AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceNamed GroupsHealth Care
Pancreas TransplantationPancreasKidney TransplantationGraft SurvivalGraft RejectionPancreatitis, GraftIslets of Langerhans TransplantationTransplantation, HomologousDiabetes Mellitus, Type 1Liver TransplantationTissue DonorsImmunosuppressionImmunosuppressive AgentsOrgan PreservationTacrolimusBone Marrow TransplantationTissue and Organ ProcurementDiabetic NephropathiesPostoperative ComplicationsHematopoietic Stem Cell TransplantationActuarial AnalysisWaiting ListsHeart TransplantationTreatment OutcomeTransplantation, AutologousLung TransplantationPortal VeinTime FactorsDrainageRetrospective StudiesInsulinStem Cell TransplantationC-PeptideDuodenumTransplantation ConditioningMycophenolic AcidOrgan TransplantationCyclosporineFollow-Up StudiesSurvival RateBlood GlucoseTransplantationTransplantation ImmunologyDiabetes MellitusCell TransplantationDiabetes Mellitus, ExperimentalTransplantation ChimeraPancreas, ExocrineHemoglobin A, Glycosylated
Pancreas Transplantation
The transference of a pancreas from one human or animal to another.
Pancreas
A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
Kidney Transplantation
The transference of a kidney from one human or animal to another.
Graft Survival
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
Graft Rejection
An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.
Pancreatitis, Graft
An inflammatory disease and serious complication of PANCREAS TRANSPLANTATION. It is caused by a premature activation of pancreatic proenzymes leading to autodigestion of the gland and can be attributed to immunological or nonimmunological causes.
Islets of Langerhans Transplantation
The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.
Transplantation, Homologous
Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals.
Diabetes Mellitus, Type 1
A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Liver Transplantation
The transference of a part of or an entire liver from one human or animal to another.
Tissue Donors
Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.
Immunosuppression
Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Organ Preservation
The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Tacrolimus
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Bone Marrow Transplantation
The transference of BONE MARROW from one human or animal to another for a variety of purposes including HEMATOPOIETIC STEM CELL TRANSPLANTATION or MESENCHYMAL STEM CELL TRANSPLANTATION.
Tissue and Organ Procurement
The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.
Diabetic Nephropathies
KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
Postoperative Complications
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Hematopoietic Stem Cell Transplantation
Transfer of HEMATOPOIETIC STEM CELLS from BONE MARROW or BLOOD between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Hematopoietic stem cell transplantation has been used as an alternative to BONE MARROW TRANSPLANTATION in the treatment of a variety of neoplasms.
Actuarial Analysis
The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
Waiting Lists
Prospective patient listings for appointments or treatments.
Heart Transplantation
The transference of a heart from one human or animal to another.
Treatment Outcome
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Transplantation, Autologous
Transplantation of an individual's own tissue from one site to another site.
Lung Transplantation
The transference of either one or both of the lungs from one human or animal to another.
Portal Vein
A short thick vein formed by union of the superior mesenteric vein and the splenic vein.
Time Factors
Elements of limited time intervals, contributing to particular results or situations.
Drainage
The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Stem Cell Transplantation
The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.
C-Peptide
The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
Duodenum
The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
Transplantation Conditioning
Preparative treatment of transplant recipient with various conditioning regimens including radiation, immune sera, chemotherapy, and/or immunosuppressive agents, prior to transplantation. Transplantation conditioning is very common before bone marrow transplantation.
Mycophenolic Acid
An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)
Organ Transplantation
Transference of an organ between individuals of the same species or between individuals of different species.
Cyclosporine
A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Follow-Up Studies
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Survival Rate
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Blood Glucose
Glucose in blood.
Transplantation
Transference of a tissue or organ from either an alive or deceased donor, within an individual, between individuals of the same species, or between individuals of different species.
Transplantation Immunology
A general term for the complex phenomena involved in allo- and xenograft rejection by a host and graft vs host reaction. Although the reactions involved in transplantation immunology are primarily thymus-dependent phenomena of cellular immunity, humoral factors also play a part in late rejection.
Diabetes Mellitus
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Cell Transplantation
Transference of cells within an individual, between individuals of the same species, or between individuals of different species.
Diabetes Mellitus, Experimental
Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by PANCREATECTOMY.
Transplantation Chimera
An organism that, as a result of transplantation of donor tissue or cells, consists of two or more cell lines descended from at least two zygotes. This state may result in the induction of donor-specific TRANSPLANTATION TOLERANCE.
Pancreas, Exocrine
The major component (about 80%) of the PANCREAS composed of acinar functional units of tubular and spherical cells. The acinar cells synthesize and secrete several digestive enzymes such as TRYPSINOGEN; LIPASE; AMYLASE; and RIBONUCLEASE. Secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the DUODENUM.
Hemoglobin A, Glycosylated
Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.

Detection of Epstein-Barr virus DNA in sera from transplant recipients with lymphoproliferative disorders. (1/501)

Early diagnosis of Epstein-Barr Virus (EBV)-associated posttransplant lymphoproliferative disease (PTLD) is important because many patients respond to reduction in immunosuppression, especially if PTLD is detected at an early stage. Previous studies have found elevated EBV DNA levels in blood from patients with PTLD, but these assays required isolation of cellular blood fractions and quantitation. We evaluated the presence of cell-free EBV DNA in serum from solid-organ transplant recipients as a marker for PTLD. Five of 6 transplant recipients with histopathologically documented PTLD had EBV DNA detected in serum at the time of diagnosis (sensitivity = 83%), compared with 0 of 16 matched transplant recipients without PTLD (specificity = 100%) (P < 0.001 [Fisher's exact test]). Furthermore, EBV DNA was detected in serum 8 and 52 months prior to the diagnosis of PTLD in two of three patients for whom stored sera were analyzed. Detection of EBV DNA in serum appears to be a useful marker for the early detection of PTLD in solid-organ transplant recipients. Further studies to define the role of such assays in evaluating solid-organ transplant patients at risk for PTLD are warranted.  (+info)

Long-term results of pancreas transplantation under tacrolius immunosuppression. (2/501)

BACKGROUND: The long-term safety and efficacy of tacrolimus in pancreas transplantation has not yet been demonstrated. The observation of prolonged pancreatic graft function under tacrolimus would indicate that any potential islet toxicity is short-lived and clinically insignificant. We report herein the results of pancreas transplantation in patients receiving primary tacrolimus immunosuppression for a minimum of 2 years. METHODS: From July 4, 1994 until April 18, 1996, 60 patients received either simultaneous pancreas-kidney transplant (n=55), pancreas transplant only (n=4), or pancreas after kidney transplantation (n=1). Baseline immunosuppression consisted of tacrolimus and steroids without antilymphocyte induction. Azathioprine was used as a third agent in 51 patients and mycophenolate mofetil in 9. Rejection episodes within the first 6 months occurred in 48 (80%) patients and were treated with high-dose corticosteroids. Antilymphocyte antibody was required in eight (13%) patients with steroid-resistant rejection. RESULTS: With a mean follow-up of 35.1+/-5.9 months (range: 24.3-45.7 months), 6-month and 1-, 2-, and 33-year graft survival is 88%, 82%, 80%, and 80% (pancreas) and 98%, 96%, 93%, and 91% (kidney), respectively. Six-month and 1-, 2-, and 3-year patient survival is 100%, 98%, 98%, and 96.5%. Mean fasting glucose is 91.6+/-13.8 mg/dl, and mean glycosylated hemoglobin is 5.1+/-0.7% (normal range: 4.3-6.1%). Mean tacrolimus dose is 6.5+/-2.6 mg/day and mean prednisone dose 2.0+/-2.9 mg/day at follow-up. Complete steroid withdrawal was possible in 31 (65%) of the 48 patients with functioning pancreases. CONCLUSIONS: These data show for the first time that tacrolimus is a safe and effective long-term primary agent in pancreas transplantation and provides excellent long-term islet function without evidence of toxicity while permitting steroid withdrawal in the majority of patients.  (+info)

Prevention of autoimmune recurrence and rejection by adenovirus-mediated CTLA4Ig gene transfer to the pancreatic graft in BB rat. (3/501)

Type 1 diabetes is the result of a selective destruction of pancreatic islets by autoreactive T-cells. Therefore, in the context of islet or pancreas transplantation, newly transplanted beta-cells are threatened by both recurrent autoimmune and alloimmune responses in recipients with type 1 diabetes. In the present study, using spontaneously diabetic BB rats, we demonstrate that whereas isolated islets are susceptible to autoimmune recurrence and rejection, pancreaticoduodenal grafts are resistant to these biological processes. This resistance is mediated by lymphohematopoietic cells transplanted with the graft, since inactivation of these passenger cells by irradiation uniformly rendered the pancreaticoduodenal grafts susceptible to recurrent autoimmunity. We further studied the impact of local immunomodulation on autoimmune recurrence and rejection by ex vivo adenovirus-mediated CTLA4Ig gene transfer to pancreaticoduodenal grafts. Syngeneic DR-BB pancreaticoduodenal grafts transduced with AdmCTLA4Ig were rescued from recurrent autoimmunity. In fully histoincompatible LEW-->BB transplants, in which rejection and recurrence should be able to act synergistically, AdmCTLA4Ig transduced LEW-pancreaticoduodenal allografts enjoyed markedly prolonged survival in diabetic BB recipients. In situ reverse transcription-polymerase chain reaction revealed that transferred CTLA4Ig gene was strongly expressed in both endocrine and exocrine tissues on day 3. These results indicate the potential utility of local CD28-B7 costimulatory blockade for prevention of alloimmune and autoimmune destruction of pancreatic grafts in type 1 diabetic hosts.  (+info)

Treatment of upper abdominal malignancies with organ cluster procedures. (4/501)

Upper abdominal exenteration for upper abdominal malignancies was carried out in 15 patients with removal of the liver, spleen, pancreas, duodendum, all or part of the stomach, proximal jejunum and ascending and transverse colon. Organ replacement was with the liver, pancreas and duodenum plus, in some cases, a short segment of jejunum. Eleven of the 15 patients survived for more than 4 months; 2 died, after 61/2 and 10 months, of recurrent tumor. Of the 9 patients who are surviving after 61/2 to 14 months, recurrent tumor is suspected in only 1 and proven in none. Four patients with sarcomas and carcinoid tumors (2 each) have had no recurrences. The other 5 survivors had duct cell cancers (3 examples), a cholangiocarcinoma (1 example), and a hepatoma (1 example). The experience so far supports further cautious trials with this drastic cancer operation.  (+info)

Evolution in pancreas transplantation techniques: simultaneous kidney-pancreas transplantation using portal-enteric drainage without antilymphocyte induction. (5/501)

OBJECTIVE: To report initial experience with the combination of a novel technique of portal-enteric pancreas transplantation with newer immunosuppressive strategies that eliminate antilymphocyte induction therapy. BACKGROUND: A new surgical technique of pancreas transplantation has been developed with portal venous delivery of insulin and enteric drainage of the exocrine secretions (portal-enteric). The introduction of potent immunosuppressive agents may allow simultaneous kidney and pancreas transplants (SKPT) to be performed without antilymphocyte induction. METHODS: From September 1996 to November 1998, the authors performed 28 primary SKPTs with portal-enteric drainage and no antilymphocyte induction. All patients received triple immunosuppression with tacrolimus, mycophenolate mofetil, and steroids. The study group had a mean age of 38 years and a mean preoperative duration of diabetes of 25 years. Four patients (14%) had prior kidney transplants. RESULTS: All patients had immediate renal allograft function. Actual patient, kidney, and pancreas graft survival rates were 86%, 82%, and 82%, respectively, after a mean follow-up of 12 months. Four patients died, three as a result of cardiac events unrelated to SKPT. Five kidney and five pancreas grafts were lost, including five deaths with function and three cases of chronic rejection. The mean length of stay and total charges for the initial hospital stay were 12.5 days and $99,517. The mean number of readmissions was 2.9, and 10 patients (36%) had no readmissions. Six patients (21 %) developed acute rejection, with five (18%) receiving antilymphocyte therapy. Seven patients (25%) underwent relaparotomy, including two (7%) for intraabdominal infection. Nine patients (32%) had major infections, including three (11%) with cytomegaloviral infection. Of the 24 surviving patients, 22 (92%) are both dialysis- and insulin-free. CONCLUSION: These preliminary results suggest that SKPT with portal-enteric drainage without antilymphocyte induction can be performed with excellent outcomes.  (+info)

Lipids increase after solitary pancreas transplantation. (6/501)

OBJECTIVE: The aims of this study were to determine 1) changes in lipids after solitary pancreas transplantation (SPTX) in patients with type 1 diabetes and 2) factors that influence those changes. RESEARCH DESIGN AND METHODS: Lipids were evaluated prospectively in 24 patients who underwent SPTX. Three were excluded because of early graft failure. The remaining patients (n = 21; 13 men, 8 women) were studied for changes in lipids over time (pre-SPTX, 0-2, 3-6, 7-12, and > 12 months). Glycohemoglobin, serum creatinine, BMI, and medications were also analyzed for their effects on lipid changes. RESULTS: Cholesterol, HDL, and LDL decreased in the immediate postoperative period (0-2 months), whereas triglycerides (TGs) increased (P < 0.05). At 3-6 months, cholesterol, HDL, and TG were higher than before the SPTX, whereas LDL returned to pre-SPTX levels. After 12 months, HDL and TG remained higher than their pre-SPTX levels (P < 0.05). During the study, systolic and diastolic blood pressure increased, renal function decreased, glyco-hemoglobin improved, and weight was unchanged. Changes in cholesterol/HDL ratio, HDL, and TG correlated with changes in prednisone dose (P < 0.05), and changes in TG correlated with changes in creatinine (P < 0.05). The same pattern of lipids occurred in patients prescribed or not prescribed hypolipidemic agents. CONCLUSIONS: Lipids do not improve within the 1st year after SPTX, despite improved glycemic control and blood pressure control, and renal function is worse. These results are in contrast to those reported for combined kidney-pancreas transplantation, where lipids, blood pressure, and renal function improved immediately after transplant. Further studies are needed to determine whether lipids continue to change with time after SPTX. The impact of these changes after SPTX on overall cardiovascular risk is unknown.  (+info)

Activation and adoptive transfer of Epstein-Barr virus-specific cytotoxic T cells in solid organ transplant patients with posttransplant lymphoproliferative disease. (7/501)

The treatment of Epstein-Barr virus (EBV)-associated lymphoproliferative disease (PTLD) in EBV seronegative solid organ transplant recipients who acquire their EBV infection after engraftment poses a considerable challenge because of underlying immunosuppression that inhibits the virus-specific cytotoxic T cell (CTL) response in vivo. We have developed a protocol for activating autologous EBV-specific CTL lines from these patients and show their potential use for immunotherapy against PTLD in solid organ transplant patients. Peripheral blood mononuclear cells from a panel of solid organ transplant recipients with and without active PTLD were used to assess EBV-specific memory CTL responses. The activation protocol involved cocultivation of peripheral blood mononuclear cells with an autologous lymphoblastoid cell line under conditions that favored expansion of virus-specific CTL and hindered the proliferation of allospecific T cells. These CTL consistently showed (i) strong EBV-specificity, including reactivity through defined epitopes in spite of concurrent immunosuppressive therapy, and (ii) no alloreactivity toward donor alloantigens. More importantly, adoptive transfer of these autologous CTLs into a single patient with active PTLD was coincident with a very significant regression of the PTLD. These results demonstrate that a potent EBV-specific memory response can be expanded from solid organ recipients who have acquired their primary EBV infection under high levels of immunosuppressive therapy and that these T cells may have therapeutic potential against PTLD.  (+info)

Normoglycemia and preserved insulin secretory reserve in diabetic patients 10-18 years after pancreas transplantation. (8/501)

Pancreas transplantation is a controversial form of therapy for type I diabetes. A major obstacle to acceptance of this procedure for many physicians is the lack of demonstrable long-term success. We performed these studies to assess the hypothesis that successful pancreas transplantation is efficacious in normalizing endogenous insulin secretion and glycemia in the long term (1-2 decades). Sixteen patients with a history of diabetic complications who had undergone a transplant 10-18 years earlier involving either a whole or a segment of pancreas were recruited for measurements of fasting plasma glucose, HbA1c, intravenous glucose tolerance, and insulin secretory reserve. All patients were taking immunosuppressive drugs, but none was using insulin or other hypoglycemic agents. All recipients had normal levels of fasting blood glucose, intravenous glucose tolerance, and HbA1c, and 15 of 16 stated that their quality of life had improved after transplantation. They had intact acute insulin responses to intravenous pulses of glucose and to arginine and insulin secretory reserve. Glucose potentiation of arginine-induced insulin secretion, the measure of insulin secretory reserve, correlated significantly (r = 0.095, P < 0.001) with the acute insulin response to intravenous glucose, rendering the latter a much simpler and valid measure of functional beta-cell mass. We conclude that successful pancreas transplants are efficacious for periods as long as 1-2 decades in returning euglycemia to type 1 diabetic patients by restoring endogenous insulin secretion and insulin secretory reserve. Thus, concern about long-term deterioration, as distinct from rejection, should not be a major obstacle when deciding whether to recommend pancreas transplantation.  (+info)

Simultaneous Pancreas/Kidney Transplant Recipients Are Predisposed to Symptomatic CMV-Infection and Concomitant Infectious...Simultaneous Pancreas/Kidney Transplant Recipients Are Predisposed to Symptomatic CMV-Infection and Concomitant Infectious...
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with CMV-infection being the most important viral infection with adverse impact on patient and allograft outcomes. A comparison of CMV-infection between SPKTRs and kidney transplant recipients (KTRs), and the association of CMV-infection with other infectious complications in SPKTRs, however, remains scarcely described.. Here, we studied all primary SPKTRs and primary deceased-donor KTRs (,65 years) at our transplant center between 2008 and 2015 for the development of active CMV-infection. 21 of 62 SPKTRs (33.9%) and 90 of 335 KTRs (26.9%) were diagnosed with CMV viremia. A control group of 41 SPKTRs without CMV viremia was used for comparison.. SPKTRs showed an increased incidence of active CMV-infection compared to KTRs. SPKTRs were more likely to develop CMV-disease, CMV pneumonia, recurrent CMV-infection, higher initial and peak CMV-loads, and more need for intravenous antiviral therapy compared to KTRs ...
https://atcmeetingabstracts.com/abstract/simultaneous-pancreaskidney-transplant-recipients-are-predisposed-to-symptomatic-cmv-infection-and-concomitant-infectious-complications/
There are no differences in pretransplant characteristics of individuals receiving simultaneous pancreas-kidney transplant and...
TY - JOUR. T1 - There are no differences in pretransplant characteristics of individuals receiving simultaneous pancreas-kidney transplant and individuals with type 1 diabetes mellitus receiving living-related kidney transplant. AU - Donigan, L.. AU - Stevens, R. B.. AU - Wrenshall, L.. AU - Larsen, J.. PY - 2004/5. Y1 - 2004/5. N2 - Abstract Simultaneous pancreas-kidney transplantation (SPK) recipients have longer survival compared to type 1 diabetes mellitus (DM1) cadaveric kidney recipients. However, DM1 living-related kidney transplant (KTX-LR) recipients have the same mortality as SPK recipients. It is unknown whether cardiovascular (CVD) risk factors pretransplant are similar between the two groups, SPK and DM1 KTX-LR. We analyzed pretransplant characteristics of SPK recipients (n = 39) and DM1 KTX-LR/living unrelated (LUR) recipients (KTX-LR/LUR, n = 20). In individuals who had multiple transplants, only pretransplant data from the first transplant was used. As all characteristics of ...
https://experts.nebraska.edu/en/publications/there-are-no-differences-in-pretransplant-characteristics-of-indi
Rejection with duodenal rupture after solitary pancreas transplantation: An unusual cause of severe hematuria<...
TY - JOUR. T1 - Rejection with duodenal rupture after solitary pancreas transplantation. T2 - An unusual cause of severe hematuria. AU - Esterl, R. M.. AU - Stratta, R. J.. AU - Taylor, R. J.. AU - Radio, Stanley J. PY - 1995/1/1. Y1 - 1995/1/1. N2 - A common urologic complication after pancreas transplantation with bladder drainage is hematuria. However, hematuria is usually mild and self-limiting and rarely requires open surgical intervention. We report an unusual case of refractory hematuria that began 17 days after solitary pancreas transplantation due to severe rejection. The patient developed severe duodenal segment swelling with mucosal rupture that eventually required operative therapy. This case is illustrative of the diagnosis and management of gross hematuria after pancreas transplantation and demonstrates the limitations of cystoscopic techniques. This unusual complication must be considered in the differential diagnosis of refractory hematuria with pancreas allograft dysfunction and ...
https://nebraska.pure.elsevier.com/en/publications/rejection-with-duodenal-rupture-after-solitary-pancreas-transplan
Simultaneous pancreas-kidney transplantation versus living donor kidney transplantation alone: An outcome-driven choice? |...Simultaneous pancreas-kidney transplantation versus living donor kidney transplantation alone: An outcome-driven choice? |...
The purpose of this review was to investigate this in more detail-in particular the choice between a simultaneous pancreas-kidney transplantation and
https://diabetes.medicinematters.com/type-1-diabetes/metabolic-surgery/simultaneous-pancreas-kidney-transplantation-versus-living-donor/15993762
Pathophysiology of hyperinsulinemia following pancreas transplantation: Altered pulsatile versus basal insulin secretion and...
TY - JOUR. T1 - Pathophysiology of hyperinsulinemia following pancreas transplantation. T2 - Altered pulsatile versus basal insulin secretion and the role of specific transplant anatomy in dogs. AU - Earnhardt, Richard C.. AU - Veldhuis, Johannes D. AU - Cornett, Greg. AU - Hanks, John B.. AU - Andersen, Dana K.. AU - Brunicardi, F. Charles. AU - Thomas, Francis T.. AU - Najarian, John S.. PY - 2002/10. Y1 - 2002/10. N2 - Objective: To evaluate the effect of the anatomical alterations of the pancreas required for transplantation on pulsatile insulin secretion. Summary Background Data: Pancreas transplantation involves anatomical changes that have unknown consequences on glucose homeostasis. Pancreas transplant patients are free of exogenous insulin requirements, yet appear to have endogenous hyperinsulinemia. The effect of surgical alterations on posttransplant insulin release is not completely known, specifically with regards to possible alterations in patterns of pulsatile release. Methods: ...
https://mayoclinic.pure.elsevier.com/en/publications/pathophysiology-of-hyperinsulinemia-following-pancreas-transplant
Effects of pancreas transplantation on postprandial glucose metabolism<...
TY - JOUR. T1 - Effects of pancreas transplantation on postprandial glucose metabolism. AU - Katz, Harold. AU - Homan, Mal. AU - Velosa, Jorge. AU - Robertson, Paul. AU - Rizza, Robert. PY - 1991/10/31. Y1 - 1991/10/31. N2 - Background. Because a pancreas allograft is placed in the pelvis, pancreas transplantation abolishes the normal gradient between portal-vein and peripheral-vein insulin concentrations and causes systemic hyperinsulinemia. Whether pancreas transplantation restores carbohydrate metabolism to normal is not known. Methods. We studied seven patients with insulin-dependent diabetes mellitus after pancreas-kidney transplantation, seven nondiabetic patients after kidney transplantation (to control for immunosuppression), and eight normal subjects. Measurements were made after an overnight fast and after ingestion of a mixed meal. Results. Although plasma glucose concentrations did not differ in the two transplant groups, plasma insulin concentrations were significantly higher in the ...
https://minnesota-staging.pure.elsevier.com/en/publications/effects-of-pancreas-transplantation-on-postprandial-glucose-metab
Surgical complications in solitary pancreas and combined pancreas-kidney transplantations<...
TY - JOUR. T1 - Surgical complications in solitary pancreas and combined pancreas-kidney transplantations. AU - Ozaki, Claire F.. AU - Stratta, Robert J.. AU - Taylor, Rodney J.. AU - Langnas, Alan N.. AU - Bynon, J. Steven. AU - Shaw, Byers W.. PY - 1992/11. Y1 - 1992/11. N2 - The benefits of pancreas transplantation (PT) must be weighed against the morbidity associated with the operative procedure and long-term immunosuppression. Over a 32-month period, we performed 73 PTs including 61 combined pancreas-kidney transplants (PKT) and 12 solitary PTs. In the PKT group, 25 reoperations were performed in 18 patients (29.5%) at a mean of 39±12 days after transplant. In the solitary PT group, 16 reoperations were performed in 8 recipients (66.7%, p=0.03) at a mean of 87±12 days after PT (p,0.01). In the PKT group, pancreas allograft survival was 93.4%. Vascular thrombosis resulted in the loss of two pancreas allografts. In the solitary PT group, pancreas allograft survival was 50% (p,0.001), with 6 ...
https://nebraska.pure.elsevier.com/en/publications/surgical-complications-in-solitary-pancreas-and-combined-pancreas
The History of Pancreas Transplantation: Past, Present and Future | Semantic ScholarThe History of Pancreas Transplantation: Past, Present and Future | Semantic Scholar
During the modern era of immunosuppression, the whole pancreas transplantation technique with enteric diversion became the gold standard for simultaneous Pancreas and kidney transplantation (SPK), with portal drainage of the venous effluent of the pancrea, even for pancreal transplantation after kidney (PAK) or pancreatic transplantation alone (PTA). Abstract The first attempt to cure type 1 diabetes by pancreas transplantation was done at the University of Minnesota, in Minneapolis, on December 17, 1966, followed by a series of whole pancreas transplantation. Due to the lack of potent immunosuppressive drugs, rejections and infections, it was concluded that pancreas was less antigenic than the kidney which was less antigenic than the duodenum. It opened the door to a period, between the mid 70s to mid 80s where only segmental pancreatic grafts were used in the recipient. Numerous techniques for diverting or dealing with the pancreas juice secretion were described, none of them being satisfactory. In
https://www.semanticscholar.org/paper/The-History-of-Pancreas-Transplantation%3A-Past%2C-and-Squifflet-Gruessner/a1f99996705ea5352e087048f5d90d1fb798f1e2
α-Lipoic Acid Protects the Ischemia Reperfusion Injury in Simultaneous Kidney-Pancreas Transplant Patients - ATC Abstractsα-Lipoic Acid Protects the Ischemia Reperfusion Injury in Simultaneous Kidney-Pancreas Transplant Patients - ATC Abstracts
Α-lipoic acid (ALA) is a potent antioxidant. ALA is proposed to mitigate the development of diabetic polyneuropathy by addressing reactive oxygen and nitrogen species. ALA administration is approved for treatment of diabetic sensorimotor polyneuropathy in some countries. Patients that received kidney-pancreas transplantation in order to ameliorate polyneuropathy, may be treated with ALA. Therefore, the aim of the present work was to evaluate the effect of ALA in patients undergoing kidney-pancreatic transplant evaluating functional recovery of graft and biochemical markers of ischemia reperfusion injury (IRI).. The study included 18 kidney-pancreas transplant patients. ALA (600 mg, i.v.) was administered to the deceased donor at the time of ablation and to the recipients during the surgical procedure. Blood samples were obtained at the beginning, the end, 12 h after surgery and every one or two day after transplant for at least 10 days. Cytokines were measured by using a Cytometric Bead Array ...
https://atcmeetingabstracts.com/abstract/lipoic-acid-protects-the-ischemia-reperfusion-injury-in-simultaneous-kidney-pancreas-transplant-patients/?shared=email&msg=fail
Venous thromboembolic complications after kidney and kidney-pancreas transplantation: A multivariate analysis<...Venous thromboembolic complications after kidney and kidney-pancreas transplantation: A multivariate analysis<...
TY - JOUR. T1 - Venous thromboembolic complications after kidney and kidney-pancreas transplantation. T2 - A multivariate analysis. AU - Humar, A.. AU - Johnson, E. M.. AU - Gillingham, K. J.. AU - Sutherland, D. E.. AU - Payne, W. D.. AU - Dunn, D. L.. AU - Wrenshall, L. E.. AU - Najarian, J. S.. AU - Gruessner, R. W.. AU - Matas, A. J.. PY - 1998/1/27. Y1 - 1998/1/27. N2 - Background: We reviewed the incidence of and risk factors for venous thromboembolic complications in our population of kidney (KTx) and simultaneous kidney-pancreas transplant (SPK) recipients. methods: Information was collected retrospectively from a database on 1833 KTx and 276 SPK recipients who underwent transplant surgery between January 1985 and August 1995. Results. The incidence of deep venous thrombosis (DVT) was 6.2%(n = 132), with significantly higher rates after SPK (18.1%) vs. KTx (4.5%) (P,0.001). The number of DVT episodes was highest in the first month; 17.5% occurred during this tine. For KTx recipients, ...
https://experts.umn.edu/en/publications/venous-thromboembolic-complications-after-kidney-and-kidney-pancr
Valganciclovir to Prevent Cytomegalovirus Infection in Kidney and Kidney/Pancreas Transplant Recipients - Full Text View -...Valganciclovir to Prevent Cytomegalovirus Infection in Kidney and Kidney/Pancreas Transplant Recipients - Full Text View -...
Cytomegalovirus in solid organ transplant recipients can result in significant morbidity and mortality due to concurrent immunosuppression. Traditionally intravenous followed by oral ganciclovir has been used to prevent and treat cytomegalovirus infection and disease in transplant recipients. Recently a new oral form of ganciclovir, valganciclovir has been approved by the Food and Drug Administration for the treatment of CMV retinitis in patients with AIDS. Valganciclovir is more bioavailable and requires fewer daily doses and lower pill burden than oral ganciclovir. In addition valganciclovir can attain ganciclovir plasma levels similar to intravenous ganciclovir. This protocol will test the ability of valganciclovir to provide similar drug exposure (area under the curve, AUC) as oral and intravenous ganciclovir at equivalent doses in the setting of kidney and kidney-pancreas transplantation. Patients will receive four different dosing/dosage form schemes. Intravenous ganciclovir at 2.5mg/kg ...
https://clinicaltrials.gov/ct2/show/NCT00034385
THE BENEFITS AND COSTS OF SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION COMPARED WITH DIALYSIS AND KIDNEY-ALONE TRANSPLANTATION...THE BENEFITS AND COSTS OF SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION COMPARED WITH DIALYSIS AND KIDNEY-ALONE TRANSPLANTATION...
R SHINGDE1, V CALISA1, JC CRAIG2, JR CHAPMAN3, AC WEBSTER3, H. PLEASS3, P OCONNEL3L, R ALLEN3, P ROBERTSON3, L YUEN3, K KABLE3, B NANKIVELL3, N ROGERS3, G. WONG2,3. 1Centre for Kidney Research, The Childrens Hospital at Westmead, Westmead; 2Sydney School of Public Health, University of Sydney, Sydney; 3Centre for Transplant and Renal Research, Westmead Hospital, Westmead. Aim: To compare the absolute and relative health gains and costs of simultaneous pancreas kidney (SPK) with deceased donor kidney alone transplantation and dialysis in patients with type 1 diabetes mellitus (DM) and end-stage kidney disease (ESKD).. Background: The long-term costs and health benefits of SPK transplantation, compared to dialysis and deceased donor kidney alone transplant are unclear in this setting.. Methods: Two deterministic Markov models comparing patient survival in patients with Type I DM and ESKD who were either waitlisted on dialysis, received a SPK or deceased donor kidney alone transplantation were ...
https://anzsnasm.com/2500
Advances in pancreas transplantation<...
TY - JOUR. T1 - Advances in pancreas transplantation. AU - Burke, George W.. AU - Ciancio, Gaetano. AU - Sollinger, Hans W.. PY - 2004/5/15. Y1 - 2004/5/15. N2 - Despite early obstacles impacting the success of pancreatic transplantation, the introduction of new procedures and new immunosuppressive therapies during the past 2 decades has improved outcomes for pancreatic transplant recipients. For example, the use of bladder drainage and better human leukocyte antigen matching has helped overcome some of the early obstacles of pancreatic transplantation. In addition, the introduction of tacrolimus in 1994 and mycophenolate mofetil in 1996 has helped lower rates of acute rejection and increase graft survival, with less nephrotoxicity than treatment with cyclosporine. Regimens allowing the tapering of corticosteroids have also helped reduce the rates of acute pancreas rejection. To further improve therapeutic options for patients with type 1 diabetes or end-stage renal disease, pancreatic islet ...
https://miami.pure.elsevier.com/en/publications/advances-in-pancreas-transplantation
Clopidogrel-associated acute migratory arthritis following kidney-pancreas transplantation. - Nuffield Department of Surgical...
Clopidogrel is a potent inhibitor of platelet aggregation and has been used as an alternative, or as an adjunct to aspirin in reducing the risk of thrombosis. A 34-year-old uremic type 1 male diabetic patient who underwent simultaneous kidney-pancreas transplantation was given clopidogrel as he was allergic to aspirin. He developed polyarthralgia one week later, followed in a few days by symmetrical migratory polyarthritis, which resolved completely on withdrawing the drug. The implications to clinical management in a transplant setting are discussed.
https://www.nds.ox.ac.uk/publications/140977
Pancreas allograft rejection: Analysis of concurrent renal allograft biopsies and posttherapy follow-up biopsies<...Pancreas allograft rejection: Analysis of concurrent renal allograft biopsies and posttherapy follow-up biopsies<...
TY - JOUR. T1 - Pancreas allograft rejection. T2 - Analysis of concurrent renal allograft biopsies and posttherapy follow-up biopsies. AU - Troxell, Megan L.. AU - Koslin, David Bradley. AU - Norman, Douglas. AU - Rayhill, Stephen. AU - Mittalhenkle, Anuja. PY - 2010/7/15. Y1 - 2010/7/15. N2 - Background: Pancreas and kidney allograft function is routinely monitored with serum studies (amylase, lipase, and creatinine). Increased levels commonly prompt tissue biopsy, to diagnose cause of graft dysfunction. Historically, pancreas allografts were infrequently biopsied, although serum enzymes and renal rejection may be poor surrogates for pancreas status. Methods: Pancreas allograft biopsies at our center were reviewed and reclassified according to University of Maryland (UMD) and Banff criteria; C4d immunostaining was performed. Findings were correlated with clinical data and renal allograft biopsies. Results: Fifty-six pancreas allograft biopsies from 27 patients were evaluated. UMD and Banff ...
https://ohsu.pure.elsevier.com/en/publications/pancreas-allograft-rejection-analysis-of-concurrent-renal-allogra-2
Long-term survival following simultaneous kidney-pancreas transplantation versus kidney transplantation alone in patients with...Long-term survival following simultaneous kidney-pancreas transplantation versus kidney transplantation alone in patients with...
Am J Kidney Dis. 2003 Feb;41(2):464-70. Comparative Study; Research Support, Non-U.S. Govt; Research Support, U.S. Govt, P.H.S.
https://www.ncbi.nlm.nih.gov/pubmed/12552511
Contrast-enhanced MR angiography for evaluation of vascular complications of the pancreatic transplant<...Contrast-enhanced MR angiography for evaluation of vascular complications of the pancreatic transplant<...
TY - JOUR. T1 - Contrast-enhanced MR angiography for evaluation of vascular complications of the pancreatic transplant. AU - Dobos, Nora. AU - Roberts, David A.. AU - Insko, Erik K.. AU - Siegelman, Evan S.. AU - Naji, Ali. AU - Markmann, James F.. PY - 2005/5. Y1 - 2005/5. N2 - Vascular complications are a common cause of postoperative dysfunction in a pancreatic transplant. Coronal three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiography performed with high spatial and temporal resolution is a safe and effective method of assessing these vascular complications. A study was performed of selected patients who had undergone MR imaging and MR angiography during the past 6 years for evaluation of graft dysfunction following pancreatic transplantation. Thrombosis within peripheral stump vessels involving either the arterial or venous segments was a commonly observed vascular complication. Isolated distal arterial stump thrombi are incidental findings that may not require ...
https://ohsu.pure.elsevier.com/en/publications/contrast-enhanced-mr-angiography-for-evaluation-of-vascular-compl-2
Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan: Case Report<...Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan: Case Report<...
TY - JOUR. T1 - Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan. T2 - Case Report. AU - Sato, Y.. AU - Nakatsuka, H.. AU - Yamamoto, S.. AU - Oya, H.. AU - Kobayashi, T.. AU - Watanabe, T.. AU - Kokai, H.. AU - Kenmochi, T.. AU - Hatakeyama, K.. PY - 2008/10/1. Y1 - 2008/10/1. N2 - In this study, we report a living donor partial pancreas transplantation using intraportal donor-specific leukocyte transfusion (DSLT). The recipient was a 38-year-old woman who had type I diabetes mellitus for 17 years. Hypoglycemia occurred 2 or 3 times per week. Her hemoglobin A1c level was 9.0%, and she required 70 U of insulin almost every day. The donor was her 64-year-old father. The steroid-minimized immunosuppressive protocol included 1.5mg of thymoglobulin administered with a steroid bolus on days 0, 4, and 7 postoperatively. Steroids were never prescribed thereafter. Postoperative maintenance therapy included tacrolimus (FK506) and mycophenolate mofetil. In addition to these ...
https://pure.fujita-hu.ac.jp/en/publications/living-related-pancreas-transplantation-alone-with-enteric-draina
Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan: Case Report<...Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan: Case Report<...
TY - JOUR. T1 - Living Related Pancreas Transplantation Alone With Enteric Drainage in Japan. T2 - Case Report. AU - Sato, Y.. AU - Nakatsuka, H.. AU - Yamamoto, S.. AU - Oya, H.. AU - Kobayashi, T.. AU - Watanabe, T.. AU - Kokai, H.. AU - Kenmochi, T.. AU - Hatakeyama, K.. PY - 2008/10. Y1 - 2008/10. N2 - In this study, we report a living donor partial pancreas transplantation using intraportal donor-specific leukocyte transfusion (DSLT). The recipient was a 38-year-old woman who had type I diabetes mellitus for 17 years. Hypoglycemia occurred 2 or 3 times per week. Her hemoglobin A1c level was 9.0%, and she required 70 U of insulin almost every day. The donor was her 64-year-old father. The steroid-minimized immunosuppressive protocol included 1.5mg of thymoglobulin administered with a steroid bolus on days 0, 4, and 7 postoperatively. Steroids were never prescribed thereafter. Postoperative maintenance therapy included tacrolimus (FK506) and mycophenolate mofetil. In addition to these ...
https://pure.fujita-hu.ac.jp/ja/publications/living-related-pancreas-transplantation-alone-with-enteric-draina
Correlation of genetic markers of rejection with biopsy findings following human pancreas transplant<...Correlation of genetic markers of rejection with biopsy findings following human pancreas transplant<...
TY - JOUR. T1 - Correlation of genetic markers of rejection with biopsy findings following human pancreas transplant. AU - Cashion, Ann. AU - Sabek, Omaima. AU - Driscoll, Carolyn. AU - Gaber, Lillian. AU - Kotb, Malak. AU - Gaber, Osama. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2006/1. Y1 - 2006/1. N2 - Acute rejection after pancreas transplantation remains a significant problem and contributes to immunologic graft loss. No clinical markers of pancreas rejection have been universally accepted. Recent studies have identified several cytotoxic genes as possible markers of acute rejection in renal and islet cell transplant recipients. However, these markers of rejection have not been evaluated in pancreas transplant recipients. This study evaluated the differential expression of granzyme B, perforin, and human leukocyte antigen (HLA)-DRA in peripheral blood between patients with and without biopsy-proven pancreas rejection (n = 7 per group). Gene expression levels ...
https://scholars.houstonmethodist.org/en/publications/correlation-of-genetic-markers-of-rejection-with-biopsy-findings-
Does pancreatic transplantation cure diabetes?Does pancreatic transplantation cure diabetes?
I am a 21 years old male suffering from type 1 diabetes for the last two years. |b|Does pancreatic transplantation cure diabetes|/b|? Are there any post surgery complications of this transplantation?
https://doctor.ndtv.com/faq/does-pancreatic-transplantation-cure-diabetes-13278
Decreased protein binding of mycophenolic acid associated with leukopenia in a pancreas transplant recipient with renal failure...Decreased protein binding of mycophenolic acid associated with leukopenia in a pancreas transplant recipient with renal failure...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
https://www.ncbi.nlm.nih.gov/pubmed/9583876?dopt=Abstract
Use of Ultrasound and Cystoscopically Guided Pancreatic Allograft Biopsies and Transabdominal Renal Allograft Biopsies: Safety...
TY - JOUR. T1 - Use of Ultrasound and Cystoscopically Guided Pancreatic Allograft Biopsies and Transabdominal Renal Allograft Biopsies. T2 - Safety and Efficacy in Kidney-Pancreas Transplant Recipients. AU - Kuhr, Christian S.. AU - Davis, Connie L.. AU - Barr, Darlene. AU - McVicar, John. AU - Perkins, James D.. AU - Bachi, Carlos E.. AU - Alpers, Charles E.. AU - Marsh, Christopher L.. PY - 1995. Y1 - 1995. N2 - The use of allograft biopsies to guide treatment after solid organ transplantation is a valuable tool in the detection and treatment of rejection. Prior development and use of the cystoscopically guided pancreatic allograft biopsy have allowed for more accurate and timely diagnosis of pancreatic allograft dysfunction, possibly contributing to our 1-year pancreas graft, renal allograft and patient survival rates of 87.1%, 88.5% and 96.8%, respectively. We reviewed our experience, examining efficacy and complication rates of pancreas and kidney biopsies in 31 cadaveric pancreas or ...
https://ucdavis.pure.elsevier.com/en/publications/use-of-ultrasound-and-cystoscopically-guided-pancreatic-allograft
Improving monitoring after pancreas transplantation alone: fine-tuning of an old technique. - Surgical Intervention Trials Unit
Graft survival after pancreas transplantation alone (PTA) is significantly poorer than graft survival after simultaneous pancreas kidney (SPK) and is particularly affected by difficulty in monitoring rejection. Exocrine bladder drainage allows assessment of pancreas graft function as urinary amylase (UA). However, standards for UA collection and interpretation are not well defined. In this study, 21 bladder-drained PTA recipients were monitored with daily values for UA and urine creatinine (Creat) concentration from post-transplant 10-mL samples and 24-h collections. Clinical events were documented and correlated to UA measurements. UA values were found to increase post-transplant until day 15, and large interpatient variability was noted (median 12 676 IU/L, range 668-60 369 IU/L). A strong correlation was found total 24-h UA production and spot UA/Creat ratio (r = 0.80, p | 0.001). UA/Creat ratio showed less variation during episodes of impaired renal function; therefore, urinary amylase baseline was
https://www.situ.ox.ac.uk/publications/475170
OPUS 4 | SearchOPUS 4 | Search
Background: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or without impaired renal function. Unfortunately, transplant waiting lists for this indication are increasing because the current organ acceptability criteria are restrictive; morbidity and mortality significantly increase with time on the waitlist. Currently, only pancreas organs from donors younger than 50 years of age and with a body mass index (BMI) less than 30 are allocated for transplantation in the Eurotransplant (ET) area. To address this issue we designed a study to increase the available donor pool for these patients. Methods/Design: This study is a prospective, multicenter (20 German centers), single blinded, non-randomized, two armed trial comparing outcome after SPK, PTA or PAK between organs with the currently allowed donor criteria ...
http://publikationen.ub.uni-frankfurt.de/solrsearch/index/search/searchtype/authorsearch/author/%22Carsten+Dietz%22
OPUS 4 | SearchOPUS 4 | Search
Background: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or without impaired renal function. Unfortunately, transplant waiting lists for this indication are increasing because the current organ acceptability criteria are restrictive; morbidity and mortality significantly increase with time on the waitlist. Currently, only pancreas organs from donors younger than 50 years of age and with a body mass index (BMI) less than 30 are allocated for transplantation in the Eurotransplant (ET) area. To address this issue we designed a study to increase the available donor pool for these patients. Methods/Design: This study is a prospective, multicenter (20 German centers), single blinded, non-randomized, two armed trial comparing outcome after SPK, PTA or PAK between organs with the currently allowed donor criteria ...
http://publikationen.ub.uni-frankfurt.de/solrsearch/index/search/searchtype/authorsearch/author/Michael+Heise/start/0/rows/10/author_facetfq/J%C3%BCrgen+Klempnauer
The effect of antibody induction in simultaneous pancreas kidney (SPK) transplant patients receiving tacrolimus (TAC) and...
Our clinical trials and research studies make a difference in developing new and improved treatment options and preventing threats to public health.
https://secure.emmes.com/emmesweb/publications/1074
Complete reversal of glycogen hepatopathy with pancreas transplantation: Two cases<...
TY - JOUR. T1 - Complete reversal of glycogen hepatopathy with pancreas transplantation. T2 - Two cases. AU - Fridell, Jonathan A.. AU - Saxena, Romil. AU - Chalasani, Naga. AU - Goggins, William C.. AU - Powelson, John A.. AU - Cummings, Oscar. PY - 2007/1. Y1 - 2007/1. N2 - Glycogen hepatopathy is the pathological overloading of hepatocytes with glycogen that is associated with poorly controlled diabetes mellitus. Clinically, it presents with abdominal discomfort, tender hepatomegaly and elevated transaminases. In this report, we describe our experience with two cases of type I diabetes mellitus and glycogen hepatopathy. The patients underwent isolated pancreas transplantation, following which, we have been able to demonstrate complete histological resolution of glycogen hepatopathy associated with control of glucose metabolism.. AB - Glycogen hepatopathy is the pathological overloading of hepatocytes with glycogen that is associated with poorly controlled diabetes mellitus. Clinically, it ...
https://indiana.pure.elsevier.com/en/publications/complete-reversal-of-glycogen-hepatopathy-with-pancreas-transplan
Cardiovascular Risk Factors After Single Pancreas Transplantation - Full Text View - ClinicalTrials.govCardiovascular Risk Factors After Single Pancreas Transplantation - Full Text View - ClinicalTrials.gov
Patients accepted for the waiting list for single pancreas transplantation suffer from severe glucose instability with hyperglycemia due to diabetes type 1, but do not have significant diabetes-related complications. Pancreas transplantation restores normoglycemia in diabetes type 1 patients with unstable control of glycemia. Both hypo- and hyperglycemic events are abolished, and 70-80 % of the patients obtain satisfactory HbA1c levels (HbA1c 5.0-6.0 %) without the need of exogenous insulin. Endothelial dysfunction is considered as an early and potentially reversible stage in the atherosclerotic process. The endothelium is involved in homeostasis, leucocyte adhesion and vasomotor activity. Reduced endothelium-dependent vasodilation is associated with increments in cardiovascular risk factors, and endothelial dysfunction is a predictor for future cardiovascular disease. It has also been hypothesized that endothelial dysfunction may be involved in the impaired glycemic control by reducing the ...
https://clinicaltrials.gov/ct2/show/NCT02066350?recr=Open&intr=%22pancreas+transplantation%22&rank=1
Qualifi cation of patients with diabetes to pancreas transplantation alone | Kałuża | Clinical DiabetologyQualifi cation of patients with diabetes to pancreas transplantation alone | Kałuża | Clinical Diabetology
Pancreas transplantation alone (PTA) is mainly used as a treatment option in poorly controlled type 1 diabetes, although this procedure is more and more often performed in patients with type 2, or other types of diabetes (e.g. after pancreatectomy). Pancreas transplantation alone is aiming at prophylaxy of acute diabetes complications (especially severe hypo- and hyperglycemia), but also at achieving insulin independency and in some cases at prophylaxy of chronic complications. The present paper aims to summarize indications and contraindications for PTA (especially in patients with type 1 diabetes, although type 2 and other types of diabetes are also mentioned), and to shortly describe a process of patients selection and qualifi cation to the procedure ...
https://journals.viamedica.pl/clinical_diabetology/article/view/36064
Simultaneous liver and pancreas transplantation in patients with cystic fibrosis<...
TY - JOUR. T1 - Simultaneous liver and pancreas transplantation in patients with cystic fibrosis. AU - Fridell, J. A.. AU - Vianna, R.. AU - Kwo, P. Y.. AU - Howenstine, M.. AU - Sannuti, A.. AU - Molleston, J. P.. AU - Pescovitz, M. D.. AU - Tector, A. J.. PY - 2005/10/1. Y1 - 2005/10/1. N2 - Background. Improved survival in patients with cystic fibrosis (CF) has led to an increased incidence of extrapulmonary complications of this disease. Of these, cirrhosis and pancreatic insufficiency, including CF-related diabetes (CFRD) and exocrine insufficiency, are significant causes of morbidity and mortality. Liver transplantation is the treatment of choice for cirrhosis in this setting, but the addition of an isolated simultaneous pancreas transplant in patients with CFRD has not been reported. Methods. Two female patients with CF underwent simultaneous pancreas and liver transplantation. Both had pancreatic insufficiency, CFRD, cirrhosis, and preserved renal function. In each case, the liver and ...
https://miami.pure.elsevier.com/en/publications/simultaneous-liver-and-pancreas-transplantation-in-patients-with-
GastroHep News StoryGastroHep News Story
Quality of life is higher in simultaneous pancreas-kidney transplant recipients than in patients receiving renal replacement therapy, finds a study in the latest issue of Clinical Transplantation.. ...
https://www.gastrohep.com/news/news.asp?id=106829
Pancreas-Kidney Transplant Tied to Better Survival Than Kidney Transplant Alone in Type 1 DiabetesPancreas-Kidney Transplant Tied to Better Survival Than Kidney Transplant Alone in Type 1 Diabetes
Compared with kidney transplantation alone, simultaneous pancreas-kidney (SPK) transplantation was associated with an almost twofold lower 10-year mortality among type 1 diabetics, in a retrospective study.. The study included all 2,796 patients with type 1 diabetes in the Netherlands who started renal replacement therapy or received a first kidney transplant between 1986 and 2016. As reported in Diabetes Care, of the 996 who received new kidneys, 42% received a deceased-donor kidney; 16%, a living-donor kidney; and 42%, an SPK transplant. Crude survival was highest in SPK recipients and lowest in recipients of a deceased-donor kidney. Median survival time was 7.3 years for deceased-donor kidney recipients; 10.5 years for living-donor kidney recipients; and 16.5 years for SPK recipients.. @media (min-width:500px){#social{padding:0 0 15px 67px}#link{display:none!important}#facebook{padding:0 29px 0 24px}}@media screen and ...
https://www.emedinexus.com/post/15901/
Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja.<...
TY - JOUR. T1 - Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja.. AU - Kalmár Nagy, Károly. AU - Baumann, János. AU - Szakály, Péter. AU - Gyori Molnár, Iván. AU - Wittmann, I.. AU - Lodge, Peter. AU - Horváth Ors, Péter. PY - 2004/6/13. Y1 - 2004/6/13. N2 - INTRODUCTION: Simultaneous pancreas kidney (SPK) transplantation is the only routinely used therapeutic option which can provide insulin independence, euglycemia and good renal replacement. AIMS: Analysis of the five years experience of the first Hungarian SPK transplants. MATERIAL: From 29 October 1998. through 31 December 2003. 32 SPK transplants were performed from 53 type 1 diabetes mellitus patients with ESRD on the waiting list. Enteric drainage was performed in all transplanted patients in 20 combined with systemic venous drainage, whereas in 12 patients portal venous drainage was used. In 18 patients only maintenance ...
https://hungary.pure.elsevier.com/en/publications/simultaneous-pancreas-kidney-transplantation-an-alternative-optio
Impaired cyclosporine absorption after delayed native pancreatectomy in canine whole pancreas transplantation<...Impaired cyclosporine absorption after delayed native pancreatectomy in canine whole pancreas transplantation<...
TY - JOUR. T1 - Impaired cyclosporine absorption after delayed native pancreatectomy in canine whole pancreas transplantation. AU - Wilson, T. G.. AU - Hawthorne, W. J.. AU - Williamson, P.. AU - Allen, R. D M. AU - Deane, S. A.. AU - Grierson, J. M.. AU - Stewart, G. J.. AU - Little, J. M.. PY - 1989. Y1 - 1989. UR - http://www.scopus.com/inward/record.url?scp=0024806133&partnerID=8YFLogxK. M3 - Article. C2 - 2815286. AN - SCOPUS:0024806133. VL - 21. SP - 3799. EP - 3800. JO - Transplantation Proceedings. JF - Transplantation Proceedings. SN - 0041-1345. IS - 5. ER - ...
https://researchers.mq.edu.au/en/publications/impaired-cyclosporine-absorption-after-delayed-native-pancreatect
View supporters for Albert Humphreys Kidney/Pancreas Transplant Fund - Help Hope LiveView supporters for Albert Humphreys Kidney/Pancreas Transplant Fund - Help Hope Live
View supporter messages for Albert Humphreys Kidney/Pancreas Transplant Fund on Help Hope Live. Your tax-deductible donation can make a difference today.
https://helphopelive.org/campaign/1812/activities/n
Fundraiser by Julie McKervey : Kidney/pancreas transplantFundraiser by Julie McKervey : Kidney/pancreas transplant
Many of you know that Matt was diagnosed with Type 1 Diabetes at just 6 years old. What you … Julie McKervey needs your support for Kidney/pancreas transplant
https://www.gofundme.com/f/kidneypancreas-transplant
Basiliximab vs Thymoglobulin: Who wins in Induction Immunosuppressive Therapy after Kidney Transplantation?Basiliximab vs Thymoglobulin: Who wins in Induction Immunosuppressive Therapy after Kidney Transplantation?
Bazerbachi, F., Selzner, M., Boehnert, M.U., Marquez, M.A., Norgate, A., McGilvray, I.D., Schiff, J. and Cattral, M.S., 2011. Thymoglobulin versus basiliximab induction therapy for simultaneous kidney-pancreas transplantation: impact on rejection, graft function, and long-term outcome. Transplantation, 92(9), pp.1039-1043.. Chen, G., Gu, J., Qiu, J., Wang, C., Fei, J., Deng, S., Li, J., Huang, G., Fu, Q. and Chen, L., 2013. Efficacy and safety of thymoglobulin and basiliximab in kidney transplant patients at high risk for acute rejection and delayed graft function. Exp Clin Transplant, 11(4), pp.310-314.. Deeks, E.D. and Keating, G.M., 2009. Rabbit Antithymocyte Globulin (Thymoglobulin®). Drugs, 69(11), pp.1483-1512.. Favi, E., Gargiulo, A., Spagnoletti, G., Salerno, M.P., Silvestrini, N., Valente, I. and Citterio, F., 2010, May. Induction with basiliximab plus thymoglobulin is effective and safe in old-for-old renal transplantation: six-month results of a prospective clinical study. In ...
https://solmeglas.com/basiliximab-vs-thymoglobulin-who-wins-in-induction-immunosuppressive-therapy-after-kidney-transplantation/
Agnesian HealthCare - Pancreas Transplantation
Pancreas transplantation is a type of surgery in which you receive a healthy donor pancreas. It is a choice for some people with type 1 diabetes.
http://healthlibrary.agnesian.com/Library/DiseasesConditions/Adult/Liver/134,172
Pancreas Transplantation
Pancreas transplantation is a type of surgery in which you receive a healthy donor pancreas. It is a choice for some people with type 1 diabetes.
http://wellness.gwinnettmedicalcenter.org/Library/DiseasesConditions/Adult/Liver/134,172
Send a Message to the Kidney & Pancreas Transplant Team | Cedars-SinaiSend a Message to the Kidney & Pancreas Transplant Team | Cedars-Sinai
Have a question about kidney and pancreas transplantation? Need a second opinion or physician referral? Send a message to the kidney and pancreas transplant team at Cedars-Sinai.
https://www.cedars-sinai.org/programs/transplant-center/programs/kidney-pancreas/send-a-message.html
Plus itPlus it
Insulin resistance is a characteristic feature in recipients of a pancreas transplant, but the relative contribution of the liver and peripheral tissues to this abnormality within a spanning range of insulin concentrations is unknown. To assess the impact of insulin action on glucose metabolism after pancreas transplantation, a euglycemic-hyperinsulinemic clamp with sequential insulin infusions (5, 40, and 200 mU m−2·min−1 for 120 min each), combined with isotopic determinations of the rates of hepatic glucose production and extrahepatic glucose uptake, indirect calorimetry, and measurements of glycogen synthase and hexokinase activities in vastus lateralis muscle, were performed in six pancreas-kidney transplant recipients (Px group) and compared with those performed in six nondiabetic kidney transplant recipients with similar immunosuppression (Kx group) and six nondiabetic control subjects. The overall effects of insulin on whole-body glucose metabolism, determined as the glucose ...
http://diabetes.diabetesjournals.org/content/45/9/1267
Pancreatic Transplant - An Introduction to Islet Cell Transplant
Diabetes patients with high levels of glucose and low insulin in their blood often take up a pancreatic transplant once they are cleared for the procedure, as this is a surgical method of providing them a new lease of life.
http://www.zipheal.com/islet-cell-tranplant/pancreatic-transplant/785
The impact of prolonged cold ischemia on delayed graft function (DGF) in pancreas transplantation.The impact of prolonged cold ischemia on delayed graft function (DGF) in pancreas transplantation.
inproceedings{116331, author = {Troisi, Roberto and MEESTER, D and DE RYCK, F and Cuvelier, Claude and HESSE, UJ}, booktitle = {TRANSPLANTATION}, issn = {0041-1337}, language = {eng}, number = {9}, pages = {S652-S652}, title = {The impact of prolonged cold ischemia on delayed graft function (DGF) in pancreas transplantation.}, volume = {67}, year = {1999 ...
https://biblio.ugent.be/publication/116331
Unexpected deterioration of graft function after combined kidney and pancreas transplantation - Zurich Open Repository and...Unexpected deterioration of graft function after combined kidney and pancreas transplantation - Zurich Open Repository and...
Schleich, A; Fehr, T; Gaspert, A; Wuthrich, R P; Mohebbi, N (2013). Unexpected deterioration of graft function after combined kidney and pancreas transplantation. Clinical Kidney Journal, 6(2):228-230. ...
http://www.zora.uzh.ch/id/eprint/90089/
Pancreas Transplantation - Immunology; Allergic Disorders - MSD Manual Professional EditionPancreas Transplantation - Immunology; Allergic Disorders - MSD Manual Professional Edition
Pancreas Transplantation - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.
https://www.msdmanuals.com/en-sg/professional/immunology-allergic-disorders/transplantation/pancreas-transplantation
Montefiore Einstein Center for Transplantation - Heart, Liver, Kidney, Pancreatic Transplantation Teams - New York CityMontefiore Einstein Center for Transplantation - Heart, Liver, Kidney, Pancreatic Transplantation Teams - New York City
With more than 40 years of leadership in transplantation, Montefiore is committed to the care of patients with conditions affecting the heart, liver, kidney and pancreas.
http://www.montefiore.org/blank.cfm?id=1188&iirf_redirect=1&displayheader=No&action=emailfriend&originalAction=None
Why the Risk of Developing Neuroarthropathy Is Higher After Simultaneous Kidney and Pancreatic Transplantation Compared to...Why the Risk of Developing Neuroarthropathy Is Higher After Simultaneous Kidney and Pancreatic Transplantation Compared to...
ABSTRACT:Charcots neuroarthropathy is a destructive complication of the joint, which is often found in patients living with diabetes. Despite the fact that its description was published almost 100 years ago, its pathophysiology, diagnosis, and treatment remain areas that need to be updated. Its prevalence is low in patients living with diabetes, but this increases in particular situations such as peripheral neuropathy, as well as after simultaneous kidney-pancreas transplantation (SPKT) in patients living with type 1 diabetes. We suggest that the development of neuroarthropathy after SPK in not only due to glucocorticoid therapy, as described, but also to the rapid passage into euglycemia. The reduced prevalence of neuroarthropathy after only kidney transplantation compared to SPK seems to validate our hypothesis.
https://www.annalsoftransplantation.com/abstract/index/idArt/928449
Deep wound infections in simultaneous pancreas: Kidney transplant recipients on peritoneal dialysis<...
TY - JOUR. T1 - Deep wound infections in simultaneous pancreas. T2 - Kidney transplant recipients on peritoneal dialysis. AU - Douzdjian, V.. AU - Abecassis, M.. PY - 1995/4. Y1 - 1995/4. KW - Abscess. KW - Pancreas transplant. KW - Peritoneal dialysis. UR - http://www.scopus.com/inward/record.url?scp=0028932695&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0028932695&partnerID=8YFLogxK. U2 - 10.1093/ndt/10.4.533. DO - 10.1093/ndt/10.4.533. M3 - Article. C2 - 7623997. AN - SCOPUS:0028932695. VL - 10. SP - 533. EP - 536. JO - Nephrology Dialysis Transplantation. JF - Nephrology Dialysis Transplantation. SN - 0931-0509. IS - 4. ER - ...
https://www.scholars.northwestern.edu/en/publications/deep-wound-infections-in-simultaneous-pancreas-kidney-transplant-
Meet our Transplant Physicians - Hackensack UMCMeet our Transplant Physicians - Hackensack UMC
Dr. Goldstein joins Hackensack University Medical Center from the Miami Transplant Institute, where he served as chief of the Division of Transplantation, and the University of Miami Miller School of Medicine, where he served as associate professor of Clinical Surgery. His surgical, academic and executive experience also includes service as associate professor of Surgery and director of Renal and Pancreatic Transplantation at Mount Sinai Medical Center, and as medical director of the New York Organ Donor Network. Board-certified in general surgery, Dr. Goldstein is a fellow of the American College of Surgeons, and a member of the American Society for Transplant Surgeons, American Society for Transplantation, and the Association of Academic Surgeons. His clinical expertise includes: kidney and pancreas transplantation surgery, donor management, renal machine perfusion, general surgery, laparoscopy, hepatobiliary surgery, acute care surgery and vascular access surgery. Dr. Goldstein served as a ...
https://www.hackensackumc.org/services/organ-transplants/our-transplant-surgeons/
Pancreatic cancer treatment with segmental pancreas resection: Costs for treatment #51925 in Germany | BookingHealthPancreatic cancer treatment with segmental pancreas resection: Costs for treatment #51925 in Germany | BookingHealth
Pancreatic cancer treatment with segmental pancreas resection (costs for program #51925) ✔ Alfried Krupp Hospital in Essen-Ruettenscheid ✔ Department of General and Abdominal Surgery ✔ BookingHealth.com
https://bookinghealth.com/alfried-krupp-krankenhaus-r-ttenscheid/treatment-programs/51925-pancreatic-cancer-treatment-with-segmental-pancreas-resection.html
Most recent papers with the keyword Liver, Renal & Pancreas transplantation | Read by QxMDMost recent papers with the keyword Liver, Renal & Pancreas transplantation | Read by QxMD
BACKGROUND: Although over the past decade the management of invasive fungal infection has improved, considerable controversy persists regarding antifungal prophylaxis in solid organ transplant recipients. AIMS: To identify the key clinical knowledge and make by consensus the high level recommendations required for antifungal prophylaxis in solid organ transplant recipients. METHODS: Spanish prospective questionnaire, which measures consensus through the Delphi technique, was conducted anonymously and by e-mail with 30 national multidisciplinary experts, specialists in invasive fungal infections from six national scientific societies, including intensivists, anesthetists, microbiologists, pharmacologists and specialists in infectious diseases that responded to 12 questions prepared by the coordination group, after an exhaustive review of the literature in the last few years ...
https://www.readbyqxmd.com/keyword/48013
Technical Note: Facilitating Laparoscopic Liver Biopsy by the Use of a Single-Handed Disposable Core Biopsy NeedleTechnical Note: Facilitating Laparoscopic Liver Biopsy by the Use of a Single-Handed Disposable Core Biopsy Needle
HPB Surgery is a peer-reviewed, Open Access journal that offers ready access to important developments in the field of HPB surgery and associated disciplines. We aim to publish fresh experimental and clinical work across the spectrum of HPB disease, while concentrating on those conditions for which surgical treatment - not necessarily an actual operation - is a common option. Thus diabetes mellitus and hepatitis, for example, might belong more appropriately elsewhere, though not if the paper should concern pancreatic transplantation or virally-induced hepatoma.
https://www.hindawi.com/journals/hpb/2013/462498/ref/
Choledochal Cyst Associated With Polycystic Kidney Disease: Report of a CaseCholedochal Cyst Associated With Polycystic Kidney Disease: Report of a Case
HPB Surgery is a peer-reviewed, Open Access journal that offers ready access to important developments in the field of HPB surgery and associated disciplines. We aim to publish fresh experimental and clinical work across the spectrum of HPB disease, while concentrating on those conditions for which surgical treatment - not necessarily an actual operation - is a common option. Thus diabetes mellitus and hepatitis, for example, might belong more appropriately elsewhere, though not if the paper should concern pancreatic transplantation or virally-induced hepatoma.
https://www.hindawi.com/journals/hpb/1999/038936/abs/
Clinical transplantation surgery and experimental immunology - Institute of Clinical Medicine
The research group is also working on clinical issues related kidney, liver and pancreas transplantation. Surgical technique, surgical complications, patient- and graft survival, graft function and preservation and donor criteria are important areas of the research Projects.. The main goals in experimental immunology is to map and identify new therapeutic targets. We use biochemical, cellular biological og functional immunological methods to investigate intracellular signal transduction pathways in mainly T cells. Our main goals in clinical transplantation surgery are to improve the prognosis and patient survival in kidney, liver and pancreas recipients and to optimize graft function. We also aim to improve the availability of donor organs by using extended criteria for donor selection and increase the quality of the organs by new preservation Methods.. ...
https://www.med.uio.no/klinmed/english/research/groups/clinical-transplantation-surgery-experimental-immunology/index.html
Clinical and epidemiological differences and risk factors for death among solid organ transplant recipients with Gram-positive...Clinical and epidemiological differences and risk factors for death among solid organ transplant recipients with Gram-positive...
Describe clinical and epidemiological differences and risk factors for death among Bloodstream Infections (BSI) caused by Gram Negative (GN) and Gram Positive (GP) bacteria in the setting of solid organ transplantation. We performed a retrospective analysis of medical records, which were evaluated patients undergoing solid organ transplantation with BSI in the period from January 2000 to January 31, 2006 at Hospital São Paulo and Hospital do Rim e Hipertensão (Universidade Federal de São Paulo, Brazil). It was also performed the analysis of risk factors for death. 195 patients were included in this study with a mean age of 43.3 (± 0.90) years, 114 (58.5 %) were male and, 81 (41.5 %) were female. 168 (86.2 %) were kidney transplants, 16 (8.2 %) kidney-pancreas, 5 (2.6 %) heart, 5 (2.6 %) liver and 1 (0.5 %) liver-kidney. The mean hospital stay was 34.2 (± 62.7) days. GN accounted for 147 (75.4 %) of the BSI episodes, whereas 48 (24.6 %) were caused by GP. In the group with BSI by GN the most common
https://safetyinhealth.biomedcentral.com/articles/10.1186/s40886-015-0007-0
Find a Doctor | UTMBHealth.comFind a Doctor | UTMBHealth.com
Dr. Muhammad A. Mujtaba graduated from the Allama Iqbal Medical College, Punjab University Lahore, Pakistan in 1999-2000. He did his Internal Medicine Residency from the Columbia University New York at Harlem Hospital Center. He completed his Nephrology and Hypertension fellowship from Columbia University in 2008. He completed his Transplant Fellowship from Indiana University School of Medicine in 2009, and served as Transplant Nephrology faculty at the same place till December 2014. Dr. Mujtaba was instrumental in the initiation and maintenance of transplant outreach, paired donor exchange, and desensitization program for Indiana University. Dr. Mujtaba joined as the Medical Director for Kidney and Pancreas Transplants at University of Texas Medical Branch (UTMB-Texas Transplant Center) in January 2015. Dr. Mujtaba has extensive clinical and research experience in kidney and pancreas transplantation including high risk transplant, immunomodulation/desensitization protocols, early steroid ...
https://doctors.utmbhealth.com/ProviderSearch/Default/?id=019930
Meet the Team | VASBIMeet the Team | VASBI
Presdient: Mr James Gilbert, Consultant Transplant & Vascular Access Surgeon, Churchill Hospital, Old Rd, Headington, Oxford OX3 7LE Tel: 0300 304 7777 Email: [email protected]. James is currently working as a Consultant Transplant and Vascular Access Surgeon at the Oxford University Hospitals NHS Foundation Trust. He is a specialist in kidney and and pancreas transplantation and vascular access surgery and has particular interest and expertise in complex and re-do and salvage access surgery and access in patients with central vein pathology.. James currently leads the dialysis access and pancreas transplant programmes. He inserted Europes first HeRO graft in 2013 and currently has the biggest European experience of HeRO graft usage in central vein stenosis. He has also developed a vascular access programme for patients with intestinal failure. James is an educationalist and has a Masters in Education. He is involved with undergraduate and postgraduate training and has been responsible for the ...
https://www.vasbi.org.uk/meet-the-team/
Canine liver transplantation under Nva2-cyclosporine versus cyclosporine. | PMID 3513388 | Transplantation March 01, 1986 |...
Evolution of liver transplantation. Hepatology (1982) 19.54 FK 506 for liver, kidney, and pancreas transplantation. Lancet (1989) 13.70 A flexible procedure for multiple cadaveric organ procurement. Surg Gynecol Obstet (1984) 10.33 Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance. Hepatology (1993) 8.76 Orthotopic liver transplantation in ninety-three patients. Surg Gynecol Obstet (1976) 8.11 The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet (1980) 7.40 The use of heterologous antilymphoid agents in canine renal and liver homotransplantation and in human renal homotransplantation. Surg Gynecol Obstet (1967) 7.24 Fifteen years of clinical liver transplantation. Gastroenterology (1979) 7.19 Venous bypass in clinical liver transplantation. Ann Surg (1984) 7.04 Liver transplantation with use of cyclosporin a and prednisone. N Engl J Med (1981) 6.95 The many faces of multivisceral transplantation. Surg Gynecol ...
https://pubrank.carbocation.com/pmid/3513388
Abdominal Transplantation: Pancreas (incl. Kidney/Pancreas) - The Clinical AdvisorAbdominal Transplantation: Pancreas (incl. Kidney/Pancreas) - The Clinical Advisor
Physician assistants and nurse practitioners use Clinical Advisor for updated medical guidance to diagnose and treat common medical conditions in daily practice.
http://www.clinicaladvisor.com/critical-care-medicine/abdominal-transplantation-pancreas-incl-kidneypancreas/article/584865/
Organ Transplantation CenterOrgan Transplantation Center
Medical Park Organ Transplantation Center enjoys a reputation for its investments, specialization and success stories not only within Turkey but also around the world.. Medical Park is on par with worlds foremost centers operating in the fields of organ failure and organ transplantation, in terms of advanced technology and specialization. 800 organ transplantations are being performed per year at Medical Park Hospitals Group.. As part of its mission to save more people lives, Medical Park started performing organ transplantations in 2008 and performed 68 organ transplantations within its first year. Medical Park has performed 2.331 kidney, liver and pancreas transplantations to date, 512 being in 2009, 544 in 2010, 564 in 2011 and 643 in 2012. The success rates it has achieved in these operations are equivalent to those observed in the U.S.. In 2012, the total number of kidney transplantations performed at Turkish institutions authorized by Ministry of Health was 2903. During the same year, the ...
https://medicalparkinternational.com/en-us/areas-of-excellence/Pages/organ-transplantation-center.aspx
Tomasz Kozlowski, MD - transplantTomasz Kozlowski, MD - transplant
Tomasz Kozlowski, MD, was born in Poland and graduated from the six-year program at the Medical University of Warsaw in 1985. From 1985- 1989, he completed the general and vascular surgery training program at Medical University of Warsaw, where he became a member of the faculty and the busy kidney/pancreas transplant team. He continued training in organ transplantation in Stockholm, Sweden, at the Karolinska Institute, one of the most prestigious European centers. Then he joined Transplantation Biology Research Center at Harvard Medical School to continue studies on transplantation tolerance, biology of xenograft rejection, bone marrow transplantation and engraftment, biology of antibody mediated rejection, and coagulopathy in humoral rejection.. After fulfilling requirements of the American Board of Surgery and completing his general surgery residency at Stony Brook University on Long Island, NY, he augmented his clinical transplant experience as a fellow at the Division of Transplantation at ...
http://www.med.unc.edu/surgery/transplant/faculty/TKozlowski
Patient Care - Chicago MedicinePatient Care - Chicago Medicine
The Division of Nephrology at UI Health treats patients with conditions and diseases of the kidney, including end-stage renal disease (ESRD), kidney transplantation, acute kidney failure, kidney stones, and immunological kidney diseases at the University of Illnois Outpatient Care Center. Our kidney transplant outcomes are among the best in Chicago. The Division of Nephrology has grown out of a long history of excellence in the field of kidney treatment and research.. In the early 1950s, UI Health nephrologists refined and developed the percutaneous kidney biopsy as a clinical tool. UI Health was the first institution in Illinois to perform a living-donor kidney/pancreas transplant and the first in the world to perform a robotic donor nephrectomy (kidney removal) for a living-donor transplant.. #pageTitle{border-bottom-width:5px !important} ...
http://chicago.medicine.uic.edu/departments/academic-departments/medicine/nephrology/patient-care/
Dr. Sarah Hallberg on triglycerides, LDL and HDL cholesterol on a ketogenic diet - Hyderabad Literary Festival
I began eating a HFLC ketogenic diet on August 23rd 2018 where my total cholesterol was 156 months earlier. The reason for going on keto was not so much to lose weight but inflammation where Ive had a history of diabetes with a kidney/pancreas transplant x 2. A few months after going strict ketovore, eating 50-70% of my TDEE ub fat I had another lipid test on December 13th revealing a total of 770 where LDL was 658! Im 52 years old and in pretty good shape with a BMI of 23. I work out with resistance training 5-6 days per week. Ive not heard anyone yet who has had their numbers go this high after going on a HFLC diet?. ...
https://hyderabadliteraryfestival.com/dr-sarah-hallberg-on-triglycerides-ldl-and-hdl-cholesterol-on-a-ketogenic-diet/
UFDC - Timeline - UF Health Science Archives Photograph Collections
1995 Southeasts first umbilical cord blood transplant on an infant and adult performed; states first kidney/pancreas transplant occurs; first gene therapy treatment for brain cancer is done. HIV saliva test, developed by UF veterinarian, is released to the marketplace in several foreign countries; 13-week-old Gary Weems of Pensacola, Fla., has a heart transplant performed at Shands, becoming first infant to undergo a heart transplant in Florida ...
http://ufdc.uflib.ufl.edu/hsca/timeline
Plus itPlus it
Assessing the risk-to-benefit ratio for solitary islet transplantation is a challenge and has to be individualized. The risks associated with the procedure have been documented (3,4,16), but assessing the indications of problematic hypoglycemia and glycemic lability has been subjective. Some patients cope well with recurrent hypoglycemia or erratic glucose levels that would be disabling for others. Some perspective on the severity of the problem compared with the general diabetes clinic population would be helpful for the physician and patient, and standardization of the assessment of islet transplant patients across various sites would be beneficial. There is a similar need for the assessment of subjects for solitary pancreas transplant.. The frequency of severe hypoglycemia in the Diabetes Control and Complications Trial was 0.61 episodes per patient per year (6). Allen et al. (17) reported that one-third of patients with type 1 diabetes, mainly younger and with a duration of diabetes of 4-6 ...
http://diabetes.diabetesjournals.org/content/53/4/955
Lee S Cummings, MD | Saint Lukes Health SystemLee S Cummings, MD | Saint Lukes Health System
Dr. Cummings attended medical school at St. Georges University School of Medicine. He then went on to complete his general surgery residency at Maimonides Medical Center in New York City. His training culminated at Georgetown University where he completed a fellowship in Abdominal Organ Transplant and Hepatobiliary Surgery. He specializes in liver, intestine, multivisceral, kidney and pancreatic transplant. He is also trained in the management of benign and malignant diseases of the bile duct, liver and pancreas.
http://saintlukeskc.org/doctor/lee-s-cummings-md
C-Peptide Response to Glucose, 7 Specimens - Quest Diagnostics Nichols Institute of ValenciaC-Peptide Response to Glucose, 7 Specimens - Quest Diagnostics Nichols Institute of Valencia
C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplant) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). It is also sometimes measured as an additional means (more resistant to hemolysis than is insulin itself) for evaluating glucose tolerance tests ...
http://www.specialtylabs.com/tests/details.asp?id=15847
C-Peptide Response to Glucose, 8 Specimens - Quest Diagnostics Nichols Institute of ValenciaC-Peptide Response to Glucose, 8 Specimens - Quest Diagnostics Nichols Institute of Valencia
C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplant) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). It is also sometimes measured as an additional means (more resistant to hemolysis than is insulin itself) for evaluating glucose tolerance tests ...
http://www.specialtylabs.com/tests/details.asp?id=15848
Pancreas Transplant Fundraiser - Emme Jo
While you can never be truly prepared, mentally and monetarily, for a life altering event like an organ transplant we werent expecting this time to come so soon.. Instead of a total pancreatectomy she will be getting a total pancreatectomy and islet auto transplant, or TP-IAT. University of Minnesota Health has a great article called FIVE THINGS YOU SHOULD KNOW ABOUT (TP-IAT) SURGERY. The short version in laymen terms is they remove the pancreas, pull out the islet cells that product insulin and infuse them into the liver. The liver then hosts the islets. If they take, this essentially tricks the liver into producing insulin like the pancreas. Her chances of being Type 1 diabetic are only about 20%.. The process to get this procedure consists of an initial 4 day consultation. Her case would then be presented to the board for acceptance. After acceptance there would be a couple week inpatient stay after the procedure. Due to the rigorous follow up schedule Emily and Liz will be required to live ...
http://www.emmejo.com/pancreas-transplant-fundraiser/
Montefiore Einstein Center for Transplantation - Resources - Brochures - New YorkMontefiore Einstein Center for Transplantation - Resources - Brochures - New York
Links to brochures providing additional information on liver disease and transplantation, as well as for kidney and pancreas transplantation.
http://www.montefiore.org/transplant-resources-brochures
Florida Doctor - FLDR Spring 2017
8 f l o r i d a d o c t o r O ver the course of the last five decades, University of Florida Health Shands Trans- plant Center faculty and staff have performed more than 8,000 organ transplants. ey provide lifesaving care for adult patients receiving heart, liver, lung, kidney and pancreas transplants. e center also provides care for pediatric patients receiving heart, lung, kidney and pancreas transplants. UF Health Shands Hospital is fully committed to organ transplantation. UF was the first center in the state to provide most of these lifesaving procedures. e intent is to build on this foundation and enhance the care of the patients in the region, said Bruce Mast, MD, a professor and chief of plastic and reconstructive surgery at the UF College of Medicine. He is also interim chair for the UF Depart- ment of Surgery. UF Healths multidisciplinary team includes surgeons, physician specialists, nurses, financial coordinators, donor coordinators, administrative support staff, social workers, ...
http://issues.floridadoctormag.com/i/822762-fldr-spring-2017/7?m4=
First-of-Its-Kind Procedure Combines Scalp, Skull, Kidney and Pancreas Transplant
The experience may open the way to further procedures combining vascularized composite allotransplantation (VCA) with organ transplants, in patients who have already accepted the need for lifelong immunosuppressive therapy. Hopefully, this case and others like it will help to widen the narrow indications for this fascinating new field of reconstructive surgery, write Dr. Jesse Creed Selber of The University of Texas M.D. Anderson Cancer Center and colleagues ...
http://donatelife-organdonation.blogspot.com/2016/05/first-of-its-kind-procedure-combines.html
Academic Overview | Nephrology and Hypertension | UC Cincinnati College of Medicine - ..WB1PRD01W-Med.uc.eduAcademic Overview | Nephrology and Hypertension | UC Cincinnati College of Medicine - ..WB1PRD01W-Med.uc.edu
The UC Division of Nephrology, Kidney CARE Program is fully engaged in educating medical students, residents and fellows in all aspects of renal disease, physiology, kidney and pancreas transplantation and hypertension.
https://med.uc.edu/intmed/divisions/nephrology-and-hypertension/overview
Nephron Power: Renal Fellow Network: Pancreas transplant pearlsNephron Power: Renal Fellow Network: Pancreas transplant pearls
Here is a concept map of early causes of AKI- what others and we have seen in NY. As you can see, tubular cause most likely but other comp ...
http://www.nephronpower.com/2010/10/renal-fellow-network-pancreas.html
Complications of diabetes | Islet cell transplantationComplications of diabetes | Islet cell transplantation
A lack of donors and high cost are the major limiting factors. Each successful islet transplant currently needs five donor pancreases, though some groups have had success with a single donor pancreas. There are a very small number of donors in relation to very large numbers of people with diabetes. Worldwide, it is thought there are only enough organs to transplant 1 in 200 (0.5%) people with type 1 diabetes.. Your immune system is programmed to destroy foreign cells. At present immunosuppressive drugs are needed to prevent rejection of these transplantated cells by the body. These drugs are associated with side effects which may be harmful. The long term effects of these drugs are not yet known. It is thought that taking immunosuppressive drugs increases the risk of cancer as well.. ...
http://diabetesuffolk.com/Complications/Islet%20cell%20transplantation.htm
UNOS Monthly Waiting List Report as of 12/31/13UNOS Monthly Waiting List Report as of 12/31/13
UNITED NETWORK FOR ORGAN SHARING. Monthly Waiting List Snapshot Report. December 31, 2013. This report provides frequency counts for certain demographic and logistic factors (blood type, gender, age, ethnicity, Region) for patients awaiting transplantation on the OPTN kidney, liver, pancreas, kidney-pancreas, intestine, heart, heart-lung, and lung organ-specific waiting lists.. The counts in this report are based on a recent snapshot of the OPTN Waiting List, i.e., the waiting list as it existed around midnight on the date specified. The data contained in the OPTN system are not conveyed via paper forms, but are entered electronically by the OPTN members who list a particular potential recipient. OPTN members have direct responsibility for maintaining and monitoring all data from the time a patient is listed until they are removed from the list. Values of demographic variables are obtained from Transplant Candidate Registration forms when missing on the waiting list snapshot.. Note that some ...
http://www.trioweb.org/news/item/unos-monthly-waiting-list-report-as-of-12-31-13.html
ModelDB: Parallel odor processing by mitral and middle tufted cells in the OB (Cavarretta et al 2016, 2018)ModelDB: Parallel odor processing by mitral and middle tufted cells in the OB (Cavarretta et al 2016, 2018)
from spikesreader import SpikesReader from geodist import glomdist def cell2spk(sr, cells): n = 0. for x in cells: n += len(sr.retrieve(x)) return n/len(cells) def mc2spk(sr, glomid): return cell2spk(sr, range(glomid * 5, (glomid + 1) * 5)) def mt2spk(sr, glomid): return cell2spk(sr, range(glomid * 10 + 635, (glomid + 1) * 10 + 635)) fo = open(../out-dist-0-0.txt, w) for g in [78,77,110,105,126,47,29,86,30,24,62,1,125,70,20,15,0,121,115,92,65,55,51,48,120]: sr = SpikesReader(out-0-0-g%d-li.spk2 % g) sr37 = SpikesReader(out-0-0-g%d-li.spk2 % 37) fo.write(%g %g %g\n%(glomdist(g, 37), mc2spk(sr, g) / (0. + mc2spk(sr37, 37)), mt2spk(sr, g) / (0. + mt2spk(sr37, 37)))) fo.close ...
https://senselab.med.yale.edu/modeldb/ShowModel?model=240116&file=%2Fmodeldb-bulb3d%2Fvis%2Fspk2gd.py
Purpose of The PancreasPurpose of The Pancreas
Purpose of The Pancreas What is the pancreas? Most people know what organs like the heart, lungs and kidneys do, but fewer are familiar with the pancreas and what role it serves. The pancreas is multipurpose because it serves more than one function in the body.
http://www.seenamagowitzfoundation.org/what-is-the-pancreas/
Cancer pancreas body, Pancreatita Acuta Si Cancer de Pancreas | Pancreas | Abdomen
Mama ta a murit din cauza unei pancreas infectat. Timp de răspuns: 53 ms. Less stress on my pancreas, still battle the infection.
http://punctultau.ro/cancer-pancreas-body-552267.php
NewYork-Presbyterian Queens - The Pancreas: Anatomy and Functions
The pancreas is an elongated, tapered organ located across the back of the abdomen, behind the stomach. The right side of the organ, called the head, is the widest part of the organ and lies in the curve of the duodenum, the first section of the small intestine. The tapered left side extends slightly upward, called the body of the pancreas, and ends near the spleen, called the tail.. The pancreas is made up of two types of glands:. ...
http://www.nyhq.org/diw/content.asp?pageid=P00682
Pathology of the Pancreas - Pathology of the Pancreas Alyssa Krasinskas MD krasinskasam@upmc.edu January 6 2003 Normal...Pathology of the Pancreas - Pathology of the Pancreas Alyssa Krasinskas MD [email protected] January 6 2003 Normal...
View Notes - Pathology of the Pancreas from STEP 1 at Montgomery College. Pathology of the Pancreas Alyssa Krasinskas, MD [email protected] January 6, 2003 Normal Peripancreatic fat Pancreatic
https://www.coursehero.com/file/6651821/Pathology-of-the-Pancreas/
function of the pancreas - Graph Diagram
Function Of The Pancreas Diagram - Chart - diagrams and charts with labels. This diagram depicts Function Of The Pancreas and explains the details of Function Of The Pancreas. ...
http://graphdiagram.com/function-of-the-pancreas/
RIDDELL POWER SPK+ OL/DL
Replacing the Riddell Power SPK OL/DL, the SPK+ OL/DL features Riddell RipKord Technology�, the STAC shoulder system, swivel fronts, biothane STAC straps and belts, a flat pad design, the air management liner system, removable/adjustable bodies, stainless
http://qa.riddell.com/shop/on-field-equipment/shoulder-pads/riddell-power-spk-ol-dl.html
Q: Im using your PANCREAS CLEANSE AND REGIMEN and this is my second week....Q: Im using your PANCREAS CLEANSE AND REGIMEN and this is my second week....
A: Glad to hear all is going well with this cleanse! Great news and thanks for sharing! After the PANCREAS CLEANSE AND REGIMEN I would recommend a daily regimen of: PANCREAS...
https://www.dherbs.com/question/im-using-your-pancreas-cleanse-and-regimen-and-this-is-my-second-week-whats/
What Are The Meanings and Significance Of These Terms Related To Diabetes: Beta Cells, Islets, Glucagon, and Amylin? -...What Are The Meanings and Significance Of These Terms Related To Diabetes: Beta Cells, Islets, Glucagon, and Amylin? -...
The terms can get pretty technical, but there is a simple way to look on it. The way I think of it is that, first of all, the pancreas is a pretty big organ. In a supermarket, the pancreas is a sweetbread, thats the sweetbread, the pancreas of the cow, but that is a pancreas.
http://abcnews.go.com/Health/DiabetesOverview/story?id=3843612
Anomalies of pancreas, congenital - RightDiagnosis.comAnomalies of pancreas, congenital - RightDiagnosis.com
Anomalies of pancreas, congenital information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
http://www.rightdiagnosis.com/medical/anomalies_of_pancreas_congenital.htm
Gentaur Molecular :Biochai \ cDNA Human Adult Normal Tissue Pancreas \ C1234188Gentaur Molecular :Biochai \ cDNA Human Adult Normal Tissue Pancreas \ C1234188
Gentaur molecular products has all kinds of products like :search , Biochai \ cDNA _ Human Adult Normal Tissue Pancreas \ C1234188 for more molecular products just contact us
http://www.antibody-antibodies.com/product_det.php?id=321718&supplier=search&name=cDNA%20_%20Human%20Adult%20Normal%20Tissue%20%20Pancreas
Pancreas
We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok ...
https://www.eneabrivio.com/catalog/pathology/pancreas/
PancreasPancreas
Your account has been temporarily locked Your account has been temporarily locked due to incorrect sign in attempts and will be automatically unlocked in 30 mins. For immediate assistance, contact Customer Service: 800-638-3030 (within USA), 301-223-2300 (international) [email protected] ...
https://journals.lww.com/pancreasjournal/pages/userregister.aspx?ContextUrl=%2Fpancreasjournal%2Fsecure%2Fpages%2Fpurchase.aspx%3Fan%3D00006676-202008000-00006
Time Flies. | The Girl with the Portable PancreasTime Flies. | The Girl with the Portable Pancreas
Hello. So its been over a year since Ive last posted. And I think thats okay. That just means I have a lot of important things going on in my life and nothing exciting to share ;) I thought Id not only give the site a make over but also provide some kind of update…
https://portablepancreasgirl.com/2018/03/07/time-flies/
સ્વાદુપિંડ - વિકિપીડિયાસ્વાદુપિંડ - વિકિપીડિયા
સ્વાદુપિંડ (પેન્ક્રિયાસ; Pancreas) એ શરીરમાં જઠર અને નાના આંતરડાની વચ્ચે આવેલું એક અંગ છે, જેમાં પાચક રસો (સોમાટોસ્ટેટિન, પેન્ક્રિયાટિક પોલિપેપ્ટાઇડ બને છે. આ પાચક રસોનો સ્ત્રાવ થવાને કારણે નાના આંતરડામાં વિટામીનોનું શોષણ થવાથી તેમ જ ખોરાકમાંના કાર્બોહાઇડ્રેટ, પ્રોટિન તથા ચરબીનું પાચન થવાને કારણે પાચનક્રિયા સરળ બને છે. સ્વાદુપિંડમાં ઈન્સ્યુલિન અને ગ્લુકાગોનનો સ્ત્રાવ થાય છે, જેના ...
https://gu.wikipedia.org/wiki/%E0%AA%B8%E0%AB%8D%E0%AA%B5%E0%AA%BE%E0%AA%A6%E0%AB%81%E0%AA%AA%E0%AA%BF%E0%AA%82%E0%AA%A1
pancreas - சொல்வனம் | இதழ் 246 | 9 மே 2021pancreas - சொல்வனம் | இதழ் 246 | 9 மே 2021
எழுத்தாளர்கள் எந்தப் படைப்பை சொல்வனத்துக்கு அனுப்பினாலும் அது வோர்ட் ஃபார்மட் கோப்பாக இருக்க வேண்டும். (யூனிகோட், ஃபானெடிக் அச்சு எழுத்தாகவும் இருக்க வேண்டும்.) இதை இணைப்பாக அனுப்புங்கள். இதர வடிவுகளில் அனுப்ப வேண்டாம். (உதா: பிடிஎஃப், மின்னஞ்சலின் பகுதியாக என்று அனுப்பாதீர்கள் ...
https://solvanam.com/pancreas/
Something Funky. | The Girl with the Portable PancreasSomething Funky. | The Girl with the Portable Pancreas
I realized today that Im in some kind of funk. I dont know if its a touch of the winter blues. Im not sure if its from the sinus crud that has been plaguing me lately. I dont know if I have a bit of burnout. But I do know that I havent really been…
https://portablepancreasgirl.com/2014/01/04/something-funky/
Pancreas transplantationPancreas transplantation
The majority of pancreas transplantations (> 90%) are simultaneous pancreas-kidney transplantations. Complications immediately ... This is the least performed method of pancreas transplantation and requires that only the pancreas of a donor is given to the ... There are four main types of pancreas transplantation: Pancreas transplant alone, for the patient with type 1 diabetes who ... Advancement in immunosuppression has improved quality of life after transplantation. In most cases, pancreas transplantation is ...
https://en.wikipedia.org/wiki/Pancreas_transplantation
Richard C. LilleheiRichard C. Lillehei
History of Pancreas Transplantation". Transplantation of the Pancreas. Springer. pp. 45-46. ISBN 0-387-00589-7. Han, Duck Jong ... Every two years an award is given to the most outstanding clinician in the field of pancreas transplantation. "History of ... Thomas, Beje (16 May 2018). "Kidney-Pancreas Transplantation: Overview, Periprocedural Care, Technique". Medscape. "The C. ... "Pancreas Transplantation". Gut and Liver. 4 (4): 450-465. doi:10.5009/gnl.2010.4.4.450. ISSN 1976-2283. PMC 3021600. PMID ...
https://en.wikipedia.org/wiki/Richard_C._Lillehei
DiabetesDiabetes
"Pancreas Transplantation". American Diabetes Association. Archived from the original on 13 April 2014. Retrieved 9 April 2014. ... Insulin is released into the blood by beta cells (β-cells), found in the islets of Langerhans in the pancreas, in response to ... A pancreas transplant is occasionally considered for people with type 1 diabetes who have severe complications of their disease ... Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the ...
https://en.wikipedia.org/wiki/Diabetes
C. Walton LilleheiC. Walton Lillehei
History of Pancreas Transplantation". Transplantation of the Pancreas. Springer. pp. 45-46. ISBN 978-0-387-00589-8. History of ... having participated in the world's first successful transplant of a pancreas in 1966 and the first known human transplant of ... who formed half of the quartet which pioneered heart transplantation (the others being Richard Lower and Adrian Kantrowitz). In ...
https://en.wikipedia.org/wiki/C._Walton_Lillehei
University of Minnesota Medical SchoolUniversity of Minnesota Medical School
Casanova, Daniel (May 2017). "Pancreas transplantation: 50 years of experience". Cirugía Española (English Edition). 95 (5): ... Ballen, Karen K.; Gluckman, Eliane; Broxmeyer, Hal E. (2013-07-25). "Umbilical cord blood transplantation: the first 25 years ... Muratore, Sydne; Freeman, Martin; Beilman, Greg (20 February 2015). "Total Pancreatectomy and Islet Auto Transplantation for ... services and blood and marrow and organ transplantation. The Duluth program began in late 1972. It is now a branch campus of ...
https://en.wikipedia.org/wiki/University_of_Minnesota_Medical_School
Edmonton protocolEdmonton protocol
Pancreas transplantation for treatment of diabetes mellitus. World J Surg. 2001 Apr;25(4):487-96. [7] Shapiro AMJ, Ricordi C, ... However, only 1,562 pancreases were recovered from donors in 2011. Also, many donated pancreases are not suitable for ... Islet isolation and transplantation was pioneered by Paul Lacy throughout the 1960s. He and Walter Ballinger together were able ... Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N ...
https://en.wikipedia.org/wiki/Edmonton_protocol
Patrick Soon-ShiongPatrick Soon-Shiong
... liver and pancreas. During the modern era of immunosuppression, the whole pancreas transplantation technique with enteric ... Whole pancreas transplantation began as a part of multi-organ transplants, in the mid-to-late 1960s, at the University of ... The first attempt to cure type 1 diabetes by pancreas transplantation was done at the University of Minnesota, in Minneapolis, ... See Squifflet, J.P.; Gruessner, R.W.; Sutherland, D.E. (2008). "The History of Pancreas Transplantation: Past, Present and ...
https://en.wikipedia.org/wiki/Patrick_Soon-Shiong
Northwestern Memorial HospitalNorthwestern Memorial Hospital
"Pancreas and Islet Cell Transplantation Specialists and Care Centers". Northwestern Medicine. Archived from the original on ... In 1996, surgeons from Northwestern Memorial Hospital became the first in Illinois to perform an islet cell transplantation. On ... organ transplantation, and weight loss. The Simpson Querrey Biomedical Research Center opened in 2019 and is expected to ...
https://en.wikipedia.org/wiki/Northwestern_Memorial_Hospital
Mark A. HardyMark A. Hardy
Transplantation of the Endocrine Pancreas in Diabetes Mellitus. R. van Schilfgaarde, M.A. Hardy (eds.). Elsevier Science ... His most recent focus has been on cellular transplantation with emphasis on islet transplantation. Hardy is Principal ... In addition to his work in transplantation, in the earlier part of his career he made several contributions to the development ... 1968-1971 Hardy is an editor of Transplantation and has published more than 300 articles on subjects varying from surgical ...
https://en.wikipedia.org/wiki/Mark_A._Hardy
Immunosuppressive drugImmunosuppressive drug
Pancreas-Kidney Transplantation: Drugs, a brief history of immunosuppressive drugs. Accessed on 21 August 2005. WSAVA 2001 - ... The drug is used primarily in liver and kidney transplantations, although in some clinics it is used in heart, lung, and heart/ ... They are used in the prophylaxis of the acute organ rejection after bilateral kidney transplantation, both being similarly ... Non-melanoma skin cancer (NMSC) after kidney transplantation is common and can result in significant morbidity and mortality. ...
https://en.wikipedia.org/wiki/Immunosuppressive_drug
Cystic fibrosisCystic fibrosis
October 2005). "Simultaneous liver and pancreas transplantation in patients with cystic fibrosis". Transplantation Proceedings ... Damage to the pancreas can lead to loss of the islet cells, leading to a type of diabetes unique to those with the disease. ... The pancreas contains the islets of Langerhans, which are responsible for making insulin, a hormone that helps regulate blood ... Lung transplantation may be an option if lung function continues to worsen. Pancreatic enzyme replacement and fat-soluble ...
https://en.wikipedia.org/wiki/Cystic_fibrosis
BK virusBK virus
"Low incidence of BK virus nephropathy after simultaneous kidney pancreas transplantation". Transplantation. 82 (3): 382-8. doi: ... Typically, this is in the setting of kidney transplantation or multi-organ transplantation. Presentation in these ... isolated from urine after renal transplantation". Lancet. 1 (7712): 1253-7. doi:10.1016/s0140-6736(71)91776-4. PMID 4104714. ... of surveillance and rapid reduction in immunosuppression to control BK virus-related graft injury in kidney transplantation". ...
https://en.wikipedia.org/wiki/BK_virus
Ioanel SinescuIoanel Sinescu
... kidney transplantation at the University of Cape Town; and in 2005, pancreas transplantation at the University of Minnesota ... Since 1997, he has headed the Centre for Urological Surgery, Dialysis and Kidney Transplantation at the Fundeni Clinical ... Dialysis and Kidney Transplantation site; accessed November 6, 2009 (in Romanian) "Ionel Sinescu, noul rector al Universității ... and kidney transplantation in Tel Aviv; in 1991-1992, urologic oncology, reconstructive surgery, endourology and kidney ...
https://en.wikipedia.org/wiki/Ioanel_Sinescu
Islet cell transplantationIslet cell transplantation
Islet transplantation is the transplantation of isolated islets from a donor pancreas into another person. It is an ... Health Quality Ontario (2015). "Pancreas Islet Transplantation for Patients With Type 1 Diabetes Mellitus: A Clinical Evidence ... "Strategic opportunities in clinical islet transplantation". Transplantation. 79 (10): 1304-7. doi:10.1097/01.TP. ... The goal of islet transplantation is to infuse enough islets to control the blood glucose level removing the need for insulin ...
https://en.wikipedia.org/wiki/Islet_cell_transplantation
Allan KirkAllan Kirk
Kirk is an American transplant surgeon and physician, specializing in kidney and pancreas transplantation. He is ... He was senior investigator and chief of the Transplantation Branch for the NIDDK from 2001 to 2007. During that time, he also ... He served as editor-in-chief for the American Journal of Transplantation from 2010 through 2020, and is now Editor Emeritus. ... Kirk has made significant contributions to transplantation over the past 20 years, specifically in the areas of novel immune ...
https://en.wikipedia.org/wiki/Allan_Kirk
Histidine-tryptophan-ketoglutarateHistidine-tryptophan-ketoglutarate
Follow-up experience using histidine-tryptophan-ketoglutarate solution in clinical pancreas transplantation Transplant Proc. ... HTK solution is intended for perfusion and flushing of donor liver, kidney, heart, lung and pancreas prior to removal from the ... 4. Pokorny H., et al.: Histidine-tryptophan-ketoglutarate solution for organ preservation in human liver transplantation - a ... low-potassium preservation solution used for organ transplantation. The solution was initially developed by Hans-Jürgen ...
https://en.wikipedia.org/wiki/Histidine-tryptophan-ketoglutarate
Insulin (medication)Insulin (medication)
Transplantation of an entire pancreas (as an individual organ) is difficult and relatively uncommon. It is often performed in ... Another improvement would be a transplantation of the pancreas or beta cell to avoid periodic insulin administration. This ... "Islet transplantation for brittle type 1 diabetes: the UIC protocol". American Journal of Transplantation. 8 (6): 1250-61. doi: ... A long-acting insulin is used to approximate the basal secretion of insulin by the pancreas, which varies in the course of the ...
https://en.wikipedia.org/wiki/Insulin_(medication)
Johannes Hoffmann (vascular surgeon)Johannes Hoffmann (vascular surgeon)
In 2002 Hoffmann performed his first independent transplantations of kidney and pancreas. In 2003 he became specialist for ... Hoffmannscientifi work is focussed on ischemia Reperfusion Injury, Sepsis, Transplantation, vascular access surgery, bypass ...
https://en.wikipedia.org/wiki/Johannes_Hoffmann_(vascular_surgeon)
Ernesto Pompeo MolmentiErnesto Pompeo Molmenti
Intestinal and Multivisceral Transplantation, Kidney and Pancreas Transplantation (translated into Spanish), Thyroidectomy: ... Liver Transplantation, Pediatric Transplantation, Radiology, Surgery, and Transplantation. He also authored 8 books: Atlas of ... Molmenti, Ernesto P. (2015). Kidney and pancreas transplantation. Donald and Barbara Zucker School of Medicine at Hofstra/ ... Pancreas Transplantation. Jaypee Brothers,Medical Publishers Pvt. Limited. ISBN 978-93-5152-339-0. Herman, Wendy. "LibGuides: ...
https://en.wikipedia.org/wiki/Ernesto_Pompeo_Molmenti
Gaetano CiancioGaetano Ciancio
Together with George Burke, Ciancio has made contributions to the field of pancreas transplantations both regarding management ... "Arterial reconstruction with donor iliac vessels during pancreas transplantation: an intraoperative approach to arterial injury ... sirolimus in renal transplantation. Ii. Survival, function, and protocol compliance at 1 year". Transplantation. Ovid ... "The Use of Campath-1H as Induction Therapy in Renal Transplantation: Preliminary Results". Transplantation. Ovid Technologies ( ...
https://en.wikipedia.org/wiki/Gaetano_Ciancio
Organ donationOrgan donation
Common transplantations include kidneys, heart, liver, pancreas, intestines, lungs, bones, bone marrow, skin, and corneas. Some ... Australian Organ Donor Register Organ transplantation in Israel Organ transplantation in China MOHAN Foundation Sri Lanka Eye ... Wicks, Mona Newsome (April 25, 2000). "Brain Death and Transplantation: The Japanese". Medscape Transplantation. Retrieved ... When a recipient for a kidney or pancreas has no direct antibodies to the donor HLA the match is said to be a 0 ABDR mismatch ...
https://en.wikipedia.org/wiki/Organ_donation
Nadey HakimNadey Hakim
In 1995, he performed London's first pancreas transplantation at St Mary's Hospital and began the first pancreas transplant ... he performed London's first pancreas transplantation. He was part of the team that performed the first kidney transplantation ... He is also a writer, musician and sculptor, known for kidney and pancreas transplantations, and being part of the surgical team ... Co-edited with Franco Favretti, Bruno Dilemans and Gianni Segato Whole Organ Pancreas Transplantation. In Nagy A. Habib and ...
https://en.wikipedia.org/wiki/Nadey_Hakim
Rudolf PichlmayrRudolf Pichlmayr
During his time at the MHH he was involved in 4,278 transplantations of liver, kidney and pancreas. Together with his wife Ina ... He is considered a pioneer in liver transplantation. The introduction of the term "transplantation medicine" goes back to ... Just one year later he was head of the Department of Special Surgery and Transplantation. In 1973, Pichlmayr finally became ... In 1988, Pichlmayr performed the world's first so-called split-liver transplantation, in which the donor liver was divided and ...
https://en.wikipedia.org/wiki/Rudolf_Pichlmayr
Donald DafoeDonald Dafoe
He previously worked at Cedars-Sinai Medical Center, where he was Director of the Pancreas Transplantation, Kidney and Pancreas ... "Pancreas Transplant Director Donald Dafoe Joins Cedars-Sinai". Cedars-Sinai Medical Center press release via Newswise.com. May ... and Transplantation Science. Ex-husband to vascular surgeon Dr. Rhoda Dafoe and Sahara Dafoe, he is a father of six, and is the ... where he is chief of transplantation surgery. ...
https://en.wikipedia.org/wiki/Donald_Dafoe
J. Michael MillisJ. Michael Millis
Living Donor Organ Transplantation (2007) "Pancreas and Islet Allotransplantation". In: Shackelford's Seventh Edition Surgery ... "Transplantation for Biliary Atresia". In: Transplantation of the Liver (1996) "Liver Transplantation". In: Maingot's Abdominal ... Impact of graft type on outcome in pediatric liver transplantation: a report from Studies of Pediatric Liver Transplantation ( ... Liver Transplantation 18 (6), 716-726. (2012) J Huang, JM Millis, Y Mao, MA Millis, X Sang, S Zhong: A pilot programme of organ ...
https://en.wikipedia.org/wiki/J._Michael_Millis
Human betaherpesvirus 5Human betaherpesvirus 5
It may be used for the prophylaxis of cytomegalovirus disease associated with transplantation of kidney, lung, liver, pancreas ... Lohr, J.M; Oldstone, M.B.A (1990). "Detection of cytomegalovirus nucleic acid sequences in pancreas in type 2 diabetes". The ... a study by the European group for blood and marrow transplantation". Clin Infect Dis. 59 (4): 473-81. doi:10.1093/cid/ciu364. ... Transplantation. 100 (10): e74-e80. doi:10.1097/TP.0000000000001418. PMC 5030152. PMID 27495775. Erice, A. (1999). "Resistance ...
https://en.wikipedia.org/wiki/Human_betaherpesvirus_5
Rainer GruessnerRainer Gruessner
This is the most eminent award in the field of pancreas transplantation and transplantation of diabetic patients. Gruessner has ... Gruessner has edited three standard textbooks including Transplantation of the Pancreas and Living Donor Organ Transplantation ... Gruessner was a member of the team that performed the world's first split pancreas transplant and the world's first pancreas ... Lillehei Award by the International Pancreas and Islet Transplantation Society in Lyon, France. ...
https://en.wikipedia.org/wiki/Rainer_Gruessner
Royal Infirmary of EdinburghRoyal Infirmary of Edinburgh
... pancreas and pancreatic islet cell transplantation and one of two sites for kidney transplantation in Scotland. In 2012, the ... "In Coming Days" The Edinburgh Royal Infirmary Souvenir Brochure 1942 "History of Kidney Transplantation". www.edren.org. ... Scotland's first combined kidney and pancreas transplant 2008 - Scotland's first live donor liver transplant by Murat Akyol and ... Ernest Hidalgo 2011 - Scotland's first pancreatic islet cell transplantation 2012 - Scotland's first transcatheter aortic valve ...
https://en.wikipedia.org/wiki/Royal_Infirmary_of_Edinburgh
R. Paul RobertsonR. Paul Robertson
... in metabolic studies of type 1 diabetic patients who have successfully received pancreas and pancreatic islet transplantation ( ...
https://en.wikipedia.org/wiki/R._Paul_Robertson
Carl-Gustav GrothCarl-Gustav Groth
He was the first surgeon in Sweden to perform pancreas transplantation (1974), liver transplantation (1984), and islet cell ... transplantation (1996). He published over 600 articles and a 1984 book, Pancreas Transplantation. He became a professor of ... He pioneered transplantation of various organs, including the liver, pancreas, kidney and bone marrow, as well as ... where he performed the first pancreas, liver and islet cell transplantation surgeries in Sweden. Groth was born in 1933 in ...
https://en.wikipedia.org/wiki/Carl-Gustav_Groth
Genomic imprintingGenomic imprinting
Nucleus transplantation experiments in mouse zygotes in the early 1980s confirmed that normal development requires the ... Scharfmann R (2007). Development of the Pancreas and Neonatal Diabetes. Karger Publishers. pp. 113-. ISBN 978-3-8055-8385-5. ...
https://en.wikipedia.org/wiki/Genomic_imprinting
List of Puerto Rican scientists and inventorsList of Puerto Rican scientists and inventors
Diego R. Solís is the founder and director of the "Centro de Cirugias de Higado y Pancreas" (Liver and Pancreas Surgery Center ... Organ transplantation Iván González Cancel is a cardiovascular and thoracic surgeon who is credited with the realization of the ... He is a professor of surgery at the University of Puerto Rico and program director of transplantation of organs of the " ... On March 9, 2007, Solís performed, in the "Hospital Auxilio Mutuo" (Mutual Aid Hospital), the first simultaneous pancreas and ...
https://en.wikipedia.org/wiki/List_of_Puerto_Rican_scientists_and_inventors
VoriconazoleVoriconazole
Omrani AS, Almaghrabi RS (December 2017). "Complications of hematopoietic stem transplantation: Fungal infections". Hematology/ ... and pancreas damage; trouble with vision; and adverse effects in skin including damage due to phototoxicity, squamous cell skin ... World Journal of Transplantation. 11 (9): 356-371. doi:10.5500/wjt.v11.i9.356. PMC 8465512. PMID 34631468. "Vfend loses its ...
https://en.wikipedia.org/wiki/Voriconazole
Biliary sludgeBiliary sludge
... solid organ transplantation, and gastric surgery. In many of these conditions, it is thought that the impairment in the ... biliary tract and pancreas). ...
https://en.wikipedia.org/wiki/Biliary_sludge
Organ donation in IndiaOrgan donation in India
"Organ Transplantation in India". Retrieved 29 April 2020. "The Andhra Pradesh Transplantation of Human Organs Act, 1995" (PDF ... Vital organs such as the heart, pancreas, liver, kidneys, and lungs can be transplanted from the donor to a person whose organs ... Organ transplantation is a medical procedure where one organ removed from one person and placed in the body of recipient. ... The Andhra Pradesh Transplantation of Human Organs Act, 1995, was enacted by the government shortly after the central act. The ...
https://en.wikipedia.org/wiki/Organ_donation_in_India
Human Transplantation (Wales) Act 2013Human Transplantation (Wales) Act 2013
... pancreas and kidneys and corneas) to be available for transplant, a person must consent to their use on an 'opt-in' basis. That ... Organ transplantation in the United Kingdom, 2013 in British politics, Transplantation medicine). ... The Human Transplantation (Wales) Act 2013 (anaw 5) (Welsh: Deddf Trawsblannu Dynol (Cymru) 2013) is an act of the National ... The Human Transplantation (Wales) Bill was laid before the National Assembly for Wales on 4 December 2012, by Lesley Griffiths ...
https://en.wikipedia.org/wiki/Human_Transplantation_(Wales)_Act_2013
AutotransfusionistAutotransfusionist
... pancreas, and small bowel transplants Hip replacement Knee replacement Hysterectomy Myomectomy Endovascular aneurysm repair ... Abdominal aortic aneurysm Liver transplantation/Liver resection Jehovah Witness with patient approval and expected large blood ...
https://en.wikipedia.org/wiki/Autotransfusionist
Pearson syndromePearson syndrome
Pancreas. Pearson syndrome causes the exocrine pancreas to not function properly because of scarring and atrophy. Individuals ... Single Dose Clinical Study to Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-BM-BLD (Autologous cd34+ ... With the pancreas not functioning properly, this leads to high levels of fats in the liver. PMPS can also lead to diabetes and ... Pearson marrow pancreas syndrome (PMPS) is a condition that presents itself with severe reticulocyto-penic anemia. ...
https://en.wikipedia.org/wiki/Pearson_syndrome
History of medicineHistory of medicine
Transplantations of other organs, such as heart, liver and pancreas, were also introduced during the later 20th century. The ... In 1954 Joseph Murray, J. Hartwell Harrison and others accomplished the first kidney transplantation. ...
https://en.wikipedia.org/wiki/History_of_medicine
CholestasisCholestasis
If gallstones prevent bile flowing from the pancreas to the small intestine, it can lead to gallstone pancreatitis. Physical ... Due to disease progression, 40% of patients eventually require liver transplantation, which has survival rates (91% at 1 year, ... This drug stimulates biliary bicarbonate secretion, improves survival without having to resort to a liver transplantation, and ... Kamath BM, Schwarz KB, Hadzić N (January 2010). "Alagille syndrome and liver transplantation". Journal of Pediatric ...
https://en.wikipedia.org/wiki/Cholestasis
SpleenSpleen
Below this it is in contact with the tail of the pancreas. The renal surface is directed medialward and downward. It is ... vein and its tributaries Spleen Laparoscopic view of human spleen Asplenia with cardiovascular anomalies Spleen transplantation ...
https://en.wikipedia.org/wiki/Spleen
Panangipalli VenugopalPanangipalli Venugopal
He pioneered the stem cell implantation procedure in pancreas for the treatment of Type II Diabetes. On the prolificacy of ... where he performed the first heart transplantation in India on 3 August 1994 and, later, for the first time in Asia, the ... by the deployment of autologous stem cell implantation for repairing the myocardium as an alternative to transplantation, which ...
https://en.wikipedia.org/wiki/Panangipalli_Venugopal
Organ donation after medical assistance in dyingOrgan donation after medical assistance in dying
Organs regularly transplanted include lungs, heart, cornea, pancreas, and kidneys. Modes of donation are an altruistic living ... January 2021). "Lung donation after medical assistance in dying at home". American Journal of Transplantation. 21 (1): 415-418 ... Transplantation. 97 (3): 258-264. doi:10.1097/01.TP.0000437178.48174.db. PMID 24492420. S2CID 13906287. Downar J, Shemie SD, ... American Journal of Transplantation. 22 (3): 999-1000. doi:10.1111/ajt.16879. PMID 34706144. S2CID 240072648. Radbruch L, Leget ...
https://en.wikipedia.org/wiki/Organ_donation_after_medical_assistance_in_dying
Kanan Yusif-zadaKanan Yusif-zada
... and that December worked as visitor physician at the Department of General Surgery and Kidney and Pancreas Transplantation at ... Kidney Transplantation. Kanan Yusif-zada gained his first medical experience in 1991-1996 as a senior preparator in the ...
https://en.wikipedia.org/wiki/Kanan_Yusif-zada
Online Donor Registry (Ontario)Online Donor Registry (Ontario)
Saudi Center for Organ Transplantation. "Saudi Center for Organ Transplantation :: Referral Center at the GCC Heath Council". ... The pancreas waitlist, however, increased by 24 patients since 2001. Heart, lung, and heart with lungs remained moderately ... Through the Malaysian Society of Transplantation in Malaysia, citizens can explore the option of organ donation. The Malaysian ... Certain religions, such as the Jehovah's Witnesses, oppose organ donation and transplantation. It is considerably expensive to ...
https://en.wikipedia.org/wiki/Online_Donor_Registry_(Ontario)
Autosomal dominant polycystic kidney diseaseAutosomal dominant polycystic kidney disease
"Autosomal dominant polycystic kidney disease and transplantation". Annals of Transplantation. 14 (4): 86-90. PMC 2843931. PMID ... pancreas, and arachnoid membrane, as well as other abnormalities, such as intracranial aneurysms and dolichoectasias, aortic ... Kidney transplantation is accepted as the preferred treatment for ADPKD patients with ESRD. Among American patients on the ... Over 50% of patients with ADPKD eventually develop end stage kidney disease and require dialysis or kidney transplantation. ...
https://en.wikipedia.org/wiki/Autosomal_dominant_polycystic_kidney_disease
ExenatideExenatide
Once blood sugar levels decrease closer to normal values, the pancreas response to produce insulin is reduced; other drugs ( ... Cell Transplantation. 26 (9): 1560-1571. doi:10.1177/0963689717721234. PMC 5680957. PMID 29113464. Bailey, Suzanne (2021-11-30 ... Exenatide is believed to facilitate glucose control in at least five ways: Exenatide augments pancreas response (i.e. increases ... It works by increasing insulin release from the pancreas and decreases excessive glucagon release. Exenatide was approved for ...
https://en.wikipedia.org/wiki/Exenatide
IPEX syndromeIPEX syndrome
The second hallmark is type 1 diabetes (T1D) and the worst complication of it is destruction of pancreas confirmed by ... Management for IPEX has seen limited success in treating the syndrome by bone marrow transplantation. The most representative ...
https://en.wikipedia.org/wiki/IPEX_syndrome
Xia SuishengXia Suisheng
He later researched transplantation of other organs. He successfully performed China's first pancreas transplantation in 1984, ... China's first spleen transplantation in 1989, and Asia's first successful multiple abdominal organ transplantation in 1995. Xia ... Xia Suisheng (Chinese: 夏穗生; 19 April 1924 - 16 April 2019) was a Chinese surgeon and pioneer in organ transplantation. Xia was ... In 1972, Xia began experimenting with liver transplantation on dogs. He and his colleagues spent five years performing 130 dog ...
https://en.wikipedia.org/wiki/Xia_Suisheng
University of Mississippi Medical CenterUniversity of Mississippi Medical Center
Hardy's research on transplantation, consisting of primate studies during the previous nine years. Daniel Jones, physician, ... pancreas, cornea and bone marrow transplant programs; a comprehensive stroke unit; state-of-the-art radiological imaging ...
https://en.wikipedia.org/wiki/University_of_Mississippi_Medical_Center
James Shapiro (physician)James Shapiro (physician)
He also served as the President of the International Pancreas and Islet Transplantation Association (IPITA), as well as serving ... kidney and pancreas transplantations as part of the Canadian National Transplant Research Project. His busy research lab is ... He leads the Edmonton team, which is the largest islet transplantation team worldwide. Shapiro also led the first-in-human stem ... 2000). "Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive ...
https://en.wikipedia.org/wiki/James_Shapiro_(physician)
Physical oncologyPhysical oncology
... for example human cancer of the pancreas in the mouse pancreas - is one of the best experimental models. The link between the ... "Reprogramming of a melanoma genome by nuclear transplantation". Genes & Development. 18 (15): 1875-1885. doi:10.1101/gad. ... More than 90% of cancers (breast, prostate, colon / rectum, bronchi, pancreas, etc.) arise from these epithelia after a long ... a liver cell does not look like a pancreas cell at all because it does not express the same genes (yet all present in the ...
https://en.wikipedia.org/wiki/Physical_oncology
Glossary of diabetesGlossary of diabetes
Islet cell Transplantation Moving the beta (islet) cells from a donor pancreas and putting them into a person whose pancreas ... Segmental transplantation A surgical procedure in which a part of a pancreas that contains insulin-producing cells is placed in ... Pancreas transplant A surgical procedure that involves replacing the pancreas of a person who has diabetes with a healthy ... Beta cell transplantation See: Islet cell transplantation. Biosynthetic human insulin A man-made insulin that is chemically ...
https://en.wikipedia.org/wiki/Glossary_of_diabetes
Hinrich Bitter-SuermannHinrich Bitter-Suermann
... liver and pancreas transplantation. He initiated successfully the Liver Transplant Program for Atlantic Canada, then Canada's ... His research interests focused on induction of transplantation tolerance by spleen transplants in rats and the preservation of ... and islet transplantation in rats. At the same time he collaborated with Ethan M.Shevach as visiting scientist at the National ... Splenic transplantation in rats NIH grants #AI 16106 and AM 27469 "Election Returns, 1998 (Chester-St. Margaret's)" (PDF). ...
https://en.wikipedia.org/wiki/Hinrich_Bitter-Suermann
Stem cell markerStem cell marker
March 1997). "Factors predicting morbidity following hematopoietic stem cell transplantation". Bone Marrow Transplantation. 19 ... July 2006). "Presence of endocrine and exocrine markers in EGFP-positive cells from the developing pancreas of a nestin/EGFP ... Bone Marrow Transplantation. 37 (5): 499-502. doi:10.1038/sj.bmt.1705262. PMID 16415895. Suzuki A, Nakauchi H, Taniguchi H ( ... Transplantation. 78 (4): 516-23. doi:10.1097/01.TP.0000128854.20831.6F. PMID 15446309. S2CID 84476256. Valente T, Junyent F, ...
https://en.wikipedia.org/wiki/Stem_cell_marker
Organ printingOrgan printing
Although this approach may be less expensive than traditional surgical transplantation, there is skepticism in regards to ... two years for a pancreas, and five years for a kidney. This is a significant increase from the 1990s, when a patient could wait ... and insures that the artificially formed structure can be broken down upon successful transplantation, to be replaced by a ... Warsaw Foundation for Research and Development of Science in Poland have been working on creating a fully artificial pancreas ...
https://en.wikipedia.org/wiki/Organ_printing
Soybean agglutininSoybean agglutinin
Consumption of soybean agglutinin resulted in a depletion of lipid and an overgrowth of small intestine and pancreas in rats. ... Cells fractionated by SBA do not produce graft vs host disease and can be used in bone marrow transplantation across ...
https://en.wikipedia.org/wiki/Soybean_agglutinin
Table 2 - Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation - Volume 23, Number...
Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation Monique A. Foster. , Lauren M ... Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation. ...
https://wwwnc.cdc.gov/eid/article/23/4/16-1532-t2
HDCN: Article by Gaston et al. <b>Kidney and pancreas transplantation</b> ...HDCN: Article by Gaston et al. <b>Kidney and pancreas transplantation</b> ...
Kidney and pancreas transplantation Am J Transplant (Apr) 3s4:74-78, 2003 ... Am J Transplantation home page If you are a paid subscriber to HDCN, the full text of this review article is available to you ...
https://www.hdcn.com/03/004atga.htm
When to Refer a Diabetic Patient for Pancreas Transplantation | UH Transplant Institute | University Hospitals Cleveland...When to Refer a Diabetic Patient for Pancreas Transplantation | UH Transplant Institute | University Hospitals Cleveland...
Why Pancreas Transplantation?. The goal of pancreas transplantation is to replace insulin-producing cells in order to control ... Islet cell transplantation: In this situation, only the insulin-producing cells of the pancreas are given to the patient. ... 2PAK: Pancreas after kidney transplantation: Patients with diabetes mellitus who have had a kidney transplant performed for end ... 3PTA: Pancreas transplantation alone: Patients with diabetes mellitus who have good kidney function but have severe difficulty ...
https://www.uhhospitals.org/for-clinicians/specialties/surgery/divisions/transplant/referring-physicians/when-to-refer-a-diabetic-for-pancreas-transplant
Pancreas transplantation<...
Pancreas transplantation. / Dubernard, J. M.; Bosi, E.. In: Transplantation Proceedings, Vol. 15, No. 4 SUPPL. 1-2, 1983, p. ... Dubernard, J. M. ; Bosi, E. / Pancreas transplantation. In: Transplantation Proceedings. 1983 ; Vol. 15, No. 4 SUPPL. 1-2. pp. ... Dubernard, J. M., & Bosi, E. (1983). Pancreas transplantation. Transplantation Proceedings, 15(4 SUPPL. 1-2), 2676-2677. ... Dubernard, JM & Bosi, E 1983, Pancreas transplantation, Transplantation Proceedings, vol. 15, no. 4 SUPPL. 1-2, pp. 2676-2677 ...
https://moh-it.pure.elsevier.com/en/publications/pancreas-transplantation
Early enteral nutrition after Pancreas Kidney Transplantation (PKTx) with enteral drainage (a pilot study in five patients) |...Early enteral nutrition after Pancreas Kidney Transplantation (PKTx) with enteral drainage (a pilot study in five patients) |...
Agthé, D., Mueller, A., Full, H. et al. Early enteral nutrition after Pancreas Kidney Transplantation (PKTx) with enteral ... Early enteral nutrition after Pancreas Kidney Transplantation (PKTx) with enteral drainage (a pilot study in five patients). *D ... Early enteral nutrition after Pancreas Kidney Transplantation (PKTx) with enteral drainage (a pilot study in five patients) ... Little data exist, so far, about the use in pancreas-kidney-transplant recipients with enteral drainage. Because of the enteral ...
https://ccforum.biomedcentral.com/articles/10.1186/cc885
Sponsored Symposia: Molecular-level insights in Kidney & Pancreas Care: Prospera Deep-Dive Sponsored by Natera | American...Sponsored Symposia: Molecular-level insights in Kidney & Pancreas Care: Prospera Deep-Dive Sponsored by Natera | American...
Specifically, early promising Prospera use in kidney and pancreas patients will be highlighted. Furthermore, recent experiences ... this rebroadcasted session explores the new applications of cell-free and genomic DNA in kidney and pancreas transplant care ... Originally presented at the AST Cutting Edge of Transplantation (CEoT) Meeting in February 2021, ... ASt/AJT Journal Club on "Simultaneous pancreas-kidney transplantation in Caucasian versus African American patients...". July ...
https://www.myast.org/calendar-events/sponsored-symposia-molecular-level-insights-kidney-pancreas-care-prospera-deep-dive
Imaging of pancreas transplantation and its complications | Insights into Imaging | Full TextImaging of pancreas transplantation and its complications | Insights into Imaging | Full Text
... radiologists must be aware of the transplantation technique, pancreas-graft imaging and postoperative complications. We present ... Pancreas transplantation is an effective treatment for type 1 diabetes mellitus and is being increasingly performed worldwide. ... normal pancreas-graft imaging appearances and the imaging features of postoperative complications. ... after SPK transplantation. The pancreas is placed laterally in the pelvis, on the right side, with the attached donors ...
https://insightsimaging.springeropen.com/articles/10.1007/s13244-010-0041-8/figures/6
A prospective, randomized, multi-center trial of antibody induction therapy in simultaneous pancreas-kidney transplantation |...A prospective, randomized, multi-center trial of antibody induction therapy in simultaneous pancreas-kidney transplantation |...
A prospective, randomized, multi-center trial of antibody induction therapy in simultaneous pancreas-kidney transplantation. Go ...
https://emmes.com/publications/1018
Pancreas Transplant | MedlinePlusPancreas Transplant | MedlinePlus
A pancreas transplant is surgery to place a healthy pancreas from a donor into a person with a diseased pancreas. Learn more. ... Getting a New Pancreas: Facts about Pancreas Transplants (American Society of Transplantation) - PDF ... A pancreas transplant is surgery to place a healthy pancreas from a donor into a person with a diseased pancreas. It is mostly ... Kidney-Pancreas Transplant (National Kidney Foundation) * Pancreas transplant - slideshow (Medical Encyclopedia) Also in ...
https://medlineplus.gov/pancreastransplantation.html
Expanding the donor pool in pancreas transplantation. - Nuffield Department of Surgical Sciences
... update on long-term outcomes of live pancreas donors, as well as efforts at objectively assessing donor risk. SUMMARY: It has ... recent additions to the cohort have been increase in pancreases from donors after cardiac death (controlled and uncontrolled), ... to increase the number of pancreases available for transplant. This review summarizes the cumulative efforts of various centers ... limiting further damage to these vulnerable grafts is important in improving utilization as well as successful transplantation. ...
https://www.nds.ox.ac.uk/publications/1095962
Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas TransplantationTransmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation
Title : Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation Personal Author(s) : ... Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation. ... Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation ... transmission through organ transplantation has not been reported. In August 2015, state health officials in Texas, USA, were ...
https://stacks.cdc.gov/view/cdc/45027
Pancreas Transplantation Guidelines: Guidelines SummaryPancreas Transplantation Guidelines: Guidelines Summary
The first successful pancreas transplantation in conjunction with a simultaneous kidney transplantation was performed by W. ... The purpose of pancreas transplantation is to ameliorate type I diabetes and produce complete insulin independence. ... encoded search term (Pancreas Transplantation) and Pancreas Transplantation What to Read Next on Medscape ... Pancreas After Islet Transplantation: A First Report of the International Pancreas Transplant Registry. Am J Transplant. 2016 ...
https://emedicine.staging.medscape.com/article/429408-guidelines
Diabetic Nephropathy Treatment & Management: Approach Considerations, Glycemic Control, Management of HypertensionDiabetic Nephropathy Treatment & Management: Approach Considerations, Glycemic Control, Management of Hypertension
... simultaneous kidney and pancreas transplantation and (2) first kidney and then pancreas transplantation (the latter is usually ... Kidney transplantation and kidney-pancreas transplantation. Except in patients with severe macroangiopathic complications, ... Transplantation of the more immunogenic pancreas appears to have a higher risk of biopsy-proven acute kidney graft rejection ... Indications for pancreas transplantation in nonuremic patients have not been established. Generally, it is offered to patients ...
https://www.medscape.com/answers/238946-42608/where-can-more-information-on-diabetes-complications-be-found
Kidney and Pancreas Transplantation | SurgeryKidney and Pancreas Transplantation | Surgery
Weill Cornell Medicine has combined its renowned expertise in kidney and pancreas transplantation with a patient-centered ... For more than 50 years, Weill Cornell Medicine has combined its renowned expertise in kidney and pancreas transplantation with ... Our expertise extends to pancreas transplantation for patients with life-threatening complications of Type 1 diabetes mellitus ... The Kidney and Pancreas Transplant program at Weill Cornell Medicine is the largest of its kind in the United States, with more ...
https://surgery.weill.cornell.edu/surgical-services/kidney-and-pancreas-transplantation
Figure 2 - Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation - Volume 23,...
Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation Monique A. Foster. , Lauren M ... Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation. ... Clinical timeline of HAV infection among a multi-visceral organ transplantation recipient and infected healthcare workers, ...
https://wwwnc-origin.cdc.gov/eid/article/23/4/16-1532-f2
Diabetes and Transplantation - Diabetes CanadaDiabetes and Transplantation - Diabetes Canada
Reported graft survival rates according to type of pancreas transplantation (6). PAK, pancreas after kidney; PTA, pancreas ... 4. Pancreas Transplantation. Pancreas transplantation can result in complete independence from exogenous insulin in the ... 6. Risks Associated with Pancreas and Islet Transplantation. Pancreas transplantation represents major abdominal surgery and is ... Metabolic long-term follow-up of functioning simultaneous pancreas-kidney transplantation versus pancreas transplantation alone ...
https://www.diabetes.ca/health-care-providers/clinical-practice-guidelines/chapter-20
Pancreas, Islet and Stem Cell Transplantation for Diabetes - Voirol BuchhandlungPancreas, Islet and Stem Cell Transplantation for Diabetes - Voirol Buchhandlung
This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and ... This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and ... This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and ... pancreatic stem cell transplantation, reflecting recent advances in the field, including the growing interest in stem cell ...
https://www.voirol-buch.ch/pancreas-islet-and-stem-cell-transplantation-for-diabetes-isbn-978-0-19-956586-3
Ton Rabelink, Instructor | CourseraTon Rabelink, Instructor | Coursera
In 2004 he moved to Leiden University Medical Center and became head of the department of Nephrology and Transplantation and in ...
https://www.coursera.org/instructor/~14427399
Kidney and Pancreas Transplant - Einstein HealthKidney and Pancreas Transplant - Einstein Health
Kidney and Pancreas Transplant. Kidney & Pancreas Disease & Transplantation. Kidney & Pancreas Disease & Transplantation Home * ... Home / Services / Kidney & Pancreas Disease & Transplantation / Conditions & Treatments / ... At Einstein, we have clinical expertise in all core domains of organ disease and transplantation and are actively invested in ... Patients must schedule a kidney transplant evaluation at one of Einsteins kidney transplantation locations in order to become ...
https://www.einstein.edu/kidney/conditions/transplant
Clinical Associate Professor & Director of Kidney and Pancreas - Transplantation & Hepatobiliary Surgery - HR CalendarClinical Associate Professor & Director of Kidney and Pancreas - Transplantation & Hepatobiliary Surgery - HR Calendar
Clinical Associate Professor & Director of Kidney and Pancreas - Transplantation & Hepatobiliary Surgery. May 28, 2021 - June ...
https://calendar.hr.ufl.edu/event/clinical-associate-professor-director-of-kidney-and-pancreas-transplantation-hepatobiliary-surgery/
Predicting early graft loss in pancreas transplantation using novel imaging techniques: are we there yet? | Hepatobiliary Surg...Predicting early graft loss in pancreas transplantation using novel imaging techniques: are we there yet? | Hepatobiliary Surg...
Predicting early graft loss in pancreas transplantation using novel imaging techniques: are we there yet? ... Predicting early graft loss in pancreas transplantation using novel imaging techniques: ar ...
https://pesquisa.bvsalud.org/portal/resource/es/mdl-37124702
IMSEAR at SEARO: Simultaneous pancreas and kidney transplantation for end-stage renal failure secondary to diabetic nephropathy...
Simultaneous pancreas and kidney transplantation for end-stage renal failure secondary to diabetic nephropathy : principles and ... Simultaneous pancreas and kidney transplantation for end-stage renal failure secondary to diabetic nephropathy : principles and ... Over the last three decades, increasing number of patients are undergoing simultaneous pancreas and kidney transplantation ( ... most common cause of renal failure in the United Kingdom where majority of the patients were managed by renal transplantation ...
https://imsear.searo.who.int/handle/123456789/45908
Frequently Asked Questions about Pancreas Transplants | BIDMC of BostonFrequently Asked Questions about Pancreas Transplants | BIDMC of Boston
What is the success rate for pancreas transplantation? Pancreas transplant is successful in about 90 percent of patients who no ... transplantation? For certain patients with type 1 diabetes, research shows that pancreas after kidney (PAK) transplantation ... How will a pancreas transplant benefit me? One of the biggest benefits to a pancreas transplant for people with type 1 diabetes ... Some patients with diabetes, who have already received a donor kidney, consider pancreas transplantation to protect their new ...
https://www.bidmc.org/centers-and-departments/transplant-institute/pancreas-transplant/frequently-asked-questions-about-pancreas-transplants
Publications | Infectious Diseases Pathology Branch (IDPB) | CDCPublications | Infectious Diseases Pathology Branch (IDPB) | CDC
Transmission of Hepatitis A Virus through Combined Liver-Small Intestine-Pancreas Transplantation. EID. 2017;April 23(4):590-6. ... A Fatal Case of Disseminated Microsporidiosis Due to Anncaliia algerae in a Renal and Pancreas Allograft Recipient.external ...
https://www.cdc.gov/ncezid/dhcpp/idpb/publications/index.html
San Diego Organ Transplant Surgery | Sharp HealthCareSan Diego Organ Transplant Surgery | Sharp HealthCare
Sharp HealthCare has been at the forefront of organ transplantation in San Diego. Our commitment to you begins long before and ... Kidney and pancreas transplantation.. For more than 30 years, Sharp has led the way with its Kidney and Pancreas Transplant ... Heart transplantation.. At Sharp, we are proud to have pioneered the first heart transplant surgery in San Diego. Led by a ... Our transplant teams have helped change the lives of many patients through kidney, heart, pancreas and multi-organ transplant ...
https://www.sharp.com/services/transplant/
New Drugs, Devices Mount Assault On Diabetes | The Scientist Magazine®New Drugs, Devices Mount Assault On Diabetes | The Scientist Magazine®
TRANSPLANT SUCCESS: Transplantation of the whole pancreas should be performed more often, s ... TRANSPLANT SUCCESS: Transplantation of the whole pancreas should be performed more often, surgeon David Sutherland suggests.. ... TRANSPLANT SUCCESS: Transplantation of the whole pancreas should be performed more often, s. Steve Bunk ... "Transplantation is another area.". R&D ADVANCES: New medications, delivery systems, and transplantation are all making progress ...
https://www.the-scientist.com/news/new-drugs-devices-mount-assault-on-diabetes-57295
Dr. Pradip Chakrabarti:: Pancreas Transplant Surgeon, India, Kolkata, Pancreas Transplantation in diabetes mellitus, Surgery,...
... is a skilled kidney and pancreas transplant surgeon who performs laparoscopic nephrectomies and has extensive experience in ... PANCREAS TRANSPLANTATION: Pancreas transplantation was first used for the treatment of diabetes in humans in 1966. The rates of ... PANCREAS TRANSPLANTATION. Pancreas transplantation in diabetes mellitus :. INTRODUCTION:. The Diabetes Control and Complication ... The graft survival rate of pancreas transplantation alone is lower than that for kidney-pancreas transplantation because, at ...
http://kolkatakidneytransplant.in/adver/109177pancreas.html
Superior Long-term Survival for Simultaneous Pancreas-Kidney Transplantation as Renal Replacement Therapy: 30-Year Follow-up of...Superior Long-term Survival for Simultaneous Pancreas-Kidney Transplantation as Renal Replacement Therapy: 30-Year Follow-up of...
Superior Long-term Survival for Simultaneous Pancreas-Kidney Transplantation as Renal Replacement Therapy: 30-Year Follow-up of ...
http://glucosolve.com/superior-long-term-survival-for-simultaneous-pancreas-kidney-transplantation-as-renal-replacement-therapy-30-year-follow-up-of-a-nationwide-cohort/
Annals of Transplantation | Usefulness of Pancreas Donor Risk Index and Pre-Procurement Pancreas Allocation Suitability Score:...Annals of Transplantation | Usefulness of Pancreas Donor Risk Index and Pre-Procurement Pancreas Allocation Suitability Score:...
... simultaneous pancreas-kidney transplantation and 37 (9.1%) pancreas transplantation alone or pancreas after kidney. The ... MATERIAL AND METHODS:From February 1998 to September 2015, 407 pancreas transplantations were performed in Poland: 370 (90.9%) ... Recent data discourage use of PDRI to predict pancreas graft survival. The aim of the present study was to assess PDRI and P- ... Univariate analysis revealed donor age, body mass index (BMI), and P-PASS to be significant risk factors for 1-year pancreas ...
https://annalsoftransplantation.com/abstract/index/idArt/909654
American Society of TranLiver TransplantationSurgeryTransplantsCells in the pancreasDiabetesPancreaticInternational PancreasOrgansComplicationsWhole pancreasSimultaneous pancreasEligible For a Pancreas TransplantCell TransplantationDonorsHeart TransplantationField of transplantationLung TransplantationKidneysDiabeticNephrologyRecipientsIsletsBone marrowHuman pancreasKidney-pancreasTherapiesCadavericInsulin independenceImmunosuppressionDonor pancreasRejectionOutcomesPatientsSurvivalSolid organOrgan DonationClinical TrialsRenal failure19841962ESOTTypeHospitalDonationVascular disease
American Society of Tran2
  • The American Society of Transplantation is supportive of the proposal and offers the following comments for consideration: We suggest using age and weight to make this determination. (hrsa.gov)
  • The Practice Guidelines Committee of the American Society of Transplantation and Cellular Therapy (ASTCT) partnered with its Transplant Infectious Disease Special Interest Group (TID-SIG) to update its 2009 compendium-style infectious disease guidelines for hematopoietic cell transplantation (HCT). (bvsalud.org)
Liver Transplantation5
  • The Liver transplantation program hosts a team of surgeons, doctors, nurses and other health professionals, who take care of the patient and the patient's family through the transplant process. (manipalhospitals.com)
  • Liver transplantation is a surgical procedure, which involves replacing a non-functional liver with a healthy liver. (manipalhospitals.com)
  • Manipal Hospital is the best Liver transplantation and hepato-pancreato-biliary surgery hospital in Baner Pune specialised in the diagnosis and surgical management of an array of disorders related to the pancreas, bile ducts, liver, and gallbladder. (manipalhospitals.com)
  • Besides, Manipal Hospital's liver transplant team is experienced in various aspects of a liver transplant, such as deceased donor liver transplantation, living donor liver transplantation, and paediatric liver transplant, combined kidney and liver transplant, etc. (manipalhospitals.com)
  • 1989: The first liver transplantation from a living-related donor was performed. (medscape.com)
Surgery7
  • A pancreas transplant is surgery to place a healthy pancreas from a donor into a person with a diseased pancreas. (medlineplus.gov)
  • VCA has opened a new era in the field of transplantation, reconstructive and restorative surgery. (esot.org)
  • Dr Lee is formally trained in liver transplants, kidney transplants and simultaneous pancreas kidney transplants in addition to complex hepatobiliary pancreatic surgery. (mountelizabeth.com.sg)
  • René Adam is Head of the Hepato-Biliary Surgery, Cancer and Transplantation Unit at Paul Brousse Hospital, Villejuif, France. (esot.org)
  • Professor Adam's main fields of activity and research are surgery of the liver, biliary tract and pancreas, and hepatic transplantation. (esot.org)
  • Hepato-pancreato-biliary surgery involves a surgical procedure of the liver, gallbladder and the pancreas. (manipalhospitals.com)
  • Professor Henry Pleass studied medicine as an undergraduate at the University of Newcastle Upon-Tyne, England and trained in general and transplantation surgery in the North East of England, Edinburgh Scotland and Sydney Australia. (amj.net.au)
Transplants10
  • An experimental procedure called islet cell transplantation transplants only the parts of the pancreas that make insulin. (medlineplus.gov)
  • People who have transplants must take drugs to keep their body from rejecting the new pancreas for the rest of their lives. (medlineplus.gov)
  • The Kidney and Pancreas Transplant program at Weill Cornell Medicine is the largest of its kind in the United States, with more than 5,000 kidney transplants under our belt. (cornell.edu)
  • For certain people with type 1 diabetes, pancreas or islet transplants may help stabilize blood glucose levels. (diabetes.ca)
  • In a subsequent analysis that eliminated these multiple listings, there were no significant differences in mortality rates between patients on the waiting list and those receiving pancreas-after-kidney or pancreas-alone transplants. (kolkatakidneytransplant.in)
  • More than 23,000 pancreas transplants have now been reported to the International Transplant Registry (IPTR). (springeropen.com)
  • The first whole-pancreas transplant was performed in the University of Minnesota, USA in 1966 [ 3 ] and, with improvements in surgical technique and immunosuppressive therapy, increasing numbers of successful transplants are performed. (springeropen.com)
  • In the UK the number of pancreas transplants has steadily increased from 30, in 1998-1999, to 209, in 2007-2008. (springeropen.com)
  • Of 209 pancreas transplants performed in the UK in 2007-2008, 173 (83%) were SPK transplants donated following brain death (DBD), although an increasing number of pancreases in the UK are donated following cardiac death (DCD). (springeropen.com)
  • Alternatively, solitary pancreas transplants may be performed [ 5 ], usually in patients who have already had a kidney transplant often from a living donor: so-called pancreas after kidney transplants (PAK). (springeropen.com)
Cells in the pancreas4
  • We were the first center in the New York Tri-State area to have performed successful human islet cell transplantation, a minimally invasive procedure to isolate the insulin-producing cells in the pancreas and implant them in a patient in order to improve control and reduce complications of Type 1 diabetes. (cornell.edu)
  • Usually, the body's own immune system - which normally fights harmful bacteria and viruses - destroys the insulin-producing (islet) cells in the pancreas. (mayoclinic.org)
  • To develop a successful approach to protect beta cells, we must understand how and why T cells are directed to specifically destroy insulin-producing cells in the pancreas while sparing adjacent hormone-producing cells including alpha, delta, and epsilon cells. (frontiersin.org)
  • Islets are clusters of cells in the pancreas that produce insulin, a hormone the body requires to use glucose (sugar) as a source of energy. (nih.gov)
Diabetes41
  • Simultaneous kidney and pancreas transplantation: In this situation, individuals have developed end-stage renal disease due to diabetes. (uhhospitals.org)
  • Pancreas after kidney transplantation: Patients with diabetes mellitus who have had a kidney transplant performed for end-stage renal disease can potentially be a suitable candidate to receive a pancreas transplant. (uhhospitals.org)
  • Also, the pancreas transplant can offer some protection to the kidney transplant from the effects of diabetes and possible failure of the kidney transplant due to diabetes. (uhhospitals.org)
  • Pancreas transplantation alone: Patients with diabetes mellitus who have good kidney function but have severe difficulty in controlling their blood glucose levels and who potentially experience hypoglycemic unawareness are eligible for this type of transplantation. (uhhospitals.org)
  • Lessons From Pancreas Transplantation in Type 1 Diabetes: Recurrence of Islet Autoimmunity. (medscape.com)
  • Kerr HR, Hatipoglu B, Krishnamurthi V. Pancreas transplant for diabetes mellitus. (medscape.com)
  • Our expertise extends to pancreas transplantation for patients with life-threatening complications of Type 1 diabetes mellitus. (cornell.edu)
  • For people with diabetes and end stage renal disease, kidney transplantation improves long-term outcomes compared with dialysis. (diabetes.ca)
  • For people with type 1 diabetes and end stage renal disease, simultaneous pancreas-kidney transplantation can improve kidney graft survival and result in prolonged insulin independence. (diabetes.ca)
  • For people with type 1 diabetes, pancreas or islet allotransplantation improves glycemic control, prevents severe hypoglycemia even in the absence of complete insulin independence, but with the risks of long-term immunosuppression. (diabetes.ca)
  • Post-transplant diabetes is common after solid organ transplantation and is associated with increased risk for mortality, cardiovascular disease and graft loss. (diabetes.ca)
  • Restoring endogenous insulin secretion by whole pancreas or islet transplantation has been established as an alternative to insulin injection therapy in select individuals with type 1 diabetes (1,2) . (diabetes.ca)
  • More broadly, diabetes is an important clinical issue in solid organ transplantation. (diabetes.ca)
  • New cases of diabetes developing after solid organ transplantation-post-transplant diabetes mellitus (PTDM)-are common and associated with reduced patient and graft survival. (diabetes.ca)
  • Over the last three decades, increasing number of patients are undergoing simultaneous pancreas and kidney transplantation (SPKT) because of its advantages, which renders the patient both dialysis and insulin-independent, halts the progression of complications of diabetes, thereby improves the quality of life, survival and has proven to be cost-effective. (who.int)
  • People with type 1 diabetes (inability to produce insulin), chronic pancreatitis or traumatic loss of pancreas may be candidates for a pancreas transplant. (bidmc.org)
  • However, those with type 2 diabetes, where the body is unable to use the insulin it produces, generally do not benefit from a pancreas transplant. (bidmc.org)
  • One of the biggest benefits to a pancreas transplant for people with type 1 diabetes is lifestyle improvement. (bidmc.org)
  • Will a pancreas transplant help reduce my risk of vascular disease, retinopathy, and other health concerns brought on by diabetes? (bidmc.org)
  • A pancreas transplant is generally not for patients who have a mild case of type 1 diabetes that responds well to insulin therapy and certain diet restrictions. (bidmc.org)
  • Other patients consider pancreas transplant because they have "brittle" diabetes, with very severe and sudden symptoms and complications from type 1 diabetes. (bidmc.org)
  • New medications, delivery systems, and transplantation are all making progress in combating diabetes, says CDC's Frank Vinicor. (the-scientist.com)
  • This topic will briefly review the history, techniques, and clinical results of pancreas and pancreatic islet transplantation in hyperglycaemic patients with long-standing type 1 diabetes mellitus, with a focus upon transplantation of pancreatic tissue alone. (kolkatakidneytransplant.in)
  • Pancreas transplantation was first used for the treatment of diabetes in humans in 1966. (kolkatakidneytransplant.in)
  • It has been reported that in patients with preserved renal function, survival after pancreas transplant may be worse than for patients on the waiting list receiving conventional therapy for diabetes. (kolkatakidneytransplant.in)
  • This was reported in a retrospective study of 11,572 patients with diabetes on a waiting list for pancreas transplantation (pancreas-only, pancreas-after-kidney, or simultaneous pancreas-kidney). (kolkatakidneytransplant.in)
  • Diabetes is the most common cause of kidney and pancreas transplantation. (who.int)
  • The first international, multicenter trial of the Edmonton Protocol - a standardized approach to the transplantation of insulin-producing islets - demonstrates that this may be an appropriate therapy that can dramatically benefit certain patients with severe complications of Type 1 diabetes mellitus. (nih.gov)
  • The results of the trial show the feasibility and reproducibility of islet transplantation using the Edmonton Protocol and has promising implications for the future of treating type 1 diabetes," says NIH Director Elias A. Zerhouni, M.D. (nih.gov)
  • Dr. Shapiro and the ITN research team have improved our understanding of the potential of islet transplantation for certain patients with Type 1 diabetes," says NIAID Director Anthony S. Fauci, M.D. "Ongoing studies will further define the clinical utility of this approach. (nih.gov)
  • In the last few decades, doctors have been able to treat Type 1 diabetes with pancreas transplantation. (nih.gov)
  • Many people with diabetes who have taken daily insulin injections for years have achieved total insulin independence after pancreas transplantation - often for years after the transplant. (nih.gov)
  • Biology, development, and function of the endocrine pancreas and clinical studies on islet transplantation for type 1 diabetes treatment. (nih.gov)
  • The annual number of patients initiating dialysis has grown substantially over the past decade ( 2 ) and is expected to increase further, consequent to the shortage of donors for renal transplantation ( 3 , 4 ), lack of therapies to reverse the progression of renal failure, and the growing prevalence of diabetes and hypertension, the leading causes of progressive chronic kidney disease ( 2 ). (asnjournals.org)
  • Pancreas transplantation is a surgical treatment for diabetes mellitus. (springeropen.com)
  • Pancreas transplantation is a surgical treatment for diabetes mellitus (DM). (springeropen.com)
  • Pancreatic islet transplantation as a treatment for type 1 diabetes received a major impetus with the development of the Edmonton protocol and recent clinical trials demonstrating long-term insulin independence out beyond 5 years after transplantation ( 1 - 4 ), although encouraging this therapy will always be limited by the relatively small number of organ donors available for islet isolation. (diabetesjournals.org)
  • Although great progress has been made in establishing allogeneic islet transplantation from deceased donors as the standard of care for those with the most labile diabetes, it is also clear that the deceased donor organ supply cannot possibly treat all those who could benefit from restoration of a normal beta cell mass, especially if immunosuppression were not required. (edu.au)
  • Against this background, the International Pancreas and Islet Transplant Association in collaboration with the Harvard Stem Cell Institute, the Juvenile Diabetes Research Foundation (JDRF), and the Helmsley Foundation held a 2-day Key Opinion Leaders Meeting in Boston in 2016 to bring together experts in generating and transplanting beta cells derived from stem cells. (edu.au)
  • However, scarring also affects the heart and kidneys leading to heart and renal failure, the bone marrow leading to blood disease, the pancreas leading to diabetes, the blood vessels leading to strokes and heart attacks and the brain in multiple sclerosis and motor neurone disease. (ukri.org)
  • In Type 1 diabetes, the islet cells produced by the pancreas are destroyed by an autoimmune reaction. (newatlas.com)
Pancreatic7
  • Coronal reformatted MDCT image shows homogeneous enhancement of the pancreatic ( white asterisk ) and renal grafts ( black asterisk ) after SPK transplantation. (springeropen.com)
  • This new edition provides an authoritative account of the current status of whole organ pancreas transplantation and islet and pancreatic stem cell transplantation, reflecting recent advances in the field, including the growing interest in stem cell research applicable to this condition. (voirol-buch.ch)
  • As a result, the number of pancreatic transplantations has steadily increased each year. (kolkatakidneytransplant.in)
  • He is also member of several international societies, including the European Society of Organ Transplantation (ESOT), and the International Hepato-Pancreatic and Biliary Association (IHPBA). (esot.org)
  • A Whipple procedure (also called pancreaticoduodenectomy) is a complex, yet lifesaving surgical procedure used to treat pancreatic cancer, and other disease and disorders of the pancreas, bile duct, duodenum etc. (manipalhospitals.com)
  • Autologous islet cell transplantation isn't commonly performed in chronic pancreatitis patients who are having pancreatic resection, typically because of the need for multidisciplinary coordination of care. (medpagetoday.com)
  • The injection of MSCs directly into pancreatic islets is not feasible because the pancreas is fragile and releases highly toxic enzymes when manipulated. (diabetesresearchconnection.org)
International Pancreas2
  • Pancreas After Islet Transplantation: A First Report of the International Pancreas Transplant Registry. (medscape.com)
  • He is also a member of the International Pancreas & Islet Transplantation Association and The Transplantation Society. (mountelizabeth.com.sg)
Organs17
  • A vehement rejection on ethical grounds of anything but uncompensated donation-once the professional norm-has slowly been replaced by an open debate of plans that offer financial rewards to persons willing to have their organs, or the organs of deceased kin, taken for transplantation. (bmj.com)
  • Aside from Dr Jacobs-whose combative style and occasionally odd interventions earned few points with committee members-the only persons to speak in favour of financial incentives to increase the supply of organs for transplantation were Dr Marvin Brams (University of Delaware, College of Urban Affairs and Public Policy) and kidney recipient Peter Dobrovitz. (bmj.com)
  • Among the opponents to monetary rewards for organs were representatives from the US Department of Health and Human Services, the American Society of Transplant Surgeons, the American Medical Association, the North American Transplant Coordinator's Organisation, the American Academy of Pediatrics, the National Association of Patients on Hemodialysis and Transplantation, Inc and the National Kidney Foundation. (bmj.com)
  • In the years following passage, many state legislatures followed the federal government in outlawing monetary transactions related to the acquisition of organs for transplantation. (bmj.com)
  • The mission of ECTORS is to provide a forum for discussing and stimulating novel developments in the fields of cellular therapies in organ transplantation, organ regeneration and generation of new organs from stem cells and biomaterials. (esot.org)
  • Organ procurement was started as a local endeavor when facilities performing kidney transplantation recovered organs from donors in the same facility. (medscape.com)
  • As the need for organs increased and as the specialty expanded to include other solid organs (eg, heart, lung, liver, pancreas, small intestine), the need for improved sharing agreements and organ distribution was recognized. (medscape.com)
  • In the early 1980s, the development of cyclosporine made the transplantation of all organs more feasible than before. (medscape.com)
  • No centralized network was available to increase the use of donated organs, and no criteria were established to define how an individual could access transplantation. (medscape.com)
  • Occasionally, both organs (distal pancreas segment and whole kidney) may come from a living donor [ 6 ]. (springeropen.com)
  • Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
  • This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)
  • We will determine whether the biological pathways which are responsible for lung, liver or bone marrow fibrosis may also lead to scarring in other organs and whether they link expanded clusters of scarring involving the lung, liver, pancreas, kidney, bone marrow, brain, heart, gastrointestinal tract, or whether there are other genes that promote different clusters of scarring disease. (ukri.org)
  • I want to register my details on the NHS Organ Donor Register as someone whose organs/tissue may be used for transplantation after my death. (theoldsurgery-hornsey.nhs.uk)
  • Cystic fibrosis is a genetic disorder that affects the lungs, pancreas, and other organs. (cff.org)
Complications3
  • Infectious disease complications of simultaneous pancreas kidney transplantation. (nih.gov)
  • The second section of this review briefly describes the necessity for pancreas or islet transplantation to treat severe diabetic complications. (frontiersin.org)
  • Following pancreas transplantation, it is essential that any graft-related complications are diagnosed early to ensure prompt treatment and optimal survival of both graft and patient. (springeropen.com)
Whole pancreas1
  • Transplantation of the whole pancreas should be performed more often, surgeon David Sutherland suggests. (the-scientist.com)
Simultaneous pancreas4
  • ASt/AJT Journal Club on "Simultaneous pancreas-kidney transplantation in Caucasian versus African American patients. (myast.org)
  • An evidence-based analysis of simultaneous pancreas-kidney and pancreas transplantation alone. (medscape.com)
  • IMSEAR at SEARO: Simultaneous pancreas and kidney transplantation for end-stage renal failure secondary to diabetic nephropathy : principles and practice. (who.int)
  • Pancreas transplantation is most commonly performed in conjunction with a kidney transplant, a procedure referred to as simultaneous pancreas-kidney (SPK) transplantation. (springeropen.com)
Eligible For a Pancreas Transplant2
Cell Transplantation3
  • Pancreas and cell transplantation of the islets. (ksusentinel.com)
  • Combinatorial human progenitor cell transplantation optimizes islet regeneration through secretion of paracrine factors. (stemcellsportal.com)
  • A key result of our research is that local immunosuppression for cell transplantation is effective," said the lead scientist, Prof. Alessandro Grattoni. (newatlas.com)
Donors1
  • recent additions to the cohort have been increase in pancreases from donors after cardiac death (controlled and uncontrolled), update on long-term outcomes of live pancreas donors, as well as efforts at objectively assessing donor risk. (ox.ac.uk)
Heart Transplantation2
  • Heart transplantation. (sharp.com)
  • 1967: Christiaan Bernard, MD, at Groote Shuur Hospital in Cape Town, South Africa, performed the first successful heart transplantation. (medscape.com)
Field of transplantation2
  • A related goal of the Program is to enhance the University of Maryland's position as a center of distinction in the field of transplantation and by attracting sponsors to fund University of Maryland transplant initiatives in clinical practice, research, and education. (umaryland.edu)
  • As the organization and the field of transplantation grew, organ sharing became a nationwide responsibility. (medscape.com)
Lung Transplantation2
  • 1963: James Hardy, MD, at the University of Mississippi Medical Center in Jackson, Mississippi, performed the first lung transplantation. (medscape.com)
  • 1990: The first lung transplantation from a living-related donor was performed. (medscape.com)
Kidneys2
  • Scarring is often progressive, notably in the lungs, liver and kidneys where it frequently leads to death or the need for organ transplantation. (ukri.org)
  • Clinical hallmarks of VHL disease include the development of retinal and central nervous system (CNS) hemangioblastomas (blood vessel tumors), pheochromocytomas , multiple cysts in the pancreas and kidneys, and an increased risk for malignant transformation of renal cysts into renal cell carcinoma. (medscape.com)
Diabetic2
  • Ziaja J, Bozek-Pajak D, Kowalik A, Krol R, Cierpka L. Impact of pancreas transplantation on the quality of life of diabetic renal transplant recipients. (medscape.com)
  • Diabetic nephropathy is the second most common cause of renal failure in the United Kingdom where majority of the patients were managed by renal transplantation and insulin therapy in the past. (who.int)
Nephrology1
  • In 2004 he moved to Leiden University Medical Center and became head of the department of Nephrology and Transplantation and in 2010 chairman of medicine again. (coursera.org)
Recipients4
  • Little data exist, so far, about the use in pancreas-kidney-transplant recipients with enteral drainage. (biomedcentral.com)
  • The aim of this preliminary study, is to analyze the feasibility and complication rates of early enteral immunonutrition in pancreas-kidney-transplant recipients with enteral drainage. (biomedcentral.com)
  • Testifying before Gore's committee (Sub-Committee on Investigations and Oversight of the Committee on Science and Technology, US House of Representatives, Ninety-Eighth Congress, November 7, 9, 1983) were physicians, medical ethicists, directors of organ transplantation organisations, and organ recipients. (bmj.com)
  • We describe the application of a virtual crossmatch (VXM) that has resulted in a very low rate of transplantation into unintended recipients. (lww.com)
Islets2
  • The two primary avenues for beta cell replacement are transplantation of cadaveric islets or induced pluripotent stem cell (iPS)-derived beta cells. (frontiersin.org)
  • Three still require a multi-dose insulin regimen, and two patients who had a Whipple procedure never required insulin, "likely because of the functional islets in the remaining body and tail of the pancreas," they wrote. (medpagetoday.com)
Bone marrow1
  • This ability to reduce blood sugar levels correlated to ALDHhi cell engraftment in the mouse bone marrow, but not engraftment into the mouse pancreas. (stemcellsportal.com)
Human pancreas2
  • The first human pancreas transplantation was performed in 1966. (medscape.com)
  • 1997. Metabolic activation of aromatic amines by human pancreas. (cdc.gov)
Kidney-pancreas3
  • Pancreas graft survival (defined as total freedom from insulin therapy, normal fasting blood glucose concentrations, and normal or only slightly high A1C values) rates for simultaneous kidney-pancreas procedures were 86 and 54 percent at 1 and 10 years, respectively. (kolkatakidneytransplant.in)
  • The graft survival rate of pancreas transplantation alone is lower than that for kidney-pancreas transplantation because, at least in part, of the lack of a marker for pancreas rejection that is as sensitive as serum creatinine as a marker for kidney transplant rejection. (kolkatakidneytransplant.in)
  • Once these indications are met, the pre-transplant screening for cardiovascular disease is the same as for combined kidney-pancreas transplantation. (kolkatakidneytransplant.in)
Therapies1
  • Since then, we have continued to develop and offer all possible therapies for transplantation. (cornell.edu)
Cadaveric1
  • 1962: Murray performed the first cadaveric kidney transplantation. (medscape.com)
Insulin independence1
  • Both pancreas and islet transplantation can result in insulin independence and glucose stability, especially in the setting of glucose lability or frequent, severe hypoglycemia. (diabetes.ca)
Immunosuppression1
  • Immunosuppression after solid organ transplantation is complex. (medscape.com)
Donor pancreas2
  • Initially some hospitalized patients may need to take low levels of insulin so as not to stress the newly transplanted donor pancreas. (bidmc.org)
  • The donor pancreas is retrieved en bloc with the duodenum, which is transected and stapled proximally just beyond the pylorus and distally in the third part of the duodenum. (springeropen.com)
Rejection3
  • In 2017, an update to the Banff pancreas allograft rejection grading schema was published. (medscape.com)
  • Our skilled transplant surgeons also offer progressive therapeutic options not generally available through other transplantation programs, with rejection and survival rates that rival the national standards. (cornell.edu)
  • Thus, rejection is more difficult to detect with pancreas transplantation alone and anti-rejection therapy is initiated relatively later. (kolkatakidneytransplant.in)
Outcomes2
  • Our clinical programs are among the best in the country, but we continue to improve patient care quality and outcomes after transplantation. (umaryland.edu)
  • The Clinical Mission of the Program in Transplantation is to improve the health status of organ failure patients through multi-disciplinary care teams that deliver superior outcomes while facilitating patient access to transplantation and enhancing their quality of life. (umaryland.edu)
Patients10
  • Patients ages 18 to 55 with a body mass index less than 32 must meet the following criteria to be considered for pancreas transplantation. (uhhospitals.org)
  • Patients in this situation can be evaluated for a kidney and pancreas transplant performed simultaneously. (uhhospitals.org)
  • Specifically, early promising Prospera use in kidney and pancreas patients will be highlighted. (myast.org)
  • For more than 50 years, Weill Cornell Medicine has combined its renowned expertise in kidney and pancreas transplantation with a patient-centered approach to provide compassionate, world-class care that maximizes patients' quality of life, no matter how complicated their case may be. (cornell.edu)
  • Weill Cornell Medicine also performs kidney transplantations in young patients through our Center for Pediatric Transplant and Advanced Kidney and Urologic Diseases . (cornell.edu)
  • Patients must schedule a kidney transplant evaluation at one of Einstein's kidney transplantation locations in order to become eligible for a kidney transplant. (einstein.edu)
  • Our transplant teams have helped change the lives of many patients through kidney , heart , pancreas and multi-organ transplant procedures. (sharp.com)
  • In addition, some patients from the waiting list group were counted more than once because they were registered on more than one list, and 8 percent of patients on the pancreas transplant waiting lists were removed from the waiting lists and underwent a kidney transplant first, because of deteriorating kidney function. (kolkatakidneytransplant.in)
  • EPITA is established to provide a forum for those working in the field of pancreas and islet of Langerhans transplantation or any other alternative form of beta cell replacement in Europe, to exchange scientific information and views related primarily to providing the best service for patients in Europe requiring pancreas or islet transplantation. (esot.org)
  • The University of Maryland School of Medicine Program in Transplantation was created with the mission to coordinate scientific discoveries and clinical excellence, aiming to provide patients with groundbreaking treatment options. (umaryland.edu)
Survival1
  • For more than 30 years, Sharp has led the way with its Kidney and Pancreas Transplant Program, which has one of the highest survival rates in the country. (sharp.com)
Solid organ1
  • 1983: The US Food and Drug Administration (FDA) approved the use of cyclosporine in solid-organ transplantations. (medscape.com)
Organ Donation3
  • The Young Professionals in Transplantation (YPT) is the Network for Junior Transplant professionals of ESOT, representing all young transplant clinicians and scientists who are beginning a career in transplantation and organ donation. (esot.org)
  • Organ procurement is intimately tied to the history of organ transplantation and organ donation. (medscape.com)
  • While the opinions on organ donation are generally positive, there are lots of misconception surrounding organ transplantation. (isrgrajan.com)
Clinical Trials1
  • The Innovation Mission of the Program in Transplantation is to evaluate new care modalities, treatments, and basic science findings in transplantation by conducting innovative, large-scale clinical trials and translational research, which will advance the field. (umaryland.edu)
Renal failure1
  • Unawareness of severe hypoglycemia is a primary indicator for pancreas or islet transplantation and is often combined with kidney transplantation to treat renal failure. (frontiersin.org)
19841
  • The congressional hearings produced Public Law 98-507, "The National Transplantation Act" (1984), which was brought to a vote with an astonishing 90 co-sponsors from both major political parties. (bmj.com)
19621
  • After the first initially successful series of transplantations performed between 1962 and 1964, the combination of azathioprine and steroids came into widespread use and became part of the primary immunosuppressive regimen for the next 20 years. (medscape.com)
ESOT1
  • The Basic Science Committee promotes scientific issues and transplantation research within ESOT. (esot.org)
Type2
  • Currently, University Hospitals Transplant Institute does not perform this type of transplantation but will screen potential candidates and direct them to a center that performs this type of transplantation. (uhhospitals.org)
  • Type 2 DM that presents during childhood or adolescence, healthy blood sugar at 50 typically how often to check blood sugar Normal Blood Sugar as an autosomal dominant trait in which there is diminished but not blood sugar reading 90 a1c absent insulin production by the pancreas. (esaunggul.ac.id)
Hospital1
  • 1954: Joseph Murray, MD, at the Peter Bent Brigham Hospital in Boston, Massachusetts, performed the first successful living-related donor kidney transplantation. (medscape.com)
Donation2
  • EDTCO aims to support health care professionals to provide clinically effective programmes on organ and tissue donation, procurement and transplantation. (esot.org)
  • O rgan donation is the process where a person donates or gives their organ to another for transplantation. (isrgrajan.com)
Vascular disease1
  • Yes, a pancreas transplant will help reduce your risk of vascular disease, but it will not reverse any vascular disease that is present at the time of your transplant. (bidmc.org)