Methyl, propyl, butyl, and ethyl esters of p-hydroxybenzoic acid. They have been approved by the FDA as antimicrobial agents for foods and pharmaceuticals. (From Hawley's Condensed Chemical Dictionary, 11th ed, p872)
Substances added to pharmaceutical preparations to protect them from chemical change or microbial action. They include ANTI-BACTERIAL AGENTS and antioxidants.
Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
Substances capable of inhibiting, retarding or arresting the process of fermentation, acidification or other deterioration of foods.
Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.
Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
A diphenyl ether derivative used in cosmetics and toilet soaps as an antiseptic. It has some bacteriostatic and fungistatic action.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in water, sewage, soil, meat, hospital environments, and on the skin and in the intestinal tract of man and animals as a commensal.
A class of MOLECULAR CHAPERONES whose members act in the mechanism of SIGNAL TRANSDUCTION by STEROID RECEPTORS.
Sequential operating programs and data which instruct the functioning of a digital computer.
Agents that remove, correct, repress, or mask undesirable ODORS. In personal hygiene, deodorants often contain astringent preparations that reduce SWEATING, referred to as ANTIPERSPIRANTS. (From Grant & Hackh's Chemical Dictionary, 5th ed)
Deciduous plant rich in volatile oil (OILS, VOLATILE). It is used as a flavoring agent and has many other uses both internally and topically.
Cyclic compounds with a ring size of approximately 1-4 dozen atoms.

Synergistic protective effects of antioxidant and nitric oxide synthase inhibitor in transient focal ischemia. (1/220)

Both nitric oxide synthase (NOS) inhibitors and free radical scavengers have been shown to protect brain tissue in ischemia-reperfusion injury. Nitric oxide and superoxide anion act via distinct mechanisms and react together to form the highly deleterious peroxynitrite. Therefore the authors examined the effects and the interaction between the NOS inhibitor, NG nitro-L-arginine (LNA) and the antioxidant/superoxide scavenger, di-tert-butyl-hydroxybenzoic acid (DtBHB) in the rat submitted to 2 hours of middle cerebral artery occlusion. Posttreatment was initiated 4 hours after the onset of ischemia and infarct volume was measured at 48 hours. The dose-related effect of LNA resulted in a bell-shaped curve: 15, 56, 65, and 33% reduction of total infarct for 0.03, 0.1, 0.3, and 1 mg/kg (intravenously [IV]) respectively and 11% increase in infarct volume for 3 mg/kg (IV). Whereas DtBHB (20 mg/kg; intraperitoneally [IP]) was ineffective, the dose of 60 mg/kg produced 65% protection in infarct volume. The combination of a subthreshold dose of LNA (0.03 mg/kg; IV) and DtBHB (20 mg/kg; IP) resulted in significant reduction (49%) in infarct volume. These results show that LNA and DtBHB act synergistically to provide a consistent neuroprotection against ischemic injury when administered 4 hours after ischemia. This suggests that nitric oxide and free radicals are involved and interact in synergy in ischemia-reperfusion injury.  (+info)

Effect of neonatal exposure to estrogenic compounds on development of the excurrent ducts of the rat testis through puberty to adulthood. (2/220)

Neonatal exposure to diethylstilbestrol (DES) can alter the structure of the testicular excurrent ducts in rats. We characterized these changes according to dose and time posttreatment and established whether potent estrogens (ethinyl estradiol), environmental estrogens (genistein, octylphenol, bisphenol A, parabens), and tamoxifen induce such changes. Rats were administered these compounds neonatally and assessed at several time points during (day 10, or day 18 for some treatments) and after (days 18, 25, 35, and 75) the treatment period to detect any changes in testis weight, distension of the rete testis and efferent ducts, epithelial cell height in the efferent ducts, and immunoexpression of the water channel aquaporin-1 (AQP-1). Treatment with DES (10, 1, or 0.1 microg/injection; equivalent to 0.37, 0.037, or 0.0037 mg/kg/day, respectively) induced dose-dependent changes in testis weight and all parameters. These effects were most pronounced at days 18 and 25 and appeared to lessen with time, although some persisted into adulthood. Neonatal treatment with ethinyl estradiol (10 microg/injection; equivalent to 0.37 mg/kg/day) caused changes broadly similar to those induced by 10 mg DES. Administration of tamoxifen (2 mg/kg/day) caused changes at 18 days that were similar to those induced by 1 microg DES. Treatment with genistein (4 mg/kg/day), octylphenol (2 mg/injection; equivalent to 150 mg/kg/day), or bisphenol A (0.5 mg/injection; equivalent to 37 mg/kg/day) caused minor but significant (p<0.05) decreases in epithelial cell height of the efferent ducts at days 18 and/or 25. In animals that were followed through to 35 days and/or adulthood, these changes were no longer obvious; other parameters were either unaffected or were affected only marginally and transiently. Administration of parabens (2 mg/kg/day) had no detectable effect on any parameter at day 18. To establish whether these effects of estrogens were direct or indirect (i.e., resulting from reduced follicle-stimulating hormone/luteinizing hormone secretion), the above end points were assessed in animals in which gonadotropin secretion was suppressed neonatally by administration of a gonadotropin-releasing hormone antagonist. This treatment permanently reduced testis weight, but did not affect any of the other end points, apart from a minor transient reduction in efferent duct epithelial cell height at 18 days. This study suggests that structural and functional (expression of AQP-1) development of the excurrent ducts is susceptible to impairment by neonatal estrogen exposure, probably as a consequence of direct effects. The magnitude and duration of adverse changes induced by treatment with a range of estrogenic compounds was broadly comparable to their estrogenic potencies reported from in vitro assays.  (+info)

Cloning and sequencing of the fcbB gene encoding 4-chlorobenzoate-coenzyme A dehalogenase from Pseudomonas sp. DJ-12. (3/220)

Pseudomonas sp. DJ-12 degrades 4-chlorobenzoate through hydrolytic dechlorination to produce 4-hydroxybenzoate and a chloride ion. The fcbB gene encoding the 4-chlorobenzoate-coenzyme A (4CBA-CoA) dehalogenase which catalyzes the nucleophilic substitution reaction to convert 4CBA-CoA to 4-hydroxybenzoate-coenzyme A (4HBA-CoA) in the consecutive steps of dechlorination was cloned from the chromosome of the organism. A nucleotide sequence analysis of the gene showed an open reading frame consisting of 810 nucleotides, which can encode for a polypeptide of molecular mass 30 kDa, containing 269 amino acid residues. A promoter-like sequence (-35 and -10 region) and a putative ribosome-binding sequence were identified. A deduced amino acid sequence of the 4CBA-CoA dehalogenase showed 86%, 50%, and 50% identity with those of corresponding enzymes in the Pseudomonas sp. CBS3, Arthrobacter sp. SU, and Arthrobacter sp. TM1, respectively.  (+info)

Conserved cytoplasmic loops are important for both the transport and chemotaxis functions of PcaK, a protein from Pseudomonas putida with 12 membrane-spanning regions. (4/220)

Chemotaxis to the aromatic acid 4-hydroxybenzoate (4-HBA) by Pseudomonas putida is mediated by PcaK, a membrane-bound protein that also functions as a 4-HBA transporter. PcaK belongs to the major facilitator superfamily (MFS) of transport proteins, none of which have so far been implicated in chemotaxis. Work with two well-studied MFS transporters, LacY (the lactose permease) and TetA (a tetracycline efflux protein), has revealed two stretches of amino acids located between the second and third (2-3 loop) and the eighth and ninth (8-9 loop) transmembrane regions that are required for substrate transport. These sequences are conserved among most MFS transporters, including PcaK. To determine if PcaK has functional requirements similar to those of other MFS transport proteins and to analyze the relationship between the transport and chemotaxis functions of PcaK, we generated strains with mutations in amino acid residues located in the 2-3 and 8-9 loops of PcaK. The mutant proteins were analyzed in 4-HBA transport and chemotaxis assays. Cells expressing mutant PcaK proteins had a range of phenotypes. Some transported at wild-type levels, while others were partially or completely defective in 4-HBA transport. An aspartate residue in the 8-9 loop that has no counterpart in LacY and TetA, but is conserved among members of the aromatic acid/H(+) symporter family of the MFS, was found to be critical for 4-HBA transport. These results indicate that conserved amino acids in the 2-3 and 8-9 loops of PcaK are required for 4-HBA transport. Amino acid changes that decreased 4-HBA transport also caused a decrease in 4-HBA chemotaxis, but the effect on chemotaxis was sometimes slightly more severe. The requirement of PcaK for both 4-HBA transport and chemotaxis demonstrates that P. putida has a chemoreceptor that differs from the classical chemoreceptors described for Escherichia coli and Salmonella typhimurium.  (+info)

Effects of atovaquone and diospyrin-based drugs on ubiquinone biosynthesis in Pneumocystis carinii organisms. (5/220)

The naphthoquinone atovaquone is effective against Plasmodium and Pneumocystis carinii carinii. In Plasmodium, the primary mechanism of drug action is an irreversible binding to the mitochondrial cytochrome bc(1) complex as an analog of ubiquinone. Blockage of the electron transport chain ultimately inhibits de novo pyrimidine biosynthesis since dihydroorotate dehydrogenase, a key enzyme in pyrimidine biosynthesis, is unable to transfer electrons to ubiquinone. In the present study, the effect of atovaquone was examined on Pneumocystis carinii carinii coenzyme Q biosynthesis (rather than electron transport and respiration) by measuring its effect on the incorporation of radiolabeled p-hydroxybenzoate into ubiquinone in vitro. A triphasic dose-response was observed, with inhibition at 10 nM and then stimulation up to 0.2 microM, followed by inhibition at 1 microM. Since other naphthoquinone drugs may also act as analogs of ubiquinone, diospyrin and two of its derivatives were also tested for their effects on ubiquinone biosynthesis in P. carinii carinii. In contrast to atovaquone, these drugs did not inhibit the incorporation of p-hydroxybenzoate into P. carinii carinii ubiquinone.  (+info)

HbaR, a 4-hydroxybenzoate sensor and FNR-CRP superfamily member, regulates anaerobic 4-hydroxybenzoate degradation by Rhodopseudomonas palustris. (6/220)

Under anaerobic conditions, structurally diverse aromatic compounds are catabolized by bacteria to form benzoyl-coenzyme A (benzoyl-CoA), the starting compound for a central reductive pathway for aromatic ring degradation. The structural genes required for the conversion of 4-hydroxybenzoate (4-HBA) to benzoyl-CoA by Rhodopseudomonas palustris have been identified. Here we describe a regulatory gene, hbaR, that is part of the 4-HBA degradation gene cluster. An hbaR mutant that was constructed was unable to grow anaerobically on 4-HBA. However, the mutant retained the ability to grow aerobically on 4-HBA by an oxygen-requiring pathway distinct from the anaerobic route of 4-HBA degradation. The effect of the HbaR protein on expression of hbaA encoding 4-HBA-CoA ligase, the first enzyme for 4-HBA degradation, was investigated by using hbaA::'lacZ transcriptional fusions. HbaR was required for a 20-fold induction of beta-galactosidase activity that was observed with a chromosomal hbaA::'lacZ fusion when cells grown anaerobically on succinate were switched to anaerobic growth on succinate and 4-HBA. HbaR also activated expression from a plasmid-borne hbaA-'lacZ fusion when it was expressed in aerobically grown Pseudomonas aeruginosa cells, indicating that the activity of this regulator is not sensitive to oxygen. The deduced amino acid sequence of HbaR indicates that it is a member of the FNR-CRP superfamily of regulatory proteins. It is most closely related to transcriptional activators that are involved in regulating nitrate reduction. Previously, it has been shown that R. palustris has an FNR homologue, called AadR, that is also required for 4-HBA degradation. Our evidence indicates that AadR activates expression of hbaR in response to anaerobiosis and that HbaR, in turn, activates expression of 4-HBA degradation in response to 4-HBA as an effector molecule.  (+info)

Methyl p-hydroxybenzoate (E-218) a preservative for drugs and food is an activator of the ryanodine receptor Ca(2+) release channel. (7/220)

1. Haloperidol is a drug used in the management of several psychotic disorders and its use has been linked to Neuroleptic Malignant Syndrome. In the present study we have investigated the effect of a commercial preparation of haloperidol, Serenase, on skeletal muscle sarcoplasmic reticulum. 2. Addition of Serenase to isolated terminal cisternae caused a rapid release of calcium. We tested whether the active Ca(2+)-releasing substance was haloperidol or another compound present in the preparation. 3. Our results show that methyl p-hydroxybenzoate, one of the preservatives and a commonly used anti-microbial agent (E-218) is an activator of Ca(2+) release (E.C. 50=2.0 mM), mediated by a ruthenium red-sensitive Ca(2+) release channel present in skeletal muscle terminal cisternae.  (+info)

Antioxidative galloyl esters as enzyme inhibitors of p-hydroxybenzoate hydroxylase. (8/220)

Gallic acid and its esters were evaluated as enzyme inhibitors of recombinant p-hydroxybenzoate hydroxylase (PHBH), a NADPH-dependent flavin monooxygenase from Pseudomonas aeruginosa. n-Dodecyl gallate (DG) (IC(50)=16 microM) and (-)-epigallocatechin-3-O-gallate (EGCG) (IC(50)=16 microM), a major component of green tea polyphenols, showed the most potent inhibition, while product-like gallic acid did not inhibit the enzyme significantly (IC(50)>250 microM). Inhibition kinetics revealed that both DG and EGCG inhibited PHBH in a non-competitive manner (K(I)=18.1 and 14.0 microM, respectively). The enzyme inhibition was caused by specific binding of the antioxidative gallate to the enzyme, and by scavenging reactive oxygen species required for the monooxygenase reaction. Molecular modeling predicted that EGCG binds to the enzyme in the proximity of the FAD binding site via formation of three hydrogen bonds.  (+info)

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In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. The molar solubility of butyl paraben in pure solvents and its thermodynamic properties, measured by Differential Scanning Calorimetry, have been used to estimate the activity of the pure solid phase, and solution activity coefficients.. More than 5000 nucleation experiments of ethyl paraben, propyl paraben and butyl paraben in ethyl acetate, acetone, methanol, ethanol, propanol and 70%, 90% ethanol aqueous solution have been performed. The induction time of each paraben has been determined at three different supersaturation levels in various solvents. The wide variation in induction time reveals the stochastic nature of nucleation. The solid-liquid interfacial energy, free energy of nucleation, nuclei critical radius and pre-exponential factor of ...
Parabens are used to prevent the growth of microbes in cosmetics products and can be absorbed through skin, blood and the digestive system. Parabens have been found in biopsies from breast tumors at concentrations similar to those found in consumer products. Parabens may be found in a wide variety of products including facial cleansers, shampoos, lotions, deodorants, scrubs and eye makeup, and are found in nearly all urine samples from U.S. adults regardless of ethnic, socioeconomic or geographic backgrounds. Adolescents and adult females had higher levels of methylparaben and propylparaben in their urine than did males of similar ages.. Parabens are actually several distinct chemicals with a similar molecular structure. Four of these are used frequently in cosmetics: ethylparaben, butylparaben, methylparaben and propylparaben. Methylparaben and propylparaben are the most common of these. Parabens are most common in personal care products that contain significant amounts of water, such as ...
In fact, parabens themselves are natural substances found in food and so we are exposed to them through food. Parabens is the name given to a group of p-hydroxybenzoic acid (PHBA) esters. Parabens are biodegradable and natural. A growing number of manufacturers are now using Japanese honeysuckle extract in their products. This is a source of parabens and by using it the manufacturers are getting around the negative public perception of using parabens. We may have done parabens a big disservice and could find that they are actually the best and most natural preservative we can use. Lets keep an open mind on this. Here is more reading on the subject. ...
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I once read, in a comment somewhere related to beauty products, a girl gleefully explain that she loved parabens. I dont want no moldy lotion! ...Sad. Im sure youve heard some of the hype about parabens, and personally, yes, I know that they serve a purpose. But just like so many other chemicals, they are the cheapest way companies tend to deal with the problem, and they are harmful. Parabens act like estrogens in the body. Sure, we all have estrogen. But we shouldnt have extra. On top of everything else, not all estrogens are the same, and because these are alien estrogens, they dont behave the same way in our bodies. They are abundant in beauty and body products, which is really a shame. By the time a woman gets ready in the morning, she has exposed herself to hundreds of harmful chemicals already. High concentrations of estrogens have been found in breast cancer tumors, highlighting estrogens negative impacts on the disease. Parabens have been found to, in a way, feminize mens ...
Parabens are a group of compound used as preservatives in pharmaceutical and cosmetic industry. Parabens are widely used in beauty, skin care and fragrance ingredients to prevent bacteria and fungus growth. These are basically in almost every other product to increase shelf life. It has been estimated that women are daily exposed to 50 mg of paraben from cosmetic use. Continued use of products with parabens are known to be allergic and cause rashes. It easily penetrates in skin. Naturally parabens are found at low levels in certain foods whereas when applied to the skin and absorbed into the body, parabens in cosmetics bypass the metabolic process and enter the blood stream and body organs intact. Commonly found in make up, face and body cleanser, moisturizer and shampoos. Look for Methylparaben, Propylparaben, Isoparaben, Butylparaben on the label.. ...
Parabens are a class of chemicals used as an inexpensive preservative in cosmetics, food and pharmaceuticals. The use in personal care products is widespread and can be found in shampoos, laundry detergents and deodorants. Methylparaben, butylparaben, propylparaben and ethylparaben are commonly used paraben compounds that are found in tens of thousands products in America. Essentially, if you see any combination of words that contains paraben, you can be confident that you should be concerned about the potential negative effects of the product.. Manufacturers may be able to save some expense in the manufacture of their product at the costs to consumer health. Parabens also act as hormone disruptors and possess estrogenic activity. Researchers found that 14 of 17 parabens stimulate human estrogen receptors and that heptylparaben and pentylparaben exhibited the most potent estrogen (alpha and beta) agonist activity.. Nearly a decade ago, researchers found intact parabens accumulating in human ...
What is really surprising is that I went through all the other products I used trying to see if there were parabens in it (thereby proving whether or not parabens was causing the skin condition). The only American product that I used which had parabens in it was the Biore microscrub. I used it again today and noticed the slight skin irritation on my finger which went away in less than a minute (the effect was so brief I usually thought it was caused my the fact I like to wash my face in relatively hot water). So I suppose I am allergic, but it because the paraben was listed so low in the list (usually meaning there is less of it in the product) and that I only use the scrub 2-3 times a week I didnt have a severe enough reaction to know I was allergic. Whereas using the paraben cleanser on my face everyday, twice a day, just killed it ...
Parabens are one of the most widely used preservatives in personal care products, but many health concerns have cropped up over the years. So, should you be worried about slathering them on your skin? Its up for debate. While Marta has taken a stance against the use of parabens in skin care, her friend Nicki Benvenuti, founder and CEO of FutureDerm, sees less cause for concern. Here, they face off: Are parabens really a problem? Keep scrolling to read their discussion.
A few years ago in the world of personal care products, certain buzzwords started circulating in conversations, especially between mumz. Are you using paraben-free products? Did you hear what they are saying about sulfates? and the questions went on and on. All of a sudden, mumz were taking a good look at their own as well as their childrens personal care products, and it all became a little overwhelming and confusing!. Some products had parabens but were sulfate free and vice-versa, some had both, some had neither; which one to get?. Here is what you need to know without the long winded chemical names and the drama!. What are Parabens and are they evil?. Parabens are the most widely used chemical conservatives in cosmetics and personal care products, used to stop microbes like fungus and bacteria growing in your products. Over time, they have been linked to various forms of cancer in both men and women, but no studies to date have confirmed this - in fact, various health institutions ...
We assessed the estrogen agonist activities of 21 parabens and their chlorinated derivatives by using yeast two-hybrid assays incorporating either the human or medaka (Oryzias latipes) estrogen receptor alpha (hERalpha and medERalpha, respectively), and by using hERalpha competitive enzyme-linked immunosorbent assay (ER-ELISA). In the two-hybrid assay with hERalpha, five parabens and three chlorinated derivatives exhibited estrogenic activity, and their relative activity (17beta-estradiol [E2] = 1) ranged from 2.0 x 10(-5) to 2.0 x 10(-4), with the highest activity observed in i-butylparaben. In the medERalpha assay, six parabens and six chlorinated derivatives exhibited estrogenic activity and their relative activity ranged from 2.7 x 10(-5) to 3.5 x 10(-3), with the highest activity observed in benzylparaben, its monochlorinated derivative, i-butylparaben, and n-butylparaben. Although medERalpha demonstrated an activity to E2 that was three times lower than that demonstrated by hERalpha, medERalpha
Great podcast. I started making handmade cosmetics in 2012. I never read the labels on my cosmetics, bath, and beauty products. Now…I cannot buy anything without reading the label. I found that one of the best ways to keep preservatives away from my handmade products is to eliminate any water-based ingredients. I also use airless pumps to dispense my liquid products. I became obsessed with looking up every ingredient on EWGs website. Parabens may not be considered harmful but they do cause certain skin irritations for those with super sensitive skin. If youre using 3-4 everyday products loaded with parabens youre more likely to experience a reaction. My best advice is to stay away from parabens and products that have tons of synthetic ingredients. There are so many options for all-natural products online via Etsy and other Indie websites. I hardly ever buy cosmetics, bath, or beauty products at retail stores anymore.. ...
Introduction Parabens are widely used as antimicrobial preservatives in medicines given to neonates. Some concerns have been raised about the potential of paraben toxicity. To date there have been no studies of the circulating concentrations of methyl paraben (MPB) in babies. This study aimed to describe the relationship between dose of MPB administered and circulating concentrations using a population pharmacokinetic model.. ...
An IQR increase in methyl paraben was associated with a 7.70% increase (95% CI 1.50, 13.90) in SHBG. Furthermore, an IQR increase in butyl paraben as associated with an 8.46% decrease (95% CI 16.92, 0.00) in estradiol, as well as a 9.34% decrease (95% CI −18.31,−0.38) in estradiol/progesterone. Conversely, an IQR increase in butyl paraben was associated with a 5.64% increase (95% CI 1.26, 10.02) in FT4. Progesterone was consistently negatively associated with phenols, but none reached statistical significance. After stratification, methyl and propyl paraben were suggestively negatively associated with estradiol at the first time point (16-20 weeks), and suggestively positively associated with estradiol at the second time point (24-28 weeks).. Conclusions ...
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Toxicokinetics Several studies have been identified that examine the basic toxicokinetics of Methylparaben: - Methylparaben was hydrolysed by both liver and skin microsomal/cytosolic fraction of humans and minipigs. The hydrolysis by human esterases was higher than that observed for minipigs. - High plasma levels and urinary output of free and conjugated p-Hydroxybenzoic acid (metabolite of Methylparaben) in dogs indicate that hydrolysis of the ester linkage and metabolic conjugate constitute the main paths of alteration for Methylparaben. Excretion via urine is almost complete 48 hours after application of 100 mg/kg bw to dogs. - 1 mg Methylparaben/kg bw/d was applied orally to a dog for one year. The rate of urinary excretion in the dog had increased to such an extent that after 24 hours 96% of the dose was recovered in the urine. - Methyl p-hydroxybenzoate sodium salt was administered to rabbits (800 mg/kg bw/d) and urine collected for 24 hours was examined for metabolites. After application ...
TUESDAY, Feb. 11, 2020 (HealthDay News) -- When pregnant women use cosmetics containing parabens, their children may have a greater likelihood of becoming overweight, a new study suggests.. Parabens are chemicals that have long been used as a preservative in cosmetics and body care products. A number of studies have suggested that parabens mimic estrogens in the body and may disrupt the normal function of hormones.. In the new study, researchers found detectable parabens in the urine of pregnant women who used paraben-containing leave-on products every day -- makeup, body lotion or facial moisturizers.. The higher those urinary paraben levels, the more likely it was that a womans child would be overweight by age 8.. A compound called butylparaben stood out: Kids were twice as likely to be overweight when their mothers prenatal levels of butylparaben were in the top one-third, compared to the bottom third. Girls, it seemed, were more affected than boys.. The findings do not prove that ...
Janice Carol Cosmetics offers a wide range of beauty products that are paraben free and are made from natural ingredients. The companys range of cosmetics includes skin cleansers, scrubs, blush, foundation, eyeliners, eye shadows, lip gloss, and lipstick.. What makes Janice Carol Cosmetics stand out from the crowd is that all their products are free from parabens; chemicals used by 85% of all other cosmetics companies to stop mold and microbes growing in products. However, parabens have been found to cause health issues in women. Parabens are xenoestrogens, which mimic female hormones and confuse the body into thinking its producing too much estrogen causing imbalances in the endocrine system.. The hormonal imbalances caused by Parabens then lead to health issues and disorders including infertility, thyroid problems, and even problems during pregnancy. More worryingly, Parabens have been found to be linked with breast cancer.. Against this backdrop, Janice Carol seized the opportunity to found ...
The pastry youre thinking about buying may contain the preservative propyl paraben, linked to disruptions in hormone signaling.
What should be the use of parabens and preservatives in cosmetic skincare? Why all the fuss about parabens? If you want to learn what this means for you, read this blog!
Q. Many commonly sold lubricants have parabens and other toxic ingredients in them-what sort of impact can inserting these types of ingredients into the body have on the female reproductive system?. A. Using lubricants with toxic ingredients has an effect on our reproductive system, as the vagina and anus are highly permeable areas and anything that is applied topically can be absorbed into the body. Parabens are a very common preservative in most cosmetics (moisturizers, face wash, lotions) that are used to prevent bacterial overgrowth. The problem is that parabens are endocrine disruptors, which means that they have an estrogenic effect in the body-they bind to the same cell receptors as our own estrogen but they interfere with our normal, rhythmic, hormonal process. Exposure to parabens has been associated with cancer and reproductive health issues and hormone imbalances like fibroids, endometriosis, infertility, and PMS.. Parabens have actually been found inside breast tumor cells. And while ...
0095] The composition may further comprise antimicrobial agents such as preservatives or antifungal agents chosen from alcohols, suitable for containing one or a plurality of aromatic substituents, for example phenoxyethanols such as 2-phenoxyethanol, 1-phenoxy-2-propanol, benzyl alcohol, 2-hydroxybiphenyl, parabens, such as methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, sodium methylparaben, sodium ethylparaben, sodium propylparaben, sodium isobutylparaben, sodium butylparaben or sodium isobutylparaben, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethylglycinate, halogenated derivatives such as iodopropynyl butylcarbamate, 2-bromo-2-nitropropan-1,3-diol, 2,4,4-trichloro-2-hydroxydiphenylether (triclosan), 3,4,4-trichlorocarbanilide (triclocarban), chlorbutanulum, 2,4-dichlorobenzyl alcohol, N-(4-chlorophenyl-N-(3,4-dichlorophenyl urea, 1,2-dibromo-2,4-dicyanobutane, chloroxylenol, ketoconazole, oxiconazole, butoconazole, clotrimazole, econazole, ...
How to know if your skin care products contain parabens and what to do. You may have heard of these sneaky little preservatives called parabens. They
BACKGROUND: Biobank serum samples from longitudinal mother-child cohorts have been used to estimate prenatal exposures to endocrine disrupting chemicals (EDCs). However, the knowledge about variations in serum concentrations of non-persistent chemicals during pregnancy is limited.. OBJECTIVE: To describe the within- and between-person variations in serum concentrations of non-persistent chemicals and changes over trimesters, including phthalate metabolites, parabens, phenols, and UV filters.. DESIGN: Longitudinal study with repeated blood samples from 128 healthy pregnant women during pregnancy.. SETTING: Population based study at a University Hospital in Copenhagen 1999-2001.. METHODS: 503 repetitive prenatal serum samples from 128 pregnant women taken at approximately gestational week 12, 20, 30 and 40 were analyzed for 7 UV filters, 32 metabolites of 15 phthalate diesters, 8 phenols and 7 parabens by LC-MS/MS.. RESULTS: Ten of 32 phthalate metabolites from six out of 15 phthalate diesters, ...
Recent research has made us realise just how important it is to read all labels - and not just on the foods we are buying. A new study has now shown how parabens (found in numerous drugs, foods, personal care products and cosmetics) are detected in different parts of our bodies and which areas are the most sensitive to these parabens.
Through lotions, shampoos and other personal care products (PCPs), infants and toddlers are likely becoming exposed to potentially harmful substances, called parabens, at an even higher level than adult women in the U.S., researchers have reported. They published their findings on parabens, which have been linked to reproductive and other health issues, in the ACS…
The bottom line is that all we can do is educate ourselves on the ingredients were are putting into our bodies. How many of us ignore those long lists of unpronounceable ingredients on our products, blissfully washing or eating whatever it may be, without having any idea what that ingredient even does or where it comes from? The lesson is this: education is key, especially when it comes to how we take care of our selves. Hopefully you have learned something new about Parabens from this article and can come to an opinion about them that you are comfortable with. No matter what your personal opinion, the world of skin care is vast, and we have something for everyone here at Sanctuary Spa. Whether you feel safe using products with Parabens, or if you are the all-organic type, we can help you find a skin care regimen that meets your needs and goals! For those of you on the Prosecuting side, ask about our organic skin care line and facial by Eminence Organics! Safe, natural, with no harmful chemicals ...
Bye Bye Parabens is a hair care product line for naturally curly hair. Shampoo, Conditioners, Styling Aids, and Treatments all made for naturally curly hair. Dont worry, all of the products are PARABENS FREE.. Email: [email protected] ...
Over the years, parabens have gained a bit of a bad rep. Studies say one thing, newspapers say another. So, whats the real truth about parabens in our beauty products? Kate Shapland explains it all...
Pret Subrina Professional PHI Colour sampon dupa vopsire (0% Parabens, Formaldehyde Releasers) 1000 ml Original. Cumpara acum Subrina Professional PHI Colour sampon dupa vopsire (0% Parabens, Formaldehyde Releasers) 1000 ml la pretul de 49 lei. Produsele din gama Subrina Professional PHI sunt Originale si se afla pe stoc. Cod produs SUBPHCW_KSHA30. Plasati o comanda online de peste 100 lei si primiti un cadou gratuit. Cosmetice si Parfumuri Subrina Professional PHI Originale si Ieftine. Produse Subrina Professional PHI pentru femei si barbati la cel mai bun pret.. ...
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Creative-Proteomics offer cas 99-76-3 METHYL PARABEN (METHYL 4-HYDROXYBENZOATE) (RING-13C6, 99%) 1 MG/ML IN METHANOL. We are specialized in manufacturing Stabel Isotope Labeled Analytical Standard products.
Product Description• A combination of placenta and herbal extracts• Reduces wrinkle and helps heal scars• Suitable as a day creamDescriptionPlacenta Herbal Complex™ is a sophisticated cream designed to moisturise, revive and protect the skin from harsh environment. It contains placenta extract, aloe vera and jojoba extracts to soothe and heal the skin whilst vitamin E ensures deep hydration. It is also excellent as a day cream as it contains added sunscreen.Ingredients / Active IngredientsIngredients: Water Purified, Caprylic/Capric Triglyceride, Stearic Acid, Glycerin, Cyclomethicones, Stearyl Alcohol, Ceteareth-20, Propylene Glycol, Phenyl Trimethicone, Cetyl Alcohol, Octyl Methoxycinnamate, Jojoba Oil, Dimethicone, Alpha Tocopheryl Acetate, Phenoxyethanol, Methyl Paraben, Propyl Paraben, Ethyl Paraben, Butyl Paraben, Aloe Vera Extract, Triethanolamine, Carbomer, Xanthan Gum, Butylated Hydroxytoluene, Sheep Placental Extract, Liposomes.DirectionsGently smooth on face and neck twice daily.
The results of an inter/intra-laboratory study into a test and reference reaction for isothermal microcalorimeters, the imidazole catalysed hydrolysis of triacetin, have been reported in a recent paper [Thermochim. Acta 380 (2001) 13]. The results and conclusions drawn from this study have been extended to a consideration of the need for a similar test and reference reaction for isothermal microcalorimeters operating in flow mode. This paper reports the findings of a preliminary inter/intra-laboratory study of the base catalysed hydrolysis of methyl 4-hydroxy benzoate (methyl paraben) and its suitability as a test and reference reaction. The derived values for the hydrolysis reaction were (3.15 +/- 0.11) x 10(-4) s(-1) and -50.5 +/- 4.3 kJ mol(-1) for the rate constant and enthalpy, respectively. It is also reported how such a test and reference reaction can be used to validate the thermal output from a LKB 10-700-1 and Thermometric Thermal Activity Monitor (TAM) 2277-202 flow ...
These preservatives are contained in almost all creams. Yes, this makeup will give you the desired effect, but will have to pay for your beauty. Parabens are most often associated with the risk of developing breast cancer. At high concentrations and the interaction with UVB rays the negative impact will be much higher. Although some scholars argue that in the makeup parabens not so much that they can not in any way affect human health. To learn about them, composed by the legend: Butylparaben, Propylparaben, Ethylparaben, methylparaben is.. ...
Instructions for use: Squeeze a pea-size amount onto your toothbrush Add water, brush and rinse 75ml/3.8 fl.oz. Ingredients: Aquatic Mint: Aluminum Hydroxide, Aqua (Water), Sorbitol, Glycerin, Silica, Aroma (Flavor), Cellulose Gum, Sodium Laureth Sulfate, Titanium Dioxide, Sodium Lauryl Sulfate, Citric Acid, Sodium Flouride, Sodium Saccharin, Phenoxyethanol, Imidazolidinyl Urea, Methylparaben, Propylparaben, Ethylparaben, Butylparaben, Hydroxycitronellal, Farnesol Classic Strong Mint: Aluminum Hydroxide, Aqua (Water), Sorbitol, Glycerin, Silica, Aroma (Flavor), Cellulose Gum, Sodium Laureth Sulfate, Titanium Dioxide, Sodium Lauryl Sulfate, Citric Acid, Sodium Fluoride, Sodium Saccharin, Phenoxyethanol, Imidazolidinyl Urea, Methylparaben, Propylparaben, Ethylparaben, Butylparaben, Eugenol, Limonene Whitening Mint: Glycerin, Hydrated Silica, Aqua (Water), Tetrapotassium Pyrophosphate, PEG-32, Sodium Lauryl Sulfate, Aroma (Flavor), Cellulose Gum, Xylitol, Titanium Dioxide, Sodium
Ethylparaben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Its formula is HO-C6H4-CO-O-CH2CH3. It is a member of the class of compounds known as parabens. ...
Parabens are preservative ingredients found in many cosmetic and hair products, but what do they actually do to your skin and hair?
Parabens are chemicals contained in everyday personal care products. They can cause cellular damage, allergies and disrupt the endocrine system. Learn why theyre toxic and how to avoid them.
Studies have shown that parabens are endocrine disruptors, they interfere with our natural hormones, and theyve been found in breast cancer tumors.
TY - JOUR. T1 - Prenatal phenol and paraben exposures in relation to child neurodevelopment including autism spectrum disorders in the MARBLES study. AU - Barkoski, Jacqueline M.. AU - Busgang, Stefanie A.. AU - Bixby, Moira. AU - Bennett, Deborah. AU - Schmidt, Rebecca J.. AU - Barr, Dana Boyd. AU - Panuwet, Parinya. AU - Gennings, Chris. AU - Hertz-Picciotto, Irva. PY - 2019/12. Y1 - 2019/12. N2 - Background: Environmental phenols and parabens are endocrine disrupting chemicals (EDCs) with the potential to affect child neurodevelopment including autism spectrum disorders (ASD). Our aim was to assess whether exposure to environmental phenols and parabens during pregnancy was associated with an increased risk of clinical ASD or other nontypical development (non-TD). Methods: This study included mother-child pairs (N = 207) from the Markers of Autism Risks in Babies - Learning Early Signs (MARBLES) Cohort Study with urinary phenol and paraben metabolites analyzed using liquid ...
Climax Bursts Lubricants are glycerin-free, enriched with vitamin E and water based. The climax beads burst on contact for erotic sensations. The problem is that the contain Parabens. These have been found to cause health problems and is why we will not carry their products until they change this. We do carry paraben free, glycerin lubricants.
Separation of Methyl Paraben, analytical standard; Ethylparaben, United States Pharmacopeia (USP) Reference Standard; Propylparaben, United States Pharmacopeia (USP) Reference Standard; Butylparaben, United States Pharmacopeia (USP) Reference Standard
Propylparaben - is the propyl ester of p-hydroxybenzoic acid and occurs as a natural substance found in many plants and some insects, although it is also manufactured synthetically for use in cosmetics, pharmaceuticals and foods. It is used as a preservative for its anti-fungal and anti-microbial properties to extend the shelf life of beauty and cosmetic products, considered non-toxic, non-sensitizing and non-irritating at .05 to 1% concentrations. This is a paraban and many studies have found a link between parabens and breast cancer ...
According to new research, Parabens, a form of preservative widely used in cosmetic and pharmaceutical products, have begun showing up in the tissues of various marine mammal species, including dolphins, sea otters and polar bears. The preservative is found in shampoos, commercial moisturisers, shaving gels, personal lubricants, topical/parenteral pharmaceuticals, spray tanning solution, makeup, and toothpaste and is used to prevent bacterial growth…
... , also methyl paraben, one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO). It is ... "Toxicity and Estrogen Effects of Methyl Paraben on Drosophila melanogaster". Food Science. 30 (1): 252-254. "Parabens". Food ... Soni MG, Taylor SL, Greenberg NA, Burdock GA (October 2002). "Evaluation of the health aspects of methyl paraben: a review of ... Okamoto Y, Hayashi T, Matsunami S, Ueda K, Kojima N (August 2008). "Combined activation of methyl paraben by light irradiation ...
Fransway, AF; Fransway, PJ; Belsito, DV (2019). "Parabens". Dermatitis. 30 (1): 3-31. doi:10.1097/DER.0000000000000429. PMID ... Parabens (Non) Allergen 2018 - Propylene Glycol 2017 - Alkyl Glucoside 2016 - Cobalt 2015 - Formaldehyde 2014 - Benzophenones ...
Long-chained parabens, like butylparaben, are more estrogenic than short-chained parabens, like methyl- or ethylparaben. This ... In most cosmetics paraben is used at low levels, ranging from 0.01 to 0.3%. Butylparaben is used in low concentrations in ... However, parabens have not been proven to cause breast cancer. Estimates by the U.S. Food and Drug Administration and the ... Members of the paraben family are found in fruit and vegetable products, such as barley, flax seed, and grapes. Butylparaben ...
Parabens can cause skin irritation and contact dermatitis in individuals with paraben allergies, a small percentage of the ... Byford JR, Shaw LE, Drew MG, Pope GS, Sauer MJ, Darbre PD (January 2002). "Oestrogenic activity of parabens in MCF7 human ... Animal experiments have shown that parabens have a weak estrogenic activity, acting as xenoestrogens. Perfumes are widely used ... Nagel JE, Fuscaldo JT, Fireman P (April 1977). "Paraben allergy". JAMA. 237 (15): 1594-5. doi:10.1001/jama.237.15.1594. PMID ...
Furthermore, some of them contain parabens. Parabens are preservatives that can affect the endocrine system. Indoor tanning ... Harvey, Philip W.; Everett, David J. (2004). "Significance of the detection of esters of p-hydroxybenzoic acid (parabens) in ...
Darbre PD, Aljarrah A, Miller WR, Coldham NG, Sauer MJ, Pope GS (2004). "Concentrations of parabens in human breast tumours". J ... parabens (lotions) phthalates (plasticizers) DEHP (plasticizer for PVC) Propyl gallate (used to protect oils and fats in ...
... is a paraben. Isopropylparaben has been prepared via the stepwise addition of isopropanol, thionyl chloride, ...
Its net weight is usually 4 grams (0.14 oz). When manufactured by Wyeth, Chapstick contained no parabens. ChapStick functions ...
Nguyen, T.; Clare, B.; Martinac, B.; Martinac, Boris (2005). "The effects of parabens on the mechanosensitive channels". Eur. ...
CS1 maint: discouraged parameter (link) "Parabens Evelina Coelho". sapo.pt. Retrieved 31 December 2015. CS1 maint: discouraged ...
It is a member of the class of parabens. It is a preservative typically found in many water-based cosmetics, such as creams, ... Directorate-General for Consumer Safety, European Union (2011). "Scientific Committee on Consumer Safety Opinion on Parabens ... "Effects of propyl paraben on the male reproductive system". Food and Chemical Toxicology. 40 (12): 1807-13. doi:10.1016/s0278- ...
... does not use parabens, mineral oil, synthetic fragrances or gluten in their products. Parabens are excluded ... "Should People Be Concerned about Parabens in Beauty Products?". Scientific American. Retrieved 2018-12-13. "3 Key Reasons to ...
The company's cosmetics are not tested on animals; are paraben-free and phthalate-free; and most are vitamin-infused, vegan, ...
P. gergoviae is of special interest to the cosmetics industry, as it displays resistance to parabens, a common antimicrobial ... "Enterobacter gergoviae and the prevalence of efflux in parabens resistance". Journal of Antimicrobial Chemotherapy. 57 (4): 757 ...
Parabens are used to preserve a number of the products. Lush focuses on limited packaging for its product range, or package- ...
All products are sulfate and paraben free.[citation needed] Verrilli began his career in the beauty industry in Sudbury, ...
It is a member of the class of compounds known as parabens. It is used as an antifungal preservative. As a food additive, it ... Ethyl paraben, thegoodscentscompany.com v t e. ...
Some manufacturers are using this preservative as a replacement for parabens. Tube feeding of potassium sorbate reduces the ...
Hormone disruption resulting from the inclusion of parabens as a preservative. Eye irritations should the product accidentally ...
September 2017). "Prenatal exposure to bisphenols and parabens and impacts on human physiology" (PDF). Physiological Research. ...
... (heptyl p-hydroxybenzoate) is a compound with formula C7H15(C6H4OHCOO). It is a paraben which is the heptyl ester ... Parabens". Applied and Environmental Microbiology. 72 (8): 5556. doi:10.1128/AEM.00494-06. PMC 1538717. PMID 16885309. v t e. ...
Bactericidal products such as triclosan (TCS) and parabens kill bacteria on the skin. Alcohols and related compounds such as ... According to the American Cancer Society, "studies have not shown any direct link between parabens and any health problems, ... Another constituent of deodorant products that has given cause for concern are parabens, a chemical additive. ...
The brand is cruelty-free, paraben-free and 100% vegan. Styled as clean, cool beauty the brand has won multiple awards ...
... products are paraben-free, vegan, and cruelty-free. This attracts a vast number of customers to the brand, as well ...
... preparations may contain methylparaben and propylparaben and are inappropriate for use by people with a paraben ... Preservative-free preparations are available for those with paraben hypersensitivities. Naloxone is a lipophilic compound that ...
Preservatives like parabens and benzoates and antioxidants like butylated hydroxytoluene (BHT) and sodium metabisulfite. ...
... parabens, and lanolin. Eczema Ichthyosis Xeroderma pigmentosum Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007 ...
Tropic's products do not contain parabens, alcohol, gluten, synthetic preservatives, or sodium lauryl sulfate. All products are ...
... parabens, UV screens, and musks". J Toxicol Environ Health A. 68 (4): 239-251. doi:10.1080/15287390590895054. PMID 15799449. ...
... is primarily known as the basis for the preparation of its esters, known as parabens, which are used as ... It is a common metabolite of paraben esters, such as methylparaben. The compound is a relatively weak estrogen, but can produce ... common metabolite of paraben esters) and methylparaben in human breast cancer cell lines". Journal of Applied Toxicology. 25 (4 ...
TOXIC BEAUTY 1. Talc 2. Parabens 3. Propylene glycol 4. Mineral oil 5. Sodium lauryl sulfate 6.... ...
The other parabens garnered moderate-high risk ratings from the group.. EXPERT OPINION: "The notion that parabens cause breast ... ALTERNATIVES: If a product doesnt contain parabens, companies will usually mark it "paraben-free," a designation thats more ... Safety profile: Parabens are rumored to be linked to breast cancer. According to Randy Schueller, a cosmetic chemist and the ... However, the study was criticized because it did not prove causation between paraben load and cancer formation, just that the ...
Often more than one paraben is used in a single product.. How People Are Exposed to Parabens. People can be exposed to parabens ... Parabens also can enter the body when pharmaceuticals, foods, and drinks containing parabens are swallowed or eaten. Parabens ... Levels of Parabens in the U.S. Population. Centers for Disease Control and Prevention scientists measured parabens in the urine ... How Parabens Affect Peoples Health. Human health effects from environmental exposure to low levels of parabens are unknown. In ...
This is the talk page for discussing improvements to the Paraben article.. This is not a forum for general discussion of the ... It makes no mention of parabens at all. The anti-perspirant email is already covered in the deodorant article. It doesnt make ... Apparently there have been a series of anonymous edits adding and removing a U.C. Berkley study on Paraben introduced in vitro ... This article infers there was spam email about parabens. The actual cited spam email is about anti-perspirants main mechanism ...
A new study has found that chemicals called parabens can spur the growth of certain types of breast cancer cells. WebMD has the ... Q: Are parabens harmful? Scientists are working hard to understand this. Parabens have a chemical structure thats similar to ... Q: Are the levels of parabens tested in the study like the levels were exposed to in real life? ... Q: Is it possible to avoid some sources of parabens? Yes. Thanks to consumer pressure, more and more cosmetics and personal ...
The pastry youre thinking about buying may contain the preservative propyl paraben, linked to disruptions in hormone signaling ... Propyl paraben is starting to disappear from some cosmetics, so it is a wonder that it is still allowed in food. If you browse ... Last year, EWG turned the spotlight on propyl paraben in its Dirty Dozen Guide To Food Additives because the federal Food and ... Click here today to add your name to EWGs petition and demand that food companies remove propyl paraben from their products. ...
... chlorinated parabens. When paraben-containing products are washed down the drain, parabens have the potential to undergo ... Parabens are esters of para-hydroxybenzoic acid, from which the name is derived. Common parabens include methylparaben (E ... Chlorinated parabens are removed from WWTPs with only 40% efficiency in comparison to 92-98% efficiency of parent parabens. The ... No effective direct links between parabens and cancer have been established. Parabens are active against a broad spectrum of ...
Parabens have been in the news, as they have been linked to breast cancer. This article aims to provide a balanced view of the ... This is an article about parabens, a group of chemicals used in cosmetics as preservatives. ... Should we worry about parabens? Description. This is an article about parabens, a group of chemicals used in cosmetics as ... This is an article about parabens, a group of chemicals used in cosmetics as preservatives. Parabens have been in the news, as ...
... paraben. WHAT ARE PARABENS? Parabens are actually several distinct chemicals with a similar molecular structure. Several are ... Parabens Parabens are preservatives used in a wide variety of personal care products and foods to prevent the growth of ... HOW TO AVOID: Look for products labeled "paraben-free" and read ingredient lists on labels to avoid products with parabens. ... REGULATIONS: Some forms of parabens are banned in Denmark (propyl and butyl paraben, their isoforms and their salts) in ...
Parabens Morgana is hosted at free file sharing service 4shared. Online video hosting. Fast file transfer. Enterprise sharing. ... Parabens Morgana - download at 4shared. Parabens Morgana is hosted at free file sharing service 4shared. ...
Mothers who use beauty products containing chemicals known as parabens during pregnancy may be more likely to have overweight ... Mothers who reported using products known to contain parabens during pregnancy had higher levels of parabens detected in urine ... Parabens are often used in beauty products because they have antimicrobial properties and can also act as a preservative. These ... The chemicals can cross through the skin and seep into the body, and some previous research also suggests that parabens in ...
Parabens are a group of chemical compounds widely used as preservatives in cosmetics, foods, and medicines. Health concerns ... What I think is funny is that you talk about eliminating parabens, but without a doubt many paraben-free products are using a ... They start with Propyl, Butyl, Methyl, Ethyl and Iso and always end in paraben. This issue with parabens is this --- they are ... Typically, the concentration of parabens in cosmetics is very low, often less than 1%. A mixture of parabens may be used to ...
Well, parabens are the bisphenol-A of the beauty industry, from the scary headlines to the happy proclamations that beam at you ... But as we mentioned before, parabens arent the only nasty no-no to avoid. Here are seven other toxic ingredients that ...
... "methyl paraben and ethyl paraben are not subjects of concern," but that "the safety assessment of propyl and butyl paraben ... Are parabens dangerous?. A 2004 study by Dr. Philippa Darbre published in the Journal of Applied Toxicology found parabens in ... What are parabens?. Parabens are the most widely used preservatives in cosmetics and personal care products such as soap, ... Paraben-free: Should you care?. We offer a primer on parabens: what they are, what health and safety professionals say about ...
URXBUP - Butyl paraben (ng/ml). Variable Name: URXBUP. SAS Label: Butyl paraben (ng/ml). English Text: Butyl paraben (ng/ml). ... URXEPB - Ethyl paraben (ng/ml). Variable Name: URXEPB. SAS Label: Ethyl paraben (ng/ml). English Text: Ethyl paraben (ng/ml). ... URXMPB - Methyl paraben (ng/ml). Variable Name: URXMPB. SAS Label: Methyl paraben (ng/ml). English Text: Methyl paraben (ng/ml) ... URXPPB - Propyl paraben (ng/ml). Variable Name: URXPPB. SAS Label: Propyl paraben (ng/ml). English Text: Propyl paraben (ng/ml) ...
... what are parabens? Were explaining what parabens are, if theyre safe in cosmetics and makeup, and sharing our best paraben ... WHAT ARE PARABENS?. Youve heard the word paraben, but were guessing you dont know exactly what parabens are. According to ... OUR BEST PARABEN FREE SHAMPOO AND CONDITIONER. Not only is this shampoo and conditioner duo paraben-free, but its also free of ... OUR BEST PARABEN FREE SKIN CARE PRODUCTS. Want to go paraben-free in your skin care routine, too? No problem-behold, our best ...
One group has examined how pets could be exposed to parabens, as reported in ACS journal Environmental Science & Technology. ... The paraben called methyl paraben and the metabolite called 4-hydroxybenzoic acid (4-HB) were the most abundant chemicals ... Parabens are preservatives commonly found in cosmetic and pharmaceutical products, and their use in human food products and dog ... One group has examined how pets could be exposed to parabens, as reported in ACS journal Environmental Science & Technology. ...
Found in everything from deodorant to food, some claim paraben is dangerous because... ... A person who wants to avoid paraben should look for "paraben-free" on product labels. He should also carefully check product ... and it remains to be seen whether the link between paraben and cancer will be proven. Still, it is a fact that paraben can ... Paraben is a type of chemical that can be found in different forms as a preservative; it is included in a wide variety of ...
Discover paraben free soap at World Market, and thousands more unique finds from around the world. Free Shipping on qualifying ...
A new study has found that chemicals called parabens can spur the growth of certain types of breast cancer cells. And they ... Q: Are parabens harmful?. Scientists are working hard to understand this. Parabens have a chemical structure thats similar to ... CDC: Biomonitoring Summary, Parabens. FDA: "Parabens.". ©2015 WebMD, LLC. All Rights Reserved. ... Q: Are the levels of parabens tested in the study like the levels were exposed to in real life? ...
7 Abstracts with Parabens-Associated Toxicity Research. Filter by Study Type. Animal Study. ... Ginger extract ameliorates paraben induced biochemical changes in liver and kidney of mice.May 01, 2007. ... Ginger significantly reduces paraben induced lipid peroxidation in liver and kidney cells. Jan 01, 2007. ... Neonates might be exposed to multiple sources of BPA and parabens in neonatal intensive care units.Oct 31, 2019. ...
... it might be worth it to look into the latest information about some of the ingredients.You have probably heard about parabens. ... What are parabens?. Parabens are preservatives used in many products including cosmetics, shampoos and conditioners, deodorants ... 1 source for finding paraben-free products. Sephora not only has entire paraben-free lines, but it also has developed a safety ... Where to get Moisturizers without Parabens. In the search for summer moisturizers, we found some great options that are paraben ...
If pregnant women use cosmetics containing parabens that remain on the skin for protracted periods, this may have consequences ... Parabens are used as preservatives in cosmetics. If pregnant women use cosmetics containing parabens that remain on the skin ... And high concentrations of parabens in the mothers urine were indeed associated with the use of cosmetics containing parabens ... Therefore, parabens seem to constitute as a risk factor during pregnancy for the occurrence of overweight. However, also other ...
The plant based paraben gives a shelf life of about 4-6 months.. Chemically produced paraben can give a shelf life of 4-10 ... At this point it is probably a good idea to reprise the paraben controversy. The fuss started when a study linked parabens in ... a paraben and, if so, whether this is potentially harmful.. The first question - is it a paraben - is fairly straight forward. ... Nonetheless, parabens have been found to accumulate in breast cancer tissue. Because PHBA is so similar, it acts in the same ...
It does not prove that parabens caused these cancers, and it does not suggest that parabens have any association with breast ... The researchers detected one or more parabens in 99% of tissue samples (158 of 160 analysed) and all five parabens in 60% of ... the fact that parabens are present in breast tissue samples taken from women with breast cancer does not mean that parabens ... the study cannot suggest that parabens have any association with breast cancer development at all. That parabens are present in ...
... s largest selection and best deals for Paraben-Free Black Travel Size Eye Make-Up. Shop with confidence on eBay! ...
Free Shipping on many items across the worlds largest range of Cream Paraben-Free Lip Makeup Palettes. Find the perfect ... ISH Lip Statement Palette FabFitFun 12 Colors Paraben Cruelty Free. Paraben free. Gluten free. Pucker up, ladies. Enriched with ... ISH Lip Statement Palette NEW FabFitFun Spring 2018 Paraben Free Cruelty Free. Mix any shades to create infinite combinations ...
Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitization.. Savage JH1, Matsui EC, Wood ... However, levels of the antimicrobial EDCs triclosan and parabens were significantly associated with allergic sensitization. The ... Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitization ... and ethyl parabens; and specific IgE levels were available for 860 children. Aeroallergen and food sensitizations were defined ...
... has today announced the addition of new line of Paraben free skin care products. Arthur Kalandarov said we will add the ... DeadSeaMineral.com (www.deadseamineral.com) has today announced the addition of new line of Paraben free skin care products. ... 17th September 2008) - - DeadSeaMineral.com (www.deadseamineral.com) has today announced the addition of new line of Paraben ... We hope to build on that success over the coming years with our new largely paraben free product lines. ...
  • Parabens are man-made chemicals often used in small amounts as preservatives in cosmetics, pharmaceuticals, foods, and beverages. (cdc.gov)
  • Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. (wikipedia.org)
  • Parabens are effective preservatives in many types of formulas. (wikipedia.org)
  • This is an article about parabens, a group of chemicals used in cosmetics as preservatives. (rsc.org)
  • Parabens are preservatives used in a wide variety of personal care products and foods to prevent the growth of microbes. (safecosmetics.org)
  • Parabens are a group of chemical compounds which are widely used as preservatives, especially in cosmetics. (wisegeek.com)
  • You can switch to solid shampoos and conditioners that need no preservatives, which is great, and then use a small amount of parabens if needed, or you can use mystery preservatives. (wisegeek.com)
  • Parabens are the most widely used preservatives in cosmetics and personal care products such as soap, moisturizers, shaving cream and underarm deodorant, according to the Food and Drug Administration. (latimes.com)
  • Sometimes cosmetic companies might jump on the paraben-free bandwagon without really doing a proper assessment of … the safer preservatives that they ought to be adding. (latimes.com)
  • Parabens are short alkyl chain esters of para-hydroxybenzoic acid (PHBA) that are widely used as preservatives in pharmaceuticals, cosmetics and in such personal care products as shampoos, hair and shaving products, facial and skin cleansers, and lotions. (cdc.gov)
  • According to the Centers for Disease Control and Prevention (CDC), parabens are man-made chemicals that are often used as preservatives in all sorts of products, including cosmetics and also foods and beverages. (lorealparisusa.com)
  • Parabens are used as preservatives in order to help prevent the growth of harmful bacteria and mold within a product's formula, per the Food & Drug Administration . (lorealparisusa.com)
  • According to research published by the National Institutes of Health , parabens have been used as preservatives in the cosmetics, food, and pharmaceutical industries for decades-more than 70 years, to be exact. (lorealparisusa.com)
  • From an allergy standpoint, research claims that parabens remain one of the least allergenic preservatives available. (lorealparisusa.com)
  • Parabens are preservatives commonly found in cosmetic and pharmaceutical products, and their use in human food products and dog and cat food is regulated by the U.S. Food & Drug Administration. (eurekalert.org)
  • Parabens are preservatives used in many products including cosmetics, shampoos and conditioners, deodorants and household cleaning products. (savannahnow.com)
  • Parabens are used as preservatives in cosmetics. (news-medical.net)
  • Methylparaben, propylparaben, butylparaben - these and similar are the names of parabens commonly used as preservatives. (news-medical.net)
  • Like a growing number of beauty companies, Jane Iredale is searching for preservatives that are not chemicals, or parabens, and are as safe as possible. (truthinaging.com)
  • The researchers explained that five parabens (n-propylparaben, methylparaben, n-butylparaben, ethylparaben and isobutylparaben) are widely used as preservatives in consumer products, in the pharmaceutical and cosmetic industry, despite the possibility that they are slightly toxic. (www.nhs.uk)
  • Parabens were so popular because of their gentle, non-sensitizing, and highly effective profile in comparison to other preservatives but also because they were derived naturally from plants, a rare phenomenon for a preservative. (paulaschoice.com)
  • There are studies indicating absorption of parabens through skin associated with application of skincare products, but those studies did not take into consideration that parabens are still used as food-grade preservatives or that they are found naturally in plants, so either source could have been the origin, not the cosmetics. (paulaschoice.com)
  • The alkyl esters of p-hydroxybenzoic acid (parabens), which are used as preservatives in consumer products, possess oestrogenic activity and have been measured in human breast tissue. (greenmedinfo.com)
  • Paraben Preservatives Aren't as Toxic as Consumers Think. (gcimagazine.com)
  • Natural preservatives, like benzyl alcohol, are a great alternative to paraben, and boast the same benefits. (superdrug.com)
  • Parabens are synthetic preservatives that help your skincare and makeup fresher for longer. (skinstore.com)
  • Any product that contains traces of water is susceptible to bacteria, but preservatives ward them off and parabens are the most effective. (skinstore.com)
  • You may have heard of these sneaky little preservatives called parabens. (100percentpure.com)
  • Parabens are chemicals that have been used since the 1950s as preservatives to prevent the growth of bacteria in cosmetics, shampoos, lotions, and even lubricants. (fairhavenhealth.com)
  • Parabens are one of the most widely used preservatives in personal care products, but many health concerns have cropped up over the years. (truthinaging.com)
  • Parabens are naturally-occurring preservatives that are used to protect against a wide range of bacteria and fungi. (truthinaging.com)
  • While paraben preservatives are typically a very small percentage of a personal lubricants formula they are very potent. (holisticwisdom.com)
  • Parabens are used as inexpensive preservatives acting as antimicrobials. (grist.org)
  • Parabens and their salts are also valued by cosmetic and skin care product manufacturers as preservatives because they have effective fungicidal and bacterial properties, and are also fairly inexpensive. (hubpages.com)
  • Parabens are preservatives used in many foods, medicines and most commonly in cosmetic products and underarm deodorants and antiperspirants. (beautynewsnyc.com)
  • Parabens are artificial preservatives used in many domestic manufacturing industries especially for cosmetics, food and drugs industries. (vitanetonline.com)
  • By using sophisticated analytical chemistry techniques and performing complex biological tests to quantify hormonal activity, the Granada-based researchers studied the presence of the plastic component bisphenol A, the preservatives known as parabens, and the hormonal activity (estrogenicity and androgenicity) of the sock extracts. (ugr.es)
  • Parabens are preservatives that are synthetic, and are often used as fillers in beauty and skin care products. (trustedhealthproducts.com)
  • Parabens are commonly used as preservatives in cosmetic products - especially in creams and body lotions in order to protect against microbial growth. (cosmeticsdesign-europe.com)
  • Parabens (or their salts) are widely used as preservatives in cosmetics, toiletries, and pharmaceuticals due to their relatively low toxicity profile and a long history of safe use. (nih.gov)
  • Parabens are a class of chemicals commonly used as preservatives in cosmetics and personal care products. (kitchenstewardship.com)
  • Parabens are effective preservatives widely used in cosmetic products and processed food, with high human exposure. (mdpi.com)
  • The most commonly used parabens are methylparaben, propylparaben, and butylparaben, according to the FDA. (webmd.com)
  • Common parabens include methylparaben (E number E218), ethylparaben (E214), propylparaben (E216), butylparaben and heptylparaben (E209). (wikipedia.org)
  • Since it can be concluded that the estrogenic activity of butylparaben is negligible under normal use, the same should be concluded for shorter analogs due to estrogenic activity of parabens increasing with the length of the alkyl group. (wikipedia.org)
  • The so-called "long chain" parabens [14] (butylparaben and its alternative form, isobutylparaben and isopropylparaben and propylparaben) have the strongest estrogenic activity among those widely used in personal care products. (safecosmetics.org)
  • Our results provide strong evidence that parabens, in particular butylparaben, contribute to an increased risk that children will become overweight," said senior study author Tobias Polte of Leipzig University Medical Center in Germany. (medscape.com)
  • Another reason that parabens have been in the spotlight (often in a negative light) is because these chemicals, which include methylparaben, propylparaben, and butylparaben, also have weak estrogenic effects within the body, according to Harvard Medical School . (lorealparisusa.com)
  • Its molecular structure is similar to parabens (methyparaben, ethylparaben, propylparaben or butylparaben). (truthinaging.com)
  • There are now many safer options that didn't exist 10 years ago so always check your labels for ingredients listed as butylparaben, isobutylparaben, isopropylparaben, methylparaben and propylparaben or look for the term 'paraben-free. (alternativesjournal.ca)
  • Commonly used parabens include methylparaben, ethylparaben, propylparaben and butylparaben. (holisticwisdom.com)
  • Denmark s environmental ministry announced on 12-20-10 that it is banning two types of parabens: propylparaben and butylparaben in lotions and other cosmetic products for children under three years of age. (holisticwisdom.com)
  • The most common parabens used in cosmetics are methylparaben , propylparaben and butylparaben . (beautynewsnyc.com)
  • The most common type of Parabens are methyl, propyl and butylParaben. (vitanetonline.com)
  • Parabens are antimicrobials that protect cosmetics and other products from contamination and help to extend shelf life. (yahoo.com)
  • In 2006, the industry-led Cosmetic Ingredient Review (CIR), in a partnership with the U.S. Food and Drug Administration (FDA), determined that there was no need to change CIR's original conclusion from 1984 that parabens are safe for use in cosmetics. (cdc.gov)
  • FDA states that they have no information that use of parabens in cosmetics has any effect on health. (wikipedia.org)
  • Propyl paraben is starting to disappear from some cosmetics, so it is a wonder that it is still allowed in food. (ewg.org)
  • Cosmetics companies are taking the hint and have started removing propyl paraben from some of their products. (ewg.org)
  • This article is about parabens, chemicals that are used cosmetics that have been linked to breast cancer and are suspected endocrine disruptors. (rsc.org)
  • The significance of this finding cannot be underestimated because girls and women typically used more personal care products and cosmetics containing parabens than do boys and men," Claudio said. (medscape.com)
  • In addition to being used in cosmetics, parabens are also utilized by the pharmaceutical industry, and they sometimes appear as food additives as well. (wisegeek.com)
  • People who are concerned about parabens argue that their estrogenic traits make them too dangerous to use in food, cosmetics, and pharmaceuticals. (wisegeek.com)
  • This issue with parabens is this --- they are in 98% of cosmetics and skincare products and the average women uses 12 products EVERYDAY that have parabens. (wisegeek.com)
  • The "FDA believes that at the present time there is no reason for consumers to be concerned about the use of cosmetics containing parabens," the post says. (latimes.com)
  • Instead of parabens, Josie Maran Cosmetics uses ingredients such as ethylhexylglycerin, which is plant-derived. (latimes.com)
  • Additionally, we are constantly using our hands to touch, use, and apply cosmetics and, as gross as it sounds, the microorganisms on your hands can contaminate a product over time-which is another reason manufacturers add parabens to their product formulas. (lorealparisusa.com)
  • If pregnant women use cosmetics containing parabens that remain on the skin for protracted periods, this may have consequences for their child's subsequent weight development. (news-medical.net)
  • Using the ToxFox app developed by BUND enabled us to easily and quickly check whether parabens were among the ingredients of the respective cosmetics products', Polte explains. (news-medical.net)
  • And high concentrations of parabens in the mothers' urine were indeed associated with the use of cosmetics containing parabens - particularly those that remained on the skin for a protracted period of time, such as creams or body lotions. (news-medical.net)
  • Over the past 10 years parabens have become criticized and condemned for use in cosmetics due to their alleged relation to health concerns affecting women and men. (paulaschoice.com)
  • However, these studies don't apply to the tiny amount (1% or less) of parabens typically used in cosmetics. (paulaschoice.com)
  • Teen girls may be at particular risk to chemicals such as parabens and triclosan used in cosmetics and personal care formulations, a study finds. (cosmeticsandtoiletries.com)
  • While we believe that parabens are safely used in cosmetics, we do understand there are times when a paraben free choice is appreciated. (thesage.com)
  • Most parabens used in cosmetics tend to be chemically synthesized. (truthinaging.com)
  • But in fact, the parabens could have been naturally produced by the subjects' own bodies, found in food or in the environment - and to a much smaller extent, absorbed by skin care and cosmetics. (truthinaging.com)
  • Because they can also be found in cosmetics, women are typically at a higher risk for having high levels of Parabens found in their blood. (holisticwisdom.com)
  • Parabens have been used in beauty products for over fifty years, have been thoroughly researched, and have been regarded as a reasonably safe ingredient to add to skin care products and cosmetics. (hubpages.com)
  • According to Ellen Burov M.D. , a dermatologist in New York City, parabens in cosmetics are safe. (beautynewsnyc.com)
  • Cosmetics that may contain parabens include shaving products, hair care products, lotions, moisturizers and makeup. (beautynewsnyc.com)
  • For a list of paraben-free cosmetics, visit www.thinkbeforeyoupink.org . (beautynewsnyc.com)
  • Although cosmetics aims at enhancing your beauty by making you look young, use of Parabens can actually hastens skin aging process. (vitanetonline.com)
  • You'd think that getting rid of parabens would make cosmetics safer. (beautifulwithbrains.com)
  • The danger of parabens (in cosmetics, skincare products, baby wash) and how they are absorbed. (hubpages.com)
  • Whether or not the claims about the dangers of parabens are true, cosmetics companies have compensated for the backlash and now offer a wide variety of paraben-free products. (howstuffworks.com)
  • While the researchers have not, so far, been able to come to firm conclusions on how stable these epigenetic modifications are - or whether they can be passed on to the next generation - they do warn that use of cosmetics containing parabens during pregnancy is a risk and that the 'unambiguous' recommendation should be to not use such products during pregnancy. (cosmeticsdesign-europe.com)
  • He noted that many cosmetics products already declare to be paraben-free, but added that where there is any concern information can be obtained from the list of ingredients or using the ToxFox app, for instance. (cosmeticsdesign-europe.com)
  • Propyl paraben is a widely used preservative in pharmaceuticals, cosmetics, and foods preventing microbial and fungal contamination. (rsc.org)
  • The FDA and most of the cosmetics industry insist that parabens are safe in personal care products. (kitchenstewardship.com)
  • CDC scientists found Methylparaben and propylparaben in the urine of most of the people tested, indicating widespread exposure to these parabens in the U.S. population. (cdc.gov)
  • Females had several-fold higher concentrations of methylparaben and propylparabens than males, which likely reflect the greater use of products containing parabens. (cdc.gov)
  • Applying personal care product containing parabens-especially methylparaben-can lead to UV-induced damage of skin cells and disruption of cell proliferation (cell growth rate). (safecosmetics.org)
  • Methylparaben, for example, is regarded as more potent than PHBA but both are regarded as hormone disruptors, as one study concluded: "It can be concluded that removal of the ester group from parabens does not abrogate its oestrogenic activity and that p-hydroxybenzoic acid can give oestrogenic responses in human breast cancer cells. (truthinaging.com)
  • Paraben has been known to increase the skin's sensitivity to UV rays (especially methylparaben), so look out for paraben-free products that will give you peace of mind when catching those rays. (superdrug.com)
  • Parabens were found in all the products studied-in particular ethylparaben, followed by methylparaben-but in average concentrations lower than those of bisphenol A and with less pronounced differences between store type. (ugr.es)
  • Methylparaben, also methyl paraben, one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO). (wikipedia.org)
  • A 2008 study found no competitive binding for human estrogen and androgen receptors for methylparaben, but varying levels of competitive binding were seen with butyl- and isobutyl-paraben. (wikipedia.org)
  • The pastry you're thinking about buying may contain the preservative propyl paraben, linked to disruptions in hormone signaling. (ewg.org)
  • Parabens are often used in beauty products because they have antimicrobial properties and can also act as a preservative. (medscape.com)
  • A mixture of parabens may be used to create the best preservative effect, ensuring that molds, fungi, bacteria, and other unwanted visitors will not contaminate a product. (wisegeek.com)
  • You might want to look closely at the 'paraben-free'-labeled products if they haven't replaced it with a more allergenic preservative. (wisegeek.com)
  • What I think is funny is that you talk about eliminating parabens, but without a doubt many paraben-free products are using a preservative that has just come out within the last year -- a preservative that has little testing and no long term testing. (wisegeek.com)
  • Parabens are most widely tested preservative, so you can make the choice. (wisegeek.com)
  • But even though she says that parabens may disrupt hormones or mimic estrogen (which is thought to promote breast cancer in some women), "You certainly don't want parabens to be pulled out and a more dangerous preservative to be put in," such as one that releases formaldehyde. (latimes.com)
  • And so a heated debate has been going on about whether the honeysuckle preservative (marketed under the name of Plantservative) is, indeed, a paraben and, if so, whether this is potentially harmful. (truthinaging.com)
  • I'm not going to give up all products with the honeysuckle extract preservative, but I will now be aware that they contain a paraben-like substance and extend the same caution to them. (truthinaging.com)
  • Paraben is a common antimicrobial preservative used to stop nasty bacteria from infecting our everyday products. (superdrug.com)
  • One of the most widely used chemicals suspected of endocrine disruption is the cosmetic preservative known as the paraben. (alternativesjournal.ca)
  • Parabens are known toxins that can contribute to a slew of health problems and are used as a germicide and preservative as they are cheap and effective. (holisticwisdom.com)
  • Parabens, which are a type of preservative found in everything from shampoo, conditioner and deodorants to moisturisers and sunscreen have been the subject of multiple investigations over the years. (mindfood.com)
  • If a product doesn't contain parabens, companies will usually mark it "paraben-free," a designation that's more and more common since the 2004 study raised public awareness. (yahoo.com)
  • People can be exposed to parabens through touching, swallowing, or eating products that contain parabens. (cdc.gov)
  • Mothers who reported using products known to contain parabens during pregnancy had higher levels of parabens detected in urine tests than women who said they didn't use these products while they were pregnant, the study found. (medscape.com)
  • How to know if your skin care products contain parabens and what to do. (100percentpure.com)
  • Brand names such as K-Y Jelly, Astroglide, Wet, I-D, System JO, Shunga and even party plan lines such as Passion Parties Romanta Therapy line are just a few of the lubricants that have been known to contain Parabens. (holisticwisdom.com)
  • Most natural products do not contain parabens. (beautynewsnyc.com)
  • Most major brands, deodorants, and antiperspirants do not currently contain parabens. (beautynewsnyc.com)
  • Human health effects from environmental exposure to low levels of parabens are unknown. (cdc.gov)
  • Biomonitoring studies on levels of parabens provide physicians and public health officials with reference values so that they can determine whether people have been exposed to higher levels of parabens than are found in the general population. (cdc.gov)
  • Q: Are the levels of parabens tested in the study like the levels we're exposed to in real life? (webmd.com)
  • The researchers found that dry food contained higher levels of parabens and their metabolites than wet food. (eurekalert.org)
  • It was also noted that the levels of parabens were found to be significantly higher in the region closest to the armpits, making underarm products with parabens highly suspect. (alternativesjournal.ca)
  • While the Cosmetic Ingredient Review [link to regulation section] recommends concentration limits for single (up to 0.4%) and total paraben concentrations (up to 0.8%) in a single product, these recommendations do not account for exposure to parabens from several products by a single individual. (safecosmetics.org)
  • [10] Studies demonstrate that at sufficient concentrations, parabens can increase cell proliferation in human breast cancer MCF-7 cells, which are often used as a sensitive measure of estrogenic activity. (safecosmetics.org)
  • Concentrations of parabens in other products, like foods and pharmaceuticals, are similarly quite low. (wisegeek.com)
  • In addition, the researchers report, cat food had higher paraben concentrations than dog food. (eurekalert.org)
  • Based on data collected for that study, Rudel says people who get exposed to the highest levels in the U.S. have paraben concentrations in their bodies that are about at the levels used in the new study. (emedicinehealth.com)
  • Urinary concentrations of four parabens in the U.S. population: NHANES 2005-2006. (greenmedinfo.com)
  • They also found differences in the concentrations of individual parabens and where they were predominantly located in the breast. (www.nhs.uk)
  • They observed that the concentrations of parabens varied between women. (www.nhs.uk)
  • Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells. (greenmedinfo.com)
  • In this paper, we have investigated the extent to which proliferation of MCF-7 human breast cancer cells can be increased by exposure to the five parabens either alone or in combination at concentrations as recently measured in 160 human breast tissue samples. (greenmedinfo.com)
  • Proliferation of MCF-7 cells could be increased by combining all five parabens at concentrations down to the 50(th) percentile (median) values measured in the tissues. (greenmedinfo.com)
  • This demonstrates that parabens, either alone or in combination, are present in human breast tissue at concentrations sufficient to stimulate the proliferation of MCF-7 cells in vitro, and that functional consequences of the presence of paraben in human breast tissue should be assessed on the basis of all five parabens and not single parabens individually. (greenmedinfo.com)
  • Concentrations of methyl and propyl parabens decreased by 43.9% and 45.4%, respectively. (cosmeticsandtoiletries.com)
  • Unexpectedly, paraben concentrations of ethyl and butyl paraben in particular increased, although concentrations were low overall and not detected in almost half the samples, the study found. (cosmeticsandtoiletries.com)
  • Breast cancer tumors contained measurable amounts of six parabens, found in relative concentrations that closely parallel their use in the synthesis of cosmetic products. (100percentpure.com)
  • However, regarding the very rapid metabolism of these compounds to the inactive p -hydroxybenzoic acid by esterases, it needs to be determined under which conditions low micromolar concentrations of these parabens or their mixtures can occur in target cells to effectively disturb estrogen effects in vivo. (mdpi.com)
  • According to Randy Schueller, a cosmetic chemist and the founder of The Beauty Brains , this notion stems from a 2004 study that showed parabens were present in human breast tumors. (yahoo.com)
  • The new study found that in the presence of growth-promoting substances that are normally in breast tissue, parabens can promote the growth of estrogen-sensitive breast tumors even in tiny amounts -- around 5 to 10 nanograms. (webmd.com)
  • A 2004 UK study detected traces of five parabens in the breast tumors of 19 out of 20 women studied. (safecosmetics.org)
  • [7] This is the region in which the highest proportion of breast tumors is found, although paraben concentration in the tissue samples was not related to location of breast tumors in individual women. (safecosmetics.org)
  • A 2004 study by Dr. Philippa Darbre published in the Journal of Applied Toxicology found parabens in breast tumors. (latimes.com)
  • Two studies have found parabens in human breast tumors. (emedicinehealth.com)
  • In part of her investigation of estrogen's effects on breast cancer, her team identified parabens in 18 of 20 biopsies of breast cancer tumors. (100percentpure.com)
  • Research has proven that Parabens were found in biopsies from breast tumors. (holisticwisdom.com)
  • In 2004 there was a study done in the UK that detected five types of Parabens in the breast cancer tumors of 19 out of the 20 women studied. (holisticwisdom.com)
  • However, it does demonstrate that there was a presence of Parabens that were intact in the cancerous tumors. (holisticwisdom.com)
  • The study] detected parabens in breast tumors. (grist.org)
  • Parabens are found in breast tumors, and several other forms of cancerous tumors. (hubpages.com)
  • The fact that parabens have been found in breast cancer tumors is a dirty secret in the beauty industry. (kitchenstewardship.com)
  • However, since many types of parabens in many types of products are used commonly, further assessment of the additive and cumulative risk of multiple paraben exposure from daily use of multiple cosmetic and/or personal care products is needed. (wikipedia.org)
  • There are several types of parabens. (wisegeek.com)
  • Oftentimes, one product will contain multiple different types of parabens. (lorealparisusa.com)
  • Allergic reactions to it are relatively rare when you consider how common it is, but different types of parabens also often appear in the same product, increasing the chance of a reaction. (howstuffworks.com)
  • Exposure to phenols, phthalates, and parabens and development of metabolic syndrome among Mexican women in midlife. (greenmedinfo.com)
  • Adolescent girls who use personal care products that are labeled to be "free of" phthalates, parabens , triclosan , and benzophenone -3 ( BP-3), can reduce personal exposure to possible endocrine disrupting chemicals, a recent study has found. (cosmeticsandtoiletries.com)
  • This study demonstrates that techniques available to consumers, such as choosing personal care products that are labeled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal exposure to possible endocrine disrupting chemicals. (cosmeticsandtoiletries.com)
  • On 5-3-11 a ban was put into effect for phthalates, alkylphenols and parabens in consumer and professional products by the French National Assembly. (holisticwisdom.com)
  • Free of parabens, phthalates, SLS and artificial fragrances, NEW Kiss My Face Kids Defense™ Air Powered Spray™ SPF 50, Kids Defense™ Mineral SPF 30 and Cool Sport Any Angle Air Powered Spray™ SPF 50 contain Antioxidant Defenders™ to protect against harmful UV rays and they spray just as big a surface and as easily as any mainstream aerosol/ air powered bottle! (girliegirlarmy.com)
  • Unfortunately, deciding whether or not it's necessary to avoid parabens can be difficult, as some studies assert they are not dangerous, while others claim they are not safe. (wisegeek.com)
  • Marta, you are known to avoid parabens in skin care. (truthinaging.com)
  • A good way to avoid parabens and other questionable chemicals is by reading the ingredients label or looking products up on the Environmental Working Group's Skin Deep Database or on the Good Guide . (grist.org)
  • It's impossible to avoid parabens. (beautynewsnyc.com)
  • The FDA acknowledges the known weak endocrine disrupting properties of parabens, but state s , "They have been shown to have much less estrogenic activity than the body's naturally occurring estrogen. (yahoo.com)
  • Parabens have a chemical structure that's similar to estrogen, and they can mimic this hormone's activity in the body. (webmd.com)
  • A 2005 review concluded "it is biologically implausible that parabens could increase the risk of any estrogen-mediated endpoint, including effects on the male reproductive tract or breast cancer" and that "worst-case daily exposure to parabens would present substantially less risk relative to exposure to naturally occurring endocrine active chemicals in the diet such as the phytoestrogen daidzein. (wikipedia.org)
  • Parabens are potential endocrine disruptors due to their ability to mimic estrogen. (safecosmetics.org)
  • [9] In cell studies, parabens have been found to weakly bind to estrogen receptors. (safecosmetics.org)
  • [16] In addition to direct estrogenic effects, parabens can block androgens (for example, testosterone) [17] and inhibit enzymes that metabolize estrogen. (safecosmetics.org)
  • Health concerns about parabens are primarily focused on their potential to act like estrogen compounds in the body. (wisegeek.com)
  • The cumulative impact of parabens on a womens estrogen levels and long-term health are serious. (wisegeek.com)
  • One issue some experts raise is that parabens may actually act like estrogen in the body. (wisegeek.com)
  • Some parabens have been detected in breast tissue and one concern is that they are linked to estrogen-triggered breast cancers. (savannahnow.com)
  • Because parabens mimic human estrogen and it is known that estrogen stimulates cancer, the link seemed plausible. (truthinaging.com)
  • The author, Emily Harari, a scientist in genetics at UC Berkeley, succinctly explains how the 1998 study showed parabens could weakly mimic the body's estrogen hormone, and since increased estrogen is associated with breast cancer, fear of parabens spread without the average consumer considering these effects could be negligible. (gcimagazine.com)
  • Known to be endocrine disrupters, parabens are sneaky in that they can mimic the activity of the hormone estrogen in the body's cells. (fairhavenhealth.com)
  • Parabens mimic estrogen by binding to estrogen receptors on cells. (holisticwisdom.com)
  • Parabens are known to mimic estrogen when introduced into the body and are thus considered endocrine disruptors. (holisticwisdom.com)
  • Parabens act as hormone or endocrine disruptors, meaning they mimic estrogen in the body - which can lead to health problems. (grist.org)
  • The study also discussed this information in the context of the weak estrogen-like properties of parabens and the influence of estrogen on breast cancer. (grist.org)
  • There isn't any scientific evidence that proves that parabens are cancerous but findings have shown parabens to act like weak estrogen-like properties. (beautynewsnyc.com)
  • When absorbed into the body system, Parabens disrupts endocrine system by increasing production of hormone notably estrogen and at times they may act as estrogen. (vitanetonline.com)
  • The most notable effect of increased estrogen in the body resulting from use of Parabens is breast cancer. (vitanetonline.com)
  • One of the ways that parabens are dangerous is that they have the capacity to mimic the hormone estrogen. (trustedhealthproducts.com)
  • Girls and boys alike can be negatively impacted by the estrogen mimicry that parabens so often cause. (trustedhealthproducts.com)
  • Testing of parabens has revealed to varying degrees that individual paraben compounds have weakly estrogenic activity in some in vitro screening tests, such as ligand binding to the estrogen receptor, regulation of CAT gene expression, and proliferation of MCF-7 cells. (nih.gov)
  • However, in relation to estrogen as a control during in vivo studies, the parabens with activity are many orders of magnitude less active than estrogen. (nih.gov)
  • In this review, a comparative approach involving both dose and potency is used to assess whether in utero or adult exposure to parabens might be associated with adverse effects mediated via an estrogen-modulating mode of action. (nih.gov)
  • Based on these comparisons using worst-case assumptions pertaining to total daily exposures to parabens and dose/potency comparisons with both human and animal no-observed-effect levels (NOELs) and lowest-observed-effect levels (LOELs) for estrogen or DES, it is biologically implausible that parabens could increase the risk of any estrogen-mediated endpoint, including effects on the male reproductive tract or breast cancer. (nih.gov)
  • Additional analysis based on the concept of a hygiene-based margin of safety (HBMOS), a comparative approach for assessing the estrogen activities of weakly active EACs, demonstrates that worst-case daily exposure to parabens would present substantially less risk relative to exposure to naturally occurring EACs in the diet such as the phytoestrogen daidzein. (nih.gov)
  • Specifically, parabens mimic the hormone estrogen, potentially disrupting hormone function, which can lead to reproductive issues as well as cancers and even immune and neurological disorders. (kitchenstewardship.com)
  • This work investigated the potential interference of parabens with the estrogen-activating enzyme 17β-hydroxysteroid dehydrogenase (17β-HSD) 1 and the estrogen-inactivating 17β-HSD2. (mdpi.com)
  • Parabens have been a topic of some controversy, due to consumer concerns about their safety, which explains why you may find products voluntarily labeled as " paraben free," using their ingredients as a selling point for concerned consumers. (wisegeek.com)
  • Target's Web site is not easy to search like the previous two for paraben-free and does not always list the ingredients. (savannahnow.com)
  • With ingredients formulated to hydrate dry hair from root to tip and free of parabens and harmful ingredients, our moisturizing shampoo is the perfect hair care product for daily use. (livingproof.com)
  • Free of parabens and harmful ingredients, our moisturizing shampoo is the perfect product for daily use. (livingproof.com)
  • Another study published by Toxicology and Applied Pharmacology showed that parabens had weak estrogenic activity in the body and suggested that the safety of these ingredients needed to be reassessed. (alternativesjournal.ca)
  • Typically, natural and organic products that are Paraben Free and use more natural antibacterial ingredients only last six months to one year and should be disposed of after that time to avoid exposure to bacteria growth. (holisticwisdom.com)
  • You can tell if a product contains parabens by reading the ingredients label. (grist.org)
  • Parabens is a family of ingredients based on parahydroxybenzoic acid. (beautifulwithbrains.com)
  • Fondly regarded as 'the comfort food of skin care' by Repêchage Vice President Shiri Sarfati, the range features the finest natural, paraben-free ingredients from juicy mango and papaya to nourishing coconut and shea butter as well as a range of teas, living up to Kanshi's African translation of "aromatic" or "beautifully scented," providing a head to aromatic toe beauty experience. (massagemag.com)
  • Not only is this shampoo and conditioner duo paraben-free, but it's also free of sulfates. (lorealparisusa.com)
  • Parabens are a chemical substance used in everyday personal care items like body wash, lotion, shampoo, conditioner, moisturizer, baby wash, hand soap and pretty much any other product that you can pick up in the personal care aisle. (hubpages.com)
  • Free from parabens and dyes and formulated with macadamia oil, wheat proteins and avocado - this shampoo and conditioner gently cleanses while helping to recover soft, healthy-looking hair every time you lather up. (divine.ca)
  • Due to this hormonal activity, bisphenols and parabens are endocrine disruptors associated with certain dysfunctions that can lead to illnesses in both children and adults. (ugr.es)
  • Numerous studies have shown that parabens are endocrine disruptors, meaning they interfere with the normal action of hormones in the body. (kitchenstewardship.com)
  • Less common parabens include isobutylparaben, isopropylparaben, benzylparaben and their sodium salts. (wikipedia.org)
  • By measuring these chemicals in urine, scientists can estimate the amount of parabens that has entered people's bodies. (cdc.gov)
  • Finding a measurable amount of parabens in urine does not imply that they cause an adverse health effect. (cdc.gov)
  • Last year, a report published by the Journal of Applied Toxicology measured the amount of parabens in tissue samples from the mastectomies of 40 different breast cancer patients. (alternativesjournal.ca)
  • Parabens are known to contribute to excessive weight, though actual gain depends on individual and the amount of Parabens in the body, they interfere with thyroid glands which leads to excessive weight gain since body cannot regulate the amount of Parabens in the body. (vitanetonline.com)
  • Other studies have shown that parabens are weak endocrine disrupters, but there are still knowledge gaps, but a 2005 study estimated that the exposure level you get from personal care items is too low to pose any real risk. (yahoo.com)
  • Animal experiments have shown that parabens have weak estrogenic activity, acting as xenoestrogens. (wikipedia.org)
  • They said that some studies have shown that parabens have similar properties to oestrogen, which is known to play a role in the development and progression of breast cancer, and there has been speculation that there could be a link between parabens and cancer. (www.nhs.uk)
  • The study's scientists didn't test healthy tissue for the presence of parabens as a comparison, but the study results were still sufficient to prompt other scientists to look more closely. (yahoo.com)
  • The study was criticized for not demonstrating cause and effect, only the mere presence of parabens. (truthinaging.com)
  • They used laboratory methods to look at the concentration of parabens in each of these samples. (www.nhs.uk)
  • However, other research has concluded they are indeed problematic: Some studies determined a 100% concentration of parabens caused skin samples (meaning not intact skin on a person) to break down. (paulaschoice.com)
  • The researchers detected one or more parabens in 99% of tissue samples (158 of 160 analysed) and all five parabens in 60% of samples (96 of 160). (www.nhs.uk)
  • The American Cancer Society mentioned a 2004 study that found parabens in the breast tissue of mastectomy patients but did not find parabens to be a cause of the cancers. (wikipedia.org)
  • The odds of aeroallergen sensitization significantly increased with the level of the antimicrobial EDCs triclosan and propyl and butyl parabens (P ≤ .04). (nih.gov)
  • The general chemical structure of a paraben is shown at the top right of this page, where R symbolizes an alkyl group such as methyl, ethyl, propyl or butyl. (wikipedia.org)
  • According to the most recent studies [2011], cosmetic parabens have a clean bill of health. (yahoo.com)
  • Dr. Wilma Bergfeld, chairwoman of the Cosmetic Ingredient Review panel, an independent body established by the industry that shares findings with the FDA, says the panel is monitoring the scientific literature and will review the safety of parabens again as new studies become available. (latimes.com)
  • This, of course, aligns with the Cosmetic Ingredient Review's conclusion regarding parabens. (gcimagazine.com)
  • It should be said, that based on this small study regarding breast cancer, in the USA the Cosmetic Ingredient Review (CIR), the Food & Drug Administration (FDA) as well as the National Cancer Institute (NCI) have said that there is no conclusive evidence that Parabens cause cancer. (holisticwisdom.com)
  • Parabens are a common cosmetic ingredient and you may have recently come across some hair products claiming to be paraben-free. (divine.ca)
  • A ligand-based 17β-HSD2 pharmacophore model was applied to screen a cosmetic chemicals database, followed by in vitro testing of selected paraben compounds for inhibition of 17β-HSD1 and 17β-HSD2 activities. (mdpi.com)
  • citation needed] Most of the available paraben toxicity data are from single-exposure studies, meaning one type of paraben in one type of product. (wikipedia.org)
  • Parabens are used in personal lubricants to kill bacteria and do have toxicity to cells, which is cause for concern. (holisticwisdom.com)
  • Of greatest concern is that Parabens are known to disrupt hormone function, an effect that is linked to increased risk of breast cancer and reproductive toxicity. (holisticwisdom.com)
  • In collaboration with colleagues from the Medical Faculty at Leipzig University, the researchers used a mouse model to simulate exposure to parabens during pregnancy. (news-medical.net)
  • Additionally, exposure to parabens during pregnancy can result in male babies being born with genital abnormalities. (fairhavenhealth.com)
  • VitaSprings does not imply any medical claims from the customer reviews on this OH Warming Lubricant Paraben Free product on this website. (vitasprings.com)
  • Write a Review on this OH Warming Lubricant Paraben Free product and share your experience or opinion with other customers. (vitasprings.com)
  • Buy OH Warming Lubricant Paraben Free from Emerita at VitaSprings, and we guarantee you a safe, secure online shopping experience! (vitasprings.com)
  • The chemicals can cross through the skin and seep into the body, and some previous research also suggests that parabens in products used by pregnant women can impact their babies' development. (medscape.com)
  • Even so, it makes sense for pregnant women to check product labels and steer clear of beauty items containing parabens, said Luz Claudio, an environmental health researcher at the Icahn School of Medicine in New York City who wasn't involved in the study. (medscape.com)
  • If pregnant women absorb parabens through the skin, this can lead to overweight in their children', says UFZ environmental immunologist Dr Tobias Polte. (news-medical.net)
  • Indeed, the authors cite earlier research that found parabens in 100% of urine samples from children and pregnant women. (www.nhs.uk)
  • Studies have shown that of the pregnant women with parabens in their own blood, all have parabens in their umbilical cord blood samples as well. (fairhavenhealth.com)
  • Researchers have also reported that chemicals like parabens could be absorbed through the skin of pregnant women and then adversely affect the development of male foetuses in the womb. (hubpages.com)
  • But how does the use of creams containing parabens by expectant mothers tie in with the child's future overweight? (news-medical.net)
  • As you discovered, the drugstore often leaves much to be desired in finding paraben-free products - even first aid creams have parabens in them. (grist.org)
  • Parabens stop fungus, bacteria and other microbes from growing in your favourite creams, hair products and makeup especially in the moist, warm environment of a bathroom. (divine.ca)
  • Citing the study by the researchers in Tokyo, the European Food Safety Authority issued an advisory in 2004 that the presumed safe exposure level for propyl paraben in food was no longer valid because it affected sex hormones and the male reproductive organs in young rats (EFSA 2004). (ewg.org)
  • SUNY Downstate Medical Center's School of Public Health linked parabens to reproductive defects in newborns . (truthinaging.com)
  • Parabens have negative effects to reproductive health, for instance, they leads to low level of testosterone. (vitanetonline.com)
  • Within this ongoing birth cohort, certain phenols and parabens were associated with altered reproductive and thyroid hormone levels during pregnancy. (northeastern.edu)
  • Paraben exposure can also negatively affect the reproductive systems of men. (trustedhealthproducts.com)
  • Nonetheless, parabens have been found to accumulate in breast cancer tissue. (truthinaging.com)
  • However, the fact that they can accumulate in breast tissue prompts me to be cautious of exposing myself to parabens more than absolutely necessary. (truthinaging.com)
  • Research shows that Parabens accumulate in breast and are major contributors to breast cancer. (vitanetonline.com)
  • While no studies have directly linked exposure to parabens to breast cancer, we do know that parabens can be absorbed through the skin and can persist and accumulate in breast tissue. (kitchenstewardship.com)
  • Parabens are rumored to be linked to breast cancer. (yahoo.com)
  • The notion that parabens cause breast cancer has been discredited," Schueller says. (yahoo.com)
  • Oct. 27, 2015 -- A new study has found that chemicals called parabens can spur the growth of certain types of breast cancer cells. (webmd.com)
  • Parabens have been in the news, as they have been linked to breast cancer. (rsc.org)
  • [6] This small study does not prove a causal relationship between parabens and breast cancer, but it is important because it detected the presence of intact parabens-unaltered by the body's metabolism-which is an indication of the chemical's ability to penetrate skin and remain in breast tissue. (safecosmetics.org)
  • But some think that parabens may be linked to breast cancer and fertility issues. (latimes.com)
  • The fuss started when a study linked parabens in deodorant to breast cancer. (truthinaging.com)
  • The study has since been discredited and the American Cancer Society has concluded that there is insufficient scientific evidence of parabens increasing breast cancer risk. (truthinaging.com)
  • It examined the distribution of five types of paraben at four different parts of the breast in tissue samples from 40 women who had undergone a mastectomy due to breast cancer. (www.nhs.uk)
  • It does not prove that parabens caused these cancers, and it does not suggest that parabens have any association with breast cancer development. (www.nhs.uk)
  • The study found that all 40 women with breast cancer had parabens in their breast tissue, but it is not known whether this would be the case in all women with breast cancer. (www.nhs.uk)
  • Parabens were found in all breast cancer samples tested, but it is not known whether this is representative of all breast cancers. (www.nhs.uk)
  • This laboratory study examined breast tissue samples, taken from women who had undergone a mastectomy for breast cancer , to see if they contained parabens (modified versions of the chemical p-hydroxybenzoic acid). (www.nhs.uk)
  • Well, studies show that parabens artificially mimic estrogens in the body, leading to a host of problems including extra fat storage, male breast growth, metabolic, developmental, hormonal and neurological disorders, various cancers including and most notably, breast cancer. (100percentpure.com)
  • In the past decade, research has concluded that parabens were present in 99% of breast cancer tissues sampled. (100percentpure.com)
  • When parabens are absorbed into the skin, they mimic estrogens, disrupt our endocrine systems and lead to breast cancer in both men and women. (100percentpure.com)
  • Let me explain: Controversy around parabens arose after the publication of a 2004 study by Dr. Philippa Darbre, who found traces of parabens in breast cancer tissues. (truthinaging.com)
  • I bring this up because people interpreting Dr. Darbre's study imply that parabens in products caused the parabens to appear in breast cancer tissue. (truthinaging.com)
  • This study, which was quite small, does not prove that Parabens cause breast cancer. (holisticwisdom.com)
  • One of the most well-known of these is that using anti-perspirants can increase the risk of developing breast cancer, because underarm shaving allows chemicals like parabens to be absorbed into the lymph nodes by the small cuts caused by the razor. (hubpages.com)
  • In the findings, the substance (parabens) was not shown to cause or contribute to breast cancer but they were present and seemed to originate from a substance applied to the skin. (beautynewsnyc.com)
  • Although these parabens work by mimicking the growth effects of estrogens on breast cancer cells, previous studies have found no concrete evidence that points to their use having tangible effects on these cells. (mindfood.com)
  • Although parabens are known to mimic the growth effects of estrogens on breast cancer cells, some consider their effect too weak to cause harm," said lead investigator Dale Leitman , a gynaecologist and molecular biologist at UC Berkeley and an adjunct associate professor of nutritional sciences and toxicology. (mindfood.com)
  • According to Leitman, initial studies "fail to take into account that parabens could interact with other types of signaling molecules in the cells to increase breast cancer risk. (mindfood.com)
  • A 2008 opinion on parabens from the European Commission's Scientific Committee on Consumer Products states that "methyl paraben and ethyl paraben are not subjects of concern," but that "the safety assessment of propyl and butyl paraben cannot be finalized yet. (latimes.com)
  • Rebecca Sutton, a scientist at the Environmental Working Group, a nonprofit advocacy organization, says her group is most concerned about propyl and butyl paraben too. (latimes.com)
  • After stratification, methyl and propyl paraben were suggestively negatively associated with estradiol at the first time point (16-20 weeks), and suggestively positively associated with estradiol at the second time point (24-28 weeks). (northeastern.edu)
  • More and more major lines are adding paraben-free options. (savannahnow.com)
  • However, researchers in the United Kingdom have found traces of parabens in samples of breast tumours that have been removed and this demonstrates that they can accumulate in our bodies and have raised the flag that the risks of using them in skin care products and toiletries should probably be reassessed. (hubpages.com)
  • The study also found that the in vivo estrogenic activity of parabens is reduced by about three orders of magnitude compared to in vitro activity. (wikipedia.org)
  • The estrogenic activity of parabens increases with the length of the alkyl group. (wikipedia.org)
  • If you browse the personal care product aisles in any drug store, you are likely to see labels advertising that certain body washes, lotions, and other items are "paraben free. (ewg.org)
  • Parabens are most common in personal care products that contain significant amounts of water such as shampoos, conditioners, lotions and facial and shower cleansers and scrubs because they discourage the growth of microbes. (safecosmetics.org)
  • Babies tended to be heavier at birth, and more likely to become overweight by the time they were 8 years old when mothers used makeup, lotions and other common beauty products containing parabens while pregnant, the study found. (medscape.com)
  • Paraben is featured in a gazillion health and beauty products - think body lotions, mascara, conditioners and deodorants - you name it, it's in it! (superdrug.com)
  • Paraben is used in products like toners, lotions, blushes and foundations to stop them from being a breeding ground for mould and fungus. (superdrug.com)
  • Ethyl paraben sodium (CAS 94-13-2) Market Research Report 2018 aims at providing comprehensive data on ethyl paraben sodium market globally and regionally (Europe, Asia, North America, Latin America etc. (marketpublishers.com)
  • The report includes ethyl paraben sodium description, covers its application areas, manufacturing methods, patents. (marketpublishers.com)
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  • In addition to the above the report determines ethyl paraben sodium consumers. (marketpublishers.com)
  • Ethyl paraben sodium (CAS 94-13-2) Market Research Report 2018 contents were prepared and placed on the website in February, 2018. (marketpublishers.com)
  • Please note that Ethyl paraben sodium (CAS 94-13-2) Market Research Report 2018 is a half ready publication and contents are subject to change. (marketpublishers.com)
  • The headline is based on a laboratory study that investigated how a group of chemicals called parabens are deposited in human tissue. (www.nhs.uk)
  • an online database and app that helps consumers eat healthier, propyl paraben is in 49 widely-available processed foods, including Sara Lee cinnamon rolls, Weight Watchers cakes and La Banderita Corn Tortillas. (ewg.org)
  • Since parabens are widely found in so many different products, it can be hard to avoid them, even though many people have never heard of them at all. (wisegeek.com)
  • So, Kurunthachalam Kannan and colleagues wanted to examine the exposure of dogs and cats to parabens in commercially available pet food and analyze the substances in the animals' urine. (eurekalert.org)
  • We have developed a sensitive method for measuring BPA, 4-tert-octylphenol (tOP), benzophenone-3 (BP-3), one chlorophenols triclosan, and four parabens. (cdc.gov)
  • Urinary levels of triclosan and parabens are associated with aeroallergen and food sensitization. (nih.gov)
  • However, levels of the antimicrobial EDCs triclosan and parabens were significantly associated with allergic sensitization. (nih.gov)
  • Pre- and post-intervention urine samples were analyzed for phthalate metabolites, parabens, triclosan and BP-3 using high-performance liquid chromatography/tandem mass spectrometry. (cosmeticsandtoiletries.com)
  • Simultaneous identification and quantification by liquid chromatography of benzethonium chloride, methyl paraben and triclosan in commercial produc. (nih.gov)
  • A HPLC method has been developed which permits the quantification of methyl paraben, benzethonium chloride and triclosan in various samples of grapefruit seed extract (GSE). (nih.gov)
  • The detection wavelength was 254 nm for methyl paraben, and 275 nm for benzethonium chloride and triclosan. (nih.gov)
  • A 2004 study conducted by British researchers found traces of the chemical form of parabens in 18 of 20 breast tumor samples tested. (beautynewsnyc.com)
  • A team of scientists from the University of Granada (UGR), the Biohealth Research Institute in Granada (ibs.GRANADA), the city's San Cecilio University Hospital, and the Centre for Biomedical Research in Epidemiology and Public Health (CIBERESP) has found that 9 out of 10 pairs of socks for babies and children from 0-4 years old contain traces of bisphenol A and parabens. (ugr.es)
  • "We initially wanted to find out whether the parabens detected in urine from expectant mothers from the mother-child cohort had an impact on the development of their children's weight," ​ explains former UFZ researcher Professor Irina Lehmann, currently at the Berlin Institute of Health (BIH) and at Charité - Berlin University Hospital. (cosmeticsdesign-europe.com)
  • A recent study that tested 183 adults and children in California found parabens in 70% to 100% of their urine samples -- depending on the specific paraben they were looking for. (webmd.com)
  • Parabens are found in nearly all urine samples from U.S. adults regardless of ethnic, socioeconomic or geographic backgrounds. (safecosmetics.org)
  • Parabens are esters of para-hydroxybenzoic acid, from which the name is derived. (wikipedia.org)
  • To get a bit science-y, parabens are esters (a compound formed from acid and alcohol) of p-hydroxybenzoic acid. (latimes.com)
  • So, instead of worrying whether or not you should be using shampoos and conditioners that have parabens, why not just switch. (divine.ca)
  • We'll get you started with 6 great paraben-free shampoos and conditioners! (divine.ca)