A convolution on the inferior surface of each cerebral hemisphere, lying between the hippocampal and collateral sulci.
Lower lateral part of the cerebral hemisphere responsible for auditory, olfactory, and semantic processing. It is located inferior to the lateral fissure and anterior to the OCCIPITAL LOBE.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.
GRAY MATTER situated above the GYRUS HIPPOCAMPI. It is composed of three layers. The molecular layer is continuous with the HIPPOCAMPUS in the hippocampal fissure. The granular layer consists of closely arranged spherical or oval neurons, called GRANULE CELLS, whose AXONS pass through the polymorphic layer ending on the DENDRITES of PYRAMIDAL CELLS in the hippocampus.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.
Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
A set of forebrain structures common to all mammals that is defined functionally and anatomically. It is implicated in the higher integration of visceral, olfactory, and somatic information as well as homeostatic responses including fundamental survival behaviors (feeding, mating, emotion). For most authors, it includes the AMYGDALA; EPITHALAMUS; GYRUS CINGULI; hippocampal formation (see HIPPOCAMPUS); HYPOTHALAMUS; PARAHIPPOCAMPAL GYRUS; SEPTAL NUCLEI; anterior nuclear group of thalamus, and portions of the basal ganglia. (Parent, Carpenter's Human Neuroanatomy, 9th ed, p744; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (September 2, 1998)).
The thin layer of GRAY MATTER on the surface of the CEREBRAL HEMISPHERES that develops from the TELENCEPHALON and folds into gyri and sulchi. It reaches its highest development in humans and is responsible for intellectual faculties and higher mental functions.
Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury.
A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)
Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
A pair of nuclei and associated gray matter in the interpeduncular space rostral to the posterior perforated substance in the posterior hypothalamus.
Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.
Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
The knowledge or perception that someone or something present has been previously encountered.
Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.
Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual sensory information. It is located posterior to the parieto-occipital sulcus and extends to the preoccipital notch.
Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs.
Dominance of one cerebral hemisphere over the other in cerebral functions.
The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.
Neural tracts connecting one part of the nervous system with another.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the MEDIODORSAL NUCLEUS OF THE THALAMUS. The prefrontal cortex receives afferent fibers from numerous structures of the DIENCEPHALON; MESENCEPHALON; and LIMBIC SYSTEM as well as cortical afferents of visual, auditory, and somatic origin.
A meshlike structure composed of interconnecting nerve cells that are separated at the synaptic junction or joined to one another by cytoplasmic processes. In invertebrates, for example, the nerve net allows nerve impulses to spread over a wide area of the net because synapses can pass information in any direction.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
The process whereby a representation of past experience is elicited.
Cerebral cortex region on the medial aspect of the PARAHIPPOCAMPAL GYRUS, immediately caudal to the OLFACTORY CORTEX of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the HIPPOCAMPAL FORMATION, the so-called PERFORANT PATHWAY.
Upper central part of the cerebral hemisphere. It is located posterior to central sulcus, anterior to the OCCIPITAL LOBE, and superior to the TEMPORAL LOBES.
The selecting and organizing of visual stimuli based on the individual's past experience.
One of the convolutions on the medial surface of the CEREBRAL HEMISPHERES. It surrounds the rostral part of the brain and CORPUS CALLOSUM and forms part of the LIMBIC SYSTEM.
A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
Almond-shaped group of basal nuclei anterior to the INFERIOR HORN OF THE LATERAL VENTRICLE of the TEMPORAL LOBE. The amygdala is part of the limbic system.
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
The time from the onset of a stimulus until a response is observed.
Those affective states which can be experienced and have arousing and motivational properties.
A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.
Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.
The awareness of the spatial properties of objects; includes physical space.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Intellectual or mental process whereby an organism obtains knowledge.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
Heavily myelinated fiber bundle of the TELENCEPHALON projecting from the hippocampal formation to the HYPOTHALAMUS. Some authorities consider the fornix part of the LIMBIC SYSTEM. The fimbria starts as a flattened band of axons arising from the subiculum and HIPPOCAMPUS, which then thickens to form the fornix.
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
A term used in Eastern European research literature on brain and behavior physiology for cortical functions. It refers to the highest level of integrative function of the brain, centered in the CEREBRAL CORTEX, regulating language, thought, and behavior via sensory, motor, and cognitive processes.
Reactions of an individual or groups of individuals with relation to the immediate surrounding area including the animate or inanimate objects within that area.
Type of declarative memory, consisting of personal memory in contrast to general knowledge.
Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
Elements of limited time intervals, contributing to particular results or situations.
The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.
The coordination of a sensory or ideational (cognitive) process and a motor activity.
The persistence to perform a learned behavior (facts or experiences) after an interval has elapsed in which there has been no performance or practice of the behavior.
A physical property showing different values in relation to the direction in or along which the measurement is made. The physical property may be with regard to thermal or electric conductivity or light refraction. In crystallography, it describes crystals whose index of refraction varies with the direction of the incident light. It is also called acolotropy and colotropy. The opposite of anisotropy is isotropy wherein the same values characterize the object when measured along axes in all directions.
A prodromal phase of cognitive decline that may precede the emergence of ALZHEIMER DISEASE and other dementias. It may include impairment of cognition, such as impairments in language, visuospatial awareness, ATTENTION and MEMORY.

Auditory thalamus, dorsal hippocampus, basolateral amygdala, and perirhinal cortex role in the consolidation of conditioned freezing to context and to acoustic conditioned stimulus in the rat. (1/246)

On the basis of previous experimental evidence, it is known that the auditory thalamus (AT), the dorsal hippocampus (DH), the basolateral amygdala (BLA), and the perirhinal cortex (PC) are involved in the mnemonic processing of conditioned freezing. In particular, BLA and PC appear to be involved both in conditioned stimulus (CS) and context conditioned freezing. Through AT, the auditory CS is sent to other sites, whereas DH is involved in context conditioning. Nevertheless, the existing evidence does not make it possible to assess AT, DH, BLA, and PC involvement during the consolidation phase of conditioned freezing. To address this question, fully reversible tetrodotoxin (TTX) inactivation was performed on adult male Wistar rats having undergone CS and context fear training. Anesthetized animals were injected stereotaxically with TTX (either 5 or 10 ng in 0.5 or 1.0 microliter of saline, according to site dimensions) at increasing post-acquisition delays. Context and CS freezing durations were measured during retention testing, always performed 48 and 72 hr after TTX administration. The results showed that AT inactivation does not disrupt consolidation of either contextual or auditory fear memories. In contrast, inactivation of the other three structures disrupted consolidation. For the DH, this disruption was specific to contextual cues and only occurred when inactivation was performed early (up to 1.5 hr) after training. The BLA and PC were shown to be involved in the consolidation of both contextual and auditory fear. Their involvement persisted for longer periods of time (2d for BLA and 8 d for PC). These findings provide information to build a temporal profile for the post-training processing of fear memories in structures known to be important for this form of learning. The results are discussed in relation to previous studies on conditioned freezing and other aversive conditioned response neural correlates.  (+info)

Planum temporale and Heschl gyrus volume reduction in schizophrenia: a magnetic resonance imaging study of first-episode patients. (2/246)

BACKGROUND: Magnetic resonance imaging studies in schizophrenia have revealed abnormalities in temporal lobe structures, including the superior temporal gyrus. More specifically, abnormalities have been reported in the posterior superior temporal gyrus, which includes the Heschl gyrus and planum temporale, the latter being an important substrate for language. However, the specificity of the Heschl gyrus and planum temporale structural abnormalities to schizophrenia vs affective psychosis, and the possible confounding roles of chronic morbidity and neuroleptic treatment, remain unclear. METHODS: Magnetic resonance images were acquired using a 1.5-T magnet from 20 first-episode (at first hospitalization) patients with schizophrenia (mean age, 27.3 years), 24 first-episode patients with manic psychosis (mean age, 23.6 years), and 22 controls (mean age, 24.5 years). There was no significant difference in age for the 3 groups. All brain images were uniformly aligned and then reformatted and resampled to yield isotropic voxels. RESULTS: Gray matter volume of the left planum temporale differed among the 3 groups. The patients with schizophrenia had significantly smaller left planum temporale volume than controls (20.0%) and patients with mania (20.0%). Heschl gyrus gray matter volume (left and right) was also reduced in patients with schizophrenia compared with controls (13.1%) and patients with bipolar mania (16.8%). CONCLUSIONS: Compared with controls and patients with bipolar manic psychosis, patients with first-episode schizophrenia showed left planum temporale gray matter volume reduction and bilateral Heschl gyrus gray matter volume reduction. These findings are similar to those reported in patients with chronic schizophrenia and suggest that such abnormalities are present at first episode and are specific to schizophrenia.  (+info)

Episodic memory in left temporal lobe epilepsy: a functional MRI study. (3/246)

Left medial temporal lobe epilepsy (MTLE) is associated with verbal memory impairment usually related to hippocampal damage. We used functional MRI (fMRI) to investigate the patterns of functional activity in healthy volunteers and MTLE patients engaged in verbal episodic memory tasks to look for evidence of a reallocation of verbal memory in epileptic patients. fMRI data were collected from seven MTLE patients with left-sided hippocampal sclerosis and 10 healthy right-handed control subjects on a 3T scanner. Subjects were instructed to learn a list of 17 words (encoding) and then to recall them (retrieval) on successive trials. Healthy volunteers and patients both exhibited bilateral activation (right higher than left) of the parahippocampal gyrus during the retrieval. This effect was more marked in the control subjects. In contrast to the control subjects, patients exhibited consistent and extensive left prefrontal activations in all the memory tasks. These findings show that verbal memory tasks did not involve the same functional patterns in patients and healthy volunteers. This may be interpreted as a dysfunctional response due to the epilepsy and left hippocampal sclerosis, and could reflect the early onset and progressive course of the disease.  (+info)

Selection of currently relevant memories by the human posterior medial orbitofrontal cortex. (4/246)

We have demonstrated previously that patients producing spontaneous confabulations fail to suppress currently irrelevant memory traces, so that they act and think on the basis of a false, temporally displaced (past) reality. All spontaneous confabulators had anterior limbic damage, in particular of the orbitofrontal cortex and basal forebrain. These findings indicated that these structures are essential for distinguishing between mental representations of ongoing reality and currently irrelevant memories. In the present study, we used a similar experimental paradigm as in our clinical studies and H(2)(15)O positron emission tomography to explore the selection of currently relevant memories by the healthy human brain. Subjects were repeatedly presented with the same set of pictures, arranged in different order each time, and were requested to indicate picture recurrences within the runs. Thus, performance in the first run depended on new learning, whereas subsequent runs required the distinction between picture repetitions within the current run ("now") and previous picture presentations in earlier runs. Whereas initial learning activated medial temporal structures, subsequent runs provoked circumscribed posterior medial orbitofrontal activation. We suggest that this area is essential for sorting out mental associations that pertain to ongoing reality.  (+info)

Lesions affecting the parahippocampal cortex yield spatial memory deficits in humans. (5/246)

Anatomical studies in monkeys, and functional imaging and lesion studies in humans, suggest that, within the primate medial temporal neocortex, the parahippocampal cortex (PHC) is particularly involved in spatial tasks. However, evidence for a functional specialization of the PHC regarding its spatial memory functions has so far been lacking. Here, we investigated spatial memory functions of the human perirhinal cortex (PRC) and PHC. Patients with lesions affecting the PRC but sparing the PHC, and patients with lesions affecting both PRC and PHC, performed an oculomotor delayed response task with unpredictably varied memory delays of up to 30 s. Compared to controls, patients with PRC+PHC lesions showed a significant delay-dependent inaccuracy of memory-guided eye movements contralateral to the lesion side, whereas patients with PRC lesions showed no significant inaccuracy. Our results show that the PHC is a critical component for spatial memory in humans and suggest that (i) extrahippocampal spatial memory functions of the medial temporal lobe may not be equally distributed in the medial temporal neocortex, but may be largely confined to the PHC, and (ii) damage to connections between cortices involved in spatial cognition and rostral regions of the temporal lobe is unlikely to account for the observed spatial memory deficits with PHC lesions.  (+info)

Perception and recognition memory in monkeys following lesions of area TE and perirhinal cortex. (6/246)

Monkeys with lesions of perirhinal cortex (PR group) and monkeys with lesions of inferotemporal cortical area TE (TE group) were tested on a modified version of the delayed nonmatching to sample (DNMS) task that included very short delay intervals (0.5 sec) as well as longer delay intervals (1 min and 10 min). Lesions of the perirhinal cortex and lesions of area TE produced different patterns of impairment. The PR group learned the DNMS task as quickly as normal monkeys (N) when the delay between sample and choice was very short (0.5 sec). However, performance of the PR group, unlike that of the N group, fell to chance levels when the delay between sample and choice was lengthened to 10 min. In contrast to the PR group, the TE group was markedly impaired on the DNMS task even at the 0.5-sec delay, and three of four monkeys with TE lesions failed to acquire the task. The results provide support for the idea that perirhinal cortex is important not for perceptual processing, but for the formation and maintenance of long-term memory. Area TE is important for the perceptual processing of visual stimuli.  (+info)

Instability in the place field location of hippocampal place cells after lesions centered on the perirhinal cortex. (7/246)

The perirhinal cortex appears to play a key role in memory, and the neighboring hippocampus is critically involved in spatial processing. The possibility exists, therefore, that perirhinal-hippocampal interactions are important for spatial memory processes. The purpose of the present study was to investigate the contribution of the perirhinal cortex to the location-specific firing ("place field") of hippocampal complex-spike ("place") cells. The firing characteristics of dorsal CA1 place cells were examined in rats with bilateral ibotenic acid lesions centered on the perirhinal cortex (n = 4) or control surgeries (n = 5) as they foraged in a rectangular environment. The activity of individual place cells was also monitored after a delay period of either 2 min, or 1 or 24 hr, during which time the animal was removed from the environment. Although the perirhinal cortex lesion did not affect the place field size or place cell firing characteristics during a recording session, it was determined that the location of the place field shifted position across the delay period in 36% (10 of 28) of the cells recorded from lesioned animals. In contrast, none of the place cells (0 of 29) recorded from control animals were unstable by this measure. These data indicate that although the initial formation of place fields in the hippocampus is not dependent on perirhinal cortex, the maintenance of this stability over time is disrupted by perirhinal lesions. This instability may represent an erroneous "re-mapping" of the environment and suggests a role for the perirhinal cortex in spatial memory processing.  (+info)

Functional plasticity of language-related brain areas after cochlear implantation. (8/246)

Using PET, the cerebral network engaged by heard language processing in normal hearing subjects was compared with that in patients who received a cochlear implant after a period of profound deafness. The experimental conditions were words, syllables and environmental sounds, each controlled by a noise baseline. Four categories of effect were observed: (i) regions that were recruited by patients and controls under identical task conditions: the left and right superior temporal cortices and the left insula were activated in both groups in all conditions; (ii) new regions, which were recruited by patients only: the left dorsal occipital cortex showed systematic activation in all conditions versus noise baselines; (iii) regions that were recruited by both groups with a different functional specificity; e.g. Wernicke's area responded specifically to speech sounds in controls but was not specialized in patients; and (iv) regions that were activated in one group more than the other: the precuneus and parahippocampal gyrus (patients more than controls) and the left inferior frontal, left posterior inferior temporal and left and right temporoparietal junction regions (controls more than patients). These data provide evidence for altered functional specificity of the superior temporal cortex, flexible recruitment of brain regions located within and outside the classical language areas and automatic contribution of visual regions to sound recognition in implant patients.  (+info)

The parahippocampal gyrus is a region within the brain's temporal lobe that plays a significant role in memory encoding and retrieval, as well as in the processing of spatial navigation and visual perception. It is located next to the hippocampus, which is another crucial structure for long-term memory formation. The parahippocampal gyrus contains several subregions, including the entorhinal cortex, perirhinal cortex, and the posterior cingulate cortex, all of which contribute to various aspects of learning and memory. Damage to this area can lead to memory impairments, particularly in the context of recognizing places or objects (source: Nieuwenhuis & De Dreu, 2016).

The temporal lobe is one of the four main lobes of the cerebral cortex in the brain, located on each side of the head roughly level with the ears. It plays a major role in auditory processing, memory, and emotion. The temporal lobe contains several key structures including the primary auditory cortex, which is responsible for analyzing sounds, and the hippocampus, which is crucial for forming new memories. Damage to the temporal lobe can result in various neurological symptoms such as hearing loss, memory impairment, and changes in emotional behavior.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Brain mapping is a broad term that refers to the techniques used to understand the structure and function of the brain. It involves creating maps of the various cognitive, emotional, and behavioral processes in the brain by correlating these processes with physical locations or activities within the nervous system. Brain mapping can be accomplished through a variety of methods, including functional magnetic resonance imaging (fMRI), positron emission tomography (PET) scans, electroencephalography (EEG), and others. These techniques allow researchers to observe which areas of the brain are active during different tasks or thoughts, helping to shed light on how the brain processes information and contributes to our experiences and behaviors. Brain mapping is an important area of research in neuroscience, with potential applications in the diagnosis and treatment of neurological and psychiatric disorders.

The dentate gyrus is a region of the brain that is located in the hippocampal formation, which is a part of the limbic system and plays a crucial role in learning, memory, and spatial navigation. It is characterized by the presence of densely packed granule cells, which are a type of neuron. The dentate gyrus is involved in the formation of new memories and the integration of information from different brain regions. It is also one of the few areas of the adult brain where new neurons can be generated throughout life, a process known as neurogenesis. Damage to the dentate gyrus has been linked to memory impairments, cognitive decline, and neurological disorders such as Alzheimer's disease and epilepsy.

Computer-assisted image processing is a medical term that refers to the use of computer systems and specialized software to improve, analyze, and interpret medical images obtained through various imaging techniques such as X-ray, CT (computed tomography), MRI (magnetic resonance imaging), ultrasound, and others.

The process typically involves several steps, including image acquisition, enhancement, segmentation, restoration, and analysis. Image processing algorithms can be used to enhance the quality of medical images by adjusting contrast, brightness, and sharpness, as well as removing noise and artifacts that may interfere with accurate diagnosis. Segmentation techniques can be used to isolate specific regions or structures of interest within an image, allowing for more detailed analysis.

Computer-assisted image processing has numerous applications in medical imaging, including detection and characterization of lesions, tumors, and other abnormalities; assessment of organ function and morphology; and guidance of interventional procedures such as biopsies and surgeries. By automating and standardizing image analysis tasks, computer-assisted image processing can help to improve diagnostic accuracy, efficiency, and consistency, while reducing the potential for human error.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

The hippocampus is a complex, curved formation in the brain that resembles a seahorse (hence its name, from the Greek word "hippos" meaning horse and "kampos" meaning sea monster). It's part of the limbic system and plays crucial roles in the formation of memories, particularly long-term ones.

This region is involved in spatial navigation and cognitive maps, allowing us to recognize locations and remember how to get to them. Additionally, it's one of the first areas affected by Alzheimer's disease, which often results in memory loss as an early symptom.

Anatomically, it consists of two main parts: the Ammon's horn (or cornu ammonis) and the dentate gyrus. These structures are made up of distinct types of neurons that contribute to different aspects of learning and memory.

In the context of medical and clinical neuroscience, memory is defined as the brain's ability to encode, store, retain, and recall information or experiences. Memory is a complex cognitive process that involves several interconnected regions of the brain and can be categorized into different types based on various factors such as duration and the nature of the information being remembered.

The major types of memory include:

1. Sensory memory: The shortest form of memory, responsible for holding incoming sensory information for a brief period (less than a second to several seconds) before it is either transferred to short-term memory or discarded.
2. Short-term memory (also called working memory): A temporary storage system that allows the brain to hold and manipulate information for approximately 20-30 seconds, although this duration can be extended through rehearsal strategies. Short-term memory has a limited capacity, typically thought to be around 7±2 items.
3. Long-term memory: The memory system responsible for storing large amounts of information over extended periods, ranging from minutes to a lifetime. Long-term memory has a much larger capacity compared to short-term memory and is divided into two main categories: explicit (declarative) memory and implicit (non-declarative) memory.

Explicit (declarative) memory can be further divided into episodic memory, which involves the recollection of specific events or episodes, including their temporal and spatial contexts, and semantic memory, which refers to the storage and retrieval of general knowledge, facts, concepts, and vocabulary, independent of personal experience or context.

Implicit (non-declarative) memory encompasses various forms of learning that do not require conscious awareness or intention, such as procedural memory (skills and habits), priming (facilitated processing of related stimuli), classical conditioning (associative learning), and habituation (reduced responsiveness to repeated stimuli).

Memory is a crucial aspect of human cognition and plays a significant role in various aspects of daily life, including learning, problem-solving, decision-making, social interactions, and personal identity. Memory dysfunction can result from various neurological and psychiatric conditions, such as dementia, Alzheimer's disease, stroke, traumatic brain injury, and depression.

The limbic system is a complex set of structures in the brain that includes the hippocampus, amygdala, fornix, cingulate gyrus, and other nearby areas. It's associated with emotional responses, instinctual behaviors, motivation, long-term memory formation, and olfaction (smell). The limbic system is also involved in the modulation of visceral functions and drives, such as hunger, thirst, and sexual drive.

The structures within the limbic system communicate with each other and with other parts of the brain, particularly the hypothalamus and the cortex, to regulate various physiological and psychological processes. Dysfunctions in the limbic system can lead to a range of neurological and psychiatric conditions, including depression, anxiety disorders, post-traumatic stress disorder (PTSD), and certain types of memory impairment.

The cerebral cortex is the outermost layer of the brain, characterized by its intricate folded structure and wrinkled appearance. It is a region of great importance as it plays a key role in higher cognitive functions such as perception, consciousness, thought, memory, language, and attention. The cerebral cortex is divided into two hemispheres, each containing four lobes: the frontal, parietal, temporal, and occipital lobes. These areas are responsible for different functions, with some regions specializing in sensory processing while others are involved in motor control or associative functions. The cerebral cortex is composed of gray matter, which contains neuronal cell bodies, and is covered by a layer of white matter that consists mainly of myelinated nerve fibers.

Neuropsychological tests are a type of psychological assessment that measures cognitive functions, such as attention, memory, language, problem-solving, and perception. These tests are used to help diagnose and understand the cognitive impact of neurological conditions, including dementia, traumatic brain injury, stroke, Parkinson's disease, and other disorders that affect the brain.

The tests are typically administered by a trained neuropsychologist and can take several hours to complete. They may involve paper-and-pencil tasks, computerized tasks, or interactive activities. The results of the tests are compared to normative data to help identify any areas of cognitive weakness or strength.

Neuropsychological testing can provide valuable information for treatment planning, rehabilitation, and assessing response to treatment. It can also be used in research to better understand the neural basis of cognition and the impact of neurological conditions on cognitive function.

Temporal lobe epilepsy (TLE) is a type of focal (localized) epilepsy that originates from the temporal lobes of the brain. The temporal lobes are located on each side of the brain and are involved in processing sensory information, memory, and emotion. TLE is characterized by recurrent seizures that originate from one or both temporal lobes.

The symptoms of TLE can vary depending on the specific area of the temporal lobe that is affected. However, common symptoms include auras (sensory or emotional experiences that occur before a seizure), strange smells or tastes, lip-smacking or chewing movements, and memory problems. Some people with TLE may also experience automatisms (involuntary movements such as picking at clothes or fumbling with objects) during their seizures.

Treatment for TLE typically involves medication to control seizures, although surgery may be recommended in some cases. The goal of treatment is to reduce the frequency and severity of seizures and improve quality of life.

Atrophy is a medical term that refers to the decrease in size and wasting of an organ or tissue due to the disappearance of cells, shrinkage of cells, or decreased number of cells. This process can be caused by various factors such as disuse, aging, degeneration, injury, or disease.

For example, if a muscle is immobilized for an extended period, it may undergo atrophy due to lack of use. Similarly, certain medical conditions like diabetes, cancer, and heart failure can lead to the wasting away of various tissues and organs in the body.

Atrophy can also occur as a result of natural aging processes, leading to decreased muscle mass and strength in older adults. In general, atrophy is characterized by a decrease in the volume or weight of an organ or tissue, which can have significant impacts on its function and overall health.

The mamillary bodies are a pair of small, round structures located in the hypothalamus region of the brain. They play a crucial role in the limbic system, which is involved in emotions, memory, and learning. Specifically, the mamillary bodies are part of the circuit that forms the Papez circuit, a neural network responsible for memory and cognitive functions.

The mamillary bodies receive inputs from several brain regions, including the hippocampus, anterior thalamic nuclei, and cingulate gyrus. They then project this information to the thalamus, which in turn sends it to the cerebral cortex for further processing.

Damage to the mamillary bodies can result in memory impairment, as seen in patients with Korsakoff's syndrome, a condition often associated with chronic alcohol abuse.

Photic stimulation is a medical term that refers to the exposure of the eyes to light, specifically repetitive pulses of light, which is used as a method in various research and clinical settings. In neuroscience, it's often used in studies related to vision, circadian rhythms, and brain function.

In a clinical context, photic stimulation is sometimes used in the diagnosis of certain medical conditions such as seizure disorders (like epilepsy). By observing the response of the brain to this light stimulus, doctors can gain valuable insights into the functioning of the brain and the presence of any neurological disorders.

However, it's important to note that photic stimulation should be conducted under the supervision of a trained healthcare professional, as improper use can potentially trigger seizures in individuals who are susceptible to them.

Memory disorders are a category of cognitive impairments that affect an individual's ability to acquire, store, retain, and retrieve memories. These disorders can be caused by various underlying medical conditions, including neurological disorders, psychiatric illnesses, substance abuse, or even normal aging processes. Some common memory disorders include:

1. Alzheimer's disease: A progressive neurodegenerative disorder that primarily affects older adults and is characterized by a decline in cognitive abilities, including memory, language, problem-solving, and decision-making skills.
2. Dementia: A broader term used to describe a group of symptoms associated with a decline in cognitive function severe enough to interfere with daily life. Alzheimer's disease is the most common cause of dementia, but other causes include vascular dementia, Lewy body dementia, and frontotemporal dementia.
3. Amnesia: A memory disorder characterized by difficulties in forming new memories or recalling previously learned information due to brain damage or disease. Amnesia can be temporary or permanent and may result from head trauma, stroke, infection, or substance abuse.
4. Mild cognitive impairment (MCI): A condition where an individual experiences mild but noticeable memory or cognitive difficulties that are greater than expected for their age and education level. While some individuals with MCI may progress to dementia, others may remain stable or even improve over time.
5. Korsakoff's syndrome: A memory disorder often caused by alcohol abuse and thiamine deficiency, characterized by severe short-term memory loss, confabulation (making up stories to fill in memory gaps), and disorientation.

It is essential to consult a healthcare professional if you or someone you know experiences persistent memory difficulties, as early diagnosis and intervention can help manage symptoms and improve quality of life.

Functional laterality, in a medical context, refers to the preferential use or performance of one side of the body over the other for specific functions. This is often demonstrated in hand dominance, where an individual may be right-handed or left-handed, meaning they primarily use their right or left hand for tasks such as writing, eating, or throwing.

However, functional laterality can also apply to other bodily functions and structures, including the eyes (ocular dominance), ears (auditory dominance), or legs. It's important to note that functional laterality is not a strict binary concept; some individuals may exhibit mixed dominance or no strong preference for one side over the other.

In clinical settings, assessing functional laterality can be useful in diagnosing and treating various neurological conditions, such as stroke or traumatic brain injury, where understanding any resulting lateralized impairments can inform rehabilitation strategies.

The occipital lobe is the portion of the cerebral cortex that lies at the back of the brain (posteriorly) and is primarily involved in visual processing. It contains areas that are responsible for the interpretation and integration of visual stimuli, including color, form, movement, and recognition of objects. The occipital lobe is divided into several regions, such as the primary visual cortex (V1), secondary visual cortex (V2 to V5), and the visual association cortex, which work together to process different aspects of visual information. Damage to the occipital lobe can lead to various visual deficits, including blindness or partial loss of vision, known as a visual field cut.

Visual pattern recognition is the ability to identify and interpret patterns in visual information. In a medical context, it often refers to the process by which healthcare professionals recognize and diagnose medical conditions based on visible signs or symptoms. This can involve recognizing the characteristic appearance of a rash, wound, or other physical feature associated with a particular disease or condition. It may also involve recognizing patterns in medical images such as X-rays, CT scans, or MRIs.

In the field of radiology, for example, visual pattern recognition is a critical skill. Radiologists are trained to recognize the typical appearances of various diseases and conditions in medical images. This allows them to make accurate diagnoses based on the patterns they see. Similarly, dermatologists use visual pattern recognition to identify skin abnormalities and diseases based on the appearance of rashes, lesions, or other skin changes.

Overall, visual pattern recognition is an essential skill in many areas of medicine, allowing healthcare professionals to quickly and accurately diagnose medical conditions based on visible signs and symptoms.

Cerebral dominance is a concept in neuropsychology that refers to the specialization of one hemisphere of the brain over the other for certain cognitive functions. In most people, the left hemisphere is dominant for language functions such as speaking and understanding spoken or written language, while the right hemisphere is dominant for non-verbal functions such as spatial ability, face recognition, and artistic ability.

Cerebral dominance does not mean that the non-dominant hemisphere is incapable of performing the functions of the dominant hemisphere, but rather that it is less efficient or specialized in those areas. The concept of cerebral dominance has been used to explain individual differences in cognitive abilities and learning styles, as well as the laterality of brain damage and its effects on cognition and behavior.

It's important to note that cerebral dominance is a complex phenomenon that can vary between individuals and can be influenced by various factors such as genetics, environment, and experience. Additionally, recent research has challenged the strict lateralization of functions and suggested that there is more functional overlap and interaction between the two hemispheres than previously thought.

The frontal lobe is the largest lobes of the human brain, located at the front part of each cerebral hemisphere and situated in front of the parietal and temporal lobes. It plays a crucial role in higher cognitive functions such as decision making, problem solving, planning, parts of social behavior, emotional expressions, physical reactions, and motor function. The frontal lobe is also responsible for what's known as "executive functions," which include the ability to focus attention, understand rules, switch focus, plan actions, and inhibit inappropriate behaviors. It is divided into five areas, each with its own specific functions: the primary motor cortex, premotor cortex, Broca's area, prefrontal cortex, and orbitofrontal cortex. Damage to the frontal lobe can result in a wide range of impairments, depending on the location and extent of the injury.

Neural pathways, also known as nerve tracts or fasciculi, refer to the highly organized and specialized routes through which nerve impulses travel within the nervous system. These pathways are formed by groups of neurons (nerve cells) that are connected in a series, creating a continuous communication network for electrical signals to transmit information between different regions of the brain, spinal cord, and peripheral nerves.

Neural pathways can be classified into two main types: sensory (afferent) and motor (efferent). Sensory neural pathways carry sensory information from various receptors in the body (such as those for touch, temperature, pain, and vision) to the brain for processing. Motor neural pathways, on the other hand, transmit signals from the brain to the muscles and glands, controlling movements and other effector functions.

The formation of these neural pathways is crucial for normal nervous system function, as it enables efficient communication between different parts of the body and allows for complex behaviors, cognitive processes, and adaptive responses to internal and external stimuli.

The prefrontal cortex is the anterior (frontal) part of the frontal lobe in the brain, involved in higher-order cognitive processes such as planning complex cognitive behavior, personality expression, decision making, and moderating social behavior. It also plays a significant role in working memory and executive functions. The prefrontal cortex is divided into several subregions, each associated with specific cognitive and emotional functions. Damage to the prefrontal cortex can result in various impairments, including difficulties with planning, decision making, and social behavior regulation.

A nerve net, also known as a neural net or neuronal network, is not a medical term per se, but rather a concept in neuroscience and artificial intelligence (AI). It refers to a complex network of interconnected neurons that process and transmit information. In the context of the human body, the nervous system can be thought of as a type of nerve net, with the brain and spinal cord serving as the central processing unit and peripheral nerves carrying signals to and from various parts of the body.

In the field of AI, artificial neural networks are computational models inspired by the structure and function of biological nerve nets. These models consist of interconnected nodes or "neurons" that process information and learn patterns through a process of training and adaptation. They have been used in a variety of applications, including image recognition, natural language processing, and machine learning.

Alzheimer's disease is a progressive disorder that causes brain cells to waste away (degenerate) and die. It's the most common cause of dementia — a continuous decline in thinking, behavioral and social skills that disrupts a person's ability to function independently.

The early signs of the disease include forgetting recent events or conversations. As the disease progresses, a person with Alzheimer's disease will develop severe memory impairment and lose the ability to carry out everyday tasks.

Currently, there's no cure for Alzheimer's disease. However, treatments can temporarily slow the worsening of dementia symptoms and improve quality of life.

"Mental recall," also known as "memory recall," refers to the ability to retrieve or bring information from your memory storage into your conscious mind, so you can think about, use, or apply it. This process involves accessing and retrieving stored memories in response to certain cues or prompts. It is a fundamental cognitive function that allows individuals to remember and recognize people, places, events, facts, and experiences.

In the context of medical terminology, mental recall may be used to assess an individual's cognitive abilities, particularly in relation to memory function. Impairments in memory recall can be indicative of various neurological or psychological conditions, such as dementia, Alzheimer's disease, or amnesia.

The entorhinal cortex is a region in the brain that is located in the medial temporal lobe and is part of the limbic system. It plays a crucial role in memory, navigation, and the processing of sensory information. The entorhinal cortex is closely connected to the hippocampus, which is another important structure for memory and spatial cognition.

The entorhinal cortex can be divided into several subregions, including the lateral, medial, and posterior sections. These subregions have distinct connectivity patterns and may contribute differently to various cognitive functions. One of the most well-known features of the entorhinal cortex is the presence of "grid cells," which are neurons that fire in response to specific spatial locations and help to form a cognitive map of the environment.

Damage to the entorhinal cortex has been linked to several neurological and psychiatric conditions, including Alzheimer's disease, epilepsy, and schizophrenia.

The parietal lobe is a region of the brain that is located in the posterior part of the cerebral cortex, covering the upper and rear portions of the brain. It is involved in processing sensory information from the body, such as touch, temperature, and pain, as well as spatial awareness and perception, visual-spatial cognition, and the integration of different senses.

The parietal lobe can be divided into several functional areas, including the primary somatosensory cortex (which receives tactile information from the body), the secondary somatosensory cortex (which processes more complex tactile information), and the posterior parietal cortex (which is involved in spatial attention, perception, and motor planning).

Damage to the parietal lobe can result in various neurological symptoms, such as neglect of one side of the body, difficulty with spatial orientation, problems with hand-eye coordination, and impaired mathematical and language abilities.

Visual perception refers to the ability to interpret and organize information that comes from our eyes to recognize and understand what we are seeing. It involves several cognitive processes such as pattern recognition, size estimation, movement detection, and depth perception. Visual perception allows us to identify objects, navigate through space, and interact with our environment. Deficits in visual perception can lead to learning difficulties and disabilities.

The gyrus cinguli, also known as the cingulate gyrus, is a structure located in the brain. It forms part of the limbic system and plays a role in various functions such as emotion, memory, and perception of pain. The gyrus cinguli is situated in the medial aspect of the cerebral hemisphere, adjacent to the corpus callosum, and curves around the frontal portion of the corpus callosum, forming a C-shaped structure. It has been implicated in several neurological and psychiatric conditions, including depression, anxiety disorders, and chronic pain syndromes.

Schizophrenia is a severe mental disorder characterized by disturbances in thought, perception, emotion, and behavior. It often includes hallucinations (usually hearing voices), delusions, paranoia, and disorganized speech and behavior. The onset of symptoms typically occurs in late adolescence or early adulthood. Schizophrenia is a complex, chronic condition that requires ongoing treatment and management. It significantly impairs social and occupational functioning, and it's often associated with reduced life expectancy due to comorbid medical conditions. The exact causes of schizophrenia are not fully understood, but research suggests that genetic, environmental, and neurodevelopmental factors play a role in its development.

The amygdala is an almond-shaped group of nuclei located deep within the temporal lobe of the brain, specifically in the anterior portion of the temporal lobes and near the hippocampus. It forms a key component of the limbic system and plays a crucial role in processing emotions, particularly fear and anxiety. The amygdala is involved in the integration of sensory information with emotional responses, memory formation, and decision-making processes.

In response to emotionally charged stimuli, the amygdala can modulate various physiological functions, such as heart rate, blood pressure, and stress hormone release, via its connections to the hypothalamus and brainstem. Additionally, it contributes to social behaviors, including recognizing emotional facial expressions and responding appropriately to social cues. Dysfunctions in amygdala function have been implicated in several psychiatric and neurological conditions, such as anxiety disorders, depression, post-traumatic stress disorder (PTSD), and autism spectrum disorder (ASD).

Oxygen is a colorless, odorless, tasteless gas that constitutes about 21% of the earth's atmosphere. It is a crucial element for human and most living organisms as it is vital for respiration. Inhaled oxygen enters the lungs and binds to hemoglobin in red blood cells, which carries it to tissues throughout the body where it is used to convert nutrients into energy and carbon dioxide, a waste product that is exhaled.

Medically, supplemental oxygen therapy may be provided to patients with conditions such as chronic obstructive pulmonary disease (COPD), pneumonia, heart failure, or other medical conditions that impair the body's ability to extract sufficient oxygen from the air. Oxygen can be administered through various devices, including nasal cannulas, face masks, and ventilators.

Reaction time, in the context of medicine and physiology, refers to the time period between the presentation of a stimulus and the subsequent initiation of a response. This complex process involves the central nervous system, particularly the brain, which perceives the stimulus, processes it, and then sends signals to the appropriate muscles or glands to react.

There are different types of reaction times, including simple reaction time (responding to a single, expected stimulus) and choice reaction time (choosing an appropriate response from multiple possibilities). These measures can be used in clinical settings to assess various aspects of neurological function, such as cognitive processing speed, motor control, and alertness.

However, it is important to note that reaction times can be influenced by several factors, including age, fatigue, attention, and the use of certain medications or substances.

Emotions are complex psychological states that involve three distinct components: a subjective experience, a physiological response, and a behavioral or expressive response. Emotions can be short-lived, such as a flash of anger, or more long-lasting, such as enduring sadness. They can also vary in intensity, from mild irritation to intense joy or fear.

Emotions are often distinguished from other psychological states, such as moods and temperament, which may be less specific and more enduring. Emotions are typically thought to have a clear cause or object, such as feeling happy when you receive good news or feeling anxious before a job interview.

There are many different emotions that people can experience, including happiness, sadness, anger, fear, surprise, disgust, and shame. These emotions are often thought to serve important adaptive functions, helping individuals respond to challenges and opportunities in their environment.

In medical contexts, emotions may be relevant to the diagnosis and treatment of various mental health conditions, such as depression, anxiety disorders, and bipolar disorder. Abnormalities in emotional processing and regulation have been implicated in many psychiatric illnesses, and therapies that target these processes may be effective in treating these conditions.

In medical terms, "association" is a relationship between two or more variables, conditions, or factors in which they consistently occur together more often than would be expected by chance. This does not necessarily mean that one causes the other, but simply that they are connected in some way. The association can be positive (meaning that as one variable increases, so does the other) or negative (meaning that as one variable increases, the other decreases).

For example, there is a well-known association between smoking and lung cancer, meaning that people who smoke are more likely to develop lung cancer than those who do not. However, this does not mean that smoking causes lung cancer, only that the two are linked in some way. Further research is needed to establish causality.

Positron-Emission Tomography (PET) is a type of nuclear medicine imaging that uses small amounts of radioactive material, called a radiotracer, to produce detailed, three-dimensional images. This technique measures metabolic activity within the body, such as sugar metabolism, to help distinguish between healthy and diseased tissue, identify cancerous cells, or examine the function of organs.

During a PET scan, the patient is injected with a radiotracer, typically a sugar-based compound labeled with a positron-emitting radioisotope, such as fluorine-18 (^18^F). The radiotracer accumulates in cells that are metabolically active, like cancer cells. As the radiotracer decays, it emits positrons, which then collide with electrons in nearby tissue, producing gamma rays. A special camera, called a PET scanner, detects these gamma rays and uses this information to create detailed images of the body's internal structures and processes.

PET is often used in conjunction with computed tomography (CT) or magnetic resonance imaging (MRI) to provide both functional and anatomical information, allowing for more accurate diagnosis and treatment planning. Common applications include detecting cancer recurrence, staging and monitoring cancer, evaluating heart function, and assessing brain function in conditions like dementia and epilepsy.

Analysis of Variance (ANOVA) is a statistical technique used to compare the means of two or more groups and determine whether there are any significant differences between them. It is a way to analyze the variance in a dataset to determine whether the variability between groups is greater than the variability within groups, which can indicate that the groups are significantly different from one another.

ANOVA is based on the concept of partitioning the total variance in a dataset into two components: variance due to differences between group means (also known as "between-group variance") and variance due to differences within each group (also known as "within-group variance"). By comparing these two sources of variance, ANOVA can help researchers determine whether any observed differences between groups are statistically significant, or whether they could have occurred by chance.

ANOVA is a widely used technique in many areas of research, including biology, psychology, engineering, and business. It is often used to compare the means of two or more experimental groups, such as a treatment group and a control group, to determine whether the treatment had a significant effect. ANOVA can also be used to compare the means of different populations or subgroups within a population, to identify any differences that may exist between them.

In medical terms, the face refers to the front part of the head that is distinguished by the presence of the eyes, nose, and mouth. It includes the bones of the skull (frontal bone, maxilla, zygoma, nasal bones, lacrimal bones, palatine bones, inferior nasal conchae, and mandible), muscles, nerves, blood vessels, skin, and other soft tissues. The face plays a crucial role in various functions such as breathing, eating, drinking, speaking, seeing, smelling, and expressing emotions. It also serves as an important identifier for individuals, allowing them to be recognized by others.

Emission computed tomography (ECT) is a type of tomographic imaging technique in which an emission signal from within the body is detected to create cross-sectional images of that signal's distribution. In Emission-Computed Tomography (ECT), a radionuclide is introduced into the body, usually through injection, inhalation or ingestion. The radionuclide emits gamma rays that are then detected by external gamma cameras.

The data collected from these cameras is then used to create cross-sectional images of the distribution of the radiopharmaceutical within the body. This allows for the identification and quantification of functional information about specific organs or systems within the body, such as blood flow, metabolic activity, or receptor density.

One common type of Emission-Computed Tomography is Single Photon Emission Computed Tomography (SPECT), which uses a single gamma camera that rotates around the patient to collect data from multiple angles. Another type is Positron Emission Tomography (PET), which uses positron-emitting radionuclides and detects the coincident gamma rays emitted by the annihilation of positrons and electrons.

Overall, ECT is a valuable tool in medical imaging for diagnosing and monitoring various diseases, including cancer, heart disease, and neurological disorders.

Space perception, in the context of neuroscience and psychology, refers to the ability to perceive and understand the spatial arrangement of objects and their relationship to oneself. It involves integrating various sensory inputs such as visual, auditory, tactile, and proprioceptive information to create a coherent three-dimensional representation of our environment.

This cognitive process enables us to judge distances, sizes, shapes, and movements of objects around us. It also helps us navigate through space, reach for objects, avoid obstacles, and maintain balance. Disorders in space perception can lead to difficulties in performing everyday activities and may be associated with neurological conditions such as stroke, brain injury, or neurodevelopmental disorders like autism.

A case-control study is an observational research design used to identify risk factors or causes of a disease or health outcome. In this type of study, individuals with the disease or condition (cases) are compared with similar individuals who do not have the disease or condition (controls). The exposure history or other characteristics of interest are then compared between the two groups to determine if there is an association between the exposure and the disease.

Case-control studies are often used when it is not feasible or ethical to conduct a randomized controlled trial, as they can provide valuable insights into potential causes of diseases or health outcomes in a relatively short period of time and at a lower cost than other study designs. However, because case-control studies rely on retrospective data collection, they are subject to biases such as recall bias and selection bias, which can affect the validity of the results. Therefore, it is important to carefully design and conduct case-control studies to minimize these potential sources of bias.

Cognition refers to the mental processes involved in acquiring, processing, and utilizing information. These processes include perception, attention, memory, language, problem-solving, and decision-making. Cognitive functions allow us to interact with our environment, understand and respond to stimuli, learn new skills, and remember experiences.

In a medical context, cognitive function is often assessed as part of a neurological or psychiatric evaluation. Impairments in cognition can be caused by various factors, such as brain injury, neurodegenerative diseases (e.g., Alzheimer's disease), infections, toxins, and mental health conditions. Assessing cognitive function helps healthcare professionals diagnose conditions, monitor disease progression, and develop treatment plans.

Three-dimensional (3D) imaging in medicine refers to the use of technologies and techniques that generate a 3D representation of internal body structures, organs, or tissues. This is achieved by acquiring and processing data from various imaging modalities such as X-ray computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, or confocal microscopy. The resulting 3D images offer a more detailed visualization of the anatomy and pathology compared to traditional 2D imaging techniques, allowing for improved diagnostic accuracy, surgical planning, and minimally invasive interventions.

In 3D imaging, specialized software is used to reconstruct the acquired data into a volumetric model, which can be manipulated and viewed from different angles and perspectives. This enables healthcare professionals to better understand complex anatomical relationships, detect abnormalities, assess disease progression, and monitor treatment response. Common applications of 3D imaging include neuroimaging, orthopedic surgery planning, cancer staging, dental and maxillofacial reconstruction, and interventional radiology procedures.

Cognitive disorders are a category of mental health disorders that primarily affect cognitive abilities including learning, memory, perception, and problem-solving. These disorders can be caused by various factors such as brain injury, degenerative diseases, infection, substance abuse, or developmental disabilities. Examples of cognitive disorders include dementia, amnesia, delirium, and intellectual disability. It's important to note that the specific definition and diagnostic criteria for cognitive disorders may vary depending on the medical source or classification system being used.

The fornix, in the context of brain anatomy, is a bundle of nerve fibers that arises from the hippocampus, a major component of the limbic system associated with memory and spatial navigation. The fornix plays a crucial role in conveying information between different parts of the brain.

The fornix has two primary divisions: the precommissural fornix and the postcommissural fornix. The precommissural fornix contains fibers that originate from the hippocampus and the subiculum, while the postcommissural fornix consists of fibers that originate from the septal nuclei and other structures in the limbic system.

The two divisions of the fornix join together to form a structure called the body of the fornix, which then curves around the thalamus and continues as the crura (plural of crus) of the fornix. The crura split into two columns that pass through the interventricular foramen and terminate in the hypothalamus, specifically at the mammillary bodies.

The fornix is an essential structure for memory function, particularly episodic memory (memory of specific events or episodes). Damage to the fornix can result in various cognitive impairments, including memory loss and difficulties with spatial navigation.

Reference values, also known as reference ranges or reference intervals, are the set of values that are considered normal or typical for a particular population or group of people. These values are often used in laboratory tests to help interpret test results and determine whether a patient's value falls within the expected range.

The process of establishing reference values typically involves measuring a particular biomarker or parameter in a large, healthy population and then calculating the mean and standard deviation of the measurements. Based on these statistics, a range is established that includes a certain percentage of the population (often 95%) and excludes extreme outliers.

It's important to note that reference values can vary depending on factors such as age, sex, race, and other demographic characteristics. Therefore, it's essential to use reference values that are specific to the relevant population when interpreting laboratory test results. Additionally, reference values may change over time due to advances in measurement technology or changes in the population being studied.

Higher Nervous Activity (HNA) is a term used in neurology and psychology to refer to the complex functions of the nervous system that are associated with higher order cognitive processes, such as thinking, learning, memory, perception, and language. These functions are primarily mediated by the cerebral cortex and other associative areas of the brain, which are involved in integrating sensory information, planning and executing motor responses, and modulating emotional and social behavior.

HNA is often contrasted with lower nervous activity (LNA), which refers to more basic functions of the nervous system, such as reflexes and automatic responses that do not require conscious control or higher-order cognitive processing. HNA is thought to be unique to humans and some other animals, and is believed to have evolved to enable complex behaviors and adaptations to changing environments.

Disorders of HNA can result in a wide range of neurological and psychiatric symptoms, depending on the specific areas of the brain that are affected. These may include cognitive impairments, memory loss, language disorders, perceptual disturbances, emotional dysregulation, and motor deficits.

I'm sorry for any confusion, but "spatial behavior" is not a term that has a specific medical definition. It is a concept that is used in various fields, including psychology, neuroscience, and robotics, to refer to the way that organisms or machines navigate and interact with their environment based on spatial relationships and coordinates.

In a broader context, "spatial behavior" can sometimes be used to describe certain aspects of human behavior related to how people move and interact within spaces, such as in architecture, urban planning, or ergonomics. However, it is not a term that is typically used in medical diagnoses or treatments.

If you have any specific questions about a concept related to medicine or health, I would be happy to try to help answer them for you!

Episodic memory is a type of declarative (explicit) memory that involves the ability to recall and mentally reexperience specific events or episodes, including their temporal and spatial contexts. It is the memory for particular events or episodes that are embedded in a personal autobiographical timeline, along with the details of what happened, where it happened, who was involved, and when it happened. Episodic memories are often formed through conscious effort and can be voluntarily retrieved. They are susceptible to interference and decay over time, making them less reliable than other types of memory.

Amnesia is a condition characterized by memory loss, which can be temporary or permanent. It may result from brain damage or disease, and it can affect various aspects of memory, such as the ability to recall past events (retrograde amnesia), the ability to form new memories (anterograde amnesia), or both. Amnesia can also affect a person's sense of identity and their ability to learn new skills.

There are several types of amnesia, including:

1. Anterograde amnesia: This type of amnesia affects the ability to form new memories after an injury or trauma. People with anterograde amnesia may have difficulty learning new information and remembering recent events.
2. Retrograde amnesia: Retrograde amnesia affects the ability to recall memories that were formed before an injury or trauma. People with retrograde amnesia may have trouble remembering events, people, or facts from their past.
3. Transient global amnesia: This is a temporary form of amnesia that usually lasts for less than 24 hours. It is often caused by a lack of blood flow to the brain, and it can be triggered by emotional stress, physical exertion, or other factors.
4. Korsakoff's syndrome: This is a type of amnesia that is caused by alcohol abuse and malnutrition. It is characterized by severe memory loss, confusion, and disorientation.
5. Dissociative amnesia: This type of amnesia is caused by psychological factors, such as trauma or stress. People with dissociative amnesia may have trouble remembering important personal information or events that are emotionally charged.

The treatment for amnesia depends on the underlying cause. In some cases, memory may improve over time, while in other cases, it may be permanent. Treatment may involve medication, therapy, or rehabilitation to help people with amnesia cope with their memory loss and develop new skills to compensate for their memory impairments.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Diffusion Tensor Imaging (DTI) is a type of magnetic resonance imaging (MRI) technique that allows for the measurement and visualization of water diffusion in biological tissues, particularly in the brain. DTI provides information about the microstructural organization and integrity of nerve fibers within the brain by measuring the directionality of water diffusion in the brain's white matter tracts.

In DTI, a tensor is used to describe the three-dimensional diffusion properties of water molecules in each voxel (three-dimensional pixel) of an MRI image. The tensor provides information about the magnitude and direction of water diffusion, which can be used to calculate various diffusion metrics such as fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD). These metrics provide insights into the structural properties of nerve fibers, including their orientation, density, and integrity.

DTI has numerous clinical applications, such as in the diagnosis and monitoring of neurological disorders like multiple sclerosis, traumatic brain injury, and neurodegenerative diseases. It can also be used for presurgical planning to identify critical white matter tracts that need to be preserved during surgery.

Psychomotor performance refers to the integration and coordination of mental processes (cognitive functions) with physical movements. It involves the ability to perform complex tasks that require both cognitive skills, such as thinking, remembering, and perceiving, and motor skills, such as gross and fine motor movements. Examples of psychomotor performances include driving a car, playing a musical instrument, or performing surgical procedures.

In a medical context, psychomotor performance is often used to assess an individual's ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), such as bathing, dressing, cooking, cleaning, and managing medications. Deficits in psychomotor performance can be a sign of neurological or psychiatric disorders, such as dementia, Parkinson's disease, or depression.

Assessment of psychomotor performance may involve tests that measure reaction time, coordination, speed, precision, and accuracy of movements, as well as cognitive functions such as attention, memory, and problem-solving skills. These assessments can help healthcare professionals develop appropriate treatment plans and monitor the progression of diseases or the effectiveness of interventions.

Anisotropy is a medical term that refers to the property of being directionally dependent, meaning that its properties or characteristics vary depending on the direction in which they are measured. In the context of medicine and biology, anisotropy can refer to various biological structures, tissues, or materials that exhibit different physical or chemical properties along different axes.

For example, certain types of collagen fibers in tendons and ligaments exhibit anisotropic behavior because they are stronger and stiffer when loaded along their long axis compared to being loaded perpendicular to it. Similarly, some brain tissues may show anisotropy due to the presence of nerve fibers that are organized in specific directions, leading to differences in electrical conductivity or diffusion properties depending on the orientation of the measurement.

Anisotropy is an important concept in various medical fields, including radiology, neurology, and materials science, as it can provide valuable information about the structure and function of biological tissues and help guide diagnostic and therapeutic interventions.

Mild Cognitive Impairment (MCI) is a medical term used to describe a stage between the cognitive changes seen in normal aging and the more serious decline of dementia. It's characterized by a slight but noticeable decline in cognitive abilities, such as memory or thinking skills, that are greater than expected for an individual's age and education level, but not significant enough to interfere with daily life.

People with MCI have an increased risk of developing dementia, particularly Alzheimer's disease, compared to those without MCI. However, it's important to note that not everyone with MCI will develop dementia; some may remain stable, and others may even improve over time.

The diagnosis of MCI is typically made through a comprehensive medical evaluation, including a detailed medical history, cognitive testing, and sometimes brain imaging or laboratory tests.

... shown in yellow. Close up of parahippocampal gyrus. Parahippocampal gyrus, shown in right cerebral ... Parahippocampal gyrus highlighted in green on coronal T1 MRI images Parahippocampal gyrus highlighted in green on sagittal T1 ... Parahippocampal gyrus shown red. Medial surface of left cerebral hemisphere. Parahippocampal gyrus shown in orange. Human brain ... Parahippocampal gyrus labelled as #5 Coronal section. Parahippocampal gyrus labelled at bottom center. Coronal section of ...
The posterior parahippocampal gyrus is a portion of the parahippocampal gyrus. It can show deterioration in Alzheimer's disease ... Thangavel R, Van Hoesen GW, Zaheer A (June 2008). "Posterior parahippocampal gyrus pathology in Alzheimer's disease". ... v t e (Gyri, All stub articles, Neuroanatomy stubs). ...
... ; inferior temporal gyrus; parahippocampal gyrus; lingual gyrus; inferior occipital gyrus. Fusiform gyrus and ... The fusiform gyrus is located between the lingual gyrus and parahippocampal gyrus above, and the inferior temporal gyrus below ... located laterally in respect to the fusiform gyrus) and the CoS separates the fusiform gyrus from the parahippocampal gyrus ( ... located medially in respect to the fusiform gyrus). Inferior views of the fusiform gyrus Fusiform gyrus and adjacent gyri. ...
... temporalis inferior Fusiform gyrus, lat. gyrus occipitotemporalis lateralis Parahippocampal gyrus, lat. gyrus ... gyrus postcentralis Supramarginal gyrus, lat. gyrus supramarginalis Angular gyrus, lat. gyrus angularis Cingulate gyrus lat. ... Superior frontal gyrus, lat. gyrus frontalis superior Middle frontal gyrus, lat. gyrus frontalis medius Inferior frontal gyrus ... gyrus temporalis superior Middle temporal gyrus, lat. gyrus temporalis medius Inferior temporal gyrus, lat. ...
Sensory information passes from cortical areas, through the parahippocampal gyrus to the hippocampus. The parahippocampal gyrus ... Parahippocampal region The parahippocampal gyrus surrounds the hippocampus. ... The parahippocampal gyrus is activated in paired-associate prospective memory tasks, in which participants must learn a pair of ... Studies using PET have come to the same conclusions regarding the use of the parahippocampal gyrus for prospective memory. ...
The parahippocampal gyrus houses the topographical map for olfaction. The orbitofrontal cortex (OFC) is heavily correlated with ... and parahippocampal gyrus. The olfactory tubercle connects to numerous areas of the amygdala, thalamus, hypothalamus, ... the cingulate gyrus and septal area to act out positive/negative reinforcement. The OFC is the expectation of reward/punishment ...
Functional Disturbances of the Hippocampus and Its Parahippocampal Gyrus. A number of studies suggest that this region of the ... Reduced Cerebral Blood Flow in Angular Gyrus. A couple of studies found reduced cerebral blood flow in angular gyrus of ...
The uncus is an anterior extremity of the parahippocampal gyrus. It is separated from the apex of the temporal lobe by a slight ... "Cannabis-associated psychotic-like experiences are mediated by developmental changes in the parahippocampal gyrus". Journal of ... Although superficially continuous with the hippocampal gyrus, the uncus forms morphologically a part of the rhinencephalon. An ...
Other areas affected include the hippocampus, parahippocampal gyrus, and amygdala. Other than memory impairment, the ...
The entorhinal cortex is a portion of the rostral parahippocampal gyrus. It is usually divided into medial and lateral regions ... The superficial layers - layers II and III - of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to ... These layers receive input from other cortical areas, especially associational, perirhinal, and parahippocampal cortices, as ... dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum. ...
It consists of the cingulate gyrus, parahippocampal gyrus, amygdala, and the hippocampal formation. Studies in patients who ... which pass through the anterior cingulate gyrus. Cingulotomy was introduced in the 1940s as an alternative to standard pre- ...
Furthermore, the grey matter loss extends in to the cerebrum, parahippocampal gyrus and hippocampus. However, the gray matter ...
Along with the parahippocampal gyrus, the pyriform cortex is a chief component of paleocortex. The pyriform cortex is located ... is continuous with the parahippocampal cortex, and has extensive connections with the other parts of the cortex. Its strongest ...
... associated with lesions in the posterior part of the parahippocampal gyrus and anterior part of the lingual gyrus of the right ... Associative prosopagnosia is thought to be due to impaired functioning of the parahippocampal gyrus. Developmental ... It remains unclear whether the fusiform gyrus is specific for the recognition of human faces or if it is also involved in ... The functionality of the fusiform gyrus allows most people to recognize faces in more detail than they do similarly complex ...
The parahippocampal gyrus may reflect the formation of novel associations while solving insight problems. A fourth ERP study is ... in the parahippocampal gyrus (BA34). The data suggests that the parahippocampus is involved in searching for a correct answer ... In particular, increased activity was found in the right hemisphere anterior superior temporal gyrus. Some unconscious ...
This gyrus conceals the hippocampus. The parahippocampal gyrus is adjacent to the perirhinal cortex, which plays an important ... The hippocampus can only be seen in dissections as it is concealed by the parahippocampal gyrus. The cortex thins from six ... Sometimes the hippocampus is said to include the dentate gyrus and the subiculum. Some references include the dentate gyrus and ... including the dentate gyrus, several layers will be shown. The dentate gyrus has three layers of cells (or four if the hilus is ...
Four component areas have been described: parasubiculum (adjacent to the parahippocampal gyrus), presubiculum, postsubiculum, ...
... parahippocampal gyrus, amygdala, but relatively little expression in the insula. FAM193A has several specific chemical-gene ...
These areas are the posterior cingulate cortex, the parahippocampal gyrus, and the dorsal anterior cingulate cortex. ... show less activity in the left prefrontal cortex and the right dorsal superior frontal gyrus, which may indicate less ability ...
Eifuku, S. (2017). "Brodmann Areas 27, 28, 36 and 37: The Parahippocampal and the Fusiform Gyri". Brain and Nerve = Shinkei ... With its medial boundary corresponding approximately to the rhinal sulcus it is located primarily in the fusiform gyrus. ...
... it is situated between the parahippocampal gyrus and the anterior part of the fusiform gyrus. Coronal section through posterior ... Behind, it lies below and lateral to the calcarine fissure, from which it is separated by the lingual gyrus; in front, ...
Overall bilateral activation occurs in deception in the middle frontal gyrus, parahippocampal gyrus, the precuneus, and the ... The Parahippocampal cortex may be used in this process to generalize lies to situations because no cross-checking is needed. ... His studies showed that the inferior and superior prefrontal and anterior cingulate gyri and the parietal cortex showed ... posterior cingulate gyrus, prefrontal cortex, and cerebellum will be used to show a similar network for truth and lie. The most ...
The blood flow in the parahippocampal gyrus increased in conjunction with the individual's performance through the 3D maze. ... There are slow spindles in the range of 11 - 13 Hz that are associated with increased activity in the superior frontal gyrus, ... and the superior temporal gyri. They have different lengths. ...
... and joins the parahippocampal gyrus. This region is believed to play an important role in vision and dreaming. Visual memory ... The lingual gyrus, also known as the medial occipitotemporal gyrus, is a brain structure that is linked to processing vision, ... Lingual gyrus highlighted in green on sagittal T1 MRI images Lingual gyrus highlighted in green on coronal T1 MRI images ... Position of lingual gyrus (shown in red). Gyri and sulci of occipital and temporal lobe. Medial surface of cerebral hemisphere ...
Similarly there is also a region of the brain known as the parahippocampal place area on the parahippocampal gyrus. As the name ... and parahippocampal gyrus. The greater the activation in these areas during learning, the better the memory. Thus, these areas ... only the right prefrontal cortex and left parahippocampal gyrus are activated. These regions are associated with "a sense of ... Recognizing words, for example, involves the visual word form area, a region in the left fusiform gyrus, which is believed to ...
The entorhinal cortex is an infolding of the parahippocampal gyrus into the inferior (temporal) horn of the lateral ventricle. ... The EC projects to the dentate gyrus via the perforant pathway and by this means provides the critical input pathway in this ... From there, the information is then conveyed in series to the parahippocampal and perirhinal cortices, then onwards to the EC, ... From the EC, the information is sent back to the parahippocampal and perirhinal cortex, and finally back to the polymodal ...
Area 27 of Brodmann-1909 is a cytoarchitecturally defined cortical area that is a rostral part of the parahippocampal gyrus. It ...
The parahippocampal place area (PPA) is located in the posterior parahippocampal gyrus, which itself is contained in the medial ... the parahippocampal gyrus is involved in both spatial memory and spatial navigation (Squire & Zola-Morgan, 1991). The fusiform ... the parahippocampal place area (PPA) has been shown to have heightened activation when presented with buildings and place ... as patients who have experienced damage to the parahippocampal area demonstrate topographic disorientation, in other words, ...
... and anterior parahippocampal gyrus. More specifically, the human piriform cortex is located between the insula and the temporal ...
The parahippocampal gyrus (PHG), an area of grey matter surrounding the hippocampus, has been implicated in the amplification ... September 2009). "NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory ...
Parahippocampal gyrus shown in yellow. Close up of parahippocampal gyrus. Parahippocampal gyrus, shown in right cerebral ... Parahippocampal gyrus highlighted in green on coronal T1 MRI images Parahippocampal gyrus highlighted in green on sagittal T1 ... Parahippocampal gyrus shown red. Medial surface of left cerebral hemisphere. Parahippocampal gyrus shown in orange. Human brain ... Parahippocampal gyrus labelled as #5 Coronal section. Parahippocampal gyrus labelled at bottom center. Coronal section of ...
Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia ... Interstitial white matter neuron density in the dorsolateral prefrontal cortex and parahippocampal gyrus in schizophrenia ...
METHOD: The volumes of gray matter in the left and right parahippocampal and fusiform gyri were assessed with a stereological ... had lower volumes of both the parahippocampal and fusiform gyri on the left side. For both structures a left-greater-than-right ... but this asymmetry was reversed in the parahippocampal and fusiform gyri of the schizophrenic patients. A sex difference was ... adjacent to the parahippocampal gyrus on the ventral occipitotemporal surface. ...
... comprising an anterior portion of the left Superior and Middle Temporal Gyri (STG; MTG) that extended into the Parahippocampal ... Visser, M., Jefferies, E., Embleton, K. V., & Lambon Ralph, M. A. Both the middle temporal gyrus and the ventral anterior ... left grasps). Acronyms: ATC: Anterior Temporal Cortex; FG: Fusiform Gyrus; SPOC: Superior Parieto-Occipital Cortex. ... Gyrus (PHG). Other clusters surviving correction for multiple comparisons included those within the right Fusiform Gyrus (FG) ...
Hypoxic change in the right parahippocampal gyrus in a 19-year-old male who was an amateur boxer and received a blow to the ... Hypoxic change in the right parahippocampal gyrus in a 19-year-old male who was an amateur boxer and received a blow to the ... These contusions are frequently seen over the hippocampal, parahippocampal, and occipitotemporal gyri following GSWs to the ... Herniation may occur in the cingulate gyrus, the medial temporal gyrus or the uncus, the hypothalamic structures, and the ...
Parahippocampal Gyrus / physiology * Temporal Lobe / physiology * Time Perception / physiology* Grants and funding * MH060941/ ... distance revealed that the increasing recency of past events correlated with activity in the right parahippocampus gyrus ( ...
... patients presented with a seizure disorder related to a tumor in a PMT region involving the parahippocampal and fusiform gyri ... The SCTT approach uses a sitting position that offers a direct route to the posterior fusiform and lingual gyri of the temporal ... and lingual gyri, are challenging to perform because of the deep-seated location of these tumors between critical cisternal ... on those arising from the posterior parahippocampal, fusiform, ... Tumors arising from the parahippocampal and fusiform gyri of ...
... anterior cingulate gyrus, insular cortex, and Heschls gyrus; both thalami and precuneus; the left parahippocampal gyrus and ... Males had more grey matter volume in both amygdalae, hippocampi, anterior parahippocampal gyri, posterior cingulate gyri, ... The findings included females having more grey matter volume in the right frontal pole, inferior and middle frontal gyrus, pars ... Both males and females have consistent active working memory networks composed of both middle frontal gyri, the left cingulate ...
... parahippocampal gyrus and fusiform gyrus (Zuo et al. 2010).. These findings are suggestive of different mechanisms of ... TPJ, anterior insula, inferior frontal gyrus and, to a certain extent ventral mPFC show greater female co-activations; STG and ... with the first co-activating the bilateral middle frontal gyrus (MFG) and a portion of mPFC, and the latter showing higher ... while males show peaks in the cuneus and superior temporal gyrus (STG). The Emotion domain mostly involves the insula and mPFC ...
Axial gadolinium-enhanced T1-weighted image reveals enhancement of right anterior temporal lobe and parahippocampal gyrus. At ...
... parahippocampal gyrus. Fig. 10: Clockwise and counterclockwise path cell activity. Firing rate of a clockwise path cell from a ...
... parahippocampal gyrus; Ant, anterior medial temporal lobe). ...
... did not overlap strongly with anatomical sites identified as abnormal by structural MRI except in the parahippocampal gyrus, ... the inferior/superior temporal gyrus and the cerebellar vermis, regions where overlap was significant. Using the 22 genes in C1 ...
The orbitofrontal cortex, anterior cingulate cortex, hippocampus, parahippocampal gyrus, and amygdala, saw a rise in their ... parahippocampal gyrus and temporal pole), executive function (anterior cingulate cortex), and language processing ( ... the most consistent abnormalities were within the orbitofrontal cortex and the parahippocampal gyrus. ... included a greater reduction in gray-matter thickness and tissue contrast in the orbitofrontal cortex and parahippocampal gyrus ...
2. The anterior, hooked extremity of the parahippocampal gyrus on the basomedial surface of the temporal lobe; the anterior ... uncinate gyrus, u. gyri parahippocampalis. [L. a hook, fr. G. onkos] u. gyri parahippocampalis SYN: u. (2) . undecenoic acid ( ... 2. Relating to an uncus or, specifically, to the u. gyrus (2) or a process of the pancreas or of a vertebra. SYN: unciform. [L ...
When smelling the EO, participants showed the greatest activation in the amygdala and parahippocampal gyrus (a region ...
The parahippocampal gyrus links the default-mode cortical network with the medial temporal lobe memory system. Hum. Brain Mapp. ... Given that the parahippocampal cortex (PHC) mediates the connectivity of the hippocampus with major network hubs, including the ... 2016) do, that increased cross-talk between the angular gyrus, the insula and other brain networks plays a role in the ... KORs are expressed with high density in the striatum, hippocampal dentate gyrus, deep cortical layers V and VI (with more ...
... parahippocampal gyrus, brain stem, and cerebellum. ...
... including the amygdala and the parahippocampal gyrus. [29] ... superiorly by the dentate gyrus, and inferiorly by the ... MRI measurements of hippocampus, amygdala, cingulate gyrus, head of the caudate nucleus, temporal horn, lateral ventricles, ... Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimers disease. Neurology. 1991 ...
Grey matter correlates of flavour identification included entorhinal cortex, hippocampus, parahippocampal gyrus and temporal ... hippocampus and parahippocampal gyrus (peak MNI coordinates=−29, −18, −29; z-score=3.77) and temporal pole (peak MNI ... However, the hippocampus and parahippocampal region link incoming sensory stimuli with behavioural context,36-38 while the ... including the orbital surface of both frontal lobes and the lateral orbital gyri below the inferior frontal sulcus bilaterally ...
Journal Article] Selective impairment of race perception following bilateral damege in the fusiform and parahippocampal gyri. ...
This perception has been located by MRI in the right Parahippocampal gyrus; the part of the human brain that was originally ...
... rlingual gyrus = 0.401, p = 0.019, p(corr_fdr) = 0.0376), except for the parahippocampal gyrus (rparahippocampal gyrus = 0.257 ... C, Brain activation of the lingual gyrus and parahippocampal gyrus was significantly greater in the control condition compared ... B, During the pain stage, brain activation of the thalamus, insular, lingual gyrus, and parahippocampal gyrus was significantly ... The average PE values within ROIs (including the lingual gyrus and parahippocampal gyrus) were extracted from the four ...
... reduced left LC-parahippocampal gyrus connectivity was reported in aMCI patients (Jacobs et al., 2015). ... Another study found decreased connectivity between the left LC and the parahippocampal gyrus in mild cognitive impairment ( ... 2015) Relevance of parahippocampal-locus coeruleus connectivity to memory in early dementia Neurobiology of Aging 36:618-626. ...
Atrophy was seen in the hippocampus, thalamus, ventral striatum, parahippocampal gyrus, brain stem, and cerebellum. CRP levels ...
... parahippocampal gyrus, thalamus and medial prefrontal cortex during cue sound presentation. Together, these results suggest a ... In clear speech, alpha/beta power was more suppressed in the left inferior frontal gyrus and motor and visual cortices when ... When speech is degraded, posterior STS/middle temporal gyrus and medial temporal lobe are less engaged because integration load ... This study used magnetoencephalography to localize the theta consolidation effect to the left posterior middle temporal gyrus ( ...
Cannabis-Associated Psychotic-like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus. J Am Acad ...
The parahippocampal gyrus, the lateral orbitofrontal cortex, and the insula were particularly affected, and gray matter ...
... and parahippocampal gyrus (voxels of each cluster ,5, Fig. 4c). Considerable spatial variations became apparent (Table S11), ... middle temporal gyrus, middle frontal gyrus, and insula, while data processed with FSLVBM suggested that postcentral gyrus, ... superior frontal gyrus, superior temporal gyrus, and cerebellum strongly contributed to the prediction. Despite marked ... However, the overlap between all pipelines was only observed in the middle occipital gyrus (Fig. 4a and Table 2). Further ...
  • The parahippocampal gyrus (or hippocampal gyrus) is a grey matter cortical region of the brain that surrounds the hippocampus and is part of the limbic system. (wikipedia.org)
  • Contributions from the anterior cingulate, orbitofrontal, medial and lateral prefrontal cortices, and insular cortex connect with limbic structures within the temporal lobes such as the amygdala, hippocampus, and parahippocampal gyrus to integrate multiple brain processes needed to plan and organize goal-directed behavior, as well as attach emotional valence to memory. (psychiatrist.com)
  • hypothesized that memory function is associated with the pyramidal and granule cells located in the dentate gyrus of the hippocampus [ 6 ]. (hindawi.com)
  • We directly recorded the responses of individual neurons during flash suppression in the human amygdala, entorhinal cortex, hippocampus, and parahippocampal gyrus, allowing us to explore the neuronal responses in untrained subjects at a high spatial and temporal resolution in the medial temporal lobe. (harvard.edu)
  • When processing facial expressions of emotions, both patients with schizophrenia and healthy controls activated the bilateral amygdala and right fusiform gyri. (nih.gov)
  • When directly compared with controls, the extent of activation in bilateral amygdala, parahippocampal gyrus and fusiform gyrus, right superior frontal gyrus, and lentiform nucleus was significantly less in patients. (nih.gov)
  • The term parahippocampal cortex is used to refer to an area that encompasses both the posterior parahippocampal gyrus and the medial portion of the fusiform gyrus[citation needed]. (wikipedia.org)
  • An earlier report from our laboratory demonstrated that there were sex differences in the dendritic tree of granule neurons from the rat dentate gyrus (Juraska, Fitch, Henderson, & Rivers, 1985). (illinois.edu)
  • We found that urban upbringing and BDNF genotype interacted to alter activation in areas in the bilateral parahippocampal gyrus, whereby urban Met/Met carriers activated the least. (nih.gov)
  • Discussion: As was seen with the COMT gene, the BDNF-by-Urbanicity interaction yielded greatest activation in bilateral parahippocampal gyrus for carriers of the risk allele. (nih.gov)
  • Signal weakened regions could be found when needling at all the three points, the commonly activated regions were bilateral parahippocampal, hippocampal, callosal gyrus, bilateral praecuneus and cerebellum. (acupuncture.com)
  • 2. Anatomy and White Matter Connections of the Superior Frontal Gyrus. (nih.gov)
  • Our data show a robust reduction of cortical thickness in the left parahippocampal gyrus (PHG) in G allele homozygotes of GAD1 rs3749034. (nih.gov)
  • The findings appeared robust, replicating across paired frontal and temporal cortical samples from 113 ROSMAP brains, as well as in 151 parahippocampal gyrus tissues from the Mount Sinai Brain Bank and 40 DLPFC and anterior cingulate samples from the Emory Brain Bank. (alzforum.org)
  • Investigations of memory in rats and nonhuman primates have demonstrated functional specialization within the medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampal formation and underlying entorhinal, perirhinal, and parahippocampal cortices. (jneurosci.org)
  • The parahippocampal place area (PPA) is a sub-region of the parahippocampal cortex that lies medially in the inferior temporo-occipital cortex. (wikipedia.org)
  • RESULTS: The commonly activated regions were postcentral gyrus and right inferior frontal gyrus when needling at ST36 and SP6, and the different activated areas included left inferior frontal gyrus, left insula, left inferior parietal lobule, left culmen, left middle temporal gyrus and left middle frontal gyrus, while no cortical signal enhanced region was found when needling at GB34. (acupuncture.com)
  • The anterior part of the gyrus includes the perirhinal and entorhinal cortices[citation needed]. (wikipedia.org)
  • We found a COMT-by-urbanicity interaction whereby carriers of the risk allele, Val/Val showed more parahippocampal gyrus activation during an encoding task when raised exclusively in an urban environment. (nih.gov)
  • This produces brain activity markedly different from imaging playing tennis, with significant blood flow to the parahippocampal gyrus and other parts of the brain. (nationalrighttolifenews.org)
  • Parahippocampal place area (PPA) refers to an area in the temporal lobe that is activated by pictures of indoor and outdoor scenes. (psychology-lexicon.com)
  • For example, Rankin's research suggests that the right parahippocampal gyrus enables people to detect sarcasm. (wikipedia.org)
  • Individual difference analyses also found the magnitude of parahippocampal activation following gameplay onset to correlate with positive attitudes toward chemotherapy assessed both at the end of the scanning session and at an unannounced one-month follow-up. (ucla.edu)
  • 1. Anatomy and white matter connections of the orbitofrontal gyrus. (nih.gov)
  • 13. Anatomy and White Matter Connections of the Lingual Gyrus and Cuneus. (nih.gov)
  • Results Patients with AD (n = 206) had a median of 12 outlier regions (out of a possible 148), with the highest proportion of outliers (47%) in the parahippocampal gyrus. (asbah.org)
  • Onset of interactive game play robustly activated mesolimbic projection regions including the caudate nucleus and nucleus accumbens, as well as a subregion of the parahippocampal gyrus. (ucla.edu)
  • Results: Main effects of BDNF and urbanicity, as well as an interaction, were observed in the parahippocampal gyrus during encoding. (nih.gov)
  • These results suggest that pattern classification of Diffusion Tensor Imaging can help diagnosis of Alzheimer's disease, specially when focusing on the parahippocampal cingulum. (nature.com)
  • Additional research has suggested that the right parahippocampal gyrus in particular has functions beyond the contextualizing of visual background. (wikipedia.org)

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