Ovulation induction. Medical search

Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.

Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.

Compounds which increase the capacity to conceive in females.

Diminished or absent ability of a female to achieve conception.

Extracts of urine from menopausal women that contain high concentrations of pituitary gonadotropins, FOLLICLE STIMULATING HORMONE and LUTEINIZING HORMONE. Menotropins are used to treat infertility. The FSH:LH ratio and degree of purity vary in different preparations.

A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.

A complication of OVULATION INDUCTION in infertility treatment. It is graded by the severity of symptoms which include OVARY enlargement, multiple OVARIAN FOLLICLES; OVARIAN CYSTS; ASCITES; and generalized EDEMA. The full-blown syndrome may lead to RENAL FAILURE, respiratory distress, and even DEATH. Increased capillary permeability is caused by the vasoactive substances, such as VASCULAR ENDOTHELIAL GROWTH FACTORS, secreted by the overly-stimulated OVARIES.

A major gonadotropin secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and the LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. The alpha subunit is common in the three human pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.

The ratio of the number of conceptions (CONCEPTION) including LIVE BIRTH; STILLBIRTH; and fetal losses, to the mean number of females of reproductive age in a population during a set time period.

A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.

The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.

Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.

The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).

An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.

The event that a FETUS is born alive with heartbeats or RESPIRATION regardless of GESTATIONAL AGE. Such liveborn is called a newborn infant (INFANT, NEWBORN).

An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.

Human artificial insemination in which the husband's semen is used.

Methods pertaining to the generation of new individuals, including techniques used in selective BREEDING, cloning (CLONING, ORGANISM), and assisted reproduction (REPRODUCTIVE TECHNIQUES, ASSISTED).

Procedures using an electrically heated wire or scalpel to treat hemorrhage (e.g., bleeding ulcers) and to ablate tumors, mucosal lesions, and refractory arrhythmias. It is different from ELECTROSURGERY which is used more for cutting tissue than destroying and in which the patient is part of the electric circuit.

The condition of carrying two or more FETUSES simultaneously.

A potent synthetic agonist of GONADOTROPIN-RELEASING HORMONE with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central PRECOCIOUS PUBERTY and ENDOMETRIOSIS.

Occurrence or induction of release of more ova than are normally released at the same time in a given species. The term applies to both animals and humans.

Clinical and laboratory techniques used to enhance fertility in humans and animals.

Inability to reproduce after a specified period of unprotected intercourse. Reproductive sterility is permanent infertility.

A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)

The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.

A protein extract of human menopausal urine in which LUTEINIZING HORMONE has been partially or completely removed. Urofollitropin represents FOLLICLE STIMULATING HORMONE from the urine.

A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.

Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; SPONTANEOUS ABORTION; INDUCED ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO.

The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.

The discharge of an OVUM from a rupturing follicle in the OVARY.

The induction of local hyperthermia by either short radio waves or high-frequency sound waves.

A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications.

Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies.

An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis.

The transfer of mammalian embryos from an in vivo or in vitro environment to a suitable host to improve pregnancy or gestational outcome in human or animal. In human fertility treatment programs, preimplantation embryos ranging from the 4-cell stage to the blastocyst stage are transferred to the uterine cavity between 3-5 days after FERTILIZATION IN VITRO.

The period from onset of one menstrual bleeding (MENSTRUATION) to the next in an ovulating woman or female primate. The menstrual cycle is regulated by endocrine interactions of the HYPOTHALAMUS; the PITUITARY GLAND; the ovaries; and the genital tract. The menstrual cycle is divided by OVULATION into two phases. Based on the endocrine status of the OVARY, there is a FOLLICULAR PHASE and a LUTEAL PHASE. Based on the response in the ENDOMETRIUM, the menstrual cycle is divided into a proliferative and a secretory phase.

The period in the MENSTRUAL CYCLE that follows OVULATION, characterized by the development of CORPUS LUTEUM, increase in PROGESTERONE production by the OVARY and secretion by the glandular epithelium of the ENDOMETRIUM. The luteal phase begins with ovulation and ends with the onset of MENSTRUATION.

The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.

The capacity to conceive or to induce conception. It may refer to either the male or female.

Procedures to obtain viable OOCYTES from the host. Oocytes most often are collected by needle aspiration from OVARIAN FOLLICLES before OVULATION.

The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle (OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes.

The number of births in a given population per year or other unit of time.

Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).

A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.

Blocking the process leading to OVULATION. Various factors are known to inhibit ovulation, such as neuroendocrine, psychological, and pharmacological agents.

The mucous membrane lining of the uterine cavity that is hormonally responsive during the MENSTRUAL CYCLE and PREGNANCY. The endometrium undergoes cyclic changes that characterize MENSTRUATION. After successful FERTILIZATION, it serves to sustain the developing embryo.

An assisted fertilization technique consisting of the microinjection of a single viable sperm into an extracted ovum. It is used principally to overcome low sperm count, low sperm motility, inability of sperm to penetrate the egg, or other conditions related to male infertility (INFERTILITY, MALE).

The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.

The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.

Proteins prepared by recombinant DNA technology.

The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.

The number of offspring produced at one birth by a viviparous animal.

Endometrial implantation of EMBRYO, MAMMALIAN at the BLASTOCYST stage.

Elements of limited time intervals, contributing to particular results or situations.

Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.

Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

Occurrence or induction of ESTRUS in all of the females in a group at the same time, applies only to non-primate mammals with ESTROUS CYCLE.

The period of the MENSTRUAL CYCLE representing follicular growth, increase in ovarian estrogen (ESTROGENS) production, and epithelial proliferation of the ENDOMETRIUM. Follicular phase begins with the onset of MENSTRUATION and ends with OVULATION.

A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy.

Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.

Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.

Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.

Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.

Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.

Methods for recognizing the state of ESTRUS.

Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).

Achievement of full sexual capacity in animals and in humans.

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

A state of sexual inactivity in female animals exhibiting no ESTROUS CYCLE. Causes of anestrus include pregnancy, presence of offspring, season, stress, and pathology.

The production of offspring by selective mating or HYBRIDIZATION, GENETIC in animals or plants.

The period of cyclic physiological and behavior changes in non-primate female mammals that exhibit ESTRUS. The estrous cycle generally consists of 4 or 5 distinct periods corresponding to the endocrine status (PROESTRUS; ESTRUS; METESTRUS; DIESTRUS; and ANESTRUS).

An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.

Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.

A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.

A phase of the ESTROUS CYCLE that precedes ESTRUS. During proestrus, the Graafian follicles undergo maturation.

Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.

Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.

Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.

The total process by which organisms produce offspring. (Stedman, 25th ed)

In females, the period that is shortly after giving birth (PARTURITION).

The potential of the FETUS to survive outside the UTERUS after birth, natural or induced. Fetal viability depends largely on the FETAL ORGAN MATURITY, and environmental conditions.

A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.

Peptides, natural or synthetic, that stimulate the release of PITUITARY HORMONES. They were first isolated from the extracts of the HYPOTHALAMUS; MEDIAN EMINENCE; PITUITARY STALK; and NEUROHYPOPHYSIS. In addition, some hypophysiotropic hormones control pituitary cell differentiation, cell proliferation, and hormone synthesis. Some can act on more than one pituitary hormone.

The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.

Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively

A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle.

The complex processes of initiating CELL DIFFERENTIATION in the embryo. The precise regulation by cell interactions leads to diversity of cell types and specific pattern of organization (EMBRYOGENESIS).

The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.

One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.

Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).

Unsaturated androstanes which are substituted with one or more hydroxyl groups in any position in the ring system.

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR) that stimulate gonadal functions in both males and females. They include FOLLICLE STIMULATING HORMONE that stimulates germ cell maturation (OOGENESIS; SPERMATOGENESIS), and LUTEINIZING HORMONE that stimulates the production of sex steroids (ESTROGENS; PROGESTERONE; ANDROGENS).

Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.

The degeneration and resorption of an OVARIAN FOLLICLE before it reaches maturity and ruptures.

Established cell cultures that have the potential to propagate indefinitely.

Passive or active movement of SPERMATOZOA from the testicular SEMINIFEROUS TUBULES through the male reproductive tract as well as within the female reproductive tract.

The process of bearing developing young (EMBRYOS or FETUSES) in utero in non-human mammals, beginning from FERTILIZATION to BIRTH.

Differential transcriptional activity associated with chromatin configuration in fully grown mouse germinal vesicle oocytes. (1/1572)

It was previously shown that fully grown ovarian germinal vesicle (GV) oocytes of adult mice exhibit several nuclear configurations that differ essentially by the presence or absence of a ring of condensed chromatin around the nucleolus. These configurations have been termed, respectively, SN (surrounded nucleolus) and NSN (nonsurrounded nucleolus). Work from our and other laboratories has revealed ultrastructural and functional differences between these two configurations. The aims of the present study were 1) to analyze the equilibrium between the SN and the NSN population as a function of the age of the mice and the time after hCG-induced ovulation and 2) to study the polymerase I (pol I)- and polymerase II (pol II)-dependent transcription in both types of oocytes through the detection of bromouridine incorporated into nascent RNA. We show 1) that ovarian GV oocytes exhibiting the SN-type configuration can be found as soon as 17 days after birth in the C57/CBA mouse strain and 2) that the SN:NSN ratio of ovarian GV oocytes is very low just after hCG-induced ovulation and then increases progressively with the time after ovulation. Furthermore, we demonstrate that the SN configuration correlates strictly with the arrest of both pol I- and pol II-dependent transcription in mice at any age. Finally, we show that ribosomal genes are located at the outer periphery of the nucleolus in the NSN configuration and that pol I-dependent perinucleolar transcription sites correspond to specific ultrastructural features of the nucleolus. Altogether, these results provide clear-cut criteria delineating transcriptionally active GV oocytes from those that are inactive, and confirm that the SN-type configuration is mostly present in preovulatory oocytes. (+info)

Ovarian follicular responses in dairy cows treated with GnRH and cloprostenol. (2/1572)

Lactating, nonpregnant (with a corpus luteum) Holsteins were given 100 ug GnRH (n = 12) or saline (n = 12) and 500 ug cloprostenol 6 d later. Following luteolysis, ovulation occurred 10.1 +/- 0.2 d (range, 9-12 d) after GnRH and 8.6 +/- 1.0 d (range, 3-12 d) after saline (differences between groups: means, P > 0.05; variability, P < 0.001). Treatment with GnRH and cloprostenol resulted in a relatively synchronous ovulation. (+info)

Effect of exogenous gonadotropins on gonadotrophs of the rat pituitary gland. (3/1572)

In the human in vitro fertilization (IVF) program a variety of superovulation regimens have been employed to promote follicular stimulation and the recruitment of supernumerary oocytes. This therapy, however, disturbs serum concentrations of estradiol and progesterone and may disrupt the normal feedback systems of the hypothalamo-pituitary axis. This study examines the effects of hyperstimulation on the pituitary gonadotrophs and circulating gonadotrophins. FSH and human chorionic gonadotropin (hCG) were administered to normal cycling female Sprague-Dawley rats (n = 12) in phase with their estrous cycle. Control rats (n = 12) were injected with saline. In both the experimental and control groups, six rats were mated on the evening of proestrus and killed 12 hr later, while six animals were killed prior to mating. Blood was collected at the time of sacrifice for radioimmunoassay. The pituitary glands were removed, processed for light microscopy and serially sectioned. Immunocytochemistry for LH and FSH was carried out to determine the area occupied by these cell types. Data were statistically analyzed. Findings were correlated with circulating levels of LH, FSH, estradiol and progesterone. RIA revealed that the concentration of LH, FSH, estradiol and progesterone were significantly different with respect to hyperstimulation and mating. In addition the area occupied by LH and FSH cells was significantly different with respect to both hyperstimulation and mating. Hyperstimulation affects gonadotroph content, as well as gonadotropin and sex steroid hormone concentrations and together with other factors, may disrupt the ideal environment required for implantation. (+info)

Is there a difference in the function of granulosa-luteal cells in patients undergoing in-vitro fertilization either with gonadotrophin-releasing hormone agonist or gonadotrophin-releasing hormone antagonist? (4/1572)

Gonadotrophin-releasing hormone (GnRH) regulates gonadotrophin release. It has been shown that GnRH may have a direct effect on the ovary, as the addition of GnRH to granulosa cell cultures inhibits the production of progesterone and oestradiol. Specific GnRH receptors have been found to be present in rat and human granulosa cells. Desensitization of the pituitary by GnRH agonist has become common in in-vitro fertilization (IVF) treatment, usually by a long protocol of 2-3 weeks. With the introduction of GnRH antagonists, which produce an immediate blockage of the GnRH receptors, a much shorter exposure is needed of 3-6 days. The aim of this study was to evaluate the effect of a GnRH agonist (buserelin) and a GnRH antagonist (cetrorelix) on the function of granulosa cells cultured in vitro from IVF patients. Women were treated by IVF randomized either to have buserelin nasal spray from the luteal phase in the previous cycle or cetrorelix from day 6 of the cycle. Both groups had ovarian stimulation with human menopausal gonadotrophin (HMG) 150 IU daily, i.e. HCG was administered when the follicles were larger than 17 mm, and aspirated 36 h later. Granulosa cells, separated and washed from large follicles containing ova, were pooled. After 48 h of pre-incubation, the granulosa cells were cultured for 4 days in medium with either added testosterone or cAMP with or without HCG, with change of medium after 2 days. The progesterone and oestradiol concentrations in the culture medium were measured by immunological assay, and cellular protein was measured by microprotein assay. The results showed that granulosa cells from women treated with GnRH antagonist (cetrorelix) responded earlier to the in-vitro hormone stimulation in terms of progesterone accumulation than women treated with the GnRH agonist (buserelin). This may have been due to difference in time of exposure to the analogue. The results may indicate that the luteal function is less impaired in GnRH antagonist treatment than in GnRH agonist treatment. (+info)

Pharmaco-economic aspects of in-vitro fertilization in Italy. (5/1572)

Given the higher efficacy of follitropin-beta, a new recombinant follicle stimulating hormone (r-FSH), versus urinary-FSH (u-FSH), the present study was carried out to evaluate the cost-effectiveness ratio (CER) of follitropin-beta in comparison with u-FSH in women undergoing in-vitro fertilization (IVF) in Italy. Clinical decision analysis techniques were used to retrospectively model the direct medical costs of women undergoing IVF treatment. Seven Italian experts were interviewed, using a semi-structured questionnaire, in order to adapt the results of all clinical trials to the Italian patterns of care. Three analyses were conducted considering the public, the private sectors and a mixture of them (currently representing the Italian situation). The estimated total cost of IVF treatments varies from 106.9 and 211.7 billion Lire (63.2 and 125.2 million US$) depending on setting and type of treatment. The average CER varies from 21.5 and 37.7 million Lire (12, 700 and 22,300 $US) in the different hypotheses considered. The incremental CER varies from 19.2 and 26.0 million Lire (11,300 and 15,400 $US) depending on setting and type of treatment. (+info)

Poor responders to ovulation induction: is proceeding to in-vitro fertilization worthwhile? (6/1572)

A 'poor response' in the context of in-vitro fertilization (IVF) can be defined as failure to produce an adequate number of mature follicles, and/or a peak oestradiol concentration less than a defined minimum. The cut-off points implied in this definition vary between different centres. Many opt to cancel the IVF cycle when their defined minimum concentrations are not reached despite the lack of evidence of improved outcome in subsequent cycles. Patients attending the Oxford Fertility Unit who are 'poor responders' have always been given the option of continuing with treatment. The first cycles of IVF in 124 patients, with normal day 3 follicle stimulating hormone (FSH), who produced less than five follicles within a 2 year period were studied. The patients were divided into three groups according to the number of follicles produced: A (one or two follicles; n = 33), B (three follicles; n = 33) and C (four follicles; n = 58). The three groups were similar in age, day 3 FSH, total gonadotrophin dose, duration of stimulation, peak oestradiol concentration, oocyte yield, fertilization rate and the clinical pregnancy rate. However, group A had a significantly higher oestradiol concentration per follicle (P < 0.001). The clinical pregnancy rate/cycle in the three groups was comparable to our overall rate in the study period (25.5%). This paper suggests that poor responders with a normal day 3 FSH may still achieve a pregnancy rate similar to that of normal responders. (+info)

A prospective, randomized, double-blind clinical trial to study the efficacy and efficiency of a fixed dose of recombinant follicle stimulating hormone (Puregon) in women undergoing ovarian stimulation. (7/1572)

A prospective, randomized, double-blind, multicentre (n = 5) study was conducted to compare the influence of either a 100 or 200 IU daily fixed-dose regimen of recombinant follicle stimulating hormone (FSH) on the number of oocytes retrieved and the total dose used in down-regulated women undergoing ovarian stimulation. Fertilization was done by intracytoplasmic sperm injection or conventional in-vitro fertilization. A total of 199 women were treated with FSH, 101 subjects with 100 IU and 98 subjects with 200 IU. In subjects of the 200 IU treatment group, significantly more oocytes were retrieved compared to the 100 IU group (10.6 versus 6.2 oocytes, P < 0.001). The total dose needed to develop at least three follicles with a diameter of > or = 17 mm was significantly lower in the 100 IU treatment group (1114 IU versus 1931 IU, P < 0.001). In the low-dose group, significantly lower serum concentrations of oestradiol, progesterone and FSH were observed at the day of human chorionic gonadotrophin administration. Although more cycle cancellations due to low response were seen in the 100 IU group (n = 24 versus n = 3), the clinical pregnancy rate per started cycle was similar (24.7% in the 100 IU group versus 23.3% in the 200 IU group). In the high-dose group, more side-effects, in particular more cases of ovarian hyperstimulation syndrome, were noted. It is concluded that compared to 200 IU, the use of a 100 IU fixed dose is less efficacious in terms of the number of oocytes retrieved, but more efficient as indicated by a lower total dose. (+info)

Sperm treatment with extracellular ATP increases fertilization rates in in-vitro fertilization for male factor infertility. (8/1572)

Previous work from our laboratory has revealed that extracellular ATP is a rapid and potent activator of human sperm acrosome reaction and fertilizing ability. In the present study, we assessed the effects of in-vitro sperm incubation with ATP on fertilization and embryo development in couples undergoing in-vitro fertilization (IVF) for male factor infertility. Oocytes from 22 women undergoing ovulation induction were divided in two groups and inseminated in vitro either with selected spermatozoa from the corresponding partner suffering from male factor infertility pre-incubated with ATP (2.5 mM) for 1 h, or with spermatozoa incubated with 0.9% NaCl solution (control group). After insemination, fertilization was assessed by the presence of pronuclei and then by embryo cleavage. The fertilization rate in the group of oocytes inseminated with ATP-treated spermatozoa improved significantly with respect to the control group (65.7 versus 42.5%, P < 0.01). No significant differences were observed in embryo cleavage and embryo quality. Embryos from both treated and control groups were transferred together in 20 transfer procedures, and in two couples fertilization was not obtained. Nine pregnancies occurred: one biochemical, one miscarriage, and seven patients delivered 9 healthy babies. Two pregnancies were twin with an overall pregnancy rate of 40.9% per cycle and of 45% per transfer. In conclusion, the results of the present study demonstrate that, in humans, extracellular ATP induces a significant increase of sperm fertilizing potential, as these findings are a rationale for the use of ATP for in-vitro treatment of human spermatozoa during IVF. (+info)

HCG Injection After Ovulation Induction With Clomiphene Citrate at Medscape. By Peter Kovacs. Posted: 04/23/2004 IVF.com ... In the presence of one or more mature ovarian follicles, ovulation can be triggered by the administration of HCG. As ovulation ... Ovulation Induction. Retrieved Mars 7, 2010 Talwar GP, Gupta JC, Rulli SB, Sharma RS, Nand KN, Bandivdekar AH, Atrey N, Singh P ... Because of its similarity to LH, hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone ...

https://en.wikipedia.org/wiki/Human_chorionic_gonadotropin

van Wely M, Yding Andersen C, Bayram N, van der Veen F (2005). "Urofollitropin and ovulation induction". Treatments in ... Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and ...

https://en.wikipedia.org/wiki/Urofollitropin

Step by Step Ovulation Induction. Anshan Ltd, Kent, United Kingdom. ISBN 1-904798-96-9. Page 44. Follicle Stimulating Hormone ... antibodies generated in goats treated with eCG for the induction of ovulation modulate the luteinizing hormone and follicle- ... used therapeutically mainly as fertility medication for ovarian hyperstimulation and ovulation induction. For example, the so- ... Typically a single injection of 10,000 international units is used to induce ovulation. In men: Used to treat select cases of ...

https://en.wikipedia.org/wiki/Gonadotropin_preparations

Ghumman S (2006). Step by Step Ovulation Induction. Kent UK: Anshan. p. 134. ISBN 978-1-904798-96-5. Navot D, Rosenwaks Z, ... "Successful pregnancy in a 42-year-old woman with imminent ovarian failure following ovulation induction with ethinyl estradiol ... In the control group there were no ovulations. The patients ranged in age between 24 and 39 years with an average age of 32.7. ... Whereas nafarelin acetate in a nasal spray induces a short lived LH surge that is high enough to induce ovulation in large ...

https://en.wikipedia.org/wiki/Poor_ovarian_reserve

23-. ISBN 978-1-351-78989-9. Deshpande H (12 February 2016). Practical Management of Ovulation Induction. JP Medical Ltd. pp. ... on induction of menstruation, inhibition of nidation, and termination of pregnancy in bonnet monkeys". Biology of Reproduction ...

https://en.wikipedia.org/wiki/Lilopristone

Tanbo T, Mellembakken J, Bjercke S, Ring E, Åbyholm T, Fedorcsak P (October 2018). "Ovulation induction in polycystic ovary ... Sharpe A, Morley LC, Tang T, Norman RJ, Balen AH (December 2019). "Metformin for ovulation induction (excluding gonadotrophins ... for ovulation induction in infertile women with polycystic ovary syndrome". The Cochrane Database of Systematic Reviews. 2022 ( ... "Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline". Fertility ...

https://en.wikipedia.org/wiki/Polycystic_ovary_syndrome

ISBN 978-0-443-04514-1. Josef Blankstein; Shlomo Mashiach; Bruno Lunenfeld (1 July 1986). Ovulation Induction and in Vitro ... medication which is used as a gonadotropin stimulant or ovulation inducer and in menopausal hormone therapy in women. It is ... effects on the hypothalamic-pituitary-gonadal axis and hence can increase sex hormone production and stimulate ovulation. ...

https://en.wikipedia.org/wiki/Cyclofenil

Greenblatt, R., & Mahesh, V. (1965). Induction of Ovulation with Clomiphene Citrate. In T. Schwartz, Yearbook of Endocrinology ... Induction of Ovulation with MRL/41. JAMA, 178, 101. Greenblatt, R., Mahesh, V., & Jungck, E., Roy S. (1963). Clomiphene Citrate ... Further Observations on Its Use in Induction of Ovulation in the Human and Its Mode of Action. Fertility and Sterility, 14, 575 ... His group's discovery in 1961 that clomiphene citrate could induce ovulation was a breakthrough in reproductive biology, and ...

https://en.wikipedia.org/wiki/Robert_Benjamin_Greenblatt

The NSAI, letrozole is also used for ovulation induction in women with polycystic ovary syndrome (PCOS). Generally, clomiphene ... Holzer, Hananel; Casper, Robert; Tulandi, Togas (2006-02-01). "A new era in ovulation induction". Fertility and Sterility. 85 ( ... ISBN 3-7643-7199-4. Kar, Sujata (2013-04-01). "Current evidence supporting "letrozole" for ovulation induction". Journal of ... Letrozole seems to be just as effective as clomiphene citrate for ovulation and pregnancy rate as it has shown to be very ...

https://en.wikipedia.org/wiki/Non_steroidal_aromatase_inhibitors

Kistner RW (December 1965). "Induction of ovulation with clomiphene citrate (clomid)". Obstet Gynecol Surv. 20 (6): 873-900. ... "Induction of ovulation with clomiphene citrate (clomid)" "Histological effects of progestins on hyperplasia and carcinoma in ...

https://en.wikipedia.org/wiki/Robert_Kistner

1958, First report using pituitary FSH 1960, "An immunological pregnancy test" 1962, "Induction of ovulation with human ... Gemzell, C. A. (1962). "Induction of ovulation with human pituitary gonadotrophins". Fertility and Sterility. 13 (2): 153-68. ... Ovulation stimulation using FSH medication became the basis of modern infertility therapy such as IVF. First pregnancies were ... was the first to show that extracted gonadotropins containing FSH could be used as fertility medication to stimulate ovulation ...

https://en.wikipedia.org/wiki/Carl_Axel_Gemzell

Artificial induction of ovulation and in vitro fertilization-embryo replacement can also give rise to fraternal and identical ... "Increased Monozygotic Twinning Rate After Ovulation Induction". The Lancet. 329 (8544): 1236-1238. doi:10.1016/S0140-6736(87) ...

https://en.wikipedia.org/wiki/Twin_study

Weiss NS, Kostova E, Nahuis M, Mol BW, van der Veen F, van Wely M (January 2019). "Gonadotrophins for ovulation induction in ... However, ovulation induction remains an off-label indication, which affects use. Gonadotropins are protein hormones that ... Final maturation induction of follicles, also triggering a predictable time of ovulation. Either gonadotropin-releasing hormone ... The main techniques involving fertility medication in females are: Ovulation induction, with the aim of producing one or two ...

https://en.wikipedia.org/wiki/Fertility_medication

Gautam Allahbadia (29 February 2016). Manual of Ovulation Induction & Ovarian Stimulation Protocols. JP Medical Ltd. pp. 94-. ...

https://en.wikipedia.org/wiki/Medrogestone

Kovacs, P (2004). "HCG injection after ovulation induction with clomiphene citrate". Medscape. Retrieved 2011-08-01. Oyawoye OA ... Injection of hCG as a trigger for ovulation confers a risk of ovarian hyperstimulation syndrome, especially in women with ... When the ovarian follicles have reached a certain degree of development, induction of final oocyte maturation is performed, ...

https://en.wikipedia.org/wiki/Transvaginal_oocyte_retrieval

Ovulation Induction: using substances known as ovulation inductors. Semen capacitation: wash and centrifugation, swim-up, or ... To increase the chance of success, the woman's menstrual cycle is closely observed, often using ovulation kits, ultrasounds or ... there is no control of how many oocytes are at the same time when stimulating ovulation. For that reason, it is necessary to ... and viability of the male's sperm and the success of the female's ovulation. From these tests, the doctor may or may not ...

https://en.wikipedia.org/wiki/Artificial_insemination

"Studies on fixed-time ovulation induction in the pig". Soc Reprod Fertil Suppl. 66: 187-95. PMID 19848281. A. Labhart (6 ...

https://en.wikipedia.org/wiki/Metallibure

The Edinburgh unit was the second in the world to use human gonadotrophins for ovulation induction in humans but Brown, later ... Thornton, S.J., Pepperell, R.J., & Brown, J.B. (1990). Home monitoring of gonadotropin ovulation induction using the Ovarian ... Monitoring Induction of Ovulation by Rapid Radioimmunoassays of Oestrogen and Pregnanediol Glucuronides. Annals of Clinical ... contributions made by Brown in his early days in Edinburgh was the use of human gonadotrophin for the induction of ovulation. ...

https://en.wikipedia.org/wiki/James_Boyer_Brown

Ovulation induction (in the sense of medical treatment aiming for the development of one or two ovulatory follicles) is an ... HCG Injection After Ovulation Induction With Clomiphene Citrate at Medscape. By Peter Kovacs. Posted: 23 April 2004 Humaidan P ... In women with anovulation, it may be an alternative after 7-12 attempted cycles of ovulation induction, since the latter is ... Progesterone elevation on the day of induction of final maturation is associated with lower pregnancy rates in IVF cycles in ...

https://en.wikipedia.org/wiki/In_vitro_fertilisation

"Induction of Ovulation in the Human with Human Gonadotropins: Preliminary Report." Obstetrical & Gynecological Survey Buxton, C ... "Timing of Ovulation." American Journal of Obstetrics & Gynecology Buxton, C. Lee. (1956). "Human Infertility." Gynecology & ...

https://en.wikipedia.org/wiki/C._Lee_Buxton

February 1997). "Strategies for ovulation induction and oocyte retrieval in the lowland gorilla". Journal of Assisted ...

https://en.wikipedia.org/wiki/Western_lowland_gorilla

... is used for ovulation induction to treat infertility in women with anovulatory disorders. It is given at days three ... Steiner AZ, Terplan M, Paulson RJ (June 2005). "Comparison of tamoxifen and clomiphene citrate for ovulation induction: a meta- ... This compound was originally created to work as an estrogen inhibitor, but instead was found to stimulate ovulation in ... September 2007). "Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts". Cell. ...

https://en.wikipedia.org/wiki/Tamoxifen

Fowler and Edwards worked together on controlled ovulation induction in the mouse. In their first joint paper, published in ... Induction of superovulation and pregnancy in mature mice by gonadotrophins. J. Endocrinol. 15, 374-384. Gardner, Sir Richard ( ... FOWLER, R. E., & Edwards, R. G. (1957). Induction of superovulation and pregnancy in mature mice by gonadotrophins. Journal of ...

https://en.wikipedia.org/wiki/Ruth_Fowler_Edwards

391-. ISBN 978-3-88763-075-1. Maia H, Barbosa I, Maia H, Nascimento AJ, Bonfim de Souza M (1980). "Induction of ovulation with ... It has been used as a component of ovulation induction in combination with gonadotropin-releasing hormone. List of estrogens G. ...

https://en.wikipedia.org/wiki/Epimestrol

It can be combined with for example in vitro fertilization and ovulation induction. Progesterone appears to be the best method ... "Progesterone luteal support after ovulation induction and intrauterine insemination: an updated systematic review and meta- ...

https://en.wikipedia.org/wiki/Luteal_support

"Premature ovarian failure-the prognostic application of autoimmunity on conception after ovulation induction". Fertility and ... sites are free and treatment with exogenous recombinant FSH activates the receptors and normal follicle growth and ovulation ...

https://en.wikipedia.org/wiki/Primary_ovarian_insufficiency

For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the ... For patients who do not respond to diet, lifestyle modification and ovulation induction, in vitro fertilisation can be ... Methods that confirm ovulation may be used to evaluate the effectiveness of treatments to stimulate ovulation.[citation needed ... for ovulation induction in infertile women with polycystic ovary syndrome". The Cochrane Database of Systematic Reviews. 9: ...

https://en.wikipedia.org/wiki/Infertility_in_polycystic_ovary_syndrome

... predictability of intermittent ovarian function and response to ovulation induction agents". Current Opinion in Obstetrics & ... ready to be released during ovulation. The process of development from a primordial follicle to a pre-ovulatory follicle is ... and progesterone for at least a month in order to suppress their gonadotrophin levels which has been shown to promote ovulation ...

https://en.wikipedia.org/wiki/Ovarian_follicle_activation

The advantages of the procedure also include its singular treatment, as opposed to several trials of ovulation inductions. ... Laparoscopic ovarian drilling (LOD) may improve the effectiveness of other ovulation induction treatments and results in lower ... "Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome". The Cochrane ... Ovarian drilling is a surgical alternative to CC treatment or recommended for women with WHO Group II ovulation disorders. ...

https://en.wikipedia.org/wiki/Ovarian_drilling

In some cases, it is used in ovulation induction for reversal of anovulation as well. FSH is available mixed with LH activity ... The mean values for women before ovulation are around (3.8-8.8) mUI/mL. After ovulation these levels drop to between (1.8-5.1) ... This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase ... FSH levels in this time is often called basal FSH levels, to distinguish from the increased levels when approaching ovulation. ...

https://en.wikipedia.org/wiki/Follicle-stimulating_hormone

Mice are polyestrous and breed year round; ovulation is spontaneous. The duration of the estrous cycle is 4-5 days and lasts ... the American Veterinary Medical Association issued new guidelines for CO2 induction, stating that a flow rate of 10% to 30% ...

https://en.m.wikipedia.org/wiki/Laboratory_mouse

Sometimes a woman may be uncertain of the date of her last menstrual period, or there may be reason to suspect ovulation ... the risk of failing to recognize multiple gestations and can improve pregnancy dating to reduce the risk of labor induction for ... approximately 3 weeks after ovulation). The embryo should be seen by the time the gestational sac measures 25 mm, about five- ... and assuming ovulation occurred on day fourteen of the menstrual cycle. ...

https://en.wikipedia.org/wiki/Obstetric_ultrasonography

Uses include: Temporary suppression of fertility in female dogs Induction of ovulation in mares Gonadotropin-releasing hormone ... Final maturation induction after having performed controlled ovarian hyperstimulation. Usage of GnRH agonist for this purpose ... GnRH agonists are useful in: Suppression of spontaneous ovulation as part of controlled ovarian hyperstimulation, which is an ... GnRH agonist for that purpose as well inactivates the axis for which it is intended to work for final maturation induction. ...

https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone_agonist

Ovulation induction can be achieved either with pulsatile GnRH therapy or alternatively with gonadotropin injections (hCG, FSH ... Dunkel L, Quinton R (June 2014). "Transition in endocrinology: induction of puberty". European Journal of Endocrinology. 170 (6 ... can also be used in male patients to induce secondary sexual characteristic development alongside possible fertility induction ...

https://en.wikipedia.org/wiki/Kallmann_syndrome

In terms of ovulation inhibition, the effective dosage of CPA is 1.0 mg/day while that of medroxyprogesterone acetate is 10 mg/ ... Induction by an estrogen-progesterone synergy". Steroids. 38 (3): 321-331. doi:10.1016/0039-128X(81)90067-2. ISSN 0039-128X. ... Based on ovulation inhibition, a dosage of 50 mg/day cyproterone acetate has on the order of 200 times the progestogenic ... Endrikat J, Gerlinger C, Richard S, Rosenbaum P, Düsterberg B (December 2011). "Ovulation inhibition doses of progestins: a ...

https://en.wikipedia.org/wiki/Side_effects_of_cyproterone_acetate

Oliveira, R.G., Tomasi, L., Rovasio, R.A. and Giojalas, L.C. (1999) Increased velocity and induction of chemotactic response in ... to compensate for the lack of coordination between insemination and ovulation. In humans, there are at least two different ...

https://en.wikipedia.org/wiki/Sperm_chemotaxis

Induction into the Minnesota Science and Technology Hall of Fame Knight Grand Cross of the Order of the Holy Sepulchre of ... Mary's University Distinguished Alumnus "Transient Distortion in Loudspeakers", May-June 1961 "Ovulation Detection by Internal ... Adducci A, Weidenkopf TE, Garwacki DJ (1965). "Ovulation Detection by Internal Cranial Temperature Measurements". IEEE ... Adducci worked with a local physician and developed an electronic ear thermometer used to detect the time of ovulation in the ...

https://en.wikipedia.org/wiki/Anthony_Adducci

The main ovulation induction medications include: Antiestrogen, causing an inhibition of the negative feedback of estrogen on ... For women with POI that desire pregnancy, ovulation induction strategies should be avoided and assisted reproduction, such as ... It is said to be the most reliable way of confirming whether ovulation has occurred. Women may also use ovulation predictor ... and increased physical activity can re-establish spontaneously ovulation and improve response to ovulation induction therapy if ...

https://en.wikipedia.org/wiki/Anovulation

Skidmore, J. A.; Billah, M.; Allen, W. R. (1 March 1996). "The ovarian follicular wave pattern and induction of ovulation in ... In another study, ovulation could be best induced when the follicle reaches a size of 0.9-1.9 cm (0.35-0.75 in). In another ... Chen, B.X., Yuen, Z.X. and Pan, G.W. (1985). "Semen-induced ovulation in the bactrian camel (Camelus bactrianus)". J. Reprod. ...

https://en.wikipedia.org/wiki/Dromedary

Induction of oestrus in anoestrus cows. Treatment of follicular cysts Persistent ovarian follicles Improve oocyte quality ... A dominant follicle develops but there is no ovulation as LH release is prevented by suppression of GnRH. Removal of ... 1983). Multiple use of progesterone releasing intravaginal devices for synchronisation of oestrus and ovulation in cattle. ... progesterone device produces a surge of GnRH, generating a pulse of LH that induces ovulation. Progesterone Releasing ...

https://en.wikipedia.org/wiki/Progesterone_devices_used_in_farm_animals

... of his other contributions included advancing embryo transfer technology and development of cost-effective ovulation induction ...

https://en.wikipedia.org/wiki/Baidyanath_Chakrabarty

The drug was also evaluated for the purpose of ovulation induction and as a treatment of chronic mastitis and endometrial ...

https://en.wikipedia.org/wiki/Ethamoxytriphetol

Exposure to nitrogen dioxide causes ovulation-induced oxidative damage to the DNA of ovarian epithelium. There is a growing ... oligomerization of GSTP and induction of the JNK pathway, resulting in apoptosis or inflammation of the bronchioles and ...

https://en.wikipedia.org/wiki/Nitrogen_dioxide_poisoning

Caesareans or inductions are advised after 38 weeks of pregnancy for twins, because the risk of stillbirth increases after this ... O. Bomsel-Helmreich; W. Al Mufti (1995). "The mechanism of monozygosity and double ovulation". In Louis G. Keith; Emile ...

https://en.wikipedia.org/wiki/Twin

... as a regular contraceptive at 2 mg daily prevents ovulation (1 mg daily does not). A single preovulatory 10-mg ... when followed by a prostaglandin analog Cervical softening and dilation prior to first trimester surgical abortion Induction of ... dose of mifepristone delays ovulation by three to four days and is as effective an emergency contraceptive as a single 1.5-mg ...

https://en.wikipedia.org/wiki/Mifepristone

Around half of women with epilepsy who menstruate have a lowered seizure threshold around ovulation, most likely from the ... Ottosson UB, Carlström K, Johansson BG, von Schoultz B (1986). "Estrogen induction of liver proteins and high-density ... The contraceptive effects of estrogens are mediated by their antigonadotropic effects and hence by inhibition of ovulation. ... Estrogens mediate their contraceptive effects in combination with progestins by inhibiting ovulation. Estrogens were first ...

https://en.wikipedia.org/wiki/Estrogen_(medication)

Guraya S. S., Dhanju C. K. (November 1992). "Mechanism of ovulation--an overview". Indian J Exp Biol. 30 (11): 958-967. PMID ... Dhindsa J. S.; Sidhu K. S.; Guraya S. S. (September 1995). "Induction of buffalo (Bubalus bubalis ) sperm capacitation and ...

https://en.wikipedia.org/wiki/Sardul_Singh_Guraya

On the other hand, the induction or repression of the expression of genes requires the binding of transcriptional factors to ... During meiotic maturation, the LH peak that precedes ovulation activates MAPK pathway leading to gap junction disruption and ... Ying, QL; Nichols, J; Chambers, I; Smith, A (31 October 2003). "BMP induction of Id proteins suppresses differentiation and ... Kim, J; Bagchi, IC; Bagchi, MK (December 2009). "Control of ovulation in mice by progesterone receptor-regulated gene networks ...

https://en.wikipedia.org/wiki/Biochemical_cascade

Total number of ovulation in all subjects: 30. % of ovulation in all subjects: 49. Milan Rastislav Henzl; John A. Edwards (10 ... Ottosson UB, Carlström K, Johansson BG, von Schoultz B (1986). "Estrogen induction of liver proteins and high-density ... did not prevent ovulation in all cases. Schacter L, Rozencweig M, Canetta R, Kelley S, Nicaise C, Smaldone L (March 1989). " ... As indexes of the occurrence of ovulation, daily basal temperatures and vaginal smears were taken, and at the nineteenth to ...

https://en.wikipedia.org/wiki/Progestogen_(medication)

Ovulation Induction Archived 2009-10-03 at the Wayback Machine Retrieved on Mars 7, 2010 fertilityLifeLines > Ovulation ... Ovulation induction is usually used in the sense of stimulation of the development of ovarian follicles by fertility medication ... Ovulation Problems and Infertility: Treatment of ovulation problems with Clomid and other fertility drugs. Advanced Fertility ... an injection of the hormone hCG initiates the ovulation process. Egg retrieval should occur from 34 to 36 hours after the hCG ...

https://en.wikipedia.org/wiki/Assisted_reproductive_technology

... ovulation induction MeSH E02.875.800.984.500 - superovulation MeSH E02.875.800.992 - zygote intrafallopian transfer MeSH ... ovulation inhibition MeSH E02.875.194.910 - sterilization, reproductive MeSH E02.875.540.515 - insemination, artificial, ...

https://en.wikipedia.org/wiki/List_of_MeSH_codes_(E02)

Ovulation Induction Archived 2013-03-10 at the Wayback Machine Retrieved on Mars 7, 2010 IVF.com > Ovulation Induction Archived ... "Ovulation Induction". Manchester University. Retrieved 2019-04-04. Ovulation Problems and Infertility: Treatment of ovulation ... Ovulation induction is the stimulation of ovulation by medication. It is usually used in the sense of stimulation of the ... The term ovulation induction can potentially also be used for: Final maturation induction, in the sense of triggering oocyte ...

https://en.wikipedia.org/wiki/Ovulation_induction

We are considering the use of CPT code 99211 for encounters during cycle management as part of ovulation induction. Nursing ... Monitoring Ovulation Induction By Nurses We are considering the use of CPT code 99211 for encounters during cycle management as ... part of ovulation induction. Nursing staff meets with the patient after ultrasounds are performed and blood work is drawn. ...

https://www.asrm.org/resources/coding/coding-qa/coding-corner/monitoring-ovulation-induction-by-nurses/

Recombinant versus urinary human chorionic gonadotrophin for ovulation induction in assisted reproduction. Review question ...

https://www.cochrane.org/CD003719/MENSTR_recombinant-versus-urinary-human-chorionic-gonadotrophin-ovulation-induction-assisted-reproduction

Ovulation Induction. The principle of ovulation induction is to obtain more than one egg by stimulating the ovaries that ...

https://www.bebekistiyorum.com/ivf/treatment-methods/ovulation-induction.233.4.aspx

Patient predictors for outcome of gonadotrophin ovulation induction in women with normogonadotrophic anovulatory infertility: a ... Ovulation Induction/*methods, Pregnancy, Reference Values, Research Support, Non-U.S. Govt, Treatment Outcome ... gonadotrophin ovulation induction outcome in normogonadotrophic women are obesity and insulin resistance. ... predict clinically significant outcomes of ovulation induction with gonadotrophins, and to obtain pooled estimates of their ...

https://repub.eur.nl/pub/10266

Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome.. Authors: Weerakiet, S. Srisombut, C. Choktanasiri, ... Weerakiet S, Srisombut C, Choktanasiri W, Rojanasakul A. Efficacy of laparoscopic ovulation induction in polycystic ovary ... After surgery, ovulation was documented in 16 out of 18 (88.9%) patients. Fifteen (71.4%) patients became pregnant. Fourteen ...

https://imsear.searo.who.int/handle/123456789/45010

Tag: ovulation induction. Anovulation and ovulation induction. Posted on September 11, 2018. August 23, 2022. by admin ...

https://www.hippokratia.gr/tag/ovulation-induction/

This is especially helpful for women with irregular periods, which is suggestive of a problem of ovulation, or egg release. ... These medications act to enhance a womans ovulation, and yield a 5-10 % per cycle pregnancy rate when combined with timed ...

https://www.hudsonvalleyfertility.com/ovulation-induction/

What is Ovulation and the things you need to know about your Ovulation Cycle?. Tags : Ovulation inductionOvulation induction ... Ovulation predictor kits (OPK): These kits are easily available over-the-counter (OTC) at any drugstore. The ovulation ... What is Ovulation and the things you need to know about your Ovulation Cycle?. *Home ... it has been found that most of the women are most fertile in the first five days before ovulation and on ovulation day itself. ...

https://fertilitycentrenepal.com/tag/ovulation-induction/

Course Name : Ovulation Induction Protocols in TI/IUI. The aim of this training program is to reinforce the need to have a full ... It also focuses on Case scenarios in ovulation induction.. Eligibility: MBBS, MS, OBG, MD, DGO. Certificate: Yes. At the end of ... understanding of ovulation induction in different patient profiles in basic. ART treatments. It gives an understanding of ...

https://osherm.com/courses/ovulation-induction-protocols-in-ti-iui/

Odem, R. R. / Concluding remarks : Exploring new frontiers in ovulation induction. In: American journal of obstetrics and ... Concluding remarks : Exploring new frontiers in ovulation induction. / Odem, R. R.. In: American journal of obstetrics and ... Odem, R. R. (1995). Concluding remarks: Exploring new frontiers in ovulation induction. American journal of obstetrics and ... Concluding remarks: Exploring new frontiers in ovulation induction. American journal of obstetrics and gynecology. 1995;172(2 ...

https://profiles.wustl.edu/en/publications/concluding-remarks-exploring-new-frontiers-in-ovulation-induction-2

Clomid for ovulation induction may be able to help you welcome a baby. Learn more from our Las Vegas infertility doctors. ... Clomid for ovulation induction can help you welcome a baby. Many patients who visit The Fertility Center of Las Vegas (FCLV) ... Then, the increased LH stimulates ovulation, which releases the egg or eggs. ... the next step is for you to take a trigger shot or use an ovulation kit. From there, treatment will either be timed intercourse ...

https://fertilitycenterlv.com/diagnosis-treatment-care/clomid/

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Ovulation induction helps reversing anovulation or oligoovulation, that is, helping women who do not ovulate on their own regularly, such as those with polycystic ovary syndrome (PCOS). (wikipedia.org)
Although there are certain things like stress or improper diet which can also impact the exact day of ovulation from month to month or there can be medical conditions as well like polycystic ovary syndrome (PCOS) or amenorrhea that may make woman's ovulation irregular or stop completely. (fertilitycentrenepal.com)
Citrate (cc) (100 mg) for ovulation induction in women with polycystic ovary syndrome. (bowencentersa.org)
IMSEAR at SEARO: Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome. (who.int)
Weerakiet S, Srisombut C, Choktanasiri W, Rojanasakul A. Efficacy of laparoscopic ovulation induction in polycystic ovary syndrome. (who.int)
First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. (bmj.com)
If you've ever come face to face with hormonal conditions that could have hampered your fertility, such as polycystic ovary syndrome, hypopituitarism or endometriosis, chances are, that your hormonal reserves need to be optimised through ovulation induction. (cloudninefertility.com)
Dr. Perloe has served as principal investigator in numerous reproductive health research studies including innovative IVF treatments, ovulation induction, and polycystic ovary syndrome. (prweb.com)

These medications act to enhance a woman's' ovulation, and yield a 5-10 % per cycle pregnancy rate when combined with timed intercourse or intrauterine insemination (IUI). (hudsonvalleyfertility.com)
When combined with fertility treatments like IVF and intrauterine insemination , ovulation induction can greatly improve your chances of successfully becoming pregnant and experiencing a live birth. (center4fertility.com)
Superovulation, or ovulation induction is the first stage in many fertility treatments including in vitro fertilization , intrauterine insemination , and egg donation . (center4fertility.com)
Intrauterine insemination (IUI) is a fertility treatment where a doctor inserts sperm directly into the uterus during ovulation. (ivfspecialists.com)
Infertility in women is often treated with oral ovulation induction medications such as Clomid and Femara, with or without intrauterine insemination. (samhealth.org)
DGFC provides specialised treatment with services such as intra-cytoplasmic sperm injection (ICSI), in vitro fertilization (IVF), testicular sperm aspiration (Tesa), percutaneous epididymal sperm aspiration (PESA), freezing of eggs and sperm, intrauterine insemination (IUI) , ovulation induction, gender selection, detection of genetic anomalies etc. (emirates247.com)

A systematic review was conducted to determine whether initial screening characteristics of women with normogonadotrophic anovulatory infertility predict clinically significant outcomes of ovulation induction with gonadotrophins, and to obtain pooled estimates of their predictive value through meta-analysis. (eur.nl)
Letrozole should be considered first line pharmacological treatment for ovulation induction in women with pcos with anovulatory infertility and no other. (bowencentersa.org)
These include the fact that infertility in itself is a known risk factor for some of these cancers, that these patients are subjected to increased surveillance compared to the general population and that the drugs used for ovulation induction are sometimes used in combination. (fvvo.eu)
Here are three ways undergoing ovulation stimulation at The Center for Fertility and Gynecology in Los Angeles, CA, can help you overcome infertility. (center4fertility.com)
This low intervention option is helpful when the cause of your infertility is unexplained, caused by a cervical factor, or due to irregular or absent ovulation. (oviahealth.com)
Rancic's fertility story and the stories of other high-profile women such as Liz Tilberis (the late editor-in-chief of Harper's Bazaar), Gilda Radner (Saturday Night Live comedienne), and author and activist Elizabeth Edwards -- all of whom died of either ovarian or breast cancer after multiple cycles of ovulation and induction - demonstrate the need for a more meaningful public debate about the nature and root causes of infertility. (vitalitymagazine.com)
Induction of ovulation and pregnancy in patients with functional anovulatory infertility without primary ovarian failure. (oncologynurseadvisor.com)
Published May 16, 2013 at 400 × 298 in Evaluation of Infertility, Ovulation Induction and Assisted Reproduction . (endotext.org)
There are many causes of infertility, including problems with ovulation (the release of an egg from a woman's ovary), fertilisation by a man's sperm and implantation of the fertilised egg into the lining of the woman's uterus. (yourhealth.net.au)
If your health care provider recommends this treatment, and if the first two or three attempts are unsuccessful, ask about a referral to a provider who specializes in infertility, such as myself, so the treatment may be closely monitored and fine-tuned to maximize changes of ovulation before more expensive and complex treatment options must be considered. (samhealth.org)
Pregnancies with multiple gestations are associated with serious infant and maternal health risks as well as psychological distress and significant financial consequences, and are a far too common consequence of infertility treatments such as assisted reproductive technology (ART) and ovulation induction drugs. (nursingcenter.com)

Letrozole for induction of ovulation in pcos patients: resistant to clomiphene citrate south asian federation of obstetrics and gynaecology. (bowencentersa.org)
Mechanism of letrozole action in ovulation induction (clomiphene citrate treatment). (bowencentersa.org)
Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/440164/all/Clomiphene_citrate_for_ovulation_induction_in_women_with_oligo_amenorrhoea:_Cochrane_systematic_review. (unboundmedicine.com)
After preconception intervention, women underwent standardized ovulation induction with clomiphene citrate and timed intercourse for four cycles. (nih.gov)
Clomiphene citrate (Clomid, Serophene) is a commonly used ovulation induction medication. (oviahealth.com)
First-line treatment for ovulation induction when fertility is desired are letrozole or clomiphene citrate. (medscape.com)
Clomiphene citrate is typically not effective for inducing ovulation in these patients. (medscape.com)
And we also use ovulation-induction agents like clomiphene citrate to bring on ovulation. (empowher.com)
E2 (suppositories) and progesterone to CC (clomiphene citrate) ovulation induction regimens normalizes the alterations in endometrial morphology. (bellaonline.com)
In summary, clomiphene citrate is a viable alternative for ovulation induction. (killtenrats.com)

Also, where anovulation or oligovulation is secondary to another disease, the treatment for the underlying disease can be regarded as ovulation induction, by indirectly resulting in ovulation. (wikipedia.org)
Flinders fertility offers cycle monitoring and ovulation induction (oi) with clomid, letrozole, or fsh injections for patients with anovulation. (bowencentersa.org)
Conditions like anovulation (absence of ovulation) and oligo-ovulation (irregular ovulation) prevent your ovaries from naturally releasing mature eggs in a regular, predictable cycle. (center4fertility.com)
Sporadic menstruation is usually induced by a hormonal disequilibrium, leading to anovulation or infrequent ovulation. (cloudninefertility.com)

1 Women with PCOS who are trying to conceive are sometimes prescribed clomiphene (Clomid,™ Serophene ® ), a fertility drug that stimulates ovulation. (herbalgram.org)
Research done on animals has shown some promise for fenugreek's potential role as a natural alternative to ovulation stimulant drugs such as Clomid. (sfgate.com)

Ovulation induction is the stimulation of ovulation by medication. (wikipedia.org)
Through advanced diagnostic tests, our doctors can determine whether ovulation stimulation is appropriate. (center4fertility.com)
Conclusive evidence on the correlation between fenugreek and ovulation stimulation is very difficult to find. (sfgate.com)

By definition, women with pcos do not spontaneously ovulate each month such that fertility treatments, specifically, ovulation induction, is. (bowencentersa.org)
Ovulation induction is the first step in most fertility treatments . (center4fertility.com)

We are also starting ovulation induction and in vitro fertilization cycles. (inviafertility.com)
Some of the most common assisted human reproductive technologies include ovulation induction, artificial insemination, in-vitro fertilization, donor conception, and surrogacy. (cwilson.com)
In vitro-fertilisering (IVF), eller provrörsbefruktning, är en fertilitetsmetod där en kvinnas ägg tas ut från en äggstock för att befruktas av en mans spermie utanför en kvinnas kropp ( in vitro ), i stället för i en kvinnas äggledare som efter ett samlag eller vid insemination, och därefter återföras till en livmoder In vitro fertilisation is the most common type of reproductive medicine treatment . (stammer-forsvann-nasta.com)
the biggest reason for the increased rate of premature newborns is the increase in women who are impregnated through in vitro fertilization and ovulation induction, practices that can double or triple the possibility of having twins or triplets. (californiahealthline.org)
In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)

Adult women with hypogonadotropic hypogonadism who desire fertility undergo ovulation induction with injectable gonadotropins. (medscape.com)

If ovulation is induced incorrectly, it could lead to a condition called ovarian hyperstimulation syndrome. (cloudninefertility.com)

Conclusion: tamoxifen should be the first choice to induce ovulation in anovulatory pco women. (bowencentersa.org)

Ovulation induction prepares at least one egg in every cycle to meet its potential suitor, the sperm. (cloudninefertility.com)

A medication called metformin treats diabetes and can also help improve menstrual cycles and ovulation in women with PCOS. (nih.gov)
Patients prescribed Letrozole or Clomiphene for ovulation induction have been advised to stop the medication immediately. (uhb.nhs.uk)
IUI can be done with a natural ovulation cycle or ovulation induction with medication. (ivfspecialists.com)
They also take a medication to prevent premature ovulation. (nashvillefertility.com)
During IUI and IVF cycles, while the woman is on medication for ovulation induction, it is important that the follicular growth be monitored by ultrasonography. (iwannagetpregnant.com)
A simple treatment that uses medication to stimulate the ovaries and encourage ovulation. (sunfert.com)

The term ovulation induction can potentially also be used for: Final maturation induction, in the sense of triggering oocyte release from relatively mature ovarian follicles during late follicular phase. (wikipedia.org)
Controlled ovarian hyperstimulation (stimulating the development of multiple follicles of the ovaries in one single cycle), has also appeared in the scope of ovulation induction. (wikipedia.org)
By increasing certain hormones in the body, the treatment triggers ovulation and increases the number of follicles that are available for harvesting. (center4fertility.com)
On Cloudnine, we monitor ovulation induction cycles continually through pelvic ultrasounds, to measure how well the follicles are developing and how thick the endometrium is growing. (cloudninefertility.com)
Patients with menstrual cycles longer than 30 days, irregular ovulation and menstruation, the production of more than 20 follicles, are all at higher risk. (goivf.com)

The principle of ovulation induction is to obtain more than one egg by stimulating the ovaries that usually produce only one egg cell. (bebekistiyorum.com)
Only those studies in which pre-treatment screening characteristics (such as body mass index, serum LH and androgens, insulin sensitivity and ultrasound appearance of ovaries) were related to outcome parameters (such as total amount of FSH administered, cancellation, ovulation, pregnancy and miscarriage), were included in this analysis. (eur.nl)
Ovulation is a process which happens usually once in every menstrual cycle in which hormone changes and ovaries are triggered to release an egg. (fertilitycentrenepal.com)
At the time of your ovulation each month one of your ovaries will release a mature egg, which will travel into one of the woman's fallopian tubes. (fertilitycentrenepal.com)
Polycystic ovarian syndrome (PCOS) - a hormonal endocrine disorder that affects more than 5 million women in the United States alone - manifests itself through a spectrum of symptoms, including irregular or absent menstruation (known as amenorrhea), lack of ovulation, multiple cysts on the ovaries, acne, excessive facial hair (hirsutism), and obesity. (herbalgram.org)

The LH surge causes the release of the mature egg from the woman ovary and this entire procedure is known as ovulation. (fertilitycentrenepal.com)
The impact of ovulation-inducing drugs not associated with an ART procedure was estimated by subtracting both ART-related births (from the SART reporting system) and spontaneously occurring triplet and higher-order multiple births ( 6 ) from the total number of these births. (cdc.gov)
Ovulation induction is an ideal procedure for women whose menstrual cycles do not follow a predictable pattern. (cloudninefertility.com)
Ovulation induction is a completely safe, non-invasive procedure, suited for most women with a yoyoing hormone graph. (cloudninefertility.com)
We know that a traditional ovulation induction procedure poses risks to a woman, of which some are mentioned below. (cloudninefertility.com)

A higher dose of up to 12.5 mg per day results in increased follicular growth and a higher number of predicted ovulations, without a detrimental effect on endometrial thickness, and is considered in those who do not respond adequately to a lower dose. (wikipedia.org)

This involves stimulating the woman's ovulation process through the use of oral medications and the regular injection of follicle-stimulating hormones like gonadotropin. (familyeducation.com)

The main alternatives for ovulation induction medications are: Antiestrogen, causing an inhibition of the negative feedback of estrogen on the pituitary gland, resulting in an increase in secretion of follicle-stimulating hormone. (wikipedia.org)
We incorporate medications and hormone therapy to induce ovulation. (center4fertility.com)
At the Center for Fertility and Gynecology in Los Angeles , we accomplish ovulation induction through the use of different medications and hormones. (center4fertility.com)
Ovulation induction using medications to improve ovulation. (yourhealth.net.au)
Ovulation induction medications. (nashvillefertility.com)
The egg donor self-administers ovulation induction medications to cause multiple eggs to mature. (nashvillefertility.com)

Severe ovarian hyperstimulation is a rare complication of ovulation induction therapy. (saudija.org)

5 mg) and anastrozole (1 mg) meant for ovulation induction in clomiphene (cc)-resistant women with pcos. (bowencentersa.org)
Surgical management of PCOS is aimed mainly at restoring ovulation. (medscape.com)
Women with PCOS who lose weight are more likely to have restored ovulation and improved pregnancy rates. (nih.gov)
Ovarian drilling is a surgical treatment that can stimulate ovulation in women with PCOS. (nih.gov)
Studies of women with PCOS have shown that ovarian drilling results in an 80% ovulation rate and a 50% pregnancy rate. (nih.gov)
Taking inositol by mouth seems to lower triglyceride levels , decrease blood pressure, and improve blood sugar , ovulation , and pregnancy rates in people with PCOS. (webmd.com)
Aside from helping women who have PCOS to lose weight, the keto diet can also help to rebalance the hormones, which is needed for ovulation. (shedandshape.com)

At this point, the couple were recommended Ovulation Induction treatment with a drug called Gonal F. Gonal F is a hormonal treatment given through a series of self-administered injections to stimulate ovulation. (tfp-fertility.com)

Then, the increased LH stimulates ovulation, which releases the egg or eggs. (fertilitycenterlv.com)

In conclusion, the best available evidence, though limited, suggests that the most clinically useful predictors of gonadotrophin ovulation induction outcome in normogonadotrophic women are obesity and insulin resistance. (eur.nl)
This is especially helpful for women with irregular periods, which is suggestive of a problem of ovulation, or egg release. (hudsonvalleyfertility.com)
The time when women approach ovulation her body starts producing an increased amount of hormone called estrogen. (fertilitycentrenepal.com)
The egg of the woman can only be fertilized for up to 24 hours after ovulation, however, if it is not fertilized after 24 hours of ovulation then the lining of the womb is shed which means the mature egg is lost and women period begins. (fertilitycentrenepal.com)
According to the study, it has been found that most of the women are most fertile in the first five days before ovulation and on ovulation day itself. (fertilitycentrenepal.com)
There are many cases where the cycle lengths vary and ovulation occurs 14 days prior to the women next period begins. (fertilitycentrenepal.com)
c) How women can track their ovulation time? (fertilitycentrenepal.com)
The fertility experts at Fertility Center Nepal suggest the best way for the women to confirm when she ovulates is with an ultrasound in the hospital or clinic, or also they can track their ovulation time with hormonal blood tests at home. (fertilitycentrenepal.com)
Ovulation is confirmed after the women temperature has stayed elevated from her baseline for three days. (fertilitycentrenepal.com)
The ovulation predictor kit will detect the presence of LH in the women urine and you will be able to ovulate within the next couple of days after the result line is as dark as the control. (fertilitycentrenepal.com)
If the women track her ovulation from one month to the next month and she will be able to notice that either she is not ovulating regularly or in some cases, they are not ovulating at all. (fertilitycentrenepal.com)
For women who do ovulate, ovulation induction can stimulate more eggs. (oviahealth.com)
Ovulation induction is a treatment commonly elected by women who experience irregular or absent ovulatory cycles. (cloudninefertility.com)
All the women had an endometrial biopsy ten days after ovulation. (bellaonline.com)
Avoid intercourse for women with significant ovarian enlargement after ovulation. (oncologynurseadvisor.com)
Women who undergo ovulation induction and with a Leading follicular size of 18mm or more in transvaginal ultrasound scan (TVS) c. (who.int)
The best thing about it is that two of the four women conceived spontaneously without the need for ovulation induction. (shedandshape.com)
In a study with more than 6,100 pregnant women across the country, researchers randomly assigned half of the women to an expectant management group (waiting for labor to begin on its own and intervening only if problems occur) and the other half to a group that would undergo an elective induction (inducing labor without a medical reason) at 39 weeks of gestation. (skepticalob.com)

If you haven't been able to gauge the beat of your ovulatory cycles, it's possible that your ovulation is infrequent or absent. (cloudninefertility.com)
Also, risk seems zero to minimal with less than 12 cycles of ovulation induction during IVF. (wdxcyber.com)

As part of your ovulation induction treatment cycle your doctor has prescribed either clomiphene or letrozole tablets or fsh injections to stimulate the. (bowencentersa.org)

Ovulation induction aims to open up frequent fertile windows, during which a schedule for intercourse is recommended. (cloudninefertility.com)
I have gone through 3 TSI's (stimulated/timed ovulation and intercourse) and started IVF two months ago but they cancelled it on me as my egg growth was too quick on one egg and the rest were too slow. (rollercoaster.ie)

Ovulation (release of on ovum by an ovary) during an ongoing pregnancy. (healthline.com)
Corpus Luteum - A special gland that forms on the surface of the ovary at the site of ovulation and produces progesterone during the second half of the cycle. (txfertility.com)

Ovulation induction lets you slip into a subtle programmed monthly cycle, allowing your body to replenish its hormone levels and resume ovulation. (cloudninefertility.com)
Fenugreek also contains phytoestrogens, compounds that act like the hormone estrogen, one of the hormones regulating ovulation. (sfgate.com)
Once the eggs are sufficiently grown as per the scan and hormone tests, you will receive injection Hcg as an ovulation trigger. (nufertility.com)

The goal of this treatment is exactly what the name implies: to induce ovulation when it's absent or irregular. (oviahealth.com)

Also, Gonal-F: Induction of spermatogenesis in men with hypogonadotropic hypogonadism without primary testicular failure. (oncologynurseadvisor.com)

The hormonal support consisted of estradiol suppositories (E2) 0.1 mg twice a day from day eight until the LH surge followed by progesterone gel applied close to the uterus as directed beginning three days after ovulation. (bellaonline.com)
Ovulation was induced in three of four hCG-treated mares that also developed prolonged luteal phases, as assessed by progesterone analysis. (slu.se)
The rats given fenugreek extract seemed to show significant elevation of estrogen and progesterone, two hormones crucial in inducing ovulation. (sfgate.com)
Progesterone helps the production of estrogen, and both hormones are necessary in adequate supply for ovulation to occur. (sfgate.com)

However, thanks to Ovulation Induction treatment, they are now besotted parents to daughter Tiggy and baby son Radley. (tfp-fertility.com)
Increasingly conscious of the four attempts of Ovulation Induction advised by Dr Ingamells, the couple embarked on their fourth round of treatment. (tfp-fertility.com)
Objetive: to compare the efficacy of letrozole vs. Treatment with letrozole for ovulation induction is off-licence as the drug company has not applied for a specific license to allow. (bowencentersa.org)
If you have been considering IVF , egg freezing , or another type of fertility treatment and would like to learn more about ovulation induction, reach out to our Los Angeles, CA, office. (center4fertility.com)
Ovulation induction is composed of a string of steps, which are seamlessly sewn together to create a treatment plan. (cloudninefertility.com)
In addition, since treatment with progestins to suppress oestrous cyclicity in competition mares is not endorsed by most European Community countries, a preliminary study was performed to determine if dioestrous ovulations and a subsequent prolonged luteal phase can be induced using human chorionic gonadotropin (hCG). (slu.se)

On the contrary, many studies suggest that drugs used for ovulation induction may increase the risk of uterine cancers. (fvvo.eu)
In the United States, pregnancies associated with assisted reproductive technology (ART) or ovulation-inducing drugs are more likely to result in multiple births than spontaneously conceived pregnancies ( 1 ). (cdc.gov)
This report provides estimates of the contribution of ART and ovulation-inducing drugs to these birth outcomes for 1996 and 1997, and summarizes trends during 1980--1997, which indicate that the ratio of triplet and higher-order multiple births has more than quadrupled and that a large proportion of this increase can be attributed to ART or the use of ovulation-inducing drugs. (cdc.gov)
this trend began after the Food and Drug Administration approved two ovulation-inducing drugs, one in 1967 and another in 1970. (cdc.gov)
For both years, approximately 20% were attributable to spontaneously occurring triplets and higher-order multiple births and approximately 40% were attributable to ovulation-inducing drugs without ART. (cdc.gov)
Perinatal risk factors that have a suggested association include β 2 adrenergic receptor agonists, labor induction and augmentation, maternal infection and disease (i.e., antiphospholipid syndrome), antiepileptic drugs, cocaine use, and oral supplements. (hindawi.com)
Ovulation can be induced either through oral drugs or through injectables. (medtalks.in)

Odem, RR 1995, ' Concluding remarks: Exploring new frontiers in ovulation induction ', American journal of obstetrics and gynecology , vol. 172, no. 2 II, pp. 792. (wustl.edu)
Dr. Kaberi Banerjee, Medical Director, Advanced Fertility & Gynecology Center, New Delhi will discuss how to induce ovulation in this video. (medtalks.in)

A preconception weight loss intervention eliminates the adverse metabolic oral contraceptive effects and, compared with oral contraceptive pretreatment, leads to higher ovulation rates. (nih.gov)

Given that the administration of hCG appears to be the precipitating event for developing OHSS, an alternative to hCG induced ovulation triggering (such as GnRH agonist or Lupron) can avoid the risk of OHSS. (goivf.com)

We are considering the use of CPT code 99211 for encounters during cycle management as part of ovulation induction. (asrm.org)
What is Ovulation and the things you need to know about your Ovulation Cycle? (fertilitycentrenepal.com)
I have a regular menstrual cycle and ovulation. (sharedjourney.com)
I rarely have to cancel an ovulation induction cycle using FSH. (sharedjourney.com)

Terms of ovulation induction and pregnancy rate. (bowencentersa.org)

In the simplest terms, letrozole induces ovulation. (bowencentersa.org)
The Lupron trigger induces the release of LH and FSH from the pituitary which then effectively induces oocyte maturation for either retrieval or ovulation induction. (goivf.com)

Polycystic ovarian syndrome patients with normospermic partners undergoing ovulation induction with letrozole had a higher live birth rate. (bowencentersa.org)
After surgery, ovulation was documented in 16 out of 18 (88.9%) patients. (who.int)
The risk of developing gynaecological cancer following ovulation induction therapy in infertile patients is not easy to determine due to many confounding factors. (fvvo.eu)
These findings provide new insight into the uterine epithelial changes and angiogenesis at the 3D level, and explain a potential reason for endometrial changes due to the low implantation rate in patients undergoing clinic super-ovulation. (frontiersin.org)
Patients who did not respond to ovulation induction d. (who.int)

Anatomy12

Organisms5

Diseases5

Chemicals and Drugs28

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes37

Information Science3

Health Care6

Differential transcriptional activity associated with chromatin configuration in fully grown mouse germinal vesicle oocytes. (1/1572)

Ovarian follicular responses in dairy cows treated with GnRH and cloprostenol. (2/1572)

Effect of exogenous gonadotropins on gonadotrophs of the rat pituitary gland. (3/1572)

Is there a difference in the function of granulosa-luteal cells in patients undergoing in-vitro fertilization either with gonadotrophin-releasing hormone agonist or gonadotrophin-releasing hormone antagonist? (4/1572)

Pharmaco-economic aspects of in-vitro fertilization in Italy. (5/1572)

Poor responders to ovulation induction: is proceeding to in-vitro fertilization worthwhile? (6/1572)

A prospective, randomized, double-blind clinical trial to study the efficacy and efficiency of a fixed dose of recombinant follicle stimulating hormone (Puregon) in women undergoing ovarian stimulation. (7/1572)

Sperm treatment with extracellular ATP increases fertilization rates in in-vitro fertilization for male factor infertility. (8/1572)

Ovulation Induction

Clomiphene

Anovulation

Fertility Agents, Female

Infertility, Female

Menotropins

Polycystic Ovary Syndrome

Gonadotropins

Ovarian Hyperstimulation Syndrome

Follicle Stimulating Hormone, Human

Pregnancy Rate

Follicle Stimulating Hormone

Ovary

Insemination, Artificial

Pregnancy

Chorionic Gonadotropin

Fertilization in Vitro

Live Birth

Ovarian Follicle

Insemination, Artificial, Homologous

Reproductive Techniques

Electrocoagulation

Pregnancy, Multiple

Nafarelin

Superovulation

Reproductive Techniques, Assisted

Infertility

Luteinizing Hormone

Metformin

Progesterone

Urofollitropin

Gonadotropin-Releasing Hormone

Pregnancy Outcome

Estradiol

Ovulation

Diathermy

Buserelin

Gonadotropins, Equine

Enzyme Induction

Embryo Transfer

Menstrual Cycle

Luteal Phase

Estrus

Fertility

Oocyte Retrieval

Follicular Fluid

Birth Rate

Oocytes

Leuprolide

Ovulation Inhibition

Endometrium

Sperm Injections, Intracytoplasmic

Menstruation

Uterus

Recombinant Proteins

Corpus Luteum

Litter Size

Embryo Implantation

Time Factors

Aromatase Inhibitors

Drug Resistance

Estrus Synchronization

Follicular Phase

Laparoscopy

Cryopreservation

Treatment Outcome

Prospective Studies

Retrospective Studies

Sheep

Estrus Detection

Granulosa Cells

Sexual Maturation

RNA, Messenger

Anestrus

Breeding

Estrous Cycle

Pregnanediol

Randomized Controlled Trials as Topic

Dinoprost

Proestrus