Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.
Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.
Compounds which increase the capacity to conceive in females.
Diminished or absent ability of a female to achieve conception.
Extracts of urine from menopausal women that contain high concentrations of pituitary gonadotropins, FOLLICLE STIMULATING HORMONE and LUTEINIZING HORMONE. Menotropins are used to treat infertility. The FSH:LH ratio and degree of purity vary in different preparations.
A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.
A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.
A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.
Human artificial insemination in which the husband's semen is used.
Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED).
Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.
The condition of carrying two or more FETUSES simultaneously.
A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central PRECOCIOUS PUBERTY and ENDOMETRIOSIS.
Occurrence or induction of release of more ova than are normally released at the same time in a given species. The term applies to both animals and humans.
Clinical and laboratory techniques used to enhance fertility in humans and animals.
Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
A protein extract of human menopausal urine in which LUTEINIZING HORMONE has been partially or completely removed. Urofollitropin represents FOLLICLE STIMULATING HORMONE from the urine.
A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
The discharge of an OVUM from a rupturing follicle in the OVARY.
The induction of local hyperthermia by either short radio waves or high-frequency sound waves.
A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications.
Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies.
An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis.
The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.
The period from onset of one menstrual bleeding (MENSTRUATION) to the next in an ovulating woman or female primate. The menstrual cycle is regulated by endocrine interactions of the HYPOTHALAMUS; the PITUITARY GLAND; the ovaries; and the genital tract. The menstrual cycle is divided by OVULATION into two phases. Based on the endocrine status of the OVARY, there is a FOLLICULAR PHASE and a LUTEAL PHASE. Based on the response in the ENDOMETRIUM, the menstrual cycle is divided into a proliferative and a secretory phase.
The period in the MENSTRUAL CYCLE that follows OVULATION, characterized by the development of CORPUS LUTEUM, increase in PROGESTERONE production by the OVARY and secretion by the glandular epithelium of the ENDOMETRIUM. The luteal phase begins with ovulation and ends with the onset of MENSTRUATION.
The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Procedures to obtain viable OOCYTES from the host. Oocytes most often are collected by needle aspiration from OVARIAN FOLLICLES before OVULATION.
The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle (OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes.
The number of births in a given population per year or other unit of time.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.
Blocking the process leading to OVULATION. Various factors are known to inhibit ovulation, such as neuroendocrine, psychological, and pharmacological agents.
The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.
An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).
The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
Proteins prepared by recombinant DNA technology.
The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.
The number of offspring produced at one birth by a viviparous animal.
Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.
Elements of limited time intervals, contributing to particular results or situations.
Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Occurrence or induction of ESTRUS in all of the females in a group at the same time, applies only to non-primate mammals with ESTROUS CYCLE.
The period of the MENSTRUAL CYCLE representing follicular growth, increase in ovarian estrogen (ESTROGENS) production, and epithelial proliferation of the ENDOMETRIUM. Follicular phase begins with the onset of MENSTRUATION and ends with OVULATION.
A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
Methods for recognizing the state of ESTRUS.
Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).
Achievement of full sexual capacity in animals and in humans.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
A state of sexual inactivity in female animals exhibiting no ESTROUS CYCLE. Causes of anestrus include pregnancy, presence of offspring, season, stress, and pathology.
The production of offspring by selective mating or HYBRIDIZATION, GENETIC in animals or plants.
The period of cyclic physiological and behavior changes in non-primate female mammals that exhibit ESTRUS. The estrous cycle generally consists of 4 or 5 distinct periods corresponding to the endocrine status (PROESTRUS; ESTRUS; METESTRUS; DIESTRUS; and ANESTRUS).
An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.
A phase of the ESTROUS CYCLE that precedes ESTRUS. During proestrus, the Graafian follicles undergo maturation.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.
The total process by which organisms produce offspring. (Stedman, 25th ed)
In females, the period that is shortly after giving birth (PARTURITION).
The potential of the FETUS to survive outside the UTERUS after birth, natural or induced. Fetal viability depends largely on the FETAL ORGAN MATURITY, and environmental conditions.
A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
Peptides, natural or synthetic, that stimulate the release of PITUITARY HORMONES. They were first isolated from the extracts of the HYPOTHALAMUS; MEDIAN EMINENCE; PITUITARY STALK; and NEUROHYPOPHYSIS. In addition, some hypophysiotropic hormones control pituitary cell differentiation, cell proliferation, and hormone synthesis. Some can act on more than one pituitary hormone.
The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.
Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.
The complex processes of initiating CELL DIFFERENTIATION in the embryo. The precise regulation by cell interactions leads to diversity of cell types and specific pattern of organization (EMBRYOGENESIS).
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Unsaturated androstanes which are substituted with one or more hydroxyl groups in any position in the ring system.
Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR) that stimulate gonadal functions in both males and females. They include FOLLICLE STIMULATING HORMONE that stimulates germ cell maturation (OOGENESIS; SPERMATOGENESIS), and LUTEINIZING HORMONE that stimulates the production of sex steroids (ESTROGENS; PROGESTERONE; ANDROGENS).
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The degeneration and resorption of an OVARIAN FOLLICLE before it reaches maturity and ruptures.
Established cell cultures that have the potential to propagate indefinitely.
Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.
The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.

Differential transcriptional activity associated with chromatin configuration in fully grown mouse germinal vesicle oocytes. (1/1572)

It was previously shown that fully grown ovarian germinal vesicle (GV) oocytes of adult mice exhibit several nuclear configurations that differ essentially by the presence or absence of a ring of condensed chromatin around the nucleolus. These configurations have been termed, respectively, SN (surrounded nucleolus) and NSN (nonsurrounded nucleolus). Work from our and other laboratories has revealed ultrastructural and functional differences between these two configurations. The aims of the present study were 1) to analyze the equilibrium between the SN and the NSN population as a function of the age of the mice and the time after hCG-induced ovulation and 2) to study the polymerase I (pol I)- and polymerase II (pol II)-dependent transcription in both types of oocytes through the detection of bromouridine incorporated into nascent RNA. We show 1) that ovarian GV oocytes exhibiting the SN-type configuration can be found as soon as 17 days after birth in the C57/CBA mouse strain and 2) that the SN:NSN ratio of ovarian GV oocytes is very low just after hCG-induced ovulation and then increases progressively with the time after ovulation. Furthermore, we demonstrate that the SN configuration correlates strictly with the arrest of both pol I- and pol II-dependent transcription in mice at any age. Finally, we show that ribosomal genes are located at the outer periphery of the nucleolus in the NSN configuration and that pol I-dependent perinucleolar transcription sites correspond to specific ultrastructural features of the nucleolus. Altogether, these results provide clear-cut criteria delineating transcriptionally active GV oocytes from those that are inactive, and confirm that the SN-type configuration is mostly present in preovulatory oocytes.  (+info)

Ovarian follicular responses in dairy cows treated with GnRH and cloprostenol. (2/1572)

Lactating, nonpregnant (with a corpus luteum) Holsteins were given 100 ug GnRH (n = 12) or saline (n = 12) and 500 ug cloprostenol 6 d later. Following luteolysis, ovulation occurred 10.1 +/- 0.2 d (range, 9-12 d) after GnRH and 8.6 +/- 1.0 d (range, 3-12 d) after saline (differences between groups: means, P > 0.05; variability, P < 0.001). Treatment with GnRH and cloprostenol resulted in a relatively synchronous ovulation.  (+info)

Effect of exogenous gonadotropins on gonadotrophs of the rat pituitary gland. (3/1572)

In the human in vitro fertilization (IVF) program a variety of superovulation regimens have been employed to promote follicular stimulation and the recruitment of supernumerary oocytes. This therapy, however, disturbs serum concentrations of estradiol and progesterone and may disrupt the normal feedback systems of the hypothalamo-pituitary axis. This study examines the effects of hyperstimulation on the pituitary gonadotrophs and circulating gonadotrophins. FSH and human chorionic gonadotropin (hCG) were administered to normal cycling female Sprague-Dawley rats (n = 12) in phase with their estrous cycle. Control rats (n = 12) were injected with saline. In both the experimental and control groups, six rats were mated on the evening of proestrus and killed 12 hr later, while six animals were killed prior to mating. Blood was collected at the time of sacrifice for radioimmunoassay. The pituitary glands were removed, processed for light microscopy and serially sectioned. Immunocytochemistry for LH and FSH was carried out to determine the area occupied by these cell types. Data were statistically analyzed. Findings were correlated with circulating levels of LH, FSH, estradiol and progesterone. RIA revealed that the concentration of LH, FSH, estradiol and progesterone were significantly different with respect to hyperstimulation and mating. In addition the area occupied by LH and FSH cells was significantly different with respect to both hyperstimulation and mating. Hyperstimulation affects gonadotroph content, as well as gonadotropin and sex steroid hormone concentrations and together with other factors, may disrupt the ideal environment required for implantation.  (+info)

Is there a difference in the function of granulosa-luteal cells in patients undergoing in-vitro fertilization either with gonadotrophin-releasing hormone agonist or gonadotrophin-releasing hormone antagonist? (4/1572)

Gonadotrophin-releasing hormone (GnRH) regulates gonadotrophin release. It has been shown that GnRH may have a direct effect on the ovary, as the addition of GnRH to granulosa cell cultures inhibits the production of progesterone and oestradiol. Specific GnRH receptors have been found to be present in rat and human granulosa cells. Desensitization of the pituitary by GnRH agonist has become common in in-vitro fertilization (IVF) treatment, usually by a long protocol of 2-3 weeks. With the introduction of GnRH antagonists, which produce an immediate blockage of the GnRH receptors, a much shorter exposure is needed of 3-6 days. The aim of this study was to evaluate the effect of a GnRH agonist (buserelin) and a GnRH antagonist (cetrorelix) on the function of granulosa cells cultured in vitro from IVF patients. Women were treated by IVF randomized either to have buserelin nasal spray from the luteal phase in the previous cycle or cetrorelix from day 6 of the cycle. Both groups had ovarian stimulation with human menopausal gonadotrophin (HMG) 150 IU daily, i.e. HCG was administered when the follicles were larger than 17 mm, and aspirated 36 h later. Granulosa cells, separated and washed from large follicles containing ova, were pooled. After 48 h of pre-incubation, the granulosa cells were cultured for 4 days in medium with either added testosterone or cAMP with or without HCG, with change of medium after 2 days. The progesterone and oestradiol concentrations in the culture medium were measured by immunological assay, and cellular protein was measured by microprotein assay. The results showed that granulosa cells from women treated with GnRH antagonist (cetrorelix) responded earlier to the in-vitro hormone stimulation in terms of progesterone accumulation than women treated with the GnRH agonist (buserelin). This may have been due to difference in time of exposure to the analogue. The results may indicate that the luteal function is less impaired in GnRH antagonist treatment than in GnRH agonist treatment.  (+info)

Pharmaco-economic aspects of in-vitro fertilization in Italy. (5/1572)

Given the higher efficacy of follitropin-beta, a new recombinant follicle stimulating hormone (r-FSH), versus urinary-FSH (u-FSH), the present study was carried out to evaluate the cost-effectiveness ratio (CER) of follitropin-beta in comparison with u-FSH in women undergoing in-vitro fertilization (IVF) in Italy. Clinical decision analysis techniques were used to retrospectively model the direct medical costs of women undergoing IVF treatment. Seven Italian experts were interviewed, using a semi-structured questionnaire, in order to adapt the results of all clinical trials to the Italian patterns of care. Three analyses were conducted considering the public, the private sectors and a mixture of them (currently representing the Italian situation). The estimated total cost of IVF treatments varies from 106.9 and 211.7 billion Lire (63.2 and 125.2 million US$) depending on setting and type of treatment. The average CER varies from 21.5 and 37.7 million Lire (12, 700 and 22,300 $US) in the different hypotheses considered. The incremental CER varies from 19.2 and 26.0 million Lire (11,300 and 15,400 $US) depending on setting and type of treatment.  (+info)

Poor responders to ovulation induction: is proceeding to in-vitro fertilization worthwhile? (6/1572)

A 'poor response' in the context of in-vitro fertilization (IVF) can be defined as failure to produce an adequate number of mature follicles, and/or a peak oestradiol concentration less than a defined minimum. The cut-off points implied in this definition vary between different centres. Many opt to cancel the IVF cycle when their defined minimum concentrations are not reached despite the lack of evidence of improved outcome in subsequent cycles. Patients attending the Oxford Fertility Unit who are 'poor responders' have always been given the option of continuing with treatment. The first cycles of IVF in 124 patients, with normal day 3 follicle stimulating hormone (FSH), who produced less than five follicles within a 2 year period were studied. The patients were divided into three groups according to the number of follicles produced: A (one or two follicles; n = 33), B (three follicles; n = 33) and C (four follicles; n = 58). The three groups were similar in age, day 3 FSH, total gonadotrophin dose, duration of stimulation, peak oestradiol concentration, oocyte yield, fertilization rate and the clinical pregnancy rate. However, group A had a significantly higher oestradiol concentration per follicle (P < 0.001). The clinical pregnancy rate/cycle in the three groups was comparable to our overall rate in the study period (25.5%). This paper suggests that poor responders with a normal day 3 FSH may still achieve a pregnancy rate similar to that of normal responders.  (+info)

A prospective, randomized, double-blind clinical trial to study the efficacy and efficiency of a fixed dose of recombinant follicle stimulating hormone (Puregon) in women undergoing ovarian stimulation. (7/1572)

A prospective, randomized, double-blind, multicentre (n = 5) study was conducted to compare the influence of either a 100 or 200 IU daily fixed-dose regimen of recombinant follicle stimulating hormone (FSH) on the number of oocytes retrieved and the total dose used in down-regulated women undergoing ovarian stimulation. Fertilization was done by intracytoplasmic sperm injection or conventional in-vitro fertilization. A total of 199 women were treated with FSH, 101 subjects with 100 IU and 98 subjects with 200 IU. In subjects of the 200 IU treatment group, significantly more oocytes were retrieved compared to the 100 IU group (10.6 versus 6.2 oocytes, P < 0.001). The total dose needed to develop at least three follicles with a diameter of > or = 17 mm was significantly lower in the 100 IU treatment group (1114 IU versus 1931 IU, P < 0.001). In the low-dose group, significantly lower serum concentrations of oestradiol, progesterone and FSH were observed at the day of human chorionic gonadotrophin administration. Although more cycle cancellations due to low response were seen in the 100 IU group (n = 24 versus n = 3), the clinical pregnancy rate per started cycle was similar (24.7% in the 100 IU group versus 23.3% in the 200 IU group). In the high-dose group, more side-effects, in particular more cases of ovarian hyperstimulation syndrome, were noted. It is concluded that compared to 200 IU, the use of a 100 IU fixed dose is less efficacious in terms of the number of oocytes retrieved, but more efficient as indicated by a lower total dose.  (+info)

Sperm treatment with extracellular ATP increases fertilization rates in in-vitro fertilization for male factor infertility. (8/1572)

Previous work from our laboratory has revealed that extracellular ATP is a rapid and potent activator of human sperm acrosome reaction and fertilizing ability. In the present study, we assessed the effects of in-vitro sperm incubation with ATP on fertilization and embryo development in couples undergoing in-vitro fertilization (IVF) for male factor infertility. Oocytes from 22 women undergoing ovulation induction were divided in two groups and inseminated in vitro either with selected spermatozoa from the corresponding partner suffering from male factor infertility pre-incubated with ATP (2.5 mM) for 1 h, or with spermatozoa incubated with 0.9% NaCl solution (control group). After insemination, fertilization was assessed by the presence of pronuclei and then by embryo cleavage. The fertilization rate in the group of oocytes inseminated with ATP-treated spermatozoa improved significantly with respect to the control group (65.7 versus 42.5%, P < 0.01). No significant differences were observed in embryo cleavage and embryo quality. Embryos from both treated and control groups were transferred together in 20 transfer procedures, and in two couples fertilization was not obtained. Nine pregnancies occurred: one biochemical, one miscarriage, and seven patients delivered 9 healthy babies. Two pregnancies were twin with an overall pregnancy rate of 40.9% per cycle and of 45% per transfer. In conclusion, the results of the present study demonstrate that, in humans, extracellular ATP induces a significant increase of sperm fertilizing potential, as these findings are a rationale for the use of ATP for in-vitro treatment of human spermatozoa during IVF.  (+info)

ovulation induction treatment,ovulation induction treatment India,ovulation induction,ovulation induction India,reasonable price ovulation induction treatment-Information provided by
INTRODUCTION: Mild ovarian stimulation has been conceived, proposed and implemented in clinical practice as a safer and cheaper alternative to conventional strategies of controlled ovarian hyperstimulation in preparation for in vitro fertilization (IVF). Our aim was to summarize the key evidence on this topic and explore its possible role as the standard treatment option for women undergoing IVF. MATERIALS AND METHODS: A short narrative review of the existing literature, with emphasis on mild ovarian stimulation clinical and cost effectiveness, as well as treatment limitations. RESULTS: Numerous studies highlight mild ovarian stimulations favorable characteristics with respect to oocyte/embryo quality, reduced patient risk, and ease of intervention. There is, however, a need for high-quality laboratory environment. Limitations regarding poor responders, older women, or those seeking ovarian stimulation for non-infertility indications should also be considered. Finally, outcomes on the cumulative
Definition of ovulation induction in the dictionary. Meaning of ovulation induction. What does ovulation induction mean? Information and translations of ovulation induction in the most comprehensive dictionary definitions resource on the web.
TY - JOUR. T1 - Luteal function following ovarian stimulation in rhesus monkeys for in vitro fertilization. T2 - Atypical response to human chorionic gonadotropin treatment simulating early pregnancy. AU - VandeVoort, C. A.. AU - Hess, D. L.. AU - Stouffer, R. L.. PY - 1988. Y1 - 1988. N2 - This study determined if corpora lutea of hyperstimulated cycles in rhesus monkeys could be rescued by the pregnancy signal, chorionic gonadotropin (CG), given at the typical time of implantation. At menses, female monkeys received human follicle-stimulating hormone (hFSH, 60 IU, days 1 to 6) followed by human menopausal gonadotropin (hMG, 60 IU hFSH/60 IU luteinizing hormone [hLH], days 7 to 9). On day 10, human chorionic gonadotropin (hCG) was given to mimic the LH surge. Nine days later, a regimen of daily increasing doses of hCG (15 to 360 IU twice a day) was initiated to simulate rescue of the corpus luteum in early pregnancy. Serum levels of progesterone (P) increased through day 5 of the luteal phase ...
All ovulation induction drugs work by either increasing the patients own FSH (oral meds including Clomid or Letrozole) or by providing exogenous (already made from an outside source) FSH (injectables like Gonal F, Puregon, Menopure/HMG). It is the injectable drugs that achieve superovulation. Injectables can also be used for a small percent of patients who are resistant to oral medications in order to achieve single ovulation (monofollicular development).. Careful monitoring and dose adjustment are mandatory for safe ovulation induction, especially when injectables are used. Proper timing of the ovulation trigger is mandatory for proper egg maturation, to deliver the sperm at the ideal time, or to time when to collect the eggs in cases of IVF treatment.. Proper monitoring and frequent dose adjustment with proper, timely communication are mandatory for safe and successful treatment.. Ovulation induction treatment is usually continued for 3-4 cycles.The success rate per cycle is in the range of ...
Zimt Conferences & Seminars Organizing and IVF Lite Foundation has come together to host the World Congress on Ovulation Induction & Ovarian Stimulation Protocols. Zimt Conferences & Seminars Organizing is a recent start-up in Dubai. Zimt Conferences & Seminars Organizing which specialises in Medical Meetings, CMEs & Exhibitions has garnered exclusive rights to host the World Congress on Ovulation Induction & Ovarian Stimulation Protocols ( for a tenure of 11 years annually at exclusive beach resorts in Asia/Africa.
A four-day World Congress on Ovulation Induction & Ovarian Stimulation Protocols was held in Jaipur from August 7 to 10, informed Dr. Vandana Narula via facebook posting and pictures.
How Much Does Ovulation Induction Cost in Mumbai 2021 - Ovulation induction cost in Mumbai is INR 15k (15,000), rest of all depends upon the type of ovulation medication selected by the female
Mitochondria are the most abundant organelles within the oocyte and are fundamental for energy metabolism, spindle formation and chromosome segregation. Therefore it is likely that a reduction in mitochondria number or function may explain the decreased quality, developmental potential and increased frequency of chromosomal non-disjunction in oocytes from older women, especially when coupled with IVF stimulation regimens. The aim of this study was to delineate, using a novel bovine model of human IVF stimulation, the effects of ovarian stimulation regimens and maternal age on mitochondrial DNA copy number and function of the cumulus-oocyte-complex. Seven young (4 years old) and five old (11 years old) cloned cows with an identical genetic background, and managed as one herd, were subjected to repeated rounds of ovarian stimulation; four natural (hCG), three mild (FSH and hCG) and two heavy stimulated (GnRH agonist, FSH and hCG) cycles. Individual cumulus-oocyte-complexes were collected. The ...
The study will be a randomized controlled trial of adult women with primary and secondary infertility seen at the University of Michigan Health System undergoing ovulation induction (OI) with letrozole as part of their standard clinical care. Patients who are undergoing OI with letrozole as per standard clinical care will be randomized to urinary luteinizing hormone (LH) ovulation predictor kit use versus mid-cycle ultrasound with administration of hCG when appropriate for timing of intercourse or intrauterine insemination. Patients who have been prescribed letrozole as per routine clinical care will be approached to determine willingness to participate in this study. Study period involves up to three ovulation induction cycles or until pregnancy occurs ...
Ovulation Induction (OI) treatment is exactly what it says it is - using simple fertility drugs, we can help stimulate your ovulation. Our experts offer ovulation induction in London, UK.
Ovulation Induction OI Definition - Ovulation induction (OI) refers to a procedure that increases the production and or release of fully matured eggs...
Are you looking for best Ovulation Induction/ Controlled Ovarian Stimulation treatment center in Chennai, India. Contact us to fix an appointment.
Starting ovarian stimulation on days 2 or 15 of the menstrual cycle yielded similar oocyte numbers in same oocyte donors with encouraging pregnancy rates in recipients of the vitrified oocytes.
released. There is approximately 25% of infertile women who have problems with ovulation. By helping these women to ovulate regularly, it increases their chances of pregnancy. These medications are called fertility drugs and may also improve the endometrium (lining of the womb or uterus) which is required for pregnancy.. Ovulation induction can help women who have irregular periods as they are likely to have ovulatory dysfunction by helping them to have regular ovulation. Some ovulation problems include: polycystic ovarian syndrome (PCOS) - a hormonal condition which causes the eggs to not be released, ovaries that do not respond to hormones that help the maturation and release of the egg (luteinizing hormone (LH) and follicle stimulating hormone (FSH)), thyroid problems, eating disorders, extreme weight gain and weight loss.. Before fertility drugs are given to patients, doctors often use a hysterosalpingogram (HSG) to make sure that the fallopian tubes (tubes for the fertilized egg to travel ...
The aim of this study is to assess the oocyte yield of infertile women with suspected or known poor ovarian reserve (POR) undergoing a GnRH antagonist protocol for IVF with Merional® starting either with a low (150 IU) or a high dose (450 IU) and adding 100mg of CC (Serophene®) in the early follicular phase of the stimulation (day 3 to 7). To date no RCT has been conducted to compare the reproductive outcome of patients with POR as defined by the ESHRE Bologna criteria after controlled ovarian hyperstimulation with HMG in an GnRH antagonist protocol using low doses versus high doses of HMG and adding CC versus placebo. We hypothesize that adding 100 mg of CC on day 3-7 to a HMG antagonist protocol will lead to an additional increment of endogenous GT thus increasing the oocytes yield after controlled ovarian stimulation due to higher endogenous gonadotropin secretion ...
One of the indications of infertility is irregular menstrual cycles which makes it hard to know when or if ovulation is occurring. In this case, ovulation induction maybe recommended using medication to allow an egg to mature and ovulate, giving them better odds in achieving a conception through timed intercourse of artificial insemination.. The most commonly used ovulation induction medication used in ALPHA IVF is clomiphene citrate (oral medication) or daily injections of Follicle Stimulating Hormone (FSH).. Indications for ovulation induction. Ovulation induction may be the best choice if you:. ...
Ovulation induction is the action of bringing about ovulation through oral (Letrozole, Clomiphene Citrate, Tamoxifen) or injectable (gonadotropins) hormonal medication.
Ovulation medications can stimulate more than one egg to be released which increases the possibility of having twins or multiple births. At the Center for Infertility and Reproductive Surgery we strive to maximize pregnancy rates while minimizing the number of high order pregnancies established, since these pregnancies involve risks to both the mother and the fetuses.. When ovulation induction is successful, pregnancy rates per cycle are close to those of normally ovulating women in a comparable age group. Learn more about our success rates.. ...
The Pregnancy Outcomes Comparison on Natural or Controlled Ovarian Stimulation Cycles in Intrauterine Insemination Treatment: An Analysis of 8,893 Cycles Objective: To e..
Ovulation difficulties preventing pregnancy? Ovulation induction San Diego uses meds to stimulate ovaries and produce/release mature eggs for fertilization.
Aim: Outside of Japan, recombinant-human chorionic gonadotropin (r-hCG) is widely used for the induction of final follicular maturation and early luteinization in women undergoing ovulation induction; whereas in Japan, urine-derived hCG (u-hCG) is predominantly used. The primary objective of this study was to demonstrate the non-inferiority of r-hCG to u-hCG for ovulation induction, as assessed by the ovulation rate. Methods: This was an open-label, parallel-group, randomized, multicenter, phase III trial in Japanese women with anovulation or oligo-ovulation secondary to hypothalamic-pituitary dysfunction or polycystic ovary syndrome, undergoing ovulation induction with recombinant-human follicle-stimulating hormone ...
According to the revised terminology of the International Society for Mild Approaches in Assisted Reproduction (ISMAAR), mild stimulation protocols include a) the natural cycle, b) modified natural cycle, and c) mild stimulation.. Mild ovarian stimulation involves the administration of a low dose of FSH (up to 150 IU/day) for a shorter duration, aiming at the development of fewer follicles and the collection of up to 7 oocytes. Mild stimulation protocols mainly use GnRH antagonists.. However, the use of mild stimulation protocols remains low, mainly because they require a sound knowledge of the GnRH antagonist protocol and optimal laboratory conditions.. At Eugonia we successfully use mild protocols for ovarian stimulation with specific criteria, taking into account the history of each individual couple.. ...
What does IUI cost? How about ovulation induction? In our characteristic spirit of honesty, we provide actual dollar figures, not just vague generalities.
Ovulation induction is a treatment for anovulation, an infertility condition in which follicles in a womans ovary do not mature and release eggs.
Patricia Fauque, M.D., Ph.D.. Volume 99, Issue 3, Pages 616-623, 1 March 2013. Abstract:. This systematic review reports the effects of ovulation induction on epigenetic control. Studies mainly done in the mouse model highlight that hormonal treatments may be per se prejudicial to the epigenetic reprogramming of the gametes as well as of the early embryos. Moreover, hormonal protocols used in assisted reproduction may also modify the physiological environment of the uterus potentially linked to endometrial epigenetic disturbances. Nowadays, the little data available in humans does not allow us to independently determine the impact of the womans age, infertility problems, protocols and doses of hormonal treatments on processes including genomic imprinting, and therefore emphasizes the need for further studies on humans.. ...
What is ovulation induction? Could it be the answer to your infertility struggles? Learn more from a world-class fertility clinic in Tucson, AZ.
I have been taking ovulation induction drugs for 5 cycles now and am not sure whether it is worth continuing as I seem - Answered by a verified OB GYN Doctor
Ovarian stimulation plays a pivotal role in assisted reproductive therapies, to increase the number of embryos available for treatment; however, there is no clear consensus from meta-analyses in the literature which, if any, of the preparations in use are superior in terms of clinical outcomes. The aim of this thesis was to examine the effect of common human gonadotrophin preparations with different half lives and LH activity (hMG, rFSH and Pergoveris) on embryo quality and resulting offspring, compared to non- stimulated negative controls and positive PMSG treated controls, using the mouse model. The studies in this thesis indicated that an LH ceiling threshold is evident during folliculogenesis, where the use of long acting LH preparations resulted in higher numbers of fragmented oocytes, absent of cumulus cells (P,0.001), reduced expression of the pro and anti-angiogenic factors, MYHII and PEDF in cumulus cells (P,0.05), increased embryonic developmental arrest (P,0.001) and perturbed IGF2 ...
The initial use of drugs for ovulatory problems was inducing ovulation in women who did not ovulate, according to the UCSF Medical Center. They were typically patients who experienced menstrual cycles that were irregular. The objective of treatment was to manufacture one healthy egg. A second use was boosting the number of eggs that matured during the womans cycle in order to raise the odds that she would conceive.. Since the 1990s, physicians have also been treating women who do ovulate with medications to increase fertility. Many of these patients have unexplained infertility that could in fact be due to defects in their ovulatory process. The objective of therapy is the production of more than one egg to increase the pregnancy rate.. Before deciding which fertility treatment option is the best for the patient, specialists perform a thorough fertility evaluation to determine the specific reason why conception has not occurred. They treat any hormonal disorders before beginning induction with ...
Women are born with a limited reserve of oocytes, and this supply diminishes continuously during their life reaching critical numbers by age 40. A fetal ovary contains about 6-7 million oocytes by the 20th week of gestation. From mid-gestation onward there is a relentless and irreversible loss of oocytes by a process known as atresia. At birth, girls have lost about 80% of their initial reserve of oocytes, only one to two million are present in the ovaries at this time. The number of oocytes decreases even further to about 300, 000 by the onset of puberty. Of these oocytes, only 400-500 will ovulate in the course of a reproductive life span, less than 1% of the total number of initial oocytes. When the women are about 50 years old, the number of oocytes is exhausted and they enter the menopause.. In the fetal ovary, soon after they are formed, the oocytes are surrounded by a layer of supporting cells and enter a resting state where they remain until they resume growth. There are intra- and ...
Tablets or hormone injections can stimulate ovulation. Youll be carefully monitored using blood tests and ultrasound. Call 1800 628 533.
Tablets or hormone injections can stimulate ovulation. Youll be carefully monitored using blood tests and ultrasound. Call 1800 628 533.
Ovulation and Conception Calculator: The release of a mature egg from a womans ovary is defined as ovulation. It is usually quite regular and generally occurs around the 14th day of a normal 28-day menstrual cycle. Knowing the time of ovulation is usually a good tool to ensure successful conception since it is the most fertile time for a woman. Maximum fertility is during 24 hours before and after ovulation. An ovulation and conception Calculater is designed to be a prediction tool for this time based on the womans cycle.. If your cycle is irregular on occasion, you can still use the ovulation and conception Caculator. However, if it varies frequently between 21 to 35 days, or if you completely miss periods, your cycle is too irregular. Constantly irregular periods may mean that you are ovulating irregularly, so the calculator wont work and should not be used as a fertility predictor. If your cycle is consistently irregular, do not use the Calcualtor. Also, it is important to note that ...
Arcuate uterus and pregnancy loss: which is the cause and which is the outcome? 2014: 3rd World Congress on Ovulation Induction & Ovarian Stimulation Protocols : TSRM 2015: Human Fertility değerlendirme aşamasında
RSMC in San Diego is a physician-managed fertility center that ensures their patients are well informed. Find out more about common fertility medications.
Ovulation induction cycles are usually controlled by one of the drugs Lupron, Cetrotide, or Ganirelix. Ovulation cannot occur when a patient is receiving one of these products because they all prevent the LH surge, albeit by different mechanisms.. Lupron essentially blocks the production of estrogen by the pituitary which is why it is also an effective treatment for endometriosis. Ganirelix and Cetrotide act more rapidly than Lupron to block FSH/LH production by the pituitary. Ganirelix and Cetrotide can be given in lower doses for shorter periods of time.. An IVF cycle requires that mature eggs develop so that they can be retrieved and fertilized. Lupron/Ganirelix prevents ovulation of the eggs before they can be retrieved. If they are ovulated prematurely, the IVF cycle will be lost. This is one reason why careful cycle monitoring, precise manipulation of the various fertility drugs and physician experience are critical to IVF success. Once the eggs are mature, an injection of hCG is given ...
Principal Investigator:AONO Toshihiro, Project Period (FY):1998 - 2000, Research Category:Grant-in-Aid for Scientific Research (B)., Section:展開研究, Research Field:Obstetrics and gynecology
ES] El objetivo general fue la caracterización reproductiva de las hembras de una línea de conejo seleccionada por velocidad de crecimiento y el efecto de distintas estrategias nutricionales (ad libitum y restringidas), con la finalidad de mejorar el rendimiento reproductivo. En el capítulo 1 se evaluó la influencia de los genotipos materno y embrionario en la supervivencia prenatal y crecimiento fetal, entre las hembras de esta línea y una línea maternal. La supervivencia prenatal, peso fetal y el peso de la placenta resultaron afectados por los genotipos tanto embrionario como materno, pero no se detectaron diferencias sobre la placenta fetal a nivel del transcriptoma ni en los niveles de progesterona e IGF-I. Por lo tanto, se puede concluir que en éstas tanto el genotipo embrionario como el materno son factores clave en su rendimiento reproductivo.El objetivo del capítulo 2 fue explorar las causas de los fallos reproductivos en estas hembras. Los resultados mostraron que las hembras ...
My friend had a high BMI and unfortunately wasnt given clomid or any other medication until she got her BMI down, she also has PCOS. I dont think the hospital will discharge you, but maybe they could refer you to a dietician for some help and support? In terms of going private, I wouldnt at this stage if I were you, you have an option open to you and although loosing weight is hard that may be the thing that helps you ovulate, even with out the clomid. Clomid will not do anything unless you get your weight down, it will just make you feel crap - I would wait and take it when you know it has a good chance of working, after all they only recommend taking it for so many months. The happy story is my friend got pregnant and has a beautiful girl, but she thinks it was more to do with the weight loss than the drugs ...
Ovarian Stimulation with Fertility Medication used in the early stage of treatment to produce multiple mature eggs & increases the probability of pregnancy
Dr. Yuliya Blazhko, fertility specialist, is discussing how repeated Controlled Ovarian Stimulation can influence the number of oocytes obtained
Antagonist Protocol Definition - An antagonist protocol is a process used during in vitro fertilization (IVF) to prevent premature ovulation. It uses...
Ovulation - MedHelps Ovulation Center for Information, Symptoms, Resources, Treatments and Tools for Ovulation. Find Ovulation information, treatments for Ovulation and Ovulation symptoms.
3. Next step- For insurance reasons, we cannot move on to IVF immediately if this cycle does not succeed. My carrier requires two cycles of FSH/OI (ovulation induction)/IUI before theyll authorize an IVF cycle, regardless of my age. My RE prefers to do an injectibles/IUI cycle before moving on to IVF anyhow because it gives her the opportunity to see how a patient responds to the drugs before getting into an IVF cycle... a rehearsal, more or less, before the big show. If I am not pregnant by 3/24, well do FSH/OI/IUIs in April and May. If Im still not pregnant by Memorial Day, well take the month of June off from TTC (like thats possible) in preparation for a July IVF. Ill be 42 before my first child is born, if thats the case. Im keeping my focus on NOW. I dont want to think about next year already ...
Secondary unexplained infertility led me to IVF, giving me my IVF baby. Now, I am sharing my IVF Process and IVF Medications for the antagonist protocol.
EN] Selection for growth rate is negatively related with reproductive fitness. The aim of this work was to analyse the causes of fertility failure in rabbit does selected for growth rate and characterised for reproductive deficiencies (line R). In the experiment, 82 does were divided into 2 groups: naturally mated (NM) and artificially inseminated (AI), to relate luteinizing hormone (LH) concentration with ovulation induction and pregnancy rate by laparoscopic determination. Additionally, in 38 of these females ovulation rate and metabolites determination (leptin, NEFA, BOHB and glucose) were analysed and perirenal fat thickness measurement and live body weight (LBW) determined. The results showed that all ovulated does (both NM and AI) presented higher concentrations of LH than non-ovulated females. In addition, non-ovulated females showed high levels of leptin and BOHB, as well as LBW. Females from line R have an inherit reduced fertility due to ovulation failure as a consequence of a ...
This in simplest terms refers to the conglomeration of symptoms and signs that result from overstimulated and enlarged ovaries, more often than not; due to fertility treatment.. Thus, it is a complication of controlled ovarian hyperstimulation, one of the key steps in in-vitro fertilization. It is also potentially life threatening.. It is somewhat rare, and thus, the overall incidence across the various degrees of severity is at most 6%.. Ovarian hyperstimulation syndrome(OHSS) can be classified as early or late. It is early when it occurs within eight days of giving the human chorionic gonadotrophin (HCG) injection trigger for ovulation and when it occurs after eight days it is termed ovarian hyperstimulation.. Early ovarian hyperstimulation is usually caused by fertility treatment, that is the administration of human chorionic gonadotrophin (HCG) while the late ovarian hyperstimulation is due to the human chorionic gonadotrophin released by the pregnancy.. The underlying pathway by which over ...
TY - JOUR. T1 - Does ovulation induction affect the pregnancy rate after laparoscopic treatment of endometriosis?. AU - Karabacak, Onur. AU - Kambic, Robert. AU - Gursoy, Rifat. AU - Ozeren, Semih. PY - 1999/1. Y1 - 1999/1. N2 - Objective - To determine the effectiveness of ovulation induction after laparoscopic treatment of endometriosis in an infertile population. Design - An observational prospective study in which infertility cases were treated with laparoscopic surgery was followed up (mean 11 months), either by treatment (ovulation induction) or no further treatment (expectant management) and the outcomes recorded. In both groups pregnancies were compared by Coxs regression survival model. Setting - Gazi University Hospital, Department of Obstetric and Gynecology, Ankara, Turkey. Patients - Infertile women with different stages of endometriosis who were treated by laparoscopic surgery, with a mean duration of infertility of 80.7 (± 50 [SD]) months. Interventions - Patients were treated ...
It is an iatrogenic complication of ovulation induction with exogenous gonadotropins. This disorder also occasionally can be observed in clomiphene-induced cycles. Risk factors for ovarian hyperstimulation syndrome include young age, low body weight, polycystic ovary syndrome, higher doses of gonadotropins, and previous episodes of hyperstimulation. Risk increases with serum estradiol levels and the number of developing ovarian follicles and when supplemental doses of hCG are administered after ovulation for luteal-phase support. Ovarian hyperstimulation syndrome has a broad pathophysiologic spectrum ranging from mild illness to severe disease. It has traditionally been classified as mild, moderate, or severe. Mild illness is characterized by ovarian enlargement, lower abdominal discomfort, and mild nausea and vomiting, diarrhea, and abdominal distention, and occurs in up to one-third of super-ovulation cycles. In general only oral analgesics and counseling to alert affected women to the signs ...
In addition to being nearly drug-free, it is also less expensive than standard IVF. Other benefits include:. • No risk of ovarian hyperstimulation syndrome: When taking fertility drugs to increase their egg production for IVF, some women experience this unpleasant condition. Symptoms of ovarian hyperstimulation syndrome include vomiting, diarrhea, pain near the ovaries, dark urine, decreased urination, rapid weight gain and shortness of breath.. • Less monitoring: Standard IVF requires many regularly scheduled office visits for blood tests and ultrasounds. Natural cycle IVF still requires some monitoring, but far less.. • Ovarian hyperstimulation isnt needed: Some women, for religious or other reasons, dont want to produce excess eggs that may later be discarded. Since natural cycle IVF only uses naturally produced eggs, this isnt a factor. Natural cycle IVF can be less expensive, less time-consuming and less complicated than standard IVF. If you want to know if natural cycle IVF is a ...
Comparison of long versus flexible antagonist protocol Our study is the largest one internationally. It is a randomized prospective study that compares long with flexible GnRH antagonist protocol.. The results show that pregnancy rates are similar in both protocols and there is also a significant reduction (by 20%) of severe ovarian hyperstimulation syndrome when the antagonist protocol is used.. The antagonist protocol is suggested as a protocol of choice for women with polycystic ovaries. The conclusions of this study are adopted by independent editors of international organizations (Faculty of 1000 Medicine) and are honorary selected in Editors choice by Professor Andre Van Steirteghem, who is the editor of scientific journal Human Reproduction.. The flattering comment that the suggested protocol can change the routine clinical practice refers to the finding that the flexible antagonist protocol is the safest protocol in women with polycystic ovaries without reducing their pregnancy ...
STUDY QUESTION: Does administration of corifollitropin alfa followed by highly purified (hp) HMG result in higher ongoing pregnancy rates compared with daily recombinant FSH (rFSH) in young poor responders? SUMMARY ANSWER: Corifollitropin alfa followed by hp-HMG does not increase ongoing pregnancy rates compared with rFSH in young poor responders, although more supernumerary cryopreserved embryos were obtained with corifollitropin alfa and hp-HMG. WHAT IS KNOWN ALREADY: Poor ovarian response remains one of the main therapeutic challenges in women undergoing ovarian stimulation, given that very low live birth rates of 6% have been reported in this particular group of infertile patients ...
Artificial insemination (AI) has been developed in multiple felid species as a tool for retaining gene diversity in threatened or endangered populations. Yet, pregnancy success remains low (, 5%) following AI in most felids, particularly in species that spontaneously ovulate. This failure has been attributed to variable ovarian status at the time of insemination and adverse residual effects caused by exogenous gonadotropins used to induce ovulation. Using the domestic cat as a research model, a new AI regimen that incorporated short-term ovarian suppression with oral progestin (altrenogest; ALT) before ovulation induction was investigated. The hypothesis was that oral progestin priming would prevent spontaneous ovulation, improve ovarian responsiveness to exogenous gonadotropins and mitigate adverse effects caused by persistent gonadotropin actions. Specific objectives were to: (1) increase fundamental understanding of the mechanisms controlling ovarian function; and (2) characterize how oral ...
TY - JOUR. T1 - A high ovarian response does not compromise the chance of pregnancy.. AU - Fatemi, Mousavi. AU - Doody, K. AU - Witjes, Han. AU - Mannaerts, B.. PY - 2011/7. Y1 - 2011/7. N2 - Introduction: Recently it has been suggested that the use of traditional controlled ovarian stimulation (COS) regimens may negatively affect embryo quality and implantation rates and further studies would be required to assess the impact of mild vs conventional stimulation in relation to oocyte/embryo chromosomal competence as well as endometrial receptivity.1 One aspect of this complex question may be analyzed by comparing the clinical outcome of low, normal, and high responders to a fixed treatment protocol of either corifollitropin alfa or recombinant follicle-stimulating hormone (rFSH), in a gonadotropin-releasing hormone (GnRH) antagonist protocol. The current subset analysis evaluates the relationship between the ovarian response to COS and ongoing pregnancy rates. Material and Methods: In a large, ...
Information about the open-access article Predicting and preventing ovarian hyperstimulation syndrome (OHSS): the need for individualized not standardized treatment in DOAJ. DOAJ is an online directory that indexes and provides access to quality open access, peer-reviewed journals.
Ovarian hyperstimulation syndrome may occur after using injectable hormone medications during in vitro fertilization (IVF), a treatment for infertility. Injectable fertility medications stimulate the development of eggs in the ovaries, but it can be difficult to tell exactly how much medication you might need.
Luteal faz ovarian stimülasyon standard regimens of ovarian stimulation are started during the early follicular phase of the menstrual cycle. One of the disadvantages of follicular-phase ovarian stimulation is that with the development of multiple follicles stimulated by exogenous gonadotropin, a premature LH surge is sometimes elicited. This is due to the positive feedback of high E2 on the pituitary and results in premature luteinization and suboptimal oocyte quality. Therefore, GnRH analog cotreatment is believed to be necessary to prevent the premature LH surge that occurs in the current practices, but this regimen makes the stimulation complex (7). Another detriment of ovarian stimulation is the serious complications caused by ovarian hyperstimulation syndrome (OHSS), a rare but potentially life-threatening condition. Few studies consider the possibility of performing ovarian stimulation during the luteal phase of the menstrual cycle except for a small number of case reports on cancer patients (8
Current recommended 1st line treatment for ovulation induction remains the usage of clomiphene and patients should be informed that there is an increased risk of multiple pregnancies with ovulation induction using clomiphene. (Grade A, Level 1+ evidence). Recommended 2nd line intervention for subfertility in women with PCOS is either exogenous gonadotrophins or laparoscopic ovarian surgery. (Grade D, Level 4 evidence) Recommended 3rd line intervention for subfertility in women with PCOS is in vitro fertilization (IVF). (Grade C, Level 2+ evidence) The routine use of metformin in ovulation induction is not recommended as monotherapy or in combination with clomiphene. (Grade D, Level 3). On the other hand, the combined use of metformin and clomiphene is recommended for women with clomiphene resistance especially if they are obese (BMI , 27.5). (Grade A, Level 1+) In women who have been diagnosed with PCOS prior to pregnancy, especially those requiring ovulation inductions for conception, they ...
To compare the efficacy of coasting to prevent ovarian hyperstimulation syndrome (OHSS) with i.v. albumin and to determine if different timing of gonadotropin coasting would affect the IVF outcomes.Retrospective study.University hospital-based IVF program.One hundred sixty-two women undergoing IVF treatment cycles who were considered to be at high risk for developing OHSS.Gonadotropin administration was withheld in 60 patients: either coasting occurred before follicular maturation (early coasting subset, n = 28) or follicular maturity was attained before coasting (late coasting subset, n = 32). Outcomes were compared in 102 patients at risk for OHSS who received i.v. albumin on the day of oocyte retrieval.Incidence of OHSS and outcome parameters.Although the fertilization rates and the incidence of OHSS did not differ significantly between the coasting and i.v. albumin groups, the mean number of oocytes retrieved, the pregnancy rates, and implantation rates were significantly lower in the ...
Dr. Geoffrey Sher established the first private IVF Center in the US in 1982. For over 30 years he has been advocate for womens reproductive health concerns while trailblazing medical breakthroughs.
article{3bac4e34-79d1-4847-855e-3a895175d0af, abstract = {Background. To evaluate the relationship between age and poor ovarian response to pregnancy and cancellation rate after IVF stimulation. Methods. Poor ovarian response was defined as <= 5 follicles at ovum pick up (OPU). Out of 1,706 consecutive OPUs performed during 2003/2004, 290 poor responders were identified. This cohort of poor responders was divided into two groups, older and younger, with a cut-off at the median age of 37 years. The pregnancy and cancellation rates after OPU were analysed. Results. Women aged > 37 years, who were poor responders, had a significantly lower pregnancy rate per OPU (3.0%) compared to normal to high responders in the same age group (22.1%, p < 0.05). Also, 43.6% of women > 37 years, who were classified as poor responders, did not receive an embryo transfer ( ET), compared to 13.2% of normal to high responders in this age group ( p < 0.05). Poor responders who were 5/37 years had a ...
Dr. Geoffrey Sher established the first private IVF Center in the US in 1982. For over 30 years he has been advocate for womens reproductive health concerns while trailblazing medical breakthroughs.
The stimulation of the ovary by fertility medication is desired and aims at increasing the number of eggs per cycle thereby increasing the chances of pregnancy.. Ovulation induction allows an egg to mature and be released by the ovary. Then follicular monitoring with blood tests and ultrasound, to confirm the best time to conceive.. Once the optimum size of follicles is achieved, medication (Inj hCG) is advised to trigger the release after maturation of egg (ovulation) from the ovarian follicle. This is the fertile period that is to be consumed naturally by timed intercourse or treatments are performed in this fertile period.. ...
Embryo competence depends on oocyte quality, which is affected by different factors, including the treatment modality [12, 13]. We do not know the exact effect of the dosages and types of drugs on oocytes in IVF. Therefore, it was suggested that mild stimulation protocols and natural cycles would reduce aneuploidy rates and increase embryo quality [12]. However, every step during ovulation induction could affect the oocytes and subsequent embryo development.. Triggering oocyte maturation is the last important step of ovulation induction. For a long time, hCG has been used as a triggering agent because of its homology with LH and extended half-life. Although the extended half-life of this molecule might be advantageous for luteal support, its effect on oocyte maturation is not clear and hCG-mediated LH activity differs from natural cycles. Recently, GnRH agonists have been used as the triggering agent, especially in patients at a high risk of OHSS in GnRH antagonist cycles. The GnRHa displaces ...
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84.7%, 73.3% and 88.7%, while the conception rates were 24%, 40% and 20% for the anti-estrogen, bromocriptine and HMG groups, respectively. Ultrasonography was used for timing of HCG administration in 80% of anti-estrogen group and all HMG stimulated cycles with preovulatory follicular diameter >18 mm which followed by subsequent ovulation in 96% and 100%, respectively. Cumulus oophorus was visualized in 20 cycles [8.5% of ovulatory cycles] . In 18 of these cycles, ovulation was diagnosed in the subsequent day after cumulus oophorus appearance which when visualized could be used as a predictor of ovulation. Ovulatory dysfunctions were detected ultrasonographically in 48 cycles. Twenty-seven cycles showed no follicular activity or follicular atresia, eight cycles showed follicular cyst formation, four cycles showed LUF which correlated with laparoscopy findings and P production. Mild ovarian hyperstimulation was diagnosed in six cycles, two in clomiphene citrate stimulated cycles and four in HMG ...
Methods and apparatus for testing of the efficacy of therapeutic stimulation of pelvic nerves or musculature to alleviate one of incontinence or sexual dysfunction are disclosed. A therapy delivery device is operable in a therapy delivery mode and a test mode and an evoked response detector is employed in the test mode to detect the evoked response to applied test stimuli. The test stimuli parameters of the test stimulation regimen are adjusted prior to delivery of each test stimulation regimen, and the evoked responses to the applied test stimulation regimens are compared to ascertain an optimal test stimulation regimen. The therapy stimulation regimen parameters are selected as a function of the test electrical stimulation parameters causing the optimal evoked response.
Ovulation induction is the use of hormonal medications to stimulate production & release of eggs for fertilization in women having trouble getting pregnant.
Ovulation induction is a fertility procedure in Australia and New Zealand. Learn about the journey & the regulations. Get in touch with the Fertility Society
These tests will identify the vast majority of poor responders before they get to an IVF attempt. Identifying the problem in advance allows us an opportunity to do something to improve the response (and the outcome) with the first IVF attempt.. The definition of a poor responder is variable. Regardless of the definition one uses, the basic idea is that poor responders do not respond well to the IVF ovarian stimulation protocol by making a good number of mature follicles. Less mature follicles means less eggs retrieved which results in lower numbers of embryos and less chance to have one that is a marathon runner (baby).. For example, women under 35 years old give an average of 12 eggs with IVF. However, poor responders would only produce about 1 to 6 eggs. The chances for success with IVF are very much dependent on two variables - the quantity and the quality of the eggs.. Therefore, if we could come up with a treatment that would help the poor responders to give either more eggs or better ...
Buy HMG (Human menopausal gonadotropins) injections online from Our shop. We guanrantee the delivery of HMG. HMG (Human menopausal gonadotropins) is a hormonally active medication for the treatment of fertility disturbances.
Conclusion: This approach is both simple and effective and it may prove to be an attractive alternative to the standard GnRH agonist long protocol.. Key words: friendly IVF, clomiphene citrate, ICSI, male infertility. As part of the complex physiological patterns of the menstrual cycle in humans, it has been demonstrated that during the first days of the follicular phase of the cycle, early antral follicles exhibit dissimilar sizes, ranging from 2 to 8 mm in diameter (1). This can partly be explained by the inconsistent sensitivity to follicle stimulation hormone (FSH) by the developing oocytes during follicular development (2, 3). This natural phenomenon involves the exposure of early antral follicles to gradient FSH levels during the late luteal phase. During the last days of the menstrual cycle (i.e. late luteal follicular phase transition) paralleling the corpus luteum demise, FSH levels increase progressively to preserve antral follicles from atresia, and ensure their subsequent growth (4). ...
Since 2008, there have been different results in a limited number of studies on single-dose CFA administration. In 2008, Devroey et al.(10) wrote the first study about CFA. The authors suggested that a single injection of corifollitropin alfa induced a dose-related increase in multifollicular development and in the number of retrieved oocytes(11). Devroey et al.(10) postulated that CFA was a novel and effective treatment option for potential normal-responder patients undergoing ovarian stimulation with GnRH antagonist co-treatment for IVF resulting in ongoing pregnancy rates equal to that achieved with daily rFSH. Mahmoud Youssef et al.(12) published a meta-analysis in 2012. They included four randomized trials involving 2326 women. There was no evidence of a statistically significant difference in ongoing pregnancy rates for CFA versus rFSH(12). Boostanfar et al.(13) designed a large comparative randomized double-blind trial that confirmed the non-inferiority of pregnancy rates for CFA compared ...
Controlled ovarian hyperstimulation (COH) which combines GnRH antagonist co-treatment and GnRH-agonist (GnRHa) trigger has become a common tool aiming to eliminate severe early OHSS and to support the concept of an OHSS-free clinic. However, due to the reported significantly reduced clinical, efforts have been made to improve reproductive outcome. One of the suggested optional strategies aiming to improve outcome was the addition of low-dose (1500 IU) HCG bolus, administered, concomitant, 35 h or 5 days after the triggering bolus of GnRHa. All these regimens were demonstrated to rescue the luteal phase, resulting in improved reproductive outcome in patients at risk to develop severe OHSS, compared to GnRHa trigger alone, however, with the questionable ability to eliminate severe OHSS. Moreover, following the observations demonstrating comparable or even better oocyte\embryos quality following GnRHa, compared to hCG trigger, and the different effects of LH and hCG on the downstream signaling of the LH
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addition, once the pregnancy is achieved, similar In most cases, when submitted to COS protocols, abortion rates were observed in PR patients when patients with a low number of antral follicles often receive a higher initial dose of gonadotrophins. In During follicular development, the vast majority of addition, when the standard dose of gonadotrophins follicles will go to atresia either by apoptosis or fails to induce a proper multifollicular growth, the necrosis at some stage of development. The criteria expected clinical approach is to increase the dose for determining the number and selection of follicles (Surrey & Schoolcraft, 2000). As a result, the total which are removed from the pool become less dose of gonadotrophins is significantly higher in poor stringent with increasing age. Assuming that follicle atresia plays a role in determining the overall quality matched NRs stimulated during similar interval of of follicles which reach the final stage of develop- days. There is, however, ...
過去的傳統不孕症治療,最為人所詬病的便是通常需要注射大量的排卵針劑,不僅造成身體的負擔,也帶給不孕症患者心理上的龐大壓力。事實上,過多的排卵針劑刺激,除了易引發Ovarian hyperstimulation syndrome ...
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L. Pranathi Reddy, Y. Madhavi, Mohammed Ismail Khan.. Role of Sildenafil in ovulation induction A comparative study of outcomes with Sildenafil in ovulation induction cycles with Clomiphene Citrate.. IAIM, 2016; 3(12): 26-32.. Download PDF ...
Regardless of their age, between 20 and 25% or patients have poor ovarian response (POR) and to induce the growth of multiple follicles is a challenge and sometimes a frustrating problem, said Dr. Ubaldi. POR is one of the most debated aspects of assisted reproduction and there has been controversies surrounding the variety of methods used to treat POR and the lack of an objective and clear definition of term Poor Ovarian Response. In fact, poor responders have a reduced chance of getting pregnant. As a consequence ESHRE gathered its 11 Special Interest Groups from all aspects in the field of assisted reproduction to discuss the definition of POR. A consensus was reached during the campus symposium in Bologna in March 2010 and all agreed that maternal age (,40 years) had a relevant impact on POR. In the UK the number of women delivering after 40 years of age has increased two-fold in ten years and three-folds in the last twenty years. A similar trend was observed in Italy with 6% of babies ...
To induce the rupture of the follicle and improve progesterone production, the fertility specialist will administer a trigger injection. This is done when the follicle reaches maturity, which is determined by size of follicle on ultrasound and bloodwork for LH level surge. An egg is released 24-42 hours after the trigger shot is given, which is optimal time for intercourse or artificial insemination.. ...
TY - JOUR. T1 - Mono-ovulatory cycles. T2 - A key goal in profertility programmes. AU - Baird, D. T.. AU - Collins, J.. AU - Crosignani, P. G.. AU - Evers, J. L H. AU - Fanchin, R.. AU - Fauser, B. C.. AU - Filicori, M.. AU - Jacobs, H.. AU - Tarlatzis, B.. AU - Cohen, J.. AU - Diczfalusy, E.. AU - Diedrich, K.. AU - Fraser, L.. AU - Frigerio, G. C.. AU - Gianaroli, L.. AU - Harlin, J.. AU - Persson, J.. AU - Rojas-Rìos, A.. AU - Sunde, A.. AU - Van Steirteghem, A.. AU - Crosignani, Pier Giorgio. PY - 2003/5. Y1 - 2003/5. N2 - Mono-ovulatory cycles for women are optimal because singleton pregnancies have a better outcome than multiples. Multiple births began to increase in the 1950s after the first appearance of effective ovulation induction for the treatment of anovulation. Since the 1980s when ovulation induction and IVF were more broadly applied to the treatment of unexplained and persistent infertility, there has been an unprecedented rise in multiple births. Strategies to achieve ...
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This study compared the efficacy and tolerability of corifollitropin alfa and recombinant follicle stimulating hormone in women with ongoing pregnancies
A Second Dose of GnRHa in Combination with Luteal GnRH Antagonist May Eliminate Ovarian Hyperstimulation Syndrome in Women with =30 Follicles Measuring =11 mm in Diameter on Trigger Day and/or Pre-trigger Peak Estradiol Exceeding 10 000 pg/mL ...
Serum AMH levels gradually decrease during GnRH-antagonist protocol for IVF. This decrease starts at the beginning of the follicular phase and continues up to the day of hCG administration. These results underscore the important role that AMH plays in the process of folliculogenesis and dominant fol …
Detailed Clomiphene dosage information for adults. Includes dosages for Ovulation Induction; plus renal, liver and dialysis adjustments.
Ovarian hyperstimulation syndrome. Complication of assisted reproduction techniques, potentially serious and even fatal, characterized by vascular leakage
This medication may cause a condition known as ovarian hyperstimulation syndrome (OHSS). Rarely, serious OHSS causes fluid to suddenly build up in the stomach, chest, and heart area. This may occur during therapy or after treatment has been stopped. Get medical help right away if you develop any of the following side effects: severe pain/swelling in the lower abdomen (pelvic) area, sudden/rapid weight gain, nausea/vomiting, diarrhea, shortness of breath, change in the amount of urine, pain/redness/swelling of the legs, chest pain, fast/irregular heartbeat ...
HCG Injection After Ovulation Induction With Clomiphene Citrate at Medscape. By Peter Kovacs. Posted: 04/23/2004 ... In the presence of one or more mature ovarian follicles, ovulation can be triggered by the administration of HCG. As ovulation ... Ovulation Induction. Retrieved Mars 7, 2010 Talwar GP, Gupta JC, Rulli SB, Sharma RS, Nand KN, Bandivdekar AH, Atrey N, Singh P ... Because of its similarity to LH, hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone ...
van Wely M, Yding Andersen C, Bayram N, van der Veen F (2005). "Urofollitropin and ovulation induction". Treatments in ... Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and ...
Step by Step Ovulation Induction. Anshan Ltd, Kent, United Kingdom. ISBN 1-904798-96-9. Page 44. Follicle Stimulating Hormone ... antibodies generated in goats treated with eCG for the induction of ovulation modulate the luteinizing hormone and follicle- ... used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. For example, the so- ... Typically a single injection of 10,000 international units is used to induce ovulation. In men: Used to treat select cases of ...
Ghumman S (2006). Step by Step Ovulation Induction. Kent UK: Anshan. p. 134. ISBN 978-1-904798-96-5. Navot D, Rosenwaks Z, ... "Successful pregnancy in a 42-year-old woman with imminent ovarian failure following ovulation induction with ethinyl estradiol ... In the control group there were no ovulations. The patients ranged in age between 24 and 39 years with an average age of 32.7. ... Whereas nafarelin acetate in a nasal spray induces a short lived LH surge that is high enough to induce ovulation in large ...
23-. ISBN 978-1-351-78989-9. Deshpande H (12 February 2016). Practical Management of Ovulation Induction. JP Medical Ltd. pp. ... on induction of menstruation, inhibition of nidation, and termination of pregnancy in bonnet monkeys". Biology of Reproduction ...
Tanbo T, Mellembakken J, Bjercke S, Ring E, Åbyholm T, Fedorcsak P (October 2018). "Ovulation induction in polycystic ovary ... Sharpe A, Morley LC, Tang T, Norman RJ, Balen AH (December 2019). "Metformin for ovulation induction (excluding gonadotrophins ... for ovulation induction in infertile women with polycystic ovary syndrome". The Cochrane Database of Systematic Reviews. 2022 ( ... "Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline". Fertility ...
ISBN 978-0-443-04514-1. Josef Blankstein; Shlomo Mashiach; Bruno Lunenfeld (1 July 1986). Ovulation Induction and in Vitro ... medication which is used as a gonadotropin stimulant or ovulation inducer and in menopausal hormone therapy in women. It is ... effects on the hypothalamic-pituitary-gonadal axis and hence can increase sex hormone production and stimulate ovulation. ...
Greenblatt, R., & Mahesh, V. (1965). Induction of Ovulation with Clomiphene Citrate. In T. Schwartz, Yearbook of Endocrinology ... Induction of Ovulation with MRL/41. JAMA, 178, 101. Greenblatt, R., Mahesh, V., & Jungck, E., Roy S. (1963). Clomiphene Citrate ... Further Observations on Its Use in Induction of Ovulation in the Human and Its Mode of Action. Fertility and Sterility, 14, 575 ... His group's discovery in 1961 that clomiphene citrate could induce ovulation was a breakthrough in reproductive biology, and ...
The NSAI, letrozole is also used for ovulation induction in women with polycystic ovary syndrome (PCOS). Generally, clomiphene ... Holzer, Hananel; Casper, Robert; Tulandi, Togas (2006-02-01). "A new era in ovulation induction". Fertility and Sterility. 85 ( ... ISBN 3-7643-7199-4. Kar, Sujata (2013-04-01). "Current evidence supporting "letrozole" for ovulation induction". Journal of ... Letrozole seems to be just as effective as clomiphene citrate for ovulation and pregnancy rate as it has shown to be very ...
Kistner RW (December 1965). "Induction of ovulation with clomiphene citrate (clomid)". Obstet Gynecol Surv. 20 (6): 873-900. ... "Induction of ovulation with clomiphene citrate (clomid)" "Histological effects of progestins on hyperplasia and carcinoma in ...
1958, First report using pituitary FSH 1960, "An immunological pregnancy test" 1962, "Induction of ovulation with human ... Gemzell, C. A. (1962). "Induction of ovulation with human pituitary gonadotrophins". Fertility and Sterility. 13 (2): 153-68. ... Ovulation stimulation using FSH medication became the basis of modern infertility therapy such as IVF. First pregnancies were ... was the first to show that extracted gonadotropins containing FSH could be used as fertility medication to stimulate ovulation ...
Artificial induction of ovulation and in vitro fertilization-embryo replacement can also give rise to fraternal and identical ... "Increased Monozygotic Twinning Rate After Ovulation Induction". The Lancet. 329 (8544): 1236-1238. doi:10.1016/S0140-6736(87) ...
Weiss NS, Kostova E, Nahuis M, Mol BW, van der Veen F, van Wely M (January 2019). "Gonadotrophins for ovulation induction in ... However, ovulation induction remains an off-label indication, which affects use. Gonadotropins are protein hormones that ... Final maturation induction of follicles, also triggering a predictable time of ovulation. Either gonadotropin-releasing hormone ... The main techniques involving fertility medication in females are: Ovulation induction, with the aim of producing one or two ...
Gautam Allahbadia (29 February 2016). Manual of Ovulation Induction & Ovarian Stimulation Protocols. JP Medical Ltd. pp. 94-. ...
Kovacs, P (2004). "HCG injection after ovulation induction with clomiphene citrate". Medscape. Retrieved 2011-08-01. Oyawoye OA ... Injection of hCG as a trigger for ovulation confers a risk of ovarian hyperstimulation syndrome, especially in women with ... When the ovarian follicles have reached a certain degree of development, induction of final oocyte maturation is performed, ...
Ovulation Induction: using substances known as ovulation inductors. Semen capacitation: wash and centrifugation, swim-up, or ... To increase the chance of success, the woman's menstrual cycle is closely observed, often using ovulation kits, ultrasounds or ... there is no control of how many oocytes are at the same time when stimulating ovulation. For that reason, it is necessary to ... and viability of the male's sperm and the success of the female's ovulation. From these tests, the doctor may or may not ...
"Studies on fixed-time ovulation induction in the pig". Soc Reprod Fertil Suppl. 66: 187-95. PMID 19848281. A. Labhart (6 ...
The Edinburgh unit was the second in the world to use human gonadotrophins for ovulation induction in humans but Brown, later ... Thornton, S.J., Pepperell, R.J., & Brown, J.B. (1990). Home monitoring of gonadotropin ovulation induction using the Ovarian ... Monitoring Induction of Ovulation by Rapid Radioimmunoassays of Oestrogen and Pregnanediol Glucuronides. Annals of Clinical ... contributions made by Brown in his early days in Edinburgh was the use of human gonadotrophin for the induction of ovulation. ...
Ovulation induction (in the sense of medical treatment aiming for the development of one or two ovulatory follicles) is an ... HCG Injection After Ovulation Induction With Clomiphene Citrate at Medscape. By Peter Kovacs. Posted: 23 April 2004 Humaidan P ... In women with anovulation, it may be an alternative after 7-12 attempted cycles of ovulation induction, since the latter is ... Progesterone elevation on the day of induction of final maturation is associated with lower pregnancy rates in IVF cycles in ...
"Induction of Ovulation in the Human with Human Gonadotropins: Preliminary Report." Obstetrical & Gynecological Survey Buxton, C ... "Timing of Ovulation." American Journal of Obstetrics & Gynecology Buxton, C. Lee. (1956). "Human Infertility." Gynecology & ...
February 1997). "Strategies for ovulation induction and oocyte retrieval in the lowland gorilla". Journal of Assisted ...
... is used for ovulation induction to treat infertility in women with anovulatory disorders. It is given at days three ... Steiner AZ, Terplan M, Paulson RJ (June 2005). "Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta- ... This compound was originally created to work as an estrogen inhibitor, but instead was found to stimulate ovulation in ... September 2007). "Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts". Cell. ...
Fowler and Edwards worked together on controlled ovulation induction in the mouse. In their first joint paper, published in ... Induction of superovulation and pregnancy in mature mice by gonadotrophins. J. Endocrinol. 15, 374-384. Gardner, Sir Richard ( ... FOWLER, R. E., & Edwards, R. G. (1957). Induction of superovulation and pregnancy in mature mice by gonadotrophins. Journal of ...
391-. ISBN 978-3-88763-075-1. Maia H, Barbosa I, Maia H, Nascimento AJ, Bonfim de Souza M (1980). "Induction of ovulation with ... It has been used as a component of ovulation induction in combination with gonadotropin-releasing hormone. List of estrogens G. ...
It can be combined with for example in vitro fertilization and ovulation induction. Progesterone appears to be the best method ... "Progesterone luteal support after ovulation induction and intrauterine insemination: an updated systematic review and meta- ...
"Premature ovarian failure-the prognostic application of autoimmunity on conception after ovulation induction". Fertility and ... sites are free and treatment with exogenous recombinant FSH activates the receptors and normal follicle growth and ovulation ...
For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the ... For patients who do not respond to diet, lifestyle modification and ovulation induction, in vitro fertilisation can be ... Methods that confirm ovulation may be used to evaluate the effectiveness of treatments to stimulate ovulation.[citation needed ... for ovulation induction in infertile women with polycystic ovary syndrome". The Cochrane Database of Systematic Reviews. 9: ...
... predictability of intermittent ovarian function and response to ovulation induction agents". Current Opinion in Obstetrics & ... ready to be released during ovulation. The process of development from a primordial follicle to a pre-ovulatory follicle is ... and progesterone for at least a month in order to suppress their gonadotrophin levels which has been shown to promote ovulation ...
The advantages of the procedure also include its singular treatment, as opposed to several trials of ovulation inductions. ... Laparoscopic ovarian drilling (LOD) may improve the effectiveness of other ovulation induction treatments and results in lower ... "Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome". The Cochrane ... Ovarian drilling is a surgical alternative to CC treatment or recommended for women with WHO Group II ovulation disorders. ...
In some cases, it is used in ovulation induction for reversal of anovulation as well. FSH is available mixed with LH activity ... The mean values for women before ovulation are around (3.8-8.8) mUI/mL. After ovulation these levels drop to between (1.8-5.1) ... This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase ... FSH levels in this time is often called basal FSH levels, to distinguish from the increased levels when approaching ovulation. ...
Mice are polyestrous and breed year round; ovulation is spontaneous. The duration of the estrous cycle is 4-5 days and lasts ... the American Veterinary Medical Association issued new guidelines for CO2 induction, stating that a flow rate of 10% to 30% ...
Sometimes a woman may be uncertain of the date of her last menstrual period, or there may be reason to suspect ovulation ... the risk of failing to recognize multiple gestations and can improve pregnancy dating to reduce the risk of labor induction for ... approximately 3 weeks after ovulation). The embryo should be seen by the time the gestational sac measures 25 mm, about five- ... and assuming ovulation occurred on day fourteen of the menstrual cycle. ...
Uses include: Temporary suppression of fertility in female dogs Induction of ovulation in mares Gonadotropin-releasing hormone ... Final maturation induction after having performed controlled ovarian hyperstimulation. Usage of GnRH agonist for this purpose ... GnRH agonists are useful in: Suppression of spontaneous ovulation as part of controlled ovarian hyperstimulation, which is an ... GnRH agonist for that purpose as well inactivates the axis for which it is intended to work for final maturation induction. ...
Ovulation induction can be achieved either with pulsatile GnRH therapy or alternatively with gonadotropin injections (hCG, FSH ... Dunkel L, Quinton R (June 2014). "Transition in endocrinology: induction of puberty". European Journal of Endocrinology. 170 (6 ... can also be used in male patients to induce secondary sexual characteristic development alongside possible fertility induction ...
In terms of ovulation inhibition, the effective dosage of CPA is 1.0 mg/day while that of medroxyprogesterone acetate is 10 mg/ ... Induction by an estrogen-progesterone synergy". Steroids. 38 (3): 321-331. doi:10.1016/0039-128X(81)90067-2. ISSN 0039-128X. ... Based on ovulation inhibition, a dosage of 50 mg/day cyproterone acetate has on the order of 200 times the progestogenic ... Endrikat J, Gerlinger C, Richard S, Rosenbaum P, Düsterberg B (December 2011). "Ovulation inhibition doses of progestins: a ...
Oliveira, R.G., Tomasi, L., Rovasio, R.A. and Giojalas, L.C. (1999) Increased velocity and induction of chemotactic response in ... to compensate for the lack of coordination between insemination and ovulation. In humans, there are at least two different ...
Induction into the Minnesota Science and Technology Hall of Fame Knight Grand Cross of the Order of the Holy Sepulchre of ... Mary's University Distinguished Alumnus "Transient Distortion in Loudspeakers", May-June 1961 "Ovulation Detection by Internal ... Adducci A, Weidenkopf TE, Garwacki DJ (1965). "Ovulation Detection by Internal Cranial Temperature Measurements". IEEE ... Adducci worked with a local physician and developed an electronic ear thermometer used to detect the time of ovulation in the ...
The main ovulation induction medications include: Antiestrogen, causing an inhibition of the negative feedback of estrogen on ... For women with POI that desire pregnancy, ovulation induction strategies should be avoided and assisted reproduction, such as ... It is said to be the most reliable way of confirming whether ovulation has occurred. Women may also use ovulation predictor ... and increased physical activity can re-establish spontaneously ovulation and improve response to ovulation induction therapy if ...
Skidmore, J. A.; Billah, M.; Allen, W. R. (1 March 1996). "The ovarian follicular wave pattern and induction of ovulation in ... In another study, ovulation could be best induced when the follicle reaches a size of 0.9-1.9 cm (0.35-0.75 in). In another ... Chen, B.X., Yuen, Z.X. and Pan, G.W. (1985). "Semen-induced ovulation in the bactrian camel (Camelus bactrianus)". J. Reprod. ...
Induction of oestrus in anoestrus cows. Treatment of follicular cysts Persistent ovarian follicles Improve oocyte quality ... A dominant follicle develops but there is no ovulation as LH release is prevented by suppression of GnRH. Removal of ... 1983). Multiple use of progesterone releasing intravaginal devices for synchronisation of oestrus and ovulation in cattle. ... progesterone device produces a surge of GnRH, generating a pulse of LH that induces ovulation. Progesterone Releasing ...
... of his other contributions included advancing embryo transfer technology and development of cost-effective ovulation induction ...
The drug was also evaluated for the purpose of ovulation induction and as a treatment of chronic mastitis and endometrial ...
Exposure to nitrogen dioxide causes ovulation-induced oxidative damage to the DNA of ovarian epithelium. There is a growing ... oligomerization of GSTP and induction of the JNK pathway, resulting in apoptosis or inflammation of the bronchioles and ...
Caesareans or inductions are advised after 38 weeks of pregnancy for twins, because the risk of stillbirth increases after this ... O. Bomsel-Helmreich; W. Al Mufti (1995). "The mechanism of monozygosity and double ovulation". In Louis G. Keith; Emile ...
... as a regular contraceptive at 2 mg daily prevents ovulation (1 mg daily does not). A single preovulatory 10-mg ... when followed by a prostaglandin analog Cervical softening and dilation prior to first trimester surgical abortion Induction of ... dose of mifepristone delays ovulation by three to four days and is as effective an emergency contraceptive as a single 1.5-mg ...
Around half of women with epilepsy who menstruate have a lowered seizure threshold around ovulation, most likely from the ... Ottosson UB, Carlström K, Johansson BG, von Schoultz B (1986). "Estrogen induction of liver proteins and high-density ... The contraceptive effects of estrogens are mediated by their antigonadotropic effects and hence by inhibition of ovulation. ... Estrogens mediate their contraceptive effects in combination with progestins by inhibiting ovulation. Estrogens were first ...
Guraya S. S., Dhanju C. K. (November 1992). "Mechanism of ovulation--an overview". Indian J Exp Biol. 30 (11): 958-967. PMID ... Dhindsa J. S.; Sidhu K. S.; Guraya S. S. (September 1995). "Induction of buffalo (Bubalus bubalis ) sperm capacitation and ...
On the other hand, the induction or repression of the expression of genes requires the binding of transcriptional factors to ... During meiotic maturation, the LH peak that precedes ovulation activates MAPK pathway leading to gap junction disruption and ... Ying, QL; Nichols, J; Chambers, I; Smith, A (31 October 2003). "BMP induction of Id proteins suppresses differentiation and ... Kim, J; Bagchi, IC; Bagchi, MK (December 2009). "Control of ovulation in mice by progesterone receptor-regulated gene networks ...
Total number of ovulation in all subjects: 30. % of ovulation in all subjects: 49. Milan Rastislav Henzl; John A. Edwards (10 ... Ottosson UB, Carlström K, Johansson BG, von Schoultz B (1986). "Estrogen induction of liver proteins and high-density ... did not prevent ovulation in all cases. Schacter L, Rozencweig M, Canetta R, Kelley S, Nicaise C, Smaldone L (March 1989). " ... As indexes of the occurrence of ovulation, daily basal temperatures and vaginal smears were taken, and at the nineteenth to ...
Ovulation Induction Archived 2009-10-03 at the Wayback Machine Retrieved on Mars 7, 2010 fertilityLifeLines > Ovulation ... Ovulation induction is usually used in the sense of stimulation of the development of ovarian follicles by fertility medication ... Ovulation Problems and Infertility: Treatment of ovulation problems with Clomid and other fertility drugs. Advanced Fertility ... an injection of the hormone hCG initiates the ovulation process. Egg retrieval should occur from 34 to 36 hours after the hCG ...
... ovulation induction MeSH E02.875.800.984.500 - superovulation MeSH E02.875.800.992 - zygote intrafallopian transfer MeSH ... ovulation inhibition MeSH E02.875.194.910 - sterilization, reproductive MeSH E02.875.540.515 - insemination, artificial, ...
Ovulation Induction Archived 2013-03-10 at the Wayback Machine Retrieved on Mars 7, 2010 > Ovulation Induction Archived ... "Ovulation Induction". Manchester University. Retrieved 2019-04-04. Ovulation Problems and Infertility: Treatment of ovulation ... Ovulation induction is the stimulation of ovulation by medication. It is usually used in the sense of stimulation of the ... The term ovulation induction can potentially also be used for: Final maturation induction, in the sense of triggering oocyte ...
We are considering the use of CPT code 99211 for encounters during cycle management as part of ovulation induction. Nursing ... Monitoring Ovulation Induction By Nurses We are considering the use of CPT code 99211 for encounters during cycle management as ... part of ovulation induction. Nursing staff meets with the patient after ultrasounds are performed and blood work is drawn. ...
Recombinant versus urinary human chorionic gonadotrophin for ovulation induction in assisted reproduction. Review question ...
Ovulation Induction. The principle of ovulation induction is to obtain more than one egg by stimulating the ovaries that ...
Patient predictors for outcome of gonadotrophin ovulation induction in women with normogonadotrophic anovulatory infertility: a ... Ovulation Induction/*methods, Pregnancy, Reference Values, Research Support, Non-U.S. Govt, Treatment Outcome ... gonadotrophin ovulation induction outcome in normogonadotrophic women are obesity and insulin resistance. ... predict clinically significant outcomes of ovulation induction with gonadotrophins, and to obtain pooled estimates of their ...
Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome.. Authors: Weerakiet, S. Srisombut, C. Choktanasiri, ... Weerakiet S, Srisombut C, Choktanasiri W, Rojanasakul A. Efficacy of laparoscopic ovulation induction in polycystic ovary ... After surgery, ovulation was documented in 16 out of 18 (88.9%) patients. Fifteen (71.4%) patients became pregnant. Fourteen ...
Tag: ovulation induction. Anovulation and ovulation induction. Posted on September 11, 2018. August 23, 2022. by admin ...
This is especially helpful for women with irregular periods, which is suggestive of a problem of ovulation, or egg release. ... These medications act to enhance a womans ovulation, and yield a 5-10 % per cycle pregnancy rate when combined with timed ...
What is Ovulation and the things you need to know about your Ovulation Cycle?. Tags : Ovulation inductionOvulation induction ... Ovulation predictor kits (OPK): These kits are easily available over-the-counter (OTC) at any drugstore. The ovulation ... What is Ovulation and the things you need to know about your Ovulation Cycle?. *Home ... it has been found that most of the women are most fertile in the first five days before ovulation and on ovulation day itself. ...
Course Name : Ovulation Induction Protocols in TI/IUI. The aim of this training program is to reinforce the need to have a full ... It also focuses on Case scenarios in ovulation induction.. Eligibility: MBBS, MS, OBG, MD, DGO. Certificate: Yes. At the end of ... understanding of ovulation induction in different patient profiles in basic. ART treatments. It gives an understanding of ...
Odem, R. R. / Concluding remarks : Exploring new frontiers in ovulation induction. In: American journal of obstetrics and ... Concluding remarks : Exploring new frontiers in ovulation induction. / Odem, R. R.. In: American journal of obstetrics and ... Odem, R. R. (1995). Concluding remarks: Exploring new frontiers in ovulation induction. American journal of obstetrics and ... Concluding remarks: Exploring new frontiers in ovulation induction. American journal of obstetrics and gynecology. 1995;172(2 ...
Clomid for ovulation induction may be able to help you welcome a baby. Learn more from our Las Vegas infertility doctors. ... Clomid for ovulation induction can help you welcome a baby. Many patients who visit The Fertility Center of Las Vegas (FCLV) ... Then, the increased LH stimulates ovulation, which releases the egg or eggs. ... the next step is for you to take a trigger shot or use an ovulation kit. From there, treatment will either be timed intercourse ...
However, thanks to Ovulation Induction treatment, they are now besotted parents to daughter Tiggy and baby son Radley. ... "We were told that if we didnt conceive a child after 4 rounds of Ovulation Induction, we would have to look into other options ... At this point, the couple were recommended Ovulation Induction treatment with a drug called Gonal F. Gonal F is a hormonal ... Increasingly conscious of the four attempts of Ovulation Induction advised by Dr Ingamells, the couple embarked on their fourth ...
Letrozole for induction of ovulation, jim harbaugh natural steroids. Letrozole for induction of ovulation, Jim harbaugh natural ... Terms of ovulation induction and pregnancy rate. Clomiphene citrate, endometrial thickness, letrozole, ovulation induction. ... International Journal of Sport Nutrition, letrozole for induction of ovulation. Letrozole for induction of ovulation, buy ... letrozole for induction of ovulation.. Letrozole for induction of ovulation, jim harbaugh natural steroids Lets look at how to ...
7th World World Congress on Ovulation Induction. 7th World World Congress on Ovulation Induction. 03/09/2015 - 05/09/2015 ...
Discussing about Patients With Low Ovarian Reserve and its causes, risk factors and treatments in both men and women.
Managing the anovulatory state: medical induction of ovulation. Number 197. Committee on Technical Bulletins of the American ... A cycle begins when a woman starts taking ovulation-inducing drugs or starts ovarian monitoring with the intent of having ... First, reliable information could not be obtained on the availability and use of ovulation-inducing drugs in the United States ... In the United States, pregnancies associated with assisted reproductive technology (ART) or ovulation-inducing drugs are more ...
First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. Hum Reprod Update. ... 362-ovulation induction in polycystic ovary syndrome. J Obstet Gynaecol Can. 2018 Jul;40(7):978-87. Abstract ... First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. Hum Reprod Update. ... Gonadotrophins for ovulation induction in women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2019 Jan 16;1: ...
Ovulation induction in polycystic ovary syndrome. J Obstet Gynaecol Can. 2010 May. 32(5):495-502. [QxMD MEDLINE Link]. ... First-line treatment for ovulation induction when fertility is desired are letrozole or clomiphene citrate. [3, 4, 6] ... Altering hirsutism through ovulation induction in women with polycystic ovary syndrome. Obstet Gynecol. 2012 Jun. 119(6):1151-6 ... Badawy A, State O, Abdelgawad S. N-Acetyl cysteine and clomiphene citrate for induction of ovulation in polycystic ovary ...
Ovulation Tracking Ovulation Induction ICSI - Intra cytoplasmic Sperm Injection Mini-IVF/ICSI ...
Does ovulation induction increase the risk of gynecological cancer?. Does ovulation induction increase the risk of ... On the contrary, many studies suggest that drugs used for ovulation induction may increase the risk of uterine cancers. More ... Ovulation induction, cancer, ovarian cancer, breast cancer, endometrial cancer, gynecologic cancer, clomiphene citrate, ... The risk of developing gynaecological cancer following ovulation induction therapy in infertile patients is not easy to ...
Clomiphene citrate for ovulation induction in women with oligo-amenorrhoea: Cochrane systematic review answers are found in the ... "Clomiphene Citrate for Ovulation Induction in Women With Oligo-amenorrhoea: Cochrane Systematic Review." Cochrane Abstracts, ... Clomiphene citrate for ovulation induction in women with oligo-amenorrhoea: Cochrane systematic review. In Cochrane Abstracts ... Clomiphene citrate for ovulation induction in women with oligo-amenorrhoea: Cochrane systematic review is a topic covered in ...
Ovulation induction using fertility medications is the first step of most fertility treatments at our practice. By increasing ... What Exactly Is Ovulation Induction? Superovulation, or ovulation induction is the first stage in many fertility treatments ... Irregular Ovulation Conditions like anovulation (absence of ovulation) and oligo-ovulation (irregular ovulation) prevent your ... Understanding Clomid and Ovulation Induction Clomiphene Citrate (clomid) induces ovulation in women who dont regularly ovulate ...
Ovulation Induction. Induction of ovulation and pregnancy in anovulatory infertile women when cause of infertility is ... Ovarian neoplasms (infrequent reports in women who have undergone multiple drug regimens for ovulation induction; causal ... Indicated for induction of spermatogenesis in men with primary and secondary hypogonadotropic hypogonadism (HH) in whom the ...
... women underwent standardized ovulation induction with clomiphene citrate and timed intercourse for four cycles. Pregnancies ... Main outcome measures: Weight, ovulation, and live birth were measured. Results: We consented 216 and randomly assigned 149 ... Cumulative ovulation rates were superior after weight loss: OCP, 46%; Lifestyle, 60%; and Combined, 67% (P , .05). Live birth ...
Ovulation induction (OI). 12%. Intrauterine insemination (IUI). 11%. Intracytoplasmic sperm injection (ICSI). 9%. ...
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Pregnyl (chorionic gonadotropin (hcg)) for Ovulation Induction Took this one time dose to induce ovulation. Said to work ... Pregnyl (chorionic gonadotropin (hcg)) for Ovulation Induction Alongside almost daily ultrasounds, it was the only medicine ...
Ovulation Induction. The goal of this treatment is exactly what the name implies: to induce ovulation when its absent or ... Clomiphene citrate (Clomid, Serophene) is a commonly used ovulation induction medication. It works at the level of the brain ... For women who do ovulate, ovulation induction can stimulate more eggs.. Intrauterine Insemination (IUI). Intrauterine ... or due to irregular or absent ovulation. ...
  • Ovulation induction helps reversing anovulation or oligoovulation, that is, helping women who do not ovulate on their own regularly, such as those with polycystic ovary syndrome (PCOS). (
  • Although there are certain things like stress or improper diet which can also impact the exact day of ovulation from month to month or there can be medical conditions as well like polycystic ovary syndrome (PCOS) or amenorrhea that may make woman's ovulation irregular or stop completely. (
  • Citrate (cc) (100 mg) for ovulation induction in women with polycystic ovary syndrome. (
  • IMSEAR at SEARO: Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome. (
  • Weerakiet S, Srisombut C, Choktanasiri W, Rojanasakul A. Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome. (
  • First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. (
  • If you've ever come face to face with hormonal conditions that could have hampered your fertility, such as polycystic ovary syndrome, hypopituitarism or endometriosis, chances are, that your hormonal reserves need to be optimised through ovulation induction. (
  • Dr. Perloe has served as principal investigator in numerous reproductive health research studies including innovative IVF treatments, ovulation induction, and polycystic ovary syndrome. (
  • These medications act to enhance a woman's' ovulation, and yield a 5-10 % per cycle pregnancy rate when combined with timed intercourse or intrauterine insemination (IUI). (
  • When combined with fertility treatments like IVF and intrauterine insemination , ovulation induction can greatly improve your chances of successfully becoming pregnant and experiencing a live birth. (
  • Superovulation, or ovulation induction is the first stage in many fertility treatments including in vitro fertilization , intrauterine insemination , and egg donation . (
  • Intrauterine insemination (IUI) is a fertility treatment where a doctor inserts sperm directly into the uterus during ovulation. (
  • Infertility in women is often treated with oral ovulation induction medications such as Clomid and Femara, with or without intrauterine insemination. (
  • DGFC provides specialised treatment with services such as intra-cytoplasmic sperm injection (ICSI), in vitro fertilization (IVF), testicular sperm aspiration (Tesa), percutaneous epididymal sperm aspiration (PESA), freezing of eggs and sperm, intrauterine insemination (IUI) , ovulation induction, gender selection, detection of genetic anomalies etc. (
  • A systematic review was conducted to determine whether initial screening characteristics of women with normogonadotrophic anovulatory infertility predict clinically significant outcomes of ovulation induction with gonadotrophins, and to obtain pooled estimates of their predictive value through meta-analysis. (
  • Letrozole should be considered first line pharmacological treatment for ovulation induction in women with pcos with anovulatory infertility and no other. (
  • These include the fact that infertility in itself is a known risk factor for some of these cancers, that these patients are subjected to increased surveillance compared to the general population and that the drugs used for ovulation induction are sometimes used in combination. (
  • Here are three ways undergoing ovulation stimulation at The Center for Fertility and Gynecology in Los Angeles, CA, can help you overcome infertility. (
  • This low intervention option is helpful when the cause of your infertility is unexplained, caused by a cervical factor, or due to irregular or absent ovulation. (
  • Rancic's fertility story and the stories of other high-profile women such as Liz Tilberis (the late editor-in-chief of Harper's Bazaar), Gilda Radner (Saturday Night Live comedienne), and author and activist Elizabeth Edwards -- all of whom died of either ovarian or breast cancer after multiple cycles of ovulation and induction - demonstrate the need for a more meaningful public debate about the nature and root causes of infertility. (
  • Induction of ovulation and pregnancy in patients with functional anovulatory infertility without primary ovarian failure. (
  • Published May 16, 2013 at 400 × 298 in Evaluation of Infertility, Ovulation Induction and Assisted Reproduction . (
  • There are many causes of infertility, including problems with ovulation (the release of an egg from a woman's ovary), fertilisation by a man's sperm and implantation of the fertilised egg into the lining of the woman's uterus. (
  • If your health care provider recommends this treatment, and if the first two or three attempts are unsuccessful, ask about a referral to a provider who specializes in infertility, such as myself, so the treatment may be closely monitored and fine-tuned to maximize changes of ovulation before more expensive and complex treatment options must be considered. (
  • Pregnancies with multiple gestations are associated with serious infant and maternal health risks as well as psychological distress and significant financial consequences, and are a far too common consequence of infertility treatments such as assisted reproductive technology (ART) and ovulation induction drugs. (
  • Letrozole for induction of ovulation in pcos patients: resistant to clomiphene citrate south asian federation of obstetrics and gynaecology. (
  • Mechanism of letrozole action in ovulation induction (clomiphene citrate treatment). (
  • Cochrane Abstracts , Evidence Central , (
  • After preconception intervention, women underwent standardized ovulation induction with clomiphene citrate and timed intercourse for four cycles. (
  • Clomiphene citrate (Clomid, Serophene) is a commonly used ovulation induction medication. (
  • First-line treatment for ovulation induction when fertility is desired are letrozole or clomiphene citrate. (
  • Clomiphene citrate is typically not effective for inducing ovulation in these patients. (
  • And we also use ovulation-induction agents like clomiphene citrate to bring on ovulation. (
  • E2 (suppositories) and progesterone to CC (clomiphene citrate) ovulation induction regimens normalizes the alterations in endometrial morphology. (
  • In summary, clomiphene citrate is a viable alternative for ovulation induction. (
  • Also, where anovulation or oligovulation is secondary to another disease, the treatment for the underlying disease can be regarded as ovulation induction, by indirectly resulting in ovulation. (
  • Flinders fertility offers cycle monitoring and ovulation induction (oi) with clomid, letrozole, or fsh injections for patients with anovulation. (
  • Conditions like anovulation (absence of ovulation) and oligo-ovulation (irregular ovulation) prevent your ovaries from naturally releasing mature eggs in a regular, predictable cycle. (
  • Sporadic menstruation is usually induced by a hormonal disequilibrium, leading to anovulation or infrequent ovulation. (
  • 1 Women with PCOS who are trying to conceive are sometimes prescribed clomiphene (Clomid,™ Serophene ® ), a fertility drug that stimulates ovulation. (
  • Research done on animals has shown some promise for fenugreek's potential role as a natural alternative to ovulation stimulant drugs such as Clomid. (
  • Ovulation induction is the stimulation of ovulation by medication. (
  • Through advanced diagnostic tests, our doctors can determine whether ovulation stimulation is appropriate. (
  • Conclusive evidence on the correlation between fenugreek and ovulation stimulation is very difficult to find. (
  • By definition, women with pcos do not spontaneously ovulate each month such that fertility treatments, specifically, ovulation induction, is. (
  • Ovulation induction is the first step in most fertility treatments . (
  • We are also starting ovulation induction and in vitro fertilization cycles. (
  • Some of the most common assisted human reproductive technologies include ovulation induction, artificial insemination, in-vitro fertilization, donor conception, and surrogacy. (
  • In vitro-fertilisering (IVF), eller provrörsbefruktning, är en fertilitetsmetod där en kvinnas ägg tas ut från en äggstock för att befruktas av en mans spermie utanför en kvinnas kropp ( in vitro ), i stället för i en kvinnas äggledare som efter ett samlag eller vid insemination, och därefter återföras till en livmoder In vitro fertilisation is the most common type of reproductive medicine treatment . (
  • the biggest reason for the increased rate of premature newborns is the increase in women who are impregnated through in vitro fertilization and ovulation induction, practices that can double or triple the possibility of having twins or triplets. (
  • In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (
  • Adult women with hypogonadotropic hypogonadism who desire fertility undergo ovulation induction with injectable gonadotropins. (
  • If ovulation is induced incorrectly, it could lead to a condition called ovarian hyperstimulation syndrome. (
  • Conclusion: tamoxifen should be the first choice to induce ovulation in anovulatory pco women. (
  • Ovulation induction prepares at least one egg in every cycle to meet its potential suitor, the sperm. (
  • A medication called metformin treats diabetes and can also help improve menstrual cycles and ovulation in women with PCOS. (
  • Patients prescribed Letrozole or Clomiphene for ovulation induction have been advised to stop the medication immediately. (
  • IUI can be done with a natural ovulation cycle or ovulation induction with medication. (
  • They also take a medication to prevent premature ovulation. (
  • During IUI and IVF cycles, while the woman is on medication for ovulation induction, it is important that the follicular growth be monitored by ultrasonography. (
  • A simple treatment that uses medication to stimulate the ovaries and encourage ovulation. (
  • The term ovulation induction can potentially also be used for: Final maturation induction, in the sense of triggering oocyte release from relatively mature ovarian follicles during late follicular phase. (
  • Controlled ovarian hyperstimulation (stimulating the development of multiple follicles of the ovaries in one single cycle), has also appeared in the scope of ovulation induction. (
  • By increasing certain hormones in the body, the treatment triggers ovulation and increases the number of follicles that are available for harvesting. (
  • On Cloudnine, we monitor ovulation induction cycles continually through pelvic ultrasounds, to measure how well the follicles are developing and how thick the endometrium is growing. (
  • Patients with menstrual cycles longer than 30 days, irregular ovulation and menstruation, the production of more than 20 follicles, are all at higher risk. (
  • The principle of ovulation induction is to obtain more than one egg by stimulating the ovaries that usually produce only one egg cell. (
  • Only those studies in which pre-treatment screening characteristics (such as body mass index, serum LH and androgens, insulin sensitivity and ultrasound appearance of ovaries) were related to outcome parameters (such as total amount of FSH administered, cancellation, ovulation, pregnancy and miscarriage), were included in this analysis. (
  • Ovulation is a process which happens usually once in every menstrual cycle in which hormone changes and ovaries are triggered to release an egg. (
  • At the time of your ovulation each month one of your ovaries will release a mature egg, which will travel into one of the woman's fallopian tubes. (
  • Polycystic ovarian syndrome (PCOS) - a hormonal endocrine disorder that affects more than 5 million women in the United States alone - manifests itself through a spectrum of symptoms, including irregular or absent menstruation (known as amenorrhea), lack of ovulation, multiple cysts on the ovaries, acne, excessive facial hair (hirsutism), and obesity. (
  • The LH surge causes the release of the mature egg from the woman ovary and this entire procedure is known as ovulation. (
  • The impact of ovulation-inducing drugs not associated with an ART procedure was estimated by subtracting both ART-related births (from the SART reporting system) and spontaneously occurring triplet and higher-order multiple births ( 6 ) from the total number of these births. (
  • Ovulation induction is an ideal procedure for women whose menstrual cycles do not follow a predictable pattern. (
  • Ovulation induction is a completely safe, non-invasive procedure, suited for most women with a yoyoing hormone graph. (
  • We know that a traditional ovulation induction procedure poses risks to a woman, of which some are mentioned below. (
  • A higher dose of up to 12.5 mg per day results in increased follicular growth and a higher number of predicted ovulations, without a detrimental effect on endometrial thickness, and is considered in those who do not respond adequately to a lower dose. (
  • This involves stimulating the woman's ovulation process through the use of oral medications and the regular injection of follicle-stimulating hormones like gonadotropin. (
  • The main alternatives for ovulation induction medications are: Antiestrogen, causing an inhibition of the negative feedback of estrogen on the pituitary gland, resulting in an increase in secretion of follicle-stimulating hormone. (
  • We incorporate medications and hormone therapy to induce ovulation. (
  • At the Center for Fertility and Gynecology in Los Angeles , we accomplish ovulation induction through the use of different medications and hormones. (
  • Ovulation induction using medications to improve ovulation. (
  • Ovulation induction medications. (
  • The egg donor self-administers ovulation induction medications to cause multiple eggs to mature. (
  • Severe ovarian hyperstimulation is a rare complication of ovulation induction therapy. (
  • 5 mg) and anastrozole (1 mg) meant for ovulation induction in clomiphene (cc)-resistant women with pcos. (
  • Surgical management of PCOS is aimed mainly at restoring ovulation. (
  • Women with PCOS who lose weight are more likely to have restored ovulation and improved pregnancy rates. (
  • Ovarian drilling is a surgical treatment that can stimulate ovulation in women with PCOS. (
  • Studies of women with PCOS have shown that ovarian drilling results in an 80% ovulation rate and a 50% pregnancy rate. (
  • Taking inositol by mouth seems to lower triglyceride levels , decrease blood pressure, and improve blood sugar , ovulation , and pregnancy rates in people with PCOS. (
  • Aside from helping women who have PCOS to lose weight, the keto diet can also help to rebalance the hormones, which is needed for ovulation. (
  • At this point, the couple were recommended Ovulation Induction treatment with a drug called Gonal F. Gonal F is a hormonal treatment given through a series of self-administered injections to stimulate ovulation. (
  • In conclusion, the best available evidence, though limited, suggests that the most clinically useful predictors of gonadotrophin ovulation induction outcome in normogonadotrophic women are obesity and insulin resistance. (
  • This is especially helpful for women with irregular periods, which is suggestive of a problem of ovulation, or egg release. (
  • The time when women approach ovulation her body starts producing an increased amount of hormone called estrogen. (
  • The egg of the woman can only be fertilized for up to 24 hours after ovulation, however, if it is not fertilized after 24 hours of ovulation then the lining of the womb is shed which means the mature egg is lost and women period begins. (
  • According to the study, it has been found that most of the women are most fertile in the first five days before ovulation and on ovulation day itself. (
  • There are many cases where the cycle lengths vary and ovulation occurs 14 days prior to the women next period begins. (
  • c) How women can track their ovulation time? (
  • The fertility experts at Fertility Center Nepal suggest the best way for the women to confirm when she ovulates is with an ultrasound in the hospital or clinic, or also they can track their ovulation time with hormonal blood tests at home. (
  • Ovulation is confirmed after the women temperature has stayed elevated from her baseline for three days. (
  • The ovulation predictor kit will detect the presence of LH in the women urine and you will be able to ovulate within the next couple of days after the result line is as dark as the control. (
  • If the women track her ovulation from one month to the next month and she will be able to notice that either she is not ovulating regularly or in some cases, they are not ovulating at all. (
  • For women who do ovulate, ovulation induction can stimulate more eggs. (
  • Ovulation induction is a treatment commonly elected by women who experience irregular or absent ovulatory cycles. (
  • All the women had an endometrial biopsy ten days after ovulation. (
  • Avoid intercourse for women with significant ovarian enlargement after ovulation. (
  • Women who undergo ovulation induction and with a Leading follicular size of 18mm or more in transvaginal ultrasound scan (TVS) c. (
  • The best thing about it is that two of the four women conceived spontaneously without the need for ovulation induction. (
  • In a study with more than 6,100 pregnant women across the country, researchers randomly assigned half of the women to an expectant management group (waiting for labor to begin on its own and intervening only if problems occur) and the other half to a group that would undergo an elective induction (inducing labor without a medical reason) at 39 weeks of gestation. (
  • If you haven't been able to gauge the beat of your ovulatory cycles, it's possible that your ovulation is infrequent or absent. (
  • Also, risk seems zero to minimal with less than 12 cycles of ovulation induction during IVF. (
  • As part of your ovulation induction treatment cycle your doctor has prescribed either clomiphene or letrozole tablets or fsh injections to stimulate the. (
  • Ovulation induction aims to open up frequent fertile windows, during which a schedule for intercourse is recommended. (
  • I have gone through 3 TSI's (stimulated/timed ovulation and intercourse) and started IVF two months ago but they cancelled it on me as my egg growth was too quick on one egg and the rest were too slow. (
  • Ovulation (release of on ovum by an ovary) during an ongoing pregnancy. (
  • Corpus Luteum - A special gland that forms on the surface of the ovary at the site of ovulation and produces progesterone during the second half of the cycle. (
  • Ovulation induction lets you slip into a subtle programmed monthly cycle, allowing your body to replenish its hormone levels and resume ovulation. (
  • Fenugreek also contains phytoestrogens, compounds that act like the hormone estrogen, one of the hormones regulating ovulation. (
  • Once the eggs are sufficiently grown as per the scan and hormone tests, you will receive injection Hcg as an ovulation trigger. (
  • The goal of this treatment is exactly what the name implies: to induce ovulation when it's absent or irregular. (
  • Also, Gonal-F: Induction of spermatogenesis in men with hypogonadotropic hypogonadism without primary testicular failure. (
  • The hormonal support consisted of estradiol suppositories (E2) 0.1 mg twice a day from day eight until the LH surge followed by progesterone gel applied close to the uterus as directed beginning three days after ovulation. (
  • Ovulation was induced in three of four hCG-treated mares that also developed prolonged luteal phases, as assessed by progesterone analysis. (
  • The rats given fenugreek extract seemed to show significant elevation of estrogen and progesterone, two hormones crucial in inducing ovulation. (
  • Progesterone helps the production of estrogen, and both hormones are necessary in adequate supply for ovulation to occur. (
  • However, thanks to Ovulation Induction treatment, they are now besotted parents to daughter Tiggy and baby son Radley. (
  • Increasingly conscious of the four attempts of Ovulation Induction advised by Dr Ingamells, the couple embarked on their fourth round of treatment. (
  • Objetive: to compare the efficacy of letrozole vs. Treatment with letrozole for ovulation induction is off-licence as the drug company has not applied for a specific license to allow. (
  • If you have been considering IVF , egg freezing , or another type of fertility treatment and would like to learn more about ovulation induction, reach out to our Los Angeles, CA, office. (
  • Ovulation induction is composed of a string of steps, which are seamlessly sewn together to create a treatment plan. (
  • In addition, since treatment with progestins to suppress oestrous cyclicity in competition mares is not endorsed by most European Community countries, a preliminary study was performed to determine if dioestrous ovulations and a subsequent prolonged luteal phase can be induced using human chorionic gonadotropin (hCG). (
  • On the contrary, many studies suggest that drugs used for ovulation induction may increase the risk of uterine cancers. (
  • In the United States, pregnancies associated with assisted reproductive technology (ART) or ovulation-inducing drugs are more likely to result in multiple births than spontaneously conceived pregnancies ( 1 ). (
  • This report provides estimates of the contribution of ART and ovulation-inducing drugs to these birth outcomes for 1996 and 1997, and summarizes trends during 1980--1997, which indicate that the ratio of triplet and higher-order multiple births has more than quadrupled and that a large proportion of this increase can be attributed to ART or the use of ovulation-inducing drugs. (
  • this trend began after the Food and Drug Administration approved two ovulation-inducing drugs, one in 1967 and another in 1970. (
  • For both years, approximately 20% were attributable to spontaneously occurring triplets and higher-order multiple births and approximately 40% were attributable to ovulation-inducing drugs without ART. (
  • Perinatal risk factors that have a suggested association include β 2 adrenergic receptor agonists, labor induction and augmentation, maternal infection and disease (i.e., antiphospholipid syndrome), antiepileptic drugs, cocaine use, and oral supplements. (
  • Ovulation can be induced either through oral drugs or through injectables. (
  • Odem, RR 1995, ' Concluding remarks: Exploring new frontiers in ovulation induction ', American journal of obstetrics and gynecology , vol. 172, no. 2 II, pp. 792. (
  • Dr. Kaberi Banerjee, Medical Director, Advanced Fertility & Gynecology Center, New Delhi will discuss how to induce ovulation in this video. (
  • A preconception weight loss intervention eliminates the adverse metabolic oral contraceptive effects and, compared with oral contraceptive pretreatment, leads to higher ovulation rates. (
  • Given that the administration of hCG appears to be the precipitating event for developing OHSS, an alternative to hCG induced ovulation triggering (such as GnRH agonist or Lupron) can avoid the risk of OHSS. (
  • We are considering the use of CPT code 99211 for encounters during cycle management as part of ovulation induction. (
  • What is Ovulation and the things you need to know about your Ovulation Cycle? (
  • I have a regular menstrual cycle and ovulation. (
  • I rarely have to cancel an ovulation induction cycle using FSH. (
  • In the simplest terms, letrozole induces ovulation. (
  • The Lupron trigger induces the release of LH and FSH from the pituitary which then effectively induces oocyte maturation for either retrieval or ovulation induction. (
  • Polycystic ovarian syndrome patients with normospermic partners undergoing ovulation induction with letrozole had a higher live birth rate. (
  • After surgery, ovulation was documented in 16 out of 18 (88.9%) patients. (
  • The risk of developing gynaecological cancer following ovulation induction therapy in infertile patients is not easy to determine due to many confounding factors. (
  • These findings provide new insight into the uterine epithelial changes and angiogenesis at the 3D level, and explain a potential reason for endometrial changes due to the low implantation rate in patients undergoing clinic super-ovulation. (
  • Patients who did not respond to ovulation induction d. (