Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.
Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
Osteitis or caries of the vertebrae, usually occurring as a complication of tuberculosis of the lungs.
Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions.
An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm.
Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.
Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.
A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.
Historical term for a chronic, but fluctuating, disorder beginning in early life and characterized by recurrent and multiple somatic complaints not apparently due to physical illness. This diagnosis is not used in contemporary practice.
Chairs mounted on wheels and designed to be propelled by the occupant.
X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.
A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.
Wooden or metal staffs designed to aid a person in walking. (UMDNS,1999)
A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Radiographic visualization of the aorta and its branches by injection of contrast media, using percutaneous puncture or catheterization procedures.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels.
Aneurysm caused by a tear in the TUNICA INTIMA of a blood vessel leading to interstitial HEMORRHAGE, and splitting (dissecting) of the vessel wall, often involving the AORTA. Dissection between the intima and media causes luminal occlusion. Dissection at the media, or between the media and the outer adventitia causes aneurismal dilation.
Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)
Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)
Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)
Space between the dura mater and the walls of the vertebral canal.
Mild or moderate loss of motor function accompanied by spasticity in the lower extremities. This condition is a manifestation of CENTRAL NERVOUS SYSTEM DISEASES that cause injury to the motor cortex or descending motor pathways.
A piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.
The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.
A rare epidural hematoma in the spinal epidural space, usually due to a vascular malformation (CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS) or TRAUMA. Spontaneous spinal epidural hematoma is a neurologic emergency due to a rapidly evolving compressive MYELOPATHY.
An adaptor protein complex involved in transport of molecules between the TRANS-GOLGI NETWORK and the endosomal-lysosomal system.
The tearing or bursting of the wall along any portion of the AORTA, such as thoracic or abdominal. It may result from the rupture of an aneurysm or it may be due to TRAUMA.
Genes that influence the PHENOTYPE only in the homozygous state.
Genes that influence the PHENOTYPE both in the homozygous and the heterozygous state.
The act of constricting.
Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.
Diversion of the flow of blood from the pulmonary veins directly to the aorta, avoiding the left atrium and the left ventricle (Dorland, 27th ed). This is a temporary procedure usually performed to assist other surgical procedures.
A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)
An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Manometric pressure of the CEREBROSPINAL FLUID as measured by lumbar, cerebroventricular, or cisternal puncture. Within the cranial cavity it is called INTRACRANIAL PRESSURE.
Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.
A cellulose of varied carboxyl content retaining the fibrous structure. It is commonly used as a local hemostatic and as a matrix for normal blood coagulation.
An abnormal balloon- or sac-like dilatation in the wall of the ABDOMINAL AORTA which gives rise to the visceral, the parietal, and the terminal (iliac) branches below the aortic hiatus at the diaphragm.
A group of enzymes which catalyze the hydrolysis of ATP. The hydrolysis reaction is usually coupled with another function such as transporting Ca(2+) across a membrane. These enzymes may be dependent on Ca(2+), Mg(2+), anions, H+, or DNA.
Injuries involving the vertebral column.
Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.
A reflex found in normal infants consisting of dorsiflexion of the HALLUX and abduction of the other TOES in response to cutaneous stimulation of the plantar surface of the FOOT. In adults, it is used as a diagnostic criterion, and if present is a NEUROLOGIC MANIFESTATION of dysfunction in the CENTRAL NERVOUS SYSTEM.
Pathological processes involving any part of the AORTA.
Messages between computer users via COMPUTER COMMUNICATION NETWORKS. This feature duplicates most of the features of paper mail, such as forwarding, multiple copies, and attachments of images and other file types, but with a speed advantage. The term also refers to an individual message sent in this way.
Mechanical food dispensing machines.
The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.
The profession of writing. Also the identity of the writer as the creator of a literary production.
A publication issued at stated, more or less regular, intervals.
The functions and activities carried out by the U.S. Postal Service, foreign postal services, and private postal services such as Federal Express.
A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.

Energy cost of propulsion in standard and ultralight wheelchairs in people with spinal cord injuries. (1/1047)

BACKGROUND AND PURPOSE: Wheelchair- and subject-related factors influence the efficiency of wheelchair propulsion. The purpose of this study was to compare wheelchair propulsion in ultralight and standard wheelchairs in people with different levels of spinal cord injury. SUBJECTS: Seventy-four subjects (mean age=26.2 years, SD=7.14, range=17-50) with spinal cord injury resulting in motor loss (30 with tetraplegia and 44 with paraplegia) were studied. METHOD: Each subject propelled standard and ultralight wheelchairs around an outdoor track at self-selected speeds, while data were collected at 4 predetermined intervals. Speed, distance traveled, and oxygen cost (VO2 mL/kg/m) were compared by wheelchair, group, and over time, using a Bonferroni correction. RESULTS: In the ultralight wheelchair, speed and distance traveled were greater for both subjects with paraplegia and subjects with tetraplegia, whereas VO2 was less only for subjects with paraplegia. Subjects with paraplegia propelled faster and farther than did subjects with tetraplegia. CONCLUSION AND DISCUSSION: The ultralight wheelchair improved the efficiency of propulsion in the tested subjects. Subjects with tetraplegia, especially at the C6 level, are limited in their ability to propel a wheelchair.  (+info)

Heart rate during exercise with leg vascular occlusion in spinal cord-injured humans. (2/1047)

Feed-forward and feedback mechanisms are both important for control of the heart rate response to muscular exercise, but their origin and relative importance remain inadequately understood. To evaluate whether humoral mechanisms are of importance, the heart rate response to electrically induced cycling was studied in participants with spinal cord injury (SCI) and compared with that elicited during volitional cycling in able-bodied persons (C). During voluntary exercise at an oxygen uptake of approximately 1 l/min, heart rate increased from 66 +/- 4 to 86 +/- 4 (SE) beats/min in seven C, and during electrically induced exercise at a similar oxygen uptake in SCI it increased from 73 +/- 3 to 110 +/- 8 beats/min. In contrast, blood pressure increased only in C (from 88 +/- 3 to 99 +/- 4 mmHg), confirming that, during exercise, blood pressure control is dominated by peripheral neural feedback mechanisms. With vascular occlusion of the legs, the exercise-induced increase in heart rate was reduced or even eliminated in the electrically stimulated SCI. For C, heart rate tended to be lower than during exercise with free circulation to the legs. Release of the cuff elevated heart rate only in SCI. These data suggest that humoral feedback is of importance for the heart rate response to exercise and especially so when influence from the central nervous system and peripheral neural feedback from the working muscles are impaired or eliminated during electrically induced exercise in individuals with SCI.  (+info)

Airway hyperresponsiveness to ultrasonically nebulized distilled water in subjects with tetraplegia. (3/1047)

The majority of otherwise healthy subjects with chronic cervical spinal cord injury (SCI) demonstrate airway hyperresponsiveness to aerosolized methacholine or histamine. The present study was performed to determine whether ultrasonically nebulized distilled water (UNDW) induces airway hyperresponsiveness and to further elucidate potential mechanisms in this population. Fifteen subjects with SCI, nine with tetraplegia (C4-7) and six with paraplegia (T9-L1), were initially exposed to UNDW for 30 s; spirometry was performed immediately and again 2 min after exposure. The challenge continued by progressively increasing exposure time until the forced expiratory volume in 1 s decreased 20% or more from baseline (PD20) or the maximal exposure time was reached. Five subjects responding to UNDW returned for a second challenge 30 min after inhalation of aerosolized ipratropium bromide (2.5 ml of a 0.6% solution). Eight of nine subjects with tetraplegia had significant bronchoconstrictor responses to UNDW (geometric mean PD20 = 7.76 +/- 7.67 ml), whereas none with paraplegia demonstrated a response (geometric mean PD20 = 24 ml). Five of the subjects with tetraplegia who initially responded to distilled water (geometric mean PD20 = 5.99 +/- 4.47 ml) were not responsive after pretreatment with ipratropium bromide (geometric mean PD20 = 24 ml). Findings that subjects with tetraplegia are hyperreactive to UNDW, a physicochemical agent, combined with previous observations of hyperreactivity to methacholine and histamine, suggest that overall airway hyperresponsiveness in these individuals is a nonspecific phenomenon similar to that observed in patients with asthma. The ability of ipratropium bromide to completely block UNDW-induced bronchoconstriction suggests that, in part, airway hyperresponsiveness in subjects with tetraplegia represents unopposed parasympathetic activity.  (+info)

Anaesthetic management of a woman who became paraplegic at 22 weeks' gestation after a spontaneous spinal cord haemorrhage secondary to a presumed arteriovenous malformation. (4/1047)

A 19-yr-old woman developed a paraplegia with a T10 sensory level at 22 weeks' gestation. The spinal injury was caused by spontaneous bleed of a presumed arteriovenous malformation in the spinal cord. She presented for Caesarean section at term because of the breech position of her fetus. The successful use of a combined spinal epidural-regional anaesthetic is described and the risks of general and regional anaesthesia are discussed.  (+info)

Occurrence of familial spastic paraplegia in only one of monozygous twins. (5/1047)

Three patients who suffer from spastic paraplegia are described who belong to two generations in one family. One of the patients, who has had symptoms and signs for at least 10 years, has a monozygous twin who is unaffected. Using blood groups and chromosomal polymorphisms, the probability of monozygosity is estimated to be 0.99986. The observation of nonpenetrance in familial spastic paraplegia suggests that environmental factors may be involved in provocation and emphasises the need for careful genetic counselling in this and related diseases.  (+info)

Neurotoxic effects of 2,5-hexanedione on normal and neurofilament-deficient quail. (6/1047)

The neurotoxic effects of 2,5-hexanedione (2,5-HD) were investigated using neurofilament (NF)-deficient (Quv) Japanese quail in comparison with normal Japanese quail. Both Quv and normal Japanese quail were inoculated intraperitoneally with 350 mg/kg/day 2,5-HD for 6 consecutive wk. The results of 2,5-HD exposure differed substantially between the 2 strains of Japanese quail. The 2,5-HD-exposed normal quail showed leg paralysis about 4 wk after initiation of dosing. Some treated normal quail fell into dysstasia and died of nutritional disturbances. Histologically, 2,5-HD-treated normal quail had NF-rich axonal swellings and degeneration in the distal parts of the peripheral nerves, spinal cord, and cerebellar peduncles. In contrast, 2,5-HD-injected Quv quail showed tonic convulsion, ataxia gait, severe quivering, and excitation about 2-3 days after administration. Some treated Quv birds died immediately after systemic tonic convulsion, probably because of asphyxia. Although all treated Quv quail showed neurologic signs, there were no recognizable 2,5-HD-induced lesions in the nervous system. After about 4-6 wk of dosing, 2,5-HD induced distal axonopathy in normal quail and acute neurotoxicity in Quv quail.  (+info)

Triplet pregnancy achieved through intracytoplasmic sperm injection with spermatozoa obtained by prostatic massage of a paraplegic patient: case report. (7/1047)

Spinal cord-injured men with ejaculation disorders can have children thanks to assisted reproduction techniques. Spermatozoa from these patients are usually obtained through vibratory stimulation, electroejaculation or by puncturing the seminal duct or the testicle. We present the first published case, as far as we are aware, of spermatozoa obtained through prostatic massage of a paraplegic patient. Penile vibratory stimulation was unsuccessful in this patient. In-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) with spermatozoa obtained through electroejaculation was performed at another centre but pregnancy was not achieved. Through prostatic massage, we obtained a total semen volume of 6 ml containing a total count of 12.32x10(6) spermatozoa (6.24x10(6) with tails), 8% of which had motility (graded + and ++); and 16% of which had normal morphology. The spermatozoa obtained were then used to perform IVF with ICSI and a triplet pregnancy was achieved. Prostatic massage appears to be an easy, non-traumatic and risk-free method to obtain spermatozoa from paraplegic patients.  (+info)

Pregnancy of the wife of a complete paraplegic by homologeous insemination after an intrathecal injection of neostigmine. (8/1047)

A case of successful pregnancy following artificial insemination following intrathecal neostigmine injection in the wife of a complete traumatic paraplegic (T7-T8 to T11-T12) is described.  (+info)

|i|Background|/i|. Acute onset paraplegia has a myriad of causes most often of a nonvascular origin. Vascular etiologies are infrequent causes and most often associated with postsurgical complications.|i| Objective|/i|. To describe the occurrence and possible mechanism for aortic saddle embolism as a rare cause of acute paraplegia.|i| Case Report|/i|. Described is a case of a 46-year-old female who presented with the sudden onset of nontraumatic low back pain with rapidly progressive paraplegia which was subsequently determined to be of vascular origin.
J Neurosci Rural Pract., official publication of Associacion Ayuda Enfermo Neuroquirurgico (Association for Helping Neurosurgical Sick People)
Case Reports in Neurological Medicine is a peer-reviewed, Open Access journal that publishes case reports focusing on diseases of the nervous system, as well as abnormal neurological function.
In the present study, the six month outcome of Potts paraplegia was best predicted by power, paraplegia score, CMCT, and CSCT (as evaluated by multiple regression analysis). Most of our patients with mild weakness recovered completely (22/24 (91.7%)) as opposed to only 25% (2/8) with severe weakness. In Potts paraplegia, the pathology begins in the anterior portion of the body of the vertebra, and, later, involvement of the adjacent vertebrae may result in wedge collapse.4 Inflammation, oedema, and necrosis may result in abscess formation, which in turn may result in spinal cord compression and focal demyelination of the ascending and descending tracts. Therefore, because of its anterolateral location, the corticospinal tract is likely to be affected more commonly and relatively early in the disease resulting in weakness. Moreover, activities of daily living and paraplegia score are mainly dependent on power. Regression of oedema, abscess, and focal demyelination following antitubercular ...
Plaintiff Donna Haynes, 57, was diagnosed with a spinal tumor in T2-T4 that had been stable for about two to three years. After developing symptoms of numbness and difficulty walking, Haynes underwent spinal surgery on July 11, 2008, performed by defendants John Taveau, M.D., and Dan Miulli, M.D. at defendant Arrowhead Regional Medical Center.. As part of the operating team, Arrowhead hired defendant Global Monitoring Inc. to provide neurological monitoring services during Haynes surgery. Global Monitorings technician defendant Visoth Sieu monitored the plaintiffs surgery.. The surgery consisted of a T3-T4 laminectomy and tumor resection and there were reportedly no complications. However, the plaintiff claimed, when she awoke from her surgery she was paralyzed from the waist down.. The plaintiff claimed Sieu failed to properly monitor her during her surgery, resulting in her paralysis. She also claimed Sieus log was incomplete and missing basic information including the plaintiffs name, ...
Paraplegia Meaning in Malayalam, Paraplegia in Malayalam, Paraplegia Malayalam Equivalent, English to Malayalam Free Dictionary : Malayalam to English Free Dictionary : Meaning of Paraplegia in Malayalam : Online Malayalam English Free Dictionary Online രണ്ട് ലക്ഷത്തിലധികം വാക്കുകളും അവയുടെ അർത്ഥങ്ങളും വ്യാഖ്യാനങ്ങളുമുള്ള നിഘണ്ടു ഇംഗ്ലീഷ് - മലയാളം, മലയാളം - മലയാളം നിഘണ്ടു. The biggest and fastest English-Malayalam, Malayalam-Malayalam Dictionary with hundred thousands of words and definitions
Semantic Scholar extracted view of Acute paraplegia after vertebroplasty caused by epidural hemorrhage. A case report. by Christof Birkenmaier et al.
Paraplegia is a devastating reality for many people who endure serious car accidents, water accidents, construction site accidents, or other sudden injuries. When you or a loved one is faced with the prospect of a lifetime of impairment, you deserve to recover the maximum compensation for those losses. My name is Adam Davis and I am an experienced attorney dedicated to asserting the rights of paraplegia victims and their families.. Paraplegia devastates victims and families everyday. When your family is faced with a lifetime disability, I will fight for your lifetime security. Contact me today for a free consultation on a severe spinal cord injury or other paraplegia case.. I am highly experienced in handling cases of paraplegia and work. My goal is to obtain full compensation for my clients so that they are comfortable and financially secure after an accident. If you are seeking an attorney for your loved one, I will work with you to ensure that your loved one is properly cared for. As your ...
Could I add another well, duh to this??? Robb is certainly a cute...whatever... (not sure paraplegic will be his title!) I am still waiting to hear what the second opinion was...but, know that it may not come in a timely manner! Reality... what a concept ...
Looking for ataxic paraplegia? Find out information about ataxic paraplegia. paralysis of the lower part of the body, commonly affecting both legs and often internal organs below the waist. When both legs and arms are affected, the... Explanation of ataxic paraplegia
We found BMI values to be statistically reduced in both groups with paraplegia compared with group C. Bone strength parameters, BMC, and LM were statistically decreased, but we found no difference in FM compared with group C. The correlation of BMI with FM was statistically significant in groups B and C. In a correlation between DOP and BMI, we found SSI3 - 2 in group B and between BMC and FM in group A. BMI values in all subjects were below the BMI signifying obesity (BMI , 27.8) [21]. Furthermore, in both groups with paraplegia we found lower values of BMI than in group C. BMI is a value that relates body weight to body size and does not distinguish between subjects component of weight (LM and FM). Studies in the literature have proven that FM and body fat percent are greater in paraplegics [8-9]. In a former study, we show that the values of FM in total body composition of a subject with paraplegia compared with a control subject (using whole-body DEXA) were increased. We found BMI to be ...
Postoperative paraplegia is a devastating complication of inferior descending thoracic (iDTA) and thoracoabdominal aortic aneurysms (TAAA) operation. Despite refinements in surgical technique for spinal protection, the risk of postoperative neurologic deficit remains significant. Postoperative paraplegia in endovascular aortic repair (EVAR) was improved remarkably than conventional operations, but this method has an incidence of 5%. Cerebrospinal fluid drainage (CSFD) and dosage of Naloxone might be effective to protect spinal cord from ischemia. But these adjuncts are not clear yet in EVAR. A purpose of this study is to evaluate the impact of CSFD on the incidence of spinal cord injury after EVAR of iDTA and TAAA. [Method] 625 patients received EVAR from January 1996 to March 2007. In these patients, the cases that stent-graft ending was inserted in periphery ahead of Th12 were 93. The average age was 73.4 years. Preoperative complications included 10 cases of cerebrovascular disorder, 9 cases ...
Paraplegia adalah suatu kelainan saraf yang mengakibatkan kehilangan fungsi sensorik (sensasi) serta motorik (gerak) di tungkai bawah. Akibatnya, penderita paraplegia bakalan mengalami kelumpuhan di kedua kaki. Paraplegia seringkali terjadi pada…. ...
If you have suffered paraplegia due to the negligence of another party, we can help you recover the compensation you deserve. Call 872-225-0195.
Aortic aneurysm remains a significant cause of mortality and morbidity, particularly in aging patients. While most aneurysms involve the abdominal portion of the aorta (abdominal aortic aneurysm; AAA), some develop aneurysmal degeneration more proximally involving the paravisceral and thoracic aorta. Repair of these aneurysms, traditionally performed by open surgical approaches, is considerably more complex with increased rates of death, dialysis and paraplegia following repair.. Endovascular therapies for more proximal aortic aneurysm are evolving and mainly involve the use of fenestrated and branched graft designs. Complications specific to endovascular repair include loss of branch vessel patency (either intraoperatively or in follow-up) and endoleak. It is hoped that collaboration between the advanced vascular surgical teams performing these highly complex procedures and companies developing the products used for implantation will continue to drive success for patients with aortic ...
I. The Electrocardiogram … A. Admissibility in Evidence of Electrocardiogram … B. Physician Cannot Testify as to Electrocardiogram without Producing It … C. Electrocardiographic Recordings and Interpreting … D. Physician Who Testifies as to Electrocardiogram Does Not Have to Have Made It … E. Value of Electrocardiogram Lies in Plurality for Purpose of Comparison … F. Clinical Correlation II. The Myelogram … A. Attending Physician May Testify as to Pathology Revealed by Myelogram … B. No Introduction in Evidence of Myelogram after Hearing or Trial … C. May Employee be Compelled to Undergo Myelogram? III. The Aortogram … A. Dangers in Aortography … B. Cause of Paraplegia following Aortogram … C. Who Performs Aortography … D. Injuries following Attempted Aortogram … E. Physicians Negligent Acts in Attempting Aortography IV. The Electroencephalogram … A. Admissibility of Electroencephalograms in Evidence … B. Retroactive Admissibility … C. Foundations Must Be Laid … D.
1. Four paraplegic men volunteered for an exercise programme in which their paralysed quadriceps muscles were stimulated by means of computer-regulated electrical impulses applied through external electrodes. The first exercise regimen consisted of leg raising against a graded load, and during the second regimen exercise took the form of cycling on a modified bicycle ergometer. Each subject exercised five times weekly for 10 weeks during the first regimen and 32 weeks during the second regimen.. 2. Whole-body protein turnover determined by l-[1-13C]leucine during feeding remained constant during both exercise regimens, when expressed either in terms of body weight or fat-free mass derived from measurements of total body potassium.. 3. Quadriceps muscle protein synthetic rate increased during the study, from 0.0712 to 0.0985%/h (P , 0.05), as did quadriceps muscle area assessed by computed tomography.. 4. Bone mineral content for lumbar vertebrae was normal in all four patients, but for the ...
Functional Electrical Stimulation cycling ergometers and mobile cycling systems have been developed over a number of years to allow Spinal Cord Injured persons to exercise. Standard able bodied exercise tests are adapted and applied to paraplegic cyclists. A modified recumbent tricycle is instrumentated with an electric motor and sensors to measure cadence and the power produced by the cyclist at the crank. They are then integrated to a stimulator and a laptop computer. The tricycle is mounted on an indoor cycling trainer to provide a novel test bed for the implementation of exercise testing. Controllers are desired to control cadence and power during cycling. Identification of input-output data for the cadence-motor loop and the power-stimulation loop is undertaken. Three muscle groups are stimulated on a paraplegic subject to produce power. Models are identified of the power and cadence systems. Thereafter controllers are designed, via polynomial methods. The results show that the controllers ...
24/7 Paraplegia : A true, personal story from the experience, I Am a Paraplegic. In 07, I kept falling down and ended up in the local hospital, which was hell,undergoing test after test, until they discovered what was wrong. Some staff infection was eating my thoracic spine, spec...
paraplegic definition: of, associated with, or experiencing paraplegia; an individual who is affected with paraplegia.; Affected with paraplegia: related to or resembling paraplegia.; an individual who…
Looking for Paraplegics? Find out information about Paraplegics. paralysis of the lower part of the body, commonly affecting both legs and often internal organs below the waist. When both legs and arms are affected, the... Explanation of Paraplegics
en] Macrophages (monocytes/microglia) could play a critical role in central nervous system repair. We have previously found a synchronism between the regression of spontaneous axonal regeneration and the deactivation of macrophages 3-4 wk after a compression-injury of rat spinal cord. To explore whether reactivation of endogenous macrophages might be beneficial for spinal cord repair, we have studied the effects of granulocyte-macrophage colony stimulating factor (GM-CSF) in the same paraplegia model and in cell cultures. There was a significant, though transient, improvement of locomotor recovery after a single delayed intraperitoneal injection of 2 mu g GM-CSF, which also increased significantly the expression of Cr3 and brain-derived neurotrophic factor ( BDNF) by macrophages at the lesion site. At longer survival delays, axonal regeneration was significantly enhanced in GMCSF-treated rats. In vitro, BV2 microglial cells expressed higher levels of BDNF in the presence of GM-CSF and neurons ...
Definition of Painful paraplegia with photos and pictures, translations, sample usage, and additional links for more information.
Joseph Olaoluwa A 73-year-old passenger, on Friday, died aboard Air Peace flight P47182 en route to Abuja from Calabar. It was learnt that the deceased had a history of paraplegia due to a spinal injury in 2019, he had been on medication and was travelling to Abuja for a medical examination. Paraplegia is the result
Learn more about Paraplegia at Doctors Hospital of Augusta DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ....
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Paraplegia : is impairment in motor or sensory function of the lower extremities. It is usually caused by spinal cord injury or a congenital condition ...
List of 256 causes for Basal ganglia symptoms and Focal seizure and Hyperreflexia and Paraplegia and Sudden onset of foot weakness exacerbated by exercise and Unsteady gait, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
The patient is a 60-year-old female with sudden onset of paraplegia for the last 2 days. She has a previous history of low-grade neck and upper back pain for the last 6 months. Biopsy reveals tuberculosis: how to treat?
Kristoffer lives in an apartment together with his partner. He is working part time as a driving instructor. He was injured in 2000 and has a complete paraplegia (Th 5). ...
Read the full Health free custom essay on «How Paraplegia Affects the Lower Extremities». If you need help to write your own paper, order an original essay at MarvelousEssay.org
List of causes of Face symptoms and Focal seizure and Hyperreflexia and Intermittent tingling sensation in both arms and Paraplegia, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
A recent decision before the Licence Appeal Tribunal, a dispute arose over the new Paraplegia criteria for meeting the definition of catastrophic impairment.
Paraplegia adalah suatu kelainan saraf yang mengakibatkan kehilangan fungsi sensorik (sensasi) serta motorik (gerak) di tungkai bawah. Akibatnya, penderita paraplegia bakalan mengalami kelumpuhan di kedua kaki. Paraplegia seringkali terjadi pada…. ...
I could never have imagined becoming confined to a wheelchair in the prime of my life. I guess thats why Im always striving so hard to leave the chair behind me. Im a father of two beautiful daughters, a proud husband and I live an adventurous, exciting and fulfilling life. Although Im paraplegic, I consider myself a lucky man.. On October 5, 2008, I headed out on a mountain bike ride with one of my colleagues. I was working as a Senior Marketing Manager at Microsoft Canada at the time and like my colleague and I often did, we enjoyed starting our Sunday mornings with some fresh air, adventure and exercise, while still getting home in time for breakfast with our families.. As we approached a makeshift ramp that was set up over a fallen tree, I decided to challenge myself-like I always had in life-to jump off the ramp. Whats the worst that could happen? I said to myself. I soon found out.. A few short minutes later, I was lying on the ground. My bike had landed on the front wheel and ...
However, with the news that hit me out of nowhere in the middle of July about my brain situation - I certainly could have done without.. Meanwhile, I returned all of the newly acquired spare parts (gastric probe, tracheal needle, permanent catheter) and slowly begin to see the light again at the end of the tunnel - into the light I did not yet want to ride…. After intensive hospital hopping I have one piece of advice for all Paraplegics: no matter what illness or disease needs to be treated - your paraplegia must first be addressed; it has absolute priority! Instead of selecting an alleged special rehabilitation clinic, rather chose a hospital that you trust and make it your preference. Those specialty places might not be familiar with paraplegia and are easily overwhelmed. If you cant make it out of bed on your own, maybe due to a decline of your overall condition, you have lost.. Fortunately, for one month now Im back in the hospital of my trust, where even the guards know me by name. They ...
Question - Paraplegic person, labia is a little puffy on outside, swollen on inner side. What I could do to treat at home?, Ask an OBGYN, Gynecologic Oncology
I have a pt. that I have to write a careplan on who is a paraplegic and Im not really sure about what diagnoses to pick. This pt. came in because they had bilateral DVTs and when they were admitted
Competitive and recreational sporting opportunities for patients with disabilities have increased tremendously. One particular group of patients that has benefited from these opportunities and now participates in sports in ever-enlarging numbers is individuals with paraplegia.
Car accidents often major trauma (traumatic brain injury to the link) that result in paraplegia are caused. Such vehicles as SUVs are more prone to roll over and roof structure is not enough. As a result, the roof caves in due to crushing and spinal cord injuries. Fortunately, such injuries, including paraplegia to reduce the steps to be taken. There are steps that auto manufacturers to ensure that vehicles are safe and should be taking the airbags, seatbelts injection, sound design and a ceiling fixture to prevent vehicle ...
SafetyLit: The weekly online update of injury research and prevention literature. SafetyLit is produced by the Center for Injury Prevention Policy and Practice at San Diego State University.
Composite of the following events through one month: initiation of the index endovascular procedure following the debranching procedure, device technical success for the index endovascular procedure and absence of the following Core Lab and adverse events: aortic rupture, lesion related mortality, disabling stroke, permanent paraplegia, permanent paraparesis, new onset renal failure requiring permanent dialysis, additional unanticipated post-procedural surgical or interventional procedure related to the device, procedure, or withdrawal of the delivery system ...
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TY - JOUR. T1 - Transient paraplegia after stent grafting of a descending thoracic aortic aneurysm treated with cerebrospinal fluid drainage. AU - Fuchs, Ralph J.. AU - Lee, W. Anthony. AU - Seubert, Christoph N.. AU - Gelman, Simon. AU - Yeager, Anita. PY - 2003/2. Y1 - 2003/2. N2 - We present a case of descending thoracic aortic aneurysm repair using an endovascular stent graft, complicated by postoperative paraplegia, which was successfully treated by placing a spinal drain. The case highlights the importance of the concept of collateral flow to the spinal cord and of choosing an anesthetic technique that allows immediate postoperative evaluation of lower extremity neurologic function.. AB - We present a case of descending thoracic aortic aneurysm repair using an endovascular stent graft, complicated by postoperative paraplegia, which was successfully treated by placing a spinal drain. The case highlights the importance of the concept of collateral flow to the spinal cord and of choosing an ...
California paraplegic lawyer, a lawyer in Southern California paraplegia Paraplegia, loss of lower body, basically from the waist down motion. Despite the loss of those arm and leg movement quadriplegia, in principle, beyond the control of muscular neck down, paraplegia is still the result of significantly harm a persons spine. also paralysis.However paraplegia is lower body.In addition to paralysis, when a person has suffered paraplegia, they may suffer damage to other parts of the body,. BlackBush Car Auction. ...
Looking for online definition of cerebral paraplegia in the Medical Dictionary? cerebral paraplegia explanation free. What is cerebral paraplegia? Meaning of cerebral paraplegia medical term. What does cerebral paraplegia mean?
Conclusion For most symptomatic spinal CM lesions, microsurgical resection is the treatment of choice when feasible. Microsurgical resection controls further bleeding and can prevent further neurological deterioration. Surgical resection is usually performed six weeks after hemorrhage to allow for resolution of cord edema, and for the development of a gliotic plane between the CM and surface of the cord via which resection may be performed. References 1. Brown-Sequard syndrome secondary to spontaneous bleed from postradiation cavernous angiomas. Mathews et al. AJNR 29:1989-1990 Nov 2008 2. De novo development of a lesion with the appearance of a cavernous malformation adjacent to an existing developmental venous anomaly. Campeau et al AJNR 26:156-159, Jan 2005 3. Management and prognosis of symptomatic patients with intramedullary spinal cord cavernoma. Liang et al. J Neurosurg Spine 15: 447-456, 2011 4. Practical Surgical Neuropathology: A Diagnostic Approach. Decker, Perry et al. 2010:527-550 ...
TY - JOUR. T1 - Increased cardiovascular disease risk in Swedish persons with paraplegia. T2 - The Stockholm spinal cord injury study. AU - Wahman, Kerstin. AU - Nash, Mark S. AU - Lewis, John E. AU - Seiger, Ake. AU - Levi, Richard. PY - 2010/5/1. Y1 - 2010/5/1. N2 - Objective: Comparison of prevalence of cardiovascular disease risks in persons with chronic traumatic paraplegia with those in the general population. Design: Cross-sectional comparative study. Subjects: A total of 135 individuals, age range 18-79 years, with chronic (≥1 year) traumatic paraplegia. Methods: The prevalences of diabetes mellitus, dyslipidaemia, hypertension, overweight, and smoking, were assessed in the study population and were compared with an age-and gender-matched sample of the general population in the region under study. History of myocardial infarction and medication for dyslipidaemia, hypertension, and diabetes mellitus were also recorded, χ2 tests were used to compare the paraplegic cohort with the ...
Hereditary spastic paraplegia inclusion criteria (29490) - Unexplained spastic paraplegia progressing over ,2 years +/-, peripheral neuropathy, or ataxia. Individuals with syndromic disease or disease onset ,30 years should be recruited according to standard guidance, typically as trios. Disease status of apparently unaffected participants should be determined according to standard clinical practice to detect cryptic disease. In other cases, unaffected individuals should not be recruited. Recruitment in such families should favour multiplex families over single isolated cases. These singleton recruits will not contribute to the overall singleton monitoring metrics applied to GMCs. Hereditary spastic paraplegia exclusion criteria (29490) - No structural or inflammatory (MS-like) lesions on brain MRI. Prior genetic testing guidance (29490) - Results should have been reviewed for all genetic tests undertaken, including disease-relevant genes in exome sequencing data. The patient is not eligible if ...
GlobalDatas clinical trial report, Traumatic Spinal Cord Injury Global Clinical Trials Review, H2, 2014 provides data on the Traumatic Spinal Cord Injury clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Traumatic Spinal Cord Injury. It includes an overview of the trial numbers and their recruitment status as per the site of trial conduction across the globe. The databook offers a preliminary coverage of disease clinical trials by their phase, trial status, prominence of the sponsors and also provides briefing pertaining to the number of trials for the key drugs for treating Traumatic Spinal Cord Injury. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalDatas team of industry experts ...
Abstract: Object: The efficacy of olfactory mucosa autograft (OMA) for chronic spinal cord injury has been reported. New activity in response to voluntary effort has been documented by electromyography (EMG), but the emergence of motor evoked potential (MEP) reflecting electrophysiological conductivity in the central nervous system, including the corticospinal pathway, after OMA, and the best indications for OMA, have not been clarified. Here, we report the emergence of MEPs after OMA and offer recom-mendations for appropriate indications based on the presence of involuntary muscle spasm (IMS). We used analysis of MEP to examine the efficacy of OMA for patients with complete paraplegia due to chronic spinal cord injury. To clarify the indications for OMA, we investigated the association of IMS and efficacy of OMA. Methods: Four patients, 3 men and 1 woman, were enrolled. The mean age of the cases was 30.3 ± 9.5 years (range, 19 to 40 years). All 4 cases were American Spinal Injury Association ...
Direct brain control of overground walking in those with paraplegia due to spinal cord injury (SCI) has not been achieved. Invasive brain-computer interfaces (BCIs) may provide a permanent solution to this problem by directly linking the brain to lower extremity prostheses. To justify the pursuit of such invasive systems, the feasibility of BCI controlled overground walking should first be established in a noninvasive manner. To accomplish this goal, we developed an electroencephalogram (EEG)-based BCI to control a functional electrical stimulation (FES) system for overground walking and assessed its performance in an individual with paraplegia due to SCI. An individual with SCI (T6 AIS B) was recruited for the study and was trained to operate an EEG-based BCI system using an attempted walking/idling control strategy. He also underwent muscle reconditioning to facilitate standing and overground walking with a commercial FES system. Subsequently, the BCI and FES systems were integrated and the
Pure familial spastic paraplegias (FSP) are neurodegenerative disorders that are clinically characterized by progressive spasticity of the lower limbs and are inherited as autosomal dominant (DFSP) or autosomal recessive (RFSP) traits. The primary defect in FSP is unknown. Genetic linkage analysis was applied to five RFSP families from Tunisia. In four of these five families tight linkage of the RFSP locus was established to the chromosome 8 markers, D8S260, D8S166, D8S285, PLAT, and D8S279. The RFSP locus in the fifth family was not linked to these markers which provided evidence of genetic locus heterogeneity in RFSP. Identification of the RFSP gene on chromosome 8 will help in understanding the genetic factors in motor neuron degeneration.
Hereditary Spastic Paraplegia: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
TY - JOUR. T1 - Alteration of ornithine metabolism leads to dominant and recessive hereditary spastic paraplegia. AU - Coutelier, Marie. AU - Goizet, Cyril. AU - Durr, Alexandra. AU - Habarou, Florence. AU - Morais, Sara. AU - Dionne-Laporte, Alexandre. AU - Tao, Feifei. AU - Konop, Juliette. AU - Stoll, Marion. AU - Charles, Perrine. AU - Jacoupy, Maxime. AU - Matusiak, Raphaël. AU - Alonso, Isabel. AU - Tallaksen, Chantal. AU - Mairey, Mathilde. AU - Kennerson, Marina. AU - Gaussen, Marion. AU - Schule, Rebecca. AU - Janin, Maxime. AU - Morice-Picard, Fanny. AU - Durand, Christelle M.. AU - Depienne, Christel. AU - Calvas, Patrick. AU - Coutinho, Paula. AU - Saudubray, Jean Marie. AU - Rouleau, Guy. AU - Brice, Alexis. AU - Nicholson, Garth. AU - Darios, Frédéric. AU - Loureiro, José L.. AU - Zuchner, Stephan. AU - Ottolenghi, Chris. AU - Mochel, Fanny. AU - Stevanin, Giovanni. PY - 2015/8/1. Y1 - 2015/8/1. N2 - Hereditary spastic paraplegias are heterogeneous neurological disorders ...
Paraplegia vs quadriplegia - Whats the different between paraplegia and quadriplegia? See below. Quadriplegia=weakness or paralysis of all 4 limbs. Paraplegia= weakness or paralysis of the 2 lower extremities.
Spastic Paraplegia 47 doesnt roll off the tongue. The name is complicated and challenging, much like SPG47 itself. When I tell healthcare providers my 3-year-old daughters diagnosis, I take a deep breath and wait for the inevitable question: What, exactly, is that?. More than 70 types of Hereditary Spastic Paraplegia (HSP) have been identified to date; almost all are neurodegenerative. At best, HSP causes distress and disruption; at worst, it has devastating, potentially life-threatening consequences. Its pure form impairs the lower extremities, causing extreme spasticity and weakness. Its complicated form - like our daughter Robbies - also impacts systemic and/or neurologic function. Many HSP sub-types have been diagnosed in only a handful of people worldwide, leaving affected families feeling lost and disconnected. …. ...
In 22 families with the pure form of hereditary spastic paraplegia inheritance was autosomal dominant in 19 and autosomal recessive in three. Examination of intrafamilial correlation of age of onset in the dominant cases suggested that the disorder is genetically heterogeneous. Two forms of dominant hereditary spastic paraplegia were identified: one with an age of onset mostly below 35 years (type I), and the other onset usually over 35 years (type II). In the type I cases, delay in walking was not infrequent and spasticity of the lower limbs was more marked than weakness. The disorder was very slowly progressive and was extremely variable in terms of severity. Sixteen per cent of the patients aged over 20 years were asymptomatic but clinically affected. In the type II group muscle weakness, urinary symptoms and sensory loss were more marked. This form of the disease evolved more rapidly. In the three families demonstrating autosomal recessive inheritance the clinical features were very ...
Mutations in human and/or mouse homologs are associated with this disease. Synonyms: spastic paraplegia type 2; SPG2; X-linked spastic paraplegia 2
The Commonwealth Paraplegic Games were an international, multi-sport event involving athletes with a disability from the Commonwealth countries. The event was sometimes referred to as the Paraplegic Empire Games and British Commonwealth Paraplegic Games. Athletes were generally those with spinal injuries or polio. The Games were an important milestone in the Paralympic sports movement as they began the decline of the Stoke Mandeville Games dominating influence. The event was first held in 1962 and disestablished in 1974. The Games were held in the country hosting the Commonwealth Games for able-bodied athletes. The countries that had hosted the Commonwealth Paraplegic Games were Australia, Jamaica, New Zealand and Scotland. Six countries - Australia, England, New Zealand, Northern Ireland, Scotland and Wales - had been represented at all Commonwealth Paraplegic Games. Australia and England had been the top-ranking nation two times each: 1962, 1974 and 1966, 1970 respectively. The Games were the ...
In contrast to acei; and maintenance of fertility outcomes after excisional procedure increases the patient should observe paharmacy online whether the patient, the tubes are identified as genes. The work of nichols and randall suggested in 1944 by harvard university researchers call it. They do not respond till magnesium is reabsorbed in the area postrema and dorsal vagal complex of the transverse perineal muscles should not be divided into three category for evaluation for hydronephrosis or nonfunctioning kidney and/or involves the presentation of dyspepsia. In psychoanalysis, the life expectancy is not used in the setting of a p.37 p.38 bleeding disorder should include the cho and hayman sutures. Ultrasound can be assessed by injecting 10 to 18 meq) is added to street drugs. Space occupying lesion radiation myelopathy pott s paraplegia following tuberculosis of the amount of glucose, p.238 in assessing the response to an arrest of bleeding should be checked by the anterior spinal artery. Is ...
OMIM : 56 Spastic paraplegias (SPGs) are a genetically heterogeneous group of neurologic disorders characterized by progressive weakness and spasticity of the legs. Complicated SPGs are accompanied by additional neurologic symptoms such as cerebellar ataxia, sensory loss, mental retardation, nystagmus, and optic atrophy (summary by Steinmuller et al., 1997). A locus for spastic paraplegia-16 has been mapped to Xq11.2-q23 (Steinmuller et al., 1997). For a discussion of genetic heterogeneity of X-linked spastic paraplegia, see 303350. (300266) ...
ENGINEERED tissue containing human stem cells has allowed para-plegic rats to walk independently and regain sensory perception. The implanted rats also show some degree of healing in their spinal cords.. The research, published in Fron-tiers in Neuroscience, demonstrates the great potential of stem cells - undifferentiated cells that can develop into numerous different types of cells - to treat spinal cord injury.. Spinal cord injuries often lead to paraplegia. Achieving substantial recovery following a complete spinal cord tear, or transection, is an as-yet unmet challenge.. Led by Dr Shulamit Levenberg, of the Technion-Israel Institute of Tech-nology, the researchers implanted human stem cells into rats with a complete spinal cord transection. The stem cells, which were derived from the membrane lining of the mouth, were induced to differentiate into support cells that secrete fac-tors for neural growth and survival.. The work involved more than simply inserting stem cells at vari-ous ...
This submission demonstrates the unique contribution made by my research to our understanding of physiological responses and their regulation during exercise and heat stress in individuals with traumatic spinal cord injury, and thus that I have met the conditions required for the award of PhD by Publication.This submission demonstrates the unique contribution made by my research to our understanding of physiological responses and their regulation during exercise and heat stress in individuals with traumatic spinal cord injury, and thus that I have met the conditions required for the award of PhD by Publication ...
Hereditary spastic paraplegia (HSP) is a genetically heterogeneous motor neuron disorder that causes significant gait disturbance and disability. There are at least 40 different genes that are implicated in HSP, but many of these are rare, with only a few affected families worldwide. It is estimated that half of HSP cases are due to mutations in the spastin gene (Spast), which encodes a protein that regulates the cytoskeleton.. There is currently no cure for HSP patients. Pharmacological treatment of HSP patients is limited to the use of muscle relaxants to reduce symptoms of spasticity. Dr Andy Grierson leads a team of researchers based in SITraN at the University of Sheffield. The current focus of HSP research in SITraN is to use disease models to identify new therapeutic approaches.. His team previously developed a spastin mouse model that closely mimics human disease. Mutant spastin mice develop a progressive spastic gait very similar to human HSP patients. Pathologically, the mice show ...
Hereditary spastic paraplegia (HSP) refers to a group of familial diseases that are characterized by progressive degeneration of the corticospinal tracts. Clinically, they present with lower limb spasticity and weakness.HSP, also called familial spas
Genetic testing for up to 65 genes that cause dominant, recessive, and X-linked hereditary spastic paraplegia (HSP), including the most commonly causative genes.
Hereditary spastic paraplegia is a frequently misdiagnosed neurological disorder Medical information in relation to symptoms, diagnosis, misdiagnosis and treatment.
VCP; strumpellin; IBMPFD; hereditary spastic paraplegia; protein aggregate diseases; CELLS SECRETING ANTIBODY; INCLUSION-BODY MYOPATHY; AAA-ATPASE; ENDOPLASMIC-RETICULUM; PAGET-DISEASE; CONTINUOUS CULTURES; LIPID RAFTS; P97; ...
Learn more about Quadriplegia and Paraplegia at Reston Hospital Center DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
NIH Rare Diseases : 52 The following summary is from Orphanet , a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 100988 Definition A rare form of hereditary spastic paraplegia which usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder disturbances and pes cavus. Rarely, it can present as a complex phenotype with additional manifestations including epilepsy , variable peripheral neuropathy and/or memory impairment. Visit the Orphanet disease page for more resources ...
The purpose of this study was to establish the independent influence of SCI level on the change in core temperature and thermoregulatory sweating in athletes with TP (C5-C8), high paraplegia (HP; T1-T5), low paraplegia (LP; T6-L1), and AB controls during exercise in the heat. At a glance: ~50% of the variability in core temperature responses among individuals with paraplegia is explained by injury level.
Scientists at The Scripps Research Institute (TSRI) have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The TSRI researchers found large droplets of triglycerides within the neurons of mice modeling the disease.
When a person moves their arm or hand, they use sensory feedback called proprioception to control that motion. For example, if one reaches out to grab a coffee mug, sensory neurons in the arm and hand send information back to the brain about where ones limbs are positioned and moving. Proprioception tells a person where their arm is positioned, even if their eyes are closed.. But in patients with conditions where sensory neurons die out, executing basic motor tasks such as buttoning a shirt or even walking becomes exceptionally difficult. Paraplegic subjects in the early clinical trials of brain-machine interfaces faced similar difficulty in attempting to move a computer cursor or robot arm using only visual cues. Those troubles helped researchers realize the importance of proprioception feedback, Hatsopoulos said.. In the early days when we were doing this, we didnt even consider sensory feedback as an important component of the system, Hatsopoulos said. We really thought it was just ...
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Spastic paraplegia 4 (SPG4; also known as SPAST-associated HSP) is characterized by insidiously progressive bilateral lower-limb gait spasticity. More than 50% of affected individuals have some weakness in the legs and impaired vibration sense at the ankles. About one third have sphincter disturbances. Onset is insidious, mostly in young adulthood, although symptoms may start as early as age one year and as late as age 76 years. Intrafamilial variation is considerable.
PubMed journal article A case of de novo splice site variant in SLC35A2 showing developmental delays, spastic paraplegia, and delayed myelinatio were found in PRIME PubMed. Download Prime PubMed App to iPhone or iPad.
I am sorry to hear about this patients illness. Potts disease is a severe illness, and there are many different factors that can affect neurologic r
Navigating the claims process can be difficult, especially when you may be trying to recover from a traumatic accident that led to paralysis. We will guide you through the complexities of the claims process one step at a time. Led by Toronto paraplegia lawyer Michael A. Yermus, our team will seek compensation such as income replacement benefits for your:. ...
The aim of this study was to determine the efficacy and the effects of functional electrical stimulated cycling (FES cycling) in patients with spinal cord injury during their rehabilitation in a special acute care unit. Thirty patients [10 with American Spinal Injury Association Impairment Scale (AIS) grade A, three with AIS grade B, 15 with AIS grade C, two with AIS grade D] aged 44±15.5 years and 2 (median) (interquartile range, 1.0-4.25) months after spinal cord injury were included in the study. The patients participated in a 20-min FES-cycling program 2 days per week for 4 weeks during their acute inpatient rehabilitation ...
Four people with paraplegia are able to voluntarily move previously paralyzed muscles as a result of a novel therapy that involves electrical stimulation of the spinal cord, according to a study funded in part by the National Institutes of Health and the Christopher & Dana Reeve Foundation.
4 Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Ankara Physical disability affects the whole life, body functions, life expectations, familial and social role as well as marriage interrelations of the patients. In this study, the paraplegic patients and their relatives perceptions on their own family functions were investigated and compared with the families having no such a patient. Additionally the effects of education level, etiology of injury and disability period on family relations were investigated. 30 married paraplegic patients were enrolled in this study. Control group was comprised of 60 families. Besides demographic features, we used family assessment measurement (FAM) to investigate the impact of the existence of a paraplegic patient in the familial functions. In terms of etiology of injury, disability period and marriage status, there was not statistical significant correlations in family functions (p,0.05). There was a statistical significant ...
A new control strategy that supports the sitting down phase in FES-assisted standing in paraplegia is proposed. It is an adaptation of a well established closed-loop On/Off controller ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ...
Paraplegia occurs when the legs are affected by the spinal cord damage (in thoracic, lumbar, or sacral injuries), and ... Thoracic spinal injuries result in paraplegia, but function of the hands, arms, and neck are not affected. One condition that ... Long term outcomes also range widely, from full recovery to permanent tetraplegia (also called quadriplegia) or paraplegia. ... Paraplegia. 29 (9): 573-81. doi:10.1038/sc.1991.85. PMID 1787981. Field-Fote 2009, p. 8. Yakura, J.S. (Dec 22, 1996). "Recovery ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ...
Harris, Phillip (May 1994). "Miss Joan Scruton MBE". Paraplegia. 32 (5): 362-63. doi:10.1038/sc.1994.62. Hums, Mary (2010). " ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Zettler, P. Is It Cheating to Use ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Dyer, B. An Insight into the Acceptable ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Nolan, Lee; Patritti, Benjamin L.; Stana ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "UCI Cycling Regulations - Para cycling ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Consejo Superior de Deportes (2011). ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Hassani, Hossein; Ghodsi, Mansi; Shadi, ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. IWAS (20 March 2011). "IWF RULES FOR ...
Paraplegia. 1986;24:138-147. Quality of life in patients with spinal cord injury-basic issues, assessment, and recommendations ...
Foo, D; Rossier, AB (Feb 1983). "Anterior spinal artery syndrome and its natural history". Paraplegia. 21 (1): 1-10. doi: ... "Interventions for reversing delayed-onset postoperative paraplegia after thoracic aortic reconstruction". The Annals of ...
Sacral anterior root stimulators for bladder control in paraplegia. Paraplegia. 1982 Dec;20(6):365-81. Holland, Owen; Husbands ...
Paraplegia. 27 (4): 278-83. doi:10.1038/sc.1989.42. PMID 2780083. eMedicine Specialties > Pulmonology > Interstitial Lung ...
Paraplegia. International Medical Society of Paraplegia. 32 (5): 289-291. doi:10.1038/sc.1994.50. PMID 8058344. Retrieved 23 ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Tim-Taek, Oh; Osborough, Conor; Burkett, ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Vanlandewijck, Yves C.; Thompson, Walter ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Labanowich, Stan; Thiboutot, Armand (2011 ...
Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. Miller, Mark D.; Thompson, Stephen R. ( ... Paraplegia. International Medical Society of Paraplegia. 23. Retrieved July 25, 2016. "PARALYMPIC TRACK & FIELD: Officials ...
The magazine Paraplegia News, in an article encouraging its readers to visit Mackinac Island, called the trek around the island ... Paraplegia News. Vol. 61 no. 5. Phoenix: Paralyzed Veterans of America. p. 20. ISSN 0031-1766. OCLC 39535038. Vannoy, Dana (May ...
Anderson, Marty; Metzler, Tim (September 1, 2002). "ESPY winner (Sports & Recreation)". Paraplegia News. Retrieved October 8, ...
Diagnosis: MS).(multiple sclerosis)(Griswold Special Care home-care company for people with special needs)". Paraplegia News. 1 ...
"Escape into the past". PN - Paraplegia News. 65 (5): 49-53. 2011. Retrieved December 12, 2015 - via General OneFile. " ...
... at eMedicine "Primary Lateral Sclerosis". Spastic Paraplegia Foundation. February 15, 2009. Archived ... and absence of family history for Hereditary Spastic Paraplegia (HSP) and ALS. Imaging studies to rule out structural or ...
Brindley GS, Polkey CE, Rushton DN (1982): Sacral anterior root stimulator for bladder control in paraplegia. Paraplegia 20: ...
"Paraplegia - brachydactyly - cone-shaped epiphysis". ORPHANET. Retrieved 2007-03-17. CS1 maint: discouraged parameter (link) ... Fitzsimmons-Guilbert syndrome is an extremely rare genetic disease characterized by a slowly progressive spastic paraplegia, ... Hennekam R (1994). "Spastic paraplegia, dysarthria, brachydactyly, and cone shaped epiphyses: confirmation of the Fitzsimmons ... progressive spastic paraplegia, and brachydactyly type E: a new syndrome or variant of Fitzsimmons-Guilbert syndrome?". Am J ...
LW10 have T5-T10 paraplegia. In 2010, there were three vision impaired classifications, B1, B2 and B3. These classifications ...
Max, D. T. "Can an Unorthodox Operation Cure Paraplegia?". The New Yorker. Retrieved 4 April 2021. Walsh (Medical correspondent ... "Can an Unorthodox Operation Cure Paraplegia?". The New Yorker. Retrieved 30 August 2017. "nsif , Nicholls Spinal Injury ...
For services to those suffering from paraplegia. Captain Basil Henry Liddell Hart, Military Historian. Joseph Anthony Hunt, MBE ...
"Entrez Gene: Spastic paraplegia 9 (autosomal dominant)". Seri M, Cusano R, Forabosco P, Cinti R, Caroli F, Picco P, Bini R, ... Spastic paraplegia 9 (autosomal dominant) is a protein that in humans is encoded by the SPG9 gene. "Human PubMed Reference:". ...
... Aykut Akpınar,1 Bahattin Celik,2 Ihsan Canbek,3 and Ergun Karavelioğlu3 ... He presented to an outside hospital with paraplegia, and then he was transferred to a tertiary center for further management. ... On admission, neurological examination of his motor power was reduced (0/5) in both lower extremities (paraplegia), tendon ... idiopathic spontaneous hematomyelia of a previously healthy 80-year-old male with a sudden onset of back pain and paraplegia. ...
SafetyLit: The weekly online update of injury research and prevention literature. SafetyLit is produced by the Center for Injury Prevention Policy and Practice at San Diego State University.
To describe the occurrence and possible mechanism for aortic saddle embolism as a rare cause of acute paraplegia.,i, Case ... of a 46-year-old female who presented with the sudden onset of nontraumatic low back pain with rapidly progressive paraplegia ... i,Background,/i,. Acute onset paraplegia has a myriad of causes most often of a nonvascular origin. Vascular etiologies are ... Acute Paraplegia as a Presentation of Aortic Saddle Embolism. Lisandro Irizarry. ,1 Anton Wray. ,1 and Kim Guishard1. 1 ...
Learn more about Paraplegia at Doctors Hospital of Augusta DefinitionCausesRisk ... Paraplegia is most often caused by injury or accident. The chance of injury resulting in paraplegia may be reduced by paying ... Paraplegia is the word used to describe the bodys loss of movement and/or feeling. Paraplegia is complete or partial paralysis ... Paraplegia is often the result of an accident. People who participate in high-risk or high-contact sports or those who drive ...
24/7 Paraplegia : A true, personal story from the experience, I Am a Paraplegic. In 07, I kept falling down and ended up in ... 24/7 Paraplegia In 07, I kept falling down and ended up in the local hospital, which was hell,undergoing test after test, ...
If you have suffered paraplegia due to the negligence of another party, we can help you recover the compensation you deserve. ... Definition Of Paraplegia. Paraplegia is a spinal cord injury that prevents movement and sensation in the legs, lower stomach ... Accidents Resulting In Paraplegia. Several causes can lead to paraplegia. In cases where an accident resulted in the injury, ... nearly 8,000 individuals suffer an injury resulting in paraplegia each year. Studies show the most common cause of paraplegia ...
The patient is a 60-year-old female with sudden onset of paraplegia for the last 2 days. She has a previous history of low- ... Sudden Onset of Paraplegia: T2 and T3 Collapse with Abscess. Tuberculosis Case: How to Treat the Abscess?. ... The patient is a 60-year-old female with sudden onset of paraplegia for the last 2 days. She has a previous history of low- ... The patient is recovering from her paraplegia. At 1-month follow-up, she had regained bladder control and has grade 2 power in ...
Raw scores of age, duration, paraplegia score12 and ESR were included. The paraplegia score was obtained using a scale that ... Misra UK, Kalita J. Somatosensory and motor evoked potentials in patients with Potts paraplegia. Paraplegia1996;34:272-6. ... In the present study, the six month outcome of Potts paraplegia was best predicted by power, paraplegia score, CMCT, and CSCT ... We conclude that patients with Potts paraplegia with mild weakness, lower paraplegia score and normal SEP and MEP are likely ...
Some view tetraplegia paraplegia a guide weapons are not speaking responsible sites to congratulate dense today days to choose ... View Tetraplegia Paraplegia A Guide For Physiotherapists 5Th Edition. View Tetraplegia Paraplegia A Guide For Physiotherapists ... be on view tetraplegia paraplegia a guide for of functionality with litis. It therefore s a view tetraplegia paraplegia a ... What can I be to See this in the view tetraplegia paraplegia? If you have on a 14-percent view tetraplegia paraplegia a guide ...
Definition of Painful paraplegia with photos and pictures, translations, sample usage, and additional links for more ... painful paraplegia (current term). painful point. painful sensation. painful toe. painfull. painfuller. painfullest. painfully ... Medical Definition of Painful paraplegia. 1. Paralysis of the lower extremities in which the affected parts, in spite of loss ... Lexicographical Neighbors of Painful Paraplegia. pain measurement. pain pill. pain reaction. pain threshold. pain thresholds. ...
When both legs and arms are affected, the... Explanation of ataxic paraplegia ... Find out information about ataxic paraplegia. paralysis of the lower part of the body, commonly affecting both legs and often ... paraplegia. (redirected from ataxic paraplegia). Also found in: Dictionary, Thesaurus, Medical.. Related to ataxic paraplegia: ... paraplegia. Pathol paralysis of the lower half of the body, usually as the result of disease or injury of the spine ...
Acute paraplegia after vertebroplasty caused by epidural hemorrhage. A case report. by Christof Birkenmaier et al. ... Acute paraplegia after vertebroplasty caused by epidural hemorrhage. A case report.. *. Christof Birkenmaier, Sebastian Seitz, ... article{Birkenmaier2007AcutePA, title={Acute paraplegia after vertebroplasty caused by epidural hemorrhage. A case report.}, ...
Paraplegia. Paraplegia is a devastating reality for many people who endure serious car accidents, water accidents, construction ... Paraplegia devastates victims and families everyday. When your family is faced with a lifetime disability, I will fight for ... I am highly experienced in handling cases of paraplegia and work. My goal is to obtain full compensation for my clients so that ... My name is Adam Davis and I am an experienced attorney dedicated to asserting the rights of paraplegia victims and their ...
I think it is worth clarifying what I wrote a few days back about Robbs diagnosis of acute paraplegia.. Acute is defined as, " ... So, I understand that the doctors may be saying that Robbs paraplegia may be a temporary situation.. Actually, what I really ...
Akibatnya, penderita paraplegia bakalan mengalami kelumpuhan di kedua kaki. Paraplegia seringkali terjadi pada… ... Paraplegia, Penyebab, Gejala dan Cara Mengobatinya. *Posted on Januari 21, 2018. Januari 23, 2018. ... Paraplegia adalah suatu kelainan saraf yang mengakibatkan kehilangan fungsi sensorik (sensasi) serta motorik (gerak) di tungkai ...
Paraplegia : is impairment in motor or sensory function of the lower extremities. It is usually caused by spinal cord injury or ... Paraplegia rehabilitation. Paraplegia : is impairment in motor or sensory function of the lower extremities. It is usually ... The region of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. If all four ... CONTINUATION OF REHABILITATION PROGRAM FOR PARAPLEGIA. *INITIAL REHABILITATION PROGRAM FOR INFANTILE PARALYSIS AND OTHER STATIC ...
... a dispute arose over the new Paraplegia criteria for meeting the definition of catastrophic impairment. ... Accident Benefits Update: New Cat Paraplegia Criteria Tested. March 25, 2020. In Patel v. RSA Insurance (19-000560-AABS), a ... recent decision before the Licence Appeal Tribunal, a dispute arose over the new Paraplegia criteria for meeting the definition ...
Patient Suffers Paraplegia Following Spinal Surgery. August 12, 2016. In The News, Trial UpdatesRaynes Erickson ...
"Hereditary spastic paraplegia". nhs.uk. 2017-10-18. Retrieved 2018-01-28. Fink JK (2003). "The Hereditary Spastic Paraplegias ... GeneReviews/NCBI/NIH/UW entry on Spastic Paraplegia 3A GeneReviews/NCBI/NIH/UW entry on Hereditary Spastic Paraplegia Overview ... Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The ... In the United States, Hereditary Spastic Paraplegia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the ...
Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid paralysis. Deng ... Paraplegia is an impairment in motor or sensory function of the lower extremities. The word comes from Ionic Greek (παραπληγίη ... The area of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. If four limbs ...
Tuberculous paraplegia.. Br Med J 1979; 2 doi: https://doi.org/10.1136/bmj.2.6188.500-a (Published 25 August 1979) Cite this as ...
Source for information on Hereditary Spastic Paraplegia: Gale Encyclopedia of Genetic Disorders dictionary. ... Hereditary spastic paraplegiaDefinitionHereditary spastic paraplegia (HSP) is not a single entity, but a group of clinically ... Hereditary spastic paraplegia. Definition. Hereditary spastic paraplegia (HSP) is not a single entity, but a group of ... Hereditary Spastic Paraplegia. Updated About encyclopedia.com content Print Article Share Article ...
Most commonly, paraplegia is the result of accidents, which occur most often in the young adult male population, between 15 and ... Paraplegia has a host of causes, ranging from the local to the cerebral. ... Paraplegia has a host of causes, ranging from the local to the cerebral. Most commonly, paraplegia is the result of accidents, ... The causes of paraplegia may be classified under the following headings:. Trauma to the spinal cord or brain. *Accidents may ...
... (HSP) refers to a group of familial diseases that are characterized by progressive degeneration ... Classification of the hereditary ataxias and paraplegias. Lancet 1983; 1:1151.. *Fink JK. Hereditary spastic paraplegia ... X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Nat Genet ... Hereditary spastic paraplegia. Authors. Puneet Opal, MD, PhD. Puneet Opal, MD, PhD ...
... is part of a group of genetic disorders known as hereditary spastic paraplegias. Explore symptoms, inheritance, genetics of ... Spastic paraplegia type 7 (also called SPG7) is part of a group of genetic disorders known as hereditary spastic paraplegias. ... Spastic paraplegia type 7 likely accounts for only a small percentage of all spastic paraplegia cases. ... Like all hereditary spastic paraplegias, spastic paraplegia type 7 involves spasticity of the leg muscles and some muscle ...
Spastic paraplegia type 3A is one of a group of genetic disorders known as hereditary spastic paraplegias. Explore symptoms, ... Spastic paraplegia type 3A is one of a group of genetic disorders known as hereditary spastic paraplegias. These disorders are ... Spastic paraplegia type 3A belongs to a subgroup of hereditary spastic paraplegias known as autosomal dominant hereditary ... Spastic paraplegia type 3A accounts for 10 to 15 percent of all autosomal dominant hereditary spastic paraplegia cases. ...
THE TREATMENT OF TRAUMATIC PARAPLEGIA. Br Med J 1918; 1 doi: https://doi.org/10.1136/bmj.1.2975.35-a (Published 05 January 1918 ...
Paraplegia and quadriplegia are forms of paralysis that can result from health issues or physical trauma. Here, learn about the ... Challenges of paraplegia. A person with paraplegia may have limited mobility and sensation in the legs. However, they retain ... Paraplegia can affect the sensory nerves, causing numbness or hypersensitivity. As a result, a person with paraplegia may not ... Paraplegia and quadriplegia are forms of paralysis, which is the partial or complete loss of movement in one or more parts of ...
Paraplegia News and Research. RSS Paraplegia is an impairment in motor or sensory function of the lower extremities. It is ...
In the rehabilitation of paraplegics reconstructive and corrective operations play a not unimportant part. Their chief value lies in assisting conservative measures as a means of speeding up the socia
Paraplegia Guides. * Skin Care and Incontinence: 3 easy steps to prevent incontinence skin problems Apr 27, 2016 by Cindie Hood ... Thousands of Americans living with Paraplegia shop at Allegro Medical to find products that make their lives easier. From the ...
A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and ...
Paraplegia indicates some disorder of the spinal cord, and consists of paralysis of the posterior half (more or less) of the ... Paraplegia - Spinal Paralysis. Paraplegia indicates some disorder of the spinal cord, and consists of paralysis of the ... Paraplegia in the horse is most commonly the result of injury inflicted on the dorsal or lumbar portion of the cord or its ... Paraplegia in the horse, save when arising out of reflex causes, offers very little encouragement to treatment. Injury to the ...
paraplegia dolorosa synonyms, paraplegia dolorosa pronunciation, paraplegia dolorosa translation, English dictionary definition ... of paraplegia dolorosa. n. Complete paralysis of the lower half of the body including both legs, usually caused by damage to ... paraplegia. [ˌpærəˈpliːdʒə] n → paraplegia. par·a·ple·gi·a n. paraplejía, parálisis de la parte inferior del tronco y de las ... paraplegia. (redirected from paraplegia dolorosa). Also found in: Thesaurus, Medical, Encyclopedia. par·a·ple·gia. (păr′ə-plē′ ...
Spastic paraplegia 4 (SPG4; also known as SPAST-associated HSP) is characterized by insidiously progressive bilateral lower- ... Spastic paraplegia type 4 is a pure hereditary spastic paraplegia.Like all hereditary spastic paraplegias, spastic paraplegia ... Familial spastic paraplegia autosomal dominant 2; Spastic Paraplegia 4; SPG4. Modes of inheritance:. Autosomal dominant ... Spastic paraplegia type 4 is part of a group of genetic disorders known as hereditary spastic paraplegias. These disorders are ...
Hereditary spastic paraplegia (HSP) is not a single disease entity; it is a group of clinically and genetically diverse ... Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working Group. Neurology. 1996 Jun. ... encoded search term (Hereditary Spastic Paraplegia) and Hereditary Spastic Paraplegia What to Read Next on Medscape ... Hereditary Spastic Paraplegia Clinical Presentation. Updated: Jan 14, 2019 * Author: Nam-Jong Paik, MD, PhD; Chief Editor: ...
New exercise device design for people with paraplegia Retrofitted rowing machines allow people with paraplegia to exercise ... allowing people with para-plegia to exer-cise without the aid of a trainer. The Capstone group recently filed... view more ... was that some two dozen patients living with a med-ical con-di-tion known as spastic para-plegia lacked suf-fi-cient motor con- ... allowing people with para-plegia to exer-cise without the aid of a trainer. ...
We help people affected by Hereditary Spastic Paraplegia (HSP), their families and carers by the provision of support, ... If youd like to support The Hereditary Spastic Paraplegia Support Group just click the links below: ...
Hereditary spastic paraplegia is a condition in which a person experiences a gradual but continuous development of weakness and ... In hereditary spastic paraplegia, there is often a gradual deterioration in the nerves that control the muscles of the legs. ... Hereditary spastic paraplegia (HSP), also referred to as Strumpell-Lorrain disease, familial spastic paraparesis, and spastic ... In uncomplicated hereditary paraplegia, patients usually experience mostly muscle weakness and stiffness in the legs. At the ...
Hereditary spastic paraplegia (HSP) is a syndrome designation describing inherited disorders in which lower extremity weakness ... Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.. Fink JK1. ... Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms. Acta Neuropathol. ;126(3):307-328 ... MalaCards for spastic paraplegia 39 - The Weizmann Institute of Science GeneCards and MalaCards databases ...
The NINDS supports research on genetic disorders such as HSP. More than 30 genes that are responsible for several forms of HSP have been identified, and many more will likely be identified in the future. These genes generally encode proteins that normally help maintain the function of axons in the spinal cord. Understanding how mutations of these genes cause HSP should lead to ways to prevent, treat, and cure HSP.. Information from the National Library of Medicines MedlinePlus ...
Hereditary spastic paraplegia (HSP) is not a single disease entity; it is a group of clinically and genetically diverse ... encoded search term (Hereditary Spastic Paraplegia) and Hereditary Spastic Paraplegia What to Read Next on Medscape. Related ... Hereditary spastic paraplegia: advances in genetic research. Hereditary Spastic Paraplegia Working Group. Neurology. 1996 Jun. ... Hereditary Spastic Paraplegia Workup. Updated: Jan 14, 2019 * Author: Nam-Jong Paik, MD, PhD; Chief Editor: Stephen Kishner, MD ...
Spastic paraplegia type 3A Spastic paraplegia type 4 Spastic paraplegia type 49 Spastic paraplegia type 5A Spastic paraplegia ... Spastic paraplegia type 11 Spastic paraplegia type 15 Spastic paraplegia type 2 Spastic paraplegia type 31 ... Paraplegia. Spastic Paraplegia, Hereditary. Hereditary Sensory and Motor Neuropathy. Muscular Diseases. Musculoskeletal ... Genetic and Rare Diseases Information Center resources: Paraplegia Hereditary Spastic Paraplegia Infantile-onset Ascending ...
Fluorosis… causing paraplegia… mutilating life…. Source: Journal of the Pakistan Medical Association 66(2):213-6. , February ... A case of 26 years old female from Thul, Sindh, who presented with paraplegia, is reported here. Her MRI showed extensive ... Full article online at https://www.thefreelibrary.com/Fluorosis…+causing+paraplegia…+mutilating+life…-a0451877871 ...
Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous group of neurodegenerative disorders ... Molecular Aspects of Hereditary Spastic Paraplegia Exp Cell Res. 2014 Jul 1;325(1):18-26. doi: 10.1016/j.yexcr.2014.02.021. ... Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous group of neurodegenerative disorders ...
  • To describe the occurrence and possible mechanism for aortic saddle embolism as a rare cause of acute paraplegia. (hindawi.com)
  • Acute paraplegia after vertebroplasty caused by epidural hemorrhage. (semanticscholar.org)
  • We present idiopathic spontaneous hematomyelia of a previously healthy 80-year-old male with a sudden onset of back pain and paraplegia. (hindawi.com)
  • Described is a case of a 46-year-old female who presented with the sudden onset of nontraumatic low back pain with rapidly progressive paraplegia which was subsequently determined to be of vascular origin. (hindawi.com)
  • Presented is a rare case of aortic saddle embolism associated with the sudden onset of low back pain and acute onset paraplegia. (hindawi.com)
  • The patient is a 60-year-old female with sudden onset of paraplegia for the last 2 days. (spineuniverse.com)
  • The region of the spinal canal that is affected in paraplegia is either the thoracic, lumbar, or sacral regions. (cubaheal.com)
  • The lower body parts affected by paraplegia are either lumbar, sacral, or thoracic regions (Shields, 2002). (marvelousessay.org)
  • In Patel v. RSA Insurance (19-000560-AABS), a recent decision before the Licence Appeal Tribunal, a dispute arose over the new Paraplegia criteria for meeting the definition of catastrophic impairment. (campisilaw.ca)
  • Paraplegia is an impairment of the lower parts of the body such as legs as a result of spinal cord damage. (marvelousessay.org)
  • Studies show the most common cause of paraplegia is motor vehicle accidents, followed by violent acts, falls and sports injuries. (pfaffgill.com)
  • If an individual's paraplegia is caused by another party's negligence or recklessness, victims are entitled to compensation for their injuries, permanent disabilities, financial losses, suffering and other losses. (pfaffgill.com)
  • Walsh (2004) suggests that paraplegia is mostly caused by traumatic injuries of the spinal cord and nervous tissue resulting to swelling and inflammation at the point of trauma. (marvelousessay.org)
  • In addition, direct injuries such as a cut to the spine may cause paraplegia, particularly when the vertebra is traumatized. (marvelousessay.org)
  • Although trauma, such as violence and car accidents, is among the most common causes of paraplegia, this condition can be caused by genetic factors, spinal tumors and other medical complications. (pfaffgill.com)
  • It was learnt that the deceased had a history of paraplegia due to a spinal injury in 2019, he had been on medication and was travelling to Abuja for a medical examination. (latestnigeriannews.com)
  • When an accident occurs, it is the trauma that can result in paraplegia. (pfaffgill.com)
  • Paraplegia occurs due to spinal cord damage, which may result to the loss of movement ability, relaxation, and sensation below the area where the spinal cord is damaged. (marvelousessay.org)
  • Paraplegia secondary to just vertebral destruction, kyphosis, and epidural abscess is typically best treated through surgical means assuming that the patient can tolerate the procedure and is hemodynamically stable. (spineuniverse.com)
  • These illnesses damage spinal nerves which are irreparable, hence causing permanent paraplegia (Walsh,2004). (marvelousessay.org)
  • Injury to the nervous system is the most common cause of paraplegia. (doctors-hospital.net)
  • If you have an injury that causes paraplegia, emergency treatment is needed to prevent further damage to the nervous system. (doctors-hospital.net)
  • Paraplegia is the word used to describe the body's loss of movement and/or feeling. (doctors-hospital.net)
  • Paraplegia is a spinal cord injury that prevents movement and sensation in the legs, lower stomach region and/or lower back region. (pfaffgill.com)
  • The onset of nontraumatic paraplegia represents a significant event for the patient and an emergent diagnostic challenge for the clinician. (hindawi.com)
  • Because the patient was 60-years-old and had experienced a rapid onset of paraplegia, surgery was preferred. (spineuniverse.com)
  • The patient is recovering from her paraplegia. (spineuniverse.com)
  • Surgery, physical therapy and medications are among the treatments for paraplegia. (pfaffgill.com)
  • On admission, neurological examination of his motor power was reduced (0/5) in both lower extremities (paraplegia), tendon reflexes in both lower limbs had increased, Babinski responses were positive, there was anesthesia/hypoesthesia for light touch, and there was hypoesthesia below the thoracal (T5-T6) dermatome. (hindawi.com)
  • Reexamination revealed pallor to the lower extremities, nonpalpable distal pulses, and decreased temperature to touch with near complete paraplegia. (hindawi.com)
  • Permanent paraplegia may also affect muscular functioning, thus resulting to partial or complete loss of muscle functions that may be permanent. (marvelousessay.org)
  • The etiology of paraplegia is broad and includes disorders of the spinal cord which encompass external compression, infection, ischemia, and other nonspinal disorders. (hindawi.com)
  • In the case of permanent paraplegia, a condition called muscle atrophy develops. (marvelousessay.org)
  • Paraplegia is most often caused by injury or accident. (doctors-hospital.net)
  • The chance of injury resulting in paraplegia may be reduced by paying careful attention to environmental factors. (doctors-hospital.net)
  • According to the University of Alabama National Spinal Cord Injury Statistical Center, nearly 8,000 individuals suffer an injury resulting in paraplegia each year. (pfaffgill.com)
  • If you've suffered an injury that resulted in paraplegia, we are committed to fighting aggressively on your behalf to ensure that you recover the compensation you need and deserve. (pfaffgill.com)
  • If you or a loved one has suffered a serious spinal cord injury that resulted in paraplegia, contact Pfaff, Gill & Ports, Ltd., for help today. (pfaffgill.com)
  • Spastic paraplegia is a form of paraplegia defined by spasticity of the affected muscles, rather than flaccid paralysis. (wikipedia.org)
  • When the only manifested symptom is progressive spasticity, HSP is also known as pure hereditary spastic paraplegia. (encyclopedia.com)
  • Like all hereditary spastic paraplegias, spastic paraplegia type 7 involves spasticity of the leg muscles and some muscle weakness. (medlineplus.gov)
  • These disorders are characterized by muscle stiffness (spasticity) and weakness in the lower limbs (paraplegia). (medlineplus.gov)
  • A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. (uniprot.org)
  • As previously mentioned, hereditary spastic paraplegia (HSP) is not a single disease entity but a group of clinically and genetically diverse disorders that cause progressive and generally severe lower extremity weakness and spasticity. (medscape.com)
  • Hereditary spastic paraplegia (HSP) is a syndrome designation describing inherited disorders in which lower extremity weakness and spasticity are the predominant symptoms. (nih.gov)
  • Hereditary spastic paraplegia (HSP) is a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by progressive lower limbs spasticity and weakness. (nih.gov)
  • Spastic paraplegia of unknown origin is a movement disorder in which there is progressive weakness and spasticity (stiffness) of the legs. (patientslikeme.com)
  • Hereditary spastic paraplegias (HSPs) are a group of neurodegenerative disorders marked by lower-limb spasticity (stiffness) and weakness, leading to progressive difficulty walking. (sdbonline.org)
  • The human PAPLA1 phospholipase family is associated with hereditary spastic paraplegia (HSP) , a neurodegenerative syndrome characterized by progressive spasticity and weakness of the lower limbs. (sdbonline.org)
  • Hereditary spastic paraplegia, or HSP, refers to a clinical designation for neurological syndromes characterized by bilateral lower limb spasticity, or stiffness and weakness, which are caused by gene mutation and therefore they are inherited. (hstalks.com)
  • Hereditary Spastic Paraplegia (HSP) is a heterogeneous group of inherited neurodegenerative disorders with weakness and spasticity of the lower limbs as its main clinical feature. (omicsonline.org)
  • Hereditary spastic paraplegia (HSP), which is also known as Strumpell-Lorraine disease, is a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and weakness of the lower extremities [ 1 , 2 , 3 ]. (mdpi.com)
  • Some people with paraplegia also have something called spasticity which is an increase in muscle tone that can cause stiffness and spasms in the legs. (healthtap.com)
  • Hereditary spastic paraplegias (HSPs) are a family of such diseases attributed to over 80 spastic gait genes (SPG), specifically characterized by lower extremity spasticity and weakness. (frontiersin.org)
  • These disorders are characterized by muscle stiffness (spasticity) and severe weakness in the lower limbs (paraplegia). (malacards.org)
  • In incomplete paraplegia the hind-quarters roll from side to side, the animal crosses his hind-limbs, sometimes trails the toes, or knuckles over with the fetlock joints. (chestofbooks.com)
  • Complete paraplegia is when a person loses both feeling and movement below his or her injury, while incomplete paraplegia is when a person maintains some movement or feeling below the injury. (bdjinjurylawyers.com)
  • These cases frequently result in dramatically higher treatment, rehabilitation, and accommodation costs, but even cases of incomplete paraplegia can result in millions of dollars' worth of bills of your lifetime. (njlawyers.com)
  • Effects of Etiology on Inpatient Rehabilitation Outcomes in 65-74 Year Olds with Incomplete Paraplegia from a Non-traumatic Spinal Cord Injury. (rti.org)
  • Autosomal recessive spastic paraplegia type 32 (SPG32) is a rare, complex type of hereditary spastic paraplegia characterized by a slowly progressive spastic paraplegia (with walking difficulties appearing at onset at 6-7 years of age) associated with mild intellectual disability . (nih.gov)
  • These genes are generically known as spastic paraplegia gene, or SPG. (encyclopedia.com)
  • Mutational spectrum of the SPG4 (SPAST) and SPG3A (ATL1) genes in Spanish patients with hereditary spastic paraplegia. (medlineplus.gov)
  • HSP is linked to mutations in several loci known collectively as the spastic paraplegia genes (SPGs). (jci.org)
  • Presents a current understanding of the normal and pathological functioning of the genes responsible for ataxias and spastic paraplegias. (elsevier.com)
  • Within many multiplex families it is highly variable, although mutations in certain genes, notably spastic paraplegia gene (SPG) 3A/atlastin1, are predominantly associated with a childhood age at onset. (springer.com)
  • The definition of paraplegia is fairly wide, and paraplegics can experience anything from a slight impairment of leg movement to complete loss of leg movement all the way up to the chest. (brainandspinalcord.org)
  • What is the definition or description of: Paraplegia? (healthtap.com)
  • Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. (curehunter.com)
  • I will use the physiopathology of certain forms of hereditary spastic paraplegia (HSP) as a model to understand why and how alteration of ER dynamics in neurons can lead to neurodegeneration. (europa.eu)
  • Primary outcome assessment of this study was the change between baseline and follow-up assessment in treatment to control group in the spastic paraplegia rating scale (SPRS) score as a validated measure of disease severity (see Reference). (clinicaltrials.gov)
  • Clinical severity was assessed by the Spastic Paraplegia Rating Scale. (uni-muenchen.de)
  • The main outcome measure for a subset of the cohort (n = 48) was the Spastic Paraplegia Rating Scale. (ovid.com)
  • An important gene associated with Spastic Paraplegia 5a is CYP7B1 (Cytochrome P450 Family 7 Subfamily B Member 1). (malacards.org)
  • Engineers have developed a new type of microchip muscle stimulator implant that will enable people with paraplegia to exercise their paralysed leg muscles. (scienceblog.com)
  • HSP is also known as hereditary spastic paraparesis, familial spastic paraplegia, French settlement disease, Strumpell disease, or Strumpell-Lorrain disease. (wikipedia.org)
  • People sometimes use the term "paraplegia" interchangeably with "paraparesis," which is partial paralysis in the lower body due to muscle weakness and stiffness. (medicalnewstoday.com)
  • Hereditary spastic paraplegia (HSP), also referred to as Strumpell-Lorrain disease, familial spastic paraparesis , and spastic paraplegia, belongs to a group of rare genetic disorders that affect the nervous system. (wisegeek.com)
  • Spastic Paraplegia-Paraparesis. (nih.gov)
  • During a 16-year period 672 patients were admitted to the Columbia Presbyterian Medical Center with spastic paraplegia-paraparesis (SPP) as a prominent finding. (nih.gov)
  • Hereditary spastic paraplegia (HSP), also called hereditary spastic paraparesis, familial spastic paralysis and Strümpell-Lorrain syndrome was first reported in 1876 by Seeligmüller, followed by reports by Strumpell and Lorraine. (omicsonline.org)
  • Neurological dysfunction resulting from transient spinal cord ischemia may be clinically expressed as paraparesis, fully-developed spastic paraplegia, or flaccid paraplegia. (ca.gov)
  • Whereas cases presenting with paraparesis have been treated with either surgery or radiotherapy with equal frequency and efficacy, almost all reported cases with paraplegia have been treated with surgery with or without radiation therapy. (haematologica.org)
  • Paraplegia is an impairment in motor or sensory function of the lower extremities. (wikipedia.org)
  • This page presents a variety of statistics about Neuropathy sensory spastic paraplegia. (rightdiagnosis.com)
  • The term 'prevalence' of Neuropathy sensory spastic paraplegia usually refers to the estimated population of people who are managing Neuropathy sensory spastic paraplegia at any given time. (rightdiagnosis.com)
  • The term 'incidence' of Neuropathy sensory spastic paraplegia refers to the annual diagnosis rate, or the number of new cases of Neuropathy sensory spastic paraplegia diagnosed each year. (rightdiagnosis.com)
  • Nonfunctional m-AAA proteases cause a build up of unusable proteins in the mitochondria of nerve cells, which can result in swelling of the cell, reduced cell signaling, and impaired cell movement, leading to the major signs and symptoms of spastic paraplegia type 7. (medlineplus.gov)
  • This impaired nerve function leads to the signs and symptoms of spastic paraplegia type 3A. (medlineplus.gov)
  • Patients with complicated hereditary spastic paraplegia often experience similar symptoms in the legs, but they usually have additional nervous system problems. (wisegeek.com)
  • What symptoms can a person expect to result from paraplegia? (bdjinjurylawyers.com)
  • What are the symptoms associated with paraplegia? (healthtap.com)
  • Group for the Study of the Genetics of Spastic Paraplegia. (medlineplus.gov)
  • Today I'm going to talk about the genetics of hereditary spastic paraplegia. (hstalks.com)
  • HSPs are clinically differentiated into 'pure' forms if spastic paraplegia with bladder involvement is the only clinical finding, and 'complicated' (or complex) forms if there are additional neurologic or systemic abnormalities. (uptodate.com)
  • Hereditary spastic paraplegias (HSPs) are a group of neurodegenerative diseases causing progressive gait dysfunction. (sdbonline.org)
  • The locomotor deficits in the hereditary spastic paraplegias (HSPs) reflect degeneration of upper motor neurons, but the mechanisms underlying this neurodegeneration are unknown. (sdbonline.org)
  • ObjectiveHereditary spastic paraplegias (HSPs) are genetically driven disorders with the hallmark of progressive spastic gait disturbance. (uni-muenchen.de)
  • The hereditary spastic paraplegias (HSPs) are a group of genetic conditions in which spastic paralysis of the legs is the principal clinical feature. (springer.com)
  • Hereditary spastic paraplegias (HSPs) are a group of neurodegenerative disorders that result from degeneration of corticospinal tract axons. (lsu.edu)
  • The chance of injury resulting in paraplegia may be reduced by paying careful attention to environmental factors. (doctors-hospital.net)
  • According to the University of Alabama National Spinal Cord Injury Statistical Center, nearly 8,000 individuals suffer an injury resulting in paraplegia each year. (pfaffgill.com)
  • Injury to the nervous system is the most common cause of paraplegia. (doctors-hospital.net)
  • Studies show the most common cause of paraplegia is motor vehicle accidents, followed by violent acts, falls and sports injuries. (pfaffgill.com)
  • Spastic paraplegia type 7 (also called SPG7) is part of a group of genetic disorders known as hereditary spastic paraplegias. (medlineplus.gov)
  • Spastic paraplegia type 3A is one of a group of genetic disorders known as hereditary spastic paraplegias. (medlineplus.gov)
  • HSP, also called familial spastic paraplegia, was initially referred to as Strumpell-Lorrain disease, a name given for the two physicians who in the late 19th century independently described key features of spastic paraplegia. (uptodate.com)
  • Mutations in the SPG7 gene cause spastic paraplegia type 7. (medlineplus.gov)
  • Mutations affecting reticulon or REEP proteins, with intramembrane hairpin domains that model ER membranes, cause an axon degenerative disease, hereditary spastic paraplegia (HSP). (elifesciences.org)
  • It is known that spastic paraplegias are sometimes caused by mutations affecting proteins that help to build and shape the endoplasmic reticulum, for example, the proteins of the reticulon and REEP families. (elifesciences.org)
  • Spastic paraplegia 7 is an autosomal recessive disorder caused by mutations in the gene encoding paraplegin, a protein located at the inner mitochondrial membrane and involved in the processing of other mitochondrial proteins. (uib.no)
  • Paraplegia is often not associated with mental retardation or epilepsy , while quadriplegia is almost always associated with both. (healthtap.com)
  • If the survivor has sustained an injury that is below the first thoracic spinal nerve, this will result in paraplegia, the loss of sensation or movement-to some degree-in the legs, bowel, bladder, and sexual region. (brainandspinalcord.org)
  • When an accident occurs, it is the trauma that can result in paraplegia. (pfaffgill.com)
  • Surgery, physical therapy and medications are among the treatments for paraplegia. (pfaffgill.com)
  • Are there treatments for paraplegia? (healthtap.com)
  • Quality Of Life of Individuals with Paraplegia in Punjab. (ozon.ru)
  • The information about Quality of Life of individuals with Paraplegia in developing countries has not been reported extensively. (ozon.ru)
  • The project is an effort to evaluate the Quality Of Life of individuals with Paraplegia in Punjab via application of scales for ambulatory status, functional independence and community reintegration. (ozon.ru)
  • The aim of this study is to assess the impact of gait training using H-MEX powered exoskeleton on walking ability, gait analysis, medical examination, body composition, functional evaluation, laboratory findings, quality of life, and subjective experience in individuals with paraplegia. (bioportfolio.com)
  • Spastic paraplegia type 3A is usually a pure hereditary spastic paraplegia, although a few complex cases have been reported. (medlineplus.gov)
  • Spastic paraplegia type 5A is usually a pure hereditary spastic paraplegia, although complex type features have been reported in some individuals, usually in those who have had the condition for many years. (malacards.org)
  • Here, we have demonstrated that the two most common autosomal recessive hereditary spastic paraplegia gene products, the SPG15 protein spastizin and the SPG11 protein spatacsin, are pivotal for autophagic lysosome reformation (ALR), a pathway that generates new lysosomes. (jci.org)
  • A hereditary spastic paraplegia that has_material_basis_in mutation in the PLP1 gene on chromosome Xq22.2. (jax.org)
  • A hereditary spastic paraplegia that has_material_basis_in mutation in the SPG11 gene on chromosome 15q21. (jax.org)
  • In uncomplicated hereditary paraplegia, patients usually experience mostly muscle weakness and stiffness in the legs. (wisegeek.com)
  • Paraplegia= weakness or paralysis of the 2 lower extremities. (healthtap.com)
  • Patients with Pott's paraplegia are likely to recover completely by six months if they have mild weakness, lower paraplegia score and normal SEPs and MEPs. (bmj.com)
  • Acute onset paraplegia has a myriad of causes most often of a nonvascular origin. (hindawi.com)
  • This is the first case report describing delayed-onset paraplegia due to spinal cord ischemia caused by embolization of segmental arteries and ligation of nerve roots in multi-spinal levels for spine tumor surgeries. (healio.com)
  • During aneurysm repair, these new arteries provide an alternate blood supply to the spinal cord and thereby help prevent paraplegia. (europa.eu)
  • The lack of mechanistic understanding of spinal cord ischemia-reperfusion injury has hindered further adjuncts to prevent paraplegia following high risk aortic operations. (jove.com)
  • Reexamination revealed pallor to the lower extremities, nonpalpable distal pulses, and decreased temperature to touch with near complete paraplegia. (hindawi.com)
  • Complete paraplegia is extremely rare in EMH due to thalassemia although it is known to occur in polycythemia vera and sickle cell anemia. (haematologica.org)
  • Only isolated reports have described patients with complete paraplegia, none of whom have been treated with radiotherapy alone. (haematologica.org)
  • Classification of the hereditary ataxias and paraplegias. (uptodate.com)
  • One of the most serious injuries anyone can suffer following damage to their spinal cord is paralysis, also referred to as paraplegia or quadriplegia / tetraplegia depending on how much of the victim's body is affected. (njlawyers.com)
  • Mast syndrome is an autosomal recessive, complicated form of hereditary spastic paraplegias associated with dementia that has been found in the Old Order Amish population. (uhhospitals.org)
  • Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. (wikipedia.org)
  • Enabling Task-Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia appeared in the April 2017 issue of Mayo Clinic Proceedings. (mayoclinic.org)
  • A study by Pascual et al indicated that the appearance of the ears-of-the-lynx sign on fluid-attenuated inversion recovery (FLAIR) MRI-a sign consisting of changes to the periventricular white matter in the frontal horn region that resemble hair tufts on lynx ears-is highly specific for the presence of "the most common genetic subtypes of hereditary spastic paraplegia with a thin corpus callosum. (medscape.com)
  • SPG15 is the second most common cause of hereditary spastic paraplegia with thin corpus callosum. (natureasia.com)
  • On admission, neurological examination of his motor power was reduced (0/5) in both lower extremities (paraplegia), tendon reflexes in both lower limbs had increased, Babinski responses were positive, there was anesthesia/hypoesthesia for light touch, and there was hypoesthesia below the thoracal (T5-T6) dermatome. (hindawi.com)
  • The major neurological deficit resulting from spinal ischemic injury is the loss of motor function in lower extremities, also called paraplegia. (ca.gov)
  • A study by Schlipf et al indicates that since clinical parameters alone are not reliable enough to differentiate between types of hereditary spastic paraplegia (HSP), specifically autosomal recessive (AR) HSP, that amplicon-based high-throughput genotyping followed by pooled next-generation sequencing (NGS) is a much more efficient approach. (medscape.com)
  • PAPA-ARTiS is a multi-national, prospective, open-label, two-arm, randomized controlled trial to demonstrate, that a minimally invasive staged treatment approach can reduce paraplegia and mortality in patients undergoing thoracoabdominal aortic aneurysm (TAAA) repair and to assess the clinical safety of the novel therapeutic concept (MIS2ACE). (europa.eu)
  • To describe the clinical, genetic, and epidemiologic features of hereditary spastic paraplegia (HSP) in Canada and to determine which clinical, radiologic, and genetic factors determine functional outcomes for patients with HSP. (ovid.com)
  • To evaluate the prognostic significance of various clinical, radiological, and neurophysiological findings in conservatively treated patients with Pott's paraplegia, using multiple regression analysis. (bmj.com)
  • 6- 9 In the present communication we report the role of various clinical, MRI, and evoked potential changes in predicting the six month outcome of conservatively treated patients with Pott's paraplegia. (bmj.com)
  • Briefly, the typical clinical picture is of a slowly progressive, predominantly symmetrical, spastic paraplegia. (springer.com)
  • Participants with paraplegia will attend gait training using H-MEX powered exoskeleton 3 times a week for 10 weeks. (bioportfolio.com)
  • Paraplegia from a bilateral cerebral lesion. (thefreedictionary.com)
  • A) in a female patient who showed severe developmental delay, spastic paraplegia, mild cerebral atrophy, and delayed myelination on MRI, but no seizures. (unboundmedicine.com)