male urethra passes through the prostate gland , where it is joined by the ejaculatory duct , and then through the penis. (wikipedia.org)
  • the skin around the penis and the urethra come from the same embryonic tissue from which develops the labia minora in females. (wikipedia.org)
  • The meatus (opening) of the urethra is located at the tip of the glans penis. (wikipedia.org)
  • You might think that as long a man's penis works, he would have no problem with it. (webmd.com)
  • Penis size is a key element of a man's self-image. (webmd.com)
  • Patterson, a Kentucky-based urologist, maintains he found cancer in the man's penis during surgery and that it had to be removed. (yahoo.com)
  • Disorders of the penis and testes can affect a man's sexual functioning and fertility . (medicinenet.com)
  • In fact, there are some ladies who claimed who could tell a man's bank account, sex life, and penis size just by looking at his face. (scoop.it)
  • First, John the Conqueor root, as far as i know, does not increase the ultimate erect size of a man's penis. (luckymojo.com)
  • Medically approved VEDs, which treat erectile dysfunction, limit maximum pressure, whereas the pumps commonly bought by consumers seeking penis enlargement can reach dangerous pressure, damaging penis tissue. (wikipedia.org)
  • Using a pump for a few minutes a day won't do anything to increase penis size. (www.nhs.uk)
  • But there's no scientific evidence to suggest jelqing can increase penis size. (www.nhs.uk)
  • Experts seem to agree that the ONLY thing that can increase penis size is time, which would run contrary to this story. (scarleteen.com)
  • Just as many men are below average penis size as above it. (webmd.com)
  • It's difficult to determine the true average penis size for a variety of reasons, including reporting bias and cross-cultural differences, but a recent comprehensive review found that the average is a little over 5 inches when erect. (lifehacker.com)
  • It's a question that nearly every man will ask at some point in his life: what it the average penis size, and how do I measure up? (redorbit.com)
  • Professor Wylie assesses the evidence, effectiveness and safety of different types of penis enlargement products and treatments on the market. (www.nhs.uk)
  • ProSolution Gel is one of the common names you will encounter when looking for the best penis enlargement cream in the market . (selfgrowth.com)
  • Unlike most scams that claim to offer the best penis enlargement cream , ProSolution does offer a detailed webpage and contact information for any inquiries. (selfgrowth.com)
  • One of the reasons that put ProSolution gel among the best penis enlargement cream products is its safety and use of natural ingredients. (selfgrowth.com)
  • Whether it represents the ultimate solution to enlargement in penis size is no longer debatable. (bartleby.com)
  • Penis stretching, eyebrow botox, wrist enlargement, "neck training," nostril shrinking and 3D-printed skull implants are among the desired procedures and "coping strategies" discussed at length on these sites. (huffingtonpost.com)
  • Subject: Re: spell for breast and penis enlargement? (luckymojo.com)
  • The maker of ExtenZe, known for its late-night penis-enlargement commercials, has agreed to pay $1.75 million in penalties to settle an unfair business settlement. (ibtimes.com)
  • California-based Biotab Neutraceuticals was accused by the Orange County district attorney's office of making unsubstantiated advertising claims for some of its supplements, most notably its penis-enlargement campaign. (ibtimes.com)
  • Noogleberry's eBay shop for all your penis enlargement needs. (ebay.co.uk)
  • There are several surgical penis enlargement treatments, most of which carry a risk of significant complications. (wikipedia.org)
  • Surgical penis enlargement methods include penile augmentation and suspensory ligament release. (wikipedia.org)
  • Complications from penis enlargement procedures include scarring that may lead, ultimately, to penis shrinkage or erectile dysfunction. (wikipedia.org)
  • A 2019 study in Sexual Medicine Reviews found that surgical methods of penis enlargement are typically ineffective and can be damaging to both physical and mental health. (wikipedia.org)
  • Penis-enlargement pills, patches, and ointments are sold online. (wikipedia.org)
  • Although vacuum therapy can treat erectile dysfunction sufficiently to prevent penis deterioration and shrinkage, clinical trials have not found it effective for penis enlargement. (wikipedia.org)
  • There's a fairly wide range of normal penis sizes - just as there is for every other body part. (kidshealth.org)
  • There is a wide range of normal penis sizes. (kidshealth.org)
  • Tests that examine the penis are used to detect (find) and diagnose penile cancer. (medicinenet.com)
  • In fact, treating penile cancer that has spread throughout the penis, may, for some men, be worse than the disease itself. (healthline.com)
  • Penile cancer, also identified as penis cancer, is a rare form of cancer to be found occurring in the penis. (medic8.com)
  • Disorders which can affect the penis include priapism, balanitis, penile cancer, erectile dysfunction and ejaculatory disorders. (clevelandclinic.org)
  • Penile cancer is another cause of pain in the penis, although it's uncommon. (healthline.com)
  • Although there is some evidence that circumcision reduces the risk of penile cancer, there is not enough evidence to recommend circumcision as a way of preventing cancer of the penis. (cancer.ca)
  • Growth in penis size is just one part of puberty, which also includes such changes as pubic hair development, testicular growth, muscle development, and a growth spurt. (kidshealth.org)
  • Press the ruler tight against the pubic bone at the base of the penis. (webmd.com)
  • Measure from the pubic bone to the tip of the stretched penis. (webmd.com)
  • The outside of the penis is covered with skin that is continuous with the skin of the surrounding pubic region. (innerbody.com)
  • Place the end of your ruler or measure on the top of your penis (as in the opposite side to your balls), where it connects to your pubic bone. (redorbit.com)
  • Inflammation of the glans penis is known as balanitis , and, occurs in 3-11% of males (up to 35% of diabetic males). (wikipedia.org)
  • Balanitis xerotica obliterans (BXO) is an inflammatory condition of the skin that affects the foreskin and the glans of the penis. (cancer.ca)
  • They can affect the penis and general groin area, in which case it's considered an STI. (www.nhs.uk)
  • What disorders affect the penis? (medicinenet.com)
  • There are several disorders that can affect the penis. (clevelandclinic.org)
  • As with any other bodily attribute, the length and girth of the penis can be highly variable between mammals of different species. (wikipedia.org)
  • The internet is awash with websites selling everything from pills to penis extenders that claim to increase the length and girth of your manhood. (www.nhs.uk)
  • If you are looking for the size of your penis in order to purchase condoms, measure the length and girth of your penis when it is erect. (redorbit.com)
  • The glans penis is covered by a loose fold of skin called the prepuce or foreskin . (everything2.com)
  • [18] [19] In cats, the glans penis is covered with spines, but in dogs, the glans is smooth. (wikipedia.org)
  • furthermore when you forcibly cause there penis to come out they are small in size what is the normal penis size for this age group? (medhelp.org)
  • Sure, there are people who would prefer a larger-than-normal penis. (lifehacker.com)
  • What is the Normal Penis Size for a Teen? (redorbit.com)
  • So then, what is the normal penis size for a teen? (redorbit.com)
  • In this case, the male has a vagina-like structure while the female has a pseudo-penis. (wikipedia.org)
  • Some may be confused, wondering why the individuals with a vagina-like structure are considered male while the ones with the pseudo-penis are considered female. (wikipedia.org)
  • insult) i have a ghost penis and a vagina! (urbandictionary.com)
  • The rectum isn't capable of stretching in the same way a vagina is, so a smaller penis feels better than a larger one. (lifehacker.com)
  • As a reproductive organ, the penis becomes erect during sexual intercourse in order to deliver semen more effectively into the vagina. (innerbody.com)
  • In an article published in the journal Evolutionary Psychology, Gallup and Rebecca Burch argue that "a longer penis would not only have been an advantage for leaving semen in a less accessible part of the vagina, but by filling and expanding the vagina it also would aid and abet the displacement of semen left by other males as a means of maximizing the likelihood of paternity. (huffingtonpost.com)
  • Will your penis hurt inside a vagina? (answers.com)
  • They can protect the penis from HIV -infected vaginal fluids and blood in the mouth , vagina, or rectum. (thebody.com)
  • But more commonly, this inconspicuous appearance is secondary to other causes ranging from congenital conditions such as penoscrotal webbing or megaprepuce, developmental conditions like prepubic adiposity that overhang the penis, and iatrogenic causes like trapped penis after adhesions secondary to circumcision. (hindawi.com)
  • A circumcision is an operation in which the doctor removes part or all of the foreskin from the penis. (medicinenet.com)
  • An uncircumcised penis still has its foreskin because it was not removed during a circumcision surgery. (wikimedia.org)
  • AP) - A Kentucky man lost his bid Friday to force a doctor to pay damages for removing a cancer-riddled section of his penis during what was scheduled to be a simple circumcision. (yahoo.com)
  • A unanimous jury ruled in favor of the Kentucky doctor who amputated a portion of Phillip Seaton's penis during an October 2007 circumcision to treat inflammation. (go.com)
  • Circumcision, Mill explains, does involve lopping off the foreskin and, often, quite a bit of the frenulum-sensitive parts of the penis involved in feeling pleasure. (menshealth.com)
  • LOUISVILLE, Ky (Reuters) - A Kentucky doctor acted properly when he amputated part of a truck driver's penis after finding cancer during what was expected to have been a routine circumcision surgery in 2007, a jury found on Wednesday. (reuters.com)
  • The effects of circumcision on the penis microbiome. (nih.gov)
  • But the South African recipient, a young man whose penis had been amputated because of a botched circumcision , recently became a father, said Dr. Gerald Brandacher, the scientific director of the reconstructive transplantation program at Johns Hopkins. (nytimes.com)
  • A penis (plural penises or penes /-niːz/) is the primary sexual organ that male animals use to inseminate sexually receptive mates (usually females and hermaphrodites respectively) during copulation. (wikipedia.org)
  • The penis is the male organ used for urination and sexual intercourse. (medlineplus.gov)
  • NEW MILTON, WV-Asking whether possession of an exceptional sexual organ he was forbidden to use was perhaps a test from the Lord, local Roman Catholic priest Russell Calhoun reportedly lamented Tuesday the fact that God cursed him with an incredible penis. (theonion.com)
  • The penis is a rod-shaped male reproductive organ that passes sperm and urine from the body. (medicinenet.com)
  • The penis is the male external excretory and sex organ. (innerbody.com)
  • The penis is an organ made of several distinct tissue layers. (innerbody.com)
  • The penis functions as both a reproductive organ and an excretory organ. (innerbody.com)
  • If you were to examine the penis objectively-please don't do this in a public place or without the other person's permission-and compare the shape of this organ with the design of the same organ in other species, you'd notice the following uniquely human characteristics. (huffingtonpost.com)
  • We often get away with such self-torture because the penis is a resilient organ. (menshealth.com)
  • The penis is an external organ in the male reproductive system. (clevelandclinic.org)
  • However, unlike the penis, the breast is an organ designed to change sizes over the course of a woman's life. (luckymojo.com)
  • When it mates, it extrudes around a centimetre of penis, but the full organ is three centimetres long. (nationalgeographic.com)
  • Sekizawa thinks that it's too difficult for the animal to retract a used penis, and is forced to discard its one-shot organ. (nationalgeographic.com)
  • Not all animal species have a male penis, but because the evolution of body parts usually works through slow modification of existing structures, there would need to be a good reason for a female to develop a penetrating organ, says entomologist Kazunori Yoshizawa of Hokkaido University in Japan, a co-author of the study. (scientificamerican.com)
  • There are severe reproductive costs as a result of the female spotted hyena's pseudo-penis. (wikipedia.org)
  • Men worried about their penis size usually have some other excuse for seeing a doctor, says Bruce R. Gilbert, MD, PhD, director of reproductive and sexual medicine at the Smith Institute for Urology in Lake Success, N.Y. (webmd.com)
  • The penis is one of the external structures of the male reproductive system . (clevelandclinic.org)
  • Semen, which contains sperm (the male reproductive cells), is expelled through the end of the penis when the man reaches sexual climax (orgasm). (clevelandclinic.org)
  • The latter is very rarely done - though in 2015, a Florida urologist reported that he had successfully reduced the penile size of a young man whose penis was the size and shape of an American football (as a result of complications of sickle cell anaemia). (netdoctor.co.uk)
  • Chemical pollutants may be reducing the density of the bears' penis bones, putting them at risk of breaking this most intimate part of their anatomy. (newscientist.com)
  • You may want to check out our article Innies & Outies: The Penis, Testes, & More for more information about male sexual anatomy. (scarleteen.com)
  • The male anatomy showing the location of the glans penis. (wikipedia.org)
  • This might be a combination unique to Neotrogla , he says: Although other animals have swapped sex roles where the female is the promiscuous aggressor (the scorpion fly, for example), and others have swapped anatomy where the female penetrates the male (seahorses, for example), none appears to have developed both reversed sex roles and a female penis with grappling hooks. (scientificamerican.com)
  • the glans penis contains a predominance of free nerve endings, numerous genital end bulbs and rarely Pacinian and Ruffinian corpuscles. (wikipedia.org)
  • The mammalian pseudo-penis appears to be simply for display, though the spotted hyena is an exception: the female spotted hyena additionally uses her pseudo-penis for urination, sexual intercourse, and to give birth. (wikipedia.org)
  • Many sensory receptors in the penis' skin allow it to receive sensory stimulation during sexual intercourse. (innerbody.com)
  • But because complications can occur, and because many of the problems associated with Peyronie's disease (for example, shortening of the penis) are not corrected by surgery, most doctors prefer to perform surgery only on men with curvatures so severe that sexual intercourse is impossible. (medicinenet.com)
  • As the penis fills with blood, it becomes rigid and erect, which allows for penetration during sexual intercourse. (clevelandclinic.org)
  • Male and female emus are similar in appearance, although the male's penis can become visible when it defecates. (wikipedia.org)
  • The tip of the female's penis fits neatly into the male's genitalia to allow her to receive a large, teardrop-shaped sperm capsule over their 40-70 hours of copulation. (scientificamerican.com)
  • Obviously I can't diagnose your penis accurately without seeing it, but the most likely cause is a mild case of thrush (a common fungus infection). (netdoctor.co.uk)
  • Penis sores often result from a sexually transmitted infection or a skin condition. (medicalnewstoday.com)
  • In the early stages of infection, syphilis usually causes a hard, painless, red sore on the penis. (medicalnewstoday.com)
  • The infection causes small, red, raised sores to form on the penis. (medicalnewstoday.com)
  • Causes and risk factors for developing penis cancer include human papillomavirus ( HPV ) infection, not being circumcised, being age 60 or older, phimosis , poor hygiene , many sexual partners, AIDS , UV treatment for psoriasis , and tobacco use. (medicinenet.com)
  • My 3yo has what I am assuming is an infection in his penis. (mothering.com)
  • They're usually diabetics who have poor overall health and are prone to infection, and they think it is just another infection on the penis. (healthline.com)
  • If you have any ulcer or lesion on the penis that does not heal with the traditional treatment for possible infection, then you should immediately seek referral to a dermatologist or a urologist," said Gill. (healthline.com)
  • Phillip Seaton, 64, had sought $16 million in damages against Dr. John Patterson for performing the partial amputation after he discovered a cancerous tumor on Seaton's penis during the surgery, which had been expected to uncover a fungal infection. (reuters.com)
  • I have red, chapped-looking skin under my foreskin on the underside of my penis. (netdoctor.co.uk)
  • On the underside of the penis, there is that 'line' that runs up the center. (mothering.com)
  • My ped is intact-friendly and has never examined his penis, so no one other than me has ever really seen the underside. (mothering.com)
  • I recently noticed a small lump on the underside of my penis. (medhelp.org)
  • The area on the underside of the penis, where the foreskin is attached, is called the frenum , or frenulum. (wikipedia.org)
  • The perineal raphe is the noticeable line along the underside of the penis. (wikipedia.org)
  • in some instances, removal of the penis may be necessary. (wikipedia.org)
  • In most cases, treatment involves draining the blood using a needle placed in the side of the penis. (medicinenet.com)
  • Draining the blood using a needle placed in the side of the penis. (clevelandclinic.org)
  • The second procedure, also known as the Nesbit procedure, shortens the normal side of the penis to balance the shortening due to scar on the opposite side. (clevelandclinic.org)
  • Yet when he's not boasting to other men, the average man significantly underestimates the relative size of his penis. (webmd.com)
  • Any man who is actually interested in making a woman feel physically uncomfortable while having sex , due solely to the size of his penis, is missing the whole point of sex , isn't he? (everything2.com)
  • Just about every man-regardless of the actual size of his penis-worries about being too small. (lifehacker.com)
  • Below, the parts of the penis are labeled from base to tip: Sheath, chelicera, truncus, glans and stylus. (livescience.com)
  • In rare cases, surgery may be required to avoid permanent damage to the penis. (medicinenet.com)
  • It is important to get prompt treatment to avoid damage to the penis. (clevelandclinic.org)
  • Using surgery to avoid permanent damage to the penis if these above measures fail. (clevelandclinic.org)
  • But overusing a penis pump can damage the tissue of the penis, leading to weaker erections. (www.nhs.uk)
  • Once it spreads to the deeper surrounding tissue of the penis or to the lymph nodes, that number drops to 59 percent. (healthline.com)
  • Although you may see guys with penises that are bigger or smaller than yours, it is very likely that your penis is a normal size. (kidshealth.org)
  • The way that averages work means that it's very likely that your penis is of average size. (redorbit.com)
  • In the ventral aspect, the superficial fascia of the penis along with the skin makes a well-defined penoscrotal angle below which the dartos fascia starts getting incorporated with more smooth muscle fibers and is closely adherent to the skin of the scrotal wall. (hindawi.com)
  • In addition to the bending of the penis, Peyronie's disease can cause general pain as well as painful erections. (medicinenet.com)
  • Controversies in ilioinguinal lymphadenectomy for cancer of the penis. (springer.com)
  • Penis cancer is a disease in which malignant ( cancer ) cells form in the tissues of the penis. (medicinenet.com)
  • Both sides agree that Seaton had squamous cell carcinoma, a type of skin cancer, in his penis. (yahoo.com)
  • The first, as Cindolo and his colleagues address in their research, is simply that some primary care providers may not be familiar with cancer of the penis because of its rarity. (healthline.com)
  • The jury unanimously found that Dr. John Patterson exercised appropriate care when he removed a portion of Seaton's penis after finding cancer and ruled 10-2 against Seaton's claim that Patterson did not properly obtain consent to him before removing his penis. (go.com)
  • The tip of Seaton's penis "had the appearance of rotten cauliflower" because it was so inundated with cancer, Robinson told the courtroom on Monday. (go.com)
  • Precancerous conditions of the penis are changes to penis cells that make them more likely to develop into cancer. (cancer.ca)
  • It is sometimes referred to as a low-grade cancer related to verrucous carcinoma of the penis. (cancer.ca)
  • However, the penis gets a richer supply, generating stronger and fuller erections, which last longer. (bartleby.com)
  • There is also significant overlap between techniques intended to enlarge the penis and techniques intended to achieve other, related objectives, such as reversing impotence, extending the duration of erections, or enhancing sexual climax. (wikipedia.org)
  • The glans is the enlarged tip of the penis that contains the urethral orifice where semen and urine exit the body. (innerbody.com)
  • Are girls attracted to a boy's penis? (answers.com)
  • Most heterosexual girls are attracted to a boy's penis, as well as most of the defining physical attributes of masculinity. (answers.com)
  • Can a boy's penis fall off? (answers.com)
  • What does a boy's penis look like? (answers.com)
  • Can girls touch the boy's penis? (answers.com)
  • Can a boy's penis go on a girl? (answers.com)
  • Why does a boy's penis stick up? (answers.com)
  • How can you tell if a boy's penis big? (answers.com)
  • How do you touch a boy's penis? (answers.com)
  • How big is the average boy's penis? (answers.com)
  • The important takeaway here is that the exact time when a boy's penis starts to grow during puberty can vary quite widely. (redorbit.com)
  • Also, like his feet, a guy's penis may appear smaller to him just because the perspective is different when he's looking down. (kidshealth.org)
  • In addition to size, guys also wonder about other aspects of how their penises look, such as whether the skin covering the penis is normal or if it's OK for a guy's penis to hang to the left or right (it is! (kidshealth.org)
  • Despite what you may hear or read, no special exercises, supplements, or diets will change a guy's penis size. (kidshealth.org)
  • Usually by the end of puberty, a guy's penis has reached its expected size. (kidshealth.org)
  • For example, a guy might wonder if the skin covering the penis is normal or if it's OK for a guy's penis to hang to the left or right (it is! (kidshealth.org)
  • Such organs occur in many animals, both vertebrate and invertebrate, but males do not bear a penis in every animal species, and in those species in which the male does bear a so-called penis, the penes in the various species are not necessarily homologous. (wikipedia.org)
  • For example, the penis of a mammal is at most analogous to the penis of a male insect or barnacle. (wikipedia.org)
  • Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. (wikipedia.org)
  • The male tinamou has a corkscrew shaped penis, similar to those of the ratites and to the hemipenis of some reptiles. (wikipedia.org)
  • [8] As a result of the submissive behavior in males, it was hypothesized that the male hyena erected its penis as a show of submissiveness. (wikipedia.org)
  • The penis in the male is the homologue of the clitoris in the female. (everything2.com)
  • Do female doctors touch male patients on the penis? (answers.com)
  • So, if the penis doesn't inflate, how does the male alligator extrude it from the cloaca? (nationalgeographic.com)
  • There have been a lot of changes happened over the past decade about the subject of penis size and male sexual pleasure, in general. (scoop.it)
  • The glans penis , more commonly referred to as the glans , is a structure at the distal end of the penis in male mammals . (wikipedia.org)
  • Male felids are able to urinate backwards by curving the tip of the glans penis backward. (wikipedia.org)
  • In male dogs, the glans penis consists of two parts called the bulbus glandis and pars longa glandis . (wikipedia.org)
  • Alternatively, they could get flushed or scooped out by the penis of another male. (nationalgeographic.com)
  • Unlike pills, natural penis enhancement does not want special supplement or DMax Male Enhancement Review Male Enhancement Price product. (dailystrength.org)
  • During puberty, the penis lengthens. (medlineplus.gov)
  • The penis grows the most during puberty . (kidshealth.org)
  • It all depends on age im 18 and when i hit puberty at the start of year 8 (age 12 from the August, 1 month before starting year 8) my penis was about 2.5-3.5 flacid (not erect … ) and 3.5-4.5 erected. (answers.com)
  • Christian Sonne at Aarhus University, Denmark, and colleagues had previously shown that polar bears with high levels of pollutants called organohalogens in their bodies had both smaller testes and a smaller penis bone. (newscientist.com)
  • Just the penis will be transplanted, not the testes, where sperm are produced. (nytimes.com)
  • The vacuum draws blood into the penis and makes it swell. (www.nhs.uk)
  • While you can't do much to safely enlarge your penis, there are several things you can do to make you feel more confident about your body. (www.nhs.uk)
  • This will only enlarge your penis temporarily. (urbandictionary.com)
  • I started realizing my penis had phimosis and i fixed it relatively quick by stretching excercises. (scarleteen.com)
  • Now my only concern is ever since i fixed my phimosis my foreskin does not roll all the way to the top and doesn't cover the tip of my penis anymore. (scarleteen.com)
  • The successes of the Vimax Penis Pills are contained in the penis patch. (bartleby.com)
  • Please join this discussion about Penis pills within the Elite Between the Sheets category. (elitefitness.com)
  • Anyone ever actually try penis enlargment pills? (elitefitness.com)
  • Anyone tried penis enlarging pills? (elitefitness.com)
  • While some penis sores will clear up on their own, many require treatment to prevent symptoms from getting worse, complications, and transmission to others. (medicalnewstoday.com)
  • Its symptoms can include painful, itchy, fluid-filled, blistering sores on the penis and other parts of the genitals. (medicalnewstoday.com)
  • It is theorized that the remarkable size of their spiny penises with bristled tips may have evolved in response to competitive pressure in these highly promiscuous birds, removing sperm from previous matings in the manner of a bottle brush. (wikipedia.org)
  • Ejaculation is the release of sperm-containing fluid from the penis during an orgasm. (medlineplus.gov)
  • If the penis gets wet and has sperm it could go inside girl and make her pregnant. (answers.com)
  • Sperm travels along a deep groove running the length of the penis, which is surrounded by dense tissue. (nationalgeographic.com)
  • Indeed, when Sekizawa looked at the detached penises under a microscope, she found that they are covered by many backward-pointing spines, which had entangled many sperm. (nationalgeographic.com)
  • If Neotrogla males need to spend valuable resources producing their sperm packets, it's likely they would be choosy about their mates, Yoshizawa says, which would help explain why the females have evolved a penis well designed to hold down reluctant mates long enough to wring out all their gifts. (scientificamerican.com)
  • The disease can happen if bleeding inside the penis starts after you bend or hit it, if you have a connective tissue disorder, or if you have an inflammation of your lymphatic system or blood vessels. (healthline.com)
  • Two other successful penis transplants have been performed in the past - one in South Africa in 2014 and anotherat the Massachusetts General Hospital in the US in 2016. (news.com.au)
  • Manning is just the third man in the world to receive a new penis, following transplants in South Africa in 2014 and China in 2005. (theindychannel.com)
  • Only two other penis transplants have been reported in medical journals: a failed one in China in 2006 and a successful one in South Africa last year. (nytimes.com)
  • Some doctors have criticized the idea of penis transplants, saying they are not needed to save the patient's life. (nytimes.com)
  • The suspension of the penis and the attachments of its skin and subcutaneous fascia are described well in the literature. (hindawi.com)
  • This superficial fascia extends into the preputial skin and is fixed at the base of the glans penis in the coronal sulcus. (hindawi.com)
  • On the other hand, if the superficial fascia adherent to the deeper fascia is more lax normal at the base of the penis, this makes the penile skin look redundant and overhang the penis thus burying the penis. (hindawi.com)
  • They are more common on areas of skin with lots of pores, such as the face, chest, and back, but they can also occur on the penis. (medicalnewstoday.com)
  • Sores can appear on any part of the skin, including on the penis. (medicalnewstoday.com)
  • Scabies is a contagious skin condition that can affect many parts of the body, including the penis. (medicalnewstoday.com)
  • Almost all penile cancers begin in the skin of the penis. (medicinenet.com)
  • Deep to the skin of the penis is a layer of subcutaneous tissue containing blood vessels and protein fibers that loosely anchor the skin to the underlying tissue. (innerbody.com)
  • If penis skin is sensative and irritate when touch it then it will give hurt.Otherwise there nothing to get hurt. (answers.com)
  • There is itching below the skin of my penis. (askmehelpdesk.com)
  • These both treat and prevent a number of penis skin irritation. (yahoo.com)
  • A retractile penis device comprises an apertured plate carrying an inflatable toroid ring, the ring being substantially aligned with the aperture and acting in use when inflated to apply pressure to the base of the penis and the surrounding skin area of the wearer. (google.es)
  • Also, if the person in question is significantly overweight or has a great deal of belly fat (or what's sometimes referred to as an "apron" of fat and skin on the belly that hangs over the waist), it could obscure the penis to some extent. (scarleteen.com)
  • Fat can be injected under the skin of the penis, but generally this ends up simply resulting in a lumpy penis since the fat tends to accumulate in spots. (scarleteen.com)
  • PeIN refers to abnormal cell changes, called carcinoma in situ , that occur on the skin surface of the penis. (cancer.ca)