Difficult or labored breathing.
A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.
Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.
The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an EXERCISE TEST.
A disorder characterized by sudden attacks of respiratory distress in at rest patients with HEART FAILURE and PULMONARY EDEMA. It usually occurs at night after several hours of sleep in a reclining position. Patients awaken with a feeling of suffocation, coughing, a cold sweat, and TACHYCARDIA. When there is significant WHEEZING, it is called cardiac asthma.
Measure of the maximum amount of air that can be expelled in a given number of seconds during a FORCED VITAL CAPACITY determination . It is usually given as FEV followed by a subscript indicating the number of seconds over which the measurement is made, although it is sometimes given as a percentage of forced vital capacity.
Measurement of volume of air inhaled or exhaled by the lung.
The volume of air that is exhaled by a maximal expiration following a maximal inspiration.
Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
These include the muscles of the DIAPHRAGM and the INTERCOSTAL MUSCLES.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
Any hindrance to the passage of air into and out of the lungs.
The maximum volume of air that can be inspired after reaching the end of a normal, quiet expiration. It is the sum of the TIDAL VOLUME and the INSPIRATORY RESERVE VOLUME. Common abbreviation is IC.
X-ray visualization of the chest and organs of the thoracic cavity. It is not restricted to visualization of the lungs.
Therapeutic exercises aimed to deepen inspiration or expiration or even to alter the rate and rhythm of respiration.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.
Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
Analogs or derivatives of scopolamine.
Inhalation of oxygen aimed at restoring toward normal any pathophysiologic alterations of gas exchange in the cardiopulmonary system, as by the use of a respirator, nasal catheter, tent, chamber, or mask. (From Dorland, 27th ed & Stedman, 25th ed)
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of PULMONARY ALVEOLI that extends to the interstitium and beyond leading to diffuse PULMONARY FIBROSIS. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Pathological processes involving any part of the LUNG.
Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Expectoration or spitting of blood originating from any part of the RESPIRATORY TRACT, usually from hemorrhage in the lung parenchyma (PULMONARY ALVEOLI) and the BRONCHIAL ARTERIES.
The physical or mechanical action of the LUNGS; DIAPHRAGM; RIBS; and CHEST WALL during respiration. It includes airflow, lung volume, neural and reflex controls, mechanoreceptors, breathing patterns, etc.
Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Disease having a short and relatively severe course.
The act of BREATHING in.
RESPIRATORY MUSCLE contraction during INHALATION. The work is accomplished in three phases: LUNG COMPLIANCE work, that required to expand the LUNGS against its elastic forces; tissue resistance work, that required to overcome the viscosity of the lung and chest wall structures; and AIRWAY RESISTANCE work, that required to overcome airway resistance during the movement of air into the lungs. Work of breathing does not refer to expiration, which is entirely a passive process caused by elastic recoil of the lung and chest cage. (Guyton, Textbook of Medical Physiology, 8th ed, p406)
Endoscopic examination, therapy or surgery of the bronchi.
A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
Measure of the maximum amount of air that can be breathed in and blown out over a sustained interval such as 15 or 20 seconds. Common abbreviations are MVV and MBC.
The amount of a gas taken up, by the pulmonary capillary blood from the alveolar gas, per minute per unit of average pressure of the gradient of the gas across the BLOOD-AIR BARRIER.
The volume of air remaining in the LUNGS at the end of a maximal expiration. Common abbreviation is RV.
Enlargement of air spaces distal to the TERMINAL BRONCHIOLES where gas-exchange normally takes place. This is usually due to destruction of the alveolar wall. Pulmonary emphysema can be classified by the location and distribution of the lesions.
Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (= OXYGEN CONSUMPTION) or cell respiration (= CELL RESPIRATION).
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
The volume of air contained in the lungs at the end of a maximal inspiration. It is the equivalent to each of the following sums: VITAL CAPACITY plus RESIDUAL VOLUME; INSPIRATORY CAPACITY plus FUNCTIONAL RESIDUAL CAPACITY; TIDAL VOLUME plus INSPIRATORY RESERVE VOLUME plus functional residual capacity; or tidal volume plus inspiratory reserve volume plus EXPIRATORY RESERVE VOLUME plus residual volume.
Tests involving inhalation of allergens (nebulized or in dust form), nebulized pharmacologically active solutions (e.g., histamine, methacholine), or control solutions, followed by assessment of respiratory function. These tests are used in the diagnosis of asthma.
Endogenous or exogenous chemicals that regulate the WATER-ELECTROLYTE BALANCE in the body. They consist of peptides and non-peptide compounds.
The extra volume of air that can be expired with maximum effort beyond the level reached at the end of a normal, quiet expiration. Common abbreviation is ERV.
An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
Pressure, burning, or numbness in the chest.
Most patients are young adult males between the age of 20-40. Common clinical presentations include fever, cough, dyspnea and ...
Common symptoms include cough, dyspnea, weight loss, and debility. Over 70% of patients with small-cell carcinoma present with ... Oryzon Genomics "ORY-1001 - Patient Info" , https://www.oryzon.com/en/patient/patient-information Cure Magazine "Keytruda Shows ... In this study, patients with ES-SCLC were treated with standard carboplatin plus etoposide and were randomized to receive ... For patients who relapse in < 6 months, single-agent chemotherapy either topotecan second-line therapy, or paclitaxel can be ...
By treating patients with a combination of Demcizumab and a cytotoxic chemotherapy, it is hoped that a more durable anti-tumor ... More adverse effect are nausea, hypoalbuminemia, dizziness, and dyspnea occurred. Finally, some uncommon side effects are heart ... The patients were similar to subjects in phase 1 trials of demcizumab. The Yosemite trial is a double blind, randomized, 3 arm ... They dosed fifty-five patients either weekly with a doses ranging from .5 to 5 mg/kg or dosed biweekly with doses ranging from ...
Leung, P; Jubran, A; Tobin, MJ (Jun 1997). "Comparison of assisted ventilator modes on triggering, patient effort, and dyspnea ... If the patient maintains the minute volume settings for VT x f, no mandatory breaths are delivered. If the patient's minute ... Some studies have shown an increase in patient work of breathing when switched from CMV to SIMV, and others have demonstrated ... The ventilator varies the tidal volume and pressure based on the patients work of breathing, the amount it delivers is ...
Marantz P, Kaplan M, Alderman M (1990). "Clinical diagnosis of congestive heart failure in patients with acute dyspnea". Chest ... The patient is asked to lie down at 30 degrees with his/her head tilted 45 degrees to the left. Then an oblique light is used ... In patients with severe right heart congestion, observation of the inner jugular might not be feasible due to its distention ... Does this patient have abnormal central venous pressure?". JAMA. 275 (8): 630-4. doi:10.1001/jama.1996.03530320054034. PMID ...
Respiratory failure - CAP patients often have dyspnea, which may require support. Non-invasive machines (such as bilevel ... Hospitalized patients have an average mortality rate of 12 percent, with the rate rising to 40 percent for patients with ... Intensive-care patients at risk for pseudomonas aeruginosa: These patients require antibiotics targeting this difficult-to- ... Some patients with CAP will be at increased risk of death despite antimicrobial treatment. A key reason for this is the host's ...
Baldwin J, Cox J (September 2016). "Treating Dyspnea: Is Oxygen Therapy the Best Option for All Patients?". The Medical Clinics ... Neuendorf R, Harding A, Stello N, Hanes D, Wahbeh H (August 2016). "Depression and anxiety in patients with Inflammatory Bowel ... "Strategies to improve anxiety and depression in patients with COPD: a mental health perspective". Neuropsychiatric Disease and ... region and reduced serotonin type 1A receptor binding in the anterior and posterior cingulate and raphe of patients are the ...
Evaluation of dyspnea. Work up before heart transplantion. Prognosis and risk assessment of heart failure patients. The test is ... Cardiac stress tests compare the coronary circulation while the patient is at rest with the same patient's circulation during ... if the patient is actively wheezing then the physician should determine the benefits versus the risk to the patient of ... If the patient's Asthma is treated with an inhaler then it should be used as a pre-treatment prior to the injection of the ...
Around 90% of patients with preserved AV conduction have intact VA conduction, and about 30-40% of patients with complete AV ... Heart failure - Dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and edema. Hypotension - Seizure, mental status change, ... For patients with autonomic insufficiency, a high-salt diet may be appropriate. For patients with dehydration, oral fluid ... can improve the patient's symptoms.[citation needed] Several cases mentioned below: For patients with heart failure, low-salt ...
Brack T, Jubran A, Tobin MJ (May 2002). "Dyspnea and decreased variability of breathing in patients with restrictive lung ... Due to the chronic nature of this disease, the leading symptom of restrictive lung disease is progressive exertional dyspnea. ... Comparison Of Various Pulmonary Function Parameters In The Diagnosis Of Obstructive Lung Disease In Patients With Normal Fev1/ ...
About 20% of DIPNECH patients are symptom free at the time they first present. The most common symptoms include:[5][6][7] ... Shortness of breath or dyspnea when exercising or exerting one's self. *Wheezing (less frequent) ... Some patients have been treated with somatostatin analogs. Although the cough associated with DIPNECH tends to diminish on this ... Erroneous initial diagnoses of asthma or chronic obstructive pulmonary disease often are made in patients with DIPNECH.[8] ...
In chronic HP, patients often lack a history of acute episodes. They have an insidious onset of cough, progressive dyspnea, ... Patients with subacute HP gradually develop a productive cough, dyspnea, fatigue, anorexia, weight loss, and pleurisy. Symptoms ... In addition, many patients have hypoxemia at rest, and all patients desaturate with exercise. Hypersensitivity pneumonitis ... Pulmonary function tests show reduced diffusion capacity of lungs for carbon monoxide (DLCO). Many patients have hypoxemia at ...
Al-Herz A, Snip JP, Clark B, Esdaile JM (February 2008). "Exercise therapy for patients with diffuse idiopathic skeletal ... Psychogios, Georgios; Jering, Monika; Zenk, Johannes (2018). "Cervical Hyperostosis Leading to Dyspnea, Aspiration and ... Note the preponderance on the patient's left side (right side of image). Ectopic calcification and new bone formation in ... difficulty swallowing or even dyspnea. Similar calcification and ossification may be seen at peripheral entheseal sites, ...
Patients receiving monoamine oxidase inhibitors. For shock due to loss of blood or fluid, give fluid replacement therapy ... Nausea, vomiting, reduced appetite, urinary retention, dyspnea, weakness. Potentially fatal reactions are due to ... For hypotension secondary to spinal anaesthesia in obstetric patients, the dose for adults is 15 mg as a single dose, repeated ... with the rate and duration of administration depending on the patient's response. ...
A common symptom that many terminal patients experience is dyspnea, or difficulty with breathing. To ease this symptom, doctors ... patients in hospice care often live the same length of time as patients in the hospital. A study of 3850 liver cancer patients ... it is recommended that patients, doctors, and families all convene and discuss the patient's decisions before the patient ... A patient who has such an illness may be referred to as a terminal patient, terminally ill or simply as being terminal. There ...
At first the patient experiences a burning sensation in the mouth, throat and stomach. After a few days the person will suffer ... Acute toxic symptoms include vomiting, diarrhea, skin irritation, itching, rash, blisters, bleeding and dyspnea. If the ... Otherwise the patient will die of bronchial pneumonia and lung bleeding. T-2 mycotoxin is also toxic to animals. The compound ...
Patients on morphine sometimes say they have insomnia, visual hallucinations and nightmares;[1] if these occur then reduction ... In nebulised form, for treatment of dyspnoea. The evidence for efficacy is slim[1]. Evidence is better for other routes [2]. ...
Patients with giant bullae filling half the thoracic volume and compressing relatively normal adjacent parenchyma are ... It is also indicated in severe dyspnea, repeated respiratory infections and spontaneous pneumothorax. The size of dilated air- ... 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease". ... "Bullectomy is comparable to lung volume reduction in patients with end-stage emphysema". European Journal of Cardio-Thoracic ...
In the case of stroke patients, monitoring in the recovery phase seems to be achievable by measurement of both the ICG ... Effects such as anaphylactic shock, hypotension, tachycardia, dyspnea and urticaria only occurred in individual cases; the risk ... "Assessment of cerebral perfusion in post-traumatic brain injury patients with the use of ICG-bolus tracking method". NeuroImage ... of severe side-effects rises in patients with chronic kidney impairment. The frequencies of mild, moderate and severe side- ...
Most people have dyspnea on exertion with daily activities by 10 years after symptom onset. Many patients require supplemental ... of patients with TSC-LAM. Hepatic AMLs were present in 2% of patients with S-LAM and 33% of patients with TSC-LAM. Ascites was ... The typical disease course displays progressive dyspnea on exertion, spaced by recurrent pneumothoraces and in some patients, ... One study CT imaged 256 patients with S-LAM and 67 with TSC-LAM. Renal AMLs were present in 32% of patients with S-LAM and 93% ...
The symptomatic patient may present with dyspnea, cyanosis, chest pain, pulsus paradoxus, bradycardia or tachycardia.[citation ... On physical examination, the patient may have the classic "Beck's triad" - hypotension, raised JVP and distant heart sounds, ...
In patients with severe lung hyperinflation, IPPB may decrease dyspnea and discomfort during nebulized therapy. Most ... and in some circumstances ventilate the patient. IPPB may be indicated for patients who are at risk for developing atelectasis ... Shelledy DC, Mikles SP (2001). "Patient assessment and respiratory care plan development.". In Mishoe SC, Welch MA Jr (eds.). ... ISBN 978-0-07-134474-6. Janssens JP, de Muralt B, Titelion V (2000). "Management of dyspnea in severe chronic obstructive ...
In some cases, dyspnea persists for an indefinite period. Contusion can also permanently reduce the compliance of the lungs. ... CT scanning also helps determine the size of a contusion, which is useful in determining whether a patient needs mechanical ... Dyspnea (painful breathing or difficulty breathing) is commonly seen, and tolerance for exercise may be lowered. Rapid ... As late as four years post-injury, decreased functional residual capacity has been found in most pulmonary contusion patients ...
Patients may remain asymptomatic after acid aspiration. Others may develop dyspnea, pleuritic chest pain, cough, fever, bloody ... Also increased pneumonia risk exists in patients with esophageal dysphagia when compared to stroke patients because patients ... Older patients may have impaired T cell function and hence, they may be unable to mount a febrile response. The mucociliary ... For example, patients with advanced COPD tend to develop enlarged lungs, resulting in compression of the esophagus and thus ...
Patients should be asked about symptoms of hemodynamic compromise, including dyspnea, chest pain, lightheadedness, and fatigue ... as most patients should undergo colonoscopy.[citation needed] Colonoscopy is the test of choice in the majority of patients ... If a patient is suspected of having severe blood loss they will most likely be placed on a vital sign monitor and administered ... It is most likely that a surgical consult will be ordered if the patient is unable to be stabilized by non-invasive techniques ...
Patient-guided nutrition is suggested. In patients with Wernicke-Korsakoff syndrome, even higher doses of parenteral thiamine ... There may be tachycardia, dyspnea, chest pain, orthostatic hypotension, changes in heart rate and blood pressure. The lack of ... Around 10% of patients exhibit all three features, and other symptoms may also be present. While it is commonly regarded as a ... In patients suspected of WE, thiamine treatment should be started immediately. Blood should be immediately taken to test for ...
There is a high incidence of talaromycosis in AIDS patients in SE Asia; 10% of patients in Hong Kong get talaromycosis as an ... The respiratory system is commonly involved as well; cough, fever, dyspnea, and chest pain may be present, reflecting the ... The patient's history also is a diagnostic help. If they have traveled to Southeast Asia and are HIV-positive, then there is an ... One study of 550 AIDS patients showed that the incidence was higher during the rainy season, which is when the rats breed. But ...
The procedure is discontinued if the patient complains of headache, discomfort, dizziness, palpitations, fatigue, or dyspnea. ... Frames, tilt tables, and pillows may be used to support patients in these positions. Up to 12 postures may be used. Patients ... Patients may be dyspnic after the various manuovers, since the head-down position increases the work of breathing, reduces ... These positions can be modified depending on the patient's condition. Postural drainage may be followed by breathing exercises ...
... patients are subject to recurrent, severe attacks. The cardinal symptoms of an asthma attack are shortness of breath (dyspnea ... There are two subtypes divided by symptoms: Type 1 and Type 2, depending on the stability of the patient's maximum speed of ... Since catastrophic attacks are unpredictable in type 2, patients may display identification of the issue, such as a MedicAlert ...
The most common side effect is conjunctival hyperemia, which occurs in 4 to 20% of patients. Less common side effects include ... Rare side effects are dyspnoea (breathing difficulties), worsening of asthma, and macular oedema. Nonsteroidal anti- ...
"Is epistaxis evidence of end-organ damage in patients with hypertension?". Laryngoscope. 109 (7): 1111-1115. doi:10.1097/ ...
... is preferred by doctors for patients who are at risk of suicide, due to moclobemide's low toxicity in overdose.[100] Patients ... Dyspnoea. *Visual disturbances. *Increased hepatic enzymes without associated clinical sequelae.. Contraindications[edit]. ... Use in children is not recommended as there is insufficient data to assess their safety and efficacy in these patients.[10][11] ... However, patients with significantly reduced liver function require dose reductions due to the significant slowing of ...
Craig JA (2012). Ferri's netter patient advisor (2nd ed.). Saunders. p. 913. ISBN 9781455728268. . Traditionally, two types of ... Mahler DA (May 2006). "Mechanisms and measurement of dyspnea in chronic obstructive pulmonary disease". Proceedings of the ... Torres M, Moayedi S (May 2007). "Evaluation of the acutely dyspneic elderly patient". Clinics in Geriatric Medicine. 23 (2): ... March 2020). "Pharmacologic Therapies in Patients With Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic ...
Some patients rapidly recover from ALI and have no permanent sequelae. Prolonged inflammation and destruction of pneumocytes ... With increased exposure, symptoms may progress to labored respirations, severe coughing, chest tightness, wheezing, dyspnea, ... A minority of these patients develop late pulmonary fibrosis. Also at enhanced risk are persons with co-morbidities. Several ... Positive end-expiratory pressure (PEEP) is used in mechanically ventilated patients with ARDS to improve oxygenation. ...
Most patients recover fully, remain stable, or show slow recovery, but the disease is fatal in up to 5% of patients. ... Fatigue is present to some degree, while the muscle pain (which may be extremely intense) and dyspnea continue in this phase.[8 ... Analysis of four patients and implications for differential diagnosis and pathogenesis". Archives of Internal Medicine. 150 (10 ... Goronzy JJ, Weyand CM (July 1990). "Eosinophilia, myopathy, and neuropathy in a patient with repeated use of L-tryptophan". ...
Baldwin, Jennifer; Cox, Jaclyn (September 2016). "Treating Dyspnea". Medical Clinics of North America. 100 (5): 1123-1130. doi: ... Neuendorf R, Harding A, Stello N, Hanes D, Wahbeh H (2016). "Depression and anxiety in patients with Inflammatory Bowel Disease ... "Strategies to improve anxiety and depression in patients with COPD: a mental health perspective". Neuropsychiatr Dis Treat ... region and reduced serotonin type 1A receptor binding in the anterior and posterior cingulate and raphe of patients are the ...
... of ALS patients and up to 50% of FTD patients.[54] Other genes known to cause FTD-ALS include CHCHD10, SQSTM1, and TBK1.[49] ... About 90% of people with ALS die peacefully.[110] In the final days of life, opioids can be used to treat pain and dyspnea, ... "Stephen Hawking serves as role model for ALS patients". CNN. 20 April 2009. Archived from the original on 15 August 2016.. ... Connolly S, Galvin M, Hardiman O (April 2015). "End-of-life management in patients with amyotrophic lateral sclerosis". The ...
100,0 100,1 Shiber J. R., Santana J. (May 2006)։ «Dyspnea»։ Med. Clin. North Am. 90 (3): 453-79։ PMID 16473100։ doi:10.1016/j. ... The influence of smoking on the treatment response in patients with asthma»։ Current Opinion in Allergy and Clinical Immunology ... Dahl R (August 2006)։ «Systemic side effects of inhaled corticosteroids in patients with asthma»։ Respir Med 100 (8): 1307-17։ ... von Mutius E, Drazen, JM (Mar 1, 2012)։ «A patient with asthma seeks medical advice in 1828, 1928, and 2012»։ New England ...
... giving it to the patient, and observing the patient for signs or symptoms of an allergic reaction.[medical citation needed] ... This results in rhinorrhea, itchiness, dyspnea, and anaphylaxis. Depending on the individual, the allergen, and the mode of ... If a person's RAST score is higher than the predictive value for that food, over a 95% chance exists that patients will have an ... Lactose intolerance generally develops later in life, but can present in young patients in severe cases. It is due to an enzyme ...
a b Shiber JR, Santana J (May 2006). "Dyspnea". Med. Clin. North Am. 90 (3): 453-79. PMID 16473100. doi:10.1016/j.mcna.2005.11. ... Thomson NC, Spears M (2005). "The influence of smoking on the treatment response in patients with asthma". Curr Opin Allergy ... Dahl R (August 2006). "Systemic side effects of inhaled corticosteroids in patients with asthma". Respir Med 100 (8): 1307-17. ... von Mutius, E; Drazen, JM (2012 Mar 1). "A patient with asthma seeks medical advice in 1828, 1928, and 2012.". New England ...
The patient had been previously exposed to two canine bites on two consecutive days from two different dogs. Noting the ... dyspnea, headaches, and skin rashes such as exanthema. More severe cases of endocarditis, DIC, and meningitis have been ... In incidents where the patient is in full septic shock, whole blood smears may be effective. Immediate cleansing of wounds ... Immunosuppressed patients make up approximately 5% of individuals presenting with C. canimorsus symptoms. Symptoms appear ...
... of hypertensive emergency patients, two-organ involvement in about 14% of patients, and multi-organ failure (failure of at ... Dyspnea. *Fainting or the sensation of the world spinning around them. *Severe anxiety ... Commonly, ischemic heart attack and stroke are the causes that lead to death in patients with severe hypertension. It is ... The most common cause in patients with diagnosed, chronic hypertension who have discontinued anti hypertensive medications.[6] ...
Sibel Cıngı, a 73-year-old lung cancer patient with a prior lung surgery, was exposed to extreme amount of tear gas inside her ... apartment after a canister was shot through her window on 16 June, leading to complications such as dyspnea and arrhythmia. ...
A sign has the potential to be objectively observed by someone other than the patient, whereas a symptom does not. There is a ... Clinical signs such as rash and muscle tremors are objectively observable both by the patient and by anyone else. Some signs ... Some symptoms can be misleading to the patient or the medical practitioner caring for them. For example, inflammation of the ... A sign observed by the patient last week but now gone (such as a resolved rash) was a sign, but it belongs to the medical ...
Therefore, in patients with chronic mitral stenosis, pulmonary capillary pressures of 40 to 45 mm Hg have been measured without ... Although hypoxemia normally stimulates ventilation and produces dyspnea, these phenomena and the other symptoms and signs of ... Although the severity of airflow obstruction as measured by FEV1 is the best correlate with overall prognosis in patients with ... Large-scale studies of LTOT in patients with COPD have demonstrated a dose-response relationship between daily hours of oxygen ...
The Food and Drug Administration approved the vagus nerve stimulator in 1997 as a way to control seizures in some patients with ... Engleman EG, Lankton J, Lankton B (December 1971). "Granulated sugar as treatment for hiccups in conscious patients". The New ... "Retrospective analysis of hiccups in patients at a community hospital from 1995-2000". J Natl Med Assoc. 94 (6): 480-3. PMC ... had some success with an experimental procedure in which a vagus nerve stimulator is implanted in the upper chest of patients ...
If necessary, patients may be given additional analgesics for the procedure. Once the tube is in place it is sutured to the ... Minor complications include a subcutaneous hematoma or seroma, anxiety, shortness of breath (dyspnea), and cough (after ... This allows patients with pneumothorax to remain more mobile. British Thoracic Society recommends the tube is inserted in an ... If a chest tube clogs when there is an airleak the patient will develop a pneumothorax. This can be life threatening. [10] Here ...
... patients who have asthma or COPD or patients who have peptic ulcer disease. Also patients with an obstruction in the ... Bronchoconstriction leads to asthmatic attacks and severe dyspnea, and bradycardia combined with marked hypotension and ... Muscarine is contraindicated in patients with diseases that make them susceptible to parasympathetic stimulation, ...
... a disorder of the autonomic nervous system in which a patient must consciously breathe; although it is often said that persons ...
... should be used with caution in patients with inadequate fluid replacement, impaired adrenal function, hypoxia, ... Respiratory: dyspnea, pulmonary edema. *Miscellaneous: dizziness, headache, tremor, hyperglycemic reactions, dry mouth ... 300-3000 µg/l in abusers or poisoned patients and 3-20 mg/l in cases of acute fatal overdosage. The current WADA limit for ...
Carbon dioxide is a by-product of food metabolism and in high amounts has toxic effects including: dyspnea, acidosis and ... "Prediction of arterial blood gas values from venous blood gas values in patients with acute respiratory failure receiving ... "Correlation of simultaneously obtained capillary, venous, and arterial blood gases of patients in a paediatric intensive care ...
Patients who have uremia often have poor or absent appetite, vomiting and nausea. This can cause weight loss. ... and the difficulty of eating with dyspnea (labored breathing).[53] ... As chronic obstructive pulmonary disease (COPD) advances, about 35% of patients experience severe weight loss called pulmonary ... Cancers to suspect in patients with unexplained weight loss include gastrointestinal, prostate, hepatobiliary (hepatocellular ...
2012) [66] which showed that a patient who suffered bilateral lesions of the insula cortex expressed the full complement of ... One brain imaging study suggests that the unpleasantness of subjectively perceived dyspnea is processed in the right human ... "The Unpleasantness of Perceived Dyspnea Is Processed in the Anterior Insula and Amygdala". American Journal of Respiratory and ... anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients ...
Headaches are also a symptom of dyspnea in patients suffering from anaemia. Some patients report a numb sensation in their head ... dyspnea. dys- + -pnea. /dɪspˈniːə/ disp-NEE-ə,[37][38][39] /ˈdɪspniə/ DISP-nee-ə[36][35] ... Look up dyspnea, dyspnoea, breathlessness, or respiratory distress in Wiktionary, the free dictionary. ... Shortness of breath (SOB), also known as dyspnea (BrE: dyspnoea) is a feeling of not being able to breathe well enough. The ...
It is important for patients to discontinue the use of tretinoin due to the elevation of white blood cells and possible low ... The syndrome is characterized by dyspnea, fever, weight gain, hypotension, and pulmonary infiltrates. This is effectively ... Subsequently, so-called RAS was recognized in APML patients who had been treated with another highly efficacious drug, arsenic ... Retinoic acid syndrome (RAS) is a potentially life-threatening complication observed in patients with acute promyelocytic ...
An uncooperative patient or a coagulation disorder that cannot be corrected are relative contraindications.[7] Routine ... Minor complications include a dry tap (no fluid return), subcutaneous hematoma or seroma, anxiety, dyspnea and cough (after ... then this procedure can also be used therapeutically to remove that fluid and improve patient comfort and lung function. ... "SAfety of ultrasound-guided thoracentesis in patients with abnormal preprocedural coagulation parameters". Chest. 144 (2): 456 ...
2000). "Diabetic patients have a decreased incidence of acute respiratory distress syndrome". Crit Care Med. 28 (7): 2187-92. ... acute onset, persistent dyspnea. *bilateral infiltrates on chest radiograph consistent with pulmonary edema ... A patient with ARDS, on average, spends between 8 and 11 days on a mechanical ventilator; APRV may reduce this time ... Pneumonia and sepsis are the most common triggers, and pneumonia is present in up to 60% of patients and may be either causes ...
... an infection of the lungs not related to the medicinal drugs the patient is taking. But if the patient is taking such a ... An 82-year-old man with dyspnea and pulmonary abnormalities. N Engl J Med. 2003 Apr 17;348(16):1574-85. Meadors M, Floyd J, ... Most patients with AIPT respond well to the withdrawal of amiodarone and to the addition of corticosteroid treatment, which is ... Lung symptoms in a patient who is taking a medicinal drug that can cause pulmonary toxicity should not automatically lead to a ...
In 2011, a large Danish epidemiological study found an increased risk of lung cancer for patients who lived in areas with high ... Sufferers have severe dyspnea (shortness of breath) and are at an increased risk regarding several different types of lung ... Studies have shown that in urban areas patients suffer mucus hypersecretion, lower levels of lung function, and more self- ... and dyspnea), reduced lung function (FEV1 and peak flow rate), and increased sputum production and purulence. The differences ...
The Food and Drug Administration approved the vagus nerve stimulator in 1997 as a way to control seizures in some patients with ... Engleman EG, Lankton J, Lankton B (December 1971). "Granulated sugar as treatment for hiccups in conscious patients". The New ... "Retrospective analysis of hiccups in patients at a community hospital from 1995-2000". J Natl Med Assoc. 94 (6): 480-3. PMC ...
Marc H. Lavietes, "The Interpretation of Dyspnea in the Patient with Asthma," Pulmonary Medicine, vol. 2015, Article ID 869673 ... The Interpretation of Dyspnea in the Patient with Asthma. Marc H. Lavietes ...
Dyspnea Caused by Atlantoaxial Subluxation in a Patient with Rheumatoid Arthritis. Hsin-Yi Lin,1 Chien-Chih Chen,2 Yi-Kung Lee, ... Hsin-Yi Lin, Chien-Chih Chen, Yi-Kung Lee, and Yung-Cheng Su, "Dyspnea Caused by Atlantoaxial Subluxation in a Patient with ...
Sex differences in exertional dyspnea in patients with mild COPD: physiological mechanisms.. Guenette JA1, Jensen D, Webb KA, ... The purpose of this study was to evaluate the physiological basis for sex-differences in exercise-induced dyspnea in patients ... Women with COPD had significantly greater dyspnea than men at 60 and 80 W. At 80 W, dyspnea ratings were 5.7±2.3 and 3.3±2.5 ... There were no sex differences in dyspnea in the control group at any work-rate or ventilation (V(E)). ...
Breakthrough Dyspnea Fentanyl Study in Cancer Patients. The safety and scientific validity of this study is the responsibility ... Ambulatory patients with breakthrough dyspnea performed a baseline 6 minute walk test (6MWT), and then received either ... Dyspnea. Exercise-induced breakthrough dyspnea. Shortness of breath. Fentanyl. Sublimaze. Placebo. Normal saline. NS. ... Breakthrough dyspnea, defined in this study as dyspnea on exertion with an average intensity level ,=3/10 on the numeric rating ...
Although dyspnea is often considered a single sensation, alternatively it may encompass multiple sensations that are not well ... Dyspnea frequently accompanies a variety of cardiopulmonary abnormalities. ... Distinguishable types of dyspnea in patients with shortness of breath Am Rev Respir Dis. 1990 Nov;142(5):1009-14. doi: 10.1164/ ... Patients were asked to choose descriptions of their sensation(s) of breathlessness from a dyspnea questionnaire listing 19 ...
... on dyspnea uncontrollable by standard therapy in patients with terminal cancer. Dyspnea was evaluated using the Cancer Dyspnea ... Effect of nebulized furosemide in terminally ill cancer patients with dyspnea.. Kohara H1, Ueoka H, Aoe K, Maeda T, Takeyama H ... In 12 of 15 patients (80%), total dyspnea scores by CDS improved significantly after inhalation of furosemide (P = 0.007), ... Inhalation of nebulized furosemide appears to be effective against dyspnea in terminally ill cancer patients. ...
Respiratory muscle function and dyspnea in patients with chronic congestive heart failure.. D M Mancini, D Henson, J LaManca, S ... BACKGROUND Patients with heart failure (HF) frequently experience exertional dyspnea. Using near-infrared spectroscopy, we have ... Respiratory muscle function and dyspnea in patients with chronic congestive heart failure. ... Respiratory muscle function and dyspnea in patients with chronic congestive heart failure. ...
The dyspnoea was exacerbated by upright posture and improved with recumbency. The hypoxaemia could not be corrected with ... He presented to the emergency department with 2 days of progressive dyspnoea. Clinical manifestations included respiratory ...
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On the basis of the patients unexplained progressive dyspnoea, impaired gas transfer and CT findings, an open VATS-assisted ... There was no history of haemoptysis and the patient was a lifelong non-smoker. On examination, the patient was afebrile, ... Dyspnea secondary to pulmonary hematopoiesis as presenting symptom of myelofibrosis with myeloid metaplasia. Am J Hematol 2006; ... A 41-year-old with idiopathic myelofibrosis was referred to the chest clinic with a 1-month history of progressive dyspnoea and ...
Dyspnea has been defined as an uncomfortable awareness of breathing [1]. It occurs in approximately 29% to 74% of patients with ... Subcutaneous Morphine for Dyspnea in Cancer Patients Eduardo Bruera, MD; Tara MacEachern, RN, BScN; Carla Ripamonti, MD; John ... Palliative oxygen and room air did not differ for relief of breathlessness in patients with refractory dyspnea Annals of ... Palliative oxygen and room air did not differ for relief of breathlessness in patients with refractory dyspnea Annals of ...
Although patients with MRC dyspnoea grade 2 referred for PR have better exercise capacity and fewer symptoms of dyspnoea, ... The results were analysed for 126 patients with MRC grade 2 dyspnoea and 316 with MRC grades 3/4 dyspnoea who completed PR ( ... All patients with MRC grade 2 dyspnoea referred to the Lambeth & Southwark Community Pulmonary Rehabilitation Team between the ... Changes in outcomes between patients with MRC grade 2 and those with MRC grades 3 or 4 dyspnoea before and after PR were ...
This according to a study that included consecutive patients with unexplained dyspnea referred for invasive hemodynamic ... causes of dyspnea and can assist in determination of the need for further diagnostic testing in the evaluation of patients with ... Diagnosis of HFpEF (case) or non-cardiac dyspnea (control) was determined by invasive hemodynamic exercise testing. ... Estimating HFpEF in Patients with Unexplained Dyspnea. Circulation; ePub 2018 May 23; Reddy, et al. Publish date:. June 4, 2018 ...
Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD.. The safety and scientific ... When patients return home left on their own again, dyspnea anxiety is likely to reappear and motivation may not be enough. ... As proposed by Morélot-Panzini et al in 2016, for filling it up, patient will be asked to focus on his worst dyspnea experience ... As proposed by Morélot-Panzini et al in 2016, for filling it up, patient will be asked to focus on his worst dyspnea experience ...
Dyspnea is a common complaint in obese patients. The mechanisms behind this dyspnea and the effects of weight loss on dyspnea ... Baseline dyspnea was assessed using the baseline dyspnea index.The effect of weight loss on dyspnea was assessed using the ... Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss. The safety and scientific ... Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss. ...
Chronic Dyspnea in a Patient With Stable CHD. Feb 28, 2018 , jocelyne benatar, MB ChB Share via: ... In this patient, the most common causes of dyspnea (atypical angina, arrhythmias, heart failure, asthma, COPD, anemia, thyroid ... YOU ARE HERE: Home , Education and Meetings , Chronic Dyspnea in a Patient With Stable CHD ... A cardiopulmonary test could be useful to assess the workload that the patient can achieve, the degree of dyspnea experienced, ...
Dyspnea, the subjective sensation of uncomfortable breathing, is often treated by titration of an opioid to relieve the symptom ... Patients with low performance status are not candidates for surgical treatment of bowel obstruction. Cramping abdominal pain ... prophylaxis with a gastrointestinal motility stimulant laxative and a stool softener is appropriate in terminally ill patients ... patients who are approaching the end of life commonly have other symptoms. Unless contraindicated, ...
... but it can be managed to keep patients comfortable, alleviate anxiety, and honor the patients wishes. ... Dyspnea is a distressing symptom in the dying process, ... In contrast, for patients with dyspnea in the setting of a ... Dyspnea is one of the most distressing symptoms experienced by dying patients, and it is a common reason for such patients to ... Dyspnea is one of the most common symptoms that patients encounter at the end of life. In patients with terminal cancer, 70% to ...
Qualitative aspects of exertional dyspnea in ILD patients before and after oxygen supplementation. Josuel Ora, Angelo Coppola, ... Conclusion: In ILD patients, O2th increases the 6MWD. It reduces the dyspnea overall perception and the anxiety component of ... Qualitative aspects of exertional dyspnea in ILD patients before and after oxygen supplementation ... Qualitative aspects of exertional dyspnea in ILD patients before and after oxygen supplementation ...
The purpose of this study was to demonstrate that clinical ratings of dyspnea and physiologic function are separate dimensions ... A factor analysis of dyspnea ratings, respiratory muscle strength, and lung function in patients with chronic obstructive ... by severity of dyspnea ratings, or by severity of airflow obstruction. We conclude that dyspnea ratings, maximal respiratory ... The purpose of this study was to demonstrate that clinical ratings of dyspnea and physiologic function are separate dimensions ...
... a consensus statement to influence clinical practice and provide suggestions regarding the management of dyspnea in patients ... One study found that many patients who died of chronic obstructive pulmonary disease had dyspnea, with serious dyspnea more ... Patients have not received consistent or effective treatment for dyspnea; therefore, the American College of Chest Physicians ( ... The ACCP determined that supplemental oxygen can provide relief for patients with dyspnea who are hypoxemic at rest or during ...
... with a face-to-face dyspnea self-management program (fDSMP) on the primary outcome of dyspnea with ADL in patients with ... Dyspnea with ADL was measured with the CRQ-Dyspnea subscale, which has been validated in previous studies [33,34]. Participants ... Randomized Controlled Trial of an Internet-Based Versus Face-to-Face Dyspnea Self-Management Program for Patients With Chronic ... Is Internet-based support for dyspnea self-management in patients with chronic obstructive pulmonary disease possible? Results ...
Palliative oxygen and room air did not differ for relief of breathlessness in patients with refractory dyspnea Annals of ... A model combining clinical assessment and NT-proBNP level accurately predicted heart failure in ED patients with dyspnea Annals ... Meta-analysis: Effect of B-Type Natriuretic Peptide Testing on Clinical Outcomes in Patients With Acute Dyspnea in the ... B-Type Natriuretic Peptide Testing, Clinical Outcomes, and Health Services Use in Emergency Department Patients With Dyspnea: A ...
... dyspnea, and death rattle. Nearly all these patients are at risk for the development of delirium. Patients who are alert may ... Caring for Patients at the End of Life in the Intensive Care Unit Managing Pain, Dyspnea, Anxiety, Delirium, and Death Rattle. ... Caring for Patients at the End of Life in the Intensive Care Unit Managing Pain, Dyspnea, Anxiety, Delirium, and Death Rattle. ... Pain, dyspnea, and anxiety should be routinely assessed by patient self-report when possible. Routine behavioral screening for ...
R.J. Bernardo, H. Jaliawala, H. Bhardwaj, H. Youness (Oklahoma City, USA). A 58-year-old Caucasian patient with dyspnea on ... A 58-year-old Caucasian patient with dyspnea on exertion. R.J. Bernardo, H. Jaliawala, H. Bhardwaj, H. Youness (Oklahoma City, ...
Evaluation of the patient with chronic dyspnea: Clinical application of pathophysiologic principles. Prim Care Case Reviews. ... Evaluation of the patient with chronic dyspnea: Clinical application of pathophysiologic principles ... Evaluation of the patient with chronic dyspnea: Clinical application of pathophysiologic principles. ...
Background Patients with CTD often complain of exertion dyspnea, due to lung diseases, heart diseases, musculoskeletal ... Objectives We performed CPET in patients who complained of exertion dyspnea and tried to detect early PV. ... PAH with SSc in patients with functional class? dyspnea; mild symptoms but severe outcome. Rheumatology 2010;49:940-4. ... SAT0370 Evaluations of exertion dyspnea in patients with connective tissue disease (CTD) by CPET (cardiopulmonary exercise ...
A full diagnostic work-up for patients with pulmonary hypertension (PH) is vital. Classification and diagnosis of the ... This case study describes how a full work-up identified chronic thromboembolic PH (CTEPH) as the cause of dyspnoea in a 68-yr- ... The patient was eligible for pulmonary endarterectomy according to established criteria. Residual PH after surgery was ... Dyspnea / etiology*, radiography, surgery. Endarterectomy. Humans. Hypertension, Pulmonary / complications*, drug therapy, ...
Factor analysis of exercise capacity, dyspnoea ratings and lung function in patients with severe COPD. RE Wegner, RA Jorres, DK ... Factor analysis of exercise capacity, dyspnoea ratings and lung function in patients with severe COPD ... Factor analysis of exercise capacity, dyspnoea ratings and lung function in patients with severe COPD ... Factor analysis of exercise capacity, dyspnoea ratings and lung function in patients with severe COPD ...
... and the Dyspnea Case Standardized Patient (Appendix G).. Simulator: A patient-actor (standardized patient) with Ventriloscope ... In this scenario, dyspnea is used to describe a patient with disordered or inadequate breathing.15 A team brief of medical ... The dyspnea in a hospitalized patient scenario has equivalent outcomes to two other scenarios used in our workshop series, ... Dyspnea in a Hospitalized Patient: Using Simulation to Introduce Interprofessional Collaborative Practice Concepts Sharon ...
  • To investigate whether breathlessness experienced by patients represents more than one sensation, we studied 53 patients with one of the following seven conditions: pulmonary vascular disease, neuromuscular and chest wall disease, congestive heart failure, pregnancy, interstitial lung disease, asthma, and chronic obstructive pulmonary disease. (nih.gov)
  • Linear correlation analysis was performed between ratings of perceived dyspnea and parameters of pulmonary and diaphragmatic function. (ahajournals.org)
  • 2 Pleural-based tumours and paraspinal masses are the most common thoracic manifestations of EMH, 3 while pulmonary interstitial EMH is rare and usually occurs in patients with an antecedent haematologic disorder. (bmj.com)
  • Influence of Particulate Matter during Seasonal Smog on Quality of Life and Lung Function in Patients with Chronic Obstructive Pulmonary Disease. (annals.org)
  • The recent INTERCOM study emphasises the point that community-based rehabilitation is effective, even in patients with chronic obstructive pulmonary disease (COPD) with less advanced airflow obstruction. (bmj.com)
  • 1 However, COPD and pulmonary rehabilitation guidelines recommend offering pulmonary rehabilitation (PR) to patients who consider themselves functionally disabled (usually defined as MRC Dyspnoea Scale grades 3 or above). (bmj.com)
  • All patients with MRC grade 2 dyspnoea referred to the Lambeth & Southwark Community Pulmonary Rehabilitation Team between the years 2004-7 were included in the study. (bmj.com)
  • The purpose of the clinical study is to compare the effect of hypnosis intervention on the emotional dimension of the dyspnea during a pulmonary rehabilitation program to the pulmonary rehabilitation program alone. (clinicaltrials.gov)
  • While physical activity level is the best predictor of life expectancy for patients with chronic obstructive pulmonary disease (COPD), the majority of patients have physical activity levels well below guidelines. (clinicaltrials.gov)
  • The most effective treatment to reduce dyspnea is pulmonary rehabilitation. (clinicaltrials.gov)
  • Indeed, during a pulmonary rehabilitation stay, patients practice under health professionals' supervision and advices with regular feedback on their abilities. (clinicaltrials.gov)
  • The investigators hypothesize that hypnosis used in addition to a 4-week pulmonary rehabilitation program will maintain the benefits on the emotional dimension of dyspnea at 6 months in the experimental group compared to a control group. (clinicaltrials.gov)
  • The main objective is to evaluate the impact of a hypnosis intervention during a pulmonary rehabilitation program on the emotional dimension of dyspnea 6 months after patients return home (T2). (clinicaltrials.gov)
  • The investigators compared pulmonary function, exercise performance and dyspnea in 34 patients with abdominal obesity and metabolic syndrome (MS) against 34 age and sex-matched controls. (clinicaltrials.gov)
  • Pulmonary function, exercise performance and dyspnea results for normal weight controls were compared against the results for obese subjects. (clinicaltrials.gov)
  • The most common causes of chronic dyspnea in this age group are pulmonary and cardiac causes. (acc.org)
  • The purpose of this study was to demonstrate that clinical ratings of dyspnea and physiologic function are separate dimensions underlying the pathophysiology of chronic obstructive pulmonary disease (COPD). (nih.gov)
  • More than 90 percent of patients with advanced chronic obstructive pulmonary disease and more than 60 percent with advanced heart disease experience breathlessness. (aafp.org)
  • One study found that many patients who died of chronic obstructive pulmonary disease had dyspnea, with serious dyspnea more common than serious pain. (aafp.org)
  • Another study found that progressive muscle relaxation reduced dyspnea in patients with chronic obstructive pulmonary disease after each of four weekly sessions, but not at the end of the four-week period. (aafp.org)
  • People with chronic obstructive pulmonary disease (COPD) continue to experience dyspnea with activities of daily living (ADL) despite optimal medical management. (jmir.org)
  • Chronic thromboembolic pulmonary hypertension as a cause of dyspnoea in an older patient with a complex history. (biomedsearch.com)
  • A full diagnostic work-up for patients with pulmonary hypertension (PH) is vital. (biomedsearch.com)
  • This case study describes how a full work-up identified chronic thromboembolic PH (CTEPH) as the cause of dyspnoea in a 68-yr-old male with a history of pulmonary embolism and an original diagnosis of chronic obstructive pulmonary disease. (biomedsearch.com)
  • The patient was eligible for pulmonary endarterectomy according to established criteria. (biomedsearch.com)
  • In this study we aimed to determine the relationship between exercise capacity, clinical ratings of dyspnoea and lung function parameters in patients with severe chronic obstructive pulmonary disease (COPD) by means of the statistical method of factor analysis. (ersjournals.com)
  • A total of 105 active duty military patients with complaints of exertional dyspnea and 69 active duty military asymptomatic controls were evaluated at a pulmonary disease clinic at an Army tertiary care center. (eurekamag.com)
  • In this randomised, crossover trial, 22 patients with severe chronic obstructive pulmonary disease climbed six flights of stairs (108 steps) twice, under two test conditions: (1) energy conservation technique (ECT): participants were asked to rest for at least 5 seconds every three steps and (2) control condition: participants climbed the stairs at their own pace. (onmedica.com)
  • Dyspnea (difficulty breathing) is a cardinal symptom of chronic obstructive pulmonary disease (COPD). (thecamreport.com)
  • AIMS: To evaluate long-term safety and efficacy of ticagrelor monotherapy in patients undergoing percutaneous coronary interventions (PCIs) in relation to chronic obstructive pulmonary disease (COPD) at baseline and the occurrence of dyspnoea reported as adverse event (AE) that may lead to treatment non-adherence. (eur.nl)
  • Pulmonary embolism can be obvious or subtle and should be considered in patients taking exogenous estrogen and those with a history of cancer, recent immobilization, surgery, or leg swelling. (mhmedical.com)
  • Early and accurate diagnosis of AHF is particularly challenging in patients with a history of both cardiac and obstructive pulmonary disease. (acutecaretesting.org)
  • Whereas risk scores are widely used in other acute settings such as acute coronary syndrome ( 3,4 ) and acute pulmonary embolism ( 5 ), a risk score for short-term risk assessment in acute or recent onset dyspnea is not yet established. (onlinejacc.org)
  • Exercise tolerance and dyspnea in patients with chronic obstructive pulmonary disease]. (semanticscholar.org)
  • BACKGROUND/AIM Peripheral muscle weakness and nutritional disorders, firstly loss of body weight, are common findings in patients with chronic obstructive pulmonary disease (COPD). (semanticscholar.org)
  • A 64-yr-old male first presented in 2003 at a local chest hospital with exertional dyspnoea, following a pulmonary embolism in 2002 and a history of smoking. (ersjournals.com)
  • However, the diffusing capacity of the lung for carbon monoxide was reduced (59%), as is the case in ∼20% of patients with idiopathic pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension (CTEPH) [ 1 , 2 ]. (ersjournals.com)
  • The patient met the established criteria for pulmonary endarterectomy [ 4 ], including mean P pa ≥25 mmHg, ≥3 months of effective oral anticoagulation, evidence of surgically accessible thrombi, a beneficial relationship between pulmonary vascular resistance (PVR) and the anticipated thrombus mass, no comorbidities and no severe reduction in lung function. (ersjournals.com)
  • The most common causes of dyspnea include exacerbation of chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF). (viamedica.pl)
  • Transthoracic lung ultrasound assessment is a simple and easily accessible examination, enabling the early and explicit diagnostics of pulmonary oedema and its distinction from other, non-cardiac causes of dyspnea. (viamedica.pl)
  • Dyspnoea and decreased exercise tolerance are symptoms of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). (viamedica.pl)
  • If you have seen a local Pulmonary Physician and you still feel that the problem has not been solved, then we may be able to set up an appointment for you with specialists in dyspnea at the Beth Israel Deaconess Medical Center for an evaluation and second opinion consultation. (shortofbreath.org)
  • When we determine a patient's dyspnea is caused by a pulmonary disorder, we develop the patient's personalized treatment plan and manage his or her follow-up care. (massgeneral.org)
  • Dyspnea, however, sometimes affects not only the pulmonary system, but also the cardiovascular and/or neuromuscular systems. (massgeneral.org)
  • A sudden onset strongly suggests pneumothorax (especially in a young, otherwise healthy patient) or pulmonary embolism (particularly in an immobilized patient). (patientcareonline.com)
  • Pulmonary embolism is suggested by a sudden exacerbation of dyspnea, increased ventilation, and a drop in PaCO2. (patientcareonline.com)
  • Consequently, dyspnea can result from intense reflex stimulation of breathing as a result of pulmonary inflammation (eg, pneumonia), an acute pulmonary vascular abnormality (eg, pulmonary embolism), engorgement (eg, pulmonary edema), respiratory mechanical defects (eg, airways obstruction), or a diaphragmatic defect. (patientcareonline.com)
  • Acute dyspnea may be associated with a pulmonary and/or cardiac abnormality or disease. (patientcareonline.com)
  • Sometimes pinpointed by the patient almost to the breath, a sudden onset strongly indicates either pneumothorax or pulmonary embolism. (patientcareonline.com)
  • Pneumothorax is more likely in a healthy young person with no underlying illness, whereas pulmonary embolism must be considered in a patient with risk factors for deep venous thrombosis, such as prolonged bed rest. (patientcareonline.com)
  • Among immunocompromised patients, however, especially those who are HIV-positive, increasing shortness of breath is often the sole presenting symptom of pulmonary infection. (patientcareonline.com)
  • Within minutes, and with the additive information from the combined cardiac, subcostal IVC, and lung ultrasound imaging, the patient was diagnosed with acute on chronic congestive heart failure and flash pulmonary edema as the cause of his respiratory distress and hypoxia. (com.pk)
  • As the patient was being prepped for intubation, X-ray imaging was obtained confirming the diagnosis of pulmonary edema. (com.pk)
  • The Dyspnea Center is a collaboration between UH Harrington Heart & Vascular Institute's Evaluation & Prevention Center and the Division of Pulmonary, Critical Care and Sleep Medicine at University Hospitals Cleveland Medical Center. (uhhospitals.org)
  • Many patients with breathlessness have both cardiovascular and pulmonary diseases that require treatment, so the Dyspnea Center provides expanded diagnostic testing to measure both heart and lung function in patients. (uhhospitals.org)
  • In this descriptive, cross-sectional study, we included prospectively all patients admitted with decompensated HF and chronic obstructive pulmonary disease (COPD)/pulmonary fibrosis during 4 months. (biomedcentral.com)
  • A total of 258 patients were included: 190 (73.6%) with HF and 68 (26.4%) with RD (62 COPD and 6 pulmonary fibrosis). (biomedcentral.com)
  • The main aim of this study is to evaluate the intensity of dyspnoea in patients hospitalised for HF and RD (chronic obstructive pulmonary disease [COPD] and pulmonary fibrosis) at admission and discharge, and its relation with quality of life. (biomedcentral.com)
  • In fact, patients older than 65 years bear a disproportionate burden of cancer as well as increased prevalence of medical problems such as chronic obstructive pulmonary disease, heart disease, diabetes, and hypertension. (cancer.gov)
  • 3 ] Cancer patients are often also at higher risk for pulmonary infections. (cancer.gov)
  • In patients with acute shortness of breath, the diagnosis of the cause is often difficult, particularly the differentiation between cardiac and pulmonary disease. (soheb.com)
  • The presence of hepatojugular reflux on physical examination is known to relate to invasive measures of central venous and pulmonary wedge pressure*' in selected patients. (soheb.com)
  • In addition, the response of the blood pressure during and after the Valsalva maneuver is classically described as relating to ventricular function, and has been shown to correlate well with left ventricular ejection fraction in patients with chronic obstructive pulmonary disease. (soheb.com)
  • Opioid therapy for refractory dyspnea in patients with advanced chronic obstructive pulmonary disease: patients' experiences and outcomes. (semanticscholar.org)
  • Chronic phosphodiesterase-5 inhibition with Sildenafil has been shown to improve peak oxygen consumption (VO2), ventilatory efficiency (VE/VCO2 slope) and pulmonary artery pressure (PAP) in patients with heart failure (HF). (unimi.it)
  • The impact of Sildenafil on dyspnea on exertion (DOE) or the relationship between changes in the exercise response and pulmonary hemodynamics following use of this pharmacologic agent are unknown. (unimi.it)
  • Improvement in ventilatory efficiency and dyspnea on exertion are related to reduced pulmonary pressure in heart failure patients undergoing chronic phosphodiesterase-5 inhibition / M. Guazzi, J. Myers, M.A. Peberdy, D. Bensimhon, P. Chase, S. Pinkstaff, R. Arena. (unimi.it)
  • 10 By contrast, the consensus summary of the Global Initiative on Chronic Obstructive Lung Disease (GOLD) of the National Heart, Lung, and Blood Institute of the US National Institutes of Health and the World Health Organization states that opioids are contraindicated in the management of dyspnoea in chronic obstructive pulmonary disease. (bmj.com)
  • The cause of acute dyspnea in chronic obstructive pulmonary disease is challenging. (comu.edu.tr)
  • Chest pain may be a neglected symptom of idiopathic pulmonary fibrosis (IPF), finds a Finnish study that also suggests using the modified Medical Research Council (mMRC) dyspnea ( shortness of breath ) scale to identify IPF patients needing palliative care. (pulmonaryfibrosisnews.com)
  • Dyspnea is a common complaint and in 70 to 90% the origin is pulmonary or cardiovascular. (ijic.org)
  • Variability of breathlessness measurement in patients with chronic obstructive pulmonary disease. (naver.com)
  • Psychologic and physiologic factors related to dyspnea in subjects with chronic obstructive pulmonary disease. (naver.com)
  • Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. (naver.com)
  • Dyspnea in obese individuals with chronic obstructive pulmonary disease COPD can be evaluated reliably by cycle ergometry as well as a treadmill test, researchers have found. (dontforgettobreathe.org.nz)
  • Pulmonary arteriovenous malformation's (PAVMs) are rare pulmonary vascular anomalies, occurring at increased frequency in patients with hereditary hemorrhagic telengactasia (HHT). (ispub.com)
  • ABGA parameters were neither useful to distinguish between patients with pulmonary disorders and other causes of dyspnea nor to identify specific disorders responsible for dyspnea. (unibas.ch)
  • pH at presentation was an independent predictor of 12-month mortality in multivariable Cox proportional hazard analysis both for patients with pulmonary (P = 0.043) and non-pulmonary disorders (P = 0.038). (unibas.ch)
  • The H 2 FPEF score enables discrimination of heart failure with preserved ejection fraction (HFpEF) from non-cardiac causes of dyspnea and can assist in determination of the need for further diagnostic testing in the evaluation of patients with unexplained exertional dyspnea. (mdedge.com)
  • Heart disease, lung disease, and anemia are the most common causes of dyspnea. (mhmedical.com)
  • This review outlines the current knowledge on the subject of transthoracic lung ultrasound (TLUS), particularly in respect of its clinical usefulness in distinction of causes of dyspnea exacerbation. (viamedica.pl)
  • In primary care it is often difficult to distinguish between the different causes of dyspnea. (ijic.org)
  • There are many potential causes of dyspnea in the patient with cancer. (fullcontentrss.com)
  • The goal of this clinical research study is to learn if fentanyl given under the skin can reduce shortness of breath in cancer patients. (clinicaltrials.gov)
  • It is believed to help patients with their shortness of breath as well. (clinicaltrials.gov)
  • The intensity of dyspnea at 0, 1, 2, 3, 4, 5 and 6 minute of each walk test were assessed using a validated numeric rating scale (NRS) ranging from 0 ('no shortness of breath') to 10 ('worst possible shortness of breath') and every 5 minutes during the rest period. (clinicaltrials.gov)
  • The dyspnea is not getting any worse over time, but he is worried that his shortness of breath means that he has something wrong and is too worried to exercise. (acc.org)
  • Background: This study aimed to determine epidemiology and outcome for patients presenting to emergency departments (ED) with shortness of breath who were transported by ambulance. (edu.au)
  • Discussion: Patients transported by ambulance with shortness of breath make up a significant proportion of ambulance caseload and have high comorbidity and high hospital admission rate. (edu.au)
  • Conclusion: This study shows that patients transported to hospital by ambulance with shortness of breath are a complex and seriously ill group with a broad range of diagnoses. (edu.au)
  • The Massachusetts General Hospital Dyspnea Clinic is staffed by world-class specialists who evaluate and treat patients with unexplained dyspnea (shortness of breath), including the most complicated cases. (massgeneral.org)
  • Unexplained dyspnea, also known as shortness of breath, affects people of all ages and lifestyles while at rest and/or during exercise. (massgeneral.org)
  • You may easily be misled about the severity of the underlying illness if, for example, an extremely stoic patient complains only of mild shortness of breath. (patientcareonline.com)
  • In this Lumify case study and summary video, Dr. Sara Nikravan discusses how she used her Philips Lumify handheld ultrasound system to guide the diagnosis and treatment of a patient experiencing shortness of breath. (com.pk)
  • Two days later, the patient began to have a fever, worsening shortness of breath with increased oxygen requirements, and inability to wean ionotropic and vasopressor support further. (com.pk)
  • For patients experiencing unexplained shortness of breath, or dyspnea, the specialists at University Hospitals Harrington Heart & Vascular Institute offer advanced testing capabilities to help diagnose the underlying condition or cause of the breathlessness. (uhhospitals.org)
  • We analyzed patients (n=452) included in the BNP for Acute Shortness of Breath Evaluation (BASEL) study. (unibas.ch)
  • Forty-six percent of the patients had some shortness of breath. (elsevier.com)
  • To determine the value of these clinical maneuvers in patients with acute dyspnea, we studied patients presenting to the emergency room with the chief complaint of shortness of breath. (soheb.com)
  • Patients with moderate shortness of breath (mMRC ≥2) showed a decrease in all areas of HRQOL, particularly in physical function, compared to the general population in Finland. (pulmonaryfibrosisnews.com)
  • Dyspnea, the clinical term for shortness of breath, is the primary symptom and an important outcome measure in evaluations of patients with lung disease. (naver.com)
  • In this study, we evaluated 6 measures of dyspnea for reliability and validity: (a) Baseline Dyspnea Index (BDI) and Transition Dyspnea Index, (b) UCSD Shortness of Breath Questionnaire (SOBQ), (c) American Thoracic Society Dyspnea Scale, (d) Oxygen Cost Diagram, (e) Visual Analog Scale, and (f) Borg Scale. (naver.com)
  • Any of these conditions may lead to the shortness of breath or dyspnea. (orlandomedicalnews.com)
  • After a year and a half of working to implement these techniques, the Cornerstone Hospice team realized one metric was the most indicative of a patient's success in self-managing dyspnea: Whether the patient and caregiver had the confidence to be able to self-manage an episode of shortness of breath. (orlandomedicalnews.com)
  • The theophylline dose of a patient admitted for COPD exacerbation and pneumonia is doubled, and he develops atrial flutter with a rapid ventricular response, chest pain, and increased shortness of breath. (ahrq.gov)
  • Sex differences in exertional dyspnea in patients with mild COPD: physiological mechanisms. (nih.gov)
  • BACKGROUND Patients with heart failure (HF) frequently experience exertional dyspnea. (ahajournals.org)
  • Minimal information currently exists on how clinicians should approach the evaluation of the young patient with exertional dyspnea. (eurekamag.com)
  • The objective of this study was to determine the frequency of specific diseases and the most useful tests to establish the diagnosis in an active duty military population presenting with exertional dyspnea. (eurekamag.com)
  • The 56-year-old female patient, a former smoker, was referred to our outpatient clinic for exertional dyspnea and persistent wheezing. (biomedcentral.com)
  • The patient complained of wheezing, present both during inspiration and expiration, and exertional dyspnea while climbing stairs, without other respiratory or systemic symptoms over the past 3 months. (biomedcentral.com)
  • The patient claimed that, t wo month ago, he started to complain of progressive exertional dyspnea, cough and expectoration of yellowish (sometimes blood tinged) sputum which increase at night and on lying down. (kasralainy.edu.eg)
  • He recently had some worse exertional dyspnea and was taking extra furosemide at home. (surveymonkey.com)
  • Controlled single-dose trials have suggested that opioids are effective in the management of dyspnea associated with chronic obstructive lung disease [4] . (annals.org)
  • therefore, the American College of Chest Physicians (ACCP) wrote a consensus statement to influence clinical practice and provide suggestions regarding the management of dyspnea in patients with advanced lung or heart disease. (aafp.org)
  • PDF] American College of Chest Physicians consensus statement on the management of dyspnea in patients with advanced lung or heart disease. (semanticscholar.org)
  • Hospitalist attitudes toward the assessment and management of dyspnea in patients with acute cardiopulmonary diseases. (semanticscholar.org)
  • An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea. (semanticscholar.org)
  • An official American Thoracic Society workshop report: assessment and palliative management of dyspnea crisis. (semanticscholar.org)
  • Inflammatory biomarkers predicting prognosis in patients with acute dyspnea. (lu.se)
  • The objective was to identify inflammatory biomarkers that predict risk of 90-day mortality in patients with acute dyspnea. (lu.se)
  • This short review aims to put the diagnostic options provided by state-of-the-art POCT technology into perspective with the clinical challenges faced by physicians treating patients presenting with acute dyspnea. (acutecaretesting.org)
  • Acute dyspnea is the key symptom of about 5-10 % of patients presenting to the emergency department (ED) [1-7]. (acutecaretesting.org)
  • In contrast to common thinking, the mortality of patients presenting with acute dyspnea is even higher than that of patients presenting with acute chest pain. (acutecaretesting.org)
  • First, ensuring that AHF is the cause of acute dyspnea. (acutecaretesting.org)
  • Fig. 2: Biomarkers complement clinical assessment and other diagnostic tools in the assessment of patients with suspected acute heart failure. (acutecaretesting.org)
  • These data justify the liberal use of NPs in all patients presenting with acute dyspnea. (acutecaretesting.org)
  • Natriuretic peptide levels should be interpreted as a quantitative variable with higher levels indicating a higher likelihood for AHF being the main cause of acute dyspnea. (acutecaretesting.org)
  • Acute onset or progressive increase in dyspnea can indicate both harmless as well as highly lethal conditions ( 1,2 ). (onlinejacc.org)
  • A risk score for long-term mortality in acute dyspnea has been developed ( 6 ) that takes into account N-terminal pro-B-type natriuretic peptide (NT-proBNP): 1 of the most studied and clinically implemented biomarkers in acute dyspnea ( 7 ). (onlinejacc.org)
  • However, many more biomarkers have emerged over the last years and they are suggested to provide additional or superior prognostic information in patients with dyspnea and acute heart failure ( 8-13 ). (onlinejacc.org)
  • ABSTRACT: The rate at which acute dyspnea develops can point to its cause. (patientcareonline.com)
  • The survival of a patient with acute dyspnea may depend on your ability to identify and promptly treat the underlying cause. (patientcareonline.com)
  • Asthma or acute exacerbation of chronic bronchitis as the cause of increasing dyspnea can usually be diagnosed by the patient's history and the characteristic wheezing that accompanies the dyspnea. (patientcareonline.com)
  • The patient was extubated to high-flow oxygen by nasal cannula after successfully passing a spontaneous breathing trial, although, he had failed extubation one week prior secondary to acute dyspnea and hypoxia. (com.pk)
  • We evaluated the prognostic role of sST2 for patients presenting to the emergency department with acute dyspnea, with a focus on those with preserved left ventricular ejection fraction (LVEF ≥50%), as risk stratification is often most complex in this subgroup. (elsevier.com)
  • CONCLUSIONS: sST2 is a strong predictor of mortality in patients presenting with acute dyspnea, particularly those with preserved LVEF, and may be useful for triage and risk stratification of this challenging group. (elsevier.com)
  • This entry was posted in Acute Dyspnea and tagged Congestive heart failure , Dyspnea . (soheb.com)
  • In this study, we aimed to perform a randomized, standard therapy controlled evaluation of the diagnostic accuracy and temporal impact of a standardized ultrasound strategy, versus standard care, in patients presenting to the ED with acute dyspnea. (bvsalud.org)
  • A standardized ultrasound approach is equally accurate, but enables faster ED diagnosis of acute dyspnea than standard care. (bvsalud.org)
  • Is there a clinically meaningful difference in patient reported dyspnea in acute heart failure? (elsevier.com)
  • Background Dyspnea is the most common presenting symptom in patients with acute heart failure (AHF), but is difficult to quantify as a research measure. (elsevier.com)
  • Acute Progressive Dyspnea in a Patient W. (comu.edu.tr)
  • In conclusions, lung cancer can be a rare cause of acute dyspnea. (comu.edu.tr)
  • The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. (bmj.com)
  • Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. (bmj.com)
  • Chronic alcohol abuse is associated with an increased incidence of acute respiratory distress syndrome and severity of multiple organ dysfunction in patients with septic shock. (bmj.com)
  • Early markers of acute respiratory distress syndrome development in severe trauma patients. (bmj.com)
  • The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown. (unibas.ch)
  • We performed a post-hoc analysis of two different prospective studies to investigate the diagnostic and prognostic value of ABGA parameters in patients presenting to the ED with acute dyspnea. (unibas.ch)
  • ABGA parameters provide limited diagnostic value in patients with acute dyspnea, but pH is an independent predictor of 12 months mortality. (unibas.ch)
  • A 72-year-old man has ongoing dyspnea on exertion since his non-ST-segment elevation myocardial infarction (NSTEMI) 1 year ago. (acc.org)
  • Background Patients with CTD often complain of exertion dyspnea, due to lung diseases, heart diseases, musculoskeletal disorders and/or APAH. (bmj.com)
  • 2-3 We evaluated exertion dyspnea of unknown to find out early APAH with CPET. (bmj.com)
  • Objectives We performed CPET in patients who complained of exertion dyspnea and tried to detect early PV. (bmj.com)
  • 8 cases, with decreased peak VO2 but normal VE/VCO 2, were regarded that muscle weakness mainly induced exertion dyspnea, and advised exercise. (bmj.com)
  • Functional impact will be measured on the 4-point categorical Modified Medical Research Council of Great Britain (MRC) dyspnea scale and the Dyspnea Exertion Scale (DES). (isrctn.com)
  • One reason is our staff, which includes a board-certified pulmonologist and exercise physiologist who has specialized in dyspnea during exertion for over two decades. (massgeneral.org)
  • The study confirms that 6MWT distance and dyspnea on exertion are key elements in prognostic evaluation in COPD, while the value of exercise oxygen desaturation is less clear. (rcjournal.com)
  • The patient did have dyspnea on exertion, but was able to get into a chair during frequent visits from his niece and even his cat, who was allowed to visit him on the palliative care inpatient unit. (clinmedjournals.org)
  • Main outcome measures Dyspnoea in the morning and evening as shown on a 100 mm visual analogue scale, quality of sleep, wellbeing, performance on physical exertion, and side effects as measured at the end of the four day treatment period. (bmj.com)
  • Respiratory muscle function and dyspnea in patients with chronic congestive heart failure. (ahajournals.org)
  • Using near-infrared spectroscopy, we have previously demonstrated accessory respiratory muscle deoxygenation during exercise in these patients by monitoring changes in light absorption at 760-800 nm. (ahajournals.org)
  • Pdi, time in inspiration (Ti), time per breath (TTOT), respiratory gases, ratings of perceived dyspnea and fatigue, and 760-800 nm near-infrared spectroscopy absorbency changes of the serratus anterior muscle were measured throughout exercise. (ahajournals.org)
  • Thus, respiratory muscle strength, work, and oxygenation were significantly correlated with the degree of dyspnea. (ahajournals.org)
  • CONCLUSIONS We conclude that low-frequency diaphragmatic muscle fatigue does not occur despite accessory respiratory muscle deoxygenation during exercise in patients with HF. (ahajournals.org)
  • The sensation of dyspnea appears closely related to respiratory muscle function. (ahajournals.org)
  • Outcome measures were the incremental shuttle walk (ISW), the Chronic Respiratory Disease Questionnaire Dyspnoea score (CRQ-D) and the Hospital Anxiety and Depression Scale (HAD-Anxiety and HAD-Depression). (bmj.com)
  • They are en route to your ED with a 55-year-old woman in respiratory distress. (ebmedicine.net)
  • Dyspnea is a multidimensional respiratory sensation characterized by distinct components: sensorial (intensity, quality) and affective (anxiety, fear). (ersjournals.com)
  • We conclude that dyspnea ratings, maximal respiratory pressures, and lung function are separate factors or quantities that independently characterize the condition of patients with COPD. (nih.gov)
  • The primary outcome of dyspnea with ADL was measured with the Chronic Respiratory Questionnaire. (jmir.org)
  • Four different tools were chosen to rate dyspnoea and quality of life: the Baseline Dyspnoea Index (BDI), the Oxygen Cost Diagram (OCD), a modified Medical Research Council (MRC) Scale, and the Chronic Respiratory Disease Questionnaire (CRQ). (ersjournals.com)
  • Using patient-reported symptoms of dyspnea for screening reduced respiratory function in patients with motor neuron diseases. (onmedica.com)
  • Poor monitoring of respiratory function may lead to late initiation of non-invasive ventilation (NIV) in patients with motor neuron diseases (MND). (onmedica.com)
  • We aimed to determine which patient-reported hypoventilation symptoms are best for screening reduced respiratory function in patients with MND, and compared them to the respiratory domain of the amyotrophic lateral sclerosis functional rating scale (ALSFRS-R).This prospective multi-center study included 100 patients with MND, who were able to perform a supine vital capacity test. (onmedica.com)
  • The diagnostic performances of these symptoms and the ALSFRS-R respiratory domain were determined from the receiver operating characteristic (ROC) curves, area under the curve (AUC), sensitivity, specificity, predictive values and accuracy.Dyspnea-related symptoms (dyspnea while eating/talking, while lying flat and during light activity) were combined into the MND Dyspnea Scale (MND-DS). (onmedica.com)
  • Sleep-quality symptoms, sleepiness/fatigue-related symptoms and the ALSFRS-R respiratory domain showed weak diagnostic performance.The diagnostic performance of the MND-DS was better than the respiratory domain of the ALSFRS-R for screening reduced respiratory function in patients with MND, and is, therefore, the preferred method for (remotely) monitoring respiratory function. (onmedica.com)
  • How different are COPD-specific patient reported outcomes, health status, dyspnoea and respiratory symptoms? (bmj.com)
  • 60 % were accounted for by patients with heart failure, lower respiratory tract infection or COPD, but there were a wide range of diagnoses. (edu.au)
  • The TDI was significantly associated with changes in forced vital capacity and appeared more sensitive to changes in dyspnea than the ALS functional rating scale-respiratory subscale (ALS-FRS R) and a visual analog scale of breathlessness. (elsevier.com)
  • Awareness of fixation error may avoid misdiagnosis in patients with respiratory disease and a complicated history at presentation. (biomedcentral.com)
  • It is characterized by respiratory symptoms such as dyspnea, cough, and wheezing, often increasing at night and with exercise. (biomedcentral.com)
  • The patient had no history of allergies or respiratory disease. (biomedcentral.com)
  • At our respiratory service the patient was eupneic at rest, with normal clinical parameters while breathing room air and well nourished (body mass index 25.0 kg/m 2 ). (biomedcentral.com)
  • Dyspnoea is a disabling symptom in patients admitted with heart failure (HF) and respiratory diseases (RD). The main aim of this study is to evaluate its intensity at admission and discharge and the relation with quality of life. (biomedcentral.com)
  • We performed a descriptive study of dyspnoea performed in Cardiology and Respiratory Medicine Departments using a cross-sectional design in order to assess the magnitude of the problem of dyspnea. (biomedcentral.com)
  • Hospital without dyspnoea" is a multidisciplinary initiative started in 2014 that aims to reduce the prevalence of dyspnoea in hospitalised patients in our centre with a multidisciplinary approach that includes the departments of Palliative Care, Cardiology, and Respiratory Medicine [ 11 ]. (biomedcentral.com)
  • The patient improved with regard to respiratory complaints and lung function. (biomedcentral.com)
  • Prospective use of descriptors of dyspnea to diagnose common respiratory diseases. (semanticscholar.org)
  • Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease. (naver.com)
  • Interrupted during a telephone handoff, an ED physician, despite limited information, must treat a patient in respiratory arrest. (ahrq.gov)
  • In a three-year period in Central Denmark Region, all patients hospitalized within 24 h after a 1-1-2 emergency call and who subsequently received either a PPU or a PUB (hereinafter combined and referred to as PPU/PUB) or a First Hour Quintet (FHQ: respiratory failure, stroke, trauma, cardiac chest pain, and cardiac arrest) diagnosis were investigated. (springer.com)
  • The appearance of high-flow therapy has opened new doors in the treatment of these patients, as it is a technique that relieves dyspnea in respiratory patients, achieves adequate levels of oxygenation in most patients and is very well tolerated. (internationalhighflownetwork.com)
  • The purpose of this study was to evaluate the physiological basis for sex-differences in exercise-induced dyspnea in patients with mild COPD. (nih.gov)
  • We compared operating lung volumes, breathing pattern and dyspnea during incremental cycling in 32 men (FEV(1)=86±10% predicted) and women (FEV(1)=86±12% predicted) with mild COPD and 32 age-matched controls. (nih.gov)
  • 2 3 We wished to test whether less breathless patients with COPD (ie, MRC Dyspnoea Scale grade 2) also benefit from PR. (bmj.com)
  • Patients with COPD with MRC dyspnoea grades 3 or 4 undertaking PR over the same time period acted as controls. (bmj.com)
  • Exercise-based interventions for COPD should not ignore less severe patients (either in terms of lung function or subjective dyspnoea). (bmj.com)
  • Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD. (clinicaltrials.gov)
  • Given the analogy between pain and dyspnea, hypnosis could therefore constitute a therapeutic solution as a complement to rehabilitation to durably reduce dyspnea anxiety in patients with COPD, and promote a better behavior at middle and long term. (clinicaltrials.gov)
  • Stopping the beta-blocker is not likely to have much effect because the patient has mild COPD with no reversibility with salbutamol. (acc.org)
  • We used principal-components factor analysis to confirm these dimensions using data collected prospectively in 86 symptomatic patients with COPD. (nih.gov)
  • The purpose of this randomized study was to test the efficacy of two 6-month dyspnea self-management programs, Internet-based (eDSMP) and face-to-face (fDSMP), on dyspnea with ADL in people living with COPD. (jmir.org)
  • Energy conservation technique improves dyspnoea when patients with severe COPD climb stairs: a randomised crossover study. (onmedica.com)
  • Impact of COPD and dyspnoea AE (as a time-dependent covariate) on clinical outcomes was evaluated up to 2 years. (eur.nl)
  • Overall, at 2 years dyspnoea was reported as an AE in 2101 patients, more frequently among COPD patients, irrespective of treatment allocation (27.2% in experimental arm vs. 14.5% in reference arm, P = 0.001). (eur.nl)
  • Despite higher incidence of dyspnoea in the experimental arm, in particular among COPD patients, the safety of the experimental treatment strategy appeared not to be affected. (eur.nl)
  • Anaemia is a risk factor for reduced functional capacity and dyspnoea in stable COPD. (viamedica.pl)
  • presented as means ± SD): 402 patients with exacerbation of COPD (COPD stage 3.5 ± 0.6) were examined. (viamedica.pl)
  • 104 COPD patients were studied. (rcjournal.com)
  • 1 The 6-min walk test (6MWT) is an easy to perform submaximal exercise test that reflects the functional exercise capacity in COPD patients, and the 6-min walk distance (6MWD) correlates strongly with mortality in this disease. (rcjournal.com)
  • 7 We hypothesized that 6MWT work might be a better predictor of mortality in COPD patients than distance walked. (rcjournal.com)
  • This review article highlights the immense morbidity experienced by COPD patients, emphasizes the need for palliative care in this population, and focuses on treatment of refractory dyspnea with opioids as highlighted in our case. (clinmedjournals.org)
  • abstract = "BACKGROUND: Soluble ST2 (sST2), an interleukin-1 receptor family member, is an emerging risk indicator for patients with cardiovascular disease. (elsevier.com)
  • Written informed consent was obtained from the patient for publication of this abstract and any accompanying images. (biomedcentral.com)
  • 3 This symptom occurs in 25 to 85 percent of terminally ill patients. (aafp.org)
  • The early involvement of palliative medicine specialists and/or hospice services for dying patients can facilitate optimal symptom management and transitions of care. (ebmedicine.net)
  • Although it is not known what causes dyspnea, physicians should provide treatment for this symptom. (aafp.org)
  • Behavioral observation tools to detect pain and dyspnea and proxy assessments guide symptom identification when the patient cannot provide a self-report. (aacn.org)
  • List 3 symptom assessment tools for dying patients. (aacn.org)
  • We developed a 14-item hypoventilation symptom questionnaire (HYSQ) based on guidelines, expert opinion and think-aloud interviews with patients. (onmedica.com)
  • Let's be clear on the symptom of dyspnea. (thecamreport.com)
  • In addition, dyspnea is a challenging symptom with more than 30 possible underlying diagnoses. (acutecaretesting.org)
  • Dyspnea is a non-specific symptom that requires fast diagnostics, accurate diagnosis and proper treatment. (viamedica.pl)
  • Methods: This was a planned sub-study of a prospective, interrupted time series cohort study conducted at three time points in 2014 and which included consecutive adult patients presenting to the ED with dyspnoea as a main symptom. (edu.au)
  • Dyspnea is a common symptom of certain cancers such as lung cancer and is also common in patients with numerous advanced cancers. (cancer.gov)
  • 3 ] Patients with advanced cancer experience this symptom more frequently and more intensely than do patients with limited disease. (cancer.gov)
  • The objectives of this study were to determine the prevalence of dyspnea in the general cancer population, the intensity of the symptom as perceived by the patient, and the patient characteristics associated with the presence of dyspnea. (elsevier.com)
  • For this reason, researchers in Finland recently aimed to investigate HRQOL and symptom burden among IPF patients listed in the FinnishIPF Registry. (pulmonaryfibrosisnews.com)
  • The team evaluated patients' quality of life through a self-rating mMRC breathlessness scale and the RAND 36-Item Health Survey (RAND-36), and the frequency and mean intensity of symptoms by a modified Edmonton Symptom Assessment Scale (ESAS). (pulmonaryfibrosisnews.com)
  • The team concluded that "mMRC not only reflects breathlessness in patients with IPF but indicates HRQOL and overall symptom burden. (pulmonaryfibrosisnews.com)
  • Background: Dyspnea is a common and debilitating symptom of advanced lung cancer, with approximately 50% of patients reporting marked breathlessness. (grantome.com)
  • Conclusions: Other than opioid medications, which offer little clinical benefit, data are lacking to support the efficacy of treatments for dyspnea, a highly impairing symptom in patients with advanced lung cancer. (grantome.com)
  • By training medical clinicians to administer the behavioral intervention in the oncology care setting, we hope to maximize broad dissemination and patient access to essential symptom management. (grantome.com)
  • Through this study, we seek to increase access to much needed symptom management for those diagnosed with advanced lung cancers and ideally improve patients? (grantome.com)
  • In patients with known or suspected coronary artery disease, dyspnea is a symptom requiring investigation. (elsevier.com)
  • The National Association of Social Workers states that a key role of the social worker in the hospice setting is to provide psychosocial education to patients and family caregivers about coping skills, hospice and palliative care philosophy and nonpharmacological symptom management strategies. (orlandomedicalnews.com)
  • Dyspnea is the most common presenting symptom. (bmj.com)
  • Two reviews of palliative care determined that short-term opioid therapy is effective for treating dyspnea at the end of life. (aafp.org)
  • Critically ill patients receiving palliative care at the end of life are at high risk for experiencing pain, dyspnea, and death rattle. (aacn.org)
  • One study found that 75 of 135 patients with advanced cancer reporting to an outpatient palliative care clinic were experiencing moderate-to-severe dyspnea. (cancer.gov)
  • Palliative and end-of-life care for patients with cardiopulmonary diseases: American College of Chest Physicians position statement. (semanticscholar.org)
  • The palliative care team started him on a low dose opioid, morphine 5 mg orally every four hours around the clock, for refractory dyspnea along with sennakot twice daily. (clinmedjournals.org)
  • Breathlessness is a source of distress for 50-70% of patients requiring palliative care. (bmj.com)
  • 8 - 10 In Australia, consensus guidelines from the Therapeutic Guidelines Group in Palliative Care conclude that opioids contribute to the management of refractory dyspnoea. (bmj.com)
  • They also wanted to create a simple identification method for patients needing palliative care, by studying the link between dyspnea score and HRQOL. (pulmonaryfibrosisnews.com)
  • It suggested that "in clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care. (pulmonaryfibrosisnews.com)
  • A unique protocol implemented throughout Cornerstone Hospice and Palliative Care's seven-county region has been successful in helping patients and their family members cope through episodes of dyspnea. (orlandomedicalnews.com)
  • Eight Spanish pain units, eight palliative care units, and one oncology department included 152 patients. (springer.com)
  • One of the problems that we face in daily clinical practice is the palliative treatment of dyspnea in cancer patients. (internationalhighflownetwork.com)
  • Clinical introduction A 60-year-old man had a long history of chronic hepatitis C. He presented to the emergency department with 2 days of progressive dyspnoea. (bmj.com)
  • Methods From June 13th in 2015 to October 28th in 2016, we performed CPET and evaluate their clinical state in 28 patients, 17-80 years 2 males/26 females, 5 mixed connective tissue disease (MCTD), 15 SSc, 3 SLE, 2 Sjögren's syndrome, 3 dermatomyositis. (bmj.com)
  • This first step relies on clinical judgment to integrate patient history, physical examination, investigations including chest x-ray, the 12-lead ECG, as well as elevated levels of natriuretic peptides [1-5]. (acutecaretesting.org)
  • The MARKED-risk score that incorporates hs-cTnT, hs-CRP, and Cys-C along with clinical risk factors accurately identifies patients with very low, intermediate, and high risk. (onlinejacc.org)
  • 6MWT was performed after clinical improvement of the patient. (viamedica.pl)
  • At Mass General, the brightest minds in medicine collaborate on behalf of our patients to bridge innovation science with state-of-the-art clinical medicine. (massgeneral.org)
  • In this paper we describe the clinical investigations and interventions that eventually confirmed a diagnosis of asthma complicated by an idiopathic tracheal stenosis and led to effective treatment of the patient. (biomedcentral.com)
  • Due to worsening of the symptoms the patient presented to the Emergency Department, where clinical parameters were stable (oxygen saturation [SpO 2 ] of 98%) and a chest X-ray showed no infiltrates, nor pleural effusion. (biomedcentral.com)
  • If no cause is found on clinical examination the term unexplained dyspnea is applied. (scitechnol.com)
  • Due to these reasons dyspnoea has been recently recommended as a main endpoint of clinical trials [ 4 ]. (biomedcentral.com)
  • However, there have been reports indicating that various maneuvers performed during the physical examination of chronically ill patients may facilitate the clinical diagnosis of congestive heart failure. (soheb.com)
  • These diagnoses were then compared and related to the patients' response to the clinical maneuvers. (soheb.com)
  • Evaluation of clinical methods for rating dyspnea. (semanticscholar.org)
  • In clinical studies, approximately one out of three patients achieved a complete response or better on the Kyprolis in combination with lenalidomide and dexamethasone arm, which is three times more frequent than in the lenalidomide and dexamethasone arm,' said Prof. Meletios A. Dimopoulos , M.D., Department of Clinical Therapeutics, National and Kapodistrian University of Athens , School of Medicine. (prnewswire.com)
  • Sufficient studies have not been performed describing routine clinical practice in this type of patients, and this limitation prevents adequate evaluation of the added value of new treatments and their impact on costs. (springer.com)
  • To resolve this limitation, more information about real-life clinical practice for the management of patients with BTP, and their results in terms of quality of life and costs are needed. (springer.com)
  • Recently, Hui et al have published a randomized clinical trial, in which they compared the use of non-invasive mechanical ventilation (NIMV) and high-flow nasal cannula (HFNC) for the treatment of dyspnea in patients with advanced cancer. (internationalhighflownetwork.com)
  • Common clinical presentations include fever, cough, dyspnea and hemoptysis. (wikipedia.org)
  • Patients were asked to choose descriptions of their sensation(s) of breathlessness from a dyspnea questionnaire listing 19 descriptors. (nih.gov)
  • We found that patients could distinguish different sensations of breathlessness. (nih.gov)
  • It reduces the dyspnea overall perception and the anxiety component of breathlessness. (ersjournals.com)
  • They should routinely ask patients about the intensity of their breathlessness, which should then be documented in the medical record. (aafp.org)
  • Evaluation of dyspnea should include asking about the distress, meaning, and needs that come with breathlessness. (aafp.org)
  • Oxygen therapy is the standard of care for patients with hypoxemia, but only a limited number of studies have assessed the short-term effects of supplemental oxygen on breathlessness at rest in patients with advanced lung disease. (aafp.org)
  • Null hypothesis: The provision of home oxygen in patients who do not meet the Australian national guidelines for domiciliary oxygen does not improve the subjective sensation of breathlessness. (isrctn.com)
  • Participants will complete a study log twice a day for nine days (days -2 to 7) about the sensation of dyspnea using a 0-10 numeric rating scale (NRS) twice a day, sleep disturbance, breathlessness in the past 24 hours on the NRS, percentage relief of dyspnea, drowsiness, nasal irritation, performance status, vital signs, functional impact, and quality of life (QOL). (isrctn.com)
  • Designed as a regional resource for evaluation and management of breathlessness, the Dyspnea Center offers expertise in the latest noninvasive and invasive cardiopulmonary exercise techniques to help determine the cause of symptoms and enhance patient care. (uhhospitals.org)
  • The way to express breathlessness by patients is variable, and it can be difficult to assess objectively the intensity of dyspnoea [ 6 ]. (biomedcentral.com)
  • Patients use a host of different words and phrases to describe the sensation of breathlessness. (cancer.gov)
  • 4 ] Breathlessness was a complaint at presentation in 60% of 289 patients with lung cancer. (cancer.gov)
  • Objective To determine the efficacy of oral morphine in relieving the sensation of breathlessness in patients in whom the underlying aetiology is maximally treated. (bmj.com)
  • We observed statistically and clinically significant effects on patient-reported breathlessness, quality of life, and depression symptoms, as well as high patient satisfaction with the intervention components and delivery. (grantome.com)
  • We plan to train oncology nurses in delivering a dyspnea management intervention that incorporates behavioral techniques shown to be effective for improving breathlessness and reducing stress in patients with cancer. (grantome.com)
  • Up to three quarters of patients with terminal cancer experience dyspnea, and many patients near the end of life will present to the ED seeking help. (ebmedicine.net)
  • Approximately 94 percent of patients with chronic lung disease experience dyspnea in the last year of life. (aafp.org)
  • In 12 of 15 patients (80%), total dyspnea scores by CDS improved significantly after inhalation of furosemide (P = 0.007), especially concerning a reduced sense of effort (P = 0.013) and reduced anxiety (P = 0.04). (nih.gov)
  • Following PR, the MRC grade 2 dyspnoea group showed similar improvements in ISW, CRQ-D, HAD-Anxiety and HAD-Depression to the MRC grades 3/4 dyspnoea group ( table 1 ). (bmj.com)
  • Although patients with MRC dyspnoea grade 2 referred for PR have better exercise capacity and fewer symptoms of dyspnoea, anxiety or depression than patients with MRC dyspnoea grades 3/4, they show similar improvements with PR. (bmj.com)
  • One of the main barriers to regular activity is anxiety related to dyspnea. (clinicaltrials.gov)
  • Defined as a subjective experience of discomfort during breathing, dyspnea is described as a multidimensional phenomenon integrating both the impact dimension (daily disability), the sensory dimension (intensity of dyspnea) and the emotional dimension (unpleasant and anxiety-aspects). (clinicaltrials.gov)
  • An overall improvement in dyspnea, and more specifically in its emotional dimension, has been achieved by reducing dyspnea anxiety. (clinicaltrials.gov)
  • When patients return home left on their own again, dyspnea anxiety is likely to reappear and motivation may not be enough. (clinicaltrials.gov)
  • At rest and at peak of exercise, subjects were asked to rate 5 different dyspnea components (1:overall, 2:effort, 3:difficult inspiration, 4:difficult expiration, 5:anxiety) and leg discomfort. (ersjournals.com)
  • Patients who are alert may experience anxiety. (aacn.org)
  • Pain, dyspnea, and anxiety should be routinely assessed by patient self-report when possible. (aacn.org)
  • Evidence-based interventions are offered for both prevention and treatment of pain, dyspnea, anxiety, and delirium. (aacn.org)
  • Occasionally, neuromuscular disease and anxiety also cause dyspnea. (mhmedical.com)
  • Dyspnea is associated with impaired quality of life, decreased participation in social activities, symptoms of depression and anxiety, and even desire for death in patients with lung cancer. (grantome.com)
  • All participants will complete measures of dyspnea, quality of life, anxiety and depression symptoms, as well as activity level at baseline after completion of the intervention phase at 8, 16, and 24 weeks. (grantome.com)
  • 0.36 to 3.53 L, FVC 1.07 to 5.74 L. Dyspnea measures were assessed for test-retest reliability, internal consistency, interrater reliability, and construct validity (i.e.. correlations among dyspnea measures and correlations of dyspnea measures with exercise tolerance, health-related quality of life, lung function, anxiety, and depression). (naver.com)
  • The Dyspnea Self-Management Protocol involves a non-pharmacological approach to easing a patient's dyspnea and/or associated anxiety by providing tools and techniques to help them regain a more normal and relaxed breathing pattern. (orlandomedicalnews.com)
  • Mr. Burd instructed the patient on proper use of the fan along with structured breathing and anxiety-reducing relaxation techniques when dyspnea presented. (orlandomedicalnews.com)
  • For this individual, seeing was believing, as it dramatically increased her confidence in being able to maintain control and self-manage her anxiety/dyspnea episodes. (orlandomedicalnews.com)
  • Only in patients with hyperventilation from anxiety disorder, the diagnostic accuracy of pH and hypoxemia rendered valuable with an area under the receiver operating characteristics curve (AUC) of 0.86. (unibas.ch)
  • On the basis of the patient's unexplained progressive dyspnoea, impaired gas transfer and CT findings, an open VATS-assisted lung biopsy was performed. (bmj.com)
  • A high-resolution computed tomography scan could be considered if the dyspnea were progressive, but he has normal diffusing capacity of the lungs for carbon monoxide, suggesting that interstitial lung disease is highly unlikely. (acc.org)
  • The patient appears to be terminally ill, and when you ask her husband what's going on, he says, "She has lung cancer. (ebmedicine.net)
  • 1. This study was devised to test the hypothesis that dyspnoea could be mediated by unmyelinated vagal sensory nerve endings (type J receptors) situated at alveolar level in the lung. (portlandpress.com)
  • Obstructive lung disease was found in 52% of patients (35% with exercise-induced asthma and 12% with asthma), 10% had vocal cord dysfunction, and 14% had other diagnoses. (eurekamag.com)
  • Objectives: To evaluate the relationship between dyspnea as assessed by the Modified Medical Council Dyspnea (MMRC) scale, the Global Initiative for Chronic Obstructive Lung Disease (GOLD 2014) staging and indices of lung hyperinflation and spirometry. (scirp.org)
  • Methods: Data were retrospectively analyzed at a 600-bed tertiary care center including spirometry, plethysmographic lung volumes, single breath carbon monoxide diffusion capacity and dyspnea graded according to MMRC, and GOLD staging. (scirp.org)
  • Conclusions: Indices of lung hyperinflation are closely associated, with dyspnea as assessed by MMRC grading with TLC, RV/TLC and IC exhibiting the closest relations, more so than FEV 1 . (scirp.org)
  • These findings further support the concept that more than a reduction in FEV 1 , lung hyperinflation contributes to the sensation of dyspnea in airflow limitation. (scirp.org)
  • A secondary objective was to determine lung volume subdivisions most closely related to indices of dyspnea. (scirp.org)
  • Both the ASE and ACEP define the role of focused bedside TTE (F-TTE) and lung ultrasound as a time-sensitive assessment tool for the symptomatic patient, helping to narrow the differential diagnosis for a number of symptoms, including dyspnea. (com.pk)
  • In the interim, while awaiting laboratory results and chest X-ray imaging, POCUS with a three-point exam (F-TTE, IVC collapsibility, and lung ultrasound) was used for bedside evaluation of the etiology of the patient's dyspnea. (com.pk)
  • The patient had reduced LV systolic function without new or severe valvular pathology, a dilated, non-collapsing IVC, and diffuse B lines (left greater than right) on lung ultrasound imaging. (com.pk)
  • Patients with comparable degrees of functional lung impairment and disease burden may describe varying intensities of dyspnea. (cancer.gov)
  • BACKGROUND This consensus statement was developed based on the understanding that patients with advanced lung or heart disease are not being treated consistently and effectively for relief of dyspnea. (semanticscholar.org)
  • Measurement of dyspnea and quality of life in advanced lung disease. (semanticscholar.org)
  • For now, lung transplant is the only treatment of proven benefit for patients with the disease. (pulmonaryfibrosisnews.com)
  • Our multidisciplinary team recently conducted a pilot study examining the delivery of a brief, two-session behavioral intervention for dyspnea management in patients with advanced lung cancer. (grantome.com)
  • For the proposed project, we seek to build on our prior positive findings by conducting a randomized controlled trial (RCT) of the intervention in a larger sample of patients with advanced lung cancers. (grantome.com)
  • The specific aims of this study are to demonstrate the efficacy of the brief behavioral intervention for improving self-reported dyspnea (primary outcome) as well as quality of life, mood, and activity level (secondary outcomes) in patients with advanced lung cancer. (grantome.com)
  • Study Design & Methods: We will enroll and randomly assign up to 200 patients diagnosed with advanced lung cancer (100 per study group) to receive either the brief behavioral intervention for dyspnea or usual care. (grantome.com)
  • At least 50% of patients with advanced lung cancer experience debilitating dyspnea that is associated with worse medical and psychosocial outcomes. (grantome.com)
  • Subjects were 143 patients (74 women and 69 men) with obstructive lung disease, ages 40 to 86, FEV. (naver.com)
  • How should we measure function in patients with chronic heart and lung disease? (naver.com)
  • Although physiologic responses differed significantly according to the type of exercise that was chosen, dyspnea intensity, ventilation, and operating lung volumes were unaffected by the mode of exercise. (dontforgettobreathe.org.nz)
  • This modification was made to reflect the nature of the population l)eing studied, where a high prevalence of patients with asthma or chronic lung disease might be expected to lead to an overdiagnosis of congestive heart failure if this criterion were retained. (soheb.com)
  • In ES-SCLC, platinum-based combination chemotherapy is the standard of care, with radiotherapy added only to palliate symptoms such as dyspnea, pain from liver or bone metastases, or for treatment of brain metastases, which, in small-cell lung carcinoma, typically have a rapid, if temporary, response to whole brain radiotherapy. (wikipedia.org)
  • citation needed] In August 2018, the FDA approved nivolumab to treat patients with metastatic small cell lung cancer (SCLC) who failed to respond to platinum-based chemotherapy and at least one other line of treatment. (wikipedia.org)
  • 2 ] Because many advanced cancers spread to the thorax, symptoms such as dyspnea, cough, chest pain, or palpitations often present a challenge in sorting out the likely cause of the problem and developing appropriate interventions. (cancer.gov)
  • However, opioids were poorly tolerated in these patients during repeated administration, mostly because of sedation and nausea [5] . (annals.org)
  • These side effects usually disappear with the development of tolerance and are rarely a cause for discontinuing treatment among the approximately 80% of terminal cancer patients who receive opioids for pain [6] . (annals.org)
  • However, the effects of opioids on the dyspnea of cancer have not been the focus of prospective studies. (annals.org)
  • Unless contraindicated, prophylaxis with a gastrointestinal motility stimulant laxative and a stool softener is appropriate in terminally ill patients who are being given opioids. (aafp.org)
  • Constipation resulting from opioids is dose-related, and patients do not develop tolerance to this side effect. (aafp.org)
  • All patients for whom opioids are prescribed should be given a prophylactic gastrointestinal motility stimulant laxative and a stool softener, unless use of these agents is contraindicated. (aafp.org)
  • Opioids are the most effective and widely studied agents available for palliation of dyspnea in this population, while adjuvant therapies such as oxygen, noninvasive positive pressure ventilation, and hand-held fans may also be used. (ebmedicine.net)
  • Oral and parenteral opioids can improve dyspnea. (aafp.org)
  • We also describe dyspnoea management (especially taking into account the use of opioids) and compare its intensity and evolution in the two groups. (biomedcentral.com)
  • Some clinicians acknowledge that opioids have a role in the management of intractable dyspnoea. (bmj.com)
  • Diagnosis of HFpEF (case) or non-cardiac dyspnea (control) was determined by invasive hemodynamic exercise testing. (mdedge.com)
  • Twenty-four percent of patients had no specific diagnosis. (eurekamag.com)
  • What is the differential diagnosis of dyspnea? (mhmedical.com)
  • This in turn allows us to deduce a fairly comprehensive differential diagnosis of dyspnea. (mhmedical.com)
  • POCUS with a small, extremely portable device had allowed for convenient and rapid evaluation, diagnosis, and intervention in a complex patient. (com.pk)
  • Results Of the 776 patients enrolled, 491 had a final diagnosis of AHF with responses at both time points. (elsevier.com)
  • The patient is stabilized and transferred to the ICU with a presumed diagnosis of aspiration pneumonia and septic shock. (ahrq.gov)
  • The diagnosis of patients with dyspnea. (ahrq.gov)
  • The proportion of patients not receiving ambulance transportation was higher among patients diagnosed with PPU/PUB compared to patients diagnosed with an FHQ diagnosis. (springer.com)
  • Maximal inspiratory mouth pressure (PImax), ?2-agonist consumption, and perception of dyspnea (POD) were measured in 22 women and 22 men with mild persistent-to- moderate asthma. (powerbreathe.com)
  • A 69-year old man complained of dyspnea, and cough. (comu.edu.tr)
  • A cardiopulmonary test could be useful to assess the workload that the patient can achieve, the degree of dyspnea experienced, the peak oxygen uptake, cardiac output (calculated from carbon dioxide production and oxygen uptake), and relationship of minute ventilation to carbon dioxide production. (acc.org)
  • Several factors have been found to predict adverse outcome in this disease, like degree of dyspnea, exercise capacity, body mass index, and degree of airway obstruction, as measured using FEV 1 . (rcjournal.com)
  • Conclusion A 10.5 mm change is the MCID for improvement in dyspnea over 6 h in ED patients with AHF. (elsevier.com)
  • Both therapies, NIMV and HFNC were associated with an improvement in dyspnea measured in the NRS and MBS scales, but there were no statistically significant differences between them (see table). (internationalhighflownetwork.com)
  • Changes in outcomes between patients with MRC grade 2 and those with MRC grades 3 or 4 dyspnoea before and after PR were compared using t tests or Mann-Whitney tests. (bmj.com)
  • We have provided nurse researchers with an alternative to CTT when developing or refining questionnaires that measure patient-centred outcomes. (salford.ac.uk)
  • The primary outcomes of interest are the epidemiology and outcome of these patients. (edu.au)
  • Increasingly, the reliability of physiological parameters such as FEV 1 to predict patient-centered outcomes has been brought into question. (scirp.org)
  • The Multiple Chronic Conditions Resource Center provides FREE resources to educate, update and promotes best practices that ensure optimal patient-centered outcomes. (multiplechronicconditions.org)
  • These results are significant for patients with relapsed multiple myeloma, who are faced with worse outcomes each time they experience a relapse. (prnewswire.com)
  • KYPROLIS now offers patients with relapsed or refractory multiple myeloma the option of a more convenient dosing regimen that provides better outcomes with a comparable safety profile,' said David M. Reese , M.D., executive vice president of Research and Development at Amgen. (prnewswire.com)
  • A 41-year-old with idiopathic myelofibrosis was referred to the chest clinic with a 1-month history of progressive dyspnoea and intermittent wheeze. (bmj.com)
  • Laboratory evaluation yielded positive results in less than 5% of patients, and cardiac evaluation was normal in all patients. (eurekamag.com)
  • Methods The study prospectively investigated the prognostic value of the biomarkers N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity cardiac troponin T (hs-cTnT), Cystatin-C (Cys-C), high-sensitivity C-reactive protein (hs-CRP), and Galectin-3 (Gal-3) for 90-day mortality in 603 patients presenting to the ED with dyspnea as primary complaint. (onlinejacc.org)
  • Cardiac conditions that may precipitate dyspnea include left ventricular systolic or diastolic dysfunction, arrhythmias, valvular disease, pericardial disease, myocardial infarction (MI), and intracardiac or extracardiac shunts. (patientcareonline.com)
  • Although assessment of proportional pulse pressure (PPP) was not included in our original study design, a recent report indicated a correlation between the PPP ([systolic BP - diastolic BP] / systolic BP) and hemodynamic measurements in patients with congestive heart failure, with a PPP of less than 0.25 significantly predicting abnormal cardiac index at catheterization. (soheb.com)
  • Unilateral diaphragm paralysis is an often not recognized cause of dyspnea especially after cardiac surgery procedures. (biomedcentral.com)
  • Conclusions Patients with unexplained dyspnea have a high likelihood of ischemia and an increased incidence of cardiac events. (elsevier.com)
  • As previously discussed, patients with MM can develop cardiac amyloidosis. (fullcontentrss.com)
  • 0.001), but comparable to the 30-day mortality among patients diagnosed with cardiac chest pain ( P = 0.080) and trauma ( P = 0.281). (springer.com)
  • Patient care begins with an evaluation at the clinic, which is open Mondays from 8 a.m. to noon and located on Cox 2 at our downtown Boston campus. (massgeneral.org)
  • By then, though, the patient had already been given aggressive diuretic therapy, received escalating ionotropic support, bronchoscopy was set up at the bedside for endobronchial evaluation after the intubation given his fevers, and the family had been notified. (com.pk)
  • Objectives The purpose of this study was to characterize the outcome of patients referred for exercise echocardiographic evaluation of dyspnea. (elsevier.com)
  • Methods: 43 patients with dyspnea were included in the study. (scitechnol.com)
  • METHODS: We conducted a post hoc analysis of 387 patients [39% female, mean (SD) age 57.6 (14.5) years] presenting to the emergency department with dyspnea and followed for 1 year (97% complete follow-up). (elsevier.com)
  • Methods We identified 443 patients with unexplained dyspnea, 2,033 with chest pain, and 587 with both symptoms referred for exercise echocardiography. (elsevier.com)
  • Effect of nebulized furosemide in terminally ill cancer patients with dyspnea. (nih.gov)
  • Inhalation of nebulized furosemide appears to be effective against dyspnea in terminally ill cancer patients. (nih.gov)
  • Management of Common Symptoms in Terminally Ill Patients: Part II. (aafp.org)
  • This is part II of a two-par article on the management of common symptoms in terminally ill patients. (aafp.org)
  • Constipation is a frequent cause of nausea and vomiting in terminally ill patients. (aafp.org)
  • In terminally ill patients with low performance status, surgical treatment of bowel obstruction is not appropriate because of high mortality and recurrence rates. (aafp.org)
  • Faced with this clearly uncomfortable, dying patient, the traditional emergency medicine tools of endotracheal intubation and mechanical ventilation seem inappropriate, but what other medical strategies exist to help this distressed, symptomatic patient? (ebmedicine.net)
  • Three systematic reviews of noninvasive positive pressure ventilation concluded that it improved the patient's perception of dyspnea. (aafp.org)
  • Significant lower dyspnoea (primary outcome), leg discomfort, minute ventilation and capillary blood lactate under the ECT condition were found, with no change in total task time. (onmedica.com)
  • In some cases diaphragm paralysis disables to wean patient from ventilation. (biomedcentral.com)
  • During next two days progressive dyspnea was observed and patient became ventilation dependent. (biomedcentral.com)
  • The results of this study show that high-flow therapy is at least as effective as non-invasive ventilation in the treatment of dyspnea in cancer patients, but is better tolerated. (internationalhighflownetwork.com)
  • In the STABILITY (Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy) trial, there was reduction in mortality from increasing habitual exercise intensity and/or exercise duration relative to current activity levels in patients with stable coronary artery disease. (acc.org)
  • Each case of dyspnea must be evaluated on an individual basis in order to assess the intensity of the distinct sensations, the stress involved, and its burden on a person's quality of life. (multiplechronicconditions.org)
  • In addition, many patients tend to self-limit the intensity of their physical activity and might not feel incapacitating dyspnoea despite being in poor functional class [ 7 ]. (biomedcentral.com)
  • Additionally, we aim to ascertain the factors associated with the persistence of a severe intensity of dyspnea at hospital discharge. (biomedcentral.com)
  • 6 ] About one-third of patients who could report the intensity of their dyspnea rated it as moderate to severe. (cancer.gov)
  • Nine hundred and twenty-three cancer outpatients completed visual analogue scales (VAS) and verbal rating scales (VRS-D) to assess the intensity of their dyspnea. (elsevier.com)
  • Dyspnea is a subjective feeling of difficulty of breath and could be due to many causes. (scitechnol.com)
  • In addition, patients with AF had higher in-hospital mortality (13% versus 6%, P=0.012). (unibas.ch)
  • On multivariate analysis, only 6MWT distance and dyspnea after the test correlated independently with mortality ( P = .005 for both variables). (rcjournal.com)
  • The 30-day mortality rate among patients diagnosed with PPU/PUB was 7.8% (CI: 4.2-11.1). (springer.com)
  • Among patients calling 1-1-2, fewer patients diagnosed with PPU/PUB received ambulance transportation than patients diagnosed with FHQ diagnoses, despite a high mortality among patients diagnosed with PPU/PUB. (springer.com)
  • The team also found that one in three patients reported chest pain. (pulmonaryfibrosisnews.com)
  • Results Compared to those with chest pain alone, patients referred for dyspnea alone were older, predominately men, and had lower workload, lower ejection fraction (EF), more prior myocardial infarction (MI), and abnormal rest electrocardiograms. (elsevier.com)
  • Exercise echocardiography showed ischemia in 42% of patients with dyspnea, 19% with chest pain, and 58% with both symptoms. (elsevier.com)
  • Pursed-lip breathing, a breathing strategy often used by patients with airway obstruction, can provide relief of dyspnea. (aafp.org)
  • Understanding the characteristics of these patients, the range of diagnoses and their outcome can help inform training and planning of services. (edu.au)
  • Background Little information exists regarding outcome of patients with dyspnea. (elsevier.com)
  • Although dyspnea is often considered a single sensation, alternatively it may encompass multiple sensations that are not well explained by a single physiologic mechanism. (nih.gov)
  • Additional post hoc factor analysis provided similar results when the sample was divided into two subgroups by randomization, by severity of dyspnea ratings, or by severity of airflow obstruction. (nih.gov)
  • How well do patients and providers agree on the severity of dyspnea? (semanticscholar.org)
  • Three different instruments were used to rate dyspnea: a modified Medical Research Council (MRC) scale, the oxygen cost diagram (OCD), and the baseline dyspnea index (BDI). (nih.gov)
  • A prevalence of BTP of up to 66% has been observed in cancer patients. (springer.com)
  • Because obesity is a heterogeneous condition, with variable genetic associations, co-morbidities and distributions of adipose tissue, the study focused on patients with abdominal obesity who met diagnostic criteria for metabolic syndrome. (clinicaltrials.gov)
  • Studies advocating point-of-care ultrasound (POCUS) for the assessment of unstable patients by non-cardiologists were first published over twenty years ago because of the feasibility, time-effectiveness, and diagnostic accuracy of POCUS when compared to more invasive measures. (com.pk)
  • Patients were randomly assigned to a diagnostic strategy with or without the use of BNP. (unibas.ch)
  • This finding should be taken into account when considering diagnostic tests and treatment strategies for patients with advanced IPF. (pulmonaryfibrosisnews.com)
  • Referral to the "wrong" specialism could result in diagnostic- and treatment delay, which results in discomfort and uncertainty for the patient. (ijic.org)
  • Does inappropriate selectivity in information use relate to diagnostic errors and patient harm? (ahrq.gov)
  • Inappropriate selectivity (failure to consider all available information or potential diagnoses) was a major contributor to diagnostic errors in patients with dyspnea. (ahrq.gov)
  • Dyspnea was evaluated using the Cancer Dyspnea Scale (CDS) before and 60 min after inhalation. (nih.gov)
  • Three instruments are available to measure dyspnea: the Borg scale, visual analog scale, and numerical rating scale. (aafp.org)
  • 0-10 Numeric rating scale for dyspnoea. (isrctn.com)
  • Surveys quantifying dyspnoea (Numerical Rating Scale 1-10) and quality of life (EuroQoL 5d) were administered at discharge. (biomedcentral.com)
  • HF patients had worse EuroQoL 5d scores than those with RD, due to mobility problems (118 [62.1%] vs. 28 [41.8%], p =0.004), and lower punctuation in Visual Analogue Scale (57.9±1.6 vs. 65.6±1.0, p =0.006). (biomedcentral.com)
  • Dyspnea was assessed with a numerical scale (NRS) and modified Borg scale (MBS) before and after the intervention. (internationalhighflownetwork.com)
  • Dyspnea is one of the most distressing symptoms experienced by dying patients, and it is a common reason for such patients to seek care in the emergency department. (ebmedicine.net)
  • Objectives The study aim was to determine the prognostic value of a multimarker strategy for risk-assessment in patients presenting to the emergency department (ED) with dyspnea. (onlinejacc.org)
  • Bruera E, MacEachern T, Ripamonti C, Hanson J. Subcutaneous Morphine for Dyspnea in Cancer Patients. (annals.org)
  • You have read that patients often receive morphine at the end of life, but you don't want to be accused of hastening anyone's death. (ebmedicine.net)
  • One review of 13 studies of persons with a variety of advanced chronic diseases found that morphine was effective for treating dyspnea. (aafp.org)
  • He used the opiates around the clock and his morphine dose was increased to 10 mg orally every 4 hours around the clock and 5 mg orally every 2 hours for breakthrough dyspnea, which he would take before he had to move around. (clinmedjournals.org)
  • Participants reported significantly different dyspnoea scores when treated with morphine: an improvement of 6.6 mm (95% confidence interval 1.6 mm to 11.6 mm) in the morning and of 9.5 mm (3.0 mm to 16.1 mm) in the evening (P = 0.011 and P = 0.006, respectively). (bmj.com)
  • Conclusions Sustained release, oral morphine at low dosage provides significant symptomatic improvement in refractory dyspnoea in the community setting. (bmj.com)
  • We evaluated the effect of ultrasonically nebulized furosemide (20 mg) on dyspnea uncontrollable by standard therapy in patients with terminal cancer. (nih.gov)
  • It occurs in approximately 29% to 74% of patients with terminal cancer [2, 3] and is perceived as one of the most devastating symptoms by the patient and the family. (annals.org)
  • Part I of this two-part article reviewed the management of fatigue, anorexia, cachexia, nausea and vomiting in patients with cancer, acquired immunodeficiency syndrome (AIDS) and other terminal illnesses. (aafp.org)
  • Mechanical bowel obstruction occurs in approximately 3 percent of patients with cancer who are receiving hospice care. (aafp.org)
  • Cancer patients often have comorbid medical problems in addition to their underlying malignant disorders. (cancer.gov)
  • 1 ] Whether patients are seen in primary care or cancer care settings, unexplained symptoms often frustrate physicians and patients. (cancer.gov)
  • Evidence-based recommendations have been published describing various approaches to the problems of cancer-related fatigue, anorexia, depression, and dyspnea. (cancer.gov)
  • Clinicians caring for cancer patients should be familiar with the assessment and treatment of common conditions that manifest as chest symptoms. (cancer.gov)
  • Perspectives on comorbidity and cancer in older patients: approaches to expand the knowledge base. (cancer.gov)
  • Another study revealed that half of patients with advanced cancer scored their dyspnea as moderate to severe. (cancer.gov)
  • The approval of Kyprolis in combination provides physicians and patients across Europe with an important new treatment option for relapsed multiple myeloma, helping to address a real unmet need for this rare blood cancer,' said Sean E. Harper , M.D., executive vice president of Research and Development at Amgen. (prnewswire.com)
  • Multiple myeloma is a complex blood cancer that often becomes resistant to treatment, which is why there is a need for new therapeutic options that provide deep and durable responses to extend the time patients live without their disease progressing. (prnewswire.com)
  • We're pleased that the FDA has recognized the importance of bringing more treatment options to cancer patients more quickly through its pilot programs and proud to participate with this KYPROLIS data. (prnewswire.com)
  • While great progress has been made in the last decade, multiple myeloma remains an incurable disease characterized by a recurring pattern of remission and relapse, and it is important that patients have treatment options that meet their individual needs,' said David S. Siegel , M.D., Ph.D., chief of the Division of Multiple Myeloma at John Theuer Cancer Center at Hackensack University Medical Center. (prnewswire.com)
  • The purpose of the present investigation is to test a brief behavioral intervention for dyspnea, delivered by oncology nurses within the outpatient cancer clinic. (grantome.com)
  • These patients face life-limiting illnesses such as cancer, C.O.P.D., heart disease, stroke, and dementia. (orlandomedicalnews.com)
  • The scope of BTP costs in cancer patients is unknown. (springer.com)
  • The purpose of this study was to evaluate the economic cost of BTP in patients with cancer and the relationship with their quality of life. (springer.com)
  • The study showed the results of the first real-life prospective study evaluating the cost of illness of BTP in cancer patients demonstrating that the presence of breakthrough pain in a cancer patient causes a very significant increase in healthcare costs. (springer.com)
  • The aim of this study was to measure the economic impact of breakthrough pain in cancer patients in a prospective follow-up. (springer.com)
  • High Flow Oxygen vs Bilevel Positive Airway Pressure for dyspnea in patients with advanced cancer. (internationalhighflownetwork.com)
  • High Flow Oxygen and Bilevel Positive Airway Pressure for persistent dyspnea in patients with advanced cancer: A phase II randomized trial. (internationalhighflownetwork.com)
  • HF patients have less dyspnoea than patients with RD but present worse quality of life. (biomedcentral.com)
  • Some patient's and treatment characteristics may be associated with a higher probability of presenting severe dyspnea. (biomedcentral.com)
  • Obese patients are believed to experience greater dyspnea than normal weight individuals during walking exercises, but questions have been raised as to whether dyspnea measurement during the cycle test, where leg muscles are selectively stressed, accurately reflects normal daily activities, explain Denis O'Donnell Queen's University & Kingston General Hospital, Ontario, Canada and colleagues. (dontforgettobreathe.org.nz)
  • This study evaluated the ability of the BDI and TDI to measure dyspnea in 46 subjects with ALS. (elsevier.com)
  • Baseline dyspnea was assessed using the baseline dyspnea index.The effect of weight loss on dyspnea was assessed using the transitional dyspnea index. (clinicaltrials.gov)
  • The baseline dyspnea index (BDI) and transition dyspnea index (TDI) are indices designed to measure change in dyspnea over time. (elsevier.com)
  • Effect of Fentanyl Versus Placebo for Exercise-Induced and Breakthrough Dyspnea [ Time Frame: Baseline to 100 minutes for study participation. (clinicaltrials.gov)