Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
A family of small, non-enveloped DNA viruses infecting birds and most mammals, especially humans. They are grouped into multiple genera, but the viruses are highly host-species specific and tissue-restricted. They are commonly divided into hundreds of papillomavirus "types", each with specific gene function and gene control regions, despite sequence homology. Human papillomaviruses are found in the genera ALPHAPAPILLOMAVIRUS; BETAPAPILLOMAVIRUS; GAMMAPAPILLOMAVIRUS; and MUPAPILLOMAVIRUS.
Infections produced by oncogenic viruses. The infections caused by DNA viruses are less numerous but more diverse than those caused by the RNA oncogenic viruses.
A type of ALPHAPAPILLOMAVIRUS especially associated with malignant tumors of the CERVIX and the RESPIRATORY MUCOSA.
Tumors or cancer of the UTERINE CERVIX.
Vaccines or candidate vaccines used to prevent PAPILLOMAVIRUS INFECTIONS. Human vaccines are intended to reduce the incidence of UTERINE CERVICAL NEOPLASMS, so they are sometimes considered a type of CANCER VACCINES. They are often composed of CAPSID PROTEINS, especially L1 protein, from various types of ALPHAPAPILLOMAVIRUS.
A species of DELTAPAPILLOMAVIRUS infecting cattle.
A genus of DNA viruses in the family PAPILLOMAVIRIDAE. They preferentially infect the anogenital and ORAL MUCOSA in humans and primates, causing both malignant and benign neoplasms. Cutaneous lesions are also seen.
A type of human papillomavirus especially associated with malignant tumors of the genital and RESPIRATORY MUCOSA.
Pathological processes of the UTERINE CERVIX.
ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN and certain cyclin-dependent kinase inhibitors.
Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.
Deoxyribonucleic acid that makes up the genetic material of viruses.
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)
A type of ALPHAPAPILLOMAVIRUS causing recurrent respiratory PAPILLOMATOSIS; GENITAL WARTS; and other neoplasms.
The neck portion of the UTERUS between the lower isthmus and the VAGINA forming the cervical canal.
Collection of pooled secretions of the posterior vaginal fornix for cytologic examination.
The type species of KAPPAPAPILLOMAVIRUS. It is reported to occur naturally in cottontail rabbits in North America.
Benign epidermal proliferations or tumors; some are viral in origin.
A type of ALPHAPAPILLOMAVIRUS usually associated with GENITAL WARTS; and LARYNGEAL NEOPLASMS.
DNA probes specific for the identification of human papilloma virus.
Viral diseases which are transmitted or propagated by sexual conduct.
A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
Methods for detecting or typing the DNA of an ALPHAPAPILLOMAVIRUS in biological tissues and fluids.
Cytological preparation of cells collected from a mucosal surface and stained with Papanicolaou stain.
The interdisciplinary field concerned with the development and integration of behavioral and biomedical science, knowledge, and techniques relevant to health and illness and the application of this knowledge and these techniques to prevention, diagnosis, treatment, and rehabilitation.
Abnormal development of immature squamous EPITHELIAL CELLS of the UTERINE CERVIX, a term used to describe premalignant cytological changes in the cervical EPITHELIUM. These atypical cells do not penetrate the epithelial BASEMENT MEMBRANE.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Tumors or cancer of the ANAL CANAL.
Sexual activities of humans.
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
Tumor or cancer of the MALE GENITALIA.
Pathological processes involving the PENIS or its component tissues.
Tumors or cancer of the OROPHARYNX.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
A type of XIPAPILLOMAVIRUS causing alimentary carcinoma in cattle. It is related to Bovine papillomavirus 3.
A type of ALPHAPAPILLOMAVIRUS associated with high risk for anogenital neoplasms.
The terminal segment of the LARGE INTESTINE, beginning from the ampulla of the RECTUM and ending at the anus.
The examination, therapy or surgery of the cervix and vagina by means of a specially designed endoscope introduced vaginally.
Pathological processes involving the male reproductive tract (GENITALIA, MALE).
Proteins that form the CAPSID of VIRUSES.
A genus of DNA viruses in the family PAPILLOMAVIRIDAE, causing cutaneous lesions in humans. Infections exist in latent form in the general population and are activated under conditions of IMMUNOSUPPRESSION.
Excision of the prepuce of the penis (FORESKIN) or part of it.
Tumors or cancer of the VULVA.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra.
A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
Pathological processes of the VAGINA.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
Pathological processes involving the female reproductive tract (GENITALIA, FEMALE).
The male reproductive organs. They are divided into the external organs (PENIS; SCROTUM;and URETHRA) and the internal organs (TESTIS; EPIDIDYMIS; VAS DEFERENS; SEMINAL VESICLES; EJACULATORY DUCTS; PROSTATE; and BULBOURETHRAL GLANDS).
A cutaneous pouch of skin containing the testicles and spermatic cords.
Immunoglobulins produced in response to VIRAL ANTIGENS.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
Inflammation of the UTERINE CERVIX.
Immune status consisting of non-production of HIV antibodies, as determined by various serological tests.
Diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of body fluid. (Stedman, 26th ed)
Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.
Infections of the genital tract in females or males. They can be caused by endogenous, iatrogenic, or sexually transmitted organisms.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The infective system of a virus, composed of the viral genome, a protein core, and a protein coat called a capsid, which may be naked or enclosed in a lipoprotein envelope called the peplos.
Married or single individuals who share sexual relations.
Diseases due to or propagated by sexual contact.
Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.
The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed)
Simultaneous infection of a host organism by two or more pathogens. In virology, coinfection commonly refers to simultaneous infection of a single cell by two or more different viruses.
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
Tumors or cancer of the SKIN.
Cancers or tumors of the PENIS or of its component tissues.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.
The sexual attraction or relationship between members of the opposite SEX.
Administration of vaccines to stimulate the host's immune response. This includes any preparation intended for active immunological prophylaxis.
An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
MOLECULAR BIOLOGY techniques used in the diagnosis of disease.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses.
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Proteins found in any species of virus.
An autosomal recessive trait with impaired cell-mediated immunity. About 15 human papillomaviruses are implicated in associated infection, four of which lead to skin neoplasms. The disease begins in childhood with red papules and later spreads over the body as gray or yellow scales.
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).
A genus of DNA viruses in the family PAPILLOMAVIRIDAE, which cause cutaneous lesions in humans. They are histologically distinguishable by intracytoplasmic INCLUSION BODIES which are species specific.
Development of neutralizing antibodies in individuals who have been exposed to the human immunodeficiency virus (HIV/HTLV-III/LAV).
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Compounds, usually hormonal, taken orally in order to block ovulation and prevent the occurrence of pregnancy. The hormones are generally estrogen or progesterone or both.
A method (first developed by E.M. Southern) for detection of DNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.
Tumors or cancer of the VAGINA.
Tumors or cancer of the PALATINE TONSIL.
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
Educational institutions providing facilities for teaching and research and authorized to grant academic degrees.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A group of islands in Polynesia, in the north central Pacific Ocean, comprising eight major and 114 minor islands, largely volcanic and coral. Its capital is Honolulu. It was first reached by Polynesians about 500 A.D. It was discovered and named the Sandwich Islands in 1778 by Captain Cook. The islands were united under the rule of King Kamehameha 1795-1819 and requested annexation to the United States in 1893 when a provisional government was set up. Hawaii was established as a territory in 1900 and admitted as a state in 1959. The name is from the Polynesian Owhyhii, place of the gods, with reference to the two volcanoes Mauna Kea and Mauna Loa, regarded as the abode of the gods. (From Webster's New Geographical Dictionary, 1988, p493 & Room, Brewer's Dictionary of Names, 1992, p2330)
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
The functional hereditary units of VIRUSES.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
The study of the structure, growth, function, genetics, and reproduction of viruses, and VIRUS DISEASES.
The quantity of measurable virus in a body fluid. Change in viral load, measured in plasma, is sometimes used as a SURROGATE MARKER in disease progression.
Skin diseases caused by viruses.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Sexual attraction or relationship between males.
Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
Established cell cultures that have the potential to propagate indefinitely.
A country spanning from central Asia to the Pacific Ocean.
Individuals enrolled in a school or formal educational program.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
The frequency of different ages or age groups in a given population. The distribution may refer to either how many or what proportion of the group. The population is usually patients with a specific disease but the concept is not restricted to humans and is not restricted to medicine.
Former kingdom, located on Korea Peninsula between Sea of Japan and Yellow Sea on east coast of Asia. In 1948, the kingdom ceased and two independent countries were formed, divided by the 38th parallel.
Inhaling and exhaling the smoke of burning TOBACCO.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
A malignant epithelial tumor with a glandular organization.
Eukaryotic cell line obtained in a quiescent or stationary phase which undergoes conversion to a state of unregulated growth in culture, resembling an in vitro tumor. It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals.
Curved rows of HAIR located on the upper edges of the eye sockets.
Elements of limited time intervals, contributing to particular results or situations.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
The process by which a DNA molecule is duplicated.
The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.

Immunohistochemical expression of mdm2 and p21WAF1 in invasive cervical cancer: correlation with p53 protein and high risk HPV infection. (1/4024)

AIM: To investigate the immunocytochemical staining pattern of mdm2 and p21WAF1 proteins in invasive cervical cancer and to determine its relation with the expression of p53 and with the high risk HPV infection. METHODS: Immunocytochemistry for p53, mdm2, and p21WAF1 was performed in 31 paraffin embedded sections of invasive cervical cancer. The results were assessed by image analysis, evaluating for each protein the optical density of the immunostained area, scored as percentage of the total nuclear area. The presence of high risk human papillomavirus (HPV) infection was detected by using the polymerase chain reaction. RESULTS: Immunostaining for both mdm2 and p21WAF1 was correlated with p53 expression; however, the correlation between p53 and mdm2 (R = 0.49; p < 0.01) was more significant than between p53 and p21WAF1 (R = 0.31; p < 0.05); the less stringent correlation between p53 and p21WAF1 might reflect the p53 independent mechanisms of p21WAF1 induction. Similar average levels of p53, mdm2, and p21WAF1 immunostaining were found in the presence or absence of high risk HPV-DNA, without significant differences between the two groups. CONCLUSIONS: These data suggest that mdm2 and p21WAF1 proteins are expressed in invasive cervical cancer and that their immunocytochemical staining pattern is not abrogated by the presence of high risk HPV genomic sequences.  (+info)

Analysis of TSG101 tumour susceptibility gene transcripts in cervical and endometrial cancers. (2/4024)

Carcinoma of the uterine cervix is a common malignancy among women that has been found to show loss of heterozygosity in the chromosome 11p. Recent studies have localized the TSG101 gene in this region, and also demonstrated a high frequency of abnormalities of this gene in human breast cancer. To determine the role of the TSG101 gene in the carcinogenesis of cervical and uterine carcinoma, 19 cases of cervical carcinoma and five cases of endometrial carcinoma, as well as nearby non-cancerous tissue from the same patients, and 16 blood samples from healthy persons as normal control were analysed by Southern blot analysis of genomic DNA, reverse transcription of the TSG101 mRNA followed by PCR amplification and sequencing of the products. We found that abnormal transcripts of the TSG101 gene were common both in cancerous or non-cancerous tissues of the uterus and cervix and in normal peripheral mononuclear cells. There was no genomic deletion or rearrangement in spite of the presence of abnormal transcripts, and no definite relationship between the abnormal transcripts and HPV infection was found. Although the frequency of abnormal transcripts was higher in cancerous than in non-cancerous tissue, normal peripheral mononuclear cells also had abnormal transcripts. Given these findings, the role of the TSG101 gene as a tumour-suppressor gene should be re-evaluated. Because some aberrant transcripts could be found at the first PCR reaction, we suggest that the aberrant transcripts might be the result of imperfect minor splicesome products.  (+info)

Cervicovaginal human papillomavirus infection in human immunodeficiency virus-1 (HIV)-positive and high-risk HIV-negative women. (3/4024)

BACKGROUND: Human papillomavirus (HPV) infection is associated with precancerous cervical squamous intraepithelial lesions commonly seen among women infected with human immunodeficiency virus-1 (HIV). We characterized HPV infection in a large cohort of HIV-positive and HIV-negative women participating in the Women's Interagency HIV Study to determine the prevalence of and risk factors for cervicovaginal HPV infection in HIV-positive women. METHODS: HIV-positive (n = 1778) and HIV-negative (n = 500) women were tested at enrollment for the presence of HPV DNA in a cervicovaginal lavage specimen. Blood samples were tested for HIV antibody status, level of CD4-positive T cells, and HIV RNA load (copies/mL). An interview detailing risk factors was conducted. Univariate and multivariate analyses were performed. RESULTS: Compared with HIV-negative women, HIV-positive women with a CD4+ cell count of less than 200/mm3 were at the highest risk of HPV infection, regardless of HIV RNA load (odds ratio [OR] = 10.13; 95% confidence interval [CI] = 7.32-14.04), followed by women with a CD4+ count greater than 200/mm3 and an HIV RNA load greater than 20,000 copies/mL (OR = 5.78; 95% CI = 4.17-8.08) and women with a CD4+ count greater than 200/mm3 and an HIV RNA load less than 20,000 copies/mL (OR = 3.12; 95% CI = 2.36-4.12), after adjustment for other factors. Other risk factors among HIV-positive women included racial/ethnic background (African-American versus Caucasian, OR = 1.64; 95% CI = 1.19-2.28), current smoking (yes versus no; OR = 1.55; 95% CI = 1.20-1.99), and younger age (age < 30 years versus > or = 40 years; OR = 1.75; 95% CI = 1.23-2.49). CONCLUSIONS: Although the strongest risk factors of HPV infection among HIV-positive women were indicators of more advanced HIV-related disease, other factors commonly found in studies of HIV-negative women, including racial/ethnic background, current smoking, and age, were important in HIV-positive women as well.  (+info)

Risk factors for abnormal anal cytology in young heterosexual women. (4/4024)

Although anal cancers are up to four times more common in women than men, little is known about the natural history of anal human papillomavirus (HPV) infections and HPV-related anal lesions in women. This study reports on the prevalence of and risks for anal cytological abnormalities over a 1-year period in a cohort of young women participating in a study of the natural history of cervical HPV infection. In addition to their regularly scheduled sexual behavior interviews and cervical testing, consenting women received anal HPV DNA and cytological testing. Anal cytology smears were obtained from 410 women whose mean age was 22.5 +/- 2.5 years at the onset of the study. Sixteen women (3.9%) were found to have abnormal anal cytology: 4 women had low-grade squamous intraepithelial lesions (SILs) or condyloma; and 12 women had atypical cells of undetermined significance. Factors found to be significantly associated with abnormal anal cytology were a history of anal sex [odds ratio (OR), 6.90; 95% confidence interval (CI), 1.7-47.2], a history of cervical SILs (OR, 4.13; 95% CI, 1.3-14.9), and a current anal HPV infection (OR, 12.28; 95% CI, 3.9-43.5). The strong association between anal intercourse and the development of HPV-induced SILs supports the role of sexual transmission of HPV in anal SILs. Young women who had engaged in anal intercourse or had a history of cervical SILs were found to be at highest risk.  (+info)

Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. I. Differential T-helper and IgG responses in relation to HPV infection and disease outcome. (5/4024)

T-helper (Th) cell-dependent IL-2 production and plasma IgG responses to virus-like particles consisting of the human papillomavirus type 16 (HPV-16) major capsid protein L1 (L1-VLP) were determined in patients with cytological evidence of cervical intraepithelial neoplasia (CIN) participating in a non-intervention prospective cohort study. IgG responses were associated with HPV-16 persistence and high-grade CIN lesions, while high frequencies of Th responses were observed in patients with both virus clearance and virus persistence, irrespective of CIN grade. The IgG response was found in conjunction with an IL-2 response to L1-VLP in 87% of the patients. Recognition of the HPV-16 L1 Th epitope (amino acids 311-335) was found to be more closely associated than recognition of L1-VLP as a whole to HPV exposure and CIN development. Among the HPV-16+ patients included in this study, those showing a Th response to amino acids 311-335 were more likely to carry the HLA DRB1*11/DQB1*0301 haplotype, while those showing an IgG response to L1-VLP were more likely to carry DRB1*0101/DQB1*0501. However, neither cell-mediated nor humoral immune responses against HPV-16 L1 appear to be sufficient for the natural control of HPV infection and CIN development.  (+info)

Immune responses against human papillomavirus (HPV) type 16 virus-like particles in a cohort study of women with cervical intraepithelial neoplasia. II. Systemic but not local IgA responses correlate with clearance of HPV-16. (6/4024)

To investigate whether there is an association between local or systemic IgG and IgA responses against human papillomavirus (HPV) type 16 virus-like particles (VLP) containing L1 and L2 and the possible influence of these responses on clearance of HPV-16 and its associated lesions, cervical mucus samples from 125 patients and plasma samples from 100 patients, all participating in a non-intervention cohort study of women with abnormal cytology, were analysed. The results show that local IgG and IgA HPV-16 VLP-specific antibodies do not correlate with virus clearance. However, systemic IgG responses were more frequently detected in patients with a persistent infection (11/24) compared with patients with cleared HPV-16 infections (3/28, P = 0.006). Furthermore, the ultimate development of high-grade lesions was associated with systemic VLP-specific IgG reactivity (P = 0.026). By contrast, systemic IgA responses were correlated with virus clearance (7/28 clearance compared with 1/24 persistence patients, P = 0.06). This correlation was statistically significant when only those clearance patients who tested HPV-16 DNA-positive at more than one visit were included in the analysis (5/11 compared with 1/24, P = 0.007). As these systemic IgA responses were not accompanied by local IgA responses, the systemic IgA responses in HPV-16 clearance patients are suggested to be a by-product of a successful cellular immune response induced at the local lymph nodes, mediated by cytokines.  (+info)

Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation. (7/4024)

Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down-regulated upon epithelial differentiation.  (+info)

Human papillomavirus (HPV) DNA copy number is dependent on grade of cervical disease and HPV type. (8/4024)

The association between human papillomavirus (HPV) DNA copy number and cervical disease was investigated. Viral DNA copy number for the most common high-risk HPV types in cervical cancer (types 16, 18, 31, and 45) was determined in cervical cytobrush specimens from 149 women with high-grade cervical intraepithelial neoplasias (CIN II-CIN III), 176 with low-grade CIN (CIN I), and 270 with normal cytology. Quantitative, PCR-based fluorescent assays for each of the HPV genotypes and for the beta-globin gene were used. The amount of cellular DNA increased significantly with increasing disease; thus, HPV was expressed as copies per microgram of cellular DNA. The assay had a dynamic range of >10(7), allowing documentation for the first time of the wide range of HPV copy numbers seen in clinical specimens. Median HPV DNA copy number varied by more than 10(4) among the viral types. HPV16 was present in the highest copy number; over 55% of HPV16-positive samples contained more than 10(8) copies/microgram. Median copy number for HPV16 showed dramatic increases with increasing epithelial abnormality, an effect not seen with the other HPV types. HPV16 increased from a median of 2.2 x 10(7) in patients with normal cytology, to 4.1 x 10(7) in CIN I patients, to 1.3 x 10(9) copies/microgram in CIN II-III patients. Even when stratified by cervical disease and viral type, the range of viral DNA copies per microgram of cellular DNA was quite large, precluding setting a clinically significant cutoff value for "high" copy numbers predictive of disease. This study suggests that the clinical usefulness of HPV quantitation requires reassessment and is assay dependent.  (+info)

RESULTS:. The 42 selected articles enrolled 4066 patients. It was observed that oral or oropharyngeal human papillomavirus infections were identified in 738 patients (18.2%; IC 95 17.6-18.8), varying between 0.0% and 91.9%. The prevalences of oral or oropharyngeal human papillomavirus infections were respectively 6.2%, 44.6%, 44.4%, 27.4%, 38.5% and 11.9% for healthy people, those with benign oral lesions, pre-malignant lesions, oral or oropharyngeal squamous cell carcinoma, risk groups (patients with genital human papillomavirus lesions or infected partners) and immunocompromised patients. The risk of human papillomavirus infection was estimated for each subgroup and it was evident that, when compared to the healthy population, the risk of human papillomavirus infection was approximately 1.5-9.0 times higher, especially in patients with an immunodeficiency, oral lesions and squamous cell carcinoma. The rates of the most well-known oncogenic types (human papillomavirus 16 and/or 18) also show ...
TY - JOUR. T1 - Type-Specific Human Papillomavirus Prevalence, Incident Cases, Persistence, and Associated Pregnancy Outcomes among HIV-Infected Women in Kenya. AU - Vyankandondera, Joseph. AU - Wambua, Sammy. AU - Irungu, Eunice. AU - Mandaliya, Kishor. AU - Temmerman, Marleen. AU - Ryan, Claire. AU - Mohamed, Yasmin. AU - Vanden Broeck, Davy. AU - Verhelst, Rita. AU - Chersich, Matthew F.. AU - Luchters, Stanley. PY - 2019/8/1. Y1 - 2019/8/1. N2 - Background Persistent infection with high-risk types of human papillomavirus (HPV) is the preeminent factor driving the development of cervical cancer. There are large gaps in knowledge about both the role of pregnancy in the natural history of HPV infection and the impact of HPV on pregnancy outcomes. Methods This single-site prospective cohort substudy, nested within an international multisite randomized controlled trial, assessed prevalence, incident cases, and persistence of type-specific HPV infection, and the association between persistence of ...
Distribution of Human Papilloma Virus Infections of Uterine Cervix among Women of Reproductive Age - a Cross Sectional Hospital-Based Study from North East India Human papilloma virus;cervical cancer;squamous epithelial lesion;PCR;NILM;India; Infection of the uterine cervix by human papilloma viruses (HPV) may be associated with cervical pre-cancer and invasive cervical carcinoma if left untreated. With advance in molecular techniques, it has become easier to detect the resence of HPV DNA long before the appearance of any lesion. This study concerned cervical scrape samples of 310 married non-pregnant women attending a gynecology outpatient department for both Pap and PCR testing to detect HPV DNA. Nested PCR using primers for L1 consensus gene with My9/My11 and GP6+/GP5+followed by multiplex PCR were carried out to detect HPV 16 and HPV18. Result: HPV prevalence was 11.9% out of which 3.67% cases of negative for intra-epithelial lesion or malignancy (NILM) and in 71.1% (27/38) of atypical cervical
Human papillomavirus infection is an infection by human papillomavirus (HPV). Most HPV infections cause no symptoms and resolve spontaneously. In some people, an HPV infection persists and results in warts or precancerous lesions. The precancerous lesions increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, or throat. Nearly all cervical cancer is due to HPV with two types, HPV16 and HPV18, accounting for 70% of cases. Between 60% and 90% of the other cancers are also linked to HPV. HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis. An HPV infection is caused by human papillomavirus, a DNA virus from the papillomavirus family, of which over 170 types are known. More than 40 types are transmitted through sexual contact and infect the anus and genitals. Risk factors for persistent HPV infections include early age of first sexual intercourse, multiple partners, smoking, and poor immune function. HPV is typically spread by sustained direct ...
TY - JOUR. T1 - A population-based cross-sectional study of age-specific risk factors for high risk human papillomavirus prevalence in rural Nigeria. AU - Clarke, Megan A.. AU - Gage, Julia C.. AU - Ajenifuja, Kayode O.. AU - Wentzensen, Nicolas A.. AU - Adepiti, Akinfolarin C.. AU - Wacholder, Sholom. AU - Burk, Robert D.. AU - Schiffman, Mark. PY - 2011/8/2. Y1 - 2011/8/2. N2 - Background: Cervical cancer, caused by persistent infection with carcinogenic human papillomavirus (HR-HPV), is particularly prevalent in Sub-Saharan Africa and is associated with a high mortality rate. Some studies in West Africa, including our own, have found unusually high HR-HPV across all ages with a slight peak in older women. This increased prevalence at older ages may complicate screen-and-treat programs, which are implemented in regions where HPV prevalence declines with age and typically target women between 30-49 years. A better understanding of the determinants of high HR-HPV prevalence at older ages is ...
TY - JOUR. T1 - High-risk human papillomavirus prevalence in self-collected cervicovaginal specimens from human immunodeficiency virus (HIV)-negative women and women living with HIV living in Botswana. AU - Castle, Philip E.. AU - Varallo, John E.. AU - Bertram, Margaret Mary. AU - Ratshaa, Bakgaki. AU - Kitheka, Moses. AU - Rammipi, Kereng. PY - 2020. Y1 - 2020. N2 - Background The prevalence of high-risk human papillomavirus (hrHPV) is poorly described overall and in women living with HIV (WLWH) and HIV-negative women living in Botswana, a high HIV and cervical cancer-burden country. We conducted a pilot study of self-collection and highrisk HPV testing for cervical screening, from which data on HPV prevalence was available. Methods From five health facilities in the Kweneng East District, 1,022 women aged 30-49 years were enrolled to self-collect their cervicovaginal specimen for hrHPV testing by the Xpert HPV Test (Cepheid, Sunnyvale, CA, USA). Crude and age group-adjusted hrHPV prevalence ...
Human Papillomavirus Infection Definition: Human papillomavirus infection (HPV infection) is an infection by human papillomavirus (HPV) that is passed
Although an oncogenic human papillomavirus (HPV) infection has been established as the necessary cause of cervical cancer, most HPV infections are transient and rarely progress to significant cervical lesions. Current research has focused on identifying factors associated with viral persistence and clearance. Low nutritional status might influence a womans risk of having a persistent HPV infection and progression of that infection to cervical dysplasia, or at higher levels increase the probability of clearing infections. The overall goal of this research was to determine the associations between serum carotenoid, tocopherol, and retinoic acid levels and cervical carcinogenesis among the Ludwig-McGill Cohort Study. A sub-cohort of 846 women, all of whom had HPV results available from four consecutive study visits in the first year of follow-up, had serum samples analyzed for circulating nutrients. We determined the variability of circulating retinoic acid levels over the four months in a sample ...
Background. Little is known about the type-specific prevalence of anal human papillomavirus (HPV) infection and risk factors for anal high-risk (HR) HPV infection in human immunodeficiency virus (HIV)-infected women. Methods. A cross-sectional study of anal and cervical HPV infection was nested within a gynecological cohort of HIV-infected women. Specimens were tested for type-specific DNA using a polymerase chain reaction-based assay. Results. The study population consisted of 311 women with a median age of 45.3 years, of whom 42.8% originated from sub-Saharan Africa and 96.8% were receiving combination antiretroviral therapy. The median CD4 + cell count was 612/μL, and the HIV load was |50 copies/mL in 84.1%. HR-HPV types were detected in the anal canal in 148 women (47.6%) and in the cervix in 82 (26.4%). HPV-16 was the most prevalent type in both the anal canal (13.2% of women) and the cervix (5.1%). In multivariable analysis, factors associated with prevalent anal HR-HPV infection were CD4 + count
OUTLINE: This is a multicenter study.. Patients undergo anal swab collection at baseline to obtain samples for anal cytology, anal human papillomavirus (HPV) typing, and other HPV-related testing (e.g., HPV viral load). Digital rectal examinations (DRE) are also performed as part of the baseline physical examination. Female patients also undergo cervical swab collection for cervical HPV testing and cytology, as well as colposcopy (if available) of the cervix and vulvovaginal region to completely assess lower genital tract HPV-related lesions. At sites where high-resolution anoscopy (HRA) is available, patients are encouraged, but not required, to have an HRA with biopsy of any visualized lesions within 30 days of collection of the swabs.. After baseline assessments, patients undergo treatment with the investigative agent according to the study protocol requirements. If study treatment continues beyond 6 months, additional anal and cervical swabs are obtained for anal and cervical HPV and ...
OUTLINE: This is a multicenter study.. Patients undergo anal swab collection at baseline to obtain samples for anal cytology, anal human papillomavirus (HPV) typing, and other HPV-related testing (e.g., HPV viral load). Digital rectal examinations (DRE) are also performed as part of the baseline physical examination. Female patients also undergo cervical swab collection for cervical HPV testing and cytology, as well as colposcopy (if available) of the cervix and vulvovaginal region to completely assess lower genital tract HPV-related lesions. At sites where high-resolution anoscopy (HRA) is available, patients are encouraged, but not required, to have an HRA with biopsy of any visualized lesions within 30 days of collection of the swabs.. After baseline assessments, patients undergo treatment with the investigative agent according to the study protocol requirements. If study treatment continues beyond 6 months, additional anal and cervical swabs are obtained for anal and cervical HPV and ...
In the literature, data on the prevalence of human papillomavirus (HPV) infection in men vary significantly and the exact distribution of specific genotypes is still unclear. As infections usually occur without symptoms, men might only attend their hospital clinic when they have a specific concern, being in most cases genital warts (condylomas), which are often caused by low-risk HPV genotypes. The aim of this study was to assess HPV genotype distribution and prevalence among men attending hospital for HPV-associated conditions and to evaluate infection-associated factors. Samples from men with clinical manifestations of HPV-related infections seen during 2007-2012 at the Clinical Microbiology and Infectious Control Department at Basurto University Hospital were genotyped using Linear Array HPV Genotyping Test kit (Roche Molecular Diagnostics, Germany). Data on probable risk factors were collected and investigated for possible association. Of 184 anogenital samples, 138 (75 %) were tested as positive
TY - JOUR. T1 - Human papillomavirus infection in women with and without cervical cancer in Karachi, Pakistan. AU - Raza, S A. AU - Franceschi, S. AU - Pallardy, S. AU - Malik, F R. AU - Avan, B I. AU - Zafar, A. AU - Ali, S H. AU - Pervez, S. AU - Serajuddaula, S. AU - Snijders, P J F. AU - van Kemenade, F J. AU - Meijer, C J L M. AU - Shershah, S. AU - Clifford, G M. PY - 2010/4/20. Y1 - 2010/4/20. N2 - BACKGROUND: No data exist on the population prevalence of, or risk factors for, human papillomavirus (HPV) infection in predominantly Muslim countries in Asia. METHODS: Cervical specimens were obtained from 899 married women aged 15-59 years from the general population of Karachi, Pakistan and from 91 locally diagnosed invasive cervical cancers (ICCs). HPV was detected using a GP5+/6+ PCR-based assay. RESULTS: The prevalence of HPV in the general population was 2.8%, with no evidence of higher HPV prevalence in young women. The positivity of HPV was associated with womens lifetime number of ...
Research presented at the 2017 American Society of Clinical Oncology showed that although human papillomavirus (HPV) vaccine reduces the rate of oral HPV infection, the vaccine is still underutilized among teens and young adults.. -----. Related Content. HPV vaccination tied to population-level drop in cervical neoplasia rates. Fewer Incidences of Cervical Intraepithelial Neoplasia With HPV Vaccine. -----. Rates of HPV-caused oral cancers continue to rise every year in the United States, particularly among men. And yet, no clinical trial has evaluated the potential use of the HPV vaccine for the prevention of oral HPV infections that could lead to cancer, Maura L Gillison, MD, PhD, professor of medicine at the University of Texas MD Anderson Cancer Center, said in a press release. Given the absence of gold-standard, clinical trial data, we investigated whether HPV vaccine has had an impact on oral HPV infections among young adults in America.. The researchers studied 2627 young adults aged ...
Discussion. Genital HPV infection is the most common sexually transmitted disease. Taking into consideration of all the cervical cancer cases, 99,8% of the patients were infected by HPV. HPV infection may cause either genital wart, precancerous cervical lesions or cervical cancer. While more than 100 HPV subtypes exist, 30 subtypes may lead to infection in human. According to the oncogenicity potential, HPV types are classified as high risk (HR; type 16, 18, 31, 45, 51, 52, 59, 68) and low risk (LR; type 6 and 11) (1-4).. HPV infection prevalence exhibits regional variations. The incidence of HPV among 14-59 years of age Americans is 26,8% and the most common HPV subtype is type 6 (1,3%) (14), while this incidence is 17% in Spaniens and the most common HPV subtype is type 16 and 18 (15). On the other hand, among Indian women, type 16 is the most common HPV subtype and the incidence is 7,6% (16), in Denmark the percentage of the HPV infected women is 26,4 % type 16 is the most common one (6,0%) ...
Burden of Human Papilloma Virus Infection and Related Comorbidities in Men: Implications for Research, Disease Prevention and Health Promotion among Hispanic Men
We present the burden of human papillomavirus (HPV)-related cancers (cancers of the cervix, anogenital areas, and oral cavity and pharynx) in terms of incidence and mortality, for the countries of the Asia Pacific region. The region contains more than half of the world population, and manifests a wide geographic diversity in the prevalence of infection with HPV, and of incidence (and mortality) rates of cancer of the cervix. In general, rates of cancer of the cervix have declined since the 1960s; 67% of cases are associated with HPV-16 and 18. The incidence of other anogenital cancers is low, especially in Asian populations; however, cancers of the mouth and pharynx show a wide range of rates, determined by exposures such as oral tobacco and alcohol and for cancer of the lip, ultraviolet radiation. We also present the estimates of the occurence of genital warts--largely caused by HPV 6 and 11--and the HPV type distribution in the spectrum of women with normal cytology, cervical lesions, and cervical
Telomere maintenance is crucial in carcinogenesis and tumor progression. The results of a previous study from the authors indicated that infection with high-risk human papillomavirus (HR-HPV) types 16, 18, and 58 was a risk factor for esophageal squamous cell carcinoma (ESCC) in the Shantou region of China. In the current study, the authors explored the association between HR-HPV infection, telomere length (TL), and DNA methylation and their significance in the prognosis of patients with ESCC....
TY - JOUR. T1 - Hybrid capture 2 is as effective as PCR testing for high-risk human papillomavirus in head and neck cancers. AU - Hooper, Jody E.. AU - Hebert, Jessica F.. AU - Schilling, Amy. AU - Gross, Neil D.. AU - Schindler, Joshua. AU - Lagowski, James P.. AU - Kulesz-Martin, Molly. AU - Corless, Christopher. AU - Morgan, Terry. PY - 2015/4/22. Y1 - 2015/4/22. N2 - High-risk human papillomavirus (HPV) infection is a common cause of oropharyngeal squamous cell carcinoma, especially in young male nonsmokers. Accurately diagnosing HPV-associated oral cancers is important, because they have a better prognosis and may be treated differently than smoking-related oral carcinomas. Various methods have been validated to test for high-risk HPV in cervical tissue samples, and they are in routine clinical use to detect dysplasia before it progresses to invasive disease. Similarly, future screening for HPV-mediated oropharyngeal dysplasia may identify patients before it progresses. Our objective was to ...
TY - JOUR. T1 - Human papillomavirus therapy for the prevention and treatment of cervical cancer. AU - Khleif, Samir N.. PY - 2003/4/1. Y1 - 2003/4/1. N2 - Cervical carcinoma is associated with human papillomavirus infection. Proliferation of cancer cells depends on the continual expression of the E6 and E7 viral oncogenes. This article includes treatment strategies that can interfere with expression or function of the proteins and immunotherapeutic approaches that can eliminate cells that express E6 and E7 proteins.. AB - Cervical carcinoma is associated with human papillomavirus infection. Proliferation of cancer cells depends on the continual expression of the E6 and E7 viral oncogenes. This article includes treatment strategies that can interfere with expression or function of the proteins and immunotherapeutic approaches that can eliminate cells that express E6 and E7 proteins.. KW - Cervical Cancer. KW - Cervical Cancer Cell. KW - Cervical Intraepithelial Neoplasia. KW - Hairpin ...
Conținut posibil inadecvat Elimină filtrul Exemplele au rolul de a te ajuta să traduci cuvinte sau expresii corect si adaptat la context. Bacterial vaginosis is associated with uterine cervical human papillomavirus infection: a meta-analysis. Gynecol Oncol.
We report a case of disseminated human papillomavirus infection that developed in a patient while receiving efalizumab for the treatment of psoriasis. This infection progressed for several months after efalizumab treatment had been stopped. All human papillomavirus lesions completely resolved after 10 weeks of therapy with a combination of pegylated interferon and ribavirin.. ...
Figure 1. Prevalence of the 15 most common HPV genotypes in 5,910 HPV-positive LSILs by region. *, Denominators of HPV-positive LSIL vary by HPV type, from 2,516 to 5,910 for all regions, from 268 to 2,746 for Europe, from 1,640 to 1,943 for North America, from 466 to 874 for South/Central America, from 62 to 178 for Africa, and from 160 to 169 for Asia. †, In Asia, upper 95% CI for HPV16 is 39.6%, and HPV53 is not shown because the denominator was 33 cases only. ...
Determinants of genital human papillomavirus (HPV) persistence in 393 women initially cytologically normal were investigated by testing them for HPV DNA twice over a median interval of 14.9 months. At each visit, interview information was obtained and a cervicovaginal lavage sample was collected for …
TY - JOUR. T1 - Incident cervical HPV infections in young women. T2 - Transition probabilities for CIN and infection clearance. AU - Insinga, Ralph P.. AU - Perez, Gonzalo. AU - Wheeler, Cosette M.. AU - Koutsky, Laura A.. AU - Garland, Suzanne M.. AU - Leodolter, Sepp. AU - Joura, Elmar A.. AU - Ferris, Daron G.. AU - Steben, Marc. AU - Hernandez-Avila, Mauricio. AU - Brown, Darron R.. AU - Elbasha, Elamin. AU - Muñoz, Nubia. AU - Paavonen, Jorma. AU - Haupt, Richard M.. PY - 2011/2/1. Y1 - 2011/2/1. N2 - Background: We describe transition probabilities for incident human papillomavirus (HPV) 16/18/31/33/35/45/52/58/59 infections and cervical intraepithelial neoplasia (CIN) 1 lesions. Methods: Women ages 16 to 23 years underwent cytology and cervical swab PCR testing for HPV at approximately 6-month intervals for up to 4 years in the placebo arm of an HPV vaccine trial. The cumulative proportion of incident HPV infections with diagnosed CIN, clearing (infection undetectable), or persisting ...
Human papillomavirus infection in papillomas and nondiseased respiratory sites of patients with recurrent respiratory papillomatosis using the polymerase chain
Current cervical cancer screening guidelines recommend a Pap test every 3 years for women age 21-65 years, or for women 30-65 years who want to lengthen the screening interval, a combination of Pap test and high-risk human papilloma virus testing (co-testing) every 5 years. Little population-based data are available on human papilloma virus test utilization and human papilloma virus infection rates. The objective of this study was to examine the patient-level, cervical cancer screening, and area-level factors associated with human papilloma virus testing and infection among a diverse sample of uninsured and underinsured women enrolled in the New Jersey Cancer Early Education and Detection (NJCEED) Program. We used data for a sample of 50,510 uninsured/underinsured women, age ≥ 29 years, who screened for cervical cancer through NJCEED between January 1, 2009 and December 31, 2015. Multivariable logistic regression models were used to estimate associations between ever having a human papilloma virus
Human Papillomavirus Infection Test - Review how anyone can, with safe natural methods, effortlessly cure HPV infections and issues, such as abnormal Pap smears and cervical dysplasia, and thereby bypass unhealthy surgery.
In a study in Malawi, HIV-infected women were three times more likely than uninfected women to have persistent human papillomavirus infections (HPV), and twice as likely to have cervical abnormalities, according to NIAID-supported investigators and their colleagues. HPV infection is causally associated with cervical cancer, the most common malignancy among women in the developing world. Scientists estimate that worldwide 500,000 new cases of cervical cancer and 300,000 related deaths occur annually.. As reported in the March 1996 Journal of Infectious Diseases, the researchers found squamous epithelial lesions in 15 percent of 116 HIV-positive women, and 7 percent of 152 HIV-negative women. This heightened occurrence of cervical lesions probably resulted from a greater overall frequency of HPV infections (48 percent vs. 23 percent) in the HIV-positive group, write Paolo G. Miotti, M.D., of NIAIDs Division of AIDS, Keerti V. Shah, M.D., of The Johns Hopkins University School of Hygiene and ...
According to the National Cancer Institute, The most common test[which?] detects DNA from several high-risk HPV types, but it cannot identify the type(s) that are present. Another test[which?] is specific for DNA from HPV types 16 and 18, the two types that cause most HPV-associated cancers. A third test[which?] can detect DNA from several high-risk HPV types and can indicate whether HPV-16 or HPV-18 is present. A fourth test[which?] detects RNA from the most common high-risk HPV types. These tests can detect HPV infections before cell abnormalities are evident.. Theoretically, the HPV DNA and RNA tests could be used to identify HPV infections in cells taken from any part of the body. However, the tests are approved by the FDA for only two indications: for follow-up testing of women who seem to have abnormal Pap test results and for cervical cancer screening in combination with a Pap test among women over age 30. [107]. In April 2011, the Food and Drug Administration approved the cobas HPV ...
Screening-ul este realizat prin examinarea ginecologic[9,10] completat cu testul citologic Babe Papanicolau[6] la intervale regulate de Fig 6. Human papillomavirus or HPV parazitii vs politie Manifestările cutanate ale infecţiei cu virusul papiloma uman Human papillomavirus skin lesions According human papiloma virus lesions some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Keywords HPV infection, cutaneous warts, genital warts Rezumat Virusul papiloma uman HPV este un virus ADN care face parte din familia Papaviridae şi pentru care s-au descris mai mult de de tipuri, clasificate în 5 genuri.
RATIONALE: Gathering information about human papillomavirus infection of the mouth in young men may help doctors learn more about risk factors for oroph
This is the first study from Curaçao to show systematic data on HPV prevalence in cervical cancer and CIN lesions. Interestingly, although the prevalences of HPV16 (38.5%) and HPV18 (13.5%) in cervical cancer of women from Curaçao are still the most prevalent HPV genotypes, their prevalence is lower compared with the world prevalence.19-21. The prevalence of vaccine types HPV31, HPV52, HPV58 and HPV X (DEIA pos. and LiPA neg.) for each HPV type was 3.8%, in total 15.2%. In ADC (n=15), HPV 18 (40.0%), HPV16 (26.7%) and HPV45 (13.3%) were the most prevalent HPV types. Twelve cervical cancers were found to be HPV negative.. We performed several experiments to substantiate absence of HPV in cervical cancer and exclude experimental causes. Review of the slides by two pathologists did not change the diagnosis, and repeated HPV testing and genotyping with SPF10 yielded identical results. Inadequate DNA quality could be excluded by parallel testing with a duplex real-time PCR targeting the human ...
This is the first UK cohort study of carcinogenic HPV infection in women recruited at educational institutions rather than from healthcare facilities. It provides useful baseline data on HPV infection in England before the introduction of HPV immunisation. It enabled some investigation of the association of carcinogenic HPV infection with concurrent C trachomatis, M genitalium, N gonorrhoeae, or bacterial vaginosis. More than a third of the women returning follow-up samples were teenagers, many from ethnic minorities. Although black ethnicity was associated with prevalent and incident carcinogenic HPV infection in univariate analysis, it was not a significant independent risk factor for infection. Finally the study provides new information on demographics, smoking, and sexual behaviour related to carcinogenic HPV infection in England.. The main weakness is the study was not population based. This limits generalisability of our findings. However, these data may be the best currently available ...
Objectives:To assess the associations between microbiological markers of vaginal dysbiosis and incident/cleared/type-swap/persistent high-risk human papillomavirus (hrHPV) infection; and incident/cured/cleared/persistent high-grade cervical intraepithelial neoplasia (CIN2+) while controlling for per
Screening with cervical cytology and/or testing for multiple oncogenic HPV types can lead to the detection of high-grade precancerous cervical lesions and cervical cancer. High-risk HPV genotypes are necessary for the development of cervical cancer. HPV types 16 and 18 are the most carcinogenic genotypes, accounting for 55-60% and 10-15% of all cervical cancers, respectively. Low-risk HPV types are unrelated to cervical cancer and have no clinical role in cervical cancer screening or the evaluation of women with abnormal cytology.. Conventional or liquid-based cytology, with or without reflex to hrHPV testing, is the recommended screening method in women 21-29 years of age and should be performed every 3 years. Cotesting is defined as screening by cytology and HPV testing, and is the preferred screening method in women 30 years and older. This method is more sensitive than cytology alone at detecting cervical abnormalities and has the potential to enable both increased disease detection and ...
HPV- Human Papillomavirus Infection - By: Brooke Covington by Brooke C | This newsletter was created with Smore, an online tool for creating beautiful newsletters for for educators, nonprofits, businesses and more
The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in men who have sex with men, according to a new study published in the December 15 issue of The Journal of Infectious Diseases, now available online.
Thirty-eight cases were well differentiated carcinoma and 14 cases were metode de detoxifiere differentiated carcinoma. Vindecarea este de asemenea influenţată şi de diverşi human papillomavirus infection e factori din mediul local: hormoni sexuali, microbiotă. Chiar şi persoanele care nu administrează vaccinurile ar trebui să le recomande
Conclusions Human immunodeficiency virus-positive men have a high burden of genital HPV infection and AGW. The ART and HPV vaccine could reduce this burden....
Background: Human papillomavirus (HPV) is a common sexually transmitted infection (STI) that may cause cervical cancer and other malignancies including those of the vulva, anus, vagina, penis, head and neck. In most Asian countries including India, cervical cancer is the second most common cancer in women. Awareness about HPV and cervical cancer, use of vaccines can be very helpful in prevention, control and early diagnosis of cervical cancer. Methods: A cross-sectional study was carried out among students from Mumbai University, India during May - June 2017. Two hundred students were approached to participate in the study of which 142 were selected to participate (males: 54; females: 88). Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23. Results: Participants had fair knowledge (61% average) about HPV, whereas knowledge about symptoms, prevention and spread of HPV was very poor i.e. 18%. Knowledge about HPV vaccine was 50% and 78% participants had
Background: Human papillomavirus (HPV) is a common sexually transmitted infection (STI) that may cause cervical cancer and other malignancies including those of the vulva, anus, vagina, penis, head and neck. In most Asian countries including India, cervical cancer is the second most common cancer in women. Awareness about HPV and cervical cancer, use of vaccines can be very helpful in prevention, control and early diagnosis of cervical cancer. Methods: A cross-sectional study was carried out among students from Mumbai University, India during May - June 2017. Two hundred students were approached to participate in the study of which 142 were selected to participate (males: 54; females: 88). Pretested questionnaire was distributed and collected data was analyzed using IBM SPSS version 23. Results: Participants had fair knowledge (61% average) about HPV, whereas knowledge about symptoms, prevention and spread of HPV was very poor i.e. 18%. Knowledge about HPV vaccine was 50% and 78% participants had
Background: Cervical cancer (CC) is the fourth most commonly diagnosed cancer among women. Ghana is a low-middle- income country with annual diagnosed cases of 3,151 and 2,119 deaths. The high prevalence rate of cervical cancer in Ghana is mainly due to ineffective preventive measures and insufficient knowledge about the disease. Therefore, our objective was to evaluate the level of knowledge and awareness of cervical cancer and attitude toward human papillomavirus and its vaccine among Ghanaians.Methods: This descriptive cross-sectional survey on the awareness of cervical cancer and attitude toward human papillomavirus and its vaccine was carried out from March 2019 to February 2020. SPSS v. 23.0 was used in the data analysis. The participants demographic characteristics, knowledge of cervical carcinoma, human papillomavirus vaccine and HPV, and the likelihood to be vaccinated were represented as percentages and frequencies. The difference between males and females was assessed using the chi-square
Background: We assessed the association of human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) with various characteristics, CD4 count and use of combination antiretroviral therapy (cART) among HIV-positive women. Methods: Cross-sectional study of 498 HIV-positive women who underwent HPV PCR-based testing, cytology, and systematic cervical biopsy. Results: In all, 68.7% of women were HPV-positive, 52.6% had high-risk (hr) HPV, and 40.2% multiple type infections. High-risk human papillomavirus-positivity did not vary significantly by age but it was negatively associated with education level. The most frequent types in 113 CIN2/3 were HPV16 (26.5%), HPV35 (19.5%), and HPV58 (12.4%). CD4 count was negatively associated with prevalence of hrHPV (Po0.001) and CIN2/3 among non-users of cART (P¼0.013). Combination antiretroviral therapies users (X2 year) had lower hrHPV prevalence (prevalence ratio (PR) vs non-users¼0.77, 95% confidence interval (CI): 0.61-0.96) and multiple
The current study extended a previous investigation on the obesity-HPV association from a specific age group (aged 35-60) [12] to adult women in general (aged 20-59). Overall, we found a null or weak association between obesity or central obesity and HPV infection in this nationally-representative adult female population. However, subgroup analysis showed that obese or centrally-obese women had a significantly reduced HR-HPV infection among those who reported an early sex debut (,16 years) or those included in the fasting subpopulation. We proposed three potential mechanisms for these observed negative correlations.. First, despite the early sex debut, adult women with excessive adiposity might have a lower HPV burden than women with normal BMI or WC. Early studies on adolescents have consistently linked early sex debut to an increased risk for sexually transmitted infections (STI), including HPV infection [30, 31]. The heightened STI risks were reportedly mediated by concomitant risky behaviors ...
A groundbreaking study published in the Asian Pacific Journal of Cancer Prevention, titled, Clearance of Cervical Human Papillomavirus Infection by Topical Application of Curcumin and Curcumin Containing Polyherbal Cream: A Phase II Randomized Controlled Study, reveals that vaccination and watchful waiting are not the only recourse against HPV infection.. The study is believed to be the first of its kind to find an effective and safe therapeutic intervention for the clearance of established cervical human papillomavirus (HPV) infection. Moreover, the study confirmed that HPV infection is self-limiting and clears on its own in 73.3% of the untreated placebo group within 37 days.. The researchers evaluated the effectiveness of two herbal interventions in eliminating HPV infection from the cervix of women who were determined to have HPV infection through Pap smear and HPV DNA tests (PCR), but whose condition had not yet progressed to high grade cervical neoplasias (i.e. cervical ...
Cervical cancer is by far the most common HPV-related disease. About 99.7% of cervical cancer are caused by persistent genital high-risk human papillomavirus (HPV) infection. Worldwide, cervical cancer is one of the most common cancer in women with an estimated 528,000 new cases reported in 2012. Most HPV infections clear spontaneously but persistent infection with the oncogenic or high-risk types may cause cancer of the oropharynx and anogenital regions. The virus usually infects the mucocutaneous epithelium and produces viral particles in matured epithelial cells and then causes a disruption in normal cell-cycle control and the promotion of uncontrolled cell division leading to the accumulation of genetic damage. There are currently two effective prophylactic vaccines against HPV infection in many developed countries and these comprise of HPV types 16 and 18, and HPV types 6, 11, 16 and 18 virus-like particles. HPV testing in the secondary prevention of cervical cancer is clinically valuable in
The establishment of Human Papillomavirus HPV infection as a necessary risk factor for about 95% of cervical cancers has over the past few years raised the question of how this knowledge should best be used for optimization of cervical cancer screening programs. Key features of the epidemiology of HPV infection are now known. The incidence and...
OBJECTIVE--To assess prevalence, incidence and potential risk factors of human papillomavirus (HPV) infection among heterosexual men and women with multiple partners and to identify niches of HPV-infection. DESIGN--A prospective study of heterosexual men and women with multiple partners attending an STD clinic as participants in a study on HIV from May 1988 until January 1991. Routine STD examination and physical examination using colposcopy were performed, interviews with standardised questionnaires were administered. Specimens for HPV DNA detection by polymerase chain reaction were collected from multiple sites of the genital, anorectal and oral regions. In women cervical cytology was performed. SETTING--The STD Clinic of the Municipal Health Service of Amsterdam. PARTICIPANTS--162 women and 85 men entered the study, 110 women and 48 men were followed up. RESULTS--At entry of the study 37 (23%) women and 24 (28%) men were found positive for HPV DNA at any site. Only in one woman was oral ...
Anal high-risk human papillomavirus infection and high-grade anal intraepithelial neoplasia detected in women and heterosexual men infected with human immunodeficiency virus Sumanth Gandra, Aline Azar, Mireya WessolosskyDivision of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USABackground: Although anal high-risk human papillomavirus (HR-HPV) infection and anal cytological abnormalities are highly prevalent among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM), there are insufficient data on these abnormalities among HIV-infected heterosexual men (HSM) and women. In this study, we evaluated the prevalence of anal HR-HPV, cytological abnormalities, and performance of these screening tests in detecting high-grade anal intraepithelial neoplasia (AIN2+) among our cohort of HIV-infected MSM and non-MSM (HSM and women).Methods: A single-center, retrospective cohort study was conducted with HIV-infected individuals who underwent anal
To investigate the incremental cost effectiveness of two dose human papillomavirus vaccination and of additionally giving a third dose. Cost effectiveness study based on a transmission dynamic model of human papillomavirus vaccination. Two dose schedules for bivalent or quadrivalent human papillomavirus vaccines were assumed to provide 10, 20, or 30 years vaccine type protection and cross protection or lifelong vaccine type protection without cross protection. Three dose schedules were assumed to give lifelong vaccine type and cross protection. United Kingdom. Males and females aged 12-74 years. No, two, or three doses of human papillomavirus vaccine given routinely to 12 year old girls, with an initial catch-up campaign to 18 years. Costs (from the healthcare providers perspective), health related utilities, and incremental cost effectiveness ratios. Giving at least two doses of vaccine seems to be highly cost effective across the entire range of scenarios considered at the quadrivalent ...
TY - JOUR. T1 - Perception, knowledge and attitude towards human papilloma virus infection and vaccination for cervical cancer prevention among university students. AU - Shafiee, Mohamad Nasir. AU - Kah Teik, Chew. AU - Kampan, Nirmala @ Chandralega. AU - Lim, Pei Shan. AU - Omar, Mohd Hashim. AU - Abdul Ghani, Nur Azurah. AU - Mohd Dali, Ahmad Hatta. PY - 2013/10. Y1 - 2013/10. N2 - Introduction: Human papillomavirus (HPV) is a major factor for cervical cancer. However, routine HPV vaccination to combat the disease is not widely available in most developing countries, and the uptake is poor. Lack of knowledge or awareness may be a factor. This study assessed the perception, knowledge and attitude of university students toward HPV vaccination and cervical cancer prevention. Methods and Materials: A cross-sectional survey among 826 students using a validated questionnaire was conducted at Universiti Kebangsaan Malaysia. The convenience sampling technique was used to recruits study subjects. The ...
PubMed journal article: Increased risk of oncogenic human papillomavirus infections and incident high-grade cervical intraepithelial neoplasia among smokers: experience from the Latin American screening study. Download Prime PubMed App to iPhone, iPad, or Android
TY - JOUR. T1 - Human papillomavirus prevalence and type distribution in male anogenital sites and semen. AU - Nielson, Carrie M.. AU - Flores, Roberto. AU - Harris, Robin B.. AU - Abrahamsen, Martha. AU - Papenfuss, Mary R.. AU - Dunne, Eileen F.. AU - Markowitz, Lauri E.. AU - Giuliano, Anna R.. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2007/6/1. Y1 - 2007/6/1. N2 - Background: Human papillomavirus (HPV) is sexually transmitted and causes cervical cancer. Although HPV can infect men and women, little is known about infection in men. Specifically, the prevalence of type-specific HPV infection and the distribution of infections by anogenital anatomic site in men are incompletely characterized. Methods: We tested 463 men ages 18 to 40 years for HPV at the glans/corona, penile shaft, scrotum, urethra, perianal area, anal canal, and in a semen sample. Eligible men acknowledged no history of genital warts and had sexual intercourse with a woman within the past year. ...
Cervarix (Prophylactic Human PapillomaVirus Vaccines) - Forecast and Market Analysis to 2022 is a new market research publication announced by Reportstack. The first prophylactic vaccine for immunization against human papillomavirus (HPV) became available in 2006. The global HPV vaccines market is now well established, yet vaccine coverage rates amongst the traditional target population of adolescent girls remain persistently low. Initially HPV vaccines were developed and marketed solely to protect against cervical cancer. In recent years the role of HPV in other cancers has been increasingly recognized which has facilitated a shift towards vaccinating a wider population, most significant has been the inclusion of males in routine vaccine recommendations in some countries. The current HPV vaccines market is dominated by one major player, Mercks Gardasil, with GlaxoSmithKlines (GSKs) HPV vaccine Cervarix providing the only competition. The introduction of Mercks nine-valent vaccine (V503) is ...
Data on the current burden of adenocarcinoma (ADC) and histology-specific human papillomavirus (HPV) type distribution are relevant to predict the future impact of prophylactic HPV vaccines. We estimate the proportion of ADC in invasive cervical cancer, the global number of cases of cervical ADC in 2015, the effect of cervical screening on ADC, the number of ADC cases attributable to high-risk HPV types -16, -18, -45, -31 and -33, and the potential impact of HPV vaccination using a variety of data sources including: GLOBOCAN 2008, Cancer Incidence in Five Continents (CI5) Volume IX, cervical screening data from the World Health Organization/Institut Català dOncologia Information Centre on HPV and cervical cancer, and published literature. ADC represents 9.4% of all ICC although its contribution varies greatly by country and region. The global crude incidence rate of cervical ADC in 2015 is estimated at 1.6 cases per 100,000 women, and the projected worldwide incidence of ADC in 2015 is 56,805 new
TY - JOUR. T1 - Hybrid capture 2 is as effective as PCR testing for high-risk human papillomavirus in head and neck cancers. AU - Hooper, Jody E.. AU - Hebert, Jessica F.. AU - Schilling, Amy. AU - Gross, Neil D.. AU - Schindler, Joshua S.. AU - Lagowski, James P.. AU - Kulesz-Martin, Molly. AU - Corless, Christopher L.. AU - Morgan, Terry K.. N1 - Publisher Copyright: © 2014 Wolters Kluwer Health, Inc. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 2015/4/22. Y1 - 2015/4/22. N2 - High-risk human papillomavirus (HPV) infection is a common cause of oropharyngeal squamous cell carcinoma, especially in young male nonsmokers. Accurately diagnosing HPV-associated oral cancers is important, because they have a better prognosis and may be treated differently than smoking-related oral carcinomas. Various methods have been validated to test for high-risk HPV in cervical tissue samples, and they are in routine clinical use to detect dysplasia before it progresses to invasive disease. ...
What is genital HPV infection?. Genital HPV is a common virus that is passed on through genital contact, most often during vaginal and anal sex. About 40 types of HPV can infect the genital areas of men and women.. While most HPV types cause no symptoms and go away on their own, some types can cause cervical cancer in women. These types also have been linked to other less common genital cancers- including cancers of the anus, vagina and vulva (area around the opening of the vagina).. Other types of HPV can cause warts in the genital areas of men and women, called genital warts.. How common is HPV? Approximately 20 million people are currently infected with HPV. At least 50 percent of sexually active men and women get genital HPV infection at some point in their lives. By age 50, at least 80 percent of women will have gotten genital HPV infection. About 6.2 million Americans get a new genital HPV infection each year.. How do I get a genital HPV infection? The types of HPV that infect the genital ...
The objectives of this study were to detect and determine the different genotypes of Human Papillomavirus (HPV) found in high-grade squamous preinvasive lesions of the uterine cervix of Cameroonian women. HPV genotyping was conducted on 37 endocervical secretions of women with high grade squamous intraepithelial lesions. HPV was found in 31 of the 37 women (83.8%); 9 different HPV genotypes were identified. The genotypes with high oncogenic potential were found in decreasing order of frequency as follows: 16, 18, 45, 33, 35 and 68. The frequency of strains found per patient ranged from 1 to 3. Genotypes 16 and 18 were single in 17 out of 31 patients. They were associated with other HPV genotypes in 4 out of 31 patients. In this study genotypes 16 and 18 are the most frequent genotypes encountered in high grade squamous preinvasive cervical lesions in Yaounde. This finding, if confirmed on a larger sample, portrays the potential effectiveness of HPV vaccines in the Cameroonian population as a preventive
Human papillomavirus vaccine effectiveness Dr. SWNS:South West Gardasil vaccine effectiveness Service 9 Gardasil gardasil vaccine efficacy effectiveness claims she has been left wheelchair-bound as a gardasil vaccine efficacy of a HPV jab she received at school But she claims a human papillomavirus HPV vaccine left her wheelchair-bound, shattering her dreams and leaving her constantly fatigued and her muscles wasting away.
As immunization programs for human papillomavirus (HPV) are implemented more widely around the world, interest is increasing in measuring their impact. One early measurable impact of HPV vaccine is on the prevalence of specific HPV types in a population. In low-resource settings, a potentially attractive strategy would be to monitor HPV prevalence using clinical cervical cancer screening test results to triage specimens for HPV typing. We assessed this approach in a nationally representative population of U.S. females aged 14-59 years. Using self-collected cervico-vaginal swab specimens from 4,150 women participating in the National Health and Nutrition Examination Survey during 2003-2006, we evaluated type-specific HPV prevalence detected by the Roche linear array (LA) research test on all specimens, compared with type-specific HPV prevalence detected by LA conducted only on specimens positive by the digene hybrid capture 2 (HC-2) clinical test. We calculated weighted prevalence estimates and ...
본 연구는 보건 계열 대학생의 HPV 지식과 HPV 관련 건강신념 및 감염 예방행위의도와의 관계를 확인하기 위하여 D시와 M시에서 2014년 6월 1일부터 6월 15일까지 보건계열대학생 264명을 대상으로 설문조사하였다. 수집된 자료는 SPSS 21.0을 이용하여 분석하였다. HPV 지식, 건강신념, 감염 예방행위의도는 대체로 낮은 점수를 보였고, HPV 지식과 건강신념간의 상관관계가 없게 나타났다. 그러나 HPV 예방접종 관련 건강신념이 높을수록 감염 예방행위의도는 높아졌다. 따라서 향후 HPV 관련 건강신념 및 감염 예방행위를 높일 수 있도록 HPV 지식을 포함한 구체적인 교육 프로그램 등의 방법이 필요할 것으로 생각된다. The purpose of this study was to identify the knowledge level, health beliefs related to HPV vaccination and HPV preventive behavior intention of human papilloma virus among health college student in Korea. A
TY - JOUR. T1 - Detection and Concentration of Plasma Aflatoxin Is Associated with Detection of Oncogenic Human Papillomavirus in Kenyan Women. AU - Zhang, Jianjun. AU - OrangO, Omenge. AU - Tonui, Philip. AU - Tong, Yan. AU - Maina, Titus. AU - Kiptoo, Stephen. AU - Muthoka, Katpen. AU - Groopman, John. AU - Smith, Joshua. AU - Madeen, Erin. AU - Ermel, Aaron. AU - Loehrer, Patrick. AU - Brown, Darron R.. PY - 2019/10/5. Y1 - 2019/10/5. N2 - Background: Cervical cancer is common in Kenyan women. Cofactors in addition to infection with oncogenic human papillomavirus (HPV) are likely to be important in causing cervical cancer, because only a small percentage of HPV-infected women will develop this malignancy. Kenyan women are exposed to dietary aflatoxin, a potent carcinogen and immunosuppressive agent, which may be such a cofactor. Methods: Demographics, behavioral data, plasma, and cervical swabs were collected from 88 human immunodeficiency virus-uninfected Kenyan women without cervical ...
Delory T., Ngo-Giang-Huong Nicole, Rangdaeng S., Chotivanich N., Limtrakul A., Putiyanun C., Suriyachai P., Matanasarawut W., Jarupanich T., Liampongsabuddhi P., Heard I., Jourdain Gonzague, Lallemant Marc, Le Coeur S., PapilloV study group (collab.). (2017). Human Papillomavirus infection and cervical lesions in HIV-1-infected women on antiretroviral treatment in Thailand. Journal of the International AIDS Society, 20 (Suppl. 5), 92-93. IAS Conference on HIV Science (IAS 2017) , 9., Paris (FRA), 2017/07/23-26. ISSN 1758-2652. ...
Human papillomavirus prevalence, viral load and pre-cancerous lesions of the cervix in women initiating highly active antiretroviral therapy in South Africa: a cross-sectional study. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
The vaginal microbiota plays a significant role in health and disease of the female reproductive tract. Next-generation sequencing techniques based upon the analysis of bacterial 16S rRNA genes permit in-depth study of vaginal microbial community structure to a level of detail not possible with standard culture-based microbiological techniques. The human papillomavirus (HPV) causes both cervical intraepithelial neoplasia (CIN) and cervical cancer. Although the virus is highly prevalent, only a small number of women have a persistent HPV infection and subsequently develop clinically significant disease. There is emerging evidence which leads us to conclude that increased diversity of vaginal microbiota combined with reduced relative abundance of Lactobacillus spp. is involved in HPV acquisition and persistence and the development of cervical precancer and cancer. In this review, we summarise the current literature and discuss potential mechanisms for the involvement of vaginal microbiota in the evolution
Overall, men were less willing to receive HPV vaccine when framed as preventing genital warts than when framed as also preventing several HPV-related cancers. This finding is similar to those from studies in which womens interest in HPV vaccine for themselves and for their adolescent daughters was higher when it was presented as preventing cervical cancer (10, 11). Although previous research indicated that including cervical cancer protection benefits for female partners did not affect HPV vaccine acceptability in males (12), we found that including cancer protection benefits for the males themselves resulted in greater acceptability of the vaccine. Furthermore, our experiment suggests that it does not matter which type of cancer was presented.. Consistent with other studies of HPV vaccine acceptability among males (12, 29, 30), men in our experiment were moderately willing to get vaccinated against HPV (31). Although gay and bisexual men were more willing to get HPV vaccine than their ...
Despite the demonstrated role of human Papillomavirus (HPV) in the etiology of cervical cancer and the strong evidence suggesting the importance of HPV in the development of oropharyngeal cancer, several aspects of the interrelationship between HPV infection in both body sites remain unknown, specifically in female human immunodeficiency virus (HIV)-positive (HIV+) patients. We aimed to assess the prevalence, distribution, and concordance of cervical and oral HPV in HIV+ women and matched HIV-negative (HIV-) controls in Brazil. Cervical and endocervical samples for cytological screening and HPV detection and oral samples were collected from 115 HIV+ women using highly active antiretroviral therapy (HAART) and 139 HIV-matched controls (HIV-) in Maringá City, Brazil. Risk factors were assessed using a standardized questionnaire, and the data regarding HIV infection were obtained from the patients medical records. HPV detection and typing were performed using the Kit Multiplex XGEN Multi HPV Chip HS12.
The Human Papillomavirus (HPV) is best known as the etiological agentof cervical cancer in women. Worldwide, cervical cancer is the secondmost common form of cancer in women. However, HPV can causemany more diseases including: genital warts, vulvar cancer, vaginalcancer, head and neck cancers, and anal cancer. The most common formof transmission is sexual contact. Unlike some sexually transmitteddiseases, penetrative sex is not necessary for HPV transmission; the viruscan spread easily through skin-skin contact. In fact, most adults will beexposed to HPV at some point during their life, but only a smallpercentage will develop cancer. Certain populations do have an increasedrisk of contracting an HPV infection: patients with humanimmunodeficiency virus (HIV) infection; people with multiple sexualpartners; and people that do not consistently use condoms; however,this link has only been shown in longitudinal studies (HumanPapillomavirus and HPV vaccines: Technical Information for PolicyMakers and ...
Learn more about Human Papillomavirus Vaccine at Grand Strand Medical Center What Is Human Papillomavirus?What Is the HPV Vaccine?Who Should Be Vaccinated and When?What...
Learn more about Human Papillomavirus Vaccine at TriStar Centennial What Is Human Papillomavirus?What Is the HPV Vaccine?Who Should Be Vaccinated and When?What Are...
article{9e26cd77-e33a-4061-b74b-6dd6a644862d, abstract = {BACKGROUND: Primary cervical screening with both human papillomavirus (HPV) DNA testing and cytological examination of cervical cells with a Pap test (cytology) has been evaluated in randomized clinical trials. Because the vast majority of women with positive cytology are also HPV DNA positive, screening strategies that use HPV DNA testing as the primary screening test may be more effective. METHODS: We used the database from the intervention arm (n = 6,257 women) of a population-based randomized trial of double screening with cytology and HPV DNA testing to evaluate the efficacy of 11 possible cervical screening strategies that are based on HPV DNA testing alone, cytology alone, and HPV DNA testing combined with cytology among women aged 32-38 years. The main outcome measures were sensitivity for detection of cervical intraepithelial neoplasia grade 3 or worse (CIN3+) within 6 months of enrollment or at colposcopy for women with a ...
Public Health Reports Volume 133, Issue 1, January/February 2018 http://phr.sagepub.com/content/current Research Authority of Pharmacists to Administer Human Papillomavirus Vaccine: Alignment of State Laws With Age-Level Recommendations One strategy to increase the uptake of human papillomavirus (HPV) vaccine among adolescents is through the use of pharmacists. Our objectives were to (1) use a publicly available…
TY - JOUR. T1 - Prevalence of cervical human papillomavirus in Taiwanese women. AU - Jeng, Cherng Jye. AU - Ko, Ma Lee. AU - Ling, Qing Dong. AU - Shen, Jenta. AU - Lin, Hui Wen. AU - Tzeng, Chii Ruey. AU - Ho, Chih Ming. AU - Chien, Tsai Yen. AU - Chen, Su Chee. PY - 2005/10. Y1 - 2005/10. N2 - Purpose: To define the prevalence rate of cervical human papilloma virus (HPV) using DNA oligonucleotide microarray and its correlation with risk factors in Taiwanese women in metropolitan Taipei. Methods: Thirteen hundred and twenty healthy women, aged 21-65 yr without history of cervical intraepithelial neoplasia (CIN) or carcinoma were included in this prospective study. Pap smear and HPV typing using oligonucleotide microarray were performed for each woman. They were given a standardized questionnaire to obtain information about the risk factors of cervical cancer in Taiwan. Results: The overall HPV positivity was 19.85% and multiple infections were found in 35.84% of the infected group, 7.92% of the ...
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes. However, the cytidine deaminase activity of APOBEC3 enzymes also induces somatic mutations in host genomes, which may drive cancer progression. Recent studies of human papillomavirus (HPV) infection and disease outcome highlight this duality. HPV infection is potently inhibited by one family member, APOBEC3A. Expression of APOBEC3A and APOBEC3B is highly elevated by the HPV oncoproteins E6 and E7 during persistent virus infection and disease progression. Furthermore, there is a high prevalence of APOBEC3A and APOBEC3B mutation signatures in HPV-associated cancers. These findings suggest that induction of an APOBEC3-mediated antiviral response during HPV infection may inadvertently contribute to cancer mutagenesis and virus evolution. Here, we discuss current understanding of APOBEC3A
TY - JOUR. T1 - Comparison of knowledge and attitudes toward human papillomavirus, HPV vaccine, pap tests, and cervical cancer between US and Peruvian women. AU - Han, Chi Son. AU - Ferris, Daron G.. AU - Waller, Jennifer. AU - Tharp, Philip. AU - Walter, Jessica. AU - Allmond, Lynn. PY - 2012/4. Y1 - 2012/4. N2 - OBJECTIVES: The purpose of this study was to determine and compare the knowledge and attitudes toward human papillomavirus (HPV), HPV vaccine, Pap tests, and cervical cancer among US and Peruvian women. MATERIALS AND METHODS: A convenience sample of 275 US women in Augusta, GA, and 702 Peruvian women living in or near Cusco, Peru, completed 22- or 21-item questionnaires, respectively. These questionnaires determined their knowledge about HPV, the HPV vaccine, Pap tests, and cervical cancer. Simple logistic regression was used to determine the relationship between location and language on the correct responses. Odds ratios (ORs) and 95% confidence intervals were calculated. RESULTS: US ...
Comprehensive postvaccination surveillance should not only consider reductions of vaccine type-specific infection and associated disease but should also assess any other potential effects of reductions of targeted infections. We assessed changes in nonvaccine HPV types to determine evidence of cross-protection for individual HPV types and to investigate the potential concern that reductions in certain HPV types after the introduction of HPV vaccination in a population could create a niche that enables other nonvaccine high-risk HPV types to become more common (i.e., type replacement). We found evidence of a reduction in the prevalence of HPV31 among girls and women ,19 years of age. Our main analysis showed increases in other nonvaccine HPV types (HPV39, HPV52, HPV53, HPV58, and HPV73), but these increases were inconsistent for the 2 age groups examined and the vaccines used.. A previous systematic review evaluated changes in high-risk HPV types combined and found evidence of a reduction in the ...
Background Cervical cancer is the fourth most common cancer affecting women worldwide. Since 2006, two Human Papillomavirus vaccines (HPVV ) have been licensed to protect women against the virus that causes cervical cancer. However, worldwide coverage remains unequal. Studies from the USA found strong evidence for differences in HPVV uptake by ethnicity and healthcare coverage. As the profile of ethnic groups and the healthcare system in the USA differ from countries in Europe where HPVV is free in most of the countries, we conducted a systematic review in order to analyze the determinants of HPVV uptake in Europe.Methods We performed a systematic Pubmed, Scopus and Science Direct search to find articles published from HPVV availability in European countries until April 2014. No age restriction was applied. We included all studies assessing factors associated with HPVV uptake. Uptake refers to either initiation and/or completion of the three dose vaccination program. Results Out of the 23 eligible
Cervical cancer ranks second among all cancers reported in Sri Lankan women. This study assessed the prevalence and type-distribution of human papillomavirus (HPV) among Sri Lankan women with invasive cervical cancer (ICC) and pre-cancerous lesions. 114 women aged 21 years and above, hospitalized in the National Cancer Institute, Sri Lanka with a diagnosis of ICC or cervical intraepithelial neoplasia (CIN) 2/3 were prospectively enrolled between October 2009 and September 2010 (110430/NCT01221987). The cervical biopsy or excision specimens collected during routine clinical procedures were subjected to histopathological review. DNA was extracted from samples with a confirmed histological diagnosis and was amplified using polymerase chain reaction and HPV DNA was detected using Enzyme Immuno Assay. HPV positive samples were typed using reverse hybridization Line Probe Assay. Of the cervical samples collected, 93.0% (106/114) had a histologically confirmed diagnosis of either ICC (98/106) or CIN 2/3 (8/106
Introduction In Japan, after receiving human papillomavirus vaccination, a significant number of adolescent girls experienced various symptoms, the vast majority of which have been ascribed to chronic...
Human papillomavirus vaccination in Oxford Medical clinic Kiev. European approach, professional specialists, budget-friendly prices, over 10 years of experience.
Immunological studies of cerebrospinal fluid from patients with CNS symptoms after human papillomavirus vaccination. Highlights. Abstract.
To our knowledge, this is the most comprehensive systematic review for a single country. Other HPV prevalence reviews included worldwide data and grouped all countries in North America together [27, 28, 65]. The past reviews included few Canadian studies, while data from 30 Canadian studies along with 21 companion reports were included here. Previous reviews focused on HPV prevalence among cervical cancer [27, 28, 65], HIV [82] or healthy individuals [83]. Our review includes data on the full spectrum of HR HPV infection, providing a more comprehensive understanding of the role of HPV genotypes in different manifestations of infection.. HPV prevalence data are required to provide information related to baseline HPV burden of disease when implementing vaccination programs. All of the included studies were either conducted prior to HPV vaccination or did not include vaccinated individuals. These data can be used to evaluate current HPV vaccination program in the future, including vaccine impact on ...
This multicenter study describes the type-specific prevalence of HPV infection in the general population from central and southern Italy, comparing the data with previously published Italian studies. Women aged from 25 to 65 who attended cervical cancer screening in five different Italian regions were tested for HPV infection with Hybrid Capture II (HCII) low and high risk probes. Women repeating Pap-test upon unsatisfactory or positive results, or as a post-treatment and post-colposcopy follow-up analysis, were excluded from our study. High risk (HR) HPV positive samples were typed using GP5+/GP6+ primed PCR, followed by Reverse Line Blot for 18 high/intermediate risk HPV types, while low risk (LR) HPV positive samples were tested with type specific primers for HPV6 and HPV11. 3817 women had a valid HCII test: 350 of them (9.2%) were positive for HR probes, 160 (4.2%) for LR probes, while 57 women were positive for both. Multiple infections were detected in 97 HR HPV positive women. The most common
Background : Major risk factors for invasive cervical cancer include infection with human papillomavirus HPV, infection with other sexually transmitted pathogens e.g., Chla-mydia trachomatis, and smoking. Since exposures to these risk factors can be related, the contribution of any single factor to cervical carcinogenesis has been difficult to...
CLINICAL INVESTIGATION (Araflt rma) DIAGNOSING HUMAN PAPILLOMAVIRUS AND HUMAN PAPILLOMAVIRUS TYPE 16 BY REALTIME PCR IN PATIENT UNDERGONE TO COLPOSCOPY AND SIGNIFICANCE OF THE DIAGNOSIS Sibel OZDAS 1,
The results of HPV detection in 550 cervical samples by cervical cytology were compared with the sequencing analysis and HPV genotyping 9G membrane test. The HPV genotyping 9G membrane test can efficiently identify and discriminate five HR-HPV genotypes. The 100% identical results of HPV genotyping 9G membrane tests with the sequencing results in 550 clinical samples ensure its wide clinical applicability. The simple handling steps and the portable scanning device make the HPV genotyping 9G membrane test applicable in point-of-care settings. Moreover, the HPV genotyping 9G membrane test allows one to obtain final results in 30 min at 25 °C by simply loading the hybridization and washing solution and scanning the membranes without any drying steps or special handling. The clinical sensitivity and specificity of the HPV genotyping 9G membrane test was found to be 100%, which is much higher than cervical cytology.
article{9f04c3bf-9d68-4d11-a5ff-d5704b4098d0, abstract = {Phase III trials have demonstrated the efficacy of human papillomavirus (HPV) vaccines in preventing transient and persistent high-risk (hr) HPV infection and precancerous lesions. A mathematical model of HPV type 16 infection and progression to cervical cancer, parameterised to represent the infection in Finland, was used to explore the optimal age at vaccination and pattern of vaccine introduction. In the long term, the annual proportion of cervical cancer cases prevented is much higher when early adolescents are targeted. Vaccinating against hr HPV generates greater long-term benefits if vaccine is delivered before the age at first sexual intercourse. However, vaccinating 12 year olds delays the predicted decrease in cervical cancer, compared to vaccinating older adolescents or young adults. Vaccinating males as well as females has more impact on the proportion of cases prevented when vaccinating at younger ages. Implementing catch-up ...
Accuracy and cost-effectiveness of cervical cancer screening by high-risk human papillomavirus DNA testing of self-collected vaginal samples.
1. Walboomers JM, Jacobs MV, Manos MM. et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189(1):12-9 2. Burd EM. Human papillomavirus and cervical cancer. Clin Microbiol Rev. 2003;16(1):1-17 3. Boyer SN, Wazer DE, Band V. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res. 1996;56(20):4620-4 4. Thomas M, Pim D, Banks L. The role of the E6-p53 interaction in the molecular pathogenesis of HPV. Oncogene. 1999;18(53):7690-700 5. Thierry F. Transcriptional regulation of the papillomavirus oncogenes by cellular and viral transcription factors in cervical carcinoma. Virology. 2009;384(2):375-9 6. Badaracco G, Venuti A, Sedati A. et al. HPV16 and HPV18 in genital tumors: significantly different levels of viral integration and correlation to tumor invasiveness. J Med Virol. 2002;67(4):574-82 7. Romanczuk H, Howley PM. Disruption of either the E1 or the E2 regulatory ...
Guidance for primary care trust human papillomavirus vaccine (HPV) uptake coordinators on how to determine the annual denominators and enter the vaccine uptake data.
Cervical cancer is a major public health problem in Malawi. The age-standardized incidence and mortality rates are estimated to be 75.9 and 49.8 per 100,000 population, respectively. The availability of the human papillomavirus (HPV) vaccine presents an opportunity to reduce the morbidity and mortality associated with cervical cancer. In 2013, the country introduced a school-class-based HPV vaccination pilot project in two districts. The aim of this study was to evaluate HPV vaccine coverage, lessons learnt and challenges identified during the first three years of implementation. This was an evaluation of the HPV vaccination project targeting adolescent girls aged 9-13 years conducted in Malawi from 2013 to 2016. We analysed programme data, supportive supervision reports and minutes of National HPV Task Force meetings to determine HPV vaccine coverage, reasons for partial or no vaccination and challenges. Administrative coverage was validated using a community-based coverage survey. A total of 26,766 in
2004). REPORT TO CONGRESS: Prevention of Genital Human Papillomavirus Infection. Human Papilloma Virus at Curlie. ... "Genital HPV Infection - Fact Sheet". Retrieved 16 November 2017. Syrjänen, Kari J.; Syrjänen, Stina M. (2000). Papillomavirus ... Genital warts are a sexually transmitted infection caused by certain types of human papillomavirus (HPV). They are generally ... Although 90% of HPV infections are cleared by the body within two years of infection, it is possible for infected cells to ...
"Human papillomavirus infections in laryngeal cancer". Head & Neck. Head Neck. 33 (4): 581-6. doi:10.1002/hed.21421. PMID ... Infections by some strains of Papillomaviridae carry some risk of laryngeal carcinoma. People with a history of head and neck ...
Human papilloma virus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus.[1] Available ... Module 19: Human papillomavirus infection" (PDF). WHO the Immunological Basis for Immunization Series. Archived (PDF) from the ... associated with infection by oncogenic human papillomavirus". Human Gene Therapy. 15 (5): 421-31. doi:10.1089/10430340460745757 ... "MVA E2 recombinant vaccine in the treatment of human papillomavirus infection in men presenting intraurethral flat condyloma: a ...
Human Papillomavirus infection: overview. In: Handbook on Human Papillomavirus: Prevalence, detection and management. Smith HB ... Viral infections in Obstetrics and Gynecology. Authors: Franco Borruto and Ciro Comparetto. In: Viral Infections: Causes, ... He is member of Eurogin and of the International Papillomavirus Society (IPVS). The last ten years were dedicated to promote ... The State-of-the-Art Therapeutic Human Papillomavirus Vaccine. Comparetto C, Borruto F. In: Horizons in Cancer Research, Volume ...
Squamous cell cancers of the tonsils are more strongly associated with human papillomavirus infection than are cancers of other ... link) Haddad, Robert I., MD (2007). "Human Papillomavirus Infection and Oropharyngeal Cancer" (PDF). Archived (PDF) from the ... "Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta- ... Hobbs, C.G.L.; Sterne, J.A.C.; Bailey, M.; Heyderman, R.S.; Birchall, M.A.; Thomas, S.J. (August 2006). "Human papillomavirus ...
"Cancer drug may help treat human papillomavirus infections". Retrieved 2018-11-30. Vorinostat bound to proteins in the PDB. ... belinostat and panobinostat might be repurposed to treat infections caused by human papillomavirus, or HPV. Trichostatin A " ...
She also studies the host cell responses to infection with the human papillomavirus in individuals who are immunodeficient, ... Stanley, MA (2012). "Epithelial cell responses to infection with human papillomavirus". Clin Microbiol Rev. 25 (2): 215-22. doi ... Stanley, MA; Sterling, JC (2014). "Host responses to infection with human papillomavirus". Curr Probl Dermatol. Current ... Stanley, MA (2012). "Genital human papillomavirus infections: current and prospective therapies". J Gen Virol. 93 (4): 681-91. ...
Ledger, William J. (July 2005). "Human Papillomavirus Infection in Women". Infectious Diseases in Clinical Practice. 13 (4): ... Gee, Rebekah E.; Shacter, Hannah E.; Long, Judith A. (October 2009). "Coverage of the Human Papillomavirus Vaccine by US and ...
Human papillomavirus (HPV) infection One of the Human papillomaviruses Human parainfluenza virus infection Human parainfluenza ... Infections associated with diseases. References[edit]. *^ Walsh TJ, Dixon DM (1996). Baron S, et al., eds. Spectrum of Mycoses ... Acinetobacter infections Acinetobacter baumannii Actinomycosis Actinomyces israelii, Actinomyces gerencseriae and ... Haemophilus influenzae infection Haemophilus influenzae Hand, foot and mouth disease (HFMD) Enteroviruses, mainly Coxsackie A ...
Her dissertation was titled Oropharyngeal cancer attributable to human papillomavirus 16 (HPV16) infection. Her doctoral ... D'Souza, Gypsyamber (2006). Oropharyngeal cancer attributable to human papillomavirus 16 (HPV16) infection (Thesis). OCLC ...
It is often thought to be a human papillomavirus (HPV) infection, but several studies have shown that the condition is not ... Fimiani M, Mazzatenta C, Biagioli M, Andreassi L (1993). "Vulvar squamous papillomatosis and human papillomavirus infection. A ... and the symptoms are often misdiagnosed as a yeast infection. Like yeast infections, there is discharge associated with ... Lack of evidence for human papillomavirus etiology". Arch Dermatol. 126 (12): 1594-8. doi:10.1001/archderm.1990.01670360058008 ...
Sinal SH, Woods CR (October 2005). "Human papillomavirus infections of the genital and respiratory tracts in young children". ... Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomavirus, bind and ... Münger K, Howley PM (November 2002). "Human papillomavirus immortalization and transformation functions". Virus Research. 89 (2 ... Greenblatt RJ (2005). "Human papillomaviruses: Diseases, diagnosis, and a possible vaccine". Clinical Microbiology Newsletter. ...
Human papillomavirus infection (HPV) causes more than 90% of cases; most people who have had HPV infections, however, do not ... Infection with some types of HPV is the greatest risk factor for cervical cancer, followed by smoking. HIV infection is also a ... Bosch FX, de Sanjosé S (2007). "The epidemiology of human papillomavirus infection and cervical cancer". Disease Markers. 23 (4 ... February 2013). "The role of co-factors in the progression from human papillomavirus infection to cervical cancer". Gynecologic ...
Infection with the human papillomavirus (HPV) can cause changes in the epithelium, which can lead to cancer of the cervix. ... Cervical cancer nearly always involves human papillomavirus (HPV) infection. HPV is a virus with numerous strains, several of ... HPV vaccines, developed in the early 21st century, reduce the risk of cervical cancer by preventing infections from the main ... As many as half of pregnant women having a gonorrheal infection of the cervix are asymptomatic. Other causes include overgrowth ...
... s are caused by infection with a type of human papillomavirus (HPV).[1] Factors that increase the risk include use of ... Warts are caused by the human papilloma virus (HPV). There are about 130 known types of human papilloma viruses.[8] HPV infects ... a b Human Papillomavirus Archived 2015-08-23 at the Wayback Machine.. Public Health Agency of Canada ... A range of types of wart have been identified, varying in shape and site affected, as well as the type of human papillomavirus ...
"Human Papillomavirus Infections and Upper Aero-Digestive Tract Cancers: The ARCAGE Study" (PDF). JNCI Journal of the National ... viral infections, and other lifestyle factors in cancer development. Renato Talamini was born in Vittorio Veneto, Italy, into a ...
INMEGEN studies how proteins are affected by the immune system in papillomavirus infection. The institution develops projects ...
4 November 1998). "Oral Cancer Risk in Relation to Sexual History and Evidence of Human Papillomavirus Infection". JNCI Journal ... Ault, KA (2006). "Epidemiology and Natural History of Human Papillomavirus Infections in the Female Genital tract". Infectious ... "Oral Human Papillomavirus (HPV) Infection in HPV-Positive Patients With Oropharyngeal Cancer and Their Partners". Journal of ... "Survival of squamous cell carcinoma of the head and neck in relation to human papillomavirus infection: Review and meta- ...
Cervical cancer can be caused by human papillomavirus (HPV) infection. AIM2 protein can recognise viral DNA in cytoplasm and ... HPV infection causes the upregulation of sirtuin 1 protein, which disrupts the transcription factor for AIM2, RelB. Knockdown ... In a healthy cell, caspase-1 activation helps to fight infection caused by Salmonella and Shigella by introducing cell death to ... Doitsh G, Greene WC (March 2016). "Dissecting How CD4 T Cells Are Lost During HIV Infection". Cell Host & Microbe. 19 (3): 280- ...
"Condom use and the risk of genital human papillomavirus infection in young women". N Engl J Med. 354 (25): 2645-54. doi:10.1056 ... a b c UNAIDS requests Pope Benedict XVI for support in efforts to stop new HIV infections in children; UNAIDS Feature Story; 11 ... The Pope pointed out that the use of a condom 'with the intention of reducing the risk of infection, can be a first step in a ... But it is not really the way to deal with the evil of HIV infection. That can really lie only in a humanization of sexuality. ...
Human papillomavirus. Human papillomavirus (HPV) is the most commonly transmitted sexually transmitted infection, affecting ... See: Larke et al. "Male circumcision and human papillomavirus infection in men: a systematic review and meta-analysis" (2011), ... Rehmeyer C, CJ (2011). "Male Circumcision and Human Papillomavirus Studies Reviewed by Infection Stage and Virus Type". J Am ... Larke N, Thomas SL, Dos Santos Silva I, Weiss HA (November 2011). "Male circumcision and human papillomavirus infection in men ...
Human papilloma virus (HPV) infection is necessary for the development of CIN, but not all with this infection develop cervical ... See also: Human papillomavirus infection § Cervical testing. The two screening methods available are the Pap smear and testing ... While infection with HPV is needed for development of CIN, most women with HPV infection do not develop high-grade ... The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is ...
"Cervical Human Papillomavirus (HPV) Infection and HPV Type 16 Antibodies in South African Women". Journal of Clinical ... Her area of expertise and what she is best known for is Human Papillomavirus and HIV Vaccines. Awarded a Chair in Vaccinology ... Her area of expertise is human papillomavirus, but is also known on an international level for her work in developing vaccines ... PMID 18240963.The goal of this publication is to identify the prevalence and risk factors associated with HPV Infection, and ...
Gunter, Jennifer (September 2003). "Genital and perianal warts: new treatment opportunities for human papillomavirus infection ... in situ hybridization analysis for human papillomavirus". Primary Care Update for OB/GYNS. Elsevier Science Inc. 5 (4): 152. ...
Human papillomavirus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus (HPV). ... Human Papillomavirus (HPV) Vaccination Program HPV (Human Papillomavirus) Human Papillomavirus (HPV-9) Vaccine Human ... 2007). "MVA E2 recombinant vaccine in the treatment of human papillomavirus infection in men presenting intraurethral flat ... World Health Organization (2011). The immunological basis for immunization series: module 19: human papillomavirus infection. ...
Lehr E, Hohl D, Huber M, Brown D (March 2004). "Infection with Human Papillomavirus alters expression of the small proline rich ...
It can also be associated with other types of infections, such as human papilloma virus. An association with chromosome 2 has ... This in turn affects the human immune systems ability to fight infection, in total there are 9 possible types of this condition ... Chronic mucocutaneous candidiasis is an immune disorder of T cells, it is characterized by chronic infections with Candida that ... The mechanism of the human immune system has it normally fighting in an infection (like Candida). Initially Th17 cells are made ...
"Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia". ... HPV infection of the vulva and vagina can cause genital warts or be asymptomatic. The cause of CIN is chronic infection of the ... While infection with HPV is needed for development of CIN, most women with HPV infection do not develop high-grade ... infection is necessary for the development of CIN, but not all with this infection develop cervical cancer. Many women with HPV ...
... s are caused by infection with a type of human papillomavirus (HPV). Factors that increase the risk include use of public ... Warts are caused by the human papilloma virus (HPV). There are about 130 known types of human papilloma viruses. HPV infects ... Human Papillomavirus Archived 2015-08-23 at the Wayback Machine. Public Health Agency of Canada Lipke MM (2006). "An ... Gardasil is designed to prevent infection with HPV types 16, 18, 6, and 11. HPV types 16 and 18 currently cause about 70% of ...
... acute HIV infection - Acute HIV Infection and Early Diseases Research Program (AIEDRP) - ADAP - ADC - adenopathy - adherence - ... human papilloma virus (HPV) - human T cell lymphotropic virus type I (HTLV-I) - human T cell lymphotropic virus type II (HTLV- ... ocular - off-label use - oncology - open-label trial - opportunistic infections - oral hairy leukoplakia (OHL) - organelle - ... breakthrough infection - Broadway Cares/Equity Fights AIDS - bronchoscopy - budding - buffalo hump - bugchasing and giftgiving ...
One area of particular interest is the study of human papilloma viruses (HPV) and their role in cervical cancers. Researchers ... Yersin looked for the germ responsible for the infection specifically in these plague-spots, tumors caused by the inflammation ... The discovery and use of sulfonamides in treating infections was another breakthrough. Some researchers won fame by discovering ... mistake by the Institute was ignoring a dissertation by Ernest Duchesne on the use of Penicillium glaucum to cure infections in ...
... may also arise in untreated diabetics due to the presence of glucose in their urine giving rise to infection in the ... September 2005). "Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease ...
Frenkl, Tara Lee, Potts, Jeannette (February 2008). "Sexually Transmitted Infections", Urologic Clinics of North America, 35 (1 ... Some sexually transmitted diseases are communicable between women, including human papillomavirus (HPV)-specifically genital ... HIV/AIDS Surveillance Report: Cases of HIV Infection and AIDS in the United States and Dependent Areas, 2006. Centers for ... Risser, Jan M.H., Risser, William L., Risser, Amanda (December 2008). "Epidemiology of Infections in Women", Infectious Disease ...
Palefsky J (2007). "Human papillomavirus infection in HIV-infected persons". Top HIV Med 15 (4): 130-3. பப்மெட் 17720998. ... Evan Secor Acute Schistosoma mansoni Infection Increases Susceptibility to Systemic SHIV Clade C Infection in Rhesus Macaques ... 117.0 117.1 Lawn SD (2004). "AIDS in Africa: the impact of coinfections on the pathogenesis of HIV-1 infection". J. Infect. Dis ... 35.0 35.1 Tang J, Kaslow RA (2003). "The impact of host genetics on HIV infection and disease progression in the era of highly ...
See also: Infection. Infections may be caused by bacteria, viruses, fungi, and parasites. The pathogen that causes the disease ... Human papillomavirus (HPV)[14]. Parasitic[edit]. *Malaria[11]. *Giardia lamblia[15]. *Toxoplasma gondii[16] ... Some infections can be dealt with by the body's own immune system, but more serious infections are treated with antimicrobial ... Bacterial infections are treated with antibacterials (often called antibiotics) whereas fungal and viral infections are treated ...
1960s - Discovered the first human slow virus disease, kuru, which is a degenerative, fatal infection of the central nervous ... and human papillomavirus (HPV).[7] ...
Viral infection. Papilloma virus has been proposed in several studies to have a potential role in prostate cancer, but as of ... In particular, infection with the sexually transmitted infections chlamydia, gonorrhea, or syphilis seems to increase risk.[42] ... Infection or inflammation of the prostate (prostatitis) may increase the chance for prostate cancer while another study shows ... Infections. In 2006, a previously unknown retrovirus, Xenotropic MuLV-related virus (XMRV), was associated with human prostate ...
... of people with gonorrheal infection also have chlamydial infection.[54] Infections of the throat can be especially problematic ... Human papillomavirus (HPV). *Genital warts (condyloma). *Hepatitis B (Hepatitis B virus). *Herpes simplex *HSV-1 & HSV-2 ... Both men and women with infections of the throat may experience a sore throat, though such infection does not produce symptoms ... The infection is usually spread from one person to another through vaginal, oral, or anal sex.[15][22] Men have a 20% risk of ...
A31.) Infection due to other mycobacteria *(A31.0) Pulmonary mycobacterial infection *Infection due to Mycobacterium avium ... B97.7) Papillomavirus as the cause of diseases classified to other chapters ... A80-B34 - Viral infections[संपादित करें]. (A80-A89) Viral infections of the central nervous system[संपादित करें]. *(A80.) Acute ... B34.) Viral infection of unspecified site. B35-B89 - Infections caused by fungi, protozoans, worms, and infestations[संपादित ...
2006). "Modeling the Sexual Transmissibility of Human Papillomavirus Infection using Stochastic Computer Simulation and ... Shukla N, Poles M (2004). "Hepatitis B virus infection: co-infection with hepatitis C virus, hepatitis D virus, and human ... 1.0 1.1 1.2 1.3 1.4 1.5 Sexually Transmitted Infection, "Ano ang STI?", Healthy Body STI/HIV-AIDS, NEWS, Foundation for ... Ang mga Sakit na naipapasa sa pakikipagtalik o mga sakit na nakukuha sa pakikipagtalik(Ingles: sexually transmitted infections ...
Human Papillomavirus නම් වෛරස් එන්නත නිෂ්පාදනය කර ඇත්තේ වෛරසයෙහි කැප්සිඩ ප්‍රෝටීන මගිනි. ... Artificial induction of immunity / Immunization: Vaccines, Vaccination, Infection, Inoculation (J07). Development. *Adjuvants ...
சருமத் தொற்று (Skin infection) என்பது மனிதர்களிடமும் பிற விலங்குகளிலும் தோலில் ஏற்படும் தொற்றுநோயாகும். இது தளர்வான இணைப்பு ... "The role of human papillomavirus in common skin conditions: current viewpoints and therapeutic options". Cutis 86 (5): suppl 1- ... In the WHO classification, it is noted that the infection classification "Excludes:... infective dermatitis...". See the WHO ... Skin inflammation due to skin infection is called "infective dermatitis". See the WHO classifications, op. cit. ...
Template:Protozoan infection navs(edit talk links history). *Template:Psych navs(edit talk links history) ({{Psychology navs ...
INO-3112 targets Human papillomavirus types 16 and 18.[52] In September, Valeant licensed Brodalumab from the company for up to ... "AstraZeneca To Acquire Infection Research Company Novexel And Expand Collaboration With Forest Laboratories". 23 December 2009 ...
Human papillomaviruses (HPVs) are frequently integrated into the cellular DNA in cervical cancers. We mapped by FISH five HPV18 ... "Apoptosis induced by Oropouche virus infection in HeLa cells is dependent on virus protein expression". Virus Research. 149 (1 ... Horizontal gene transfer from human papillomavirus 18 (HPV18) to human cervical cells created the HeLa genome, which is ... Hou, S.Y.; Wu, S.; Chiang, C. (2002). "Transcriptional activity among high and low risk human papillomavirus E2 proteins ...
The viral infection is limited to a localized area on the topmost layer of the superficial layer of the skin.[16] Once the ... Cervical cancer, vulvar cancer & Genital warts (condyloma), Penile cancer, Anal cancer (Human papillomavirus (HPV)) ... Molluscum contagiosum (MC), sometimes called water warts, is a viral infection of the skin that results in small, raised, pink ... For mild cases, over-the-counter wart medicines, such as salicylic acid may[21] shorten infection duration. Daily topical ...
Lorenz E (2007). "TLR2 and TLR4 expression during bacterial infections". Current Pharmaceutical Design. 12 (32): 4185-93. doi: ... TLR2 gene has been observed progressively downregulated in Human papillomavirus-positive neoplastic keratinocytes derived from ... These newly formed antibodies would arrive too late in an acute infection, however, so what we think of as "immunology" ... Borrello S, Nicolò C, Delogu G, Pandolfi F, Ria F (2011). "TLR2: a crossroads between infections and autoimmunity?". ...
Warts are caused by a virus called human papilloma virus or HPV. There are approximately 100 strains of human papilloma viruses ... a vaccine for HPV is designed to prevent infection with HPV types 16, 18, 6, and 11; it is claimed to prevent infections to ... ఇవి మానవ పాపిల్లోమా వైరస్ (Human Papilloma Virus-HPV) అనే వైరస్ వలక చర్మం మీద ఒక దగ్గర నుండి మరొక దగ్గరికి వ్యాపించే ప్రమాదం ... Syrjanen, K. HPV infections and lung cancer. Journal of Clinical Pathology 2002;55:885-891. ...
1926 - Johannes Andreas Grib Fibiger, Denmark, for his discovery that an infection could lead to cancer[20] ... 2008 - Harald zur Hausen, Germany, for finding the human papilloma viruses causing cervical cancer. Françoise Barré-Sinoussi ...
... of cancers are due to infections such as Helicobacter pylori, hepatitis B, hepatitis C, human papillomavirus infection, Epstein ... Vaccines have been developed that prevent infection by some carcinogenic viruses.[126] Human papillomavirus vaccine (Gardasil ... Journal of Infection in Developing Countries. 4 (5): 267-81. doi:10.3855/jidc.819. PMID 20539059. Archived from the original on ... Infection. Main article: Infectious causes of cancer. Worldwide approximately 18% of cancer deaths are related to infectious ...
Infection with the human papillomavirus (HPV) can cause changes in the epithelium, which can lead to cancer of the cervix. ... Cervical cancer nearly always involves human papillomavirus (HPV) infection.[42][43] HPV is a virus with numerous strains, ... "Human Papillomavirus (HPV) Vaccines". National Cancer Institute. Bethesda, MD. 29 December 2011. Retrieved 18 June 2014.. ... HPV vaccines, developed in the early 21st century, reduce the risk of cervical cancer by preventing infections from the main ...
2006). "Human papillomavirus link to circumcision is misleading (author's reply)". Cancer Epidemiol Biomarkers Prev. 15 (2): ... "Chlamydia trachomatis infection in female partners of circumcised and uncircumcised adult men". Am J Epidemiol. 162 (9): 907- ...
Other sexually transmitted infections. Syphilis (caused by infection with Treponema pallidum) is passed from person to person ... Genital human papillomavirus (HPV) is a common virus that most sexually active people in the U.S. will have at some time in ... of HIV infections are the result of men having sex with men.[28] However, in many developed countries, more HIV infections are ... Sexually transmitted infections. Main article: Sexually transmitted disease. A 2007 study reported that two large population ...
Human papillomavirus. Cervical cancer, Genital warts, anogenital cancers. HPV vaccine. Cervarix, Gardasil ... Frontiers in Cellular and Infection Microbiology. 2. doi:10.3389/fcimb.2012.00016.. ...
Viral infection[edit]. Viral induction of apoptosis occurs when one or several cells of a living organism are infected with a ... Liu Y, McKalip A, Herman B (May 2000). "Human papillomavirus type 16 E6 and HPV-16 E6/E7 sensitize human keratinocytes to ... The binding of nuclear receptors by glucocorticoids,[20] heat,[20] radiation,[20] nutrient deprivation,[20] viral infection,[20 ... Everett H, McFadden G (April 1999). "Apoptosis: an innate immune response to virus infection". Trends in Microbiology. 7 (4): ...
Cervical cancer, vulvar cancer & Genital warts (condyloma), Penile cancer, Anal cancer (Human papillomavirus (HPV)) ... "Global incidence and prevalence of selected curable sexually transmitted infections - 2008" (PDF)। who.int। পৃষ্ঠা 2, 19 ...
Human papillomavirus infection), Էպշտեյն-Բարր վիրուսը (Epstein-Barr virus), մարդու իմունային անբավարարության վիրուսը (ՄԻԱՎ, HIV ... Chronic bacterial and parasitic infections and cancer: a review» (PDF)։ Journal of Infection in Developing Countries 4 (5): 267 ... Օնկովիրուսների (քաղցկեղածին վիրուսների) թվին են պատկանում մարդու պապիլոմավիրուսը (Human papillomavirus), արգանդի վզիկի քաղցկեղը ...
Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs), are infections that are ... They also to a lesser extent protect against genital herpes, human papillomavirus (HPV), and syphilis.. The male condom is ... Some vaccinations may also decrease the risk of certain infections including hepatitis B and some types of HPV. Safer sex ... Promoting safe sex is now one of the aims of sex education and STI prevention, especially reducing new HIV infections. Safe sex ...
... human papillomavirus) (cervical carcinoma), ଏବସଟେନ ବାର ଭୂତାଣୁ (Epstein-Barr virus) - (ବି ସେଲ ଲିମ୍ଫୋପ୍ରୋଲିଫରେଟିଭ ରୋଗ) (B-cell ... "Chronic bacterial and parasitic infections and cancer: a review" (PDF). J Infect Dev Ctries. 4 (5): 267-81. doi:10.3855/jidc. ...
Human papillomavirus infection is an infection by human papillomavirus (HPV).[4] Most HPV infections cause no symptoms and ... An HPV infection is caused by human papillomavirus, a DNA virus from the papillomavirus family, of which over 170 types are ... HPV infection of the skin in the genital area is the most common sexually transmitted infection worldwide.[11] Such infections ... Skin infection ("cutaneous" infection) with HPV is very widespread.[19] Skin infections with HPV can cause noncancerous skin ...
Some HPV infections can lead to cancer. Most HPV infections (9 out of 10) go away by themselves within 2 years. But sometimes, ... HPV infections will last longer and can cause some cancers. HPV infections can cause cancers of the:. *Cervix, vagina, and ... HPV, or human papillomavirus, is a common virus that can cause cancers later in life. You can protect your child from these ... HPV infections are very common. Nearly everyone will get HPV at some point in their lives. ...
Cancers and Precancers Associated with Human Papillomavirus. Persistent infection with high-risk (oncogenic) types of HPV has a ... HIV Infection: Detection, Counseling, and Referral. *Diseases Characterized by Genital, Anal, or Perianal Ulcersplus icon * ... Persons with HIV infection or who are otherwise immunosuppressed are more likely to develop anogenital warts than those who do ... This medication is not recommended for persons with HIV infection, other immunocompromised conditions, or genital herpes ...
... infection is a common sexually transmitted infection (STI) caused by human papillomavirus. There are several different strains ... What is human papillomavirus infection?. Human papillomavirus (HPV) is a viral infection thats passed between people through ... Often, HPV infection doesnt cause any noticeable symptoms or health problems.. In fact, 90 percent. of HPV infections (9 out ... The virus that causes HPV infection is transmitted through skin-to-skin contact. Most people get a genital HPV infection ...
BERKELEY While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause ... And because the E2 protein is found only in papilloma viruses, a drug that blocks it shouldn t have side effects in humans. ... One study found that 75 percent of sexually active men and women under 50 have, or have had, an HPV infection, while 10,000 ... We re optimistic that this will work generally for many different genetic variants of human papilloma virus, though it s too ...
Y. M. Lai, Y. K. Soong, J. F. Lee, F.-P. Yang, H. Y. Huang, and C. C. Pao, "The effect of human papillomavirus infection on ... Human Papillomavirus Infection, Infertility, and Assisted Reproductive Outcomes. Nigel Pereira,1 Katherine M. Kucharczyk,1 ... The human papillomavirus (HPV) is a sexually transmitted infection common among men and women across all geographic and ... R. Yang, Y. Wang, J. Qiao, P. Liu, L. Geng, and Y.-L. Guo, "Does human papillomavirus infection do harm to in-vitro ...
OBJECTIVE: To assess the prevalence and potential risk factors associated with human papillomavirus (HPV) cervical infection ... Human papillomavirus cervical infection and associated risk factors in a region of Argentina with a high incidence of cervical ... OBJECTIVE: To assess the prevalence and potential risk factors associated with human papillomavirus (HPV) cervical infection ... RESULTS: Human papillomavirus DNA was found in 61% of samples analyzed (185/301). Samples with normal cytology had a 43% ...
The natural history of HPV infection was reviewed as part of a symposium on viral co-infections with HIV. Data from the New ... The natural history of HPV infection was reviewed as part of a symposium on viral co-infections with HIV. Data from the New ... While HIV-positive men have a higher rate of HPV infection and abnormal cells in the anal canal, the incidence of invasive anal ...
Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as ... Comprehensive control of human papillomavirus infections and related diseases.. Bosch FX1, Broker TR2, Forman D3, Moscicki AB4 ... Gains and challenges faced in the quest for comprehensive control of HPV infection and HPV-related cancers and other disease ... were attributable to HPV infection, with substantially higher incidence and mortality rates seen in developing versus developed ...
This mouse papillomavirus provides, for the first time, the opportunity to study papillomavirus infections in the context of a ... The model is a major step forward in the study of papillomavirus disease and pathology. In this review, we summarize studies ... and local host-restricted factors that may be involved in MmuPV1 infections and associated disease progression. ... and immunological mechanisms of MmuPV1 infections in both immunocompromised and immunocompetent hosts. ...
Panels Recommendations for Human Papillomavirus. Panels Recommendations. *HIV-infected individuals should use latex condoms ... Human Papillomavirus (Brief). The information in the brief version is excerpted directly from the full-text guidelines. The ... Dosing Recommendations for Prevention and Treatment of Human Papillomavirus (HPV). Indication. First Choice. Alternative. ... Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children. *Home ...
Human papillomavirus infection (HPV infection) is an infection caused by human papillomavirus (HPV), a DNA virus from the ... An HPV infection is caused by human papillomavirus, a DNA virus from the papillomavirus family. Over 170 types have been ... HPV infection of the skin in the genital area is the most common sexually transmitted infection worldwide. Such infections are ... Skin infection ("cutaneous" infection) with HPV is very widespread. Skin infections with HPV can cause noncancerous skin ...
7 in the journal Cell have found that not all infections are equal. An analysis of the HPV16 genome from 5,570 human cell and ... Human papillomavirus 16 accounts for about half of all cervical cancers, but researchers reporting Sept. ... Human papillomavirus 16 accounts for about half of all cervical cancers, but researchers reporting September 7 in the journal ... Nearly all cases of cervical cancer can be attributed to a persistent infection with one of a dozen high-risk HPV types, ...
The data suggest that HPV infection, especially oncogenic HPV types, is strongly associated with a non-Lactobacillus-dominant ... The microbial composition and its association with HPV infection, including 27 HPV types, were analyzed. Microbial alpha- ... infection is one of the most common sexually transmitted diseases. To define the HPV-associated microbial community among a ... Cheng, L., Norenhag, J., Hu, Y.O.O. et al. Vaginal microbiota and human papillomavirus infection among young Swedish women. npj ...
Also avail free - Human Papillomavirus Infection News Widget from Medindia ... Find latest news and research updates on Human Papillomavirus Infection. ... Human Papillomavirus Infection News. Human Papillomavirus Infection - Latest News and Research Updates Download Human ... Human papillomavirus (HPV) is the most common sexually transmitted infection and the cause of most cervical cancers and some ...
Recommendations for Preventing Human Papillomavirus Infections. Preventing First Episode of HPV Infection. Indications for HPV ... Oral human papillomavirus infection: differences in prevalence between sexes and concordance with genital human papillomavirus ... Human papillomavirus (HPV) infection is the major risk factor for development of cervical cancer,1,2 the fourth most common ... Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students. Am J Epidemiol. ...
Chlamydia (C.) trachomatis infection seems to also be associated with cervical cancer. We investigated whether C. trachomati … ... but most HPV infections will not persist and risk factors for HPV persistence are not well known. ... Human papillomavirus (HPV) persistence is the major cause of cervical cancer, ... Chlamydia trachomatis infection and persistence of human papillomavirus Int J Cancer. 2005 Aug 10;116(1):110-5. doi: 10.1002/ ...
Human Papillomavirus Infection - By: Brooke Covington by Brooke C , This newsletter was created with Smore, an online tool for ...
The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in ... Prevalence of human papillomavirus infection differs for men and women. Infectious Diseases Society of America ... The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in ... indicates a high prevalence of anal human papillomavirus (HPV) infection in all age groups of men who have sex with men. This ...
Determinants of genital human papillomavirus (HPV) persistence in 393 women initially cytologically normal were investigated by ... Persistence of type-specific human papillomavirus infection among cytologically normal women J Infect Dis. 1994 Feb;169(2):235- ... Although based on a prevalent cohort, these results are concordant with previous suggestions that HPV infection is usually ... Determinants of genital human papillomavirus (HPV) persistence in 393 women initially cytologically normal were investigated by ...
Human papillomavirus (HPV)-a small, double-stranded DNA virus-is the most common sexually transmitted infection in the United ... Prevention and Treatment of Human Papillomavirus Infections. Jessica A. Marketta, PharmD, RPh. Staff Pharmacist, Jacobi Medical ... Cutaneous infections include common, plantar, or flat warts, while mucosal infections include both genital and anogenital ... especially in those with concurrent HIV infection.2 Almost all cervical cancers are associated with persistent infection from ...
Molecular Diagnosis of Human Papillomavirus Infections , IntechOpen, Published on: 2013-04-30. Authors: Santiago Melón, Marta ... Infection by papillomaviruses requires that virus particles gain access to the epithelial basal layer and enter the dividing ... Molecular Diagnosis of Human Papillomavirus Infections. By Santiago Melón, Marta Alvarez-Argüelles and María de Oña DOI: ... Determination of genital human papillomavirus infection using consensus PCR. C.s. Herrington and J.O.D Mc Gee (ed.). Diagnostic ...
Human papillomavirus infections are very common and recurrent. Their presentation varies according to their site of affection. ... Suchibrata Das (August 7th 2020). Human Papillomavirus Infection: Management and Treatment, Human Papillomavirus, Rajamanickam ... Suchibrata Das (August 7th 2020). Human Papillomavirus Infection: Management and Treatment, Human Papillomavirus, Rajamanickam ... Gamma papillomavirus, Mu papillomavirus and Nu papillomavirus. HPVs infect epithelial cells in genital mucosa ( ...
Human papillomaviruses* The epithelial lining of the anogenital tract is the target for infection by a group of mucosotropic ... Human papillomavirus (HPV) infection is now recognized as the main cause of cervical cancer, the role of coexisting factors is ... Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia. J Natl Cancer Inst 1995; ... Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection. Eduardo L. Franco, Eliane Duarte- ...
Human papillomavirus infection and the multistage carcinogenesis of cervical cancer.. Schiffman M1, Wentzensen N. ... Human papillomavirus (HPV) infection and the multi-stage carcinogenesis of cervical cancer ... Human papillomavirus (HPV) infection and the multi-stage carcinogenesis of cervical cancer ... Human papillomavirus (HPV) infection and the multi-stage carcinogenesis of cervical cancer ...
High-risk human papillomavirus infections in breast cancer in Syrian women and their association with Id-1 expression: a tissue ... Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students. Am J Epidemiol. ... Prevalence and incidence of human papillomavirus infection in women in the USA: a systematic review. Int J STD AIDS. 2005;16: ... Breast cancer and human papillomavirus (HPV) infection: no evidence of a viral etiology in a group of Swiss women. Breast. 2007 ...
Human papillomavirus infection - Homo sapiens (human) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ... Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus. HPV infect mucoal and cutaneous epithelium resulting ...
Human papillomavirus infection - Mus musculus (mouse) [ Pathway menu , Pathway entry , Download KGML , Show description , Image ... Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus. HPV infect mucoal and cutaneous epithelium resulting ...
HIV Infections. Papillomavirus Infections. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases ... Oral human papillomavirus infection. HIV-infection. High-risk HPV viral load. Oral human papillomavirus infection in HIV- ... Papillomavirus Infections HIV Infections Procedure: Oral swabs for HPV-typing and high-risk HPV-determination ... Oral Human Papillomavirus Infection in HIV-infected Men. This study is currently recruiting participants. See Contacts and ...
HIV Infections. Papillomavirus Infections. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases ... Oral human papillomavirus infection. HIV-infection. High-risk HPV viral load. Oral human papillomavirus infection in HIV- ... Papillomavirus Infections HIV Infections Procedure: Oral swabs for HPV-typing and high-risk HPV-determination ... Oral Human Papillomavirus Infection in HIV-infected Men. The safety and scientific validity of this study is the responsibility ...
  • article{5c882bab-f058-4b9d-94d3-6746802bfb5e, abstract = {Human papillomavirus (HPV) persistence is the major cause of cervical cancer, but most HPV infections will not persist and risk factors for HPV persistence are not well known. (lu.se)
  • article{3e6f33c8-89ae-49a3-add4-62e2d8de646c, abstract = {Circumcision has been reported to protect against infection with human papillomavirus (HPV) in men, but results have been inconsistent. (lu.se)
  • Presented in part: European Research Organization on Genital Infection and Neoplasia Meeting, Paris, 23-26 April 2006 (abstract S11-2). (natap.org)
  • BIRMINGHAM, Ala. - Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs. (eurekalert.org)
  • Human papillomaviruses (HPVs) are a large and diverse group of viruses with 174 completely characterised types, with new HPV types being continuously found [ 1 ]. (intechopen.com)
  • All HPVs are believed to be capable of establishing long-term "latent" infections in small numbers of stem cells present in the skin. (wikipedia.org)
  • Infection with human papillomaviruses (HPV) is associated with the development of cervical cancer, but whether HPVs have a role in colorectal cancer remains controversial. (aacrjournals.org)
  • Integration of the viral genome into the cancer cell genome is characteristic of infection by these HPVs. (aacrjournals.org)
  • Although HPVs have long-recognized roles in tumorigenesis and cancers, our understanding of the molecular mechanisms by which these viruses interact with cells and usurp cellular processes to initiate infections and produce progeny virions is limited. (frontiersin.org)
  • Here, we provide a general overview of the current HPV infection paradigm, the epithelial differentiation-dependent HPV replicative cycle, and review the specifics of how HPVs usurp Rab-related functions during infectious entry. (frontiersin.org)
  • Human papillomaviruses (HPVs) are small, non-enveloped icosahedral viruses of 55 nm containing a circular, ≈8-kb double-stranded DNA genome condensed by cellular histones. (frontiersin.org)
  • Human papillomaviruses (HPVs) are also related to a subset of head and neck cancers (HNCs). (archives-ouvertes.fr)
  • Despite their importance as human pathogens, entry of human papillomaviruses (HPVs) into cells is poorly understood. (rupress.org)
  • In the last decade many studies have definitely shown that human papillomaviruses (HPVs) are the major cause of cervical carcinogenesis and, in the last few years, HPV testing has been proposed as a new and more powerful tool for cervical cancer screening. (springer.com)
  • Human papillomaviruses (HPVs) are one of the most common sexually transmitted infections in the world. (asm.org)
  • An HPV infection is caused by human papillomavirus , a DNA virus from the papillomavirus family, of which over 170 types are known. (wikipedia.org)
  • Patients with oropharynx cancer have a higher risk of death when not caused by human papillomavirus (HPV) than those whose tumors are HPV-positive, reports a new study. (medindia.net)
  • Human papillomavirus infection (HPV infection) is an infection caused by human papillomavirus (HPV), a DNA virus from the Papillomaviridae family. (wikipedia.org)
  • The broad distribution of high-risk HPV type 16 in women with normal cytology and colposcopy suggests that viral infection is an important determinant of regional cancer incidence. (mendeley.com)
  • The high effectiveness of prevention of intraepithelial uterine cervix changes connected with HPV infections of type 16, 18, 6 and 11 and a favourable safety profile - frequently shown in clinical tests - constitute a basis for recommending their use in programmes of active, primary cervical carcinoma prophylaxis in young teenage girls who have not started sexual relations yet [7]. (termedia.pl)
  • Estimate the prevalence of oral human papillomavirus (HPV) type 16, 18, 6, or 11 infection in young adult men. (knowcancer.com)
  • A letter to the editor is presented in response to the article "A Controlled Trial of a Human Papillomavirus Type 16 Vaccine" in the November 21, 2002 issue. (ebscohost.com)
  • In 1995, the World Health Organisation (WHO) identified human papillomavirus (HPV) type 16 and 18 as "at least a necessary factor" in the development of cervical cancer. (omicsonline.org)
  • Cell invasion by human papillomavirus type 16 (HPV16) is a complex process relying on multiple host cell factors. (asm.org)
  • Risk of Newly Detected Infections and Cervical Abnormalities in Women Seropositive for Naturally Acquired Human Papillomavirus Type 16/18 Antibodies: Analysis of the Control Arm of PATRICIA. (edu.au)
  • We found a very high prevalence of HPV infections among this cohort (86%), with more than one fourth of them (28%) positive for type 16. (biomedcentral.com)
  • HIV+ MSM show a very high rate of HPV infections in the anal canal and those with type 16 exhibited a multiplicity of associated types. (biomedcentral.com)
  • HPV, or human papillomavirus, is a common virus that can cause cancers later in life. (cdc.gov)
  • But sometimes, HPV infections will last longer and can cause some cancers. (cdc.gov)
  • Highly efficacious vaccines against HPV infection exist -- including the recently approved Gardasil 9, which immunizes against nine genotypes of HPV known to cause cervical, vulvar, vaginal and anal cancers, and genital warts. (eurekalert.org)
  • Human papillomavirus 16 accounts for about half of all cervical cancers, but researchers reporting September 7 in the journal Cell have found that not all infections are equal. (eurekalert.org)
  • 2 Almost all cervical cancers are associated with persistent infection from high-risk types of HPV. (uspharmacist.com)
  • Among men and women, cancers of the ano-genital tract and their precursor lesions have been strongly linked to infection with sexually transmited human papillomavirus. (intechopen.com)
  • In men, HPV infection has been strongly associated with anal cancer and is associated with approximately 85% of the anal squamous cell cancers that accur annually worldwide. (intechopen.com)
  • Likewise, approximately 50% of cancers of penis have been associtated to HPV infection [ 35 ]. (intechopen.com)
  • Given these conflicting data and the established complexity of the association between HPV with other cancers, a definitive relationship between human breast cancer and HPV infection has not been determined. (springer.com)
  • Viral infections contribute as a cause of 15-20% of all human cancers. (hindawi.com)
  • Viral infections contribute to 15-20% of all human cancers, whereby several viruses play considerable roles in the multistage development of malignant cancers. (hindawi.com)
  • Also, according to the Canadian Cancer Society, HPV infection is associated with about 80-90% of anal cancers, 40% of vaginal and vulvar cancers, 40-50% of penile cancers and 25-35% of mouth and throat cancers. (drpaul.com)
  • Because of the association between this virus and cancer, it is logical to assume that if we can prevent the infection in the first place, we can prevent the cancers these viruses cause. (drpaul.com)
  • Papillomaviruses (PVs) were the first viruses recognized to cause tumors and cancers in mammalian hosts by Shope, nearly a century ago ( Shope and Hurst, 1933 ). (frontiersin.org)
  • Despite effective vaccines and screening, HPV infection and morbidity remain a significant worldwide burden, with HPV infections and HPV-related cancers expected increase through 2040. (frontiersin.org)
  • No role for human papillomavirus infection in oral cancers in a region in southern India. (archives-ouvertes.fr)
  • Despite a recent focus on the prevention of infection for certain HPV types, a large population remains at risk of HPV-related cancers. (perssupport.nl)
  • HPV-related cancers, which occur when a chronic infection of some HPV types cause changes to infected cells, are responsible for over 650 thousand cases globally[1] each year. (perssupport.nl)
  • HPV infection is more common among men than women, leading to an increased risk for men of head and neck cancers, a US study suggests. (affleap.com)
  • Jessica Harris, health information manager at Cancer Research UK, said: "As we learn how common HPV infections in the mouth are, and how they are passed on, we can understand more about who is most at risk and how people can reduce the risk of HPV-related cancers. (affleap.com)
  • although the virus alone may not be sufficient to cause cancer [ 4 ], virtually all cervical cancers are associated with persistent infection with one of the high-risk types of HPV. (biomedcentral.com)
  • Infection of mucosal epithelium by oncogenic HPV genotypes can lead to cervical, anogenital, and other head and neck cancers. (asm.org)
  • The data suggest that HPV infection, especially oncogenic HPV types, is strongly associated with a non- Lactobacillus- dominant vaginal microbiota, regardless of age and vaccination status. (nature.com)
  • 12,19,20 Persistence of oncogenic HPV infection is a necessary step in HPV-related cervical tumorigenesis, 1,21,22 although it appears insufficient for final cell transformation. (nih.gov)
  • We conclude that persistence of oncogenic HPV infections is more likely among women with a previous C. trachomatis infection. (nih.gov)
  • Current research has focused on the determinants of infection with oncogenic HPV types, the assessment of prophylactic and therapeutic vaccines and the development of screening strategies incorporating HPV testing and other methods as adjunct to cytology. (cmaj.ca)
  • Infection by oncogenic viruses can promote different stages of carcinogenesis. (hindawi.com)
  • There have been many studies worldwide on the epidemiology of HPV infection and oncogenic properties due to different HPV genotypes. (hindawi.com)
  • The rates of the most well-known oncogenic types (human papillomavirus 16 and/or 18) also show this increased risk. (scielo.br)
  • In addition to the oncogenic human papillomavirus (HPV), several cofactors are needed in cervical carcinogenesis, but whether the HPV covariates associated with incident (i) CIN1 are different from those of incident (ii) CIN2 and (iii) CIN3 needs further assessment. (unboundmedicine.com)
  • Known as the Ludwig-McGill cohort study, the epidemiological investigation focuses on persistent infection with oncogenic HPV types as the precursor event leading to cervical neoplasia. (scielosp.org)
  • BERKELEY While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected and at constant risk of genital warts and cancer. (webwire.com)
  • Human papillomavirus (HPV) persistence is the major cause of cervical cancer, but most HPV infections will not persist and risk factors for HPV persistence are not well known. (nih.gov)
  • Human papillomavirus (HPV) infection is now recognized as the main cause of cervical cancer, the role of coexisting factors is better understood, a new cytology reporting terminology has improved diagnosis and management of precursor lesions, and specific treatment protocols have increased survival among patients with early or advanced disease. (cmaj.ca)
  • Human papillomavirus (HPV) infection is a necessary cause of cervical cancer. (springer.com)
  • Among sexually transmitted infections (STIs), only HPV infection is known to be a major cause of cervical cancer. (medsci.org)
  • Although few would dispute nowadays that human papillomavirus (HPV) infection is the central cause of cervical cancer, most of the epidemiologic data have come from retrospective, case-control studies (1), which do not provide information on the dynamics of cumulative exposure to cervical HPV infection. (scielosp.org)
  • OBJECTIVE: To assess the prevalence and potential risk factors associated with human papillomavirus (HPV) cervical infection among women residing in a region of northeastern Argentina with a high incidence of cervical cancer. (mendeley.com)
  • [3] Risk factors for persistent HPV infections include early age of first sexual intercourse , multiple partners, smoking, and poor immune function . (wikipedia.org)
  • Nearly all cases of cervical cancer can be attributed to a persistent infection with one of a dozen high-risk HPV types, especially HPV16. (eurekalert.org)
  • Although based on a prevalent cohort, these results are concordant with previous suggestions that HPV infection is usually transient and that cervical cancer may arise from within the subset of women with persistent HPV infection. (nih.gov)
  • This short review outlines our understanding of cervical cancer precursors, concentrating on the central etiologic role of persistent human papillomavirus infection. (nih.gov)
  • Persistent, oral, high-risk HPV infection for children was children born to HPV-positive mothers have a higher associated with oral HPV carriage of the mother at birth risk of becoming HPV positive ( 9 - 14 ). (cdc.gov)
  • However, in some women the immune response is insufficient to eliminate the virus, resulting in a persistent, long-term infection that may progress to a malignant lesion. (dovepress.com)
  • The excess risks for multiple-type infections remained after exclusion of women infected with HPV-16, with high-risk HPV types, or persistent infections, particularly for any-grade SIL. (aacrjournals.org)
  • Evidence from cohort studies also indicates that risk of cervical neoplasia is greatest among women who develop persistent HR-HPV infections ( 5 - 7 ). (aacrjournals.org)
  • Objective To investigate frequency and risk factors for prevalent, incident, and persistent carcinogenic human papillomavirus (HPV) in young women before the introduction of immunisation against HPV types 16 and 18 for schoolgirls. (bmj.com)
  • 1 Persistent infection with a carcinogenic human papillomavirus (HPV) is a prerequisite for cervical cancer, 2 and around 20% of women with one year persistence of HPV infection in the cervix will develop cervical intraepithelial neoplasia or cervical cancer in the next five years. (bmj.com)
  • Prevention of persistent cervical HPV-16 and -18 infections and related CIN has been shown with monovalent or bivalent HPV virus-like-particle (VLP) vaccines [5-7]. (natap.org)
  • In a cohort of this population persistent infection was compared with cytological, colposcopic, and histological lesions. (ecancer.org)
  • The follow-up study revealed a low percentage of persistent infection, and a high frequency of negativity for viral infection, high regression of cytological and colposcopic lesions, a low cumulative and incidence rate similar to that reported by other Latin American countries and higher than the European countries. (ecancer.org)
  • Human papillomavirus and the epidemiology of head and neck cancer. (medlineplus.gov)
  • The current review appraises the recent medical literature pertaining to the epidemiology, immunobiology, and impact of HPV infection on normal reproductive function. (hindawi.com)
  • While HPV vaccination will totally change the epidemiology of HPV infection, vaccinating older women has a very limited role. (springer.com)
  • However, little is known about the epidemiology of oral HPV infection. (cdc.gov)
  • This proposal is the first unified initiative of nine European institutions in Northern and Southern Europe and one in Australia, each disposing of a long-standing expertise in the field of papillomavirus research and/or epidemiology of skin cancer to study the role of HPV in skin cancer oncogenesis. (europa.eu)
  • Although much is known about the molecular epidemiology of genital HPV infection in women, very little is known about the probability of reinfection with HPV, especially with the same type. (aacrjournals.org)
  • [1] In some people, an HPV infection persists and results in warts or precancerous lesions . (wikipedia.org)
  • Biopsy might also be indicated in the following circumstances, particularly if the patient is immunocompromised (including those with HIV infection): the diagnosis is uncertain, the lesions do not respond to standard therapy, or the disease worsens during therapy. (cdc.gov)
  • 34 HIV infection and low CD4 cell count also have been consistently and strongly associated with HPV infection itself and with precancerous cervical lesions, including low-grade cervical intraepithelial neoplasia (CIN), and the precursor to cervical cancer, CIN 3. (nih.gov)
  • HPV infection is associated with a variety of clinical conditions, ranging from benign lesions to cervical cancer. (dovepress.com)
  • These findings have implications for the management of cervical lesions and prediction of the outcome of HPV infections. (aacrjournals.org)
  • Of these, some studies have suggested a possible role for multiple HPV types in the development or progression of cervical neoplasia ( 8 , 11 , 15 - 20 ), whereas others have shown that the risk of cervical precancerous lesions or invasive cancer in women infected with multiple HPV types was no greater than that in those with single-type infections ( 9 , 12 , 21 - 25 ). (aacrjournals.org)
  • The women included in this study were enrolled into the Ludwig-McGill cohort, an ongoing longitudinal investigation of the natural history of HPV infection and precursor lesions of cervical cancer. (aacrjournals.org)
  • Many HPV infections are inapparent, but certain HPV types cause symptomatic hyper-proliferative lesions (i.e., tumors, warts, or papillomas). (frontiersin.org)
  • The prevalences of oral or oropharyngeal human papillomavirus infections were respectively 6.2%, 44.6%, 44.4%, 27.4%, 38.5% and 11.9% for healthy people, those with benign oral lesions, pre-malignant lesions, oral or oropharyngeal squamous cell carcinoma, risk groups (patients with genital human papillomavirus lesions or infected partners) and immunocompromised patients. (scielo.br)
  • The risk of human papillomavirus infection was estimated for each subgroup and it was evident that, when compared to the healthy population, the risk of human papillomavirus infection was approximately 1.5-9.0 times higher, especially in patients with an immunodeficiency, oral lesions and squamous cell carcinoma. (scielo.br)
  • Other groups, such as at-risk patients or their partners, immunocompromised patients, people with oral lesions and patients with oral cavity or oropharyngeal squamous cell carcinoma have a high risk of human papillomavirus infection. (scielo.br)
  • 1 HPV infection is associated with several proliferative, wartlike lesions of the skin and mucosae. (scielo.org.za)
  • Due to the common occurrence of benign HPV-induced oral lesions, it is important for the oral health care worker to have a sound knowledge of their clinical manifestations and roles in the health of a patient as well as the current protocol for prevention of infection. (scielo.org.za)
  • The clinical features of HPV-associated lesions are dependent on the subtype of HPV as well as the site of infection. (scielo.org.za)
  • HPV infection usually occurs via direct contact and is thus frequently associated with sexual transmission in anogenital lesions. (scielo.org.za)
  • Human papillomavirus infection in actinic keratosis and bowen's disease: comparative study with expression of cell-cycle regulatory proteins p21(Waf1/Cip1), p53, PCNA, Ki-67, and Bcl-2 in positive and negative lesions. (biomedsearch.com)
  • We examined the presence of human papillomavirus (HPV) DNA in tissues of premalignant skin lesions, i.e., actinic keratosis (n = 13) and Bowen's disease (n = 62), taken from 69 Japanese immunocompetent and renal transplant recipient patients. (biomedsearch.com)
  • Immunohistochemistry for p21(Waf1/Cip1), p53, proliferating cell nuclear antigen (PCNA), Ki-67, and Bcl-2 revealed that there was no significant difference in the cell proliferation activity between HPV-positive and HPV-negative lesions, suggesting that HPV infection alone does not induce cell proliferation in those lesions. (biomedsearch.com)
  • Cervical lesions have been associated with infection by high-risk human papilloma virus (high-risk HPV). (ecancer.org)
  • Fifty-seven patients were evaluated 15 months after the base study, with initial prevalence of morbidity 49.12% (28/57) and at the end 10.53% (6/57), showing in 89.29% (25/28) negative for HR-HPV infection, 10.34% (3/28) showed persistence of infection, 17.54% (10/57) presented cytological alterations, with 80% of positivity for HPV, and a regression of 100% (10/10) of the previously identified lesions. (ecancer.org)
  • Prevalence of and risks for cervical human papillomavirus infection and squamous intraepithelial lesions in adolescent girls: impact of infection with human immunodeficiency virus. (harvard.edu)
  • Data on HPV infection and histological and cytological lesions of the cervix were obtained and analyzed. (biomedcentral.com)
  • Considering the public health and economic importance of cervical cancer and the current widespread interest in the development of HPV vaccines and in using HPV testing to augment existing cytology screening programs, there is a clear need for prospective, long-term multidisciplinary studies of the natural history of HPV infection as it progresses to preinvasive cervical lesions. (scielosp.org)
  • Detection of human papillomavirus infection by non-isotopic in situ hybridisation in condylomatous and CIN lesions. (bmj.com)
  • AIMS--To study the value of non-isotopic in situ hybridisation (NISH) in detecting human papillomavirus (HPV) infection in female genital lesions positive for the virus by conventional histology but negative by filter DNA hybridisation. (bmj.com)
  • Human papillomavirus (HPV) is a viral infection that's passed between people through skin-to-skin contact. (healthline.com)
  • Because they built the peptide to enter cells easily, the peptide has potential as a topical treatment for the viral infection. (webwire.com)
  • Many studies have suggested a possible link between breast cancer pathogenesis and viral infection, particularly mouse mammary tumour virus, simian virus 40, Epstein-Barr virus, and human papillomavirus (HPV). (springer.com)
  • The goal of this study was to use a cohort study with repeated measurements of viral infection and lesion outcomes to investigate the role of multiple HPV types in the development of cervical neoplasia. (aacrjournals.org)
  • HPV carries a significant disease burden, which can be addressed by intercepting disease progression and treating the viral infection," says Johan Van Hoof, M.D., Global Head, Infectious Diseases and Vaccines, Janssen. (perssupport.nl)
  • Bacitracin caused an unusual time-dependent opposing effect on viral infection. (asm.org)
  • The investigation will attempt to understand attributes of the natural history of viral infection that may be instrumental to the design of primary and secondary strategies for preventing cervical cancer. (scielosp.org)
  • This article reports on a large longitudinal study, begun in 1993, of the natural history of human papillomavirus (HPV) infection and cervical neoplasia in a population of low-income women in São Paulo, Brazil, a city with one of the highest risks worldwide for cervical cancer. (scielosp.org)
  • [19] Skin infections with HPV can cause noncancerous skin growths called warts (verrucae). (wikipedia.org)
  • HPV types 16, 18, 31, 33, and 35 also are occasionally identified in anogenital warts (usually as infections with HPV 6 or 11) and can be associated with foci of high-grade squamous intraepithelial lesion (HSIL), particularly among persons who have HIV infection. (cdc.gov)
  • Cutaneous infections include common, plantar, or flat warts, while mucosal infections include both genital and anogenital diseases. (uspharmacist.com)
  • Human Papillomavirus (HPV) is arguably the most common sexually transmitted agent worldwide, either in its clinical (genital warts) or subclinical presentation in men and women. (intechopen.com)
  • Although these latent infections may never be fully eradicated, immunological control is thought to block the appearance of symptoms such as warts. (wikipedia.org)
  • HPV infection, one of the most common sexually transmitted diseases, is now recognized as the causative agent of both genital warts and cervical dysplasia, the two major clinical manifestations of HPV. (infectioncontroltoday.com)
  • Human papillomavirus (HPV) has been identified the etiologic agent of warts, cervical intraepithelial neoplasia (CIN), and cervical cancer. (medsci.org)
  • In our study we have investigated the effect of HPV infection on the balance between oxidants and antioxidants in patients with genital warts. (medworm.com)
  • Infections with low-risk types, such as HPV types 6 and 11, can cause benign or low grade changes in cervical cells, genital warts, and recurrent respiratory papillomatosis. (biomedcentral.com)
  • Genital warts are a sexually transmitted infection caused by certain types of human papillomavirus (HPV). (wikipedia.org)
  • Warts are the most easily recognized symptom of genital HPV infection. (wikipedia.org)
  • In most cases, there are no symptoms of HPV infection other than the warts themselves. (wikipedia.org)
  • In individuals with a history of previous HPV infection, the appearance of new warts may be either from a new exposure to HPV, or from a recurrence of the previous infection. (wikipedia.org)
  • Reporting two or more sexual partners in the previous year and concurrent Chlamydia trachomatis or bacterial vaginosis were independent risk factors for prevalent vaginal HPV infection. (bmj.com)
  • Conclusion In the first UK cohort study of carcinogenic HPV in young women in the community, multiple sexual partners was an independent predictor of both prevalent and incident infection. (bmj.com)
  • Our results suggest that colorectal HPV infection is common in patients with colorectal cancer, albeit at a low DNA copy number, with HPV16 being the most prevalent type. (aacrjournals.org)
  • Although anal high-risk human papillomavirus (HR-HPV) infection and anal cytological abnormalities are highly prevalent among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM), there are insufficient data on these abnormalities among HIV-infected heterosexual men (HSM) and women. (dovepress.com)
  • One of the most prevalent STIs is the Human Papillomavirus (HPV). (medworm.com)
  • With over 300 million estimated infections among men and women annually, HPV is the most prevalent sexually transmitted disease in the world. (perssupport.nl)
  • Roche Linear Array HPV Genotyping Test® was used to characterize prevalent HPV and log-binomial regression models were used to examine the association between potential correlates and the prevalence of HPV infection. (biomedcentral.com)
  • HR-HPV infection was more prevalent in younger women, cohabiting, nulliparae, smokers, having had over three sexual partners and early age of sexual debut. (bibsys.no)
  • Human Papillomavirus (HPV) infections are highly prevalent among HIV+ MSM and recent studies have shown high rates of HPV-associated anal intraepithelial neoplasia (AIN) and anal cancer among this population. (biomedcentral.com)
  • Epithelium of anogenital sites -- the cervix, penis and anus -- or epithelium of the mouth and throat are sites of HPV infection. (eurekalert.org)
  • In this context, HPV-associated anogenital malignancies occur with high frequency in patients with HIV-infection. (clinicaltrials.gov)
  • 2007) Risk factors for anogenital human papillomavirus infection in men. (scirp.org)
  • Human Papillomaviruses and Anogenital Cancer. (ebscohost.com)
  • A letter to the editor is presented concerning human papillomavirus and anogenital cancer. (ebscohost.com)
  • The type attribution is based on the hierarchical attribution model for carcinogenic genotypes present in multiple infections. (nih.gov)
  • HPV vaccines are very effective at preventing infection and diseases related to the vaccine-specific genotypes in women with no evidence of past or current HPV infection. (hindawi.com)
  • Background: Besides an established role for certain human papillomavirus (HPV) genotypes in the etiology of cervical cancer, little is known about the influence of multiple-type HPV infections on cervical lesion risk. (aacrjournals.org)
  • Of these women, 13 (65%) had redetected infection with HPV 16 or 18, and nine (45%) with non-vaccine carcinogenic HPV genotypes. (bmj.com)
  • Infection with non-vaccine carcinogenic genotypes was common. (bmj.com)
  • Transmission of high-risk human papillomavirus (HPV) between parents and infant: a prospective study of HPV in families in Finland. (springer.com)
  • Thus, this prospective study mainly focuses on the incidence and prevalence of oral HPV-infection, spectrum of HPV-types, and oral high-risk HPV viral load in HIV-positive men. (clinicaltrials.gov)
  • However, infections by the high-risk HPV types persist which then increase the risk of progression to cervical cancer [ 3 ]. (hindawi.com)
  • This risk was even higher (45%) when only high-risk HPV infections were considered ( 6 ). (cdc.gov)
  • DNA viruses like high risk HPV strains can produce substantial number of variants owing to factors like large population sizes, long infection time and hypermutation of the epitopes which can lead to significant evolution of virus within the host. (omicsonline.org)
  • Cervical infection with high-risk HPV typically lasts from 12 to 18 months and in most cases is cleared spontaneously. (dovepress.com)
  • DNA was extracted from 689 fresh-frozen UBC tissues and screened for the presence of high-risk human papillomavirus (HPV) types 16 and 18 and BKV/JCV genomic DNA by qPCR. (urotoday.com)
  • The main objective of this study was to measure oral HPV viral load for the subset of oral rinse samples (ORS) that were positive for high-risk or probably high-risk HPV types from the NHANES 2009-2010 study entitled Prevalence of Oral HPV Infections in the United States Population. (cdc.gov)
  • Oral rinse samples that were positive for high-risk HPV by use of Roche Linear Array from NHANES 09-10, Prevalence of Oral HPV Infections in the United States Population. (cdc.gov)
  • Large epidemiological and prospective studies conducted in various countries have shown that the risk of developing cervical cancer is strongly associated with the presence and persistence of high-risk genital papillomavirus types (Bosh & San José 2003). (scielo.br)
  • Because few population-based studies have investigated the prevalence of type-specific infection in relation to cervical disease, we studied a high-risk population, estimating the prevalence of HPV infection and the risk associated with various HPV types. (uni-bonn.de)
  • In conclusion, the present work shows a high frequency of infection by high-risk HPV, with predominance of HPV18 and 16 and in general for multiple infections. (ecancer.org)
  • While sociodemographic predictors of cervical cancer (CC) are well understood, predictors of high-risk (HR) human papillomavirus (HPV) infection have not been fully elucidated. (bibsys.no)
  • FSWs are at a substantially high risk of HPV infection and cervical dysplasia development as compared with healthy control subjects in Shenyang, China. (biomedcentral.com)
  • High-risk HPV infection was associated with current smoking and formal education, while trichomoniasis was associated with reproductive age and high cast/ ethnicity. (bibsys.no)
  • Acquisition of high-risk human papillomavirus infection in a population-based cohort of Danish women. (arctichealth.org)
  • To better understand the natural history of HPV, we assessed the incidence of type-specific HPV infection and examined risk factors for acquisition of high-risk (HR) HPV infection in Danish women. (arctichealth.org)
  • OBJECTIVES: This study was conducted to determine the prevalence of and associated risk factors for infection with oral high-risk human papillomavirus (HR-HPV) in adult participants within England, and to explore any association with oral mucosal buccal epithelial cell and whole blood folate concentration. (whiterose.ac.uk)
  • We investigated whether C. trachomatis infection is a risk factor for HPV persistence. (nih.gov)
  • Determinants of genital human papillomavirus (HPV) persistence in 393 women initially cytologically normal were investigated by testing them for HPV DNA twice over a median interval of 14.9 months. (nih.gov)
  • As a unique feature of our cohort study, persistence of HPV infection is monitored by molecular variant analysis (2) and measurement of viral burden (3), which together provide a much finer level of detail than simple HPV testing and may improve the prediction of the likelihood of lesion progression. (scielosp.org)
  • The Department of Health and Human Services (HHS) Panel on the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children (or the Panel) is accepting nominations for scientific/clinical members with expertise in pediatric HIV infection and infectious diseases to co-chair the Panel. (nih.gov)
  • Participants 2185 sexually active female students, mean age 21 years (range 16-27), 38% from ethnic minorities, who took part in the POPI (prevention of pelvic infection) chlamydia screening trial in 2004-08 and who provided duplicate, self taken vaginal swabs and completed questionnaires at baseline. (bmj.com)
  • These results suggest that the increasing knowledge about the importance of HPV infection is probably leading to new prevention strategies for this disease. (springer.com)
  • Although there isn't yet any evidence to show whether HPV vaccination is effective at preventing oral HPV infections, results like these are vital to help inform prevention program in the future. (affleap.com)
  • This study explored the HR-HPV infection positivity in relation to sociodemographic, sexual behavior characteristics and knowledge about HPV and CC prevention among women who visited the Arkhangelsk clinical maternity hospital named after Samoylova, Russia. (bibsys.no)
  • Human papillomavirus infection and the multistage carcinogenesis of cervical cancer. (nih.gov)
  • Conclusion: Infections with multiple HPV types seem to act synergistically in cervical carcinogenesis. (aacrjournals.org)
  • HPV infection may play a role in colorectal carcinogenesis. (aacrjournals.org)
  • Detection of HPV DNA in colorectal cancer tissues by in situ hybridization ( 12 ) and PCR ( 13 - 17 ) has suggested that HPV infection might be associated with the carcinogenesis of colorectal cancer. (aacrjournals.org)
  • 1 However, cervical carcinogenesis is not facilitated by HPV infection alone, but it also associated with environmental factors, such as multiple sex partners and sexually transmitted diseases. (medsci.org)
  • Since the late 1990s, studies on the molecular basis of carcinogenesis have provided evidence strongly supporting the role of both HPV infection and smoking in the development of cervical cancer. (omicsonline.org)
  • Introduction Human papillomavirus (HPV) is considered necessary cause of invasive cervical cancer (ICC), but relations between different HPV types and other sexually transmitted infections in cervical carcinogenesis are unresolved. (bmj.com)
  • This trend, suggestive of a resurgence in cervical cancer, has also been observed in many European countries and could reflect increased cancer detection by the use of new diagnostic techniques, such as human papillomavirus (HPV) testing and cervicography, or it could be the result of a cohort effect. (cmaj.ca)
  • A cohort effect of the sexual revolution may be masking an increase in human papillomavirus detection at menopause in the United States. (springer.com)
  • The goal of this study was to estimate the prevalence and assess risk factors of oral HPV infection among young men participating in the HPV Infection and Transmission among Couples through Heterosexual Activity (HITCH) cohort study. (aacrjournals.org)
  • Given the contradictory nature of the literature regarding the role of human papillomaviruses and polyomaviruses in the pathogenesis of urothelial bladder cancer (UBC), we sought to investigate the frequency of their involvement in a large cohort of primary UBCs. (urotoday.com)
  • RESULTS: The prevalence of oral HR-HPV infection in this cohort was 2.2% (15/680) with 0.7% (5/680) positive for HPV16 or HPV18. (whiterose.ac.uk)
  • RESULTS: Human papillomavirus DNA was found in 61% of samples analyzed (185/301). (mendeley.com)
  • Human papillomavirus DNA was detected in 79.3% of specimens from women with definite cervical disease (627 of 791), in 23.7% of borderline atypia subjects (64 of 270), and in 6.4% of normal subjects (101 of 1566). (ovid.com)
  • Of 143 women with baseline carcinogenic HPV infection, 20 (14% (8.3% to 19.7%) had infection with the same carcinogenic HPV type(s) detected after 12-28 months. (bmj.com)
  • Human papillomavirus (HPV) vaccination rates are declined due to the COVID-19 pandemic, finds a new study. (medindia.net)
  • Risk of high-grade cervical intraepithelial neoplasia, a precancerous condition is low among women who had the human papillomavirus (HPV) vaccination, finds a new study. (medindia.net)
  • Vaccination of both genders can prevent HPV infections much more effectively than the vaccination of girls only, reveals a new study. (medindia.net)
  • Extending the U.S. human papillomavirus (HPV) vaccination schedule to involve women and men aged 45 would produce proportionately small health benefits compared with the current immunization program. (medindia.net)
  • Papillomaviruses-to vaccination and beyond. (springer.com)
  • Because vaccination is known to be mainly prophylactic (not therapeutic), it would have a benefit against new infections but not against latent infections. (aacrjournals.org)
  • The analyses provided here demonstrate that women who are infected with HPV-6, -11, -16, or -18 benefit from administration of the quadrivalent HPV (types 6, 11, 16, and 18) L1 VLP vaccine because they are protected from infections and disease caused by HPV types for which they are naive at the start of vaccination. (natap.org)
  • Cervical infection with HPV is common and occurs primarily through sexual transmission. (nih.gov)
  • After adjustment for the presence of HPV infection, the development of cervical intraepithelial neoplasia was also associated with younger age at first intercourse, the presence of serum antibodies to Chlamydia trachomatis, the presence of serum antibodies to cytomegalovirus, and cervical infection with Neisseria gonorrhoeae. (uni-bonn.de)
  • Cervical intraepithelial neoplasia is a common and apparently early manifestation of cervical infection by HPV, particularly types 16 and 18. (uni-bonn.de)
  • CONCLUSIONS: An elevated prevalence of HPV infection was detected in this population, which also has a high incidence of cervical cancer. (mendeley.com)
  • While HIV-positive men have a higher rate of HPV infection and abnormal cells in the anal canal, the incidence of invasive anal cancer in HIV-positive men who have sex with men (MSM) does not appear to be higher than the cancer risk of HIV-negative MSM. (thebody.com)
  • 65 HPV-associated OPC incidence is four- to five-fold higher in males than in females, 66 and two- to three-fold higher among individuals with HIV infection. (nih.gov)
  • The data concerning the incidence of oral HPV-infection in HIV-positive men, especially in the era of highly antiretroviral therapy, are conflicting. (clinicaltrials.gov)
  • In several studies, perianal HPV-infections have been detected in up to 90% of HIV-positive men and a high incidence of anal dysplasia has been reported in these patients. (clinicaltrials.gov)
  • Prevalence, incidence, and estimated life-time risk of cervical human papillomavirus infections in a nonselected Finnish female population. (springer.com)
  • Human papillomavirus and the rising oropharyngeal cancer incidence in the United States. (clevelandclinic.org)
  • Human papillomavirus (HPV) infection is the principal cause of a distinct form of oropharyngeal squamous cell carcinoma that is increasing in incidence among men in the United States. (cdc.gov)
  • Estimate the 6-month incidence of HPV infection in this study population. (knowcancer.com)
  • Although high incidence and prevalence are found in both females and males soon after the onset of sexual activity, the vast majority of genital HPV infections are asymptomatic and clear within 1 to 2 years ( 4 , 5 ). (aacrjournals.org)
  • This benefit is important because the incidence of new HPV infections among such subjects is higher than that among women who are naive for all 4 HPV vaccine types. (natap.org)
  • The incidence rate was 4.23% (3/71), which is equal to 4.23 new cases of HPV infection per 100 people, per year of follow-up. (ecancer.org)
  • To date, only a few studies have reported on the relationship between multiple HPV infections and cervical neoplasia, and their results are not consistent. (aacrjournals.org)
  • Chronic infection in the uterine cervix epithelium is commonly regarded as an essential element of cancer development in this area, together with additional factors (high parity, nicotinism, long-lasting hormonal contraception, co-infections with other pathogens, immunity deficits and other poorly specified co-factors) may initiate cervical intraepithelial neoplasia (CIN). (termedia.pl)
  • Human papillomavirus (HPV) is the main cause of cervical neoplasia. (uni-bonn.de)
  • During the years 1982-1989, 2627 women were recruited into eight studies analyzing the relationship between human papillomavirus (HPV) infection and cervical neoplasia. (ovid.com)
  • This strategy seems to allow an early identification of populations at different risk level for this neoplasia because the absence of infection makes the risk of cancer negligible. (springer.com)
  • Human papillomavirus (HPV) has been associated with cervical intraepithelial neoplasia, but the temporal relation between the infection and the neoplasia remains unclear, as does the relative importance of the specific type of HPV, other sexually transmitted diseases, and other risk factors. (uni-bonn.de)
  • This study emphasizes the need for an early detection of HPV infections among HIV+ MSM in order to establish its utility to prevent anal neoplasia and cancer. (biomedcentral.com)
  • But the vaccine needs to be given before a person becomes sexually active, since it has no therapeutic efficacy against existing HPV infections. (eurekalert.org)
  • U.S. women who received one dose of the HPV vaccine may have gained similar protection against vaccine-type infections compared with those who received additional doses, reports a new study. (medindia.net)
  • A quadrivalent (types 6, 11, 16, and 18) human papillomavirus (HPV) L1 virus-like-particle (VLP) vaccine has been shown to be 95%-100% effective in preventing cervical and genital disease related to HPV-6, -11, -16, and -18 in 16-26-year-old women naive for HPV vaccine types. (natap.org)
  • The design of the quadrivalent HPV vaccine studies stand in contrast with a recent trial of a bivalent HPV vaccine, in which HPV infection was a contraindication to enrollment [5]. (natap.org)
  • Furthermore, the potential for vaccine-related adverse experiences in women who had already mounted anti-HPV responses to natural infection has not yet been ruled out [12, 13]. (natap.org)
  • A landmark report on the effectiveness of the quadrivalent human papillomavirus vaccine (4vHP) in the U.S. is now a matter of medical record. (medworm.com)
  • Janssen Pharmaceuticals, Inc. (Janssen) announced today that the company has entered into a definitive collaboration and license agreement with Bavarian Nordic to leverage their MVA-BN(R) technology, jointly with Janssen's own AdVac(R) technology, in the development and commercialization of a heterologous prime-boost vaccine for the treatment of Human Papillomavirus (HPV) chronic infections which can lead to cancer. (perssupport.nl)
  • The goal is to develop a therapeutic vaccine which aims to intercept HPV infection-related disease, particularly in women and men who are diagnosed with HPV early, by enhancing the ability of the immune system to treat chronic infections and prevent progression to cancer. (perssupport.nl)
  • Human papillomavirus has been associated with head and neck squamous cell carcinoma. (scielo.br)
  • A letter to the editor is presented in response to an article on human papillomavirus infection as a risk factor for head and neck squamous-cell carcinoma. (ebscohost.com)
  • HPV is linked to the development of a type of cancer known as oral squamous cell carcinoma (OSCC), but little is known about how the infection is spread, or how common it is in the mouth. (affleap.com)
  • HIV-infected individuals should use latex condoms during every act of sexual intercourse to reduce the risk of exposure to sexually transmitted pathogens, including human papillomavirus (HPV) (AII) . (nih.gov)
  • Most people get a genital HPV infection through direct sexual contact, including vaginal, anal, and oral sex. (healthline.com)
  • There is a significantly higher risk of anal cancer in the "men who have sex with men" (MSM) population, especially in those with concurrent HIV infection. (uspharmacist.com)
  • In the present study we determined the prevalence and nature of HPV co-infections in the anal canal of 324 HIV+ MSM attending a high specialty medical center in Mexico City, DNA extraction and amplification with generic primers for HPV was performed, followed by detection of specific types and co-infections with INNO-Lipa, and identification of variants by amplification and sequencing of the E6 and LCR region of HPV 16. (biomedcentral.com)
  • 10+ parejas sexuales masculinas en la vida (TPa=3.06, IC95%:1.4-6.68) y 1+ parejas masculinas (sexo anal) recientes (TPa=2.28, IC95%:1.15-4.5). (scielosp.org)
  • Tasas de incidencia para infección anal: VPH alto-riesgo=7.8/1000 persona-meses (IC95%:6.0-10.1), VPH 16=1.8/1000 persona-meses (95%IC:1.1-2.9), tipos en vacuna tetravalente=3.4/1000 persona-meses y tipos en vacuna nonavalente=5.5/1000 persona-meses. (scielosp.org)
  • Men are more likely to have oral HPV infection than women. (medlineplus.gov)
  • Like with men, many women that get HPV don't have any symptoms and the infection goes away without causing any health problems. (healthline.com)
  • One study found that 75 percent of sexually active men and women under 50 have, or have had, an HPV infection, while 10,000 women annually develop cervical cancer, more than 90 percent of which is caused by HPV. (webwire.com)
  • The human papillomavirus (HPV) is a sexually transmitted infection common among men and women across all geographic and socioeconomic subgroups worldwide. (hindawi.com)
  • Some studies have shown a U-shaped curve with regards to HPV infection, meaning infection rates peak in women under the age of 30 and also in women aged 55-64 years [ 15 ]. (hindawi.com)
  • School-based human papillomavirus (HPV) immunization program reduced rates of cervical pre-cancer in British Columbia, Canada women dramatically, according to a new study. (medindia.net)
  • Human papillomavirus (HPV) infection is the major risk factor for development of cervical cancer, 1,2 the fourth most common cancer in women worldwide. (nih.gov)
  • 12-16 Penetrative sexual intercourse is not strictly necessary for HPV transmission, 17 but it is the primary risk factor for HPV infection, and HPV prevalence is low in young women who report only non-penetrative sexual contact. (nih.gov)
  • 17,18 The vast majority of cervical HPV infections resolve or become latent and undetectable, but in a subset of women, infection persists. (nih.gov)
  • 2 It is estimated that 50% of sexually active males will acquire a genital HPV infection in their lifetime, and the vast majority of women, at least 80%, will have acquired the infection by the age of 50 years. (uspharmacist.com)
  • HPV infection is most common in sexually active young women 25 years of age or younger but cervical cancer is common in older woman, suggesting infection at younger age and slow progression to cancer [ 10 ]. (intechopen.com)
  • The most significant predictor for adquiring HPV infection in men or women appears to be the life time number of sexual parteners [ 11 , 12 , 13 ]. (intechopen.com)
  • Association of Epstein Barr virus infection (EBV) with breast cancer in rural Indian women. (springer.com)
  • Postmenopausal women are still at risk of acquiring new HPV infections, as well as of having reactivation of latent ones. (springer.com)
  • Bruni L, Diaz M, Castellsagué X, Ferrer E, Bosch FX, de Sanjosé S. Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findings. (springer.com)
  • Brown DR, Weaver B. Human papillomavirus in older women: new infection or reactivation? (springer.com)
  • Behavioral/lifestyle and immunologic factors associated with HPV infection among women older than 45 years. (springer.com)
  • Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. (springer.com)
  • Cervical human papillomavirus screening among older women. (springer.com)
  • Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women. (springer.com)
  • It is estimated that HPV infections account for 70% of all cases of cervical cancer in women. (drpaul.com)
  • The investigators propose a longitudinal study of 500 women in order to determine rates and risk factors for HPV infections in 30-50 year old women. (knowcancer.com)
  • Bąk B, Sikorski M, Wrześniewska M. Health awareness among young women vaccinated against human papillomavirus infections. (termedia.pl)
  • Among women with normal cytology, HPV infections peaked first in women younger than 25 years, and they peaked again at age 55 years or older with predominantly non-cancer-associated types of HPV and uncharacterized HPV types. (uni-bonn.de)
  • The aim of this study was to evaluate the relationship between bacterial STI and HPV infection among asymptomatic sexually active women. (medsci.org)
  • The objective of this study was to determine whether cervico-vaginal HPV infection increases the risk of HIV acquisition in women independent of other common STIs. (rti.org)
  • Cervico-vaginal HPV infection was associated with an increased risk of HIV acquisition in women, and specific HPV types were implicated in this association. (rti.org)
  • However, given the high prevalence of HPV infection in women, further investigation of the role of HPV in HIV transmission is warranted. (rti.org)
  • There is also a paucity of data concerning the source of HPV infection in older women, e.g., those older than 40 years. (aacrjournals.org)
  • There are two competing hypotheses to explain the occurrence of presumably incident HPV infection in such women ( 6 - 8 ). (aacrjournals.org)
  • One of the justifications for vaccinating adult women, and especially older women, against HPV depends on understanding whether an infection represents a true new episode, or the re-activation of an earlier infection that has remained latent and undetected. (aacrjournals.org)
  • In an effort to inform the debate about the cause of reinfection and to stimulate further research, we analyzed the association between infection/reinfection (with the same or different types that women had been exposed to in the past) and new sexual partners at the time the infection episodes were detected. (aacrjournals.org)
  • More than 25% of the 16-26-year-old women enrolled in these trials had serological or polymerase chain reaction (PCR) evidence of previous or current infection with HPV-6, -11, -16, or -18. (natap.org)
  • On the basis of the presence of HPV DNA sequences women were separated into two groups: "infected" and "non infected" and a statistical analysis of the factors potentially associated with the infection group membership was carried out. (springer.com)
  • Among women age ≤ 30 years, 52% had HPV infection compared to 23% of those women who were older than 45 years (p = 0.006). (biomedcentral.com)
  • The prevalence ratio (PR) and 95% confidence interval (CI) was 2.26 (1.17, 4.34) for any HPV infection, 3.83 (1.23, 11.94) for Group 1 HPV (definite carcinogens), and 2.19 (0.99, 4.84) for Group 2a or 2b HPV (probable or possible carcinogens) types, among women aged 18-30 years, compared to women who were older than 45 years. (biomedcentral.com)
  • The prevalence of HPV infection was highest among younger women and decreased steadily with age among this population of urban Nigerian women. (biomedcentral.com)
  • Women's knowledge regarding the effects of cigarette smoking and human papillomavirus (HPV) infection on the development of cervical cancer as well as the appropriate preventive measures should play a significant part in health education of women. (omicsonline.org)
  • The aim of the study conducted in a sample of women from different socio-economic groups was to assess women's knowledge regarding the effects of cigarette smoking and HPV infection on the development of cervical cancer. (omicsonline.org)
  • Women having multiple sex partners are reportedly at an increased risk of HPV infection. (biomedcentral.com)
  • Awareness of cervical cancer and prevalence of human papillomavirus and other sexually transmitted infections among women in rural Nepal. (bibsys.no)
  • The aims of this thesis were to explore the knowledge of cervical cancer among Nepalese women, to investigate the feasibility and impact of community-based education on cervical cancer awareness, to determine the prevalence of human papillomavirus (HPV) infection and other selected sexually transmitted infections (STIs) and their risk factors among married women in rural Nepal. (bibsys.no)
  • A HR HPV infection was acquired by 12.8% of the women during follow-up. (arctichealth.org)
  • CONCLUSIONS: The prevalence of oral infection with HR-HPV in adult men and women in Sheffield in the North of England was low. (whiterose.ac.uk)
  • Effective prophylactic vaccines are available against human papillomavirus (HPV) types 6, 11, 16, and 18 which are licensed for routine use among young women. (biomedcentral.com)
  • HPV vaccines can prevent the most common types of infection. (wikipedia.org)
  • The findings don't change screening or vaccines at this point but could be important, for example, in understanding how to determine which HPV infections pose the greatest risk of producing cancer," Burk says. (eurekalert.org)
  • With the recent impetus to include HPV testing in cervical cancer screening programs and the prospect that efficacious HPV vaccines will become available in the near future, it becomes imperative to understand the role played by multiple HPV infections. (aacrjournals.org)
  • According to the new Pharmacor study titled 'Human Papillomavirus,' the most significant driver of the market will be the launch of prophylactic vaccines, the earliest of which are likely to be from Merck and GlaxoSmithKline/MedImmune. (infectioncontroltoday.com)
  • We expect the prophylactic vaccines to have a high level of safety and efficacy, and, given the level of physician awareness about the consequences of HPV infection, we expect these vaccines to benefit from high uptake and premium pricing,' said Aarti Raja, PhD, an analyst at Decision Resources. (infectioncontroltoday.com)
  • We estimated the prevalence of oral human papillomavirus (HPV) and assessed risk factors among young heterosexual men participating in the HPV Infection and Transmission among Couples through Heterosexual Activity (HITCH) study. (aacrjournals.org)
  • Polymerase chain reaction amplification and restriction enzyme typing as an accurate and simple way to detect and identify human papillomaviruses. (springer.com)
  • Mechanisms of human papillomavirus-induced oncogenesis. (springer.com)
  • Almost three decades later, in 2008, Professor Harald zur Hausen from Heidelberg (Germany) was awarded the Nobel Prize in Physiology or Medicine for describing the role of papillomavirus in oncogenesis . (omicsonline.org)
  • This article is about oral HPV infection. (medlineplus.gov)
  • Oral HPV infection shows no symptoms. (medlineplus.gov)
  • An oral HPV infection has no symptoms and cannot be detected by a test. (medlineplus.gov)
  • Risk factors for oral HPV infection include smoking and sexual behaviors as well as demographic characteristics ( 2-4 ). (aacrjournals.org)
  • Moreover, immunosuppressed individuals are at an increased risk of oral HPV infection ( 5 ). (aacrjournals.org)
  • Therefore, further studies are needed to clarify the natural history of oral HPV infection. (aacrjournals.org)
  • Prevalence of oral HPV infection in the United States, 2009-2010. (clevelandclinic.org)
  • Oral HPV infection in 324 children in the Finnish Family HPV Study during the first 6 years of life. (cdc.gov)
  • Their findings indicate that sexual activity is the most common source of oral HPV infection. (affleap.com)
  • Human papillomavirus (HPV) is a major risk factor for several types of cancer including oropharyngeal cancer. (aacrjournals.org)
  • Sex workers are at increased risk for sexually transmitted infections (STI), human papillomavirus (HPV) and hence cervical cancer. (bmj.com)
  • Nevertheless, it has been established that human papillomavirus (HPV) infection is the most important, but not the exclusive, risk factor to cervical cancer. (scielo.br)
  • However, little is known about these co-factors in relation to the risk of HPV infection (Cuschieri et al. (scielo.br)
  • Associations between oral cancer and risk factors usually associated with HPV infection, such as oral sex and number of lifetime sexual partners, were examined by logistic regression and were not associated with oral cancer. (archives-ouvertes.fr)
  • Sexually transmitted infections (STIs) such as herpes simplex virus (HSV)-2 are associated with an increased risk of HIV infection. (rti.org)
  • Oral human papillomavirus HPV infection increases cancer risk by around 50 percent, according to the research team from Ohio State University Comprehensive Cancer Center. (affleap.com)
  • However, the prevalence and risk factors of HPV infection in female sex workers (FSWs) vary considerably across racial/ethnic, socioeconomic, and geographic groups. (biomedcentral.com)
  • This study aimed to determine the prevalence and risk factors of HPV infection in FSWs in Northeast China. (biomedcentral.com)
  • Age of first sexual intercourse and post-menopause are two independent risk factors for HPV infection in this special group of population. (biomedcentral.com)
  • Intensified and coordinated efforts from government, public health sector, communities and families are needed to reduce the risk of HPV infection in this specific group of population. (biomedcentral.com)
  • Being married to a husband with at least one previous marriage was found to be a risk factor for both infections. (bibsys.no)
  • Secondary outcome measures included associations between risk factors, folate status and infection. (whiterose.ac.uk)
  • P2-164 Human papillomavirus, other sexually transmitted infections and risk of cervical cancer. (bmj.com)
  • Infection with some types of HPV is the greatest risk factor for cervical cancer, followed by smoking. (wikipedia.org)
  • HIV infection is also a risk factor. (wikipedia.org)
  • HPV is highly communicable and is transmitted by sexual contact during both acute and latent infection. (uspharmacist.com)
  • infections appearing later in life would mostly represent the reactivation of such latent infections acquired many years earlier. (aacrjournals.org)
  • We hypothesized that a latent infection that became detectable later in life is unlikely to be associated with new sexual partners, whereas new infections (with new types as well as for the same types a woman had before) would represent exposure to new sexual partners. (aacrjournals.org)
  • The human papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide [ 1 , 2 ]. (hindawi.com)
  • One of the viruses contributing to the statistics of cancerous diseases is human papillomavirus (HPV). (hindawi.com)
  • The chances of host sexual behavior manipulation in case of sexually transmitted infections caused by viruses are very high due to the intense selection pressure present in certain specific ecological niches. (omicsonline.org)
  • HPV is the most common sexually transmitted infection globally. (wikipedia.org)
  • Human papillomavirus infection is the most common sexually transmitted infection. (medlineplus.gov)
  • Human papillomavirus (HPV)-a small, double-stranded DNA virus-is the most common sexually transmitted infection in the United States. (uspharmacist.com)
  • Human papillomavirus (HPV)-infection belong to the most common sexually transmitted diseases worldwide. (clinicaltrials.gov)
  • HPV is the most common sexually transmitted infection (STI), globally. (wikipedia.org)
  • Human papillomavirus (HPV) infections are among the most common sexually transmitted infections ( 1 , 2 ). (aacrjournals.org)
  • Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the U.S., with nearly 80 million people infected with some type of HPV at some point in their lives [1]. (medworm.com)
  • Genital human papilloma virus (HPV) infection is the most common sexually transmitted infection. (medworm.com)
  • Human papillomavirus (HPV) is thought to be the most common sexually transmitted infection in the world [ 1 ]. (biomedcentral.com)
  • Infections with HPV represent the most common sexually transmitted disease worldwide. (biomedcentral.com)
  • How is oropharyngeal human papilloma virus (HPV) infection found? (clevelandclinic.org)
  • A wide search strategy was employed in order to avoid publication biases and to assess studies dealing only with oral and/or oropharyngeal human papillomavirus infections in the Brazilian population. (scielo.br)
  • Some HPV types, such as HPV-5, may establish infections that persist for the lifetime of the individual without ever manifesting any clinical symptoms. (wikipedia.org)
  • Certain types of HPV can cause an infection in the mouth and throat. (medlineplus.gov)
  • The microbial composition and its association with HPV infection, including 27 HPV types, were analyzed. (nature.com)
  • 2 More than 170 types of HPV have been identified and are classified as cutaneous or mucosal subtypes on the basis of their preferred site of infection. (scielo.org.za)
  • Such reactivations could result from one or more non-mutually exclusive reasons, such as hormonal changes during perimenopause or waning of cellular and humoral immunity against the HPV types that caused the original infections. (aacrjournals.org)
  • HPV infection is generally transmitted by skin-to-skin contact and infects the epithelial cells in genital mucosa, oral mucosa, or skin [ 12 , 13 ]. (hindawi.com)
  • Human papillomavirus (HPV) infection of epidermal or mucosal epithelial cells causes benign and sometimes malignant neoplasms. (aacrjournals.org)
  • Previous sexually transmitted infections were also investigated by serology. (nih.gov)
  • Sexual intimacy, which includes kissing, is a major mode of transmission in case of HPV whereas in the case of other sexually transmitted infections like HIV and HBV non-sexual factors like contaminated blood transfusions contribute significantly in the spread of the virus to the other host. (omicsonline.org)
  • The exploration of infectious diseases with such perspective can offer great insights for the better understanding of the sexually transmitted infections. (omicsonline.org)
  • For Group II, the Pap test was also the most relevant variable that was analysed, but the history of other sexually transmitted diseases and the use of alcohol were additional factors that were implicated in infection. (scielo.br)
  • This study aimed to determine the role of asymptomatic bacterial sexually transmitted infections (STIs), such as Chlamydia trachomatis ( Ct ), Mycoplasma genitalium ( Mg ), Mycoplasma hominis (Mh) , and Ureaplasma urealyticum ( Uu ) in human papillomavirus (HPV) infection. (medsci.org)
  • The study findings are crucial to understand Nepal's cervical cancer burden and to make preventive strategies to reduce cervical cancer burden and sexually transmitted infections in Nepal. (bibsys.no)
  • We confirmed the sexually transmitted nature of the infection. (arctichealth.org)
  • The disparity in results may originate from the fact that many studies have relied on cross-sectional detection of type-specific HPV infections and thereby may have underestimated the cumulative lifetime diversity of exposure to HPV. (aacrjournals.org)
  • 3 Therefore, detection of Mycoplasma or Chlamydia infection may play a role in decreasing the prevalence of cervical cancer. (medsci.org)