Oxytocin. Medical search

A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.

Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)

A nonapeptide that contains the ring of OXYTOCIN and the side chain of ARG-VASOPRESSIN with the latter determining the specific recognition of hormone receptors. Vasotocin is the non-mammalian vasopressin-like hormone or antidiuretic hormone regulating water and salt metabolism.

Antidiuretic hormones released by the NEUROHYPOPHYSIS of all vertebrates (structure varies with species) to regulate water balance and OSMOLARITY. In general, vasopressin is a nonapeptide consisting of a six-amino-acid ring with a cysteine 1 to cysteine 6 disulfide bridge or an octapeptide containing a CYSTINE. All mammals have arginine vasopressin except the pig with a lysine at position 8. Vasopressin, a vasoconstrictor, acts on the KIDNEY COLLECTING DUCTS to increase water reabsorption, increase blood volume and blood pressure.

Expulsion of milk from the mammary alveolar lumen, which is surrounded by a layer of milk-secreting EPITHELIAL CELLS and a network of myoepithelial cells. Contraction of the myoepithelial cells is regulated by neuroendocrine signals.

Hypothalamic nucleus overlying the beginning of the OPTIC TRACT.

Carrier proteins for OXYTOCIN and VASOPRESSIN. They are polypeptides of about 10-kDa, synthesized in the HYPOTHALAMUS. Neurophysin I is associated with oxytocin and neurophysin II is associated with vasopressin in their respective precursors and during transportation down the axons to the neurohypophysis (PITUITARY GLAND, POSTERIOR).

Neural tissue of the pituitary gland, also known as the neurohypophysis. It consists of the distal AXONS of neurons that produce VASOPRESSIN and OXYTOCIN in the SUPRAOPTIC NUCLEUS and the PARAVENTRICULAR NUCLEUS. These axons travel down through the MEDIAN EMINENCE, the hypothalamic infundibulum of the PITUITARY STALK, to the posterior lobe of the pituitary gland.

Contraction of the UTERINE MUSCLE.

The smooth muscle coat of the uterus, which forms the main mass of the organ.

A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.

The repetitive uterine contraction during childbirth which is associated with the progressive dilation of the uterine cervix (CERVIX UTERI). Successful labor results in the expulsion of the FETUS and PLACENTA. Obstetric labor can be spontaneous or induced (LABOR, INDUCED).

A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide. It is used as a local vasoconstrictor and hemostatic.

The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.

The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Nucleus in the anterior part of the HYPOTHALAMUS.

The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.

The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.

Artificially induced UTERINE CONTRACTION. Generally, LABOR, OBSTETRIC is induced with the intent to cause delivery of the fetus and termination of pregnancy.

The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.

The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.

Ventral part of the DIENCEPHALON extending from the region of the OPTIC CHIASM to the caudal border of the MAMMILLARY BODIES and forming the inferior and lateral walls of the THIRD VENTRICLE.

Degradation of CORPUS LUTEUM. In the absence of pregnancy and diminishing trophic hormones, the corpus luteum undergoes luteolysis which is characterized by the involution and cessation of its endocrine function.

The behavior patterns associated with or characteristic of a mother.

The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.

In animals, the social relationship established between a male and female for reproduction. It may include raising of young.

Any behavior caused by or affecting another individual, usually of the same species.

Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.

Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete.

Chemical substances which inhibit the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.

The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.

Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).

(9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics.

The final period of OBSTETRIC LABOR that is from the expulsion of the FETUS to the expulsion of the PLACENTA.

Failure of the UTERUS to contract with normal strength, duration, and intervals during childbirth (LABOR, OBSTETRIC). It is also called uterine atony.

Vasopressin stimulation of acetate incorporation into lipids in a dimethylbenz(a)anthracene-induced rat mammary tumor cell line. (1/1958)

In a preliminary report we described the effects of rat prolactin on the incorporation of [14C]acetate into lipids by a cell line from a dimethylbenz(a)anthracene-induced rat mammary tumor. The characteristics of the response to prolactin were very similar to those described for the normal rat mammary gland; namely, insulin was required for full expression of the response, maximal activity was not seen until 36 hr after the addition of the hormones, and growth hormone was able to elicit the same response. However, we were unable to detect binding of 125I-labeled prolactin to these cells, and furthermore, other more purified prolactin preparations were inactive. Upon further investigation we discovered that the activity resided in a low-molecular-weight fraction of the rat prolactin B-1 preparation and was probably either vasopressin or oxytocin or both. These data suggest the possibility that vasopressin may play a role in rodent mammary tumorigenesis. (+info)

Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. (2/1958)

Little is known regarding the effect of chronic changes in neuronal activity on the extent of collateral sprouting by identified CNS neurons. We have investigated the relationship between activity and sprouting in oxytocin (OT) and vasopressin (VP) neurons of the hypothalamic magnocellular neurosecretory system (MNS). Uninjured MNS neurons undergo a robust collateral-sprouting response that restores the axon population of the neural lobe (NL) after a lesion of the contralateral MNS (). Simultaneously, lesioned rats develop chronic urinary hyperosmolality indicative of heightened neurosecretory activity. We therefore tested the hypothesis that sprouting MNS neurons are hyperactive by measuring changes in cell and nuclear diameters, OT and VP mRNA pools, and axonal cytochrome oxidase activity (COX). Each of these measures was significantly elevated during the period of most rapid axonal growth between 1 and 4 weeks after the lesion, confirming that both OT and VP neurons are hyperactive while undergoing collateral sprouting. In a second study the hypothesis that chronic inhibition of neuronal activity would interfere with the sprouting response was tested. Chronic hyponatremia (CH) was induced 3 d before the hypothalamic lesion and sustained for 4 weeks to suppress neurosecretory activity. CH abolished the lesion-induced increases in OT and VP mRNA pools and virtually eliminated measurable COX activity in MNS terminals. Counts of the total number of axon profiles in the NL revealed that CH also prevented axonal sprouting from occurring. These results are consistent with the hypothesis that increased neuronal activity is required for denervation-induced collateral sprouting to occur in the MNS. (+info)

Production of prostaglandin f2alpha and its metabolite by endometrium and yolk sac placenta in late gestation in the tammar wallaby, Macropus Eugenii. (3/1958)

In this study, we investigated production of prostaglandin (PG) F2alpha and its metabolite, PGFM, by uterine tissues from tammar wallabies in late pregnancy. Endometrial explants were prepared from gravid and nongravid uteri of tammars between Day 18 of gestation (primitive streak) and Day 26.5 (term) and were incubated in Ham's F-10 medium supplemented with glutamine and antibiotics for 20 h. PGF2alpha and PGFM in the medium were assayed by specific, validated RIAs. Control tissues (leg muscle) did not produce detectable amounts of either PG. Both gravid and nongravid endometria secreted PGF2alpha, and production increased significantly in both gravid and nongravid uteri towards term. PGFM was produced in small amounts by both gravid and nongravid uteri, and the rate of production did not increase. Neither oxytocin nor dexamethasone stimulated PG production in vitro in any tissue at any stage. Thus, the surge in peripheral plasma PGFM levels seen at parturition may arise from increased uterine PG production, but further study is needed to define what triggers this release. (+info)

Down-regulation of oxytocin-induced cyclooxygenase-2 and prostaglandin F synthase expression by interferon-tau in bovine endometrial cells. (4/1958)

Oxytocin (OT) is responsible for the episodic release of luteolytic prostaglandin (PG) F2alpha from the uterus in ruminants. The attenuation of OT-stimulated uterine PGF2alpha secretion by interferon-tau (IFN-tau) is essential for prevention of luteolysis during pregnancy in cows. To better understand the mechanisms involved, the effect of recombinant bovine IFN-tau (rbIFN-tau) on OT-induced PG production and cyclooxygenase-2 (COX-2) and PGF synthase (PGFS) expression in cultured endometrial epithelial cells was investigated. Cells were obtained from cows at Days 1-3 of the estrous cycle and cultured to confluence in RPMI medium supplemented with 5% steroid-free fetal calf serum. The cells were then incubated in the presence or absence of either 100 ng/ml OT or OT+100 ng/ml rbIFN-tau for 3, 6, 12, and 24 h. OT significantly increased PGF2alpha and PGE2 secretion at all time points (p < 0.01), while rbIFN-tau inhibited the OT-induced PG production and reduced OT receptor binding in a time-dependent manner. OT increased the steady-state level of COX-2 mRNA, measured by Northern blot, which was maximal at 3 h (9-fold increase) and then decreased with time (p < 0.01). OT also caused an increase in COX-2 protein, which peaked at 12 h (11-fold increase), as measured by Western blot. Addition of rbIFN-tau suppressed the induction of COX-2 mRNA (89%, p < 0.01) and COX-2 protein (50%, p < 0.01) by OT. OT also increased PGFS mRNA, and this stimulation was attenuated by rbIFN-tau (p < 0.01). To ensure that the decrease in COX-2 was not solely due to down-regulation of the OT receptor, cells were stimulated with a phorbol ester (phorbol 12-myristate 13-acetate; PMA) in the presence and absence of rbIFN-tau. The results showed that rbIFN-tau also decreased PMA-stimulated PG production and COX-2 protein. It can be concluded that rbIFN-tau inhibition of OT-stimulated PG production is due to down-regulation of OT receptor, COX-2, and PGFS. (+info)

Oxytocin and vasopressin receptors in human and uterine myomas during menstrual cycle and early pregnancy. (5/1958)

The purpose of this study was to determine the specificity and concentration of oxytocin (OT) and arginine vasopressin (AVP) binding sites in non-pregnant (NP) human and rhesus monkey endometrium, myometrium and fibromyomas, and to determine the cellular localization of OT receptor (OTR). Besides [3H]AVP, [125I]LVA, a specific VP1 receptor subtype antagonist, was used to determine vasopressin receptor (VPR) concentrations. Samples were obtained from 42 pre-menopausal and three pregnant women (5, 13 and 35 weeks gestation), and several NP and pregnant monkeys. Specificity of binding was assessed in competition experiments with unlabelled agonists and antagonists of known pharmacological potency. Cellular localization of OTR was determined by immunohistochemistry. In NP human uterine tissues, [3H]AVP was bound with higher affinity and greater binding capacity than [3H]OT, whereas in pregnant women and in NP and pregnant rhesus monkeys, uterine OT binding capacity was greater. OT and AVP binding sites discriminated very poorly between OT and AVP; [125I]LVA binding sites were more selective than [3H]AVP. Their ligand specificity and binding kinetics indicated the presence of two distinct populations of binding sites for OT and AVP in primate uterus. Endometrium of NP women and monkeys had low OTR and VPR concentrations. Myometrial and endometrial OTR and VPR were down-regulated in midcycle and in early human pregnancy, they were up-regulated in the secretory phase and second half of pregnancy. Immunoreactive OTR in NP uterus was localized in patches of myometrial muscle cells and small numbers of endometrial epithelial cells. (+info)

Desensitization of oxytocin receptors in human myometrium. (6/1958)

In the present study, we investigated the possible mechanisms by which oxytocin might regulate oxytocin receptor (OTR) density. Exposure of cultured myometrial cells to oxytocin for a prolonged period caused desensitization: the steady-state level of oxytocin binding was 210 x 10(3) binding sites/cell, but this was time-dependently reduced to 20.1 x 10(3) sites/cell by exposing the cells to oxytocin for up to 20 h. In contrast, Western blotting data showed that the total amount of OTR protein was not affected by oxytocin treatment for up to 24 h. Flow cytometry experiments demonstrated that OTRs were not internalized during this treatment. However, RNase protection assays and Northern analysis showed that in cultured myometrial cells OTR mRNA was reduced by oxytocin treatment to reach a new low steady-state concentration. Analysis of this mRNA in myometrial biopsies from 17 patients undergoing emergency Caesarean section showed how it decreased with advancing labour. Samples obtained after 12 h of labour contained approximately 50 times less OTR mRNA than samples obtained from patients in labour for less than 12 h. We speculate that this decrease in OTR mRNA represents in-vivo OTR desensitization. (+info)

Uterine peristalsis during the follicular phase of the menstrual cycle: effects of oestrogen, antioestrogen and oxytocin. (7/1958)

Uterine peristalsis, directing sustained and rapid sperm transport from the external cervical os or the cervical crypts to the isthmic part of the tube ipsilateral to the dominant follicle, changes in direction and frequency during the menstrual cycle, with lowest activity during menstruation and highest activity at mid cycle. It was therefore suggested that uterine peristalsis is under the control of the dominant follicle with the additional involvement of oxytocin. To test this hypothesis, vaginal sonography of uterine peristalsis was performed in the early, mid and late proliferative phases, respectively, of cycles of women treated with oestradiol valerate and with human menopausal gonadotrophin following pituitary downregulation, with clomiphene citrate and with intravenous oxytocin, respectively. Administration of oestradiol valerate resulted in oestradiol serum concentrations comparable with the normal cycle with a simulation of the normal frequency of peristaltic contractions. Elevated oestradiol concentrations and bolus injections of oxytocin resulted in a significant increase in the frequency of peristaltic contractions in the early and mid follicular phases, respectively. Chlomiphene tended, though insignificantly so, to suppress the frequency of peristaltic waves in the presence of elevated oestradiol concentrations. In the late follicular phase of the cycle extremely elevated oestradiol concentrations as well as the injection of oxytocin resulted only in an insignificant further increase of peristaltic frequency. In the normal cycles, as well as during extremely elevated oestradiol concentrations and following oxytocin administration, the peristaltic contractions were always confined to the subendometrial layer of the muscular wall. The results and the review of literature indicate that uterine peristalsis during the follicular phase of the menstrual cycle is controlled by oestradiol released from the dominant follicle with the probable involvement of oxytocin, which is presumably stimulated together with its receptor within the endometrial-subendometrial unit and therefore acting in an autocrine/paracrine fashion. Since unphysiological stimulation with oestradiol and oxytocin did not significantly increase the frequency of uterine peristalsis in the late follicular phase of the cycle it is assumed that normal preovulatory frequency of uterine peristalsis is at a level which cannot be significantly surpassed due to phenomena of refractoriness of the system. (+info)

Sperm transport in the human female genital tract and its modulation by oxytocin as assessed by hysterosalpingoscintigraphy, hysterotonography, electrohysterography and Doppler sonography. (8/1958)

The transport function of the uterus and oviducts and its modulation by oxytocin has been examined using hysterosalpingoscintigraphy, recording of intrauterine pressure, electrohysterography and Doppler sonography of the Fallopian tubes. After application to the posterior vaginal fornix, a rapid (within minutes) uptake of the labelled particles into the uterus was observed during the follicular and during the luteal phase of the cycle in all patients. Transport into the oviducts, however, could only be demonstrated during the follicular phase. Transport was directed predominantly into the tube ipsilateral to the ovary bearing the dominant follicle; the contralateral oviduct appeared to be functionally closed. The proportion of patients exhibiting ipsilateral transport did increase concomitant with the increase of the diameter of the dominant follicle. That ipsilateral transport has biological significance is suggested by the observation that the pregnancy rate following spontaneous intercourse or insemination was significantly higher in those women in whom ipsilateral transport could be demonstrated than in those who failed to exhibit lateralization. Oxytocin administration was followed by a dramatic increase in the amount of material transported to the ipsilateral tube, as demonstrated by radionuclide imaging and by Doppler sonography following instillation of ultrasound contrast medium. Continuous recording of intrauterine pressure before and after oxytocin administration did show an increase in basal tonus and amplitude of contractions and a reversal of the pressure gradient from a fundo-cervical to a cervico-fundal direction. These actions of oxytocin were accompanied by an increase in amplitude of potentials recorded by electrohysterography. These data support the view that uterus and Fallopian tubes represent a functional unit that is acting as a peristaltic pump and that the increasing activity of this pump during the follicular phase of the menstrual cycle is reflected by an increased transport into the oviduct ipsilateral to the ovary bearing the dominant follicle. In addition, they strongly suggest a critical role of oxytocin in this process. Failure of this mechanism appears to be a cause of subfertility or infertility, as indicated by the low pregnancy rate following intrauterine insemination or normal intercourse in the presence of patent Fallopian tubes. It may be regarded as a new nosological entity for which we propose the term tubal transport disorder (TTD). Since pregnancy rate of such patients is normal when treated with in-vitro fertilization (IVF), hysterosalpingoscintigraphy seems to be useful for the choice of treatment modalities in patients with patent Fallopian tubes suffering from infertility. (+info)

... has a molecular mass of 1007 Da, and one international unit (IU) of oxytocin is the equivalent of 1.68 μg of pure ... Oxytocin is believed to have a significant role in social learning. There are indicators that oxytocin may help to decrease ... Secretion of oxytocin from the neurosecretory nerve endings is regulated by the electrical activity of the oxytocin cells in ... In male rats, oxytocin may induce erections. A burst of oxytocin is released during ejaculation in several species, including ...

https://en.wikipedia.org/wiki/Oxytocin

... orally bioavailable oxytocin antagonists. Peptide Carbetocin Demoxytocin Lipo-oxytocin-1 Merotocin Oxytocin Non-peptide TC OT ... The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of ... Wikimedia Commons has media related to Oxytocin receptors. Oxytocin+receptor at the US National Library of Medicine Medical ... Several selective ligands for the oxytocin receptor have recently been developed, but close similarity between the oxytocin and ...

https://en.wikipedia.org/wiki/Oxytocin_receptor

One IU of oxytocin is the equivalent of about 2 μg or mcg of pure peptide. Injection: Clinical doses of oxytocin are given by ... Intranasal oxytocin has a central duration of at least 2.25 hours and as long as 4 hours. Oral: Oxytocin is destroyed in the ... Oxytocin's milk ejection property was described by Ott and Scott in 1910 and by Schafer and Mackenzie in 1911. Oxytocin was the ... Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. As a ...

https://en.wikipedia.org/wiki/Oxytocin_(medication)

"Oxytocin" as an EDM song: The Ringer Source labling "Oxytocin" as an electronica song: ABC News Sources labling "Oxytocin" as ... "Oxytocin" as the 86th best song of 2021 according to the website's readers. "Oxytocin" was released as the fifth track on ... "Oxytocin" has been called the 20th best song by Billie Eilish by Far Out Magazine's Tyler Golsen, stating it is the "perfect ... "Oxytocin" received many comparitions to other artists' works. For The Line of Best Fit, Matthew Kent saw that the song is "club ...

https://en.wikipedia.org/wiki/Oxytocin_(song)

... (LOT-1) is a synthetic peptide and derivative of oxytocin that acts as an agonist of the oxytocin receptor. The ... After adjusting for molecular weight (LOT-1 is ~1.5x the weight of oxytocin), oxytocin and LOT-1 are equipotent. In addition, ... "Lipo-oxytocin-1, a Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-Lasting Effects on Anxiety-Related ... It has yet to be determined whether LOT-1 possesses improved blood-brain-barrier permeability relative to oxytocin. Carbetocin ...

https://en.wikipedia.org/wiki/Lipo-oxytocin-1

... Oxytocin (OT) has potential to be a treatment for Postpartum Depression (PPD)[1]. ... This method is often the preferred method[4]. Oxytocin (OT) is a neuropeptide that can be administered in this manner. IN ... A review of 38 randomized and controlled trials suggests that short-term use of intranasal oxytocin appears to have few side- ... Short-term use of intranasal oxytocin (OT) appears to be equally safe in vulnerable individuals as well as those deemed healthy ...

https://en.wikipedia.org/wiki/Oxytocin_treatment_for_postpartum_depression

In 2019, a large review of the effects of oxytocin found that the oxytocin level in fathers that engage in SSC is increased as ... Oxytocin is further released during labour when the fetus stimulates the cervix and vagina, and it is believed that it plays a ... Oxytocin is the most common method used to increase the rate of vaginal delivery. The World Health Organization recommends its ... The act of nursing a child also causes a release of oxytocin to help the baby get milk more easily from the nipple. Station ...

https://en.wikipedia.org/wiki/Childbirth

"Oxytocin, Carbetocin". IOCB Prague. Retrieved 2022-08-05. Prague, IOCB. "Guaiazulene". IOCB Prague. Retrieved 2022-08-05. ... the development of first method for industrial production of human neurohypophysial hormone oxytocin by Josef Rudinger, ...

https://en.wikipedia.org/wiki/Institute_of_Organic_Chemistry_and_Biochemistry

... oxytocin; VSP: vasopressin; NP: Neuropeptides; KOR, MOR, DOR: kappa-, mu- and delta-opioid receptors correspondingly. The FET ...

https://en.wikipedia.org/wiki/Functional_Ensemble_of_Temperament

Oxytocin and coitus. Sexual and Relationship Therapy (1988);3:29-36 Carter CS. Oxytocin and sexual behavior. Neuroscience & ... Oxytocin has been suggested as critical to the thoughts and behaviors required to maintain close relationships.[verification ... Prolactin and oxytocin are responsible for inducing milk production in women. Follicle-stimulating hormone (FSH) is responsible ... Sexual intimacy and orgasms increase levels of oxytocin, which helps people bond and build trust. A long-term study of 3,500 ...

https://en.wikipedia.org/wiki/Human_sexuality

Oxytocin and coitus. Sexual and Relationship Therapy (1988);3:29-36 Carter, CS. (1992). "Oxytocin and sexual behavior". ... Lee HJ, Macbeth AH, Pagani JH, Young WS (June 2009). "Oxytocin: the great facilitator of life". Prog. Neurobiol. 88 (2): 127-51 ... increases levels of the hormone oxytocin, also known as "the love hormone", which helps people bond and build trust. Sexual ...

https://en.wikipedia.org/wiki/Death_during_consensual_sex

The hormones oxytocin and vasopressin are implicated in regulating both male and female sexual motivation. Oxytocin is released ... Based on the pleasure model of sexual motivation, the increased sexual pleasure that occurs following oxytocin release may ... Emotional closeness can be an especially strong predictor of sexual motivation in females and insufficient oxytocin release may ... Keverne E. B.; Curley J. P. (2004). "Vasopressin, oxytocin and social behaviour". Neurobiology. 14 (6): 777-783. doi:10.1016/j. ...

https://en.wikipedia.org/wiki/Effects_of_hormones_on_sexual_motivation

"Oxytocin intranasal - Vyera Pharmaceuticals". AdisInsight. Retrieved 24 September 2017. Mullin, Emily (February 27, 2015). " ... Syntocinon, short for 'synthetic oxytocin', was first introduced by the Swiss pharmaceutical company Sandoz in 1956. The ... "Retrophin Signs U.S. License Agreement for Syntocinon™ Nasal Spray (Oxytocin)". Business Wire. December 12, 2013. Retrieved 19 ... This product, also called TUR-001, is Turing Pharmaceuticals' oxytocin nasal solution. ...

https://en.wikipedia.org/wiki/Vyera_Pharmaceuticals

"Oxytocin and social norms reduce xenophobia". University of Bonn. 12 August 2017. Retrieved 5 May 2019. "Raus aus der ... "Oxytocin and social norms reduce xenophobia". University of Bonn. 12 August 2017. Retrieved 5 January 2019. Michelle Castillo ( ... Scheele, D. (2012). "Oxytocin Modulates Social Distance between Males and Females". The Journal of Neuroscience. 32 (46): 16074 ... The same year, Hurlemann published research showing that oxytocin combined with a prominent social norm, could lead to ...

https://en.wikipedia.org/wiki/Rene_Hurlemann

... is a non-peptide partial agonist of the oxytocin and vasopressin V2 receptors (Ki = 147 nM and >1000 nM, respectively ... "Non-peptide oxytocin agonists". Bioorganic & Medicinal Chemistry Letters. 14 (17): 4585-4589. doi:10.1016/j.bmcl.2004.04.107. ... Oxytocin receptor agonists, Vasopressin receptor agonists, Vasopressin receptor antagonists, Thioamides, All stub articles, ...

https://en.wikipedia.org/wiki/TC_OT_39

I.D. Neumann, R.K. Liedtke, M. Ludwig, R. Langraf: Intranasally applied Oxytocin: Brain uptake and effects on neuronal ... Annual Meeting 2000, Melbourne R. K. Liedtke, R. Landgraf, I. D. Neumann, Intranasally applied Oxytocin: A novel route of ... Antidepressive effect of oxytocin. This has been predicted with a new biocybernetics model (1998/99), hereafter these effects ...

https://en.wikipedia.org/wiki/Rainer_Liedtke

Neurophysins are binding proteins, of which there are two types: neurophysin I and neurophysin II, which bind to oxytocin and ... Antidiuretic hormone (ADH) and oxytocin are both stored in Herring bodies, but are not stored simultaneously in the same ... Fibers from supraoptic nuclei are concerned with ADH secretion; paraventricular nuclei with oxytocin. This anatomical structure ...

https://en.wikipedia.org/wiki/Herring_bodies

The hormone oxytocin has been identified as inducing uterine contractions, and labour in general. Oxytocin is produced by the ... stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the ... In either form, oxytocin stimulates uterine contractions to accelerate the process of childbirth. Production and secretion of ... du Vigneaud V, Ressler C, Swan JM, Roberts CW, Katsoyannis PG (June 1954). "The synthesis of oxytocin". J. Am. Chem. Soc. 76 ( ...

https://en.wikipedia.org/wiki/Uterine_contraction

Greg Miller (2010), The prickly side of oxytocin, Science, 328, 1343 De Dreu, C.K.W., Greer, L.L., Van Kleef, G.A., Shalvi, S ... Using behavioral game theory and neuroscience methods, he showed how the hypothalamic neuropeptide oxytocin modelates self- ... "The neuropeptide oxytocin regulates parochial altruism in intergroup conflict among humans." Science, 328, 1408 - 1411. Prof. ... Handgraaf, M.J.J. (2011). Oxytocin promotes human ethnocentrism. Proceedings of the National Academy of Sciences USA, 108, 1262 ...

https://en.wikipedia.org/wiki/Carsten_de_Dreu

Oxytocin is associated with behaviors involving contact with the child. Increases in oxytocin following high contact ... Oxytocin has been shown to correlate with many aspects of paternal care, but its mechanisms and the systems involved are not ... Oxytocin's interactions with other hormones is thought to be responsible for creating variability in parent behaviors such as ... An increase in levels of oxytocin, glucocorticoids, estrogen and prolactin occur in the paternal brain. These hormonal changes ...

https://en.wikipedia.org/wiki/Paternal_brain

The peptide hormones oxytocin and vasopressin were isolated and their total syntheses first reported in 1954. It is not ... Vincent du Vigneaud was awarded the 1955 Nobel Prize in Chemistry for the total synthesis of the natural polypeptide oxytocin ... du Vigneaud V, Ressler C, Swan JM, Roberts CW, Katsoyannis PG (1954). "The Synthesis of Oxytocin". Journal of the American ...

https://en.wikipedia.org/wiki/Total_synthesis

"Trust, morality -- and oxytocin?". Anderson C, Kraus MW, Galinsky AD, Keltner D (July 2012). "The local-ladder effect: social ... Sasaki JY, Kim HS, Xu J (2011-11-01). "Religion and Well-being The Moderating Role of Culture and the Oxytocin Receptor (OXTR) ... Neuroeconomist Paul Zak studies morality, oxytocin, and trust, among other variables. Based on research findings, Zak ...

https://en.wikipedia.org/wiki/Well-being_contributing_factors

He also carried out a series of structure-activity relationships for oxytocin and vasopressin, perhaps the first of their type ... Even before his Nobel-Prize-winning work on elucidating and synthesizing oxytocin and vasopressin via manipulating the AVP gene ... Du Vigneaud, V. (1956). "Trail of sulfur research: from insulin to oxytocin". Science. 123 (3205): 967-974. Bibcode:1956Sci... ... a reference to his work on the peptide hormone oxytocin. Vincent du Vigneaud was born in Chicago in 1901, the son of French ...

https://en.wikipedia.org/wiki/Vincent_du_Vigneaud

Algoe, Sara B.; Kurtz, Laura E.; Grewen, Karen (2017-10-02). "Oxytocin and Social Bonds: The Role of Oxytocin in Perceptions of ... Oxytocin has also been found to play many roles in the bonding between mother and child. In addition to pair-bonding and ... Thus oxytocin may play a flexible role in relationship maintenance, supporting both the feelings that bring us closer and the ... In mammals, oxytocin has been found to be released during childbirth, breastfeeding, sexual stimulation, bonding, and in some ...

https://en.wikipedia.org/wiki/Social_connection

"Chemical trust: oxytocin oxymoron?" Am. J. Bioethics 5 (2005): 1. Henry, Rick; Tyler, Anthony O.; Coyne-DeGhett, Stephanie; ...

https://en.wikipedia.org/wiki/Darby_Penney

This condition can also be treated with drugs that increase dopamine, such as oxytocin, along with other drugs. In general, it ... IsHak WW, Berman DS, Peters A (April 2008). "Male anorgasmia treated with oxytocin". The Journal of Sexual Medicine. 5 (4): ... Other drugs which may be helpful in the treatment of this condition include dopamine agonists, oxytocin, phosphodiesterase type ...

https://en.wikipedia.org/wiki/Sexual_anhedonia

Serotonin and oxytocin levels are minimised, and the general immune system shows a level of suppression. Such a pattern is ... Kosfeld, M.; Heinrichs, M; Zak, P.J.; Fischbacher, U.; Fehr, E. (2005). "Oxytocin increases trust in humans". Nature. 435 (7042 ...

https://en.wikipedia.org/wiki/Homo_economicus

The role of oxytocin in autism and schizophrenia has also been researched, and some findings and characterizations of the ... Oxytocin appears to have treatment potential in both autism and schizophrenia, likely including schizotypal personality ... Shilling PD, Feifel D (5 June 2017). "Potential of Oxytocin in the Treatment of Schizophrenia". CNS Drugs. 30 (3): 193-208. doi ... Perez-Rodriguez MM, Derish NE, New AS (2014). "The Use of Oxytocin in Personality Disorders: Rationale and Current Status". ...

https://en.wikipedia.org/wiki/Imprinted_brain_hypothesis

AVP2 and oxytocin receptors. AVPR1B maps to chromosome region 1q32 and is a member of the vasopressin/oxytocin family subfamily ... "Vasopressin and Oxytocin Receptors: V1B". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and ... the first V1b-selective agonist for rat vasopressin/oxytocin receptors". Endocrinology. 148 (9): 4136-46. doi:10.1210/en.2006- ...

https://en.wikipedia.org/wiki/Vasopressin_receptor_1B

Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E (June 2005). "Oxytocin increases trust in humans". Nature. 435 (7042): ...

https://en.wikipedia.org/wiki/List_of_human_hormones

Oxytocin is also released when were physically intimate. Its tied to making us more trusting, more generous, and friendlier, ... Sometimes called the love hormone, oxytocin plays a role in forming social bonds and trusting other people. Its the hormone ... Studies are investigating if oxytocin can be beneficial in treating some conditions. The hormone is a protein and cannot simply ... Biochemically, you cant live on the 3-to-4-minute oxytocin boost that comes from a single act. ...

https://www.cedars-sinai.org/blog/science-of-kindness.html

Oxytocin and social norms reduce xenophobia Oxytocin and social norms reduce xenophobia Researchers from the University ... In such a prosocial context, oxytocin could increase trust and minimize anxiety - experience shows that the oxytocin level in ... Oxytocin in combination with social norms decreases xenophobia. How can people who tend to have a xenophobic attitude be ... Then half of the group received the bonding hormone oxytocin via a nasal spray, while the other half of the group received a ...

https://www.uni-bonn.de/en/university/press-and-communications/press-service/archive-press-releases/2017/188-2017

Oxytocin Injection: learn about side effects, dosage, special precautions, and more on MedlinePlus ... Before receiving oxytocin injection,. *tell your doctor and pharmacist if you are allergic to oxytocin, any other medications, ... Oxytocin injection is used to begin or improve contractions during labor. Oxytocin also is used to reduce bleeding after ... Oxytocin should not be used to induce labor (to help start the birth process in a pregnant woman), unless there is a valid ...

https://medlineplus.gov/druginfo/meds/a682685.html

Intranasal oxytocin may enhance fear extinction therapy for patients with anxiety disorders, early research suggests. ... T]he results of our study indicate that a 24 IU single-dose administration of OXT [oxytocin] increases fear extinction-related ... 7, 2014) Intranasal oxytocin (multiple brands) may enhance fear extinction therapy for patients with anxiety disorders, ... "This study should certainly stimulate further research into the possibility of this role for oxytocin. But at this point, we ...

https://www.medscape.com/viewarticle/834585

... buccal oxytocin and buccal desamino-oxytocin / A. N. J. A. de Groot ... [‎et al.]‎ ... WHO/UNICEF/UNFPA joint statement: appropriate storage and management of oxytocin, a key commodity for maternal health ... WHO recommendation on routes of oxytocin administration for the prevention of postpartum haemorrhage after vaginal birth ... WHO recommendation on umbilical vein injection of oxytocin for the treatment of retained placenta ...

https://apps.who.int/iris/browse?authority=Oxytocin&type=mesh

... Nature. 2005 Jun 2;435(7042):673-6. doi: 10.1038/nature03701. ... We also show that the effect of oxytocin on trust is not due to a general increase in the readiness to bear risks. On the ... Here we show that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and ... These results concur with animal research suggesting an essential role for oxytocin as a biological basis of prosocial approach ...

https://pubmed.ncbi.nlm.nih.gov/15931222/

https://extranet.who.int/iris/restricted/browse?authority=Oxytocin&type=mesh

Sales and business experts have always talked about the power of a handshake to make a good first impression and start building a relationship. Researchers at the University of Iowa showed that to be the case when they found that job ...

https://www.neurosciencemarketing.com/blog/articles/tag/oxytocin

Side effects of Oxytocin (detailed). Similar questions. What are the nursing considerations when administering oxytocin?. ... Oxytocin - My wife suffered after childbirth from severe vomiting, how can we avoid this next time?. Updated 26 April 2012 1 ... Finally, oxytocin in seminal fluid is discussed and its possible role in respect to the fate of the semen following ejaculation ... What will happen if we give oxytocin to males?. Question posted by lokesh N.RAM on 17 March 2012 ...

https://www.drugs.com/answers/happen-give-oxytocin-males-533449.html

We found that oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice (OxtrPBN neurons) are key ... The authors show that oxytocin-receptor-expressing neurons in the parabrachial nucleus are key regulators of fluid homeostasis ... OxtrPBN neurons were directly innervated by oxytocin neurons in the paraventricular hypothalamus (OxtPVH neurons), which ... The PVH also contains oxytocin-expressing neurons that project within the CNS1. The oxytocin receptor (Oxtr) is expressed in ...

https://www.nature.com/articles/s41593-017-0014-z?error=cookies_not_supported

p,American neuroeconomist Paul Zak claims that the brain chemical oxytocin is responsible for trust and empathy. ,strong,Mark ... In addition, oxytocin has been shown to facilitate nurturing behaviour in mice and rats: when oxytocin was blocked, the rodents ... He named the extract oxytocin, from the Greek for "quick" and "birth". Within two years, doctors were using oxytocin to bring ... and then tested their blood for oxytocin. He wondered if the human subjects would show a similar spike in oxytocin? ...

https://www.theguardian.com/science/2011/aug/21/oxytocin-zak-neuroscience-trust-hormone

High levels of oxytocin cause people to work harder to help the group achieve its goals. We know it is oxytocin causing ... OXYTOCIN and Purpose exemplars In order to make this scalable, I created a survey (that you can try for yourself) that measures ... Oxytocin at work. Of course, I did not start a long research program without some hypotheses. My experiments in the early 2000s ... How Oxytocin Can Make Your Job More Meaningful. Does your job suck? Neuroscience research suggests it might be missing two key ...

https://greatergood.berkeley.edu/article/item/how_oxytocin_can_make_your_job_more_meaningful

... oxytocin could improve some of the social deficits characteristic of people with autism. ... Oxytocin and development:. Doctors in North America and elsewhere often use a synthetic form of oxytocin, called pitocin, to ... The oxytocin receptor - which directs changes in the cell in response to oxytocin - shows considerable variation both within ... Treatment with oxytocin is associated with an increase in methylation, a chemical modification of the oxytocin receptor gene ( ...

https://www.sfari.org/2011/05/19/workshop-report-oxytocin-and-autism/

Scientists find that the love hormone oxytocin can boost heart cells ability to regenerate, literally helping mend a broken ... Share "Love hormone" oxytocin literally heals a broken heart on Twitter Share "Love hormone" oxytocin literally heals a broken ... "Love hormone" oxytocin literally heals a broken heart. Oxytocin can boost heart cells ability to regenerate. ... "Next, we need to look at oxytocin in humans after cardiac injury. Oxytocin itself is short-lived in the circulation, so its ...

https://bigthink.com/health/love-hormone-oxytocin-heals-broken-heart/

This study was conducted to investigate the preventive effect of oxytocin (OT) on cisplatin-induced neurotoxicity in rats. ... We suggest that oxytocin may have beneficial effects against cisplatin-induced neurotoxicity. ... The effects of oxytocin on plasma TNF-α levels in all groups. Results were presented as mean ± SEM. , different from normal and ... The effects of oxytocin on plasma MDA levels in all groups. Results were presented as mean ± SEM. , different from normal and ...

https://www.hindawi.com/journals/bmri/2015/167235/

... (PDF, 63 kB, 15.05.2018) ... Swissmedic informiert über eine befristete Bewilligung zum Vertrieb von 33450 Oxytocin Stricker ad us. vet., Injektionslösung ... www.swissmedic.ch/content/swissmedic/de/home/tierarzneimittel/market-surveillance/out-of-stock-tam/out-of-stock-oxytocin- ...

https://www.swissmedic.ch/swissmedic/de/home/tierarzneimittel/market-surveillance/out-of-stock-tam/out-of-stock-oxytocin-stricker-ad-us-vet-injektionsloesung.html

... oxytocin, helps people become more comfortable and sociable. Zak spent 10 years conducting extensive studies on oxytocin, ... "Touch releases oxytocin," he said. "So Im going to suggest that everyone have at least eight hugs a day." ... This portion of the population has inadequate oxytocin receptors. At the end of the lecture he was asked if these groups can be ... Author Paul Zak talked to a crowd of more than 100 people about his extensive studies on how the chemical, oxytocin, helps ...

https://sundial.csun.edu/60260/news/dr-love-lectures-on-oxytocin-at-csun/?print=true

Human babies are born helpless, needing to be entirely cared for and protected. Luckily, they are born with all the necessary tools and "instructions" to attain such care for themselves, and to become a loved and loving part of their family and society.. ...

https://babyreference.com/tag/oxytocin/

Until oxytocin is properly studied in PWS, it could be dangerous or ineffective to give your loved one oxytocin. As the father ... One important consideration is what form of oxytocin to use. Not all oxytocin is the same. Each form of the drug might be made ... We are aware that oxytocin is available today through the internet or compound pharmacies. Despite the potential of oxytocin, ... It has been nearly one year since we learned of the initial potential of oxytocin and PWSA (USA) began raising funds for the ...

https://www.pwsausa.org/update-oxytocin-phase-2-trial/

allergy to oxytocin or lidocaine Yes for allergy to oxytocin or lidocaine exclusion criteria 1 ... and this effect is blocked by an oxytocin receptor antagonist (5). Intrathecal injection of oxytocin in normal rats reduces ... and produces analgesia by spinal release of oxytocin, since intrathecal injection of an oxytocin receptor antagonist worsens ... Oxytocin containing cells in the dorsal parvocellular division of the paraventricular nucleus (PVN) project to the spinal cord ...

https://www.centerwatch.com/clinical-trials/listings/176388/efficacy-of-spinal-oxytocin-in-healthy-volunteers/

Oxytocin deficiency has now been found in every known psychological, emotional disorder-AHHD, Autism, Anxiety, Depression, ... Oxytocin, The Essential Hormone for Happiness, Health and Longevity / Menopausal Bliss January 23, 2013. /in Lifestyle and ... Oxytocin-The Essential Hormone for Happiness, Health and Longevity. C. Norman Shealy, M.D., Ph.D. ... Oxytocin deficiency has now been found in every known psychological, emotional disorder-AHHD, Autism, Anxiety, Depression, ...

https://normshealy.com/oxytocin-the-essential-hormone-for-happiness-health-and-longevity-menopausal-bliss/

Oxytocin is a Stem Cell Signal. Oxytocin levels decline with age, and this summer, there was an article in Naturesuggesting ... Trust hormone oxytocin helps old muscle work like new, study finds. *. Muscles Love Oxytocin: So-Called "Hug Hormone" ... A recent study connects loss of oxytocin with frailty and loss of muscle mass in old age. Could it be that oxytocin is the ... Other roles of oxytocin. Oxytocin is known for several other functions. It suppresses our fear and protectiveness. Delivered ...

https://hplusmagazine.com/2014/08/19/love-death-oxytocin/

The hormone oxytocin - known as the love drug or cuddle chemical - plays an important role in pair-bonding, child-rearing ... It turns out, however, that oxytocin is not the common denominator between the two drugs - MDMA may increase oxytocin, while ... But, interestingly, increasing oxytocin may reduce desire for meth. McGregor found that giving rats oxytocin made them lose ... "We published a paper last year showing that baclofen strongly activated oxytocin in the rat brain," says McGregor. And oxytocin ...

https://healthland.time.com/2010/12/21/what-does-meth-research-have-to-do-with-addiction-and-autism-treatments-its-oxytocin/

To fulfill its many roles, oxytocin has to dock at a protein called the oxytocin receptor, encoded by a gene called OXTR. ... and asked them to sniff either an oxytocin nasal spray or another spray with the same ingredients minus oxytocin - a placebo. A ... Oxytocin is a versatile actor, whose resume includes all sorts of jobs in sex, reproduction, social behaviour and emotions. It ... The Dark Side of Oxytocin, Much More Than Just a "Love Hormone". In fact, it can be the opposite.. Not Exactly Rocket ScienceBy ...

https://www.discovermagazine.com/the-sciences/the-dark-side-of-oxytocin-much-more-than-just-a-love-hormone

Continuous oxytocin versus intermittent oxytocin for induction of labor: a randomized study. J Matern Fetal Neonatal Med2020;33 ... defined as more than five contractions in 10 minutes in response to oxytocin.567 Different approaches to oxytocin ... Oxytocin discontinuation after the active phase of induced labor: A systematic review. Women Birth2019;32:112-8. doi:10.1016/j. ... Oxytocin discontinuation during active labor in women who undergo labor induction. Am J Obstet Gynecol2012;207:471.e1-8. doi: ...

https://www.bmj.com/content/373/bmj.n716

One of its key players is oxytocin hormone. The neuropeptide, oxytocin (OT), has well-established roles during parturition and ... Several studies suggest that oxytocin is implicated in the central control of responses to stress through modulation of ... 36. Patisaul, H.B., Scordalakes, E.M., Young, L.J. and Rissman, E.F. (2003) Oxytocin, But Not Oxytocin Receptor, Is Regulated ... One of its key players is oxytocin hormone. The neuropeptide, oxytocin (OT), has well-established roles during parturition and ...

https://file.scirp.org/Html/3-1980273_83228.htm

... has shown that therapy helps men read emotions more than dosing with oxytocin, which is released naturally and plays an ... Love Isnt The Drug: Oxytocin Supplements Unlikely To Mend Marriages. 4 months, 2 weeks ago ... She said: "Our study serves as an important reminder that oxytocin may not always be the most effective tool when trying to ... Daughters, from the Department of Psychology, says more research is now needed to test oxytocin with women and on those who ...

https://worldhealth.net/news/love-isnt-drug-oxytocin-supplements-unlikely-mend-marriages/

... determine changes in the salivary oxytocin (OT) level during breast stimulation for promoting the spontaneous onset of labor in ...

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192757

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of holistic, natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional ...

https://alternativemedicine.com/tag/oxytocin/

What are oxytocin assays measuring? Epitope mapping, metabolites, and comparisons of wildtype & knockout mouse urine. View ... Oxytocin has become a popular analyte in behavioral endocrinology in recent years, due in part to its roles in social behavior ... Using samples from oxytocin knockout (KO) and wildtype (WT) mice, we find evidence of considerable interference in unextracted ... What are oxytocin assays measuring? Epitope mapping, metabolites, and comparisons of wildtype & knockout mouse urine ...

https://www.biorxiv.org/content/10.1101/2022.03.03.482682v1

Then half of the group received the bonding hormone oxytocin via a nasal spray, while the other half of the group received a placebo before they were exposed to the donation task established in the first experiment: again the participants decided how much of their 50 euros they wanted to donate to locals or refugees. (uni-bonn.de)
A randomized controlled trial of 62 healthy male participants showed that those who received intranasal oxytocin soon after undergoing a fear conditioning task had increased inhibition, or a tamping down, of amygdalar responses during extinction therapy compared with matched peers who received placebo. (medscape.com)
The current study included 62 healthy, left-handed male volunteers (mean age, 24.6 years) who were randomly assigned to receive either a 24 IU intranasal dose of synthetic oxytocin or matching placebo. (medscape.com)
Dr Acheson, who was not involved with this research, published a study last year in Psychopharmacology that examined 44 healthy participants who underwent a conditioned fear acquisition procedure, after which one half were randomly assigned to receive intranasal oxytocin and the other half, placebo. (medscape.com)
She recruited 31 men* and asked them to sniff either an oxytocin nasal spray or another spray with the same ingredients minus oxytocin - a placebo. (discovermagazine.com)
A few weeks later, the sprays were swapped so that the men who took oxytocin now took the placebo, and vice versa. (discovermagazine.com)
Those who felt more anxious about their relationships took a dimmer view of their mother's parenting styles when they sniffed oxytocin, compared to the placebo. (discovermagazine.com)
Some were given intranasal oxytocin, others a placebo and then took some took part in either an accredited emotional training program - known as the Cardiff Emotion Recognition Training program - or a mock training program. (worldhealth.net)
The same men also visited the clinic in a monthly interval to receive oxytocin and then later to receive a placebo. (primal-page.com)
This review considers the efficacy and safety of oxytocin prophylaxis in the third stage of labour compared with no uterotonics, a placebo, ergot alkaloids, and in combination with ergometrine compared with ergot alkaloids. (cochrane.org)
Our results showed that compared to no uterotonics or placebo, oxytocin may reduce the risk of blood loss (quality of evidence: low) and the need for additional uterotonics (quality of evidence: moderate). (cochrane.org)
More placebo-controlled, randomised, double-blinded trials are needed to improve the quality of data used to compare oxytocin versus ergot alkaloids. (cochrane.org)
The dogs were administered either intranasal oxytocin or placebo and were subjected to a series of behavioral tests. (nationalcanineresearchcouncil.com)
We also administered exogenous oxytocin intravenously and intranasally in a triple dummy, within-subject, placebo-controlled design and compared baseline levels and the effects of routes of administration. (elifesciences.org)

We suggest that oxytocin may have beneficial effects against cisplatin-induced neurotoxicity. (hindawi.com)
Several studies suggest that oxytocin is implicated in the central control of responses to stress through modulation of corticotrophin releasing hormone (CRH). (scirp.org)
These various functions suggest that oxytocin may promote health by reducing stress and increasing calm/relaxed states, resulting in improved quality of life and well-being. (mindandlife.org)
Both studies, which were presented at the 2016 meeting of the Society of Biological Psychiatry, suggest that oxytocin is a promising potential treatment for drug addictions. (bipolarnews.org)

Paul Zak believes oxytocin could help give people more empathy. (theguardian.com)
The key, he says, is to kickstart a brain circuit called HOME (human oxytocin-mediated empathy). (theguardian.com)
The enhanced empathy enabled by oxytocin allows humans to quickly form teams and work together effectively. (berkeley.edu)
A number of studies have suggested that the so-called 'love hormone' oxytocin enhances trust, emotion recognition and even empathy in the typical population. (sfari.org)
Zak said he suggested the man seek therapy because there was nothing he could do and told the audience that empathy is part of the effects of oxytocin. (csun.edu)
In recent studies in humans, oxytocin has been shown to be associated with increases in prosocial behaviors such as trust, altruism, generosity, cooperation and empathy. (mindandlife.org)
Although oxytocin hormone is involved in social behaviors and empathy, it has not been studied in sled dogs. (conicet.gov.ar)
Oxytocin is also associated with trust, empathy, and relationship-building. (littlethaifoodataustin.com)

We also show that the effect of oxytocin on trust is not due to a general increase in the readiness to bear risks. (nih.gov)
This study was conducted to investigate the preventive effect of oxytocin (OT) on cisplatin-induced neurotoxicity in rats. (hindawi.com)
The effect of oxytocin compared with ergot alkaloids is uncertain with regards to blood loss (quality of evidence: very low), need for additional uterotonics (quality of evidence: very low), and need for blood transfusion (quality of evidence: very low), but may increase the risk of a third stage greater than 30 minutes (quality of evidence: moderate). (cochrane.org)
The effect of oxytocin compared to ergot alkaloids is uncertain with regards to blood loss, need for additional uterotonics, and blood transfusion. (cochrane.org)

We found that oxytocin-receptor-expressing neurons in the parabrachial nucleus of mice (Oxtr PBN neurons) are key regulators of fluid satiation. (nature.com)
They found that oxytocin had the most potent effect: It increased the EpiPCs' ability to proliferate three-fold compared to untreated cells, a much stronger impact than other molecules previously shown to stimulate EpiPC production in mice. (bigthink.com)
Jennifer Bartz from the Mount Sinai School of Medicine has found that oxytocin can have completely opposite effects on the way people behave, depending on how they view their relationships to other people. (discovermagazine.com)
Researchers have found that oxytocin, commonly known as the "love hormone" may not be crucial for the social behaviors it's known for. (stanford.edu)

Through the combined administration of oxytocin with a social norm, the donations for refugees in those skeptical towards migrants nearly reached half of the sums donated by the group, which showed a positive attitude towards refugees. (uni-bonn.de)
Here we show that intranasal administration of oxytocin, a neuropeptide that plays a key role in social attachment and affiliation in non-human mammals, causes a substantial increase in trust among humans, thereby greatly increasing the benefits from social interactions. (nih.gov)
Perhaps the administration of oxytocin could be used as an aid in the unrepressing of traumas in the deep abreactive psychotherapies! (primal-page.com)

We conducted a study to look at the effects of two mind-body therapies on changes in salivary oxytocin levels in a cancer survivor population with self-reported sleep disturbance. (mindandlife.org)

Interestingly, having more receptors in the reward area of the brain enhances the social functions of oxytocin, such as pair-bonding. (sfari.org)
Meadow voles have fewer oxytocin receptors in the nucleus accumbens, a brain region that mediates reward, compared with prairie voles. (sfari.org)
This portion of the population has inadequate oxytocin receptors. (csun.edu)

Oxytocin is conserved in both structure and function across diverse species, suggesting that many of the findings in animal models are likely to be applicable to humans. (sfari.org)
These results show that it is likely that the stimulation by oxytocin of EpiPC production is evolutionary [sic] conserved in humans to a significant extent. (bigthink.com)
Zak said his studies in Papua New Guinea provided evidence that oxytocin is a chemical that affects humans the same way universally. (csun.edu)
Purpose: There is a strong experimental basis to support the study of oxytocin by the spinal route for analgesia in humans. (centerwatch.com)
Rationale: We anticipate that oxytocin will be effective after spinal injection in humans against chemical induced hypersensitivity states. (centerwatch.com)
Administration of MDMA increases plasma oxytocin levels in humans," says Gillinder Bedi, Columbia University assistant professor of clinical psychology and lead author of new research on the effects of MDMA and methamphetamine, which I reported previously here . (time.com)
Here we show that oxytocin, a neuropeptide also known as the love hormone, is capable of activating heart repair mechanisms in injured hearts in zebrafish and human cell cultures, opening the door to potential new therapies for heart regeneration in humans," said Dr Aitor Aguirre, an assistant professor at the Department of Biomedical Engineering of Michigan State University, and the study's senior author. (neurosciencenews.com)
Oxytocin has similar effects for humans as for mice, however, it is not yet clear if the hormone influences the human version of this mouse interaction, or if it works through a similar population of interneurons. (nutritionreview.org)
Our findings question the use of single measurements of baseline oxytocin concentrations in saliva and plasma as valid trait markers of the physiology of the oxytocin system in humans. (elifesciences.org)

Sometimes called 'the love hormone,' oxytocin plays a role in forming social bonds and trusting other people. (cedars-sinai.org)
Researchers at University Hospital Bonn have shown in a new study that the bonding hormone oxytocin together with social norms significantly increases the willingness to donate money to refugees in need, even in people who tend to have a skeptical attitude towards migrants. (uni-bonn.de)
In the male mammal, the small peptide hormone oxytocin is produced in similar quantities within the hypothalamo-pituitary magnocellular system as in the female, yet for the male little is known about the physiology associated with this hormone. (drugs.com)
The "love hormone" oxytocin creates social bonds and generates the pleasurable feelings associated with art , exercise, and sex . (bigthink.com)
The hormone oxytocin - known as the "love drug" or "cuddle chemical" - plays an important role in pair-bonding, child-rearing and social behavior. (time.com)
Often called "the love hormone," oxytocin is a powerful neurotransmitter that regulates social interaction, pair bonding, milk release, uterine contractions and sexual reproduction. (salimetrics.com)
T he headlines of a recent article in MedlinePlus announced that recent evidence has shown that the 'Love Hormone', oxytocin, may boost our 'memories of mama' -- either good ones or bad ones. (primal-page.com)
The 'love' hormone oxytocin is released in the brain during sexual activity and also when a baby suckles. (thenakedscientists.com)
Does 'Love Hormone' Oxytocin Play a Role in Pair Bonding? (mental-health.news)
The 'love hormone' oxytocin has long been thought key to behaviours including pairing up with a partner and nurturing offspring, but a new study in prairie voles is raising doubts. (panatimes.com)

Salimetrics launches validated and optimized salivary oxytocin assay for researchers sending samples for testing to the Salimetrics SalivaLab. (salimetrics.com)
Today, Salimetrics' strong bond with the salivary bioscience community grows even stronger with the launch of a high sensitivity salivary oxytocin assay, now available through the Salimetrics SalivaLab testing service. (salimetrics.com)
We're proud to make reliable testing of salivary oxytocin easy and readily accessible to investigators for the first-time. (salimetrics.com)
Concurrent research provides a robust background that highlights salivary oxytocin as an important biomarker for researching emotional, cognitive, and other behavioral fields of interest. (salimetrics.com)
Investigators can visit the Salimetrics Website to learn more about salivary oxytocin, now available through the Salimetrics SalivaLab, or to submit a request for a quote . (salimetrics.com)
The availability of oxytocin testing now provides an additional opportunity to facilitate research that will continue to advance the cutting edge of better salivary bioscience. (salimetrics.com)
Single measurements of salivary and plasmatic oxytocin are used as indicators of the physiology of the oxytocin system. (elifesciences.org)
However, questions remain about whether they are sufficiently stable to provide valid trait markers of the physiology of the oxytocin system, and whether salivary oxytocin can accurately index its plasmatic concentrations. (elifesciences.org)
Using radioimmunoassay, we measured baseline plasmatic and/or salivary oxytocin from two independent datasets. (elifesciences.org)
Salivary oxytocin is a weak surrogate for plasmatic oxytocin. (elifesciences.org)
The increases in salivary oxytocin observed after intranasal oxytocin most likely reflect unabsorbed peptide and should not be used to predict treatment effects. (elifesciences.org)
2020. Evaluating changes in salivary oxytocin and cortisol following positive reinforcement training in two adult male western lowland gorillas (Gorilla gorilla gorilla). (awionline.org)

As has been demonstrated at Zak's lab in California, one way to achieve this is by getting volunteers to inhale on an oxytocin nasal spray. (theguardian.com)
The potential problem with long-term intranasal oxytocin is nasal mucosa atrophy and it is not inexpensive. (normshealy.com)
It turns out that oxytocin has been used as a nasal spray for emotional/mental symptoms and additionally for local application to the clitoris to help vaginal dryness. (normshealy.com)
Men who reported their mothers as caring, before receiving a nasal administration of of oxytocin, felt even more highly of them after the shot. (primal-page.com)

Oxytocin injection is used to begin or improve contractions during labor. (medlineplus.gov)
If oxytocin injection is given to induce labor or to increase contractions, it is usually given intravenously with medical supervision in a hospital. (medlineplus.gov)
Your doctor may adjust your dose of oxytocin injection during your treatment, depending on your contraction pattern and on the side effects that you experience. (medlineplus.gov)
Talk to your doctor about how you are feeling during your treatment with oxytocin injection. (medlineplus.gov)
tell your doctor and pharmacist if you are allergic to oxytocin, any other medications, or any of the ingredients in oxytocin injection. (medlineplus.gov)
Your doctor will probably not give you oxytocin injection. (medlineplus.gov)
Oxytocin injection may cause side effects. (medlineplus.gov)
Your doctor may order certain lab tests to check your body's response to oxytocin injection. (medlineplus.gov)
Ask your pharmacist any questions you have about oxytocin injection. (medlineplus.gov)
Noxious stimulation activates these cells via the A1 noradrenergic relay in the pons (2) and produces analgesia by spinal release of oxytocin, since intrathecal injection of an oxytocin receptor antagonist worsens pain behaviors from peripheral inflammation (3). (centerwatch.com)
Intrathecal injection of oxytocin in normal rats reduces dorsal horn neuronal responses to noxious stimuli (6) as well as behavioral responses to noxious thermal (3), mechanical (3), and chemical (7) stimuli. (centerwatch.com)
Finally, intrathecal injection of oxytocin in rat models of chronic pain also reduces dorsal horn neuronal responses to sensory stimulation (6) as well as behavioral responses to thermal (5) and mechanical (7) stimuli. (centerwatch.com)
Post-partum hemorrhage is a significant and challenging global health issue, so we are very excited to be working with Vectura on a low cost, heat stable, and non-invasive approach to deliver oxytocin, overcoming existing limitations of current injection products," added Professor Michelle McIntosh, project lead at MIPS, in the press release. (pharmtech.com)
Two recent studies suggest that in rats, an injection of oxytocin can prevent drug-seeking behavior. (bipolarnews.org)
Healthcare providers perceived the ease of use and lack of dependence on cold storage as the main enablers for IOT compared with the current gold standard oxytocin injection. (bmj.com)
The objective of this study was to investigate the effect of IV injection of oxytocin (OT) on serum and seminal plasma levels of oestradiol (E2), testosterone (T), dehydroepiandrosterone sulphate (DHEA-S), and semen characteristics in rams. (tubitak.gov.tr)

In addition to boosting oxytocin and dopamine, being kind can also increase serotonin, a neurotransmitter that helps regulate mood. (cedars-sinai.org)

It appears that pairing oxytocin with a social norm can help counter the effects of xenophobia by enhancing altruistic behavior toward refugees. (uni-bonn.de)
This finding provided some of the first evidence that oxytocin may be a regulator of general social behavior. (sfari.org)
To directly test the function of oxytocin on social behavior, Larry Young , professor of neuroscience at Emory University in Atlanta, Georgia, examined genetically engineered mice lacking the oxytocin protein. (sfari.org)
Sue Carter and colleagues have also linked oxytocin to affiliative behavior and pair-bonding in a non-traditional animal model: the prairie vole. (sfari.org)
Because social behavior is complex, non-human primates should provide unique insights into the role of oxytocin in mediating social behavior. (sfari.org)
We were able to get rid of a big part of the social behavior induced by MDMA [by blocking oxytocin]," he says. (time.com)
The study - in collaboration with Cardiff University - has shown that therapy helps men read emotions more than dosing with oxytocin, which is released naturally and plays an important role in regulating behavior, such as emotions and personal relationships. (worldhealth.net)
Oxytocin has become a popular analyte in behavioral endocrinology in recent years, due in part to its roles in social behavior, stress physiology, and cognition. (biorxiv.org)
Oxytocin is a hormone produced in an area of the brain known as the hypothalamus, whose release activates a variety of brain regions resulting in many different functions, including birth (labor), breast feeding (lactation), maternal behavior, parental care, social bonding, affiliation (such as couples being together), and well-being. (mindandlife.org)
To determine how these neurons, dubbed oxytocin receptor interneurons or OxtrINs, affected behavior when activated by oxytocin, she silenced only this class of interneurons and, in separate experiments, blocked the receptor's ability to detect oxytocin in some females. (nutritionreview.org)
Oxytocin responses have been studied in many parts of the brain, and it is clear that it, or other hormones like it, can impact behavior in different ways, in different contexts and in response to different physiological cues," he says. (nutritionreview.org)
This paper is included because it examines a possible mechanism - metabolizing of oxytocin - which could explain differences in social behavior among dogs and which may extend to such differences among people. (nationalcanineresearchcouncil.com)
This suggests that the gaze shifting behavior may be linked to something other than social reassurance, or that oxytocin affects other sorts of emotional responses than the target of the investigation here, among other possibilities, and underlies the complexity of labeling a specific behavior as a surrogate for an aspect of personality. (nationalcanineresearchcouncil.com)

Doctors in North America and elsewhere often use a synthetic form of oxytocin, called pitocin, to induce labor, even though little is known about the long-term consequences for either mother or baby, according to Sue Carter, co-director of the Brain-Body Center at the University of Illinois at Chicago. (sfari.org)
One important consideration is what form of oxytocin to use. (pwsausa.org)

The oxytocin receptor - which directs changes in the cell in response to oxytocin - shows considerable variation both within and among species, however. (sfari.org)
4 The stimulation requires a delicate balance between the wish for progression of labour and the risks to the fetus and mother of uterine hyperstimulation, defined as more than five contractions in 10 minutes in response to oxytocin. (bmj.com)

Under the influence of oxytocin, the individuals who tended to show a positive attitude towards refugees doubled their donations to both the locals and the refugees. (uni-bonn.de)

The present review summarizes what is known about the function of oxytocin in the male mammal and tries to take account of both central and systemic effects, and those linked with a local production of oxytocin within the male reproductive organs. (drugs.com)
This molecule had not been associated with human social behaviors until my group developed a technique to stimulate and measure the brain's acute production of oxytocin through rapid blood draws. (berkeley.edu)

Oxytocin is best known for its use in inducing labour. (theguardian.com)
Today, synthetic oxytocin, also called Pitocin or Syntocinon, is often used to induce labour and to help new mothers who have trouble with milk let-down. (theguardian.com)
Objective To determine whether discontinuing oxytocin stimulation in the active phase of induced labour is associated with lower caesarean section rates. (bmj.com)
Participants 1200 women stimulated with intravenous oxytocin infusion during the latent phase of induced labour. (bmj.com)
Intervention Women were randomly assigned to have their oxytocin stimulation discontinued or continued in the active phase of labour. (bmj.com)
5 6 7 Different approaches to oxytocin administration have been suggested, such as pulsatile or intermittent administration, 8 9 an automatic feedback system, 10 high versus low dose, 11 and/or discontinuation of the stimulation when the active phase of labour is reached. (bmj.com)
Four meta-analyses and two more recent studies have suggested that once a woman is in active labour, the labour will continue even if oxytocin stimulation is stopped, resulting in a lower risk of caesarean section for fetal indications secondary to uterine hyperstimulation. (bmj.com)
Oxytocin may reduce blood loss and the need for additional uterotonics when given prophylactically in the third stage of labour, and therefore could be considered as a component of AMTSL. (cochrane.org)
How much synthetic oxytocin is infused during labour? (bournemouth.ac.uk)
OBJECTIVE: To compare synthetic oxytocin infusion regimens used during labour, calculate the International Units (IU) escalation rate and total amount of IU infused over eight hours. (bournemouth.ac.uk)
SAMPLE: National, regional or institutional-level regimens on oxytocin for induction and augmentation labour. (bournemouth.ac.uk)
CONCLUSION: Current variations in oxytocin regimens for induction and augmentation of labour are inexplicable. (bournemouth.ac.uk)
Most of you have heard me going on and on about the power of oxytocin in healing, bonding and labour. (birthbliss.ca)
IMSEAR at SEARO: Transplacental asymptomatic hyponatremia following oxytocin infusion during labour. (who.int)
The costs of induction of labour by prostaglandin E2 or oxytocin : refining the estimates / Linda Davies, Michael Drummond. (who.int)

Oxytocin clearly increases generosity towards those in need, however, if this altruistic fundamental attitude is missing, the hormone alone cannot create it," says Hurlemann. (uni-bonn.de)
T]he results of our study indicate that a 24 IU single-dose administration of OXT [oxytocin] increases fear extinction-related frontal brain activity and connectivity, and dampens fear and safety-related amygdalar activity along with electrodermal responses," the investigators, led by Monika Eckstein, PhD student from the Department of Psychiatry and the Division of Medical Psychology at the University of Bonn, Germany, write. (medscape.com)
In our study, we hypothesized that the mind-body therapies would increase oxytocin levels, which would be associated with improvements in sleep, increases in quality of life and well-being, and reduced stress. (mindandlife.org)
Physiological changes following PRT, for example, increases in oxytocin (OXT) and/or decreases in cortisol. (awionline.org)
Physical contact also increases a mother's oxytocin levels, which can help breastmilk flow. (cdc.gov)

The oxytocin-MDMA link has also been shown in rats, according to Iain McGregor, professor of psychopharmacology at the University of Sydney. (time.com)
In previous rat studies, researchers have found that the release of oxytocin is not involved in the high of amphetamine (whose effects are more similar to those of methamphetamine than MDMA's are) - and that blocking the hormone had no effect on rats' desire for the drug. (time.com)
Conversely, blocking oxytocin did decrease rats' interest in MDMA, suggesting that the hormone may be involved in ecstasy's "high. (time.com)
McGregor found that giving rats oxytocin made them lose interest in taking methamphetamine. (time.com)
In the present study, we reveal that oxytocin is released within the brain, specifically within the hypothalamic paraventricular nucleus, of male rats during mating with a receptive female. (dericbownds.net)

The participants concluded that researchers should aim to better understand the oxytocin system in people. (sfari.org)
Researchers identified oxytocin more than 100 years ago when they discovered that it regulates uterine contraction and milk ejection. (sfari.org)
Bales and Young are mapping the distribution of the oxytocin receptor within the titi monkey brain, which could help researchers understand where oxytocin functions in the human brain. (sfari.org)
The researchers wanted to determine if oxytocin was necessary for heart regeneration in a living organism. (bigthink.com)
To determine if that burst of love hormone is necessary for regenerating heart tissue, the researchers injected some of the cyro-injured zebrafish with an oxytocin inhibitor. (bigthink.com)
That would allow the researchers to enroll more patients and do more testing which could provide more definitive information regarding oxytocin. (pwsausa.org)
Researchers have found that the loved-up effects of ecstasy (MDMA) are due at least in part to oxytocin. (time.com)
Now, researchers from Michigan State University show that in zebrafish and human cell cultures, oxytocin has yet another, unsuspected, function: it stimulates stem cells derived from the heart's outer layer (epicardium) to migrate into its middle layer (myocardium) and there develop into cardiomyocytes, muscle cells that generate heart contractions. (neurosciencenews.com)
The researchers hypothesized that the different jobs that historical ancestors of these modern breeds were selected for would affect their responses both to the tests in general and to their sensitivity to oxytocin, a chemical the authors expected to facilitate social contact. (nationalcanineresearchcouncil.com)

Kovács, Kis, Pogány, Koller, & Topál (2016) studied the effects of oxytocin on social cognition in dogs, specifically breed differences on task performance previously used to demonstrate social cognition. (nationalcanineresearchcouncil.com)

Oxtr PBN neurons were directly innervated by oxytocin neurons in the paraventricular hypothalamus (Oxt PVH neurons), which mildly attenuated fluid intake. (nature.com)
To evaluate the role of oxytocin-related neural circuitry on ingestive behaviors, we generated mice expressing Cre recombinase at the Oxtr locus (Supplementary Fig. 1 ). (nature.com)
To characterize the effects of oxytocin on Oxtr PBN neurons, we recorded the activity of fluorescently labeled cells in brain slices and observed that bath application of Thr 4 ,Gly 7 -oxytocin (TGOT), a selective Oxtr agonist, efficiently activated Oxtr PBN neurons, and this activation was blocked by coadministration of atosiban (oxytocin-receptor antagonist), which confirmed the specificity of the activation (Fig. 1c and Supplementary Fig. 2d ). (nature.com)
To fulfill its many roles, oxytocin has to dock at a protein called the 'oxytocin receptor', encoded by a gene called OXTR. (discovermagazine.com)
The neural basis of smile authenticity judgments and the potential modulatory role of the oxytocin receptor gene (OXTR). (cdc.gov)

Glu 1.35 in transmembrane helix 1 (TM1) of the human oxytocin receptor (OTR) is absolutely conserved in all OTRs cloned to date. (monash.edu)

There is "an inverse correlation between plasma oxytocin and the volume of the right amygdala and the right hippocampus, 2 brain areas implicated in fear and anxiety. (normshealy.com)

Oxytocin-expressing neurons are located in the paraventricular nucleus of the hypothalamus (PVH) and supraoptic nucleus (SON) and project axons to the posterior pituitary to release oxytocin peripherally 1 . (nature.com)
Enjoy and remember, think soft thoughts…they release oxytocin! (birthbliss.ca)
I did not know that soft words release oxytocin, so there we have it…another reason why it's sooooo important for HypnoBirthing parents to embrace the terminology. (birthbliss.ca)

I proved that the brains of indigenous people produce oxytocin and this makes heavy work light. (berkeley.edu)
In all the emotional disorders listed at the beginning, intranasal sprays of oxytocin have been proven to improve the emotional problem, BUT intranasal sprays have to be done 4 times a day, and have no ability to restore the brain's ability to produce oxytocin. (normshealy.com)

It turns out, however, that oxytocin is not the common denominator between the two drugs - MDMA may increase oxytocin, while methamphetamine may not affect it directly. (time.com)

Effects of Exogenous Oxytocin on Serologic and Seminal Steroids and Se" by TANZER BOZKURT, GAFFARİ TÜRK et al. (tubitak.gov.tr)

Similarly, direct electrical stimulation of the PVN reduces behavioral sensitivity in a model of chronic neuropathic pain, and this effect is blocked by an oxytocin receptor antagonist (5). (centerwatch.com)
Furthermore, blockade of the activated brain oxytocin system by central administration of an oxytocin receptor antagonist immediately after mating prevents the anxiolytic effect of mating, while having no effect in nonmated males. (dericbownds.net)

The purpose of this study is to determine the effect of intrathecal oxytocin on areas and intensity of hyperalgesia and allodynia induced by topical capsaicin. (centerwatch.com)
Objectives: Determine the effect of intrathecal oxytocin on areas and intensity of hyperalgesia and allodynia induced by topical capsaicin. (centerwatch.com)

The neuropeptide, oxytocin (OT), has well-established roles during parturition and lactation. (scirp.org)
The neuropeptide oxytocin has been shown to exert multiple functions in male and female reproduction, and to play a key role in the regulation of emotionality after its peripheral and central release, respectively. (dericbownds.net)

Objective This study assessed the potential operational feasibility and acceptability of a heat-stable, inhaled oxytocin (IOT) product for community-based prevention of postpartum haemorrhage in Myanmar. (bmj.com)
This is the first qualitative inquiry exploring the operational feasibility and acceptability of a future heat-stable, inhaled oxytocin (IOT) product for community-based prevention of postpartum haemorrhage in Myanmar to inform product development. (bmj.com)

Contractility of uterine smooth muscle can be controlled by hormonal and neural factors examples progesterone, oxytocin and prostaglandin F2α (PGF2α) (hormonal) and acetylcholine (neural). (medsci.org)

Direct electrical stimulation of the PVN reduces dorsal horn neuronal responses to noxious stimulation, and this is blocked by administration of sequestering antibody for oxytocin (4). (centerwatch.com)
Conclusions In a setting where monitoring of the fetal condition and the uterine contractions can be guaranteed, routine discontinuation of oxytocin stimulation may lead to a small increase in caesarean section rate but a significantly reduced risk of uterine hyperstimulation and abnormal fetal heart rate patterns. (bmj.com)
1 2 3 This often includes stimulation with oxytocin. (bmj.com)
No evidence indicated gastrin alterations or muscular damage from touristic mushing, but an oxytocin increase would indicate a stimulation of the brain reward system. (conicet.gov.ar)

The pituitary also secretes endorphins (pronounced: en-DOR-fins), chemicals that act on the nervous system and reduce feelings of pain. (kidshealth.org)
To get more specific, research has shown that crying releases unique hormones in the body , such as oxytocin and endorphins, which help relieve physical and psychological pain while reducing other stress-related hormones such as adrenocorticotropic hormone (ACTH). (mindbodygreen.com)

The second is that single measures provide reliable estimates of baseline levels of endogenous oxytocin in plasma or saliva. (elifesciences.org)
Currently, we lack robust evidence that single measures of endogenous oxytocin in saliva and plasma at rest are stable enough to provide a valid trait marker of the activity of the oxytocin system in healthy individuals. (elifesciences.org)
Mechanical methods work by directly causing cervical dilation and also by releasing endogenous prostaglandins and oxytocin. (medscape.com)
The Effect on the Birth Process of Endogenous Oxytocin Release Via Coitus at Home in Pregnant Women in the Latent Phase. (bvsalud.org)
This study was conducted to determine the effect of endogenous oxytocin release via coitus at home on the delivery process in pregnant women who were not hospitalized in the latent phase. (bvsalud.org)

Vectura, an inhalation contract development and manufacturing organization (CDMO), announced on Sept. 14, 2020 that it has partnered with Monash University's Institute of Pharmaceutical Sciences (MIPS) for the development of an inhaled oxytocin delivered by a dry-powder inhaler to prevent postpartum hemorrhage (PPH) in childbirth. (pharmtech.com)

The men also provided blood samples to record their oxytocin levels, the hormone that in women triggers labor and lactation and in men has a role in moving sperm. (littlethaifoodataustin.com)
While Blessed Thistle Mediterranean herb and dandelion-like blossoms stimulate healthy immune response and increase prolactin, the oxytocin hormones stimulate lactation, using anethole substances from fennel seed that produce breast milk secretion. (athleticinsight.com)

If not, further pharmacologic agents (i.e. oxytocin) can be used for induction. (medscape.com)
Again, the need for amniotomy , labor induction with oxytocin , analgesics and episiotomy decreased. (bvsalud.org)
Once detected, H-Mole is removed through dilatation and curettage, but if discovered later induction by oxytocin may be done to expel the abnormal growth. (healthwatchcenter.com)

We know it is oxytocin causing cooperation because my colleagues and I developed a way to safely infuse synthetic oxytocin into living human brains. (berkeley.edu)
It is crucial that the appropriate minimum infusion regimen is administered because synthetic oxytocin is a potentially harmful medication with serious consequences for women and babies when inappropriately used. (bournemouth.ac.uk)

Results A total of 607 women were assigned to discontinuation and 593 to continuation of the oxytocin infusion. (bmj.com)
METHODS: Data on oxytocin IU dose, infusion fluid amount, start dose, escalation rate and maximum dose were collected. (bournemouth.ac.uk)
Estimating the total amount of oxytocin IU received by labouring women, alongside the institution's mode of birth and neonatal outcomes, may deepen our understanding and be the way forward to identifying the optimal infusion regimen. (bournemouth.ac.uk)

When we finally speak, Zak tells me that "oxytocin is primarily a molecule of social connection. (theguardian.com)
Injecting oxytocin into the brain of prairie voles induces formation of these bonds and injecting a molecule that blocks the oxytocin receptor prevents them, studies have shown. (sfari.org)
Prior patent literature and recent proteomic research in plasma and serum has appreciated that oxytocin exists as a cyclic active molecule and also in a pool with disulfides linked to other proteins. (salimetrics.com)

Aguirre and his team identified 15 candidates, including growth hormone (which is undergoing clinical studies to determine muscle regeneration in severely burned patients), prolactin (which regulates liver regeneration in mice), and oxytocin (which is necessary for muscle maintenance and regeneration ). (bigthink.com)

Because oxytocin is most involved in social behaviors of females, we decided to focus our experiments on females. (nutritionreview.org)

Google Académico, fueron incluidas únicamente las publicaciones que se encontraron a texto completo, en español, inglés y portugués durante los años 2014 al 2022. (bvsalud.org)

According to their study , oxytocin stimulates stem cells to develop into cardiomyocytes - the muscle cells that generate heart contractions and which are damaged during a heart attack. (bigthink.com)

L istening to Paul Zak extol the virtues of oxytocin, the "love hormone", is like hearing a preacher sing the praises of the Promised Land. (theguardian.com)
Oxytocin, the "love hormone", is one of those blood factors that we have less of as we age. (hplusmagazine.com)
Describing oxytocin as the "hormone of love" is like describing a computer as a "writing tool" - it does other things too, some of which aren't pleasant. (discovermagazine.com)
Oxytocin, a hormone connected with bonding and love, could help to heal damage following a heart attack. (neurosciencenews.com)
Oxytocin, the body's natural love potion, helps couples fall in love, makes mothers bond with their babies, and encourages teams to work together. (nutritionreview.org)
As you might recall, oxytocin is the "love hormone," but it is also referred to as the "anti-stress" hormone. (birthbliss.ca)
He has also been coined "Dr. Love" based on his research on how oxytocin influences economic decisions. (birthbliss.ca)
Levels of oxytocin, the so-called love hormone, and activation in certain parts of the brain may help predict how men will behave as parents, a small study in Developmental Psychobiology showed. (littlethaifoodataustin.com)
Also known as the 'love drug' because when you hug someone or feel a sense of belonging your brain reacts with Oxytocin. (nofun.io)
Therefore, we love to give back to others and make ourselves happy with an oxytocin boost. (phytogenius.com)
Oxytocin isn't love. (timdenning.com)

Within two years, doctors were using oxytocin to bring on childbirth contractions. (theguardian.com)
Oxytocin is a uterotonic medication that promotes increased uterine tone and contractions, and is commonly administered immediately following delivery of the infant's shoulder as part of AMTSL. (cochrane.org)
Oxytocin acts on SMOOTH MUSCLE CELLS , such as causing UTERINE CONTRACTIONS and MILK EJECTION . (bvsalud.org)

Updated Nov. 7, 2014) Intranasal oxytocin (multiple brands) may enhance fear extinction therapy for patients with anxiety disorders, preliminary research suggests. (medscape.com)
The findings on oxytocin may well lead to some new treatments for autism, McGregor suggests, given that autistic people have difficulty making the oxytocin-driven connection between people and pleasure. (time.com)
Our current understanding of how oxytocin sprays work suggests that, in their current form, it may not be a practical solution. (worldhealth.net)
Because the literature suggests different oxytocin response timing to different stimulus, Salimetrics recommends running a small pilot study to determine peak sample collection timing. (salimetrics.com)

Oxytocin, the hormone that promotes emotional bonding, also regulates a variety of behaviors. (bipolarnews.org)

In addition, the oxytocin reversed changes in the brain's glutamate signaling pathway that were caused by cocaine use. (bipolarnews.org)

That was a single "dose", and there are numerous studies that demonstrate improvement in all negative emotions with continuing inhalation of oxytocin. (normshealy.com)
Main Outcome Measures Oxytocin IU dose infused. (bournemouth.ac.uk)
When used as prophylaxis within 10 min after vaginal delivery usually at the dose of 1 g IV, in addition to standard prophylaxis with oxytocin, tranexamic acid reduced the risk of primary PPH and the mean post-partum blood loss However there are no studies that evaluated the impact of TA on blood loss after vaginal deliveries with an episiotomy. (centerwatch.com)

Dale later discovered that oxytocin stimulated the release, or let-down, of mother's milk by contracting the smooth-muscle cells around the mammary glands. (theguardian.com)

Still, the findings provide "important mechanistic insights into beneficial effects of oxytocin in fear extinction, which is thought to be the key learning process underlying cognitive behavioral therapy (exposure) of anxiety disorders," said Dr Hurlemann. (medscape.com)
And it supports some findings from our own laboratory suggesting that oxytocin can facilitate aspects of fear extinction learning," he added. (medscape.com)
In this webinar we will have two panelists discussing the role of oxytocin from findings in Nigeria and India. (rhsupplies.org)
These findings provide direct evidence for an essential role of an activated brain oxytocin system mediating the anxiolytic effect of mating in males. (dericbownds.net)

My experiments in the early 2000s on human cooperation were the first to identify the key role played by the neurochemical oxytocin. (berkeley.edu)

Study limitations cited included the fact that fear acquisition and extinction were performed on the same day instead of being spread out over several days and that it is not known whether the effects of oxytocin can be extrapolated from the type of fear conditioning used here to other types, such as evaluative conditioning. (medscape.com)
For now, Bartz isn't sure why oxytocin can have such different effects. (discovermagazine.com)
In particular, the beneficial effects of oxytocin that we want to bolster only last for several hours. (worldhealth.net)
Oxytocin (OXT), a neurohypophyseal hormone, has a wide range of behavioral effects outside its classic peripheral endocrine functions. (erowid.org)
This study, which seemed to contradict our established knowledge of the effects of oxytocin, was described in the November 29, 2010 journal, Proceedings of the National Academy of Science . (primal-page.com)
Investigating oxytocin in cancer survivors could be important, given cancer survivors' high levels of distress, depression, and anxiety, as well as poor sleep, possibly due to the effects of cancer treatment and worries about cancer recurrence. (mindandlife.org)
Regarding the effects of the mind-body therapies, after controlling for baseline differences among groups, post-treatment oxytocin levels were significantly higher in the mind-body bridging group as compared with those in the control group. (mindandlife.org)
Although exogenously application of oxytocin (OT) hormone researches are increasing for the effects of brain and related pathophysiologies, epilepsy-related studies are highly limited. (mendeley.com)
Therefore, in this study, effects of BPA, vinclozolin and DDT-only and in combination with uterotonins (PGF-2α, acetylcholine and oxytocin) on the force and pattern of uterine contraction were observed. (medsci.org)

As a result of that research, McGregor and his colleagues are now testing intranasal oxytocin to help reduce addiction in alcoholics and heavy pot smokers. (time.com)
Dr. Katie Daughters says the research, which was carried out with colleagues in Cardiff, revealed we need to know more about oxytocin before using it as a treatment. (worldhealth.net)
Writing in Science , Azabu University researcher Miho Nagasawa and her colleagues compared urine oxytocin levels in a group of dogs and their owners before and after the spent time interacting with each other. (thenakedscientists.com)

But Zak goes further, arguing that many of the social and political issues that currently seem so intractable could be solved if only we could find a way of raising people's basal levels of oxytocin. (theguardian.com)
High levels of oxytocin cause people to work harder to help the group achieve its goals. (berkeley.edu)
Paul Zak speaks about his research on oxytocin levels in the blood which when increased, generate more positive human behaviors. (csun.edu)
Zak showed several clips on studies he had conducted from measuring oxytocin levels in blood before and after a wedding to mishaps during his research in Papua New Guinea. (csun.edu)
Through all of his studies, Zak measured oxytocin levels through blood samples. (csun.edu)
Oxytocin levels decline with age, and this summer, there was an article in Nature suggesting that it may be one of those signals that help to keep us young. (hplusmagazine.com)
Maybe when you get high levels of oxytocin, plus high levels of dopamine, you have a motivational situation where you are strongly oriented toward [people]," McGregor says. (time.com)
Overall, oxytocin levels did not differ between females and males and were not correlated with age. (mindandlife.org)
400 UI/L), low and stable levels of gastrin (9.4 ± 8.8 pg/mL), and a slight increase in oxytocin (23%) after mushing activities. (conicet.gov.ar)
Those with higher oxytocin levels in their blood had a more baby-led approach. (littlethaifoodataustin.com)
This is the first study to analyze oxytocin levels and brain activation in fathers. (littlethaifoodataustin.com)

Oxytocin is in a class of medications called oxytocic hormones. (medlineplus.gov)

Different strategies have been described for preventing and treatment PPH, including active management of the third stage of labor, among them uterine massage and controlled cord traction in addition to oxytocin and the use of Tranexamic acid (TA) as PPH treatment Tranexamic acid (TA) is a lysine analog, which acts as an antifibrinolytic via competitive inhibition to the binding of plasmin and plasminogen to fibrin. (centerwatch.com)

Using this protocol, we showed that when one is intentionally trusted, even by a stranger, the brain produces oxytocin. (berkeley.edu)
In fact, this response is graded: The more trust one is shown by others, the more oxytocin is released in the brain. (berkeley.edu)
Within three days after cryo-injury, oxytocin RNA expression in the brain increased 18-fold and lasted for at least seven days, suggesting that a burst of oxytocin is released from the brain into the bloodstream after cardiac injury over a sustained period. (bigthink.com)
We published a paper last year showing that baclofen strongly activated oxytocin in the rat brain," says McGregor. (time.com)
Within some profiles from the outer layer of the brain known as the cortex, she saw an intriguing protein: a receptor that responds to oxytocin. (nutritionreview.org)
Prairie voles still form social bonds without oxytocin sensors in the brain. (newscientist.com)
Intranasal oxytocin modulates brain responses to voice-identity recognition in typically developing individuals, but not in ASD. (mpg.de)
The brain releases Oxytocin in experiences associated with trust, friendship and connection. (nofun.io)

These results concur with animal research suggesting an essential role for oxytocin as a biological basis of prosocial approach behaviour. (nih.gov)
Finally, oxytocin in seminal fluid is discussed and its possible role in respect to the fate of the semen following ejaculation. (drugs.com)
I also went as far from the developed world as I could to test the role of oxytocin on teamwork to convince myself that the neural signatures of cooperation were universal. (berkeley.edu)
This position backed up the idea that oxytocin may somehow play a role in the formation of these memories. (primal-page.com)

Oxytocin-deficient mice don't develop this familiarity despite showing normal discrimination of non-social stimuli such as fruit scents. (sfari.org)
Aging mice with extra oxytocin retained muscle mass that was lost by mice of similar age as their oxytocin naturally declined. (hplusmagazine.com)
Using samples from oxytocin knockout (KO) and wildtype (WT) mice, we find evidence of considerable interference in unextracted urine samples, with similar distributions of measured oxytocin in both genotypes. (biorxiv.org)
We present a new mixed-mode cation-exchange SPE method that minimizes interference-with knockout samples measuring below the assay's limit of detection-while effectively retaining oxytocin from the urine of wildtype mice. (biorxiv.org)
By identifying a new population of neurons activated by oxytocin, we have uncovered one way this chemical signal influences interactions between male and female mice," says Nathaniel Heintz, James and Marilyn Simons Professor and head of the Laboratory of Molecular Biology. (nutritionreview.org)
The interesting part is that when exposed to oxytocin these neurons fire more frequently in female mice than they do in male mice, possibly reflecting the differences that showed up in the behavioral tests. (nutritionreview.org)
We don't yet understand how, but we think oxytocin prompts mice in estrus to become interested in investigating their potential mates," Nakajima says. (nutritionreview.org)

Biochemically, you can't live on the 3-to-4-minute oxytocin boost that comes from a single act. (cedars-sinai.org)
Oxytocin can boost heart cells' ability to regenerate. (bigthink.com)

Anatomy8

Organisms1

Diseases2

Chemicals and Drugs12

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Psychiatry and Psychology3

Phenomena and Processes9

Vasopressin stimulation of acetate incorporation into lipids in a dimethylbenz(a)anthracene-induced rat mammary tumor cell line. (1/1958)

Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. (2/1958)

Production of prostaglandin f2alpha and its metabolite by endometrium and yolk sac placenta in late gestation in the tammar wallaby, Macropus Eugenii. (3/1958)

Down-regulation of oxytocin-induced cyclooxygenase-2 and prostaglandin F synthase expression by interferon-tau in bovine endometrial cells. (4/1958)

Oxytocin and vasopressin receptors in human and uterine myomas during menstrual cycle and early pregnancy. (5/1958)

Desensitization of oxytocin receptors in human myometrium. (6/1958)

Uterine peristalsis during the follicular phase of the menstrual cycle: effects of oestrogen, antioestrogen and oxytocin. (7/1958)

Sperm transport in the human female genital tract and its modulation by oxytocin as assessed by hysterosalpingoscintigraphy, hysterotonography, electrohysterography and Doppler sonography. (8/1958)

Oxytocin

Oxytocics

Vasotocin

Vasopressins

Milk Ejection

Supraoptic Nucleus

Neurophysins

Pituitary Gland, Posterior

Uterine Contraction

Myometrium

Dinoprost

Labor, Obstetric

Ornipressin

Uterus

Pregnancy

Paraventricular Hypothalamic Nucleus

Progesterone

Lactation

Labor, Induced

Estrus

Corpus Luteum

Hypothalamus

Luteolysis

Maternal Behavior

Pregnancy, Animal

Pair Bond

Social Behavior

Sheep

Tocolytic Agents

Hormone Antagonists

Lypressin

Endometrium

Postpartum Hemorrhage

Prostaglandins F

Labor Stage, Third

Uterine Inertia

Vasopressin stimulation of acetate incorporation into lipids in a dimethylbenz(a)anthracene-induced rat mammary tumor cell line. (1/1958)

Central peptidergic neurons are hyperactive during collateral sprouting and inhibition of activity suppresses sprouting. (2/1958)

Production of prostaglandin f2alpha and its metabolite by endometrium and yolk sac placenta in late gestation in the tammar wallaby, Macropus Eugenii. (3/1958)

Down-regulation of oxytocin-induced cyclooxygenase-2 and prostaglandin F synthase expression by interferon-tau in bovine endometrial cells. (4/1958)

Oxytocin and vasopressin receptors in human and uterine myomas during menstrual cycle and early pregnancy. (5/1958)

Desensitization of oxytocin receptors in human myometrium. (6/1958)

Uterine peristalsis during the follicular phase of the menstrual cycle: effects of oestrogen, antioestrogen and oxytocin. (7/1958)

Sperm transport in the human female genital tract and its modulation by oxytocin as assessed by hysterosalpingoscintigraphy, hysterotonography, electrohysterography and Doppler sonography. (8/1958)

Oxytocin for Depression - Oxytocin Accelerator

Oxytocin | San Diego Sexual Medicine

Sex-specific effects of intranasal oxytocin on thermal pain perception: A randomised, double-blind, placebo-controlled cross...

Inhibitory effect of barusiban and atosiban on oxytocin-induced contractions of myometrium from preterm and term pregnant women...

Oxytocin as a neurotransmitter: beyond the peripheral scope] | eLitMed

Study finds plasma oxytocin levels higher in OC users | Contemporary OB/GYN

China Oxy Acetate 2mg Hasten Parturition Peptides Oxytocin - China Oxytocin Price, Oxytocin Injection

Low Oxytocin Linked to Postpartum Depression - Oxytocin Accelerator

Plasma vasopressin, oxytocin, estradiol, and progesterone related to water and sodium excretion in normal pregnancy and...

Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance | PNAS

Oxytocin administration suppresses hypothalamic activation in response to visual food cues

Safety Study of Intranasal Oxytocin in Frontotemporal Dementia - Full Text View - ClinicalTrials.gov

INACTIVATION OF OXYTOCIN AND SYNTHETIC OXYTOCIN ANALOGUES BY HEN TISSUES in: Journal of Endocrinology Volume 63 Issue 2 (1974)

Can Oxytocin be whats missing in the Alcoholic Hole in the Soul? - Inside The Alcoholic Brain

A study to determine minimum effective dose of oxytocin infusion during caesarean delivery in parturients at high risk of...

A comparison of the effect of nipple stimulation and oxytocin infusion on the duration of phases of labor | Journal of...

Oxytocin Add-on Study for Stable Anxiety Patients - Full Text View - ClinicalTrials.gov

Oxytocin, Adrenocorticotropic Hormone and Cortisol: Roles of Oxytocin by Amira Athanasios

Release of oxytocin during suckling and parturition in the rat in: Journal of Endocrinology Volume 105 Issue 3 (1985)

oxytocin

Frontiers | Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or...

Oxytocin Hormone Promotes Social Behavior in Infant Rhesus Monkeys | Office of News & Media Relations | UMass Amherst

Oxytocin regulates Ca2+ level in myometrium by influencing phosphoinositide metabolism. - Semantic Scholar

Oxytocin Injection | Reproduction Hormone | Medi-Vet

Oxytocin Injection, Vial, USP, 10 Units/mL, 1mL | Emergency Medical Products

Oxytocin Injection (Canada) for Animal Use - Drugs.com

Frontiers | Vasopressin and Oxytocin Reduce Food Sharing Behavior in Male, but Not Female Marmosets in Family Groups |...

Oxytocin | elephantcare

Chronic oxytocin administration inhibits food intake, increase...

Target Engagement for Intranasal Oxytocin in Autism Spectrum Disorders, an fMRI Dose Response Study - AdisInsight

PART 2 - INTERVIEW PAUL ZAK, PHD - WHAT IS OXYTOCIN ? HOW CAN IT IMPROVE QOL AND HEALTHCARE OUTCOMES? - CancerLife

Visualization of oxytocin release that mediates paired pulse facilitat by Ramón A. Piñol, Heather Jameson et al.

Serotonin Gives Oxytocin a Helping Hand | Science Translational Medicine

Oxytocin Production: Increase the Love Hormone by Reducing Stress

Crazy Eddies Motie News: Are your oxytocin levels high enough?

Serotonergic involvement in stress-induced vasopressin and oxytocin secretion - Forskning - Region Hovedstaden