Paraplegia
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Spastic Paraplegia, Hereditary
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
Spinal Cord Ischemia
Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.
Spinal Cord Injuries
Tuberculosis, Spinal
Paraparesis
Aortic Aneurysm, Thoracic
Quadriplegia
Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.
Spinal Cord Compression
Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.
Laminectomy
A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.
Hysteria
Myelography
Thoracic Vertebrae
Muscle Spasticity
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
Spinal Cord
Aortography
Pedigree
Blood Vessel Prosthesis Implantation
Aneurysm, Dissecting
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Myelitis, Transverse
Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)
Arachnoiditis
Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)
Tabes Dorsalis
Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)
Paraparesis, Spastic
Cinnarizine
Aorta, Thoracic
Hematoma, Epidural, Spinal
Adaptor Protein Complex 4
Aortic Rupture
Genes, Dominant
Blood Vessel Prosthesis
Heart Bypass, Left
Decompression, Surgical
Cerebrospinal Fluid Pressure
Cellulose, Oxidized
Aortic Aneurysm, Abdominal
Adenosine Triphosphatases
Kyphosis
Reflex, Babinski
A reflex found in normal infants consisting of dorsiflexion of the HALLUX and abduction of the other TOES in response to cutaneous stimulation of the plantar surface of the FOOT. In adults, it is used as a diagnostic criterion, and if present is a NEUROLOGIC MANIFESTATION of dysfunction in the CENTRAL NERVOUS SYSTEM.
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Energy cost of propulsion in standard and ultralight wheelchairs in people with spinal cord injuries. (1/1047)
BACKGROUND AND PURPOSE: Wheelchair- and subject-related factors influence the efficiency of wheelchair propulsion. The purpose of this study was to compare wheelchair propulsion in ultralight and standard wheelchairs in people with different levels of spinal cord injury. SUBJECTS: Seventy-four subjects (mean age=26.2 years, SD=7.14, range=17-50) with spinal cord injury resulting in motor loss (30 with tetraplegia and 44 with paraplegia) were studied. METHOD: Each subject propelled standard and ultralight wheelchairs around an outdoor track at self-selected speeds, while data were collected at 4 predetermined intervals. Speed, distance traveled, and oxygen cost (VO2 mL/kg/m) were compared by wheelchair, group, and over time, using a Bonferroni correction. RESULTS: In the ultralight wheelchair, speed and distance traveled were greater for both subjects with paraplegia and subjects with tetraplegia, whereas VO2 was less only for subjects with paraplegia. Subjects with paraplegia propelled faster and farther than did subjects with tetraplegia. CONCLUSION AND DISCUSSION: The ultralight wheelchair improved the efficiency of propulsion in the tested subjects. Subjects with tetraplegia, especially at the C6 level, are limited in their ability to propel a wheelchair. (+info)Heart rate during exercise with leg vascular occlusion in spinal cord-injured humans. (2/1047)
Feed-forward and feedback mechanisms are both important for control of the heart rate response to muscular exercise, but their origin and relative importance remain inadequately understood. To evaluate whether humoral mechanisms are of importance, the heart rate response to electrically induced cycling was studied in participants with spinal cord injury (SCI) and compared with that elicited during volitional cycling in able-bodied persons (C). During voluntary exercise at an oxygen uptake of approximately 1 l/min, heart rate increased from 66 +/- 4 to 86 +/- 4 (SE) beats/min in seven C, and during electrically induced exercise at a similar oxygen uptake in SCI it increased from 73 +/- 3 to 110 +/- 8 beats/min. In contrast, blood pressure increased only in C (from 88 +/- 3 to 99 +/- 4 mmHg), confirming that, during exercise, blood pressure control is dominated by peripheral neural feedback mechanisms. With vascular occlusion of the legs, the exercise-induced increase in heart rate was reduced or even eliminated in the electrically stimulated SCI. For C, heart rate tended to be lower than during exercise with free circulation to the legs. Release of the cuff elevated heart rate only in SCI. These data suggest that humoral feedback is of importance for the heart rate response to exercise and especially so when influence from the central nervous system and peripheral neural feedback from the working muscles are impaired or eliminated during electrically induced exercise in individuals with SCI. (+info)Airway hyperresponsiveness to ultrasonically nebulized distilled water in subjects with tetraplegia. (3/1047)
The majority of otherwise healthy subjects with chronic cervical spinal cord injury (SCI) demonstrate airway hyperresponsiveness to aerosolized methacholine or histamine. The present study was performed to determine whether ultrasonically nebulized distilled water (UNDW) induces airway hyperresponsiveness and to further elucidate potential mechanisms in this population. Fifteen subjects with SCI, nine with tetraplegia (C4-7) and six with paraplegia (T9-L1), were initially exposed to UNDW for 30 s; spirometry was performed immediately and again 2 min after exposure. The challenge continued by progressively increasing exposure time until the forced expiratory volume in 1 s decreased 20% or more from baseline (PD20) or the maximal exposure time was reached. Five subjects responding to UNDW returned for a second challenge 30 min after inhalation of aerosolized ipratropium bromide (2.5 ml of a 0.6% solution). Eight of nine subjects with tetraplegia had significant bronchoconstrictor responses to UNDW (geometric mean PD20 = 7.76 +/- 7.67 ml), whereas none with paraplegia demonstrated a response (geometric mean PD20 = 24 ml). Five of the subjects with tetraplegia who initially responded to distilled water (geometric mean PD20 = 5.99 +/- 4.47 ml) were not responsive after pretreatment with ipratropium bromide (geometric mean PD20 = 24 ml). Findings that subjects with tetraplegia are hyperreactive to UNDW, a physicochemical agent, combined with previous observations of hyperreactivity to methacholine and histamine, suggest that overall airway hyperresponsiveness in these individuals is a nonspecific phenomenon similar to that observed in patients with asthma. The ability of ipratropium bromide to completely block UNDW-induced bronchoconstriction suggests that, in part, airway hyperresponsiveness in subjects with tetraplegia represents unopposed parasympathetic activity. (+info)Anaesthetic management of a woman who became paraplegic at 22 weeks' gestation after a spontaneous spinal cord haemorrhage secondary to a presumed arteriovenous malformation. (4/1047)
A 19-yr-old woman developed a paraplegia with a T10 sensory level at 22 weeks' gestation. The spinal injury was caused by spontaneous bleed of a presumed arteriovenous malformation in the spinal cord. She presented for Caesarean section at term because of the breech position of her fetus. The successful use of a combined spinal epidural-regional anaesthetic is described and the risks of general and regional anaesthesia are discussed. (+info)Occurrence of familial spastic paraplegia in only one of monozygous twins. (5/1047)
Three patients who suffer from spastic paraplegia are described who belong to two generations in one family. One of the patients, who has had symptoms and signs for at least 10 years, has a monozygous twin who is unaffected. Using blood groups and chromosomal polymorphisms, the probability of monozygosity is estimated to be 0.99986. The observation of nonpenetrance in familial spastic paraplegia suggests that environmental factors may be involved in provocation and emphasises the need for careful genetic counselling in this and related diseases. (+info)Neurotoxic effects of 2,5-hexanedione on normal and neurofilament-deficient quail. (6/1047)
The neurotoxic effects of 2,5-hexanedione (2,5-HD) were investigated using neurofilament (NF)-deficient (Quv) Japanese quail in comparison with normal Japanese quail. Both Quv and normal Japanese quail were inoculated intraperitoneally with 350 mg/kg/day 2,5-HD for 6 consecutive wk. The results of 2,5-HD exposure differed substantially between the 2 strains of Japanese quail. The 2,5-HD-exposed normal quail showed leg paralysis about 4 wk after initiation of dosing. Some treated normal quail fell into dysstasia and died of nutritional disturbances. Histologically, 2,5-HD-treated normal quail had NF-rich axonal swellings and degeneration in the distal parts of the peripheral nerves, spinal cord, and cerebellar peduncles. In contrast, 2,5-HD-injected Quv quail showed tonic convulsion, ataxia gait, severe quivering, and excitation about 2-3 days after administration. Some treated Quv birds died immediately after systemic tonic convulsion, probably because of asphyxia. Although all treated Quv quail showed neurologic signs, there were no recognizable 2,5-HD-induced lesions in the nervous system. After about 4-6 wk of dosing, 2,5-HD induced distal axonopathy in normal quail and acute neurotoxicity in Quv quail. (+info)Triplet pregnancy achieved through intracytoplasmic sperm injection with spermatozoa obtained by prostatic massage of a paraplegic patient: case report. (7/1047)
Spinal cord-injured men with ejaculation disorders can have children thanks to assisted reproduction techniques. Spermatozoa from these patients are usually obtained through vibratory stimulation, electroejaculation or by puncturing the seminal duct or the testicle. We present the first published case, as far as we are aware, of spermatozoa obtained through prostatic massage of a paraplegic patient. Penile vibratory stimulation was unsuccessful in this patient. In-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) with spermatozoa obtained through electroejaculation was performed at another centre but pregnancy was not achieved. Through prostatic massage, we obtained a total semen volume of 6 ml containing a total count of 12.32x10(6) spermatozoa (6.24x10(6) with tails), 8% of which had motility (graded + and ++); and 16% of which had normal morphology. The spermatozoa obtained were then used to perform IVF with ICSI and a triplet pregnancy was achieved. Prostatic massage appears to be an easy, non-traumatic and risk-free method to obtain spermatozoa from paraplegic patients. (+info)Pregnancy of the wife of a complete paraplegic by homologeous insemination after an intrathecal injection of neostigmine. (8/1047)
A case of successful pregnancy following artificial insemination following intrathecal neostigmine injection in the wife of a complete traumatic paraplegic (T7-T8 to T11-T12) is described. (+info)
Acute Paraplegia as a Presentation of Aortic Saddle Embolism
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Paraplegic rats walk and regain feeling after stem cell treatment - Science Bulletin
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Definition for paraplegic
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Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF...
paraplegia | Difference Between
Painful paraplegia: Definition with Painful paraplegia Pictures and Photos
Septuagenarian dies on Air Peace flight - Punch
Paraplegia | Doctors Hospital
View Tetraplegia Paraplegia A Guide For Physiotherapists 5Th Edition
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Basal ganglia symptoms and Focal seizure and Hyperreflexia and Paraplegia and Sudden onset of foot weakness exacerbated by...
Sudden Onset of Paraplegia: T2 and T3 Collapse with Abscess - Tuberculosis Case: How to Treat the Abscess
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Read a Superb Health Sample Essay on «How Paraplegia Affects the Lower Extremities» for Free at MarvelousEssay.org
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The New Family / 1,000 Families Project: Rocking the Chair with Robert Buren, a Dad Living with Paraplegia - The New Family
Therapy
Paraplegic person, labia is a little puffy on outside, swollen on inner side. What I could do to treat at home? - Doctors...
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Sports Participation by Paraplegics: Overview, History, Commonly Participated Sports
Sanjeevs Latest Blogs: Aug 11, 2011
Paraplegia (in SafetyLit)
Transient paraplegia after stent grafting of a descending thoracic aortic aneurysm treated with cerebrospinal fluid drainage<...
BlackBush Car Auction: California Paraplegia Lawyer, Southern California Paraplegia Attorney
Cerebral paraplegia | definition of cerebral paraplegia by Medical dictionary
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Hereditary spastic paraplegia (Version 1.217)
Traumatic Spinal Cord Injury Global Clinical Trials Review, H2, 2014 | news.sys-con.com
Oalib search
The feasibility of a brain-computer interface functional electrical stimulation system for the restoration of overground...
Linkage of pure autosomal recessive familial spastic paraplegia to chromosome 8 markers and evidence of genetic locus...
Hereditary Spastic Paraplegia
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Alteration of ornithine metabolism leads to dominant and recessive hereditary spastic paraplegia<...
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hereditary spastic paraplegia
Genetic and phenotypic characterization of complex hereditary spastic paraplegia
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Hereditary spastic paraplegia
Test | Invitae Hereditary Spastic Paraplegia Comprehensive Panel
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Paraplegia / Quadriplegia
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Paraplegia
Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid paralysis. The ... Paraplegia, or paraparesis, is an impairment in motor or sensory function of the lower extremities. The word comes from Ionic ... Individuals with paraplegia can range in their level of disability, requiring treatments to vary from case to case. ... The area of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. If four limbs ...
Hereditary spastic paraplegia
"Hereditary spastic paraplegia". nhs.uk. 2017-10-18. Retrieved 2018-01-28. Fink JK (2003). "The Hereditary Spastic Paraplegias ... GeneReviews/NCBI/NIH/UW entry on Spastic Paraplegia 3A GeneReviews/NCBI/NIH/UW entry on Hereditary Spastic Paraplegia Overview ... Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The ... In the United States, Hereditary Spastic Paraplegia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the ...
Spastic paraplegia 31
... is a rare type of hereditary spastic paraplegia which is characterized by sensation anomalies of the ... "Spastic paraplegia 31 - About the Disease - Genetic and Rare Diseases Information Center". rarediseases.info.nih.gov. Archived ... "Spastic paraplegia type 31: MedlinePlus Genetics". medlineplus.gov. Archived from the original on 2021-07-25. Retrieved 2022-07 ... Spasticity Hereditary spastic paraplegia Hereditary sensory and autonomic neuropathy RESERVED, INSERM US14-- ALL RIGHTS. " ...
Spastic paraplegia 6
... is a rare type of hereditary spastic paraplegia characterized by muscle tone and bladder anomalies ... "Spastic paraplegia 6". "Spastic paraplegia 6 - About the Disease - Genetic and Rare Diseases Information Center". rarediseases. ... "Genetic Testing - familial spastic paraplegia type 6 (Spastic paraplegia type 6 -SPG6-) - Gen NIPA1 . - IVAMI". www.ivami.com. ... People with spastic paraplegia 6 generally start showing symptoms during their late teenage years or early adulthood, the ...
List of people with paraplegia
Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid paralysis. Greg ... Paraplegia is an impairment in motor or sensory function of the lower extremities. The word comes from Ionic Greek (παραπληγίη ... The area of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. If four limbs ...
T52 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ...
Amputee sports classification
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Miller, Mark D.; Thompson, Stephen R. ( ...
S10 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ...
S7 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ...
Joan Scruton
Harris, Phillip (May 1994). "Miss Joan Scruton MBE". Paraplegia. 32 (5): 362-63. doi:10.1038/sc.1994.62. Hums, Mary (2010). " ...
Joë Bousquet
Ohry A, Ohry-Kossoy K. Joë Bousquet: paraplegia as a poet's plight and challenge. Paraplegia. 1988 Aug;26(4):273-7. Media ...
F3 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "UCI Cycling Regulations - Para cycling ...
T44 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Zettler, P. Is It Cheating to Use ...
S1 (classification)
Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). Deportistas sin Adjectivos (PDF) (in European ...
A3 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Dyer, B. An Insight into the Acceptable ...
T42 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Nolan, Lee; Patritti, Benjamin L.; Stana ...
F1 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "UCI Cycling Regulations - Para cycling ...
S3 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ...
A1 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Hassani, Hossein; Ghodsi, Mansi; Shadi, ...
F7 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. IWAS (20 March 2011). "IWF RULES FOR ...
Kookal Ramunni Krishnan
Paraplegia. 1986;24:138-147. Quality of life in patients with spinal cord injury-basic issues, assessment, and recommendations ...
A7 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "Guide to the Paralympic Games - Appendix ...
Anterior spinal artery syndrome
Foo, D; Rossier, AB (Feb 1983). "Anterior spinal artery syndrome and its natural history". Paraplegia. 21 (1): 1-10. doi: ... "Interventions for reversing delayed-onset postoperative paraplegia after thoracic aortic reconstruction". The Annals of ...
Giles Brindley
Sacral anterior root stimulators for bladder control in paraplegia. Paraplegia. 1982 Dec;20(6):365-81. Holland, Owen; Husbands ...
Pulmonary fibrosis
Paraplegia. 27 (4): 278-83. doi:10.1038/sc.1989.42. PMID 2780083. eMedicine Specialties > Pulmonology > Interstitial Lung ...
F57 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Hassani, Hossein; Ghodsi, Mansi; Shadi, ...
S4 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ...
T46 (classification)
Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). Deportistas sin Adjectivos (PDF) (in European ...
T45 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "PARALYMPIC TRACK & FIELD: Officials ...
S2 (classification)
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ...
Spastic paraplegia type 7: MedlinePlus Genetics
... is one of more than 80 genetic disorders known as hereditary spastic paraplegias. Explore symptoms, inheritance, genetics of ... Spastic paraplegia type 7 (also called SPG7) is one of more than 80 genetic disorders known as hereditary spastic paraplegias. ... Spastic paraplegia type 7 likely accounts for only a small percentage of all spastic paraplegia cases. ... Like all hereditary spastic paraplegias, spastic paraplegia type 7 involves spasticity of the leg muscles and some muscle ...
Hereditary Spastic Paraplegia: Practice Essentials, Etiology, Epidemiology
Hereditary spastic paraplegia (HSP) is not a single disease entity; it is a group of clinically and genetically diverse ... Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working Group. Neurology. 1996 Jun. ... encoded search term (Hereditary Spastic Paraplegia) and Hereditary Spastic Paraplegia What to Read Next on Medscape ... Hereditary Spastic Paraplegia. Updated: Jun 11, 2021 * Author: Nam-Jong Paik, MD, PhD; Chief Editor: Stephen Kishner, MD, MHA ...
Hereditary Spastic Paraplegia: Practice Essentials, Etiology, Epidemiology
Hereditary spastic paraplegia (HSP) is not a single disease entity; it is a group of clinically and genetically diverse ... Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working Group. Neurology. 1996 Jun. ... encoded search term (Hereditary Spastic Paraplegia) and Hereditary Spastic Paraplegia What to Read Next on Medscape ... Hereditary Spastic Paraplegia. Updated: Jun 11, 2021 * Author: Nam-Jong Paik, MD, PhD; Chief Editor: Stephen Kishner, MD, MHA ...
Statement by the International Medical Society of Paraplegia
Chemotherapy of Infected Urines in Paraplegia | The BMJ
Statement by the International Medical Society of Paraplegia
Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52
Autosomal recessive spastic paraplegia 52 is caused by biallelic mutations in AP4S1 which encodes a subunit of the adaptor ... Autosomal recessive spastic paraplegia 52 is caused by biallelic mutations in AP4S1 which encodes a subunit of the adaptor ... Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52 Ann Clin Transl Neurol. 2020 ...
paraplegia | Difference Between
Paraplegia | Winchester Hospital
Paraplegia. Definition. Paraplegia is a complete or partial loss of movement or feeling in the lower half of the body. ... Paraplegia happens when there is damage below the neck. The most common cause is trauma, such as from a sports injury or car ... Paraplegia is often due to accidents that cannot be prevented.. Resources Christopher and Dana Reeve Foundation. http://www. ...
Spastic Paraplegia Foundation Kicks-Off Annual Rare Disease Awareness Week
The Spastic Paraplegia Foundation announces the 3rd Annual 5K Run, Walk & Roll as the kick-off event for the #HSPandPLS ... The Spastic Paraplegia Foundation is a world leader, dedicated to medical research in finding cures and treatments for, motor ... Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS). We are a 501(c)3 nonprofit Tax ID#: 04-3594491.. # ... Spastic Paraplegia Foundation. 1605 Goularte Place, Fremont, CA 94539-7241 Phone: 877-773-4483 Website: http://sp-foundation. ...
Clinical features of hereditary spastic paraplegia due to spastin mutation | Neurology
HSP : HSP & PLS : Spastic Paraplegia Foundation
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Search of: 'fatty acid hydroxylase-associated neurodegeneration' OR 'neurodegeneration with brain iron accumulation' OR ...
Hereditary Spastic Paraplegia Australian Support Group - Genetic Support Network Victoria (GSNV)
A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia - Mayo Clinic
Complete paraplegia resulting from surfer's myelopathy
All three patients were novice surfers and had a typical clinical course of onset: rapid progression of paraplegia after back ... Complete paraplegia resulting from surfers myelopathy Am J Phys Med Rehabil. 2013 Sep;92(9):833-7. doi: 10.1097/PHM. ... All three patients were novice surfers and had a typical clinical course of onset: rapid progression of paraplegia after back ... Despite months of rehabilitation at our hospital, in all three patients, complete paraplegia (T9-T12) and bladder-bowel ...
paraplegia Archives - Diane Chamberlain
Clinical case: Patient with spinal cord stimulation who suffered post-surgical paraplegia and cerebrospinal fluid leak, the...
Original electronic design to perform epimysial and neural stimulation in paraplegia - Inria - Institut national de recherche...
Paraplegia | Abraham, Watkins, Nichols, Agosto, Aziz & Stogner
Texas Paraplegia Attorneys. Handling Spinal Cord Injury Lawsuits in Texas and Throughout the Nation. Victims of negligent ... For a free initial consultation with a Houston paraplegia injury lawyer, call (713) 222-7211 (toll free 713-222-7211) or ... actions that cause paralyzing conditions such as paraplegia and quadriplegia face severe financial, physical and emotional ... including those involving paraplegia. 800-594-4884. Free case evaluation. ...
ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia - JPND
Paralysis, Paraplegia, Quadraplegia Lawyer | California Medical Malpractice Attorney | Medical Negligence
... paraplegia or quadraplegia, call medical malpractice attorney, Dr. Bruce Fagel, who can review medical records to deternine if ... Paralysis, Quadriplegia & Paraplegia. Free Case Evaluation. Paralysis is the inability to move a group of muscles as a result ... When this injury occurs in the spinal cord, the result is an inability to move either the legs alone (paraplegia) or both the ...
ZFIN Human Disease: hereditary spastic paraplegia 57
Metabolic cause of some spastic paraplegia - HSP Research Foundation
paraplegia Archives - Connecting Research
Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia<...
Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. JAMA Neurology. 2015 May 1;72(5):561-570. https ... Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. In: JAMA Neurology. 2015 ; Vol. 72, No. 5. pp. ... Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. Carlo Rinaldi, Thomas Schmidt, Alan J. Situ, ... Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia. / Rinaldi, Carlo; Schmidt, Thomas; Situ, Alan J. ...
Supplemental Guidance for Performing the Overseas Medical Examination of Refugees and Assisting Refugees with Significant...
Response to Postblock Epidural Hematoma Causing Paraplegia | Regional Anesthesia & Pain Medicine
Paraplegia following thoracic and lumbar transforaminal epidural steroid injections: how relevant is physician negligence? |...
Paraplegia following thoracic and lumbar transforaminal epidural steroid injections: how relevant is physician negligence? ... Paraplegia following thoracic and lumbar transforaminal epidural steroid injections: how relevant is physician negligence? ... Unfortunately, this traditional approach has been associated with paraplegia.1 Early cases created a knowledge void wherein ...
QuadriplegiaHereditary spastic paraplegiasThoracicSpastic Paraplegia FoundationSpasticityAmerican Spinal Injury AssociationAutosomal dominantGenesCongenitalLawyerSymptomsBowel and bladderDiagnosisGeneticsTetraplegiaLegsMutations2021OnsetInjuriesAffects2017TypeAccidentsDamagePathwaysCompleteAccidentLowerPatientsAffect
Quadriplegia5
- Victims of negligent actions that cause paralyzing conditions such as paraplegia and quadriplegia face severe financial, physical and emotional burdens. (abrahamwatkins.com)
- When this injury occurs in the spinal cord, the result is an inability to move either the legs alone (paraplegia) or both the arms and legs (quadriplegia). (fagellaw.com)
- Quadriplegia and paraplegia are typical results of spinal cord injuries. (abpersonalinjury.ca)
- The victims of spinal cord injuries causing paraplegia or quadriplegia, traumatic brain injuries , broken bones, or other catastrophic injuries often face considerable financial challenges. (klemickandgampel.com)
- Injuries to the lower part of the spinal cord may result in paraplegia, which is characterized by paralysis in the limbs and extremities below the waist, while injuries closer to the neck and brain stem may cause quadriplegia, or paralysis from the shoulders, down. (gcinjurylaw.com)
Hereditary spastic paraplegias10
- Spastic paraplegia type 7 (also called SPG7) is one of more than 80 genetic disorders known as hereditary spastic paraplegias. (medlineplus.gov)
- Signs and symptoms of hereditary spastic paraplegias are characterized by progressive muscle stiffness (spasticity) in the legs and difficulty walking. (medlineplus.gov)
- Hereditary spastic paraplegias are divided into two types: pure and complex. (medlineplus.gov)
- Like all hereditary spastic paraplegias, spastic paraplegia type 7 involves spasticity of the leg muscles and some muscle weakness. (medlineplus.gov)
- The prevalence of all hereditary spastic paraplegias combined is estimated to be 2 to 6 in 100,000 people worldwide. (medlineplus.gov)
- IMPORTANCE: The family of genes implicated in hereditary spastic paraplegias (HSPs) is quickly expanding, mostly owing to the widespread availability of next-generation DNA sequencing methods. (elsevier.com)
- Tesson C, Koht J, Stevanin G. Delving into the complexity of hereditary spastic paraplegias: how unexpected phenotypes and inheritance modes are revolutionizing their nosology. (medscape.com)
- Lallemant-Dudek P, Darios F, Durr A. Recent advances in understanding hereditary spastic paraplegias and emerging therapies. (medscape.com)
- Spastic paraplegia type 3A is one of a group of genetic disorders known as hereditary spastic paraplegias. (encyclopedia.pub)
- Spastic paraplegia type 3A belongs to a subgroup of hereditary spastic paraplegias known as autosomal dominant hereditary spastic paraplegia, which has an estimated prevalence of 2 to 9 per 100,000 individuals. (encyclopedia.pub)
Thoracic2
- Paraplegia following thoracic and lumbar transforaminal epidural steroid injections: how relevant is physician negligence? (bmj.com)
- 2 of them became permanent- ly paraplegic and 2 others who had severe thoracic vertebral fractures and paraplegia on first observation were transferred to other hospitals for treatment. (who.int)
Spastic Paraplegia Foundation2
- The Spastic Paraplegia Foundation announces the 3rd Annual 5K Run, Walk & Roll as the kick-off event for the #HSPandPLS Awareness Week. (prurgent.com)
- The Spastic Paraplegia Foundation is a world leader, dedicated to medical research in finding cures and treatments for, motor neuron diseases, Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS). (prurgent.com)
Spasticity5
- Welcome to the HSP Research Foundation - created in 2005 to find a cure for Hereditary Spastic Paraplegia - an inherited, degenerative disease affecting mainly the legs, causing muscle weakness, spasticity and severely impairing walking. (hspersunite.org.au)
- A rare form of hereditary spastic paraplegia which usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder disturbances and pes cavus. (rareendocrinologynews.com)
- These disorders are characterized by muscle stiffness (spasticity) and weakness in the lower limbs (paraplegia). (encyclopedia.pub)
- In addition to spasticity and weakness, which typically affect both legs equally, people with spastic paraplegia type 3A can also experience progressive muscle wasting (amyotrophy) in the lower limbs, reduced bladder control, an abnormal curvature of the spine (scoliosis), loss of sensation in the feet (peripheral neuropathy), or high arches of the feet (pes cavus). (encyclopedia.pub)
- A X-linked , clinical subtype of L1 syndrome , characterized by mild to moderate intellectual disability , delayed development of speech, hypotonia progressing to spasticity or spastic paraplegia, adducted thumbs, and mild to moderate distension of the cerebral ventricles. (rarerheumatologynews.com)
American Spinal Injury Association1
- AIM: To determine the effect of posterior vertebral column resection (PVCR) in patients with paraplegia by using the American Spinal Injury Association (ASIA) score and Scoliosis Research Society (SRS)-22 questionnaire. (ufuk.edu.tr)
Autosomal dominant2
- Spastic paraplegia type 3A accounts for 10 to 15 percent of all autosomal dominant hereditary spastic paraplegia cases. (encyclopedia.pub)
- Spastic paraplegia type 3A is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. (encyclopedia.pub)
Genes3
- Mackay-Sim A. Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery. (medscape.com)
- Mutationalspectrum of the SPG4 (SPAST) and SPG3A (ATL1) genes in Spanish patients withhereditary spastic paraplegia. (encyclopedia.pub)
- Hereditary spastic paraplegia AR, X-linked (NGS panel for 33 genes). (mendelian.co)
Congenital2
- This study aims at examining the body image of people with physical disabilities, specifically with non congenital paraplegia. (bvsalud.org)
- Two young males, aged between 20 and 25 years, both with five years of history of no congenital paraplegia took part in this study. (bvsalud.org)
Lawyer2
- For a free initial consultation with a Houston paraplegia injury lawyer, call (713) 222-7211 (toll free 713-222-7211 ) or contact our paralysis attorneys online . (abrahamwatkins.com)
- to speak with an experienced Pittsburgh-based paraplegia injury lawyer. (pribanic.com)
Symptoms4
- Nonfunctional m-AAA proteases cause a build-up of unusable proteins in the mitochondria of nerve cells, which can result in swelling of the cell, reduced cell signaling, and impaired cell movement, leading to the major signs and symptoms of spastic paraplegia type 7. (medlineplus.gov)
- This impaired nerve function leads to the signs and symptoms of spastic paraplegia type 3A. (encyclopedia.pub)
- Paraplegia is a dynamic condition where the patient can experience symptoms that vary over a period of time and change every day. (portea.com)
- In any case, through the right paraplegia diagnosis, it is possible to reverse or reduce paraplegia symptoms , and your doctor can help you during this challenging time. (portea.com)
Bowel and bladder2
- He had fall from height leads to sustain injury over lower dorsal spine with paraplegia and bowel and bladder involved. (nbsc.co.in)
- If these strands of nerves become compressed, a patient can suffer serious neurologic harm such as paraplegia or permanent loss of bowel and bladder function. (gislaw.com)
Diagnosis3
- which are the tests carried out to help in accurate paraplegia diagnosis? (portea.com)
- Balance Protection Insurance helps protect your finances if your earnings are interrupted by involuntary loss of employment, loss of self-employment, accidental dismemberment/paraplegia, disability or diagnosis of an insured critical illness or terminal illness or death. (collabriacreditcards.ca)
- Further, in the event of death, accidental dismemberment/paraplegia or diagnosis of an insured critical illness or terminal illness, the outstanding balance on your credit card account will be paid off (up to a maximum of $25,000). (collabriacreditcards.ca)
Genetics2
- " ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia" has been published in Neurology Genetics . (neurodegenerationresearch.eu)
- Group for the Study of the Genetics of Spastic Paraplegia. (encyclopedia.pub)
Tetraplegia2
- Individuals aged 60 years at the time of injury have a life expectancy of approximately 7.7 years (patients with high tetraplegia), 9.9 years (patients with low tetraplegia), and 12.8 years (patients with paraplegia). (onteenstoday.com)
- Additionally, paralysis caused by a spinal cord injury might be referred to as tetraplegia or paraplegia, depending on the areas that are affected. (cantorinjurylaw.com)
Legs3
- Extreme forms of paraplegia leave the injured person unable to walk or move his or her legs at all. (pribanic.com)
- Since paraplegia is a problem related to the brain or the spinal cord, most patients have perfectly normal legs. (portea.com)
- Paraplegia - which generally affects areas such as the legs and some of the abdominal area. (deutschmannlaw.com)
Mutations2
- Mutations in the SPG7 gene cause spastic paraplegia type 7. (medlineplus.gov)
- Autosomal recessive spastic paraplegia 52 is caused by biallelic mutations in AP4S1 which encodes a subunit of the adaptor protein complex 4 (AP-4). (nih.gov)
20211
- Awareness Week, held August 22-28, 2021, is an annual fundraiser to fund medical research and raise awareness for two progressive neurological diseases - Hereditary Spastic Paraplegia (HSP) and Primary Lateral Sclerosis (PLS). (prurgent.com)
Onset1
- All three patients were novice surfers and had a typical clinical course of onset: rapid progression of paraplegia after back pain while taking surfing lessons. (nih.gov)
Injuries2
Affects2
- Monoplegia affects one part of the body, whereas paraplegia impacts the body from the waist down. (atlinjurylawgroup.com)
- When the injury impacts a person neurologically and affects limb and body movements, complete paraplegia is said to have occurred. (portea.com)
20171
- Hereditary spastic paraplegia from 1880 to 2017: an historical review. (medscape.com)
Type6
- Spastic paraplegia type 7 can occur in either the pure or complex form. (medlineplus.gov)
- Spastic paraplegia type 7 likely accounts for only a small percentage of all spastic paraplegia cases. (medlineplus.gov)
- Spastic paraplegia type 3A is usually a pure hereditary spastic paraplegia, although a few complex cases have been reported. (encyclopedia.pub)
- Autosomal recessive spastic paraplegia type 18 (SPG18) is a rare, complex type of hereditary spastic paraplegia characterized by progressive spastic paraplegia (presenting in early childhood) associated with delayed motor development, severe intellectual disability and joint contractures. (mendelian.co)
- Autosomal Recessive Spastic Paraplegia Type 18 Is also known as spg18, intellectual disability, motor dysfunction, and joint contractures, idmdc. (mendelian.co)
- En raison de la gravité de ce type de traumatismes, notamment chez les jeunes, des efforts efficaces de prévention peuvent être nécessaires. (who.int)
Accidents1
- Paraplegia is often due to accidents that cannot be prevented. (winchesterhospital.org)
Damage1
- Paraplegia happens when there is damage below the neck. (winchesterhospital.org)
Pathways1
- Blackstone C. Cellular pathways of hereditary spastic paraplegia. (encyclopedia.pub)
Complete3
- Paraplegia is a complete or partial loss of movement or feeling in the lower half of the body. (winchesterhospital.org)
- Despite months of rehabilitation at our hospital, in all three patients, complete paraplegia (T9-T12) and bladder-bowel dysfunction remained. (nih.gov)
- There are two types of paraplegia, complete and incomplete. (portea.com)
Accident1
- I only narrowly escaped paraplegia after a traffic accident," said DTM boss Gerhard Berger. (worldsportsmania.com)
Lower3
- Paraplegia is an impairment in motor or sensory function of the lower extremities. (gamuts.net)
- The medical condition where the person experiences loss of feeling or movement in the lower half of the body is known as paraplegia. (portea.com)
- When paraplegia strikes, the brain or spinal cord is unable to send or receive signals to the lower half of the body. (portea.com)
Patients2
- Currently, no specific treatment exists to prevent, retard, or reverse progressive disability in patients with hereditary spastic paraplegia (HSP). (medscape.com)
- In addition to caring for patients, he described the role of the posterior column of the spinal cord in paraplegia, and he was among the first to describe the conditions of anorexia and of hypochondria. (asu.edu)
Affect1
- How does paraplegia affect someone's life? (onteenstoday.com)