Common Bile Duct: The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.Common Bile Duct Neoplasms: Tumor or cancer of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Common Bile Duct Diseases: Diseases of the COMMON BILE DUCT including the AMPULLA OF VATER and the SPHINCTER OF ODDI.Bile Ducts: The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.Bile Duct Neoplasms: Tumors or cancer of the BILE DUCTS.Gallstones: Solid crystalline precipitates in the BILIARY TRACT, usually formed in the GALLBLADDER, resulting in the condition of CHOLELITHIASIS. Gallstones, derived from the BILE, consist mainly of calcium, cholesterol, or bilirubin.Cholangiopancreatography, Endoscopic Retrograde: Fiberoptic endoscopy designed for duodenal observation and cannulation of VATER'S AMPULLA, in order to visualize the pancreatic and biliary duct system by retrograde injection of contrast media. Endoscopic (Vater) papillotomy (SPHINCTEROTOMY, ENDOSCOPIC) may be performed during this procedure.Cholangiography: An imaging test of the BILIARY TRACT in which a contrast dye (RADIOPAQUE MEDIA) is injected into the BILE DUCT and x-ray pictures are taken.Bile: An emulsifying agent produced in the LIVER and secreted into the DUODENUM. Its composition includes BILE ACIDS AND SALTS; CHOLESTEROL; and ELECTROLYTES. It aids DIGESTION of fats in the duodenum.Bile Duct Diseases: Diseases in any part of the ductal system of the BILIARY TRACT from the smallest BILE CANALICULI to the largest COMMON BILE DUCT.Choledocholithiasis: Presence or formation of GALLSTONES in the COMMON BILE DUCT.Bile Ducts, Extrahepatic: Passages external to the liver for the conveyance of bile. These include the COMMON BILE DUCT and the common hepatic duct (HEPATIC DUCT, COMMON).Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).Cholestasis, Extrahepatic: Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.Cholecystectomy, Laparoscopic: Excision of the gallbladder through an abdominal incision using a laparoscope.Cholecystectomy: Surgical removal of the GALLBLADDER.Sphincterotomy, Endoscopic: Incision of Oddi's sphincter or Vater's ampulla performed by inserting a sphincterotome through an endoscope (DUODENOSCOPE) often following retrograde cholangiography (CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE). Endoscopic treatment by sphincterotomy is the preferred method of treatment for patients with retained or recurrent bile duct stones post-cholecystectomy, and for poor-surgical-risk patients that have the gallbladder still present.Bile Acids and Salts: Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.Bile Ducts, Intrahepatic: Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct.Jaundice, Obstructive: Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.Cholangiopancreatography, Magnetic Resonance: Non-invasive diagnostic technique for visualizing the PANCREATIC DUCTS and BILE DUCTS without the use of injected CONTRAST MEDIA or x-ray. MRI scans provide excellent sensitivity for duct dilatation, biliary stricture, and intraductal abnormalities.Sphincter of Oddi: The sphincter of the hepatopancreatic ampulla within the duodenal papilla. The COMMON BILE DUCT and main pancreatic duct pass through this sphincter.Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.Cystic Duct: The duct that is connected to the GALLBLADDER and allows the emptying of bile into the COMMON BILE DUCT.Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).Ampulla of Vater: A dilation of the duodenal papilla that is the opening of the juncture of the COMMON BILE DUCT and the MAIN PANCREATIC DUCT, also known as the hepatopancreatic ampulla.Pancreatic Ducts: Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM.Biliary Tract Diseases: Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.Hepatic Duct, Common: Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct.Biliary Tract: The BILE DUCTS and the GALLBLADDER.Ligation: Application of a ligature to tie a vessel or strangulate a part.Gallbladder: A storage reservoir for BILE secretion. Gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the CYSTIC DUCT to the DUODENUM, for degradation of dietary lipid.Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.Sphincterotomy, Transhepatic: Surgery of the smooth muscle sphincter of the hepatopancreatic ampulla to relieve blocked biliary or pancreatic ducts.Choledochal Cyst: A congenital anatomic malformation of a bile duct, including cystic dilatation of the extrahepatic bile duct or the large intrahepatic bile duct. Classification is based on the site and type of dilatation. Type I is most common.Biliary Tract Surgical Procedures: Any surgical procedure performed on the biliary tract.Biliary Fistula: Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.Choledochostomy: Surgical formation of an opening (stoma) into the COMMON BILE DUCT for drainage or for direct communication with a site in the small intestine, primarily the DUODENUM or JEJUNUM.Adenoma, Bile Duct: A benign tumor of the intrahepatic bile ducts.Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Endoscopes: Instruments for the visual examination of interior structures of the body. There are rigid endoscopes and flexible fiberoptic endoscopes for various types of viewing in ENDOSCOPY.Duodenoscopy: Endoscopic examination, therapy or surgery of the luminal surface of the duodenum.Cholecystitis: Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.Imino AcidsGallbladder Diseases: Diseases of the GALLBLADDER. They generally involve the impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, neoplasms, or other diseases.Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.Lithotripsy: The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.Adenomyoma: A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)Gallbladder Neoplasms: Tumors or cancer of the gallbladder.Technetium Tc 99m Disofenin: A radiopharmaceutical used extensively in cholescintigraphy for the evaluation of hepatobiliary diseases. (From Int Jrnl Rad Appl Inst 1992;43(9):1061-4)Endoscopy, Digestive System: Endoscopic examination, therapy or surgery of the digestive tract.Endoscopy: Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.Dilatation, Pathologic: The condition of an anatomical structure's being dilated beyond normal dimensions.Pancreaticoduodenectomy: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).Cholecystitis, Acute: Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.Sphincter of Oddi Dysfunction: Organic or functional motility disorder involving the SPHINCTER OF ODDI and associated with biliary COLIC. Pathological changes are most often seen in the COMMON BILE DUCT sphincter, and less commonly the PANCREATIC DUCT sphincter.Jejunostomy: Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.Cholecystolithiasis: Presence or formation of GALLSTONES in the GALLBLADDER.Duodenum: The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.Bilirubin: A bile pigment that is a degradation product of HEME.Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).Pancreatic Diseases: Pathological processes of the PANCREAS.Intraoperative Period: The period during a surgical operation.Endosonography: Ultrasonography of internal organs using an ultrasound transducer sometimes mounted on a fiberoptic endoscope. In endosonography the transducer converts electronic signals into acoustic pulses or continuous waves and acts also as a receiver to detect reflected pulses from within the organ. An audiovisual-electronic interface converts the detected or processed echo signals, which pass through the electronics of the instrument, into a form that the technologist can evaluate. The procedure should not be confused with ENDOSCOPY which employs a special instrument called an endoscope. The "endo-" of endosonography refers to the examination of tissue within hollow organs, with reference to the usual ultrasonography procedure which is performed externally or transcutaneously.Liver: A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.Duodenal Neoplasms: Tumors or cancer of the DUODENUM.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Cholecystostomy: Establishment of an opening into the gallbladder either for drainage or surgical communication with another part of the digestive tract, usually the duodenum or jejunum.Bile Reflux: Retrograde bile flow. Reflux of bile can be from the duodenum to the stomach (DUODENOGASTRIC REFLUX); to the esophagus (GASTROESOPHAGEAL REFLUX); or to the PANCREAS.Liver Cirrhosis, Experimental: Experimentally induced chronic injuries to the parenchymal cells in the liver to achieve a model for LIVER CIRRHOSIS.Lithotripsy, Laser: Fragmentation of CALCULI, notably urinary or biliary, by LASER.Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.Intraoperative Care: Patient care procedures performed during the operation that are ancillary to the actual surgery. It includes monitoring, fluid therapy, medication, transfusion, anesthesia, radiography, and laboratory tests.Cholangiocarcinoma: A malignant tumor arising from the epithelium of the BILE DUCTS.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Liver Function Tests: Blood tests that are used to evaluate how well a patient's liver is working and also to help diagnose liver conditions.Duodenal Diseases: Pathological conditions in the DUODENUM region of the small intestine (INTESTINE, SMALL).Thoracic Duct: The largest lymphatic vessel that passes through the chest and drains into the SUBCLAVIAN VEIN.Calculi: An abnormal concretion occurring mostly in the urinary and biliary tracts, usually composed of mineral salts. Also called stones.Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cirrhosis involves the destruction of small intra-hepatic bile ducts and bile secretion. Secondary biliary cirrhosis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Ascaridida: An order of nematodes of the subclass SECERNENTEA. Its organisms possess two or three pairs of dorsolateral caudal papillae.Adenocarcinoma, Papillary: An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Lithiasis: A condition characterized by the formation of CALCULI and concretions in the hollow organs or ducts of the body. They occur most often in the gallbladder, kidney, and lower urinary tract.Tomography, X-Ray Computed: Tomography using x-ray transmission and a computer algorithm to reconstruct the image.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Hepatopulmonary Syndrome: A syndrome characterized by the clinical triad of advanced chronic liver disease, pulmonary vascular dilatations, and reduced arterial oxygenation (HYPOXEMIA) in the absence of intrinsic cardiopulmonary disease. This syndrome is common in the patients with LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL).Pancreas: A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.Colic: A clinical syndrome with intermittent abdominal pain characterized by sudden onset and cessation that is commonly seen in infants. It is usually associated with obstruction of the INTESTINES; of the CYSTIC DUCT; or of the URINARY TRACT.Intraoperative Complications: Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.Laparoscopy: A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.Neoplasms, Multiple Primary: Two or more abnormal growths of tissue occurring simultaneously and presumed to be of separate origin. The neoplasms may be histologically the same or different, and may be found in the same or different sites.Pancreatitis, Chronic: INFLAMMATION of the PANCREAS that is characterized by recurring or persistent ABDOMINAL PAIN with or without STEATORRHEA or DIABETES MELLITUS. It is characterized by the irregular destruction of the pancreatic parenchyma which may be focal, segmental, or diffuse.Ursodeoxycholic Acid: An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.Diverticulum: A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.Anastomosis, Roux-en-Y: A Y-shaped surgical anastomosis of any part of the digestive system which includes the small intestine as the eventual drainage site.Adenoma, Villous: An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)Cholecystography: Radiography of the gallbladder after ingestion of a contrast medium.Bile Canaliculi: Minute intercellular channels that occur between liver cells and carry bile towards interlobar bile ducts. Also called bile capillaries.Liver Diseases: Pathological processes of the LIVER.Anastomosis, Surgical: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.Cholagogues and Choleretics: Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic).Postcholecystectomy Syndrome: Abdominal symptoms after removal of the GALLBLADDER. The common postoperative symptoms are often the same as those present before the operation, such as COLIC, bloating, NAUSEA, and VOMITING. There is pain on palpation of the right upper quadrant and sometimes JAUNDICE. The term is often used, inaccurately, to describe such postoperative symptoms not due to gallbladder removal.Fascioliasis: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.Preoperative Care: Care given during the period prior to undergoing surgery when psychological and physical preparations are made according to the special needs of the individual patient. This period spans the time between admission to the hospital to the time the surgery begins. (From Dictionary of Health Services Management, 2d ed)Salivary Ducts: Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.Portal Vein: A short thick vein formed by union of the superior mesenteric vein and the splenic vein.Technetium Tc 99m Lidofenin: A nontoxic radiopharmaceutical that is used in RADIONUCLIDE IMAGING for the clinical evaluation of hepatobiliary disorders in humans.Iatrogenic Disease: Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.Bile Pigments: Linear TETRAPYRROLES that give a characteristic color to BILE including: BILIRUBIN; BILIVERDIN; and bilicyanin.Stents: Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Cysts: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Ultrasonography: The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz.Dilatation: The act of dilating.Video-Assisted Surgery: Endoscopic surgical procedures performed with visualization via video transmission. When real-time video is combined interactively with prior CT scans or MRI images, this is called image-guided surgery (see SURGERY, COMPUTER-ASSISTED).Duodenal Obstruction: Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.Incidental Findings: Unanticipated information discovered in the course of testing or medical care. Used in discussions of information that may have social or psychological consequences, such as when it is learned that a child's biological father is someone other than the putative father, or that a person tested for one disease or disorder has, or is at risk for, something else.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Hemobilia: Hemorrhage in or through the BILIARY TRACT due to trauma, inflammation, CHOLELITHIASIS, vascular disease, or neoplasms.Mixed Tumor, Malignant: A malignant tumor composed of more than one type of neoplastic tissue. (Dorland, 27th ed)Digestive System Neoplasms: Tumors or cancer of the DIGESTIVE SYSTEM.Wolffian Ducts: A pair of excretory ducts of the middle kidneys (MESONEPHROI) of an embryo, also called mesonephric ducts. In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female.Liver Neoplasms: Tumors or cancer of the LIVER.Taurocholic Acid: The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.Pancreatic Pseudocyst: Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.Amylases: A group of amylolytic enzymes that cleave starch, glycogen, and related alpha-1,4-glucans. (Stedman, 25th ed) EC 3.2.1.-.Adenocarcinoma: A malignant epithelial tumor with a glandular organization.Foreign-Body Migration: Migration of a foreign body from its original location to some other location in the body.Hepatic Artery: A branch of the celiac artery that distributes to the stomach, pancreas, duodenum, liver, gallbladder, and greater omentum.Manometry: Measurement of the pressure or tension of liquids or gases with a manometer.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Acute Disease: Disease having a short and relatively severe course.Digestive System Fistula: An abnormal passage communicating between any components of the digestive system, or between any part of the digestive system and surrounding organ(s).Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Mullerian Ducts: A pair of ducts near the WOLFFIAN DUCTS in a developing embryo. In the male embryo, they degenerate with the appearance of testicular ANTI-MULLERIAN HORMONE. In the absence of anti-mullerian hormone, mullerian ducts give rise to the female reproductive tract, including the OVIDUCTS; UTERUS; CERVIX; and VAGINA.Pancreatic Fistula: Abnormal passage communicating with the PANCREAS.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Bacterial Translocation: The passage of viable bacteria from the GASTROINTESTINAL TRACT to extra-intestinal sites, such as the mesenteric lymph node complex, liver, spleen, kidney, and blood. Factors that promote bacterial translocation include overgrowth with gram-negative enteric bacilli, impaired host immune defenses, and injury to the INTESTINAL MUCOSA resulting in increased intestinal permeability. Bacterial translocation from the lung to the circulation is also possible and sometimes accompanies MECHANICAL VENTILATION.Pancreatectomy: Surgical removal of the pancreas. (Dorland, 28th ed)Biliary Atresia: Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.Methods: A series of steps taken in order to conduct research.Hypertension, Portal: Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
... biliary tract neoplasms MeSH C04.588.274.120.250 --- bile duct neoplasms MeSH C04.588.2220.127.116.11 --- common bile duct ... pancreatic ductal MeSH C04.588.274.780 --- peritoneal neoplasms MeSH C04.588.322.078 --- adrenal gland neoplasms MeSH C04.588. ... liver neoplasms, experimental MeSH C04.588.274.761 --- pancreatic neoplasms MeSH C04.588.274.761.249 --- adenoma, islet cell ... nose neoplasms MeSH C04.588.149.721.656 --- orbital neoplasms MeSH C04.588.149.721.828 --- skull base neoplasms MeSH C04.588. ...
... common bile duct neoplasms MeSH C06.130.320.120 --- bile duct neoplasms MeSH C06.130.320.120.280 --- common bile duct neoplasms ... pancreatic pseudocyst MeSH C06.689.667.249 --- adenoma, islet cell MeSH C06.689.667.249.500 --- insulinoma MeSH C06.689.667.500 ... bile duct neoplasms MeSH C06.301.120.250.250 --- common bile duct neoplasms MeSH C06.301.120.401 --- gallbladder neoplasms MeSH ... File "2006 MeSH Trees".) MeSH C06.130.120.120 --- bile duct neoplasms MeSH C06.130.120.120.280 --- common bile duct neoplasms ...
Serous cystic neoplasms can come to clinical attention in a variety of ways. The most common symptoms are very non-specific and ... a yellowing of the skin and eyes caused by obstruction of the bile duct), or weight loss. These signs and symptoms are not ... such as the intraductal papillary mucinous neoplasm and the mucinous cystic neoplasm), serous cystic neoplasms are almost ... The cysts do not communicate with the larger pancreatic ducts. In some cases a fine needle aspiration (FNA) biopsy can be ...
These tests will reveal dilatation of the pancreatic duct or one of the branches of the pancreatic duct. In some cases a fine ... The most common symptoms include abdominal pain, nausea and vomiting. The most common signs patients have when they come to ... a yellowing of the skin and eyes caused by obstruction of the bile duct), weight loss, and acute pancreatitis. These signs and ... Pancreatic mucinous cystic neoplasm Pancreatic serous cystadenoma Solid pseudopapillary neoplasm "Intraductal Papillary ...
Dixon, J. A.; Morgan, K. A.; Adams, D. B. (2009). "Management of common bile duct injury during partial gastrectomy". The ... Ellis, C. T.; Barbour, J. R.; Shary, T. M.; Adams, D. B. (2010). "Pancreatic cyst: Pseudocyst or neoplasm? Pitfalls in ... Morgan, K. A.; Fontenot, B. B.; Harvey, N. R.; Adams, D. B. (2010). "Revision of anastomotic stenosis after pancreatic head ... Theruvath, T. P.; Morgan, K. A.; Adams, D. B. (2010). "Mucinous cystic neoplasms of the pancreas: How much preoperative ...
Most gastrinomas are found in the gastrinoma triangle; this is bound by the junction of cystic and common bile ducts, junction ... USC Emedicine The Johns Hopkins University Pancreatic Islet Cell Tumor / Pancreatic Endocrine Neoplasms webpage Surgery ...
Less common types include mucinous cystic neoplasm and intraductal papillary biliary neoplasm. The diagnosis may be supported ... Liver cancer can also form from other structures within the liver such as the bile duct, blood vessels and immune cells. Cancer ... such as pancreatic cancer, stomach cancer, colon cancer and carcinoid tumors mainly of the appendix), but also from breast ... The majority of cholangiocarcimas occur in the hilar region of the liver, and often present as bile duct obstruction. If the ...
... gastrointestinal Colon cancer Extrahepatic bile duct cancer Gallbladder cancer Gastric (stomach) cancer Gastrointestinal ... For some common cancers, the English organ name is used. For example, the most common type of breast cancer is called ductal ... Marginal zone B-cell lymphoma Mast cell leukemia Mediastinal large B cell lymphoma Multiple myeloma/plasma cell neoplasm ... carcinoid tumor Gastrointestinal stromal tumor (GIST) Hepatocellular cancer Pancreatic cancer, islet cell Rectal cancer Bladder ...
... an abnormal yellowing of the skin and eyes often caused by blockage of the bile ducts) are more likely to have a pancreatic ... ". "Pancreatic Cancer FAQs". "Intraductal Papillary Mucinous Neoplasms of the Pancreas". Birkmeyer JD, Stukel TA, Siewers AE, ... The most common include CT scan (computerized axial tomography), magnetic resonance imaging (MRI), positron emission tomography ... MRI is a great method to visualize the pancreatic ducts, PET scanning can reveal the metabolic activity of a tumor, EUS ...
This results when a cancer in the head of the pancreas obstructs the common bile duct as it runs through the pancreas. ... The third type, pancreatic mucinous cystic neoplasms (MCNs) mainly occur in women, and may remain benign or progress to cancer ... Stage T1 pancreatic cancer Stage T2 pancreatic cancer Stage T3 pancreatic cancer Stage T4 pancreatic cancer Pancreatic cancer ... Pancreatic cancer is the fifth most common cause of death from cancer in the United Kingdom, and the fourth most common in the ...
... bile duct cancer, pancreatic cancer, small intestine cancer and colon cancer. In the colon, a field defect probably arises by ... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... One common feature of neoplastic progression is the expansion of a clone with a genetic or epigenetic alteration. This may be a ... A common cytotoxic chemotherapy used in a variety of cancers, 5-fluorouracil (5-FU), targets the TYMS pathway and resistance ...
Distal cholangiocarcinomas (those arising from the common bile duct) are generally treated surgically with a Whipple procedure ... Cholangiocarcinoma is a relatively rare neoplasm that is classified as an adenocarcinoma (a cancer that forms glands or ... biliary and pancreatic tumours". J Hepatol. 37 (6): 806-13. doi:10.1016/S0168-8278(02)00297-0. PMID 12445422. Welzel T, McGlynn ... Patient information on extrahepatic bile duct tumors, from the National Cancer Institute. Cancer.Net: Bile Duct Cancer The ...
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ...
... common bile duct - comorbidity - compassionate use trial - complementary and alternative medicine - complete blood count (CBC ... pancreatic cancer - pancreatic duct - pancreatic enzyme - pancreatic juice - pancreatitis - PAP, same as Pap smear - Pap smear ... neoplasm - nephrotomogram - nephrotoxic - nephroureterectomy - nerve block - nerve grafting - nerve-sparing radical ... bile duct - biliary - bilirubin - binding agent - bioavailable - biochanin A - biochemical reactions - biological response ...
It also receives bile and pancreatic juice through the pancreatic duct, controlled by the sphincter of Oddi. The primary ... A few of them are listed below, some of which are common, with up to 10% of people being affected at some time in their lives, ... Neoplasms (cancers) Adenocarcinoma Carcinoid Gastrointestinal stromal tumor (GIST) Lymphoma Sarcoma Leiomyoma Metastatic tumors ... Pancreatic lipase works with the help of the salts from the bile secreted by the liver and stored in the gall bladder. Bile ...
bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... This article about a neoplasm is a stub. You can help Wikipedia by expanding it.. *v ...
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Prognosis and treatment is the same as for the most common type of ovarian cancer, which is epithelial ovarian cancer. ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ...
Bile ducts: 2. Intrahepatic bile ducts, 3. Left and right hepatic ducts, 4. Common hepatic duct, 5. Cystic duct, 6. Common bile ... Two ducts, the main pancreatic duct and a smaller accessory pancreatic duct, run through the body of the pancreas, joining with ... "Solid pseudopapillary neoplasm of the pancreas: a single institution experience of 14 cases". HPB. 8 (2): 148-50. doi:10.1080/ ... forming the main pancreatic duct. The duct of the dorsal bud regresses, leaving the main pancreatic duct. ...
... it carries with it the ventral pancreatic bud and common bile duct. Upon reaching its final destination, the ventral pancreatic ... Patil TB, Shrikhande SV, Kanhere HA, Saoji RR, Ramadwar MR, Shukla PJ (2006). "Solid pseudopapillary neoplasm of the pancreas: ... The exocrine part has two main ducts, the main pancreatic duct and the accessory pancreatic duct. These drain enzymes through ... forming the main pancreatic duct. The duct of the dorsal bud regresses, leaving the main pancreatic duct. Differentiation of ...
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... AMHR2 (Persistent Müllerian duct syndrome II). *TGF beta receptors: Endoglin/Alk-1/SMAD4 (Hereditary hemorrhagic telangiectasia ...
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... The most common originating sites of carcinoid is the small bowel, particularly the ileum; carcinoid tumors are the most common ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... The next most common affected area is the respiratory tract, with 28% of all cases - per PAN-SEER data (1973 - 1999). The ...
Common bile duct *Choledocholithiasis. *Biliary dyskinesia. *Sphincter of Oddi dysfunction. Pancreatic. *Pancreatitis *Acute ... ಪಠ್ಯವು Creative Commons Attribution-ShareAlike License ನಡಿ ಲಭ್ಯವಿದೆ; ಮತ್ತಷ್ಟು ಷರತ್ತುಗಳು ಅನ್ವಯಿಸಬಹುದು. ಹೆಚ್ಚಿನ ವಿವರಗಳಿಗೆ ಬಳಕೆಯ ... Neoplasms and cancer. *Inflammatory bowel disease. *Gluten sensitivity. *Other. *Symptoms and signs *eponymous ...
Common bile duct *Choledocholithiasis. *Biliary dyskinesia. *Sphincter of Oddi dysfunction. Pancreatic. *Pancreatitis *Acute ... ಪಠ್ಯವು Creative Commons Attribution-ShareAlike License ನಡಿ ಲಭ್ಯವಿದೆ; ಮತ್ತಷ್ಟು ಷರತ್ತುಗಳು ಅನ್ವಯಿಸಬಹುದು. ಹೆಚ್ಚಿನ ವಿವರಗಳಿಗೆ ಬಳಕೆಯ ... Neoplasms and cancer. *Inflammatory bowel disease. *Gluten sensitivity. *Other. *Symptoms and signs *eponymous ...
Common bile duct *Choledocholithiasis. *Biliary dyskinesia. *Sphincter of Oddi dysfunction. Pancreatic. *Pancreatitis *Acute ... Neoplasms, benign or malignant. *Intussusception. *Volvulus. *Superior mesenteric artery syndrome, a compression of the ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ... Common consequences of these adhesions include small-bowel obstruction, chronic abdominal pain, pelvic pain, and infertility.[ ...
疼痛或無痛性的黃疸（皮膚或眼白變黃）：當腫瘤位於胰臟的頭部而造成總膽管（英語：common bile duct）阻塞時便會發生，有時也可能伴隨黑尿。 ... 最後一種則是主要發生在女性的胰黏液性囊狀腫瘤（英語：pancreatic mucinous cystic neoplasm）（MCNs），它可能維持良性或發展為惡性。如果腫瘤變大、造成
Pancreatic ductal carcinoma. *cystic neoplasms: Serous microcystic adenoma. *Intraductal papillary mucinous neoplasm ... bile duct: Cholangiocarcinoma. *Klatskin tumor. *gallbladder: Gallbladder cancer. Pancreas. *exocrine pancreas: Adenocarcinoma ... Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, ...
Common Bile Duct Neoplasms. James Farrell, MBChB Professor of Medicine. Director, Yale Center for Pancreatic Diseases ... Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Common Bile Duct Diseases; Common Bile Duct Neoplasms; ... Ileal Neoplasms; Intestinal Neoplasms; Pancreatic Cyst; Pancreatic Diseases; Pancreatic Fistula; Pancreatic Neoplasms; ... Barrett Esophagus; Bile Duct Neoplasms; Biliary Tract Diseases; Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; ...
... but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if ... 986 the waterjet necrosectomy device (wand): a novel instrument for management of pancreatic necrosis ... but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if ... More News: Bile , Computers , CT Scan , ERCP , Gastrectomy , Gastroenterology , Jaundice , Pancreas , Pathology , PET Scan , ...
... is a common option. Thus diabetes mellitus and hepatitis, for example, might belong more appropriately elsewhere, though not if ... the paper should concern pancreatic transplantation or virally-induced hepatoma. ... distal common bile duct cancers, duodenal cancers, intraductal papillary mucinous neoplasm, and neuroendocrine tumours [20-23]. ... The major indication for pancreatic resection is pancreatic cancer, the seventh most common cause of cancer-related mortality ...
... common bile duct stones, and pancreatic diseases (pancreatic neoplasms and chronic pancreatitis)12 and would be useful to ... There was no elevation of hepatic enzymes or bile duct dilation suggestive of microlithiasis. Abdominal ultrasound and CT scan ... 3 Bleeding may occur into the gastrointestinal tract and present as melena or hematochezia through the main pancreatic duct ( ... Hemodynamic instability occurred due to abdominal hemorrhage from two pseudoaneurysms inside an acute peri-pancreatic ...
... distal common bile duct, periampullary region and duodenum, and is... ... represents the standard surgical treatment for resectable malignancies of the pancreatic head, ... neuroendocrine and malignant intraductal papillary-mucinous neoplasms, cancers of the distal common bile duct (CBD), Vaterian ... and pancreatic duct [pancreatico-jejunostomy (PJS)]; (2) an end-to-side anastomosis between common hepatic duct and MJL [ ...
Choledochal cysts are congenital anomalies of the bile ducts. They consist of cystic dilatations of the extrahepatic biliary ... Associated anomalies of the pancreatic duct, its junction with the common bile duct, and the long common channel formed by the ... In addition, small neoplasms of the gallbladder and bile duct may be missed. ... 21] They found that MRCP defined the proximal bile duct better than ERCP but that defects in the distal common bile duct were ...
Common Bile Duct. Multiple Myeloma / complications. Neoplasm Recurrence, Local. Pancreatic Neoplasms / complications ... Common Bile Duct Neoplasms / diagnosis. Common Bile Duct Neoplasms / drug therapy. Common Bile Duct Neoplasms / mortality. ... Bile Duct Neoplasms / pathology. Bile Ducts, Extrahepatic / pathology. Bile Ducts, Intrahepatic / pathology. Common Bile Duct ... MeSH-major] Bile Duct Neoplasms / diagnosis. Bile Duct Neoplasms / therapy. Bile Ducts, Extrahepatic. Bile Ducts, Intrahepatic ...
... bile duct (● Fig.3). The filling defect in the intrahepatic bile duct was considered to be mucin. Therefore, we diagnosed this ... examination showed a malignant papillary proliferation within the dilated B4 bile duct and invasion into the bile duct wall on ... this tumor causes cystic dilation of the affected bile ducts as well as branched-type intraductal mucinous papillary neoplasm ... We herein report the first case of an IPNB occurring in an extrahepatic site communicating with the intrahepatic bile duct. The ...
Bile ducts (1) Cancer (1) Common Bile Duct Neoplasms Pancreas Pancreatic Neoplasms (1) ... topic_facet:Common Bile Duct Neoplasms topic_facet:Pancreas institution:KU Medical Center ... Whipples procedure and operations for neoplasms of the pancreas, lower bile duct, and ampulla of Vater) / ... title: Pancreatic carcinomata. Includes index. Gift, no deed needed Advent Health [Shawnee...". Series: Single surgical ...
topic_facet:Common Bile Duct Neoplasms topic_facet:Pancreatic Neoplasms building:Clendening History of Medicine Library ( ... Bile ducts (1) Cancer (1) Common Bile Duct Neoplasms Pancreas (1) Pancreatic Neoplasms ... Whipples procedure and operations for neoplasms of the pancreas, lower bile duct, and ampulla of Vater) / ... Suggested Topics: Common Bile Duct Neoplasms * Suggested Topics: Pancreatic Neoplasms * Library: Clendening History of Medicine ...
... ductal obstruction of the pancreas or common bile duct (e.g. from neoplasm); and/or cystic fibrosis (an inherited disease in ... Pancreatic Exocrine Insufficiency (PEI) was induced in the minipigs by ligation of the pancreatic duct, and they were also ... In addition, 25 μl bile salts (80 mM Bile salts, bile salt mixture from Solvay Pharmaceuticals, batch 176.01-PA-7374, dissolved ... 1999): "Studies on nutrient digestibilities (pre-caecal and total) in pancreatic duct-ligated pigs and the effects of enzyme ...
Common Bile Duct Neoplasms/genetics*. *DNA Mutational Analysis. *Female. *Genetic Markers. *Germ-Line Mutation ... Germline mutation of STK11/LKB1 in patient PJS1 and loss of the wild-type allele of STK11/LKB1 in the pancreatic cancer of the ... A: PX68 (lanes 2) and PX68-1A (lanes 3) are two parallel xenografts of the same pancreatic cancer, and both exhibited the same ... Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers.. Su GH1, Hruban RH, ...
keywords = "3D imaging, Ampulla, Ampullary carcinoma, Common bile duct, CT, Pancreatic adenocarcinoma", ... The distal common bile duct (CBD) and ampulla are extremely difficult sites to evaluate on CT. This article seeks to provide ... The distal common bile duct (CBD) and ampulla are extremely difficult sites to evaluate on CT. This article seeks to provide ... The distal common bile duct (CBD) and ampulla are extremely difficult sites to evaluate on CT. This article seeks to provide ...
... clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinoma were found in PRIME PubMed. ... TumorCommon Bile Duct NeoplasmsDuodenal NeoplasmsFemaleHumansImmunohistochemistryMaleMiddle AgedMucinsPancreatic Neoplasms ... Intrapancreatic distal common bile duct carcinoma: Analysis, staging considerations, and comparison with pancreatic ductal and ... Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic ...
The Pancreaticobiliary Center treats complex pancreatic and biliary disorders including acute gallstone pancreatitis, acute ... Our experts treat conditions related to obstructive gallstones in the distal common bile duct and pancreatic duct, neoplasms ( ... Cholangiobiliary - Our experts treat obstructive gallstones in the common bile duct, common hepatic duct and cystic duct. ... pancreatic duct strictures, pancreatic pseudocysts, pancreatic walled-off necrosis (WON), extracorporeal shockwave lithotripsy ...
Pancreatic techniques for common bile duct cannulation in ERCP.. Gastrointest Endosc. 2019;90:168-169.. PubMed Text format June ... Intracholecystic papillary neoplasm of the gallbladder protruding into the common bile duct.. Gastrointest Endosc. 2018 Feb 23 ... Do we really need a fully covered self-expanding metal stent for the treatment of difficult common bile duct stones?. ... Comparative efficacy of various endoscopic techniques for the treatment of common bile duct stones: A network meta-analysis.. ...
Gallstone removal during ERCP from the common bile duct. First a generous sphincterotomy was performed and then the stones were ... PANCREATIC CANCER T4.... 17510 views ChristosKaralis. * 05:32. CYSTIC NEOPLASM OF THE.... 18020 views ChristosKaralis ... ERCP. Sphincterotomy. Ampulla Of Vater. Common Bile Duct Stones Removal. Christos Karalis. ... Gallstone removal during ERCP from the common bile duct. First a generous sphincterotomy was performed and then the stones were ...
Common Bile Duct Neoplasms/radiography/*surgery. Female. Follow-Up Studies. Humans. Male ... Pancreatic duct wire-guided endoscopic snare papillectomy for ampullary adenoma effectively facilitated pancreatic duct ... After resection, a pancreatic stent was immediately placed along or alongside the guide wire. RESULTS: Pancreatic duct stenting ... pancreatic duct stenting is important in preventing pancreatitis, but duct cannulation can be difficult following conventional ...
common (bile) duct. C24.0. C78.89. D01.5. D13.5. D37.6. D49.0. »cystic (bile) duct (common). C24.0. C78.89. D01.5. D13.5. D37.6 ... Benign neoplasm of liver and/or biliary ducts *Benign neoplasm of pancreatic duct ... Short Description: Benign neoplasm of extrahepatic bile ducts Long Description: Benign neoplasm of extrahepatic bile ducts This ... bile or biliary (tract). C24.9. C78.89. D01.5. D13.5. D37.6. D49.0. »bile or biliary (tract). »duct or passage (common) (cystic ...
Cecal Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis Colorectal Neoplasms, Common Bile Duct ... Jejunal Neoplasms, Liver Neoplasms, Experimental Liver Neoplasms, Pancreatic Neoplasms, Peritoneal Neoplasms, Rectal Neoplasms ... Bile Duct Neoplasms, Biliary Tract Neoplasms, Hepatocellular Carcinoma, Islet Cell Carcinoma, Pancreatic Ductal Carcinoma, ... Duodenal Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gardner Syndrome, Gastrinoma, Gastrointestinal Neoplasms, ...
... surgical management Evidence of surgical management of distal common bile duct cancer Evidence of surgical management of ... Who benefits from ultraradical pancreatic cancer resection? Risk and results of pancreatic cancer resection Pancreatic cancer: ... and radiologic presentation of pancreatic cancer Standards of oncologic pancreatic surgery Extended resection for pancreatic ... John Wiley & Sons (2015) ISBN 978-0-470-67318-8 Histologic classification and tumor staging of pancreatic cancer What we know ...
Common Bile Duct , Diagnosis , Humans , Liver Neoplasms , Mucins , Narrow Band Imaging , Pancreatic Neoplasms ... Bile Duct Neoplasms / Humans / Cholangiography / Cholangiopancreatography, Endoscopic Retrograde / Common Bile Duct / ... 11 bile duct cancers, 1 liver cancer, 1 pancreas cancer with common bile duct invasion). In 7 cases with papillary type tumor, ... Bile Duct Neoplasms , Cholangiography , Cholangiopancreatography, Endoscopic Retrograde , Cholangiopancreatography, Magnetic ...
Intraoperative cholangiogram revealed normal filling of the intrahepatic ducts, common hepatic duct, common bile duct, and ... No evidence of primary neoplasm was discovered at the time.. A CT scan on post-op day 9 (Figures 1 and 2) revealed a large, ... Genitourinary metastasis of pancreatic adenocarcinoma is exceedingly rare. Bladder metastases are far less common early in this ... 4 The most common manifestations of the urinary tract are ureteral obstruction and renal displacement.4 Hematuria in pancreatic ...
... common bile duct and a dilated main pancreatic duct in the absence of calculus suggests ampullary or pancreatic head neoplasm, ... an isolated pancreatic mass with or without dilatation of the bile and pancreatic ducts and combined bile-pancreatic duct ... The finding of a dilated main pancreatic duct in the body or tail but not in the head or neck suggests neoplasm, and finally, ... The primary finding on CT is a focal mass; however, if no mass is present, other findings may suggest neoplasm. First, the ...
Cholangitis Due to Pancreaticobiliary Fistula and Intraductal Papillary Mucinous Neoplasm: Thick Mucus Alters the Effectiveness ... CBD common bile duct; IDUS intraductal ultrasonography; IPMN intraductal papillary mucinous neoplasm; MPD main pancreatic duct ... Pancreaticobiliary fistulas connect the intrapancreatic portion of the common bile duct and the main pancreatic duct. Case ... Three endoscopic procedures were required because of failure to obtain effective common bile duct drainage due to stent ...
PancreasAdenocarcinomaDuctalAmpullaryMain pancPapillaryResectionAmpullaCancerDilatationTumorCancersBenignEndoscopic Retrograde CholangiopancLesionsJaundiceMalignanciesGallstonesCarcinomasMalignancyAcutePseudocystsCholangitisChronicDiagnosis of pancreaticNecrosisIncidenceGastrointestinalHepatic arterySurgeryAbdominal
- Another major indication for pancreatic resection is chronic pancreatitis, a condition associated with long-standing and progressive inflammation of the pancreas resulting in destruction and replacement of pancreatic tissue with fibrous tissue leading to exocrine pancreatic insufficiency and endocrine pancreatic insufficiency (diabetes) [ 13 ]. (hindawi.com)
- Not infrequently, because of its production of excess mucin, this tumor causes cystic dilation of the affected bile ducts as well as branched-type intraductal mucinous papillary neoplasm of the pancreas . (semanticscholar.org)
- Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas. (semanticscholar.org)
- In addition to endoscopic management of various obstructive gallstones in the common bile ducts, our providers also manage pancreatic duct leaks, pancreatitis secondary to pancreas divisum, pancreatic duct strictures, pancreatic pseudocysts, pancreatic walled-off necrosis (WON), extracorporeal shockwave lithotripsy (ESWL) for treatment for large pancreatic duct stones, and endoscopy ultrasound guided (EUS), pancreatic necrosectomy and placement of AXIOSTM stents for cystogastrostomy. (bannerhealth.com)
- Pancreaticobiliary - Our experts treat conditions related to obstructive gallstones in the distal common bile duct and pancreatic duct, neoplasms (growths) in the ampulla and head of the pancreas, neoplasms in the body and tail of the pancreas (benign or malignant growths), and pancreatitis secondary to gallstones, alcohol and other causes. (bannerhealth.com)
- Limited oncologic resection or major surgery for cystic neoplasms of the pancreas? (cancerlink.ru)
- Underlying diseases were all malignant in 13 patients (11 bile duct cancers, 1 liver cancer, 1 pancreas cancer with common bile duct invasion). (bvsalud.org)
- Context Fistula formation between the pancreas and adjacent organs has been reported in up to 6.6% of Intraductal papillary mucinous neoplasm cases of the pancreas. (imedpub.com)
- Case report Herein we report a case of an eighty-year-old man presented with a main pancreatic duct - intraductal papillary mucinous neoplasm complicated by PB fistula and obstructive cholangitis caused by the impaction of thick mucus protruding from the pancreas into the bile duct. (imedpub.com)
- Intraductal papillary mucinous neoplasms (IPMN) of the pancreas are increasingly recognized and currently account for 20% of resected pancreatic neoplasms. (imedpub.com)
- Herein we report a case of a MPD-IPMN complicated by PB fistula and obstructive cholangitis caused by the impaction of thick mucus protruding from the pancreas into the bile duct. (imedpub.com)
- The common hepatic duct and the cystic duct are regarded as the "bile ducts", which then enter the pancreas, merge with pancreatic duct, dilate to form the ampulla of Vater, pass through the sphincter of Oddi and enter the duodenum. (thefreedictionary.com)
- I get confused cause in some of her records it says it looks more like cholamgistis and it doesn't appear to be neoplasm in the head of the Pancreas. (cholangiocarcinoma.org)
- At presentation, the majority of periampullary tumours have grown to involve the pancreas, bile duct, ampulla and duodenum. (expertscape.com)
- Groove pancreatitis (GP) is a rare condition characterized by inflammatory fibrosis of the space between the dorsal-cranial part of the head of the pancreas, duodenum and common bile duct. (sciepub.com)
- An abdominal ultrasonography, a computer tomography (CT) and a gastro-duodenoscopy showed a mass of the pancreatic head with duodenal infiltration suggesting for adenocarcinoma of the pancreas. (sciepub.com)
- To review the CT and MR findings of a variety of cystic neoplasms of the pancreas and their histopathologic correlation of cases that have undergone surgery in our hospital. (netkey.at)
- Lymphoepithelial cysts of the pancreas: can common features avoid resection? (netkey.at)
- 2017) Diagnostic performance and imaging features for predicting the malignant potential of intraductal papillary mucinous neoplasm of the pancreas: a comparison of EUS, contrast-enhanced CT and MRI. (springer.com)
- Aetna considers pancreaticoduodenectomy (also known as Whipple resection) medically necessary for the treatment of intraductal papillary mucinous neoplasm of the pancreas (IPMN) with high-grade dysplasia or invasive cancer. (aetna.com)
- A 72 year-old Japanese woman showed remarkable dilatation of the main pancreatic duct (MPD) in the distal region of the pancreas. (biomedcentral.com)
- En bloc resection including the distal region of the pancreas, spleen, stomach and part of the transverse colon was performed under the pre- and intraoperative diagnosis of an invasive malignant IPMN. (biomedcentral.com)
- Intraductal papillary-mucinous neoplasms (IPMNs) of the pancreas have unique clinico-pathological characteristics and show a wide spectrum of histological types, ranging from adenomatous hyperplasia to invasive cancer. (biomedcentral.com)
- This procedure incidentally detected marked dilatation of the main pancreatic duct (MPD) in the distal region of the pancreas. (biomedcentral.com)
- Furthermore, the evaluation of the pancreas can be optimized by the use of MR pancreatography (MRP), which depicts the pancreatic ductal system, and with MR angiography (MRA), which visualizes the peripancreatic vessels. (appliedradiology.com)
- 9 It has been shown that the conspicuity of pancreatic tumors and the delineation of the pancreas from surrounding fat are best established on fat-suppressed T1W images. (appliedradiology.com)
- Intraductal tubular adenoma of the pancreas, pyloric gland type (ITA), is an infrequent intraductal benign lesion located in the main duct and large branch duct of the pancreas. (biomedcentral.com)
- In the 2010 edited WHO classification of digestive diseases, intraductal lesions of the pancreas were divided into two types: IPMNs and a new entity termed intraductal tubulopapillary neoplasms (ITPNs) [ 1 ]. (biomedcentral.com)
- She underwent laparoscopic pylorus preserving pancreaticoduodenectomy one year back for solid pseudopapillary neoplasm of head of pancreas. (sages.org)
- Pancreatic cancer refers to a malignant neoplasm of the pancreas. (addexbio.com)
- The most common type of pancreatic cancer, accounting for 95% of these tumors is adenocarcinoma, which arises within the exocrine component of the pancreas. (addexbio.com)
- Ultrasound was highly sensitive (93%) in the detection of the primary tumour in the bile duct or pancreas, or in the visualization of nodal or liver metastases. (elsevier.com)
- Preoperative diagnosis of pancreatic schwannoma is challenging due to its tendency to mimic other lesions of the pancreas. (biomedcentral.com)
- This rare case shows that the ectopic pancreas might have caused penetration of jejunal diverticulum owing to the pancreatic duct opening through the diverticulum. (springermedizin.de)
- The expert shares broad information regarding Cystic neoplasms of the pancreas: categories, symptoms, diagnosis, treatment, risks and outcomes, and qualifications for performing surgery on the pancreas. (doctorsmedicalopinion.com)
- A patient with a cystic neoplasm of the pancreas refers the expert various questions regarding his condition. (doctorsmedicalopinion.com)
- Cystic neoplasms of the pancreas are uncommon but confusing diagnostic problems that are being encountered with greater frequency. (doctorsmedicalopinion.com)
- Cystic neoplasms of the pancreas can be classified into four major categories. (doctorsmedicalopinion.com)
- Recent studies on small series of pancreatic cancer (PC) with foci of pancreatic intraepithelial neoplasia (PanIN), a putative precursor lesion, have shown that multiple K-RAS mutations may coexist in the same neoplastic pancreas. (nih.gov)
- Intraductal papillary mucinous neoplasms (IPMN) are mucin producing cystic neoplasms of the pancreas. (sages.org)
- Cystic neoplasms of the pancreas are being increasingly identified, due to the increased use of cross sectional imaging like CT or MRI. (psychiatryadvisor.com)
- The understanding of IPMN of the pancreas has evolved from the "mucin producing pancreatic tumor" with epithelial dysplasia to a new nomenclature with definitions encompassing specific clinical, radiologic, historical and genetic aspects of the disease. (psychiatryadvisor.com)
- In the absence of a history of pancreatitis, a cyst seen in or on the pancreas should be considered a cystic neoplasm until proven otherwise. (psychiatryadvisor.com)
- Nearly 50% of the bile flows into the cystic duct and is then stored in the gallbladder with the rest of the bile flowing through the common bile duct and converging and flowing through the main pancreatic duct in the head of the pancreas to empty into the duodenum through the sphincter of Oddi. (statpearls.com)
- Background: Pancreatitis and jaundice secondary to ductal obstruction are common in intraductal papillary mucinous tumors (IPMT) of the pancreas. (elsevier.com)
- Purpose Malignant tumors of the common bile duct or of the pancreas head are uncommon in childhood [Perez EA, Gutierrez JC, Koniaris LG, Neville HL, Thompson WR, Sola JE. (elsevier.com)
- With radical surgery being the standard cure for nonmetastatic diseases, pancreaticoduodenectomy (PD) is the best choice when the tumor is localized in the head of the pancreas, or in the lower portion of the common bile duct. (elsevier.com)
- Biliary and pancreatic duct strictures are most often caused by inflammatory or neoplastic disorders involving the pancreas, biliary tree, gallbladder, or ampulla. (bmj.com)
- 1 Family Practice Oncology Network Upper Gastrointestinal Cancer (Suspected) Part 2 External Review Effective Date: TBD SCOPE: Part 2 of this guideline outlines recommendations for the prevention, screening, diagnosis, treatment and follow-up of upper gastrointestinal (GI) malignancies, ncluding pancreatic cancer, neuroendocrine tumours (NETs) of the pancreas and duodenum, and cancer of the extrahepatic biliary tract. (docplayer.net)
- The findings were consistent with moderately differentiated metastatic pancreatic adenocarcinoma. (appliedradiology.com)
- Resected tumor specimen revealed metastatic pancreatic adenocarcinoma with extensive submucosal and muscularis involvement. (appliedradiology.com)
- 8 The most common pancreatic diseases (ie, pancreatitis and pancreatic adenocarcinoma) have longer T1 because of increased free water protons and, therefore, have lower signal intensity compared with that of the surrounding normal pancreatic parenchyma. (appliedradiology.com)
- Loss of heterozygosity predicts poor survival after resection of pancreatic adenocarcinoma. (cdc.gov)
- American Joint Committee on Cancer (AJCC) staging for pancreatic adenocarcinoma is a validated predictor of prognosis but insufficiently discriminates postresection survival. (cdc.gov)
- Ductal adenocarcinoma is by far the most common periampullary malignant tumor. (springer.com)
- Some lesions present in a similar fashion to pancreatic adenocarcinoma with obstructive jaundice due to impingement of the bile duct. (doctorsmedicalopinion.com)
- To describe CT characteristics of primary pancreatic lymphoma (PPL), a rare disease with features in common with adenocarcinoma. (readbyqxmd.com)
- Pancreatic adenocarcinoma has a poor prognosis. (radiologyassistant.nl)
- The majority of pancreatic cancers (85%) are adenocarcinoma of ductal origin. (radiologyassistant.nl)
- This study will assess the efficacy and safety of BL-8040 in combination with pembrolizumab (Keytruda®) and BL8040/ Pembrolizumab in combination with liposomal irinotecan ( Onivyde® )/5-fluorouracil/leucovorin (5-FU/LV) in subjects with metastatic pancreatic adenocarcinoma. (clinicaltrials.gov)
- This will be an open-label, two-cohort, phase IIa study in subjects with metastatic pancreatic adenocarcinoma. (clinicaltrials.gov)
- Each includes approximately 40 subjects with unresectable metastatic pancreatic adenocarcinoma. (clinicaltrials.gov)
- Cohort 1: Subjects with metastatic pancreatic adenocarcinoma will be enrolled and receive BL-8040 monotherapy for five days followed by a combination treatment of BL-8040 and pembrolizumab. (clinicaltrials.gov)
- Cohort 2: Subjects with metastatic pancreatic adenocarcinoma that have progressed following first-line treatment with gemcitabine-based chemotherapy will be enrolled and receive BL-8040 monotherapy for five days followed by a combination treatment of BL-8040, pembrolizumab and chemotherapy. (clinicaltrials.gov)
- Ampullary cancers have a better prognosis than pancreatic adenocarcinoma. (docplayer.net)
- Resected pancreatic ductal and ampullary adenocarcinomas (n = 50) were analyzed for loss of heterozygosity (LOH) at 15 markers including 5q(APC), 6q(TBSP2), 9p(p16), 10q(PTEN), 12q(MDM2), 17p(TP53), and 18q(DCC/SMAD4). (cdc.gov)
- LOH and KRAS mutations indicate aggressive tumor biology and correlate strongly with survival in resected pancreatic ductal and ampullary carcinomas. (cdc.gov)
- An adenoma component common in ampullary-duodenal cancers was noted in only about a third. (unboundmedicine.com)
- PATIENTS AND METHODS: Pancreatic duct wire-guided endoscopic papillectomy was performed in 72 patients with ampullary adenoma. (indexmedicine.com)
- CONCLUSIONS: Pancreatic duct wire-guided endoscopic snare papillectomy for ampullary adenoma effectively facilitated pancreatic duct stenting to prevent severe post-procedure pancreatitis. (indexmedicine.com)
- The presence of both a dilated common bile duct and a dilated main pancreatic duct in the absence of calculus suggests ampullary or pancreatic head neoplasm, but this may also be seen in benign disease. (uab.edu)
- Periampullary cancers include pancreatic, ampullary, biliary and duodenal cancers. (expertscape.com)
- Patients with resected duodenal and ampullary cancers have a better reported median survival (29-47 mo and 22-54 mo) compared to pancreatic cancer (13-19 mo). (expertscape.com)
- To see whether mutant-K-RAS polyclonality is a common and specific feature of pancreatic carcinogenesis, we investigated a unselected series of periampullary cancers (41 pancreatic, 13 biliary and two ampullary adenocarcinomas). (nih.gov)
- Pancreaticobiliary fistulas connect the intrapancreatic portion of the common bile duct and the main pancreatic duct. (imedpub.com)
- Pancreaticobiliary fistulas (PB) connect the intrapancreatic portion of the CBD and the main pancreatic duct (MPD). (imedpub.com)
- Endoscopic therapy for main pancreatic duct rupture after silastic-ring vertical gastroplasty. (springermedizin.de)
- A previously undescribed form of intraductal papillary neoplasm of the bile duct. (semanticscholar.org)
- Intraductal papillary neoplasm of the bile duct (IPNB) is characterized by dilated intrahepatic bile ducts filled with papillary or villous neoplastic biliary epithelium . (semanticscholar.org)
- Non-invasive intraductal papillary neoplasms of the common bile duct: a clinicopathologic study of six cases. (semanticscholar.org)
- A surgical approach was then decided to treat both persistent obstructive jaundice and the intraductal papillary mucinous neoplasm. (imedpub.com)
- Pancreatic cystic lesions comprise a variety of categories including benign inflammatory and non-inflammatory conditions (pseudocyst or neoplasm such as serous cystadenoma -SCN-), premalignant like mucinous cystic neoplasia (MCN) and papillary intraductal mucinous neoplasia (IPMN) and malignant , as in the case of cystadenocarcinoma with cystic degeneration. (netkey.at)
- Among premalignant lesions we have IPMN intraductal papillary mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN). (netkey.at)
- Fistula formation has been reported in intraductal papillary-mucinous neoplasms (IPMNs) with or without invasion of the adjacent organs. (biomedcentral.com)
- Aoki Y, Mizuma M, Hata T, Aoki T, Omori Y, Ono Y, Mizukami Y, Unno M, Furukawa T. Intraductal papillary neoplasms of the bile duct consist of two distinct types specifically associated with clinicopathological features and molecular phenotypes. (harvard.edu)
- The purpose of this report is to introduce seven new cases and to compare their clinicopathologic features and KRAS mutations to gastric-type intraductal papillary mucinous neoplasms (IPMNs) and intraductal tubulopapillary neoplasms (ITPNs). (biomedcentral.com)
- Clinical findings, morphologic features, immunophenotypes and KRAS alterations were investigated in 7 patients with intraductal tubular adenomas, 16 patients with gastric-type intraductal papillary mucinous neoplasms and 6 patients with intraductal tubulopapillary neoplasms. (biomedcentral.com)
- ITPNs were polypoid and papillary mass located in the pancreatic ducts, which did not show large deposits of mucin. (biomedcentral.com)
- The term of intraductal papillary mucinous neoplasm (IPMN) has traditionally been used to describe them, and it is widely recognized. (biomedcentral.com)
- Endoscopic papillary balloon dilation (EPBD) and endoscopic papillary large balloon dilation (EPLBD) have been performed all around the world over several decades for the treatment of common bile duct stone. (kjpbt.org)
- Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with intraductal papillary neoplasms of the bile duct. (thefreedictionary.com)
- The diagnosis of solid and papillary epithelial neoplasm carries an excellent prognosis with surgical resection. (thefreedictionary.com)
- A systematic review of Medline, Embase, and the Cochrane library was performed to identify studies on pancreatic resection including at least 100 patients and published between 2004 and 2014. (hindawi.com)
- Pancreatic resection is one of the most common major operative procedures performed by Hepato-Pancreato-Biliary (HPB) surgeons. (hindawi.com)
- The major indication for pancreatic resection is pancreatic cancer, the seventh most common cause of cancer-related mortality in the world, resulting in approximately 330 000 deaths worldwide annually [ 1 ]. (hindawi.com)
- In early pancreatic cancer (with no invasion of adjacent structures such as the superior mesenteric vein, portal vein, or superior mesenteric artery or distal metastases), surgical resection is generally considered the only treatment with the potential for long-term survival and possibility of cure in people likely to withstand major surgery. (hindawi.com)
- However, it should be noted that about half of the patients presenting with pancreatic cancer will have metastatic disease and one-third have locally advanced unresectable disease, leaving about 10% to 20% suitable for resection [ 12 ]. (hindawi.com)
- BACKGROUND AND STUDY AIMS: After endoscopic papillectomy, pancreatic duct stenting is important in preventing pancreatitis, but duct cannulation can be difficult following conventional snare resection. (indexmedicine.com)
- Pancreatic duct wire-guided endoscopic snaring before resection can reduce the post-procedure stenting failure rate. (indexmedicine.com)
- After resection, a pancreatic stent was immediately placed along or alongside the guide wire. (indexmedicine.com)
- Who benefits from ultraradical pancreatic cancer resection? (cancerlink.ru)
- Unfortunately, most of those who undergo resection eventually die of pancreatic cancer. (uab.edu)
- This larger size at presentation contributes to a higher incidence of resection margin involvement in pancreatic cancer. (expertscape.com)
- In spite of the limited tumor size the majority of pancreatic head cancers (80%) are not eligible for resection at the time of diagnosis. (radiologyassistant.nl)
- In two cases, PD was performed en bloc with a right hepatectomy in order to achieve the radical resection of a recurrent biliary sarcoma. (elsevier.com)
- The distal common bile duct (CBD) and ampulla are extremely difficult sites to evaluate on CT. (elsevier.com)
- In our experience, both the distal CBD and ampulla are common sites of missed diagnoses for radiologists. (elsevier.com)
- Raman, SP & Fishman, EK 2014, ' Abnormalities of the distal common bile duct and ampulla: Diagnostic approach and differential diagnosis using multiplanar reformations and 3D imaging ', American Journal of Roentgenology , vol. 203, no. 1, pp. 17-28. (elsevier.com)
- They are anatomically classified as intrahepatic (arising proximal to the second order bile ducts), perihilar (arising between the second order bile ducts and the insertion of the cystic duct into the common bile duct) and distal extrahepatic (arising between the insertion of the cystic duct and the ampulla of Vater) [ 2 ]. (biomedcentral.com)
- Pancreatic cancer is a biologically aggressive cancer, which is relatively resistant to chemotherapy and radiotherapy and has a high rate of local and systemic recurrence [ 2 - 4 ]. (hindawi.com)
- Less appreciated is the fact that PJS also predisposes patients to an increased risk of gastrointestinal cancer, and pancreatic cancer has been reported in many PJS patients. (nih.gov)
- We investigated the role of STK11/LKB1 in the development of pancreatic and biliary cancer in patients with and without the PJS. (nih.gov)
- In a PJS patient having a germline splice site mutation in the STK11/LKB1 gene, sequencing analysis of an intestinal polyp and pancreatic cancer from this patient revealed loss of the wild-type allele of the STK11/LKB1 gene in the cancer. (nih.gov)
- Germline mutation of STK11/LKB1 in patient PJS1 and loss of the wild-type allele of STK11/LKB1 in the pancreatic cancer of the same patient. (nih.gov)
- CFPAC1 ( lanes 1 ) and two pancreatic cancer xenografts ( lanes 3 and 4 ) exhibited normal sequences. (nih.gov)
- Detection of homozygous deletions in the genomic DNAs of pancreatic cancer xenograft PX30 and biliary cancer xenograft PX115 by duplex PCR using pairs of internal control primers (INTB4-B or MKK4-E) and STK11/LKB1 -specific primers. (nih.gov)
- Risk/benefit of total pancreatectomy for pancreatic cancer: are there indications? (cancerlink.ru)
- Neoadjuvant chemotherapy and radiochemotherapy: is there a survival advantage for pancreatic cancer patients? (cancerlink.ru)
- Pancreatic cancer is the fourth-leading cause of death in the USA among men and women. (appliedradiology.com)
- This almost uniformly fatal cancer is the 4th most common malignant tumor accounting for 5% of cancer deaths in the United States. (uab.edu)
- It has been demonstrated that mucins, specifically MUC4, are overexpressed in pancreatic cancer. (sbirsource.com)
- Furthermore, we have recently showed that SERS-based nano-immunoassay is capable of differentiating samples of control cases from those of pancreatic cancer patients. (sbirsource.com)
- The clinical utility of the assay will be validated (Aim 2) by comparing the assay with the PC prognostic marker CA19.9 and clinically testing the SERS-based assay in high risk controls and pancreatic cancer patients samples. (sbirsource.com)
- The poorer survival with pancreatic cancer relates to differences in tumour characteristics such as a higher incidence of nodal, neural and vascular invasion. (expertscape.com)
- Nonsteroidal anti-inflammatory drugs, statins, and pancreatic cancer risk: a population-based case-control study. (expertscape.com)
- However, findings have been conflicting as to whether these agents reduce the risk of pancreatic cancer. (expertscape.com)
- METHODS: We used data from the Queensland Pancreatic Cancer Study, a population-based case-control study. (expertscape.com)
- Unconditional multivariable logistic regression was used to estimate associations between medication use and pancreatic cancer. (expertscape.com)
- RESULTS: We found no consistent evidence of an association between use of NSAIDs or statins and risk of pancreatic cancer. (expertscape.com)
- Monitoring tumor burden in response to FOLFIRINOX chemotherapy via profiling circulating cell-free DNA in pancreatic cancer. (cdc.gov)
- The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21205. (expertscape.com)
- Pancreatic Cancer Translational Center of Excellence, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104. (expertscape.com)
- High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study. (expertscape.com)
- Pancreatic cancer is among the most lethal cancers with poorly tolerated treatments. (expertscape.com)
- Here, we further revealed its anti-pancreatic cancer mechanisms and conducted a phase I/IIa study to investigate pharmacokinetic interaction between IVC and gemcitabine. (expertscape.com)
- Pharmacological ascorbate induced cell death in pancreatic cancer cells with diverse mutational backgrounds. (expertscape.com)
- The surgical oncologists at the Center for Advanced Surgical Oncology are specially trained in common and complex cancer surgery utilizing some of the latest technology. (tenetfloridaphysicianservices.com)
- Cancer deaths were identified using underlying cause-of-death codes C00-C97 (malignant neoplasms). (cdc.gov)
- 27,959 people died of liver and intrahepatic bile duct cancer (9,267 females and 18,692 males). (cdc.gov)
- These features are often associated with high bile acid exposure and may explain the association of dietary-related factors with cancer progression. (nih.gov)
- Fistula formation without cancer spread could be linked to a combination of high pressure in the pancreatic duct and ongoing chronic inflammation. (sages.org)
- Pancreatic mucinous cystic neoplasm defined by ovarian stroma: demographics, clinical features, and prevalence of cancer. (thefreedictionary.com)
- 4 , 5 Percutaneous radiologically guided fine needle aspiration (FNA) is a very accurate technique, particularly in the diagnosis of pancreatic cancer, but is operator dependent and requires a sufficiently distinct mass lesion for targeting. (bmj.com)
- If pancreatic cancer is suspected, investigations should be expedited. (docplayer.net)
- 3,4 Excessivee alcohol consumption, as well as the presence of diabetes and chronic pancreatitis increase the risk of pancreatic cancer. (docplayer.net)
- SCREENING Theree are no recommended screening guidelines for pancreatic or bile duct cancer. (docplayer.net)
- 2,5 The incidence of these cancers is low (e.g. the incidence of pancreatic cancer in B.C. is cases per population, and bile duct cancer 1-2 cases perr population). (docplayer.net)
- 6,7 Screening with EUS or MRI may be indicated in patients at high risk (seee Risk Factors) for pancreatic cancer. (docplayer.net)
- 5,8 Risk Factors The incidence of pancreatic cancer increases significantlyy from the age of Non-hereditary and Helicobacter pylori infection. (docplayer.net)
- 3 Hereditary pancreatic cancer account forr 5-10% of cases. (docplayer.net)
- 9 Bile duct cancer occurs equally in men and women, and incidence peaks in the sixth and seventh decade. (docplayer.net)
- 10 DIAGNOSIS Pancreatic Cancer Pancreatic cancers are of exocrine or endocrine origin. (docplayer.net)
- In pancreatic cancer, the two most common presenting symptoms are abdominal pain and jaundice. (docplayer.net)
- 15 Other non-specific symptoms are included below: Painless jaundice is considered to be pancreatic cancer until proven otherwise. (docplayer.net)
- Signs of potential resectability include an isolated pancreatic mass with or without dilatation of the bile and pancreatic ducts and combined bile-pancreatic duct dilatation without an identifiable pancreatic mass. (uab.edu)
- Computed tomography of the upper abdomen showed dilatation of the intrahepatic bile duct, CBD, and MPD without evidence of pancreatic head mass. (imedpub.com)
- in patients with cholestasis syndrome, on noticed dilatation of the intra- and extrahepatic bile ducts, along with dilatation of Wirsung's duct (Fig. 1a). (nih.gov)
- In patients with a pancreatic head tumor, typically dilatation of the common bile duct and pancreatic duct (double duct sign) is seen, which is very suggestive for a mass in the pancreatic head, even in the absence of a visible mass. (radiologyassistant.nl)
- What is the place of interventional endoscopic treatment in chronic pancreatitis with inflammatory tumor of the pancreatic head? (cancerlink.ru)
- They may include abdominal pain and jaundice (if the tumor compresses the bile duct). (addexbio.com)
- Pancreatic schwannoma is a rare tumor. (biomedcentral.com)
- Pathological examination showed that the tumor was composed of spindle cells with a palisading arrangement, and immunohistochemistry revealed strong positive staining for S-100 protein, which was consistent with a diagnosis of pancreatic schwannoma. (biomedcentral.com)
- On contrast-enhanced CT, there was mild and heterogeneous enhancement in the solid component of the tumor, which was less than the surrounding pancreatic parenchyma. (biomedcentral.com)
- CT is the method of choice for an accurate staging of small bowel neoplasm, in order to assess the locoregional extent, the presence of lymphoadenopaty, vascular invasion and distant metastatic desease.Instead , MRCP can help to characterized better the tumor through the analysis of intensity signal and is useful particularly in lesions involving biliary tract thanks to its three-dimensional reconstruction by using a maximum-intensity projection(MIP) algorithm. (eurorad.org)
- Non-resectable pancreatic head tumor obstructing the common bile duct and pancreatic duct. (radiologyassistant.nl)
- When the tumor proves to be unresectable during exploratory laparotomy, a so-called 'double bypass' (gastro-enterostomy en hepaticojejunostomy) is usually performed for palliative reasons. (radiologyassistant.nl)
- LEFT: small liver lesion with typical appearance of metastasisRIGHT: Hypoechoic pancreatic head tumor obstructing pancreatic duct. (radiologyassistant.nl)
- Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. (nih.gov)
- Duplex PCR analysis of homozygous deletions in pancreatic and biliary cancers. (nih.gov)
- EUS uses miniaturized ultrasound probes inserted into the bile duct or the upper and lower gastrointestinal tract to provide detailed images that aid in the diagnosis of HPB conditions as well as the staging of patients with esophageal, gastric and rectal cancers. (ohsu.edu)
- Common occurrence of multiple K-RAS mutations in pancreatic cancers with associated precursor lesions and in biliary cancers. (nih.gov)
- K-RAS codon 12 was mutated in 34 (83%) pancreatic cancers and in 11 (85%) biliary cancers. (nih.gov)
- KEY RECOMMEND DATIONS Screening for upper GI cancers, including extrahepatic biliary and pancreatic cancers, is not recommended. (docplayer.net)
- For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. (icdlist.com)
- Hemangiomas are the most common benign lesion with incidence reported as high as 20% in the general population. (radiologykey.com)
- Intrahepatic duct dilation was present in 93% of malignant strictures versus 36% of benign strictures (P = 0.002). (elsevier.com)
- However, how to distinguish malignant from benign pancreatic schwannomas remains challenging. (biomedcentral.com)
- They account for fewer than 10% of all pancreatic malignancies, but up to 30% of pancreatic resections performed, and they encompass a spectrum of benign, premalignant (borderline) and malignant lesions. (doctorsmedicalopinion.com)
- Although they are less common, it is important to distinguish cystic neoplasms from the far more prevalent entity of benign pseudocysts, which are usually associated with a clinical history and radiographic evidence of pancreatitis. (doctorsmedicalopinion.com)
- Serous Cystadenoma , the most common classification, is a distinctly benign lesion characterized by a glycogen-rich epithelial lining. (doctorsmedicalopinion.com)
- Differentiating benign from malignant pancreatic cystic lesions remains a challenging task. (psychiatryadvisor.com)
- One hundred and sixty patients (39.4%) had benign strictures, most often as a result of chronic pancreatitis and bile duct stones. (bmj.com)
- Pancreatic cystic lesions: easy drawing for differentiation of pancreatic cysts. (netkey.at)
- Cystic pancreatic lesions are increasingly detected because of the improvement of CT and MR diagnostic techniques. (netkey.at)
- To evaluate pancreatic lesions accurately, the use of multiple pulse sequences that provide complementary information is required, and, in general, a combination of T1-weighted (T1W) and T2-weighted (T2W) sequences is obtained. (appliedradiology.com)
- An abdominal ultrasonography showed a global heterogeneous echogenicity of the pancreatic gland without other focal lesions.An endoscopic ultrasonographic examination(EUS)demonstrated an irregular, dysomogeneous echogenic lesion with central hyperechoic spots due to necrotic areas, involving the duodenal wall, probably arising from pancreatic head. (eurorad.org)
- Biliary and pancreatic duct lesions are not always readily accessible to biopsy, and cytological techniques have become the initial diagnostic modality in many cases. (bmj.com)
- The most striking clinical symptom leading to diagnostic imaging is painless obstructive jaundice, which is caused by compression or ingrowth of the distal common bile duct. (radiologyassistant.nl)
- However, the patient with pancreaticobiliary fistula had obstructive jaundice with repeated episodes of cholangitis due to continuous thick mucous plugging of the common bile duct. (sages.org)
- Stents were put into the ducts for decompression and drainage on several occasions to relieve obstructive jaundice. (sages.org)
- Painless jaundice should be considered to be pancreatic cancerr until proven otherwise. (docplayer.net)
- Cholangiobiliary - Our experts treat obstructive gallstones in the common bile duct, common hepatic duct and cystic duct. (bannerhealth.com)
- Even though the organ is small, it is a common cause of abdominal pain due to gallstones, which often require surgical removal of the organ. (statpearls.com)
- Gallstones are a common cause of right upper quadrant calcification, despite the fact that only a minority contain enough calcium making them visible on X-ray. (radiologykey.com)
- Cholelithiasis (gallstones) occurs as a result of supersaturation of bile with cholesterol (70%), pigments such as bilirubin (20%), or both (10%) combined with delayed emptying of the gallbladder (stasis). (saem.org)
- Choledocholithiasis refers to the presence of gallstones within the common bile duct. (saem.org)
- Common bile duct stones (CBDS) are estimated to be present in 10-20% of individuals with symptomatic gallstones. (kjpbt.org)
- She was found to have gallstones with dilation of the common bile duct with a concern for choledocholithiasis, without evidence of cholecystitis and pneumoperitoneum specious for perforated peptic ulcer. (scirp.org)
- A CT scan showed splenomegaly, locally invasive pancreatic tail malignancy involving the adjacent splenic flexure and perirenal fascia of the kidney (Figure 7). (appliedradiology.com)
- To analize the different forms of pancreatic cystic neoplasms and their potential for malignancy. (netkey.at)
- HCC is the most common visceral malignancy in the world. (radiologykey.com)
- Hemodynamic instability occurred due to abdominal hemorrhage from two pseudoaneurysms inside an acute peri-pancreatic collection. (elsevier.es)
- Differentiating a choledochal cyst from a hepatic cyst, hepatic abscess, acute fluid collection, or pancreatic pseudocyst may be difficult. (medscape.com)
- Baron TH, Harewood GC, Morgan DE, Yates MR. Outcome differences after endoscopic drainage of pancreatic necrosis, acute pancreatic pseudocysts, and chronic pancreatic pseudocysts. (springermedizin.de)
- Bacteriological analysis of bile in acute cholecystitis according to the Tokyo guidelines. (semanticscholar.org)
- Histologic examination confirmed chronic inflammation in the groove area with a ruptured pancreatic-type cyst and some pseudocysts in depth of the wall. (sciepub.com)
- Baillie J. Pancreatic pseudocysts (part I). Gastrointest Endosc. (springermedizin.de)
- The natural history of pancreatic pseudocysts documented by computed tomography. (springermedizin.de)
- The natural history of pancreatic pseudocysts: a unified concept of management. (springermedizin.de)
- Cholangitis is inflammation of the bile ducts and is most often caused by a polymicrobial bacterial infection. (saem.org)
- Cholangitis is an inflammation of the bile ducts. (psychiatryadvisor.com)
- Ascending cholangitis occurs when bacterial infection is superimposed on bile stasis from impeded bile drainage. (psychiatryadvisor.com)
- The presence of predisposing conditions causing bile duct stasis or biliary manipulation is necessary for cholangitis. (psychiatryadvisor.com)
- The technique and review of current literature regarding endoscopic therapy of pancreatic necrosis and abscess will be discussed. (springermedizin.de)
- Endoscopic therapy for organized pancreatic necrosis. (springermedizin.de)
- Baron T. Endoscopic drainage of pancreatic fluid collections and pancreatic necrosis. (springermedizin.de)
- Aggressive endoscopic therapy for pancreatic necrosis and pancreatic abscess: a new safe and effective treatment algorithm (videos). (springermedizin.de)
- Of these, about 30% develop infected pancreatic necrosis requiring intervention. (mhmedical.com)
- The evidence to enable a recommendation about antibiotic prophylaxis against infection of pancreatic necrosis is conflicting and difficult to interpret. (bmj.com)
- Post-surgical upper gastrointestinal anatomy may hamper a complete bilio-pancreatic evaluation with a standard echoendoscope. (springer.com)
- The most frequently reported adverse reactions to pancreatic enzyme-containing products are gastrointestinal in nature which may include nausea , vomiting, bloating, cramping, constipation or diarrhea . (rxlist.com)
- ConclusionEctopic biliary drainage into the stomach is extremely rare, but its recognition may help identify the cause of certain clinical conditions and prevent bile duct injury during surgery if required. (medworm.com)
- Journal of Hepato-Biliary-Pancreatic Surgery , 9 (5), 627-631. (elsevier.com)
- These small vessels must be preserved during surgery to ensure adequate perfusion of the cystic and common bile ducts. (statpearls.com)
- After pancreaticoduodenectomy surgery hepaticojejunostomy (HJ) stricture is a rare condition and seen in undilated ducts. (sages.org)