11-Hydroxycorticosteroids: A group of corticosteroids bearing a hydroxy group at the 11-position.Fractures, Bone: Breaks in bones.Fracture Healing: The physiological restoration of bone tissue and function after a fracture. It includes BONY CALLUS formation and normal replacement of bone tissue.Hip Fractures: Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).Femoral Fractures: Fractures of the femur.Spinal Fractures: Broken bones in the vertebral column.Fracture Fixation, Internal: The use of internal devices (metal plates, nails, rods, etc.) to hold the position of a fracture in proper alignment.Fractures, Comminuted: A fracture in which the bone is splintered or crushed. (Dorland, 27th ed)Fracture Fixation: The use of metallic devices inserted into or through bone to hold a fracture in a set position and alignment while it heals.Osteoporotic Fractures: Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.Radius FracturesFractures, Spontaneous: Fractures occurring as a result of disease of a bone or from some undiscoverable cause, and not due to trauma. (Dorland, 27th ed)Fractures, Stress: Fractures due to the strain caused by repetitive exercise. They are thought to arise from a combination of MUSCLE FATIGUE and bone failure, and occur in situations where BONE REMODELING predominates over repair. The most common sites of stress fractures are the METATARSUS; FIBULA; TIBIA; and FEMORAL NECK.Femoral Neck Fractures: Fractures of the short, constricted portion of the thigh bone between the femur head and the trochanters. It excludes intertrochanteric fractures which are HIP FRACTURES.Ulna Fractures: Fractures of the larger bone of the forearm.Fracture Fixation, Intramedullary: The use of nails that are inserted into bone cavities in order to keep fractured bones together.Rib FracturesSkull Fractures: Fractures of the skull which may result from penetrating or nonpenetrating head injuries or rarely BONE DISEASES (see also FRACTURES, SPONTANEOUS). Skull fractures may be classified by location (e.g., SKULL FRACTURE, BASILAR), radiographic appearance (e.g., linear), or based upon cranial integrity (e.g., SKULL FRACTURE, DEPRESSED).Mandibular Fractures: Fractures of the lower jaw.Tooth Fractures: Break or rupture of a tooth or tooth root.Fractures, Compression: Crumbling or smashing of cancellous BONE by forces acting parallel to the long axis of bone. It is applied particularly to vertebral body fractures (SPINAL FRACTURES). (Blauvelt and Nelson, A Manual of Orthopedic Terminology, 1994, p4)Intra-Articular Fractures: Fractures of the articular surface of a bone.Osteoporosis: Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.Bone Plates: Implantable fracture fixation devices attached to bone fragments with screws to bridge the fracture gap and shield the fracture site from stress as bone heals. (UMDNS, 1999)Bone Nails: Rods of bone, metal, or other material used for fixation of the fragments or ends of fractured bones.Orbital Fractures: Fractures of the bones in the orbit, which include parts of the frontal, ethmoidal, lacrimal, and sphenoid bones and the maxilla and zygoma.Colles' Fracture: Fracture of the lower end of the radius in which the lower fragment is displaced posteriorly.Bony Callus: The bony deposit formed between and around the broken ends of BONE FRACTURES during normal healing.Bone Density: The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.Periprosthetic Fractures: Fractures around joint replacement prosthetics or implants. They can occur intraoperatively or postoperatively.Bone Screws: Specialized devices used in ORTHOPEDIC SURGERY to repair bone fractures.Wrist Injuries: Injuries to the wrist or the wrist joint.Athletes: Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.Hepatitis, Infectious Canine: A contagious disease caused by canine adenovirus (ADENOVIRUSES, CANINE) infecting the LIVER, the EYE, the KIDNEY, and other organs in dogs, other canids, and bears. Symptoms include FEVER; EDEMA; VOMITING; and DIARRHEA.Sports Medicine: The field of medicine concerned with physical fitness and the diagnosis and treatment of injuries sustained in exercise and sports activities.Female Athlete Triad Syndrome: A condition of competitive female athletes in which there are interrelated problems of EATING DISORDERS; AMENORRHEA; and OSTEOPOROSIS.Sports: Activities or games, usually involving physical effort or skill. Reasons for engagement in sports include pleasure, competition, and/or financial reward.Physicians: Individuals licensed to practice medicine.Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.United StatesTibial FracturesFractures, Closed: Fractures in which the break in bone is not accompanied by an external wound.Fractures, Open: Fractures in which there is an external wound communicating with the break of the bone.Drugs, Investigational: Drugs which have received FDA approval for human testing but have yet to be approved for commercial marketing. This includes drugs used for treatment while they still are undergoing clinical trials (Treatment IND). The main heading includes drugs under investigation in foreign countries.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Embolism, Fat: Blocking of a blood vessel by fat deposits in the circulation. It is often seen after fractures of large bones or after administration of CORTICOSTEROIDS.Dictionaries, MedicalPulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.Dictionaries as Topic: Lists of words, usually in alphabetical order, giving information about form, pronunciation, etymology, grammar, and meaning.Intracranial Embolism: Blocking of a blood vessel in the SKULL by an EMBOLUS which can be a blood clot (THROMBUS) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with HEART DISEASES. Other non-cardiac sources of emboli are usually associated with VASCULAR DISEASES.Lipectomy: Removal of localized SUBCUTANEOUS FAT deposits by SUCTION CURETTAGE or blunt CANNULATION in the cosmetic correction of OBESITY and other esthetic contour defects.Embolism: Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
  • a respiratory distress syndrome that can occur during long bone fractures that result from the release of bone marrow elements into the circulatory system that accumulate in the lungs to affect gas exchange adversely. (thefreedictionary.com)
  • The plug enters the circulatory system after the fracture of a long bone or, less commonly, after traumatic injury to adipose tissue or to a fatty liver. (thefreedictionary.com)
  • The mechanical theory states that trauma disrupts fat cells and tears veins in the bone marrow at the site of a fracture. (thefreedictionary.com)
  • 2. Li ZC, Dai LY, Jiang LS, Qiu S. Difference in subchondral cancellous bone between postmenopausal women with hip osteoarthritis and osteoporotic fracture: implication for fatigue microdamage, bone microarchitecture, and biomechanical properties. (acr.org)
  • where a force and stress was applied to the limb will often determine the type of fracture that results (compound, simple, greensick, displaced, comminuted, segmental spiral, hairline) [we're getting into a little physics here. (allnurses.com)
  • Management often includes diets, exercise, etc, yet it depends on the type of fracture. (spiritualwellnessandhealing.com)
  • The 2013 definition, which used newer data to improve the precision of the definition, made the location of the fracture (just below the lesser trochanter but above the supracondylar flare) a sine qua non, rather than a major feature, delineated five major features, and required that a minimum of four be present. (springer.com)
  • To summarize reports published since the 2013 American Society of Bone and Mineral Research Task Force Report on atypical femoral fractures (AFF). (springer.com)
  • ASBMR Updates Report on Atypical Femoral Fractures: Discussion with Task Force Co-chairs Elizabeth Shane, M.D. and David Burr, Ph.D. (asbmr.org)
  • Earlier this year, an update to the ASBMR Task Force on Atypical Femoral Fractures (AFF) seminal 2010 report was published on JBMR ® Online . (asbmr.org)
  • However, recognition of these risks has prompted physicians to target therapy towards patients at high risk of fracture and to consider the optimal duration of therapy with anti-remodeling agents. (asbmr.org)
  • 2 , 3 Damage to large arteries in CKD patients has been described in the last years and is mainly characterized by an outward remodeling of the carotid artery without wall thickening, leading to an increased circumferential wall stress, and by an increased aortic and carotid stiffness. (asnjournals.org)
  • Patients may still be able to ambulate with a non-displaced fatigue femoral neck fracture. (lecturio.com)
  • In patients with suspected sports related stress fractures of the hip and normal radiographs, MRI of the entire pelvis should be the next imaging modality for evaluation. (acr.org)
  • Conscious patients with rib fracture frequently complain of pain on inspiration and dyspnea. (boneandspine.com)
  • Recent meta-analyses have revealed that the risk of bone fracture is increased in both type 1 and type 2 diabetic patients. (eurekaselect.com)
  • In the United States, 320,000 elderly patients sustain hip fractures annually-this is expected to increase as the population ages ( 4 ). (unboundmedicine.com)
  • Unfortunately standard transthoracic stress echocardiography is often suboptimal in obese patients because of paucity of echogenicity. (biomedcentral.com)
  • Transesophageal echocardiography provides superior quality cardiac imaging and transesophageal dobutamine stress echocardiography (TE-DSE) compares favourably with myocardial scintigraphy for the detection of myocardial ischemia in non severely obese patients [ 8 ]. (biomedcentral.com)
  • We believe that serum calcium levels should be checked in patients with stress fractures, and if the serum calcium is low, hypoparathyroidism should be considered. (biomedcentral.com)
  • A previous study showed that the prevalence of fragility fractures is greater in patients with hypoparathyroidism [ 5 ]. (biomedcentral.com)
  • As GIO is an important problem due to the increased risk of fracture, preventive measures are suggested in order to stabilize or increase the BMD in such patients, and consequently reduce the risk of fracture. (pubmedcentralcanada.ca)
  • In this pilot study we acquired CSF specimens at the onset of spinal anaesthesia in patients undergoing hip fracture surgery, and compared CSF and plasma cortisol levels in delirium cases versus controls. (biomedcentral.com)
  • Additionally, up to 25% of hip fracture patients may require long-term nursing home care, and only a third fully regain their prefracture level of independence. (drarchik.com)
  • The high morbidity and consequent dependency associated with these fractures strain interpersonal relationships and social roles for patients and their families. (drarchik.com)
  • Careful investigation should be considered in patients on long-term antiresorptive therapy presenting with bony tenderness to exclude an atypical fracture. (bvsalud.org)
  • Sternal fractures are more common in older patients, and this is thought to be due to the more elastic chest wall of younger patients. (statpearls.com)
  • Cardiac monitoring and pulse oximetry should be obtained in all patients with sternal fractures while in the emergency department. (statpearls.com)
  • To provide validation data on stress-rest CTP protocols as additive tools to improve the accuracy of multidetector computed tomography (MDCT) for coronary artery disease (CAD) in symptomatic patients. (biomedsearch.com)
  • Therefore, in this paper, I review the pathophysiological role of the AGEs-RAGE-oxidative stress system in decreased BMD and increased bone fragility in diabetes. (eurekaselect.com)
  • In subsamples of two additional cohorts, one in males and one in females, a positive association was seen between milk intake and both urine 8-iso-PGF2α (a biomarker of oxidative stress) and serum interleukin 6 (a main inflammatory biomarker). (bmj.com)
  • 4 5 6 7 Even a low dose of D-galactose induces changes that resemble natural aging in animals, including shortened life span caused by oxidative stress damage, chronic inflammation, neurodegeneration, decreased immune response, and gene transcriptional changes. (bmj.com)
  • Oxidative stress contributes to the complex pathophysiology of sickle cell disease. (bioportfolio.com)
  • Oxidative stress, antioxidant capacity, biomolecule damage, and inflammation symptoms of sickle cell disease in children. (bioportfolio.com)
  • Major basic processes, caused by genetic, environmental, and endogenous factors, in addition to abnormal protein dynamics with defective degradation due to deficiency of the ubiquitin-proteosomal-autophagy system, include oxidative stress and free radical formation, impaired bioenergetics and mitochondrial dysfunction, disruption of neuronal Golgi apparatus and transport, molecular chaperones, neurotrophins and "neuroinflammatory" processes. (springermedizin.de)
  • The periosteal stress reaction at the fracture site, which is thought to represent callus formation and is sometimes referred to as "beaking," was changed from a minor to a major feature. (asbmr.org)
  • Physicians and health care providers should maintain a high index of suspicion for stress fractures in runners presenting with insidious onset of focal bone tenderness associated with recent changes in training intensity or regimen. (acr.org)
  • In the updated report, the major and minor features have been revised and refined to be consistent with new data, and to distinguish AFF from ordinary osteoporotic fractures of the femoral diaphysis. (asbmr.org)