A condition in which there is a change of one adult cell type to another similar adult cell type.
A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.
Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.
GASTRITIS with atrophy of the GASTRIC MUCOSA, the GASTRIC PARIETAL CELLS, and the mucosal glands leading to ACHLORHYDRIA. Atrophic gastritis usually progresses from chronic gastritis.
A glandular epithelial cell or a unicellular gland. Goblet cells secrete MUCUS. They are scattered in the epithelial linings of many organs, especially the SMALL INTESTINE and the RESPIRATORY TRACT.
Tumors or cancer of the STOMACH.
The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
That part of the STOMACH close to the opening from ESOPHAGUS into the stomach (cardiac orifice), the ESOPHAGOGASTRIC JUNCTION. The cardia is so named because of its closeness to the HEART. Cardia is characterized by the lack of acid-forming cells (GASTRIC PARIETAL CELLS).
High molecular weight mucoproteins that protect the surface of EPITHELIAL CELLS by providing a barrier to particulate matter and microorganisms. Membrane-anchored mucins may have additional roles concerned with protein interactions at the cell surface.
Inflammation of the DUODENUM section of the small intestine (INTESTINE, SMALL). Erosive duodenitis may cause bleeding in the UPPER GI TRACT and PEPTIC ULCER.
A gel-forming mucin that is primarily found on the surface of gastric epithelium and in the RESPIRATORY TRACT. Mucin 5AC was originally identified as two distinct proteins, however a single gene encodes the protein which gives rise to the mucin 5A and mucin 5C variants.
The section of the alimentary canal from the STOMACH to the ANAL CANAL. It includes the LARGE INTESTINE and SMALL INTESTINE.
Endoscopic examination, therapy or surgery of the esophagus.
The development of bony substance in normally soft structures.
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
Endoscopic examination, therapy or surgery of the interior of the stomach.
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
A gel-forming mucin found predominantly in SMALL INTESTINE and variety of mucous membrane-containing organs. It provides a protective, lubricating barrier against particles and infectious agents.
A malignant epithelial tumor with a glandular organization.
A gel-forming mucin that is predominantly associated with the gastric epithelium.
The region between the sharp indentation at the lower third of the STOMACH (incisura angularis) and the junction of the PYLORUS with the DUODENUM. Pyloric antral glands contain mucus-secreting cells and gastrin-secreting endocrine cells (G CELLS).
Epithelial cells that line the basal half of the GASTRIC GLANDS. Chief cells synthesize and export an inactive enzyme PEPSINOGEN which is converted into the highly proteolytic enzyme PEPSIN in the acid environment of the STOMACH.
Tumors or cancer of the ESOPHAGUS.
The area covering the terminal portion of ESOPHAGUS and the beginning of STOMACH at the cardiac orifice.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
The viscous secretion of mucous membranes. It contains mucin, white blood cells, water, inorganic salts, and exfoliated cells.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
Mucins that are found on the surface of the gastric epithelium. They play a role in protecting the epithelial layer from mechanical and chemical damage.
The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
Pathological processes involving the STOMACH.
Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
A type II keratin found associated with KERATIN-19 in ductal epithelia and gastrointestinal epithelia.
An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
A type I keratin expressed predominately in gastrointestinal epithelia, MERKEL CELLS, and the TASTE BUDS of the oral mucosa.
Large, branched, specialized sweat glands that empty into the upper portion of a HAIR FOLLICLE instead of directly onto the SKIN.
A species of HELICOBACTER that colonizes in the STOMACH of laboratory MICE; CATS; and DOGS. It is associated with lymphoid follicular hyperplasia and mild GASTRITIS in CATS.
A PEPTIC ULCER located in the DUODENUM.
Endoscopic examination, therapy or surgery of the gastrointestinal tract.
Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
The larger air passages of the lungs arising from the terminal bifurcation of the TRACHEA. They include the largest two primary bronchi which branch out into secondary bronchi, and tertiary bronchi which extend into BRONCHIOLES and PULMONARY ALVEOLI.
Exclusive legal rights or privileges applied to inventions, plants, etc.
A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
A protein of the annexin family that catalyzes the conversion of 1-D-inositol 1,2-cyclic phosphate and water to 1-D-myo-inositol 1-phosphate.
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
A novel composition, device, or process, independently conceived de novo or derived from a pre-existing model.
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Property, such as patents, trademarks, and copyright, that results from creative effort. The Patent and Copyright Clause (Art. 1, Sec. 8, cl. 8) of the United States Constitution provides for promoting the progress of science and useful arts by securing for limited times to authors and inventors, the exclusive right to their respective writings and discoveries. (From Black's Law Dictionary, 5th ed, p1014)
"Intraocular osseous metaplasia. A clinico-pathological study". Indian J Ophthalmol. 50 (3): 183-8. PMID 12355691.CS1 maint: ... a clinico-pathological correlation of a rare disease and review of literature". Clin Ophthalmol. 6: 2049-57. doi:10.2147/OPTH. ... clinico-pathological profiles, management and outcomes". J Cancer Res Ther. 10 (2): 294-8. doi:10.4103/0973-1482.136570. PMID ...
This is the condition behind the pathological lesions found in the bladder wall, ureter and renal; and also tumour, both benign ... Infections are characterized by pronounced acute inflammation, squamous metaplasia, blood and reactive epithelial changes. ... Under normal situation, the eggs released into the bladder do not cause pathological symptoms. But eggs often fail to penetrate ... When eggs are released, they sometimes become permanently stuck in the bladder and cause pathological symptoms. The eggs are ...
Pathological effects on the bile ducts include inflammation, epithelial desquamation, goblet-cell metaplasia, epithelial and ...
Pathological effects on the bile ducts including inflammation, epithelial desquamation, goblet cell metaplasia, epithelial and ... This creates the pathological lesions found in the bladder wall, ureter and renal; and also tumour, both benign and malignant. ...
Most prominent pathological changes observed are nasal airway epithelial metaplasia in which goblet cells replace ciliated ...
A pathological stimulus could be responsible for inducing precursor cells (mesothelial stem cells) of the pleura or peritoneum ... Coelomic metaplasia theory: the pleura and peritoneum share the same embryological origin, both derived from mesothelium. ... The pleural and/or diaphragmatic lesions were always found on the left side, which supports the theory of coelomic metaplasia.[ ... Preserving lung parenchyma is a priority while removing macroscopic signs of pathological tissue. Medical treatment can include ...
The newly pathological sites, then, are metastases (mets). It is generally distinguished from cancer invasion, which is the ... The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a ...
The mixed-type is further classified as carcinoma with chondroid metaplasia, carcinoma with osseous metaplasia, and ... MCB was first recognized as a distinct pathological entity in 2000 by the World Health Organization. Owing to its relatively ... invasive ductal carcinoma with extensive squamous metaplasia, and invasive ductal carcinoma with pseudosarcomatous metaplasia. ... is a heterogeneous group of cancers that exhibit varied patterns of metaplasia and differentiation along multiple cell lines. ...
The medical significance of metaplasia is that in some sites where pathological irritation is present, cells may progress from ... If the stimulus causing metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. Metaplasia ... squamous metaplasia). Metaplasia is an adaptation that replaces one type of epithelium with another that is more likely to be ... Metaplasia (Greek: "change in form") is the transformation of one differentiated cell type to another differentiated cell type ...
The pathological findings of the process and etiopathogenetic and clinical observations have been reviewed by Cozzutto and ... possible myofibroblast metaplasia. A reactive fibrohistiocytic lesion simulating fibrous histiocytoma has been reported by ...
Women in the younger group mostly have inverted nipples due to squamous metaplasia that lines the ducts more extensively ... and a pathological investigation such as a biopsy may be necessary to exclude malignant mastitis. Although no causal relation ... is a frequently aseptic inflammation and has been associated with squamous metaplasia of the lactiferous ducts. The duct ...
The exposed columnar epithelium can undergo physiological metaplasia and change to tougher metaplastic squamous epithelium in ... which are considered physiological rather than pathological. Both gland openings and Nabothian cysts are helpful to identify ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... When it occurs as a result of disease or loss of trophic support due to other disease, it is termed pathological atrophy, ...
Not all middle ear epidermal cysts are congenital, as they can be acquired either by metaplasia of the middle ear mucosa or by ... are usually caused by pathological alteration of the ear drum leading to accumulation of keratin within the middle ear. ... Cholesteatoma may also arise as a result of metaplasia of the middle ear mucosa or implantation following trauma. Cholesteatoma ...
C) Carcinoma with osseous metaplasia: osseous metaplasia (blue arrow) is recognized in conventional CRC as foci of bone ... and a pathological TNM (pTNM) classification is performed after surgery. The most common metastasis sites for colorectal cancer ...
Adenocarcinoma of the stomach and intestinal metaplasia. H&E stain. If cancer cells are found in the tissue sample, the next ... Pathological and Therapeutic Aspects. Elsevier. pp. 215-220. ISBN 978-0-12-374135-6. Venturi, Sebastiano (2011). "Evolutionary ... Tsukamoto T, Mizoshita T, Tatematsu M (2006). "Gastric-and-intestinal mixed-type intestinal metaplasia: aberrant expression of ... and intestinal metaplasia. To find the cause of symptoms, the doctor asks about the patient's medical history, does a physical ...
... pathological staging - patient-controlled analgesia - Patient derived tumor xenografts - PCA - PDQ - peau d'orange - PEG- ... agnogenic myeloid metaplasia - agonist - agranulocytosis - AJCC staging system - alanine aminopeptidase - alanine transferase ... myelosclerosis with myeloid metaplasia - myelosuppression - myelosuppressive therapy - myometrium N-acetylcysteine - N- ... metaplasia - metaplastic carcinoma - metastasectomy - metastasis - metastasize - metastatic - metastatic cancer - ...
Significant production in any other organ is usually the result of a pathological process. When red blood cell (RBC) numbers ... splenic filtration and the pathogenesis of extramedullary hematopoiesis in agnogenic myeloid metaplasia". Hematologic Pathology ... On the other hand, hepatic EMH in adults can indicate a pathological state. This includes transplantation, hepatic tumors, ...
In 1897, he was appointed prosector at the Institute of Pathological Anatomy of University of Copenhagen. He was promoted to ... They concluded that Fibiger probably had mistaken metaplasia (a non-cancerous tumour) with malignant neoplasia (true cancer). ... While working at the Institute of Pathological Anatomy of University of Copenhagen, Fibiger discovered new roundworms in 1907 ...
... goblet cell metaplasia, and epithelial cell hypertrophy in the membranes of the respiratory system. Animal model and human ... CysLTR1 appears to be critical in mediating many of the pathological responses to CysLTs in humans. Montelukast, Zafirlukast, ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... hyperplasia can also occur as a pathological response, if an excess of hormone or growth factor is responsible for the stimuli ...
Intestinal metaplasia is classified histologically as complete or incomplete. With complete metaplasia, gastric mucosa is ... Gyula, Mozsik (16 January 2013). "Chapter 1: Diagnosis of Gastritis - Review from Early Pathological Evaluation to Present Day ... Intestinal metaplasia typically begins in response to chronic mucosal injury in the antrum and may extend to the body. Gastric ... Mucous gland metaplasia, the reversible replacement of differentiated cells, occurs in the setting of severe damage of the ...
Comprehensive Handbook of Iodine: Nutritional, Biochemical, Pathological and Therapeutic Aspects. Elsevier. pp. 215-220. ISBN ... Tsukamoto T, Mizoshita T, Tatematsu M; Mizoshita; Tatematsu (2006). "Gastric-and-intestinal mixed-type intestinal metaplasia: ... it associates intestinal metaplasia in neighbouring mucosa. Depending on glandular architecture, cellular pleomorphism and ...
Interleukin-13 has a critical role in the Goblet cell metaplasia. Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is ... Izuhara K, Arima K, Yasunaga S (2003). "IL-4 and IL-13: their pathological roles in allergic diseases and their potential in ... goblet cell metaplasia, mucus hypersecretion and airway remodelling which all contribute to airway obstruction. murine studies ...
... has a possible role in the development of well differentiated adenocarcinoma from intestinal metaplasia. The enzyme ... influence of aging and pathological states". Neuroscience Letters. 240 (3): 135-8. doi:10.1016/S0304-3940(97)00946-4. PMID ...
... and concluded that the tumours induced by the nematode in rats were metaplasia, not cancer. All tumours were due to vitamin A ... while working as Director of the Institute of Pathological Anatomy at the University of Copenhagen, dissected some wild rats ...
... process of aging rather than a result of an apparent pathological process.[citation needed] They are known to increase in ... chondroid metaplasia, and calcification. Again, in surgical planning, age-related degeneration of thinning and disorientation ...
... also metabolizes polyunsaturated fatty acids into signaling molecules that have physiological as well as pathological ... "Mutagenic activation of environmental carcinogens by microsomes of gastric mucosa with intestinal metaplasia". Cancer Research ...
... , in which cell maturation and differentiation are delayed, can be contrasted with metaplasia, in which cells of one ... Dysplasia is characterised by four major pathological microscopic changes: *Anisocytosis (cells of unequal size) ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... In the opposite situation-where the absence of the secondary color is pathological-is illustrated by an assay used to ...
An Unusual Tumor With Distinctive Clinical And Pathological Features". American Journal of Medicine. 38 (2): 241-56. doi: ... from early hyperplasia and metaplasia, through dysplasia, to the development of frank carcinoma - in a process similar to that ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... Payne-James, Jason; Busuttil, Anthony; Smock, William S. (eds.) (2003). Forensic Medicine: Clinical and Pathological Aspects. ...
... which are considered physiological rather than pathological.[16]:411 Both gland openings and Nabothian cysts are helpful to ... 411 The exposed columnar epithelium can undergo physiological metaplasia and change to tougher metaplastic squamous epithelium ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... a stage in the history of a pathological condition that begins with anatomical or physiological changes that are sufficient to ... Classical classification of human disease derives from observational correlation between pathological analysis and clinical ...
The cells which constitute the tumor eventually undergo metaplasia, followed by dysplasia then anaplasia, resulting in a ... The newly pathological sites, then, are metastases (mets).[3][4] It is generally distinguished from cancer invasion, which is ...
... "pathological" (e.g., pathological gambling or pathological liar). ... Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... The crossover between molecular pathology and epidemiology is represented by a related field "molecular pathological ... "pathological anatomy" or "morbid anatomy". However, pathology as a formal area of specialty was not fully developed until the ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... Pathological conditions are characterized by inadequate secretion of cytokines. Nitric oxide (NO) and reactive oxygen species ( ... Recent cytological data indicates that necrotic death occurs not only during pathological events but it is also a component of ... current researchers have demonstrated that the occurrence of necrotic cell death can not only occur during pathological ...
Izuhara K, Arima K, Yasunaga S (2003). "IL-4 and IL-13: their pathological roles in allergic diseases and their potential in ... IL-13 je odgovoran za mnoge osobine alergijskih plućnih bolesti, uključujući metaplasia goblet ćelija i mukozna hipersekrecija ...
Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ... Many proteins shown to be highly upregulated in pathological states by immunohistochemistry are potential targets for therapies ...
A new physiological phenomenon of Desired Metaplasia for regeneration of tissues and organs in vivo. Annals of NYAS 1998. Bynum ... Antonio Benivieni Pathological anatomy 1493-1541 - Paracelsus On the relationship between medicine and surgery surgery book ...
The pathological diagnosis was consistent with chronic hematocele. Current research is ongoing for proper diagnosis and helping ... and calcified tunica sac which may also show osseous metaplasia. Hematoceles can be a challenge to diagnose since they can ...
Clinico-pathological Correlation of Lens Epithelial Metaplasia and Late. Spontaneous in the bag Intraocular Lens Dislocation ... Clinico-pathological Correlation of Lens Epithelial Metaplasia and Late Spontaneous in the bag Intraocular Lens Dislocation ... Clinico-pathological Correlation of Lens Epithelial Metaplasia and Late. Spontaneous in the bag Intraocular Lens Dislocation ... There was evidence of sub-capsular metaplasia.. Conclusions : In the 1970s, Scott demonstrated profound changes in the lens ...
"Intraocular osseous metaplasia. A clinico-pathological study". Indian J Ophthalmol. 50 (3): 183-8. PMID 12355691.CS1 maint: ... a clinico-pathological correlation of a rare disease and review of literature". Clin Ophthalmol. 6: 2049-57. doi:10.2147/OPTH. ... clinico-pathological profiles, management and outcomes". J Cancer Res Ther. 10 (2): 294-8. doi:10.4103/0973-1482.136570. PMID ...
Pathological Conditions, Anatomical. Metaplasia. Pathologic Processes. Carotid Artery Diseases. Cerebrovascular Disorders. ...
Agnogenic Myeloid Metaplasia) ... Clinical and pathological criteria for the diagnosis of ...
Induction of mucous cell metaplasia by tumor necrosis factor alpha in rat middle ear: The pathological basis for mucin ... title = "Induction of mucous cell metaplasia by tumor necrosis factor alpha in rat middle ear: The pathological basis for mucin ... Induction of mucous cell metaplasia by tumor necrosis factor alpha in rat middle ear: The pathological basis for mucin ... Induction of mucous cell metaplasia by tumor necrosis factor alpha in rat middle ear : The pathological basis for mucin ...
... are specific for long and short segments of Barretts oesophagus but their use has not been assessed in intestinal metaplasia ... Results were correlated with clinical, endoscopic, and pathological data. RESULTS: Sixty (23.6%) of our patients presenting ... and intestinal metaplasia (p,0.02). CONCLUSION: In patients presenting with intestinal metaplasia in normal appearing GOJ, the ... Intestinal metaplasia of the GOJ was typed by histochemistry with high iron diamine-alcian blue staining and by ...
The relative risk of pathological lung cytology was higher in chemical refining than in mechanical refining and tanning.. ... Pulmonary cytology specimens were normal or showed cellular atypical metaplasia. No cases with atypical cells or obvious ...
No agreed-on system is both available and prospectively shown to provide reliable estimates of the underlying pathological ... Intestinal metaplasia was missed in more than 50% of those with confirmed intestinal metaplasia. No set or site of biopsy ... Current and future studies that use the Sydney System as basis for detecting intestinal metaplasia are not likely to be ... Forty-six patients were studied, 20 with H pylori infection and 36 with intestinal metaplasia. Using either version of the ...
In addition, 1 or 2 other associated photographs, such as radiological or pathological images, can be submitted. A brief ... Osseous Metaplasia in a Juvenile Rectal Polyp. Haynes, Harry R.*; Wiskin, Anthony E.†; Basude, Dharam†; Gradhand, Elise‡ ...
This is the condition behind the pathological lesions found in the bladder wall, ureter and renal; and also tumour, both benign ... Infections are characterized by pronounced acute inflammation, squamous metaplasia, blood and reactive epithelial changes. ... Under normal situation, the eggs released into the bladder do not cause pathological symptoms. But eggs often fail to penetrate ... When eggs are released, they sometimes become permanently stuck in the bladder and cause pathological symptoms. The eggs are ...
A typical metaplasia involves a somewhat disorderly metaplastic epithelium. The pathological growth of activated lymphoid cells ... Metaplasia is a form of controlled cell growth in which one type of fully differentiated cell substitutes for another type of ... In one specific embodiment, the target cells exhibit pathological growth or proliferation. As used herein, the term " ... Metaplasia can occur in epithelial or connective tissue cells. ... susceptible to or at risk of developing pathological growth of ...
this can either be physiological or pathological. BUT not all reduced cell mass is due to atrophy, it can also be related to ... what is metaplasia? transformation of one differentiated cell type into another eg. transdifferentiation of stem cells ...
A typical metaplasia involves a somewhat disorderly metaplastic epithelium. [0087] The pathological growth of activated ... Metaplasia is a form of controlled cell growth in which one type of fully differentiated cell substitutes for another type of ... 0073] In one specific embodiment, the target cells exhibit pathological growth or proliferation. As used herein, the term " ... Metaplasia can occur in epithelial or connective tissue cells. ... susceptible to or at risk of developing pathological growth of ...
The medical significance of metaplasia is that in some sites where pathological irritation is present, cells may progress from ... If the stimulus causing metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. Metaplasia ... squamous metaplasia). Metaplasia is an adaptation that replaces one type of epithelium with another that is more likely to be ... Metaplasia Squamous. Glandular. Cell death. Necrosis Coagulative necrosis. Liquefactive necrosis. Gangrenous necrosis. Caseous ...
When could you find pathological hyperplasia?. endometriosis, psoriasis, liver regeneration. What is metaplasia?. A change/ ... Why would you find metaplasia?. Persistent injury/irritation (smoker) What conditions could produce metaplasia?. Barret ... hyperplasia, metaplasia, dysplasia. What are the 3 categories of cellular accumulations?. 1. Normal cellular constituent 2. An ... 1. Atrophy 2. Hypertrophy 3. Hyperplasia 4. Metaplasia 5. Dysplasia. What is atrophy?. An adaptation to diminished need or ...
In pathological samples, neutrophils were considered as absent (score 0) when there was none or only single sporadic cells per ... a) Morphological aspect of colonic carcinoma with areas of squamous metaplasia. (b) The same section stained with anti-DAO ... This is the first description of polyamines expression in dog colonic mucosa in normal and in different pathological conditions ... In immunohistochemical essays, the number of immunoreactive cells for each antibody observed in normal or pathological colonic ...
Dysplasia vs Metaplasia. Dysplasia comes from the root Greek term meaning bad formation. It is a pathological term used to ... Difference Between Dysplasia and Metaplasia. • Categorized under Health , Difference Between Dysplasia and Metaplasia ... Often in pathological tests, a condition of Dysplasia where the growth and differentiation of cells are delayed are compared ... On the other hand, the transformation from one cell type to another in Metaplasia is often the result of the initiation caused ...
Necrosis is associated with being pathological - Apoptosis can be physiological or pathological - Apoptosis is a neat process ... What is metaplasia and give an example? A reversible change in which one adult cell type is replaced by anotherm. E.g. ... Necrosis is associated with being pathological - Apoptosis can be physiological or pathological - Apoptosis is a neater process ... Apoptosis may be physiological but necrosis is only pathological. - Apoptosis is an active energy dependent process - Apoptosis ...
As mentioned above, HE and Masson staining pathological section of lung tissue in model groups showed a progressive process of ... There is an agreement that chronic inflammation is important for damage and metaplasia of the respiratory epithelium [9]. ... Figure 3: The effect of SB on histological analysis revealed typical pathological features by Masson staining. Pictures ... Collectively, our data demonstrated that SB could ameliorate the typical pathological features of COPD, airway remodeling. ...
There were 11 (12.8%) patients that had pathological evidence of Barretts esophagitis. All patients had Barretts metaplasia ... Lastly, further research should focus on the true clinical implications of the findings of Barretts metaplasia in this patient ... Any suspicious areas of the esophagus were biopsied and sent for pathological examination. ...
Barretts esophagus, high-grade dysplasia, and early adenocarcinoma: a pathological study. Am J Gastroenterol1997;92:586-91. ... 11 This mucosa is considered an incomplete form of intestinal metaplasia, similar to type II and type III intestinal metaplasia ... which show the characteristic incomplete intestinal metaplasia (also called "specialised" mucosa).1 Intestinal metaplasia is ... which resembles incomplete intestinal metaplasia in the stomach. These similarities with incomplete intestinal metaplasia are ...
Metaplasia occurs as an adaptive change; dysplasis and anaplasia are connected to malignant changes.. Cell damage for any ... exists in some conditions in which pathological changes occur but no clinical signs are evident (often communicable during ... Metaplasia. replacement of one cell type with another e.g. adaptive mechanism providing more resistant tissue - stratified ... increase in CELL NUMBER -either compensatory or pathological -NOT A CANCER but risk of cancer may increase. ...
... bronchial metaplasia; and, in some cases, squamous metaplasia. There were cholesterol clefts and increased numbers of ... Pathological changes were maximal after 18-24 months at 3,500 or 7,000 μg·m−3 exposure levels. Microscopic findings were: ... Pathological and histological findings in the lung after DEPs exposure have mostly been studied in rats and include increases ... DE alone did not induce pathological changes 64. Other studies carried out with higher doses of DEPs (300 μg) under similar ...
Pathological Conditions, Anatomical. Heart Valve Diseases. Heart Diseases. Cardiovascular Diseases. Ventricular Outflow ...
The initial treatment with a female animal used for dry eye . Squamous metaplasia of the drug. Pathological see pathological ...
See for detailed pathological scoring criteria. Statistical testing could not be performed in groups containing only zero ... and acinar to ductal metaplasia (arrows). (E) Quantification of metaplastic changes determined by a trained pathologist shows ... See for detailed pathological scoring criteria. Statistical testing could not be performed in groups containing only zero ... absence of metaplasia in control mice. However, 9 out of 13 mice treated with cerulein for 6 months show metaplastic changes. ...
Osteoid metaplasia is a rare event. We report one such case of RCC with massive osteoid metaplasia in a 62 year old lady. The ... The pathological diagnosis which should be considered include metastatic carcinoma, adrenal myelolipoma, extraskeletal ... Osseus metaplasia have also been reported in other tumors most commonly in colon. 7The mechanism of ossification in tumors is ... Osteoid metaplasia has been suggested to be a marker for favourable prognosis because there are typically no tumour invasion ...
PLGC is a group of diseases with pathological features of intestinal metaplasia or dysplasia based on chronic atrophic ... C) Pathological changes of gastric tissue of in different groups of rats (H&E: 100×). *p , 0.05 compared with the normal group ... Atrophic glands, intestinal metaplasia and lymphocyte infiltration were shown in the model group, and compared with the model ... In chronic atrophic gastritis patients with or without intestinal metaplasia, pepsinogen I often decreased (Terasawa et al., ...
Under pathological conditions, however, more significant changes begin to occur in the differentiation of tissue cells. These ... changes are known as metaplasia.. General histology studies histogenesis during formation of tissues in embryonic development, ... The problems indicated above are directly connected with the behavior of cells and tissues under pathological conditions, such ... the structure and nutrition of pathologically altered organs and of the histological bases for the development of pathological ...
Transdifferentiation and metaplasia as a paradigm for understanding development and disease. Cell. Mol. Life Sci. 65:33-40. ... Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced. Am. J. Kidney Dis. 26:678- ... Metaplasia is the conversion of one differentiated cell type into another, as observed in experimental tissue remodeling and ... random pathological tissue specimens, where it occurs spontaneously. Metaplasia is something cell biologists now call ...
  • Cytokeratin immunoreactivity of intestinal metaplasia at normal oesophagogastric junction indicates its aetiology. (biomedsearch.com)
  • BACKGROUND AND AIMS: Cytokeratin (CK) 7 and 20 patterns are specific for long and short segments of Barrett's oesophagus but their use has not been assessed in intestinal metaplasia arising in macroscopically normal gastro-oesophageal junction (GOJ). (biomedsearch.com)
  • Intestinal metaplasia of the GOJ was typed by histochemistry with high iron diamine-alcian blue staining and by immunohistochemistry using CK7 and CK20 antibodies. (biomedsearch.com)
  • RESULTS: Sixty (23.6%) of our patients presenting with a normal GOJ had intestinal metaplasia. (biomedsearch.com)
  • CONCLUSION: In patients presenting with intestinal metaplasia in normal appearing GOJ, the cytokeratin pattern identifies two groups of patients, one with features identical to those of long segment Barrett's oesophagus and one with features seen in H pylori gastritis. (biomedsearch.com)
  • Evaluation of gastric mucosal biopsy site and number for identification of Helicobacter pylori or intestinal metaplasia: role of the Sydney System. (nih.gov)
  • Pathologists are frequently asked to evaluate gastric mucosal biopsy specimens for the presence of Helicobacter pylori infection and for potentially important changes such as intestinal metaplasia. (nih.gov)
  • Gastric biopsy specimens from patients who had multiple biopsies performed on predetermined sites were examined to compare the original and the revised Sydney Systems for the detection of intestinal metaplasia and H pylori. (nih.gov)
  • Forty-six patients were studied, 20 with H pylori infection and 36 with intestinal metaplasia. (nih.gov)
  • Both the original and the revised Sydney recommendations seriously underestimated the prevalence of intestinal metaplasia. (nih.gov)
  • Intestinal metaplasia was missed in more than 50% of those with confirmed intestinal metaplasia. (nih.gov)
  • No set or site of biopsy specimens was found that could reliably exclude the presence of intestinal metaplasia. (nih.gov)
  • Current and future studies that use the Sydney System as basis for detecting intestinal metaplasia are not likely to be reliable. (nih.gov)
  • Likewise, using the Sydney System to test posttherapy or with time will not accurately reflect the true status of intestinal metaplasia. (nih.gov)
  • It is detected on endoscopy and confirmed histologically by the presence in the lower oesophagus of a metaplastic mucosa, the so-called specialised epithelium, which resembles incomplete intestinal metaplasia in the stomach. (bmj.com)
  • These similarities with incomplete intestinal metaplasia are present on histology, mucin histochemistry, and immunohistochemistry with various differentiation markers (cytokeratins and MUC antigens). (bmj.com)
  • The diagnosis of Barrett's oesophagus is made on endoscopy, but it has to be confirmed by the histological examination of biopsies, which show the characteristic incomplete intestinal metaplasia (also called "specialised" mucosa). (bmj.com)
  • 1 Intestinal metaplasia is present in all cases in adults if sufficient sampling over a prolonged timescale is carried out. (bmj.com)
  • The significance of intestinal metaplasia discovered on biopsies taken from an endoscopically normal junction (sometimes considered as an "ultrashort" Barrett's oesophagus) remains controversial, and will not be discussed in this text. (bmj.com)
  • Histological examination of the resected specimen revealed a body type gastric mucosa in the submucosa, adjacent to which were extensive pyloric gland and intestinal metaplasia with mild to moderate dysplasia. (bmj.com)
  • To the best of our knowledge, this is the first report of a clinicopathological presentation of heterotopic gastric mucosa, pyloric gland type, and intestinal metaplasia with dysplastic changes in the gall bladder. (bmj.com)
  • 7-17 Pseudopyloric or pyloric gland metaplastic epithelium in the gall bladder is most common, being found in 66-84% of cholecystectomy specimens, 11 while intestinal metaplastic epithelium has been reported in 12-52% of gall bladders and is frequently associated with pyloric metaplasia. (bmj.com)
  • 11 Heterotopic gastric mucosa, as well as intestinal metaplasia in the gall bladder, may be one of the causes of gall bladder cancer. (bmj.com)
  • In the first case, the asymptomatic presence of heterotopic gastric mucosa, together with pyloric gland and intestinal metaplasia followed by dysplasia, occurred at the same time as colon adenocarcinoma. (bmj.com)
  • In close proximity to this heterotopic mucosa, extensive pyloric gland and intestinal metaplasia (fig 1 A, B) together with mild to focally moderate dysplastic changes in the metaplastic epithelium were observed (fig 2 A-C). In the remaining mucosa, typical features of chronic cholecystitis were obvious. (bmj.com)
  • These results suggested that the PWPC could reverse the intestinal metaplasia through improving the gastric cAMP, DNA and strengthening the cellular immunity and the effect would be enhanced when the treatment was based on syndrome differentiation. (nih.gov)
  • Helicobacter pylori infection, salt intake, smoking, alcohol, family history of gastric cancer, atrophic gastritis and intestinal metaplasia are established risk factors of gastric cancer. (scirp.org)
  • Results: Intestinal metaplasia was observed in 67.38% of patients. (scirp.org)
  • Conclusion: Intestinal metaplasia was the most histopathological phenotype among endoscopically diagnosed atrophic gastritis patients. (scirp.org)
  • Atrophic gastritis with the development of deeper inflammation, loss of parietal and chief cells and occasionally intestinal metaplasia. (doctorslounge.com)
  • Gastric atrophy with little evidence of inflammation but with thinning of the mucosa, loss of gastric glands and intestinal metaplasia which may be premalignant. (doctorslounge.com)
  • Development of intestinal metaplasia and, later, dysplasia. (sb.by)
  • Methods and results: Eighty consecutive patients with a GEJ carcinoma (43 from mainland China, and 37 from the USA) were evaluated for association with Barrett oesophagus (BO), chronic Helicobacter pylori gastritis, intestinal metaplasia, and outcome. (harvard.edu)
  • In contrast, GEJ cancers from American patients showed a strong association with distal oesophageal location, BO, and associated intestinal metaplasia and dysplasia. (harvard.edu)
  • Intestinal- type and diffuse-type cancer is different in clinical pathological features and gene expression profiling. (icgc.org)
  • Precancerous lesion including intestinal metaplasia (IM) and dysplasia (Dys) has high incidence and have a high risk to be transformed to malignance. (icgc.org)
  • Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease. (semanticscholar.org)
  • 1 , 9 The current definition of BE requires both endoscopic documentation for the presence of glandular epithelial lining and the histological identification of specialized intestinal metaplasia with goblet cells in the esophagus, 10 the hallmark of BE. (spiedigitallibrary.org)
  • Both H. pylori eradication and as pirin use induce molecular alterations in the atrophic gastritis mucosa but not in the intestinal metaplasia. (kstudy.com)
  • Short Segment Barrett's Esophagus: Clinical and Histological Features, Associated Endoscopic Findings, and Association with Gastric Intestinal Metaplasia. (ebscohost.com)
  • Objectives: To prospectively determine the clinical features, associated esophageal endoscopic lesions, associated gastric intestinal metaplasia, and prevalence of dysplasia and adenocarcinoma of short segment Barrett's. (ebscohost.com)
  • Intestinal metaplasia of the bladder is an uncommon glandular proliferation. (biomedcentral.com)
  • We examined a large series of intestinal metaplasia for the clinicopathological features and discuss the significance of this lesion. (biomedcentral.com)
  • All cases of intestinal metaplasia diagnosed in our institution between 1990 and 2014 were retrospectively reviewed. (biomedcentral.com)
  • We identified 89 patients with intestinal metaplasia during this period. (biomedcentral.com)
  • The majority of intestinal metaplasias located on or near the trigone (67 cases). (biomedcentral.com)
  • The initial histologic findings had revealed intestinal metaplasia with severe dysplasia. (biomedcentral.com)
  • Although intestinal metaplasia can be treated effectively by transurethral resection in most cases, its potential malignancy need to be taken into consideration after the evidence of recurrences and its association with bladder adenocarcinoma. (biomedcentral.com)
  • Intestinal metaplasia (IM) of the bladder, characterized by the presence of intestinal type epithelium in the bladder, are glandular proliferation that most frequently occur on the bladder trigone [ 1 , 2 ]. (biomedcentral.com)
  • Gastric intestinal metaplasia (GIM) is a pre-cancerous condition and a pivotal step in the formation of gastric cancer (GC). (oncotarget.com)
  • Metaplasia is not synonymous with dysplasia , and is not considered to be an actual cancer. (wikipedia.org)
  • The medical significance of metaplasia is that in some sites where pathological irritation is present, cells may progress from metaplasia, to develop dysplasia, and then malignant neoplasia (cancer). (wikipedia.org)
  • Dysplasia basically comprises of four distinct stages of pathological change. (differencebetween.net)
  • Often in pathological tests, a condition of Dysplasia where the growth and differentiation of cells are delayed are compared with Metaplasia where a mature cell of a distinct kind is replaced by another mature cell of yet another distinguished type. (differencebetween.net)
  • 3 Parallel to the metaplasia-dysplasia-adenocarcinoma sequence, numerous studies have demonstrated the accumulation of genetic abnormalities in cells, from normal cells to invasive malignant cells. (bmj.com)
  • All patients had Barrett's metaplasia and no patients had dysplasia. (sages.org)
  • All biopsy specimens were assessed for the presence of inflammation, atrophic gastritis, metaplasia and/or dysplasia. (scirp.org)
  • Eighty bronchial lesions were recorded at baseline, including 31 metaplasia, 12 mild dysplasia, 9 moderate dysplasia, 9 severe dysplasia, and 19 CISs. (aacrjournals.org)
  • Also, whether a low-grade lesion like metaplasia or mD progresses more slowly to lung cancer than high-grade dysplasia (MD and SD) is unknown. (aacrjournals.org)
  • Barrett's Esophagus, High-Grade Dysplasia, and Early Adenocarcinoma: A Pathological Study. (ebscohost.com)
  • What causes pathological atrophy? (studystack.com)
  • These responses include hyperplasia, hypertrophy, atrophy and metaplasia (Figure1). (hormones.gr)
  • Chronic gastritis can lead to three histological conditions: deep gastritis, gastric atrophy or metaplasia. (nethealthbook.com)
  • Pathological findings in patients treated with Tamoxifen include endometrial atrophy and fibro-cystic endometrial polyps, sometimes with cellular metaplasias. (thieme-connect.com)
  • The factors that stimulate mucous cell metaplasia-hyperplasia and mucin hyperproduction are poorly understood. (umn.edu)
  • These findings suggest that TNF-α is important in the development of mucous cell metaplasia-hyperplasia. (umn.edu)
  • This study demonstrated that inoculation of TNF-α into the middle ear cavity followed by eustachian tube obstruction stimulated mucous cell metaplasia-hyperplasia in the middle ear cleft, accompanied by abundant mucin or mucin-like glycoproteins in the middle ear effusion - a phenotype of MOM in humans. (umn.edu)
  • This finding suggests that TNF-α plays a key role in the pathogenesis of MOM through induction of mucous cell metaplasia-hyperplasia and mucin production. (umn.edu)
  • When could you find pathological hyperplasia? (studystack.com)
  • The aim of this study is to determine whether Paneth cell hyperplasia or metaplasia characteristically occurs in the colons of children with newly diagnosed idiopathic inflammatory bowel disease (IBD). (biomedcentral.com)
  • Further histopathological examination of the anterior lens capsule demonstrated replacement of the capsule by a thick layer of fibrous tissue with histological evidence of metaplasia of anterior lens epithelium. (arvojournals.org)
  • Since metaplasia is a key histological characteristic in patients with atrophic gastritis, it has been recommended to use the word "metaplastic" in both variants of atrophic gastritis: autoimmune metaplastic atrophic gastritis (AMAG) and environmental metaplastic atrophic gastritis. (dovepress.com)
  • We considered morphological changes of disease as they are compared with histological diagnosis of the pathological specimen, as well as control samples of normal esophagus, proximal stomach, and small intestine tissue. (spiedigitallibrary.org)
  • This is the first description of polyamines expression in dog colonic mucosa in normal and in different pathological conditions, suggesting that the balance between polyamine degradation and biosynthesis is evidently disengaged during neoplasia. (hindawi.com)
  • One example of pathological irritation is cigarette smoke, which causes the mucus-secreting ciliated pseudostratified columnar respiratory epithelial cells that line the airways to be replaced by stratified squamous epithelium, or a stone in the bile duct that causes the replacement of the secretory columnar epithelium with stratified squamous epithelium ( squamous metaplasia ). (wikipedia.org)
  • Squamous metaplasia of the drug. (cadasb.org)
  • I had squamous metaplasia chronic cervici w/ +hpv last yr. (healthtap.com)
  • I had squamous metaplasia+postive hpv last yr on my pap. (healthtap.com)
  • Last yr it was squamous metaplasia. (healthtap.com)
  • Squamous metaplasia is simply the replacement of one normal squamous cell with another by pathological definition. (healthtap.com)
  • In contrast, noncontrollers exhibited several alterations including condyloma acuminate, squamous metaplasia and acute colitis. (eurekaselect.com)
  • All the samples except two, showed pathological changes like a decrease in nuclear size, increase in cytoplasm, change in nucleus-cytoplasm ratio, a significant decrease in goblet cell density and certain degree of squamous metaplasia. (isciii.es)
  • One month following LASIK we observed histopathologic changes in the perilimbal conjunctiva, mainly a decrease in the number of goblet cells and different grades of squamous metaplasia. (isciii.es)
  • 3 Osseous metaplasia may occur secondary to ischemia, necrosis or inflammation in the tumor or surrounding tissues. (ispub.com)
  • The pathological hallmarks of chronic obstructive pulmonary disease (COPD) are inflammation of the small airways (bronchiolitis) and destruction of lung parenchyma (emphysema). (ersjournals.com)
  • Furthermore, if the level of K-Ras activity exceeds a threshold at which it begins to generate its own activators, then a feed-forward loop is formed between K-Ras activity and inflammation and pathological processes including oncogenesis are initiated. (ijbs.com)
  • It is a benign (i.e. non-cancerous) change that occurs as a response to change of milieu (physiological metaplasia) or chronic physical or chemical irritation. (wikipedia.org)
  • One hundred and forty-three patients were diagnosed as chronic superficial atrophic gastritis of gastric antrum or with metaplasia by means of gastroscopic observation with pathological biopsy examination. (nih.gov)
  • Primary pathological results were chronic bronchiolitis, emphysema and pavement epithelium metaplasia and were related to heavy cigarette smoking. (cdc.gov)
  • Metaplasia of urinary bladder induced by chronic irritation or infection can lead to adenocarcinoma. (radiopaedia.org)
  • Overall, GEJ carcinomas from Chinese patients revealed significantly more frequent location in the proximal stomach, higher pathological stage, larger size, younger patient age, and association with chronic H. pylori gastritis. (harvard.edu)
  • However, unlike mice with null mutations in any of the components in the gp130 signaling pathway, gp130 ΔSTAT mice also displayed gastrointestinal ulceration and a severe joint disease with features of chronic synovitis, cartilaginous metaplasia, and degradation of the articular cartilage. (rupress.org)
  • It may be possible to decide whether the pathological condition that endangered the well being of the fetus was an acute or a chronic process. (bmj.com)
  • Aims: To compare the clinical and pathological features of gastro-oesophageal junction (GEJ) carcinomas in Chinese and American patients. (harvard.edu)
  • This course is intended to the understanding of the general principles, terminology, diagnostic procedures, and basic concepts of pathology and will introduce to the study of the structural, biochemical, and functional changes in cells, tissues, and organs that underlie disease and the various pathological processes and their importance in the basis of human disease will be studied. (uninsubria.it)
  • General Pathology (anatomica pathologica generalis) gives us basic knowledge about the pathological changes in the body due to a disease. (univet.hu)
  • Several clinical and pathological features were studied. (bmj.com)
  • Metaplasia is an adaptation that replaces one type of epithelium with another that is more likely to be able to withstand the stresses it is faced with. (wikipedia.org)
  • What is more, being exposed to proinflammatory agents frequently or for a long time may contribute to damage and metaplasia of the respiratory epithelium and exert angiogenic and antiangiogenic effects [ 7 , 8 ]. (hindawi.com)
  • Pleural histology showed occasional strips of columnar epithelium , with ciliated metaplasia on the surface of the pleura. (thefreedictionary.com)
  • Pathological examination revealed gastric adenomyoma, which was composed of cysts and glandular structures lined by cuboidal to columnar epithelium surrounded by hypertrophic smooth muscle bundles. (thefreedictionary.com)
  • Pathological assessment revealed hyperkeratosis, epidermal acanthosis and a well-circumscribed neoplastic tumor composed of papillary projection lined by columnar epithelium with decapitating secretion that was diagnostic for Hidradenoma papilliferum (Figure 2). (thefreedictionary.com)
  • Up-regulated PDX-1 expression is also observed in premalignant metaplastic ductal epithelium during transforming growth factor (TGF)-alpha-induced pancreatic ductal metaplasia and neoplasia. (atlasgeneticsoncology.org)
  • Little calcifications disseminated between tendinous fibers (N=2), voluminous ones encapsulated by a fibrous tissue (N=2) and in one sample an intra-tendinous osseous metaplasia. (bmj.com)
  • Finally, one sample had an osseous metaplasia within the tendon with Runx2 positive cells. (bmj.com)
  • 8 It has been suggested that RCC with calcification or bone tend to be hypovascular and that this may predispose the tumor to ischemia and subsequent metaplasia. (ispub.com)
  • As pathological calcification in cartilage can be associated with chondrocytes apoptosis, we sought for anti-Caspase III expression in the cells of the peripheral area. (bmj.com)
  • Pathological calcification. (univet.hu)
  • If the stimulus causing metaplasia is removed or ceases, tissues return to their normal pattern of differentiation. (wikipedia.org)
  • Micrograph of a gastro - esophageal junction with pancreatic acinar metaplasia . (wikipedia.org)
  • When cells are faced with physiological or pathological stresses, they respond by adapting in any of several ways, one of which is metaplasia. (wikipedia.org)
  • This stimulus can be physiological or pathological. (hormones.gr)
  • These include mucus metaplasia, and mesenchymal activation, the latter important in wound healing. (uvm.edu)
  • Pathological mucus production and pathological changes in the muco-substance. (univet.hu)
  • Pulmonary cytology specimens were normal or showed cellular atypical metaplasia. (ilo.org)
  • Molecular and cellular mechanisms involved in this pathological mineralization process are not clearly identified. (bmj.com)
  • Immunohistochemical staining for p120 ctn was performed on 96 tumor samples, 20 cases of Barretts metaplasia and 13 lymph node metastases. (ovid.com)
  • To study the biological significance of oxalates within the breast tumor microenvironment, we measured oxalate concentration in both human breast tumor tissues and adjoining non-pathological breast tissues. (biomedcentral.com)
  • We found that all tested breast tumor tissues contain a higher concentration of oxalates than their counterpart non-pathological breast tissue. (biomedcentral.com)
  • Cystitis cystica glandularis is essentially cystitis cystica that has undergone metaplasia to form glandular tissue. (ispub.com)
  • There were 11 (12.8%) patients that had pathological evidence of Barrett's esophagitis. (sages.org)
  • Four hundred and forty eight satisfactory specimens from 406 patients with adequate clinical and/or pathological follow up data were examined in the study period. (bmj.com)
  • In this study, we evaluated pathological alterations in GALT, trying to associate them with clinical parameters of HIV infected patients with or without evidence of viral control. (eurekaselect.com)
  • The available data in the literature (177 cases), two current clinical patients, and cases which occurred in The Netherlands (13) were reviewed concerning the clinical presentation, pathological features, radiological data, and treatment options of chondrosarcoma of the cranial base. (bmj.com)
  • Thus, at sites where abnormal metaplasia is detected, efforts are made to remove the causative irritant, thereby decreasing the risk of progression to malignancy . (wikipedia.org)
  • Abnormal pathological morbid complicated grief disorder, traumatic grief prigerson et al. (nationalautismcenter.org)
  • In addition, they both share the common features of endothelial metaplasia and the secretion of an abnormal Descemet's membrane as a pathological posterior collagenous layer (PCL) with a small or absent posterior non-banded zone. (bmj.com)
  • In our case series, subcapsular metaplasia of epithelial lens identified in these cases of in-the-bag IOL dislocation are strikingly similar to the pathological changes in the crystalline lens described above. (arvojournals.org)
  • The similarity in findings lends support to the hypothesis that zonular dehiscence and lens dislocation results from progressive capsular contraction secondary to RRD induced lens epithelial metaplasia. (arvojournals.org)
  • Lastly, further research should focus on the true clinical implications of the findings of Barrett's metaplasia in this patient population. (sages.org)
  • Each of them have characteristic pathological appearances under the microscope and they have certain clinical significance as I will briefly mention. (nethealthbook.com)
  • CONCLUSION--The presence and the particular distribution of active cathepsin B in OA cartilage at 'more involved' sites suggest a pathological role for this enzyme in sustaining and perpetuating cartilage degradation. (bmj.com)
  • 1 It is assumed that chondrosarcomas originate from remnants of embryonal cartilage or from metaplasia of meningeal fibroblasts. (bmj.com)
  • The sequence of development of pathological processes in the mucous membrane of the stomach - under the influence of adverse factors (in particular, helicobacter infection) is presented by the following stages (P. Correa, 1992г. (sb.by)
  • In addition, 1 or 2 other associated photographs, such as radiological or pathological images, can be submitted. (lww.com)
  • Conclusion: HIV-controllers exhibit lower pathological alterations in the gut tissue, associated with higher CD4 T cell count, and lower viral load. (eurekaselect.com)
  • Tissue metaplasia, with the presence of chondrocyte phenotype [ 5 ] and occasional fatty and bony deposits [ 2 , 4 , 5 ], is observed. (biomedcentral.com)
  • On the other hand, the transformation from one cell type to another in Metaplasia is often the result of the initiation caused by an unusual stimulus. (differencebetween.net)
  • The pathological diagnosis which should be considered include metastatic carcinoma, adrenal myelolipoma, extraskeletal osteosarcoma and angiomyelolipoma. (ispub.com)
  • Histopathology of these specimens confirmed cystitis cystica et glandularis with (globlet cell) metaplasia. (ispub.com)
  • The relative risk of pathological lung cytology was higher in chemical refining than in mechanical refining and tanning. (ilo.org)
  • Results were correlated with clinical, endoscopic, and pathological data. (biomedsearch.com)
  • A new pathological technology called "gastric mucosal sausage roll" was introduced. (oncotarget.com)
  • Adjacent von brunn nests with cystitis glandularislike metaplasia, most non-symmetrical data distributions have a concurrent papillary uro- thelial cells. (nationalautismcenter.org)
  • Previous published case reports have confirmed this pathological sequence of events. (ispub.com)
  • Patient characteristics, pathological features, and follow-up outcomes were obtained. (biomedcentral.com)
  • The pathogenesis of endometriosis is still mysterious, being retrograde menstruation and coelomic metaplasia the most accepted hypotheses. (springer.com)
  • Endometriosis is a pathological condition characterized by the the presence of endometrial glands and stroma outside of the uterine cavity. (springer.com)
  • A pathological examination revealed that the pericardial cavity was enlarged with a diameter of 60cm. (go.jp)
  • We are unraveling the molecular signals whereby JNK1 exerts this pathological role and with a company are testing JNK1 specific inhibitors as targets for airway remodeling. (uvm.edu)
  • In this review, we addressed this topic by reviewing the results of clinical investigations and molecular pathological analyses of the roles of H. pylori eradication and aspirin administration in the prevention of MGC. (kstudy.com)
  • Unfortunately, the molecular pathological analyses of these interventions have been limited by short follow-up periods. (kstudy.com)
  • While other stimuli may also be responsible for cathepsin B expression in OA chondrocytes, the similarity with artificially modulated cells indicates fibroblastic metaplasia as a plausible mechanism. (bmj.com)
  • Paneth cell metaplasia (PCM) is well described in adults but little is known about the distribution of colonic Paneth cells and the occurrence of PCM in a paediatric population. (biomedcentral.com)
  • The placenta is an easily available specimen and the costs of a routine pathological examination are moderate. (bmj.com)
  • Osseus metaplasia have also been reported in other tumors most commonly in colon. (ispub.com)
  • Loss of normal surface p120 ctn expression was found in 4/20 (20%) Barretts metaplasia, in 65/96 (68%) tumors, and 11/13 (85%) lymph node metastases. (ovid.com)