Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)
Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.
Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.
Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in water, sewage, soil, meat, hospital environments, and on the skin and in the intestinal tract of man and animals as a commensal.

Synergistic protective effects of antioxidant and nitric oxide synthase inhibitor in transient focal ischemia. (1/220)

Both nitric oxide synthase (NOS) inhibitors and free radical scavengers have been shown to protect brain tissue in ischemia-reperfusion injury. Nitric oxide and superoxide anion act via distinct mechanisms and react together to form the highly deleterious peroxynitrite. Therefore the authors examined the effects and the interaction between the NOS inhibitor, NG nitro-L-arginine (LNA) and the antioxidant/superoxide scavenger, di-tert-butyl-hydroxybenzoic acid (DtBHB) in the rat submitted to 2 hours of middle cerebral artery occlusion. Posttreatment was initiated 4 hours after the onset of ischemia and infarct volume was measured at 48 hours. The dose-related effect of LNA resulted in a bell-shaped curve: 15, 56, 65, and 33% reduction of total infarct for 0.03, 0.1, 0.3, and 1 mg/kg (intravenously [IV]) respectively and 11% increase in infarct volume for 3 mg/kg (IV). Whereas DtBHB (20 mg/kg; intraperitoneally [IP]) was ineffective, the dose of 60 mg/kg produced 65% protection in infarct volume. The combination of a subthreshold dose of LNA (0.03 mg/kg; IV) and DtBHB (20 mg/kg; IP) resulted in significant reduction (49%) in infarct volume. These results show that LNA and DtBHB act synergistically to provide a consistent neuroprotection against ischemic injury when administered 4 hours after ischemia. This suggests that nitric oxide and free radicals are involved and interact in synergy in ischemia-reperfusion injury.  (+info)

Effect of neonatal exposure to estrogenic compounds on development of the excurrent ducts of the rat testis through puberty to adulthood. (2/220)

Neonatal exposure to diethylstilbestrol (DES) can alter the structure of the testicular excurrent ducts in rats. We characterized these changes according to dose and time posttreatment and established whether potent estrogens (ethinyl estradiol), environmental estrogens (genistein, octylphenol, bisphenol A, parabens), and tamoxifen induce such changes. Rats were administered these compounds neonatally and assessed at several time points during (day 10, or day 18 for some treatments) and after (days 18, 25, 35, and 75) the treatment period to detect any changes in testis weight, distension of the rete testis and efferent ducts, epithelial cell height in the efferent ducts, and immunoexpression of the water channel aquaporin-1 (AQP-1). Treatment with DES (10, 1, or 0.1 microg/injection; equivalent to 0.37, 0.037, or 0.0037 mg/kg/day, respectively) induced dose-dependent changes in testis weight and all parameters. These effects were most pronounced at days 18 and 25 and appeared to lessen with time, although some persisted into adulthood. Neonatal treatment with ethinyl estradiol (10 microg/injection; equivalent to 0.37 mg/kg/day) caused changes broadly similar to those induced by 10 mg DES. Administration of tamoxifen (2 mg/kg/day) caused changes at 18 days that were similar to those induced by 1 microg DES. Treatment with genistein (4 mg/kg/day), octylphenol (2 mg/injection; equivalent to 150 mg/kg/day), or bisphenol A (0.5 mg/injection; equivalent to 37 mg/kg/day) caused minor but significant (p<0.05) decreases in epithelial cell height of the efferent ducts at days 18 and/or 25. In animals that were followed through to 35 days and/or adulthood, these changes were no longer obvious; other parameters were either unaffected or were affected only marginally and transiently. Administration of parabens (2 mg/kg/day) had no detectable effect on any parameter at day 18. To establish whether these effects of estrogens were direct or indirect (i.e., resulting from reduced follicle-stimulating hormone/luteinizing hormone secretion), the above end points were assessed in animals in which gonadotropin secretion was suppressed neonatally by administration of a gonadotropin-releasing hormone antagonist. This treatment permanently reduced testis weight, but did not affect any of the other end points, apart from a minor transient reduction in efferent duct epithelial cell height at 18 days. This study suggests that structural and functional (expression of AQP-1) development of the excurrent ducts is susceptible to impairment by neonatal estrogen exposure, probably as a consequence of direct effects. The magnitude and duration of adverse changes induced by treatment with a range of estrogenic compounds was broadly comparable to their estrogenic potencies reported from in vitro assays.  (+info)

Cloning and sequencing of the fcbB gene encoding 4-chlorobenzoate-coenzyme A dehalogenase from Pseudomonas sp. DJ-12. (3/220)

Pseudomonas sp. DJ-12 degrades 4-chlorobenzoate through hydrolytic dechlorination to produce 4-hydroxybenzoate and a chloride ion. The fcbB gene encoding the 4-chlorobenzoate-coenzyme A (4CBA-CoA) dehalogenase which catalyzes the nucleophilic substitution reaction to convert 4CBA-CoA to 4-hydroxybenzoate-coenzyme A (4HBA-CoA) in the consecutive steps of dechlorination was cloned from the chromosome of the organism. A nucleotide sequence analysis of the gene showed an open reading frame consisting of 810 nucleotides, which can encode for a polypeptide of molecular mass 30 kDa, containing 269 amino acid residues. A promoter-like sequence (-35 and -10 region) and a putative ribosome-binding sequence were identified. A deduced amino acid sequence of the 4CBA-CoA dehalogenase showed 86%, 50%, and 50% identity with those of corresponding enzymes in the Pseudomonas sp. CBS3, Arthrobacter sp. SU, and Arthrobacter sp. TM1, respectively.  (+info)

Conserved cytoplasmic loops are important for both the transport and chemotaxis functions of PcaK, a protein from Pseudomonas putida with 12 membrane-spanning regions. (4/220)

Chemotaxis to the aromatic acid 4-hydroxybenzoate (4-HBA) by Pseudomonas putida is mediated by PcaK, a membrane-bound protein that also functions as a 4-HBA transporter. PcaK belongs to the major facilitator superfamily (MFS) of transport proteins, none of which have so far been implicated in chemotaxis. Work with two well-studied MFS transporters, LacY (the lactose permease) and TetA (a tetracycline efflux protein), has revealed two stretches of amino acids located between the second and third (2-3 loop) and the eighth and ninth (8-9 loop) transmembrane regions that are required for substrate transport. These sequences are conserved among most MFS transporters, including PcaK. To determine if PcaK has functional requirements similar to those of other MFS transport proteins and to analyze the relationship between the transport and chemotaxis functions of PcaK, we generated strains with mutations in amino acid residues located in the 2-3 and 8-9 loops of PcaK. The mutant proteins were analyzed in 4-HBA transport and chemotaxis assays. Cells expressing mutant PcaK proteins had a range of phenotypes. Some transported at wild-type levels, while others were partially or completely defective in 4-HBA transport. An aspartate residue in the 8-9 loop that has no counterpart in LacY and TetA, but is conserved among members of the aromatic acid/H(+) symporter family of the MFS, was found to be critical for 4-HBA transport. These results indicate that conserved amino acids in the 2-3 and 8-9 loops of PcaK are required for 4-HBA transport. Amino acid changes that decreased 4-HBA transport also caused a decrease in 4-HBA chemotaxis, but the effect on chemotaxis was sometimes slightly more severe. The requirement of PcaK for both 4-HBA transport and chemotaxis demonstrates that P. putida has a chemoreceptor that differs from the classical chemoreceptors described for Escherichia coli and Salmonella typhimurium.  (+info)

Effects of atovaquone and diospyrin-based drugs on ubiquinone biosynthesis in Pneumocystis carinii organisms. (5/220)

The naphthoquinone atovaquone is effective against Plasmodium and Pneumocystis carinii carinii. In Plasmodium, the primary mechanism of drug action is an irreversible binding to the mitochondrial cytochrome bc(1) complex as an analog of ubiquinone. Blockage of the electron transport chain ultimately inhibits de novo pyrimidine biosynthesis since dihydroorotate dehydrogenase, a key enzyme in pyrimidine biosynthesis, is unable to transfer electrons to ubiquinone. In the present study, the effect of atovaquone was examined on Pneumocystis carinii carinii coenzyme Q biosynthesis (rather than electron transport and respiration) by measuring its effect on the incorporation of radiolabeled p-hydroxybenzoate into ubiquinone in vitro. A triphasic dose-response was observed, with inhibition at 10 nM and then stimulation up to 0.2 microM, followed by inhibition at 1 microM. Since other naphthoquinone drugs may also act as analogs of ubiquinone, diospyrin and two of its derivatives were also tested for their effects on ubiquinone biosynthesis in P. carinii carinii. In contrast to atovaquone, these drugs did not inhibit the incorporation of p-hydroxybenzoate into P. carinii carinii ubiquinone.  (+info)

HbaR, a 4-hydroxybenzoate sensor and FNR-CRP superfamily member, regulates anaerobic 4-hydroxybenzoate degradation by Rhodopseudomonas palustris. (6/220)

Under anaerobic conditions, structurally diverse aromatic compounds are catabolized by bacteria to form benzoyl-coenzyme A (benzoyl-CoA), the starting compound for a central reductive pathway for aromatic ring degradation. The structural genes required for the conversion of 4-hydroxybenzoate (4-HBA) to benzoyl-CoA by Rhodopseudomonas palustris have been identified. Here we describe a regulatory gene, hbaR, that is part of the 4-HBA degradation gene cluster. An hbaR mutant that was constructed was unable to grow anaerobically on 4-HBA. However, the mutant retained the ability to grow aerobically on 4-HBA by an oxygen-requiring pathway distinct from the anaerobic route of 4-HBA degradation. The effect of the HbaR protein on expression of hbaA encoding 4-HBA-CoA ligase, the first enzyme for 4-HBA degradation, was investigated by using hbaA::'lacZ transcriptional fusions. HbaR was required for a 20-fold induction of beta-galactosidase activity that was observed with a chromosomal hbaA::'lacZ fusion when cells grown anaerobically on succinate were switched to anaerobic growth on succinate and 4-HBA. HbaR also activated expression from a plasmid-borne hbaA-'lacZ fusion when it was expressed in aerobically grown Pseudomonas aeruginosa cells, indicating that the activity of this regulator is not sensitive to oxygen. The deduced amino acid sequence of HbaR indicates that it is a member of the FNR-CRP superfamily of regulatory proteins. It is most closely related to transcriptional activators that are involved in regulating nitrate reduction. Previously, it has been shown that R. palustris has an FNR homologue, called AadR, that is also required for 4-HBA degradation. Our evidence indicates that AadR activates expression of hbaR in response to anaerobiosis and that HbaR, in turn, activates expression of 4-HBA degradation in response to 4-HBA as an effector molecule.  (+info)

Methyl p-hydroxybenzoate (E-218) a preservative for drugs and food is an activator of the ryanodine receptor Ca(2+) release channel. (7/220)

1. Haloperidol is a drug used in the management of several psychotic disorders and its use has been linked to Neuroleptic Malignant Syndrome. In the present study we have investigated the effect of a commercial preparation of haloperidol, Serenase, on skeletal muscle sarcoplasmic reticulum. 2. Addition of Serenase to isolated terminal cisternae caused a rapid release of calcium. We tested whether the active Ca(2+)-releasing substance was haloperidol or another compound present in the preparation. 3. Our results show that methyl p-hydroxybenzoate, one of the preservatives and a commonly used anti-microbial agent (E-218) is an activator of Ca(2+) release (E.C. 50=2.0 mM), mediated by a ruthenium red-sensitive Ca(2+) release channel present in skeletal muscle terminal cisternae.  (+info)

Antioxidative galloyl esters as enzyme inhibitors of p-hydroxybenzoate hydroxylase. (8/220)

Gallic acid and its esters were evaluated as enzyme inhibitors of recombinant p-hydroxybenzoate hydroxylase (PHBH), a NADPH-dependent flavin monooxygenase from Pseudomonas aeruginosa. n-Dodecyl gallate (DG) (IC(50)=16 microM) and (-)-epigallocatechin-3-O-gallate (EGCG) (IC(50)=16 microM), a major component of green tea polyphenols, showed the most potent inhibition, while product-like gallic acid did not inhibit the enzyme significantly (IC(50)>250 microM). Inhibition kinetics revealed that both DG and EGCG inhibited PHBH in a non-competitive manner (K(I)=18.1 and 14.0 microM, respectively). The enzyme inhibition was caused by specific binding of the antioxidative gallate to the enzyme, and by scavenging reactive oxygen species required for the monooxygenase reaction. Molecular modeling predicted that EGCG binds to the enzyme in the proximity of the FAD binding site via formation of three hydrogen bonds.  (+info)

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In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. The molar solubility of butyl paraben in pure solvents and its thermodynamic properties, measured by Differential Scanning Calorimetry, have been used to estimate the activity of the pure solid phase, and solution activity coefficients.. More than 5000 nucleation experiments of ethyl paraben, propyl paraben and butyl paraben in ethyl acetate, acetone, methanol, ethanol, propanol and 70%, 90% ethanol aqueous solution have been performed. The induction time of each paraben has been determined at three different supersaturation levels in various solvents. The wide variation in induction time reveals the stochastic nature of nucleation. The solid-liquid interfacial energy, free energy of nucleation, nuclei critical radius and pre-exponential factor of ...
Parabens are used to prevent the growth of microbes in cosmetics products and can be absorbed through skin, blood and the digestive system. Parabens have been found in biopsies from breast tumors at concentrations similar to those found in consumer products. Parabens may be found in a wide variety of products including facial cleansers, shampoos, lotions, deodorants, scrubs and eye makeup, and are found in nearly all urine samples from U.S. adults regardless of ethnic, socioeconomic or geographic backgrounds. Adolescents and adult females had higher levels of methylparaben and propylparaben in their urine than did males of similar ages.. Parabens are actually several distinct chemicals with a similar molecular structure. Four of these are used frequently in cosmetics: ethylparaben, butylparaben, methylparaben and propylparaben. Methylparaben and propylparaben are the most common of these. Parabens are most common in personal care products that contain significant amounts of water, such as ...
In fact, parabens themselves are natural substances found in food and so we are exposed to them through food. Parabens is the name given to a group of p-hydroxybenzoic acid (PHBA) esters. Parabens are biodegradable and natural. A growing number of manufacturers are now using Japanese honeysuckle extract in their products. This is a source of parabens and by using it the manufacturers are getting around the negative public perception of using parabens. We may have done parabens a big disservice and could find that they are actually the best and most natural preservative we can use. Lets keep an open mind on this. Here is more reading on the subject. ...
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I once read, in a comment somewhere related to beauty products, a girl gleefully explain that she loved parabens. I dont want no moldy lotion! ...Sad. Im sure youve heard some of the hype about parabens, and personally, yes, I know that they serve a purpose. But just like so many other chemicals, they are the cheapest way companies tend to deal with the problem, and they are harmful. Parabens act like estrogens in the body. Sure, we all have estrogen. But we shouldnt have extra. On top of everything else, not all estrogens are the same, and because these are alien estrogens, they dont behave the same way in our bodies. They are abundant in beauty and body products, which is really a shame. By the time a woman gets ready in the morning, she has exposed herself to hundreds of harmful chemicals already. High concentrations of estrogens have been found in breast cancer tumors, highlighting estrogens negative impacts on the disease. Parabens have been found to, in a way, feminize mens ...
Parabens are a group of compound used as preservatives in pharmaceutical and cosmetic industry. Parabens are widely used in beauty, skin care and fragrance ingredients to prevent bacteria and fungus growth. These are basically in almost every other product to increase shelf life. It has been estimated that women are daily exposed to 50 mg of paraben from cosmetic use. Continued use of products with parabens are known to be allergic and cause rashes. It easily penetrates in skin. Naturally parabens are found at low levels in certain foods whereas when applied to the skin and absorbed into the body, parabens in cosmetics bypass the metabolic process and enter the blood stream and body organs intact. Commonly found in make up, face and body cleanser, moisturizer and shampoos. Look for Methylparaben, Propylparaben, Isoparaben, Butylparaben on the label.. ...
Parabens are a class of chemicals used as an inexpensive preservative in cosmetics, food and pharmaceuticals. The use in personal care products is widespread and can be found in shampoos, laundry detergents and deodorants. Methylparaben, butylparaben, propylparaben and ethylparaben are commonly used paraben compounds that are found in tens of thousands products in America. Essentially, if you see any combination of words that contains paraben, you can be confident that you should be concerned about the potential negative effects of the product.. Manufacturers may be able to save some expense in the manufacture of their product at the costs to consumer health. Parabens also act as hormone disruptors and possess estrogenic activity. Researchers found that 14 of 17 parabens stimulate human estrogen receptors and that heptylparaben and pentylparaben exhibited the most potent estrogen (alpha and beta) agonist activity.. Nearly a decade ago, researchers found intact parabens accumulating in human ...
What is really surprising is that I went through all the other products I used trying to see if there were parabens in it (thereby proving whether or not parabens was causing the skin condition). The only American product that I used which had parabens in it was the Biore microscrub. I used it again today and noticed the slight skin irritation on my finger which went away in less than a minute (the effect was so brief I usually thought it was caused my the fact I like to wash my face in relatively hot water). So I suppose I am allergic, but it because the paraben was listed so low in the list (usually meaning there is less of it in the product) and that I only use the scrub 2-3 times a week I didnt have a severe enough reaction to know I was allergic. Whereas using the paraben cleanser on my face everyday, twice a day, just killed it ...
Parabens are one of the most widely used preservatives in personal care products, but many health concerns have cropped up over the years. So, should you be worried about slathering them on your skin? Its up for debate. While Marta has taken a stance against the use of parabens in skin care, her friend Nicki Benvenuti, founder and CEO of FutureDerm, sees less cause for concern. Here, they face off: Are parabens really a problem? Keep scrolling to read their discussion.
A few years ago in the world of personal care products, certain buzzwords started circulating in conversations, especially between mumz. Are you using paraben-free products? Did you hear what they are saying about sulfates? and the questions went on and on. All of a sudden, mumz were taking a good look at their own as well as their childrens personal care products, and it all became a little overwhelming and confusing!. Some products had parabens but were sulfate free and vice-versa, some had both, some had neither; which one to get?. Here is what you need to know without the long winded chemical names and the drama!. What are Parabens and are they evil?. Parabens are the most widely used chemical conservatives in cosmetics and personal care products, used to stop microbes like fungus and bacteria growing in your products. Over time, they have been linked to various forms of cancer in both men and women, but no studies to date have confirmed this - in fact, various health institutions ...
We assessed the estrogen agonist activities of 21 parabens and their chlorinated derivatives by using yeast two-hybrid assays incorporating either the human or medaka (Oryzias latipes) estrogen receptor alpha (hERalpha and medERalpha, respectively), and by using hERalpha competitive enzyme-linked immunosorbent assay (ER-ELISA). In the two-hybrid assay with hERalpha, five parabens and three chlorinated derivatives exhibited estrogenic activity, and their relative activity (17beta-estradiol [E2] = 1) ranged from 2.0 x 10(-5) to 2.0 x 10(-4), with the highest activity observed in i-butylparaben. In the medERalpha assay, six parabens and six chlorinated derivatives exhibited estrogenic activity and their relative activity ranged from 2.7 x 10(-5) to 3.5 x 10(-3), with the highest activity observed in benzylparaben, its monochlorinated derivative, i-butylparaben, and n-butylparaben. Although medERalpha demonstrated an activity to E2 that was three times lower than that demonstrated by hERalpha, medERalpha
Great podcast. I started making handmade cosmetics in 2012. I never read the labels on my cosmetics, bath, and beauty products. Now…I cannot buy anything without reading the label. I found that one of the best ways to keep preservatives away from my handmade products is to eliminate any water-based ingredients. I also use airless pumps to dispense my liquid products. I became obsessed with looking up every ingredient on EWGs website. Parabens may not be considered harmful but they do cause certain skin irritations for those with super sensitive skin. If youre using 3-4 everyday products loaded with parabens youre more likely to experience a reaction. My best advice is to stay away from parabens and products that have tons of synthetic ingredients. There are so many options for all-natural products online via Etsy and other Indie websites. I hardly ever buy cosmetics, bath, or beauty products at retail stores anymore.. ...
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Introduction Parabens are widely used as antimicrobial preservatives in medicines given to neonates. Some concerns have been raised about the potential of paraben toxicity. To date there have been no studies of the circulating concentrations of methyl paraben (MPB) in babies. This study aimed to describe the relationship between dose of MPB administered and circulating concentrations using a population pharmacokinetic model.. ...
An IQR increase in methyl paraben was associated with a 7.70% increase (95% CI 1.50, 13.90) in SHBG. Furthermore, an IQR increase in butyl paraben as associated with an 8.46% decrease (95% CI 16.92, 0.00) in estradiol, as well as a 9.34% decrease (95% CI −18.31,−0.38) in estradiol/progesterone. Conversely, an IQR increase in butyl paraben was associated with a 5.64% increase (95% CI 1.26, 10.02) in FT4. Progesterone was consistently negatively associated with phenols, but none reached statistical significance. After stratification, methyl and propyl paraben were suggestively negatively associated with estradiol at the first time point (16-20 weeks), and suggestively positively associated with estradiol at the second time point (24-28 weeks).. Conclusions ...
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Toxicokinetics Several studies have been identified that examine the basic toxicokinetics of Methylparaben: - Methylparaben was hydrolysed by both liver and skin microsomal/cytosolic fraction of humans and minipigs. The hydrolysis by human esterases was higher than that observed for minipigs. - High plasma levels and urinary output of free and conjugated p-Hydroxybenzoic acid (metabolite of Methylparaben) in dogs indicate that hydrolysis of the ester linkage and metabolic conjugate constitute the main paths of alteration for Methylparaben. Excretion via urine is almost complete 48 hours after application of 100 mg/kg bw to dogs. - 1 mg Methylparaben/kg bw/d was applied orally to a dog for one year. The rate of urinary excretion in the dog had increased to such an extent that after 24 hours 96% of the dose was recovered in the urine. - Methyl p-hydroxybenzoate sodium salt was administered to rabbits (800 mg/kg bw/d) and urine collected for 24 hours was examined for metabolites. After application ...
TUESDAY, Feb. 11, 2020 (HealthDay News) -- When pregnant women use cosmetics containing parabens, their children may have a greater likelihood of becoming overweight, a new study suggests.. Parabens are chemicals that have long been used as a preservative in cosmetics and body care products. A number of studies have suggested that parabens mimic estrogens in the body and may disrupt the normal function of hormones.. In the new study, researchers found detectable parabens in the urine of pregnant women who used paraben-containing leave-on products every day -- makeup, body lotion or facial moisturizers.. The higher those urinary paraben levels, the more likely it was that a womans child would be overweight by age 8.. A compound called butylparaben stood out: Kids were twice as likely to be overweight when their mothers prenatal levels of butylparaben were in the top one-third, compared to the bottom third. Girls, it seemed, were more affected than boys.. The findings do not prove that ...
Janice Carol Cosmetics offers a wide range of beauty products that are paraben free and are made from natural ingredients. The companys range of cosmetics includes skin cleansers, scrubs, blush, foundation, eyeliners, eye shadows, lip gloss, and lipstick.. What makes Janice Carol Cosmetics stand out from the crowd is that all their products are free from parabens; chemicals used by 85% of all other cosmetics companies to stop mold and microbes growing in products. However, parabens have been found to cause health issues in women. Parabens are xenoestrogens, which mimic female hormones and confuse the body into thinking its producing too much estrogen causing imbalances in the endocrine system.. The hormonal imbalances caused by Parabens then lead to health issues and disorders including infertility, thyroid problems, and even problems during pregnancy. More worryingly, Parabens have been found to be linked with breast cancer.. Against this backdrop, Janice Carol seized the opportunity to found ...
At the most recent Dallas Esthetic Show, I sought out my idol (and hopefully soon to be mentor), Dr. Pugliese. He is renown in the industry as a leader in skin care ingredient research and testing. Dr. Pugliese has also written one of my favorite books Physiology of the Skin. As a fellow scientist I appreciate his in depth knowledge and the continual research that he does.. During a classroom session, my new best friend, Dr. Pugliese (he may not be aware of this fact) and I were chatting about parabens, and all of a sudden this quiet, reserved man took on a whole different tone and voice. Dr. Pugliese, in no other words, explained that parabens are not harmful to the skin and that people are blindly blaming parabens without probable cause. I was absolutely astonished by this. As someone who eats organic, uses sulfate free products, and overall tries to be healthy, I have been under the impression for the past 5 years or so that parabens are bad. I had understood that parabens are wax ...
The pastry youre thinking about buying may contain the preservative propyl paraben, linked to disruptions in hormone signaling.
What should be the use of parabens and preservatives in cosmetic skincare? Why all the fuss about parabens? If you want to learn what this means for you, read this blog!
Q. Many commonly sold lubricants have parabens and other toxic ingredients in them-what sort of impact can inserting these types of ingredients into the body have on the female reproductive system?. A. Using lubricants with toxic ingredients has an effect on our reproductive system, as the vagina and anus are highly permeable areas and anything that is applied topically can be absorbed into the body. Parabens are a very common preservative in most cosmetics (moisturizers, face wash, lotions) that are used to prevent bacterial overgrowth. The problem is that parabens are endocrine disruptors, which means that they have an estrogenic effect in the body-they bind to the same cell receptors as our own estrogen but they interfere with our normal, rhythmic, hormonal process. Exposure to parabens has been associated with cancer and reproductive health issues and hormone imbalances like fibroids, endometriosis, infertility, and PMS.. Parabens have actually been found inside breast tumor cells. And while ...
0095] The composition may further comprise antimicrobial agents such as preservatives or antifungal agents chosen from alcohols, suitable for containing one or a plurality of aromatic substituents, for example phenoxyethanols such as 2-phenoxyethanol, 1-phenoxy-2-propanol, benzyl alcohol, 2-hydroxybiphenyl, parabens, such as methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, sodium methylparaben, sodium ethylparaben, sodium propylparaben, sodium isobutylparaben, sodium butylparaben or sodium isobutylparaben, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethylglycinate, halogenated derivatives such as iodopropynyl butylcarbamate, 2-bromo-2-nitropropan-1,3-diol, 2,4,4-trichloro-2-hydroxydiphenylether (triclosan), 3,4,4-trichlorocarbanilide (triclocarban), chlorbutanulum, 2,4-dichlorobenzyl alcohol, N-(4-chlorophenyl-N-(3,4-dichlorophenyl urea, 1,2-dibromo-2,4-dicyanobutane, chloroxylenol, ketoconazole, oxiconazole, butoconazole, clotrimazole, econazole, ...
How to know if your skin care products contain parabens and what to do. You may have heard of these sneaky little preservatives called parabens. They
BACKGROUND: Biobank serum samples from longitudinal mother-child cohorts have been used to estimate prenatal exposures to endocrine disrupting chemicals (EDCs). However, the knowledge about variations in serum concentrations of non-persistent chemicals during pregnancy is limited.. OBJECTIVE: To describe the within- and between-person variations in serum concentrations of non-persistent chemicals and changes over trimesters, including phthalate metabolites, parabens, phenols, and UV filters.. DESIGN: Longitudinal study with repeated blood samples from 128 healthy pregnant women during pregnancy.. SETTING: Population based study at a University Hospital in Copenhagen 1999-2001.. METHODS: 503 repetitive prenatal serum samples from 128 pregnant women taken at approximately gestational week 12, 20, 30 and 40 were analyzed for 7 UV filters, 32 metabolites of 15 phthalate diesters, 8 phenols and 7 parabens by LC-MS/MS.. RESULTS: Ten of 32 phthalate metabolites from six out of 15 phthalate diesters, ...
Recent research has made us realise just how important it is to read all labels - and not just on the foods we are buying. A new study has now shown how parabens (found in numerous drugs, foods, personal care products and cosmetics) are detected in different parts of our bodies and which areas are the most sensitive to these parabens.
Through lotions, shampoos and other personal care products (PCPs), infants and toddlers are likely becoming exposed to potentially harmful substances, called parabens, at an even higher level than adult women in the U.S., researchers have reported. They published their findings on parabens, which have been linked to reproductive and other health issues, in the ACS…
The bottom line is that all we can do is educate ourselves on the ingredients were are putting into our bodies. How many of us ignore those long lists of unpronounceable ingredients on our products, blissfully washing or eating whatever it may be, without having any idea what that ingredient even does or where it comes from? The lesson is this: education is key, especially when it comes to how we take care of our selves. Hopefully you have learned something new about Parabens from this article and can come to an opinion about them that you are comfortable with. No matter what your personal opinion, the world of skin care is vast, and we have something for everyone here at Sanctuary Spa. Whether you feel safe using products with Parabens, or if you are the all-organic type, we can help you find a skin care regimen that meets your needs and goals! For those of you on the Prosecuting side, ask about our organic skin care line and facial by Eminence Organics! Safe, natural, with no harmful chemicals ...
Bye Bye Parabens is a hair care product line for naturally curly hair. Shampoo, Conditioners, Styling Aids, and Treatments all made for naturally curly hair. Dont worry, all of the products are PARABENS FREE.. Email: [email protected] ...
Over the years, parabens have gained a bit of a bad rep. Studies say one thing, newspapers say another. So, whats the real truth about parabens in our beauty products? Kate Shapland explains it all...
Pret Subrina Professional PHI Colour sampon dupa vopsire (0% Parabens, Formaldehyde Releasers) 1000 ml Original. Cumpara acum Subrina Professional PHI Colour sampon dupa vopsire (0% Parabens, Formaldehyde Releasers) 1000 ml la pretul de 49 lei. Produsele din gama Subrina Professional PHI sunt Originale si se afla pe stoc. Cod produs SUBPHCW_KSHA30. Plasati o comanda online de peste 100 lei si primiti un cadou gratuit. Cosmetice si Parfumuri Subrina Professional PHI Originale si Ieftine. Produse Subrina Professional PHI pentru femei si barbati la cel mai bun pret.. ...
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Creative-Proteomics offer cas 99-76-3 METHYL PARABEN (METHYL 4-HYDROXYBENZOATE) (RING-13C6, 99%) 1 MG/ML IN METHANOL. We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
Product Description• A combination of placenta and herbal extracts• Reduces wrinkle and helps heal scars• Suitable as a day creamDescriptionPlacenta Herbal Complex™ is a sophisticated cream designed to moisturise, revive and protect the skin from harsh environment. It contains placenta extract, aloe vera and jojoba extracts to soothe and heal the skin whilst vitamin E ensures deep hydration. It is also excellent as a day cream as it contains added sunscreen.Ingredients / Active IngredientsIngredients: Water Purified, Caprylic/Capric Triglyceride, Stearic Acid, Glycerin, Cyclomethicones, Stearyl Alcohol, Ceteareth-20, Propylene Glycol, Phenyl Trimethicone, Cetyl Alcohol, Octyl Methoxycinnamate, Jojoba Oil, Dimethicone, Alpha Tocopheryl Acetate, Phenoxyethanol, Methyl Paraben, Propyl Paraben, Ethyl Paraben, Butyl Paraben, Aloe Vera Extract, Triethanolamine, Carbomer, Xanthan Gum, Butylated Hydroxytoluene, Sheep Placental Extract, Liposomes.DirectionsGently smooth on face and neck twice daily.
The results of an inter/intra-laboratory study into a test and reference reaction for isothermal microcalorimeters, the imidazole catalysed hydrolysis of triacetin, have been reported in a recent paper [Thermochim. Acta 380 (2001) 13]. The results and conclusions drawn from this study have been extended to a consideration of the need for a similar test and reference reaction for isothermal microcalorimeters operating in flow mode. This paper reports the findings of a preliminary inter/intra-laboratory study of the base catalysed hydrolysis of methyl 4-hydroxy benzoate (methyl paraben) and its suitability as a test and reference reaction. The derived values for the hydrolysis reaction were (3.15 +/- 0.11) x 10(-4) s(-1) and -50.5 +/- 4.3 kJ mol(-1) for the rate constant and enthalpy, respectively. It is also reported how such a test and reference reaction can be used to validate the thermal output from a LKB 10-700-1 and Thermometric Thermal Activity Monitor (TAM) 2277-202 flow ...
These preservatives are contained in almost all creams. Yes, this makeup will give you the desired effect, but will have to pay for your beauty. Parabens are most often associated with the risk of developing breast cancer. At high concentrations and the interaction with UVB rays the negative impact will be much higher. Although some scholars argue that in the makeup parabens not so much that they can not in any way affect human health. To learn about them, composed by the legend: Butylparaben, Propylparaben, Ethylparaben, methylparaben is.. ...
Instructions for use: Squeeze a pea-size amount onto your toothbrush Add water, brush and rinse 75ml/3.8 fl.oz. Ingredients: Aquatic Mint: Aluminum Hydroxide, Aqua (Water), Sorbitol, Glycerin, Silica, Aroma (Flavor), Cellulose Gum, Sodium Laureth Sulfate, Titanium Dioxide, Sodium Lauryl Sulfate, Citric Acid, Sodium Flouride, Sodium Saccharin, Phenoxyethanol, Imidazolidinyl Urea, Methylparaben, Propylparaben, Ethylparaben, Butylparaben, Hydroxycitronellal, Farnesol Classic Strong Mint: Aluminum Hydroxide, Aqua (Water), Sorbitol, Glycerin, Silica, Aroma (Flavor), Cellulose Gum, Sodium Laureth Sulfate, Titanium Dioxide, Sodium Lauryl Sulfate, Citric Acid, Sodium Fluoride, Sodium Saccharin, Phenoxyethanol, Imidazolidinyl Urea, Methylparaben, Propylparaben, Ethylparaben, Butylparaben, Eugenol, Limonene Whitening Mint: Glycerin, Hydrated Silica, Aqua (Water), Tetrapotassium Pyrophosphate, PEG-32, Sodium Lauryl Sulfate, Aroma (Flavor), Cellulose Gum, Xylitol, Titanium Dioxide, Sodium
Ethylparaben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Its formula is HO-C6H4-CO-O-CH2CH3. It is a member of the class of compounds known as parabens. ...
Parabens are preservative ingredients found in many cosmetic and hair products, but what do they actually do to your skin and hair?
Parabens are the most commonly used preservatives in cosmetic, pharmaceutical, and industrial products. But what is the paraben paradox?
Parabens are chemicals contained in everyday personal care products. They can cause cellular damage, allergies and disrupt the endocrine system. Learn why theyre toxic and how to avoid them.
Studies have shown that parabens are endocrine disruptors, they interfere with our natural hormones, and theyve been found in breast cancer tumors.
TY - JOUR. T1 - Prenatal phenol and paraben exposures in relation to child neurodevelopment including autism spectrum disorders in the MARBLES study. AU - Barkoski, Jacqueline M.. AU - Busgang, Stefanie A.. AU - Bixby, Moira. AU - Bennett, Deborah. AU - Schmidt, Rebecca J.. AU - Barr, Dana Boyd. AU - Panuwet, Parinya. AU - Gennings, Chris. AU - Hertz-Picciotto, Irva. PY - 2019/12. Y1 - 2019/12. N2 - Background: Environmental phenols and parabens are endocrine disrupting chemicals (EDCs) with the potential to affect child neurodevelopment including autism spectrum disorders (ASD). Our aim was to assess whether exposure to environmental phenols and parabens during pregnancy was associated with an increased risk of clinical ASD or other nontypical development (non-TD). Methods: This study included mother-child pairs (N = 207) from the Markers of Autism Risks in Babies - Learning Early Signs (MARBLES) Cohort Study with urinary phenol and paraben metabolites analyzed using liquid ...
Climax Bursts Lubricants are glycerin-free, enriched with vitamin E and water based. The climax beads burst on contact for erotic sensations. The problem is that the contain Parabens. These have been found to cause health problems and is why we will not carry their products until they change this. We do carry paraben free, glycerin lubricants.
... , also methyl paraben, one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO). It is ... "Parabens". Food and Drug Administration. 9 September 2020. Soni MG, Taylor SL, Greenberg NA, Burdock GA (October 2002). " ... Okamoto Y, Hayashi T, Matsunami S, Ueda K, Kojima N (August 2008). "Combined activation of methyl paraben by light irradiation ... "Bloomington Drosophila Stock Center". Gu W, Xie DJ, Hour XW (2009). "Toxicity and Estrogen Effects of Methyl Paraben on ...
Fransway, AF; Fransway, PJ; Belsito, DV (2019). "Parabens". Dermatitis. 30 (1): 3-31. doi:10.1097/DER.0000000000000429. PMID ... Parabens (Non) Allergen 2018 - Propylene Glycol 2017 - Alkyl Glucoside 2016 - Cobalt 2015 - Formaldehyde 2014 - Benzophenones ...
Long-chained parabens, like butylparaben, are more estrogenic than short-chained parabens, like methyl- or ethylparaben. This ... In most cosmetics paraben is used at low levels, ranging from 0.01 to 0.3%. Butylparaben is used in low concentrations in ... However, parabens have not been proven to cause breast cancer. Estimates by the U.S. Food and Drug Administration and the ... Members of the paraben family are found in fruit and vegetable products, such as barley, flax seed, and grapes. Butylparaben ...
"Parabens Evelina Coelho". Retrieved 31 December 2015. Jornal A Guarda. "Centro Escolar do Vale do Mondego". ...
Parabens can cause skin irritation and contact dermatitis in individuals with paraben allergies, a small percentage of the ... Byford JR, Shaw LE, Drew MG, Pope GS, Sauer MJ, Darbre PD (January 2002). "Oestrogenic activity of parabens in MCF7 human ... Animal experiments have shown that parabens have a weak estrogenic activity, acting as xenoestrogens. Perfumes are widely used ... Nagel JE, Fuscaldo JT, Fireman P (April 1977). "Paraben allergy". JAMA. 237 (15): 1594-5. doi:10.1001/jama.237.15.1594. PMID ...
Furthermore, some of them contain parabens. Parabens are preservatives that can affect the endocrine system. Indoor tanning ... Harvey, Philip W.; Everett, David J. (2004). "Significance of the detection of esters of p-hydroxybenzoic acid (parabens) in ...
Miguel Valle Ávila, "Parabens Nossa Tribuna." The Portuguese Tribune. 30th Anniversary Edition. September 1, 2009. Fernando ...
"CASDT Hatoo Parabens PR Eleitu Lu-olo". STLNEWS. 2017-03-29. Retrieved 2021-08-19. Xavier, Jacinto. "ParPol 5 Deklara Apoiu Lu- ...
Darbre PD, Aljarrah A, Miller WR, Coldham NG, Sauer MJ, Pope GS (2004). "Concentrations of parabens in human breast tumours". J ... parabens (lotions) phthalates (plasticizers) DEHP (plasticizer for PVC) Propyl gallate (used to protect oils and fats in ...
... is a paraben. Isopropylparaben has been prepared via the stepwise addition of isopropanol, thionyl chloride, ...
Its net weight is usually 4 grams (0.14 oz). When manufactured by Wyeth, Chapstick contained no parabens. ChapStick functions ...
Nguyen, T.; Clare, B.; Martinac, B.; Martinac, Boris (2005). "The effects of parabens on the mechanosensitive channels". Eur. ...
It is a member of the class of parabens. It is a preservative typically found in many water-based cosmetics, such as creams, ... Oishi (2002). "Effects of propyl paraben on the male reproductive system". Food and Chemical Toxicology. 40 (12): 1807-13. doi: ... Directorate-General for Consumer Safety, European Union (2011). "Scientific Committee on Consumer Safety Opinion on Parabens ...
... does not use parabens, mineral oil, synthetic fragrances or gluten in their products. Parabens are excluded ... "Should People Be Concerned about Parabens in Beauty Products?". Scientific American. Retrieved 2018-12-13. "3 Key Reasons to ...
"Amended Safety Assessment of Parabens as Used in Cosmetics". International Journal of Toxicology. 39 (1_suppl): 5S-97S. doi: ...
The company's cosmetics are not tested on animals; are paraben-free and phthalate-free; and most are vitamin-infused, vegan, ...
P. gergoviae is of special interest to the cosmetics industry, as it displays resistance to parabens, a common antimicrobial ... "Enterobacter gergoviae and the prevalence of efflux in parabens resistance". Journal of Antimicrobial Chemotherapy. 57 (4): 757 ...
Parabens are used to preserve a number of the products. Lush focuses on limited packaging for its product range, or package- ...
All products are sulfate and paraben free.[citation needed] Verrilli began his career in the beauty industry in Sudbury, ...
Some manufacturers are using this preservative as a replacement for parabens. Tube feeding of potassium sorbate reduces the ...
Hormone disruption resulting from the inclusion of parabens as a preservative. Eye irritations should the product accidentally ...
"Brasil zera imposto de importação para bens de informática e de telecomunicações". 21 May 2020. Retrieved 4 July ...
September 2017). "Prenatal exposure to bisphenols and parabens and impacts on human physiology" (PDF). Physiological Research. ...
It is a member of the class of compounds known as parabens. It is used as an antifungal preservative. As a food additive, it ... Ethyl paraben, v t e (Articles with short description, Short description matches Wikidata, ECHA ... Parabens, All stub articles, Aromatic compound stubs). ...
Parabens are also an estrogen mimicker and are chemically the same structure. Phthalates: Phthalates are used in cosmetics as " ... For example, EDCs such as parabens, phthalates, and triclosans can be found in everyday household items such as generic ... "Urinary Excretion of Phthalates and Paraben after Repeatedwhole-body Topical Application in Humans." International Journal of ... Parabens: inhibit the growth of yeasts, molds, and bacteria in cosmetic products and can be found in deodorants, facial scrubs ...
... (heptyl p-hydroxybenzoate) is a compound with formula C7H15(C6H4OHCOO). It is a paraben which is the heptyl ester ... Parabens". Applied and Environmental Microbiology. 72 (8): 5556. doi:10.1128/AEM.00494-06. PMC 1538717. PMID 16885309. v t e ( ...
Bactericidal products such as triclosan (TCS) and parabens kill bacteria on the skin. Alcohols and related compounds such as ... According to the American Cancer Society, "studies have not shown any direct link between parabens and any health problems, ... Another constituent of deodorant products that has given cause for concern are parabens, a chemical additive. ...
The brand is cruelty-free, paraben-free and 100% vegan. Styled as clean, cool beauty the brand has won multiple awards ...
... preparations may contain methylparaben and propylparaben and are inappropriate for use by people with a paraben ... Preservative-free preparations are available for those with paraben hypersensitivities. Naloxone is a lipophilic compound that ...
Preservatives like parabens and benzoates and antioxidants like butylated hydroxytoluene (BHT) and sodium metabisulfite. ...
Often more than one paraben is used in a single product.. How People Are Exposed to Parabens. People can be exposed to parabens ... Parabens also can enter the body when pharmaceuticals, foods, and drinks containing parabens are swallowed or eaten. Parabens ... Levels of Parabens in the U.S. Population. Centers for Disease Control and Prevention scientists measured parabens in the urine ... How Parabens Affect Peoples Health. Human health effects from environmental exposure to low levels of parabens are unknown. In ...
Joint FAO/WHO Expert Committee on Food Additives. Meeting (‎67th : 2006 : Geneva, Switzerland)‎; International Programme on Chemical Safety (‎World Health OrganizationWorld Health Organization, 2008)‎ ...
Paraben Free Gifts by Rebel Girls Our gift guides ensure youll find the perfect conscious gift for any occasion. Stylish, ... You are viewing Paraben Free products from Rebel Girls in our Gifts category ...
URXBUP - Butyl paraben (ng/ml). Variable Name: URXBUP. SAS Label: Butyl paraben (ng/ml). English Text: Butyl paraben (ng/ml). ... URXEPB - Ethyl paraben (ng/ml). Variable Name: URXEPB. SAS Label: Ethyl paraben (ng/ml). English Text: Ethyl paraben (ng/ml). ... URXMPB - Methyl paraben (ng/ml). Variable Name: URXMPB. SAS Label: Methyl paraben (ng/ml). English Text: Methyl paraben (ng/ml) ... URXPPB - Propyl paraben (ng/ml). Variable Name: URXPPB. SAS Label: Propyl paraben (ng/ml). English Text: Propyl paraben (ng/ml) ...
Joint FAO/WHO Expert Committee on Food Additives. Meeting (‎67th : 2006 : Geneva, Switzerland)‎; International Programme on Chemical Safety (‎World Health OrganizationWorld Health Organization, 2008)‎ ...
Parabens (p-hydroxybenzoic acid esters), bisphenols, benzophenone-type UV filters, triclosan, and triclocarban are used in a ... The total amount of the sum of six parent parabens (Σ6 Parabens) leached from teethers ranged from 2.0 to 1990 ng, whereas that ... Parabens (p-hydroxybenzoic acid esters), bisphenols, benzophenone-type UV filters, triclosan, and triclocarban are used in a ... Migration of parabens, bisphenols, benzophenone-type UV filters, triclosan, and triclocarban from teethers and its implications ...
The Cosmetic Ingredient Review has re-evaluated parabens and have deemed them safe once again. ... Parabens may have nothing wrong with them after all. The preservatives used in cosmetics and personal care products have been ... According to WWD, in meetings over the past few days the Cosmetic Ingredient Review has re-evaluated parabens and have deemed ... The concern seems to be stemmed from the way parabens act as estrogen. And while estrogenic activity in the body is associated ...
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7 Abstracts with Parabens-Associated Toxicity Research. Filter by Study Type. Animal Study. ... Ginger extract ameliorates paraben induced biochemical changes in liver and kidney of mice.May 01, 2007. ... Ginger significantly reduces paraben induced lipid peroxidation in liver and kidney cells. Jan 01, 2007. ... Neonates might be exposed to multiple sources of BPA and parabens in neonatal intensive care units.Oct 31, 2019. ...
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Parabens, esters of p-hydroxybenzoic acid, are used as preservatives in cosmetics and foods. Common parabens include ... This chromatogram indicates that each paraben elutes with good separation within a minute. As shown above, a UHPLC column (X- ... Figure 1. Chromatogram of a standard mixture of parabens and p-hydroxybenzoic acid. Peaks: 1=p-hydroxybenzoic acid, 2= ... Figure 1 shows the chromatogram of a standard mixture of parabens and p-hydroxybenzoic acid. ...
Visit HowStuffWorks to learn all about paraben-free lotion. ... Paraben-free lotion is necessary for some people. ... What is a Paraben? Parabens are antifungal agents that are used as preservatives in foods, pharmaceuticals and skin care ... Paraben-free products can be a bit more expensive, but they may put your mind at ease. To learn more about parabens, ... Using Paraben-free Lotion Paraben-free lotions are no different from other lotions -- they just contain different preservatives ...
Contact us using our enquiry form or feel free to call or email using the Phone Number and Email displayed. Our preferred communication method is email but if you need to speak to us you can call us anytime between: 9.00-17.00 MST, Monday to Friday. ...
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Access to Paraben Support. Paraben has a team of support personnel with many years of experience and you can access them ... Paraben also accepts payment via PayPal and you can work with our Customer Service department to arrange that option. You can ... Just email us at [email protected] and explain the issue. We want to support you so we will do our best to offer an ... Parabens Student Program was designed to support you through your educational process. We offer you a license to the E3 ...
The removal of parabens by some cosmetic manufacturers is a reaction to ... FDA dedicates section of website to paraben safety * Paraben-free claims continue to charm consumers; beauty industry profiting ... The removal of parabens by some cosmetic manufacturers is a reaction to "outrageous claims" made by the media and pressure from ... Parabens bad press based on flawed science, says industry insider. By Katie Bird ...
Home » Reviews » Paraben Forensic Innovation Conference (PFIC). Paraben Forensic Innovation Conference (PFIC). 27th May 2020. ... Paraben claims that once you start cloning, it intercepts writes to the disk and stores those in a RAM disk until such time ... Kudos to Paraben.. Their lab machines consisted of mostly Macs. They were donated, I believe, by BlackBag. They were dual boot ... Paraben claims that it is undetectable (although someone with their support staff claimed he could find it). You can view the ...
... conditioners without parabens. Here, we discuss the dangers of parabens in shampoo.​ ... Are parabens in your shampoo? Experts suggest its best to use shampoos & ... Are all parabens bad?. When I mentioned parabens in a previous article, I received some angry messages insisting that parabens ... Exposure to Parabens Over Time Is a Concern. For me, the threat of danger from exposure to parabens is not a one-time use and ...
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eShave Paraben Free Travel Size Shaving Cream Verbena Lime generates a rich lather for a close and comfortable shave free of ... eShave Travel Size Shaving Cream Verbena Lime is Paraben Free, Sulfate Free and Vegan. It contains NO SLS, NO SLES and NO ... Clean products: Free of Paraben, Sulfate, SLS, SLES, colors or animal ingredients.. Unique Scents and superior quality ...
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  • Exposure to phenols, phthalates, and parabens and development of metabolic syndrome among Mexican women in midlife. (
  • This Bar Soap Cleanser Is Formulated with No Parabens, No Phthalates, No Mineral Oil and No Sulfates. (
  • You know I'm not an extremist in any way, but if I can avoid parabens, phthalates and sulfates I'm going to. (
  • They also may have "clean" formulas that don't contain chemicals potentially harmful to the body, such as sulfates, parabens, and phthalates. (
  • What are Parabens and Sulfates? (
  • When it comes to parabens and sulfates, the truth likely lies somewhere in the middle. (
  • The fact remains that despite scientific evidence that they may cause health problems, parabens and sulfates are both widely used in beauty products today. (
  • To understand this, we will be defining parabens and sulfates, getting to the bottom of health concerns, review some natural alternatives to these ingredients, and go over some frequently asked questions. (
  • Due to the connection between sulfates and parabens, many of the health concerns have been interchanged. (
  • As we have established, parabens are primarily used as preservatives and sulfates are primarily used to strip away unwanted oils and increase skin permeability. (
  • This begs the question: are there natural alternatives to parabens and sulfates? (
  • Are products required to label parabens and sulfates? (
  • However, there is no requirement to specifically state whether or not a product contains parabens and/or sulfates. (
  • Unfortunately, many parabens and sulfates have long, complex names which are not always obvious to spot such as propylparaben, isobutylparaben, sodium lauryl sulfate, etc. (
  • It is hand-crafted with only the finest quality organic oils and is free of parabens, sulfates and gluten. (
  • The cosmetic industry formally requested that CIR re-examine the safety of parabens as they are used in cosmetics, and we are gratified that the panel has done so and confirmed the safety of these ingredients," said Halyna Breslawec, chief scientist for the PCPC to WWD . (
  • Unusual Skin Care Ingredients Image Gallery While some lotions are paraben-free, they still contain other preservatives. (
  • The U.S. Food and Drug Administration requires that all ingredients in skin care products be listed on the label, so read product labels carefully to be sure they don't contain parabens [source U.S. Food and Drug Administration ]. (
  • Although the industry regulatory bodies maintain that the levels at which the parabens are used are safe, some argue the ingredients pose health dangers. (
  • Anything that didn't have parabens in it stayed and if they have ingredients I don't love I will replace it when I'm done. (
  • Due to consumer concerns about the the safety of these compounds, parabens have been replaced with other ingredients that have far greater potential for allergies. (
  • We've always used types of parabens that have been proven safe - Dove products take care of your skin and don't use harmful skincare ingredients. (
  • Cuticle Lissé paraben- and sulfate-free shampoos are gentle and safe for your hair extensions, and contain ingredients that will infuse a new life into them. (
  • tell your doctor and pharmacist if you are allergic to becaplermin, parabens, any other medications, or any of the ingredients in becaplermin gel. (
  • No SLS, parabens, silicones or mineral oils. (
  • It is also free of all harmful parabens, sulphates, silicones and salts. (
  • Those that offer the best protection for curls are made without parabens, silicones, alcohol or sulphates. (
  • There are several types of parabens, the most common being methylparaben, probylparaben and butylparaben [source U.S. Food and Drug Administration ]. (
  • Although parabens have estrogen-like effects, butylparaben - the most potent paraben - is 10,000 to 100,000 times weaker than estrogen and not thought to be capable of causing negative health effects. (
  • The effect of one of the longer paraben molecules being butylparaben suggests that it should be the most harmful. (
  • CDC scientists found Methylparaben and propylparaben in the urine of most of the people tested, indicating widespread exposure to these parabens in the U.S. population. (
  • Females had several-fold higher concentrations of methylparaben and propylparabens than males, which likely reflect the greater use of products containing parabens. (
  • In fact, an analysis of the urine of 100 adults found that 99 of them had methylparaben - the most commonly used paraben - in their urine. (
  • Experts have been telling us to use hair conditioners and shampoo without parabens or sulfate for quite some time now. (
  • This hair shampoo without sulphates, parabens and dyes has been specially formulated to care at hair's cellular level.pply to wet hair, lather and rinse. (
  • Purchase paraben- and sulfate-free hair extension shampoo from Cuticle Lissé to maximize the life of your hair extensions by keeping them healthy and beautiful for as long as possible. (
  • This paraben- and sulfate-free shampoo penetrates and repairs the cuticle - hydrating, softening, and strengthening your hair and extensions from the inside out and maximizing the life of your hair extensions. (
  • This paraben- and sulfate-free shampoo contains keratin that has been isolated from New Zealand Wool - great for taming frizz, adding shine, and making curly hair more manageable. (
  • For the best possible care of your hair extensions, you should only consider Paraben and Sulfate Free shampoo for hair extensions from Cuticle Lissé. (
  • This shampoo is free of parabens (which can disrupt the reproductive system), sodium lauryl (an irritant and pollutant), phthalate (a possible carcinogen and hormone disrupter), and butylene glycol (a preservative). (
  • But once you understand parabens, the reality of the cancer risk and the availability of paraben-free products, you'll be better equipped to make product decisions. (
  • In our research for the best Paraben-Free Bath Soaps we have checked 792 reviews through our system and have selected the top 20 to display on our website. (
  • Sensual, long-lasting, and hypoallergenic, BioGenesis is the first fertility-friendly intimacy gel that's both paraben-free and includes magnesium and calcium ions to support your fertility journey. (
  • Every aspect of our formula - paraben-free, water-based, with hydroxyethylcellulose, plus calcium and magnesium ions - was designed to support your journey to pregnancy. (
  • eShave Travel Size Shaving Cream Verbena Lime is Paraben Free, Sulfate Free and Vegan. (
  • Vichy Pureté Thermale Hydrating Foaming Cream Facial Cleanser, Paraben-free, Alcohol-free, 4.2 Fl. (
  • Paraben and preservative free, this outstanding anti-aging moisturizer provides broad spectrum SPF 25 protection. (
  • If you prefer to be cautious and avoid exposure to parabens, many health and beauty products and food items are now paraben-free, and if paraben compounds are in the product, they'll be listed on the label. (
  • Is Eucerin paraben free? (
  • It is fragrance free and paraben free so it's great for people with sensitive skin. (
  • Is Dove paraben free? (
  • So, the vast majority of our products are already formulated to be paraben-free, and we're working on the rest. (
  • Are there any moisturizers that are free of parabens? (
  • Shampoos that where developed for hair extensions will be FREE of Parabens, Sulphates, and Sodium Chloride (Salt). (
  • Here are some reasons why you should make the switch to any our paraben- and sulfate-free shampoos today. (
  • Let's explore some paraben- and sulfate-free shampoos! (
  • If you do decide to stay away from parabens commonly found in creams and are in need for an excellent moisturizing cream free of parabens, consider trying Phyto-C SuperHeal O-Live Cream or Phyto-C Moisturize Cream . (
  • All products are paraben free. (
  • I have been using the leave in conditioner for a couple of years and my wavy hair has def thrived and now being sulfate and paraben free even better. (
  • I've been using this product for years and I'm so happy to finally have one that's sulfate, paraben, and silicone free. (
  • The US Food and Drug Administration has no such bans in effect but have stated that they intend to continue rigorous research into the safety of parabens. (
  • Safety assessments support the safety of parabens in cosmetic products at these thresholds. (
  • Parabens are man-made chemicals often used in small amounts as preservatives in cosmetics, pharmaceuticals, foods, and beverages. (
  • In 2006, the industry-led Cosmetic Ingredient Review (CIR), in a partnership with the U.S. Food and Drug Administration (FDA), determined that there was no need to change CIR's original conclusion from 1984 that parabens are safe for use in cosmetics. (
  • Parabens are short alkyl chain esters of para-hydroxybenzoic acid (PHBA) that are widely used as preservatives in pharmaceuticals, cosmetics and in such personal care products as shampoos, hair and shaving products, facial and skin cleansers, and lotions. (
  • The preservatives used in cosmetics and personal care products have been at the root of the cosmetic industry's controversy, but there has never been enough substantial evidence to deem parabens completely unsafe. (
  • Even so, many people in the beauty industry have been weary of parabens since the Campaign for Safe Cosmetics alleged that they are linked to cancer, endocrine disruption, reproductive toxicity, immunotoxicity, neurotoxicity and skin irritation. (
  • And while estrogenic activity in the body is associated with certain forms of breast cancer, parabens have been shown to have much less estrogenic activity than the body's naturally occurring estrogen.The FDA website says: "FDA believes that at the present time there is no reason for consumers to be concerned about the use of cosmetics containing parabens. (
  • Parabens, esters of p-hydroxybenzoic acid, are used as preservatives in cosmetics and foods. (
  • In fact, parabens are the most widely used preservatives in the cosmetics industry. (
  • Preservatives like parabens protect cosmetics from the growth of fungus and bacteria. (
  • You've probably been told to stay away from cosmetics & skincare products that contain parabens. (
  • A paraben is a preservative added to personal care products to keep it from going bad or rancid, extending the shelf life of cosmetics and personal care products. (
  • Parabens in nature help fight fungus and bacteria, this is totally different than what is added to our cosmetics and skincare. (
  • The scary truth is that parabens are still allowed in cosmetics. (
  • Since the 1950s, parabens have been used in a variety of cosmetics, foods and drugs, providing protection against bacteria, mold and other microorganisms - not to mention giving products a longer shelf life 3 . (
  • Also, while estrogen plays a role in certain types of breast cancer, there is no proof that parabens cause breast cancer, and no studies to show that breast cancer rates are higher in people who use more paraben-containing cosmetics 3 . (
  • Since parabens are used in many cosmetics, there is a small likelihood that irritation or allergy can occur. (
  • The reporting of adverse events related to paraben-containing products began in the 1940s, and these preservatives have demonstrated very low rates of sensitivity and allergy - despite their extensive use in foods, cosmetics and drugs. (
  • A loose analogy might be that parabens to cosmetics are as chlorine is to swimming pools. (
  • In fact, according to the David Suzuki Foundation , an estimated 75-90% of all cosmetics contain some level of parabens. (
  • According to Dr. Jeanine Downie , a New Jersey-based board-certified dermatologist , parabens are commonly used in cosmetics due to their exceptional antimicrobial activity. (
  • I'll continue to do my best to eat healthily, use natural products , and… skip the parabens. (
  • Parabens are one type of preservative -- they're antifungal agents used in food, pharmaceuticals and skin care products [source U.S. Food and Drug Administration ]. (
  • No parabens, harsh preservative or grapefruit seed extract. (
  • I advise my patients to avoid parabens, especially if they have a history of a sensitivity to skin care products, suffer from eczema or from hives," says Dr. Downie. (
  • Should I Avoid Parabens? (
  • As a result, most people are exposed to parabens from many different sources - every single day. (
  • While allergic reactions to parabens may be one of your worries, the possible link between parabens and cancer probably has you more concerned. (
  • Research shows a possible link between parabens and certain health issues. (
  • This unique, hypoallergenic formula is the perfect choice for people with sensitivities to glycerin and parabens. (
  • Even though the data I discussed earlier was from a small study, 19 out of 20 breast cancer tumors had traces of parabens… scary. (
  • The researchers found traces of parabens in 19 of the 20 women studied. (
  • The EWG's (Environmental Working Group) Skin Deep® database states parabens are linked to cancer, endocrine disruption, reproductive toxicity, immunotoxicity, neurotoxicity, and skin irritation. (
  • Of greatest concern is that parabens are known to disrupt hormone function, an effect that is linked to increased risk of breast cancer and reproductive toxicity. (
  • However, using parabens in a formulation is frowned upon by consumers due to their potential toxicity and carcinogenic properties. (
  • People can be exposed to parabens through touching, swallowing, or eating products that contain parabens. (
  • Parabens in these products are absorbed through the skin. (
  • Parabens (p-hydroxybenzoic acid esters), bisphenols, benzophenone-type UV filters, triclosan, and triclocarban are used in a variety of consumer products, including baby teethers. (
  • The total amount of the sum of six parent parabens (Σ6 Parabens) leached from teethers ranged from 2.0 to 1990 ng, whereas that of their four transformation products (Σ4 Parabens) ranged from 0.47 to 839 ng. (
  • Just to be clear, parabens have been used in products since 1984 and the FDA has continually re-evaluated them. (
  • Parabens are antifungal agents that are used as preservatives in foods, pharmaceuticals and skin care products. (
  • They're used in makeup, hair care products, moisturizers and shaving products, and despite what you may have heard, parabens are rarely used in deodorants and antiperspirants. (
  • If you're worried about parabens, or you think your skin may be reacting adversely to them, it's best to avoid products that contain them. (
  • Because so many products contain parabens, the possibility that they may be linked to cancer has garnered a lot of attention. (
  • The excerpt below from the EWG website explains what parabens are and why we shouldn't use products containing parabens. (
  • Parabens are a group of chemicals widely used as artificial preservatives in cosmetic and body care products since the 1920s. (
  • For me, the threat of danger from exposure to parabens is not a one-time use and an immediate diagnosis of breast cancer, the concern is a slow buildup from using various products containing any toxin on a daily basis that will add up over the years. (
  • Poke around enough and you will find opposing views that parabens don't have anything to do with breast cancer and articles that promise using parabens in small amounts to give products longer shelf life is completely safe. (
  • I have been reading about the dangers of parabens and other additives in skin products and was looking for a new product line that not only didn't include those things, but that took it one step further. (
  • Paraben compounds are also quickly eliminated from the body, although constant use of paraben-containing products will increase the body's lifetime exposure to these compounds. (
  • This has prompted concerns that excessive use of paraben-containing products could lead to early puberty in females, fuel the growth of estrogen receptor-positive breast cancers, or impact fertility in males - causing low sperm counts or decreased levels of testosterone. (
  • Yes, most CeraVe products are formulated with parabens. (
  • What are Parabens and Why are They Used in Beauty Products? (
  • Paraben usage is widespread and can be found in skincare products, hair care products, pharmaceutical drugs and even in our food. (
  • The primary function of parabens is to prevent bacteria and mold from growing within these products. (
  • Parabens are a class of artificial preservatives that are present in a range of cosmetic products. (
  • Commercialized in the 1950s, parabens (an abbreviation of p-hydroxybenzoic acids) are a family of synthetic compounds used extensively as preservatives in a wide range of cosmetic products, including moisturizers , shampoos , and lotions . (
  • Under regulations set out by the Food and Drug Administration (FDA), cosmetic products are currently allowed to contain up to 0.4% for a single ester (type of paraben) and 0.8% for total parabens. (
  • The antimicrobial properties of parabens protect cosmetic products against this degradation, thereby extending their shelf life considerably, while safeguarding consumers against harmful bacteria. (
  • Parabens are a class of chemicals widely used in beauty and self care products. (
  • Parabens can be found in a myriad of personal care products including toothpaste, lotions, and all different kinds of makeup. (
  • Any parabens used in personal care products or for other commercial purposes are synthesized in a lab, though their structure mimics parabens found in nature. (
  • Parabens are preservatives formulated in cosmetic and pharmaceutical products for their bactericidal and fungicidal properties. (
  • Call or email the brand and be sure to ask about the concentration of parabens in their products. (
  • You can call Phyto-C customer service line and speak to one of our representatives who will happily answer any question you may have even though our products do not contain parabens. (
  • Human health effects from environmental exposure to low levels of parabens are unknown. (
  • Biomonitoring of urinary environmental phenols and parabens is used to determine their prevalence in humans and the relevance of human exposure in public health. (
  • Measurement of urinary environmental phenols and parabens is useful to assess recent human exposure. (
  • Although the Food and Drug Administration (FDA) deems current exposure levels safe and without health risks, concerns persist about hormone-disrupting effects and the impact of parabens on health and cancer risk 3 . (
  • Humans are regularly exposed to parabens, but the FDA has concluded that there are no known health effects with current exposure levels. (
  • The FDA continues to review research reports on paraben safety, although current data does not show human exposure rates have an effect on health. (
  • If you stopped your exposure to parabens, your body would be clear within a matter of days. (
  • Therefore, worst-case daily exposure to parabens would present less risk compared to naturally occurring chemicals found in the diet. (
  • Paraben exposure and couple fecundity: a preconception cohort study. (
  • The concern with these chemicals is that scientific studies suggest that parabens can disrupt hormones in the body and harm fertility and reproductive organs, affect birth outcomes, and increase the risk of cancer. (
  • That being said, there are several studies that show parabens to have both estrogenic and androgenic (think testosterone) properties which means they have the ability to disrupt our body's receptors for estrogen and testosterone - not good. (
  • The idea that they cause cancer is supported mainly by the fact that parabens have the ability to disrupt the endocrine system and other endocrine disrupting chemicals have actually been linked to cancer. (
  • Method for separation of methyl paraben, propyl paraben, benzonitrile and toluene was developed on a Obelisc R column. (
  • In adults younger than age 60, non-Hispanic blacks had higher levels of methyl paraben than non-Hispanic whites. (
  • Parabens occur naturally and commonly found in bacteria, insects, and royal jelly. (
  • We have developed a sensitive method for measuring BPA, 4-tert-octylphenol (tOP), benzophenone-3 (BP-3), one chlorophenols triclosan, and four parabens. (
  • By measuring these chemicals in urine, scientists can estimate the amount of parabens that has entered people's bodies. (
  • This small study does not prove a causal relationship between parabens and breast cancer, but it is important because it detected the presence of intact parabens - unaltered by the body's metabolism - which is an indication of the chemicals' ability to penetrate skin and remain in breast tissue. (
  • Parabens can irritate skin or cause allergic skin reactions. (
  • If you're allergic to parabens, contact dermatitis can occur in skin. (
  • One of the most common side effects of parabens is that they can induce an allergic reaction , particularly among people that have existing skin conditions. (
  • According to WWD , in meetings over the past few days the Cosmetic Ingredient Review has re-evaluated parabens and have deemed them safe once again. (
  • The removal of parabens by some cosmetic manufacturers is a reaction to "outrageous claims" made by the media and pressure from non-governmental organisations (NGOs), not consumer pressure, according to Dene Godfrey from S Black. (
  • Parabens are common preservatives in pharmaceutical and cosmetic industries. (
  • In addition, there is no evidence that parabens cause other reproductive harm in humans. (
  • There are several studies that suggest parabens could have an adverse effect on the male reproductive system, and sperm quality in particular. (
  • A 2005 study concluded it is highly unlikely that parabens could increase the health risk of the effects on the male reproductive tract or breast cancer. (
  • Parabens also occur naturally in some foods, including specific fruit juices and wine. (
  • Parabens occur naturally in many foods such as wine and some fruit juices. (
  • The estrogenic activity of parabens increases with the length of the alkyl group. (
  • More research is needed to accurately address these concerns and to understand any impact paraben compounds have on health. (
  • Parabens are synthetic compounds that are used as preservatives. (
  • This prospect naturally alarms many people -- especially because parabens are such a common ingredient. (
  • Butyl Paraben by Acme Hardesty Co. (
  • Butyl Paraben is a long-chained paraben in the form of a white, crystalline powder. (
  • Butyl Paraben can be used alone or combined with other parabens in a blend, and is used in toothpaste, mascara, lipstick, and eyeshadow. (
  • Centers for Disease Control and Prevention scientists measured parabens in the urine of more than 2,548 participants aged six years and older who took part in the National Health and Nutrition Examination Survey (NHANES) during 2005-2006. (
  • Finding a measurable amount of parabens in urine does not imply that they cause an adverse health effect. (
  • After parabens are absorbed in the body, they are rapidly hydroyzed and then conjugated to glucuronide or sulfate and eliminated in the urine. (
  • Moreover, studies have detected parabens in nearly all urine samples taken from adults in the U.S., regardless of demographic (Ye 2006). (
  • Most of the safety concerns about parabens are related to their role as endocrine disruptors, which are substances that, at certain doses and in specific conditions, can interfere with the activity of hormones within the body. (
  • In addition to being harsh to skin, many experts believe that parabens may be associated with a variety of health problems and adverse side effects. (
  • Read on to learn exactly what parabens are and why they're so commonly used. (
  • Parabens may be a common defense of plants against bacterial or fungal infections. (
  • Less than 3% of patients tend to have sensitivity to parabens among people with contact dermatitis. (
  • Take a look at the ingredient list of your favorite beauty or personal care product and there is a very high probability you will see parabens listed. (
  • Whatever had parabens in them I tossed (except for the eczema cream because I haven't found an alternative to that yet. (
  • If you suffer from an existing skin condition like eczema, dermatitis, or psoriasis, the use of parabens can aggravate your skin and make matters worse. (
  • If you have psoriasis, eczema, rosacea or any other skin issue that affects skin sensitivity, you may want to consider avoiding parabens. (