The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.
A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
CELL LINE derived from the ovary of the Chinese hamster, Cricetulus griseus (CRICETULUS). The species is a favorite for cytogenetic studies because of its small chromosome number. The cell line has provided model systems for the study of genetic alterations in cultured mammalian cells.
An OOCYTE-containing structure in the cortex of the OVARY. The oocyte is enclosed by a layer of GRANULOSA CELLS providing a nourishing microenvironment (FOLLICULAR FLUID). The number and size of follicles vary depending on the age and reproductive state of the female. The growing follicles are divided into five stages: primary, secondary, tertiary, Graafian, and atretic. Follicular growth and steroidogenesis depend on the presence of GONADOTROPINS.
A genus of the family Muridae consisting of eleven species. C. migratorius, the grey or Armenian hamster, and C. griseus, the Chinese hamster, are the two species used in biomedical research.
The discharge of an OVUM from a rupturing follicle in the OVARY.
Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).
A condition caused by the excessive secretion of ANDROGENS from the ADRENAL CORTEX; the OVARIES; or the TESTES. The clinical significance in males is negligible. In women, the common manifestations are HIRSUTISM and VIRILISM as seen in patients with POLYCYSTIC OVARY SYNDROME and ADRENOCORTICAL HYPERFUNCTION.
Pathological processes of the OVARY.
The degeneration and resorption of an OVARIAN FOLLICLE before it reaches maturity and ruptures.
The process of germ cell development in the female from the primordial germ cells through OOGONIA to the mature haploid ova (OVUM).
The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Follicle-stimulating hormone stimulates GAMETOGENESIS and the supporting cells such as the ovarian GRANULOSA CELLS, the testicular SERTOLI CELLS, and LEYDIG CELLS. FSH consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity.
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
Female germ cells derived from OOGONIA and termed OOCYTES when they enter MEIOSIS. The primary oocytes begin meiosis but are arrested at the diplotene state until OVULATION at PUBERTY to give rise to haploid secondary oocytes or ova (OVUM).
Gonadotropins secreted by the pituitary or the placenta in horses. This term generally refers to the gonadotropins found in the pregnant mare serum, a rich source of equine CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; and FOLLICLE STIMULATING HORMONE. Unlike that in humans, the equine LUTEINIZING HORMONE, BETA SUBUNIT is identical to the equine choronic gonadotropin, beta. Equine gonadotropins prepared from pregnant mare serum are used in reproductive studies.
The yellow body derived from the ruptured OVARIAN FOLLICLE after OVULATION. The process of corpus luteum formation, LUTEINIZATION, is regulated by LUTEINIZING HORMONE.
General term for CYSTS and cystic diseases of the OVARY.
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
A major gonadotropin secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Luteinizing hormone regulates steroid production by the interstitial cells of the TESTIS and the OVARY. The preovulatory LUTEINIZING HORMONE surge in females induces OVULATION, and subsequent LUTEINIZATION of the follicle. LUTEINIZING HORMONE consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the three pituitary glycoprotein hormones (TSH, LH and FSH), but the beta subunit is unique and confers its biological specificity.
The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Hormones that stimulate gonadal functions such as GAMETOGENESIS and sex steroid hormone production in the OVARY and the TESTIS. Major gonadotropins are glycoproteins produced primarily by the adenohypophysis (GONADOTROPINS, PITUITARY) and the placenta (CHORIONIC GONADOTROPIN). In some species, pituitary PROLACTIN and PLACENTAL LACTOGEN exert some luteotropic activities.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Suspension or cessation of OVULATION in animals or humans with follicle-containing ovaries (OVARIAN FOLLICLE). Depending on the etiology, OVULATION may be induced with appropriate therapy.
The period of cyclic physiological and behavior changes in non-primate female mammals that exhibit ESTRUS. The estrous cycle generally consists of 4 or 5 distinct periods corresponding to the endocrine status (PROESTRUS; ESTRUS; METESTRUS; DIESTRUS; and ANESTRUS).
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
The period in the ESTROUS CYCLE associated with maximum sexual receptivity and fertility in non-primate female mammals.
Abnormally infrequent menstruation.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Achievement of full sexual capacity in animals and in humans.
The male gonad containing two functional parts: the SEMINIFEROUS TUBULES for the production and transport of male germ cells (SPERMATOGENESIS) and the interstitial compartment containing LEYDIG CELLS that produce ANDROGENS.
Diminished or absent ability of a female to achieve conception.
A potent androgenic steroid and major product secreted by the LEYDIG CELLS of the TESTIS. Its production is stimulated by LUTEINIZING HORMONE from the PITUITARY GLAND. In turn, testosterone exerts feedback control of the pituitary LH and FSH secretion. Depending on the tissues, testosterone can be further converted to DIHYDROTESTOSTERONE or ESTRADIOL.
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The period of the MENSTRUAL CYCLE representing follicular growth, increase in ovarian estrogen (ESTROGENS) production, and epithelial proliferation of the ENDOMETRIUM. Follicular phase begins with the onset of MENSTRUATION and ends with OVULATION.
A glycoprotein that causes regression of MULLERIAN DUCTS. It is produced by SERTOLI CELLS of the TESTES. In the absence of this hormone, the Mullerian ducts develop into structures of the female reproductive tract. In males, defects of this hormone result in persistent Mullerian duct, a form of MALE PSEUDOHERMAPHRODITISM.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
The fluid surrounding the OVUM and GRANULOSA CELLS in the Graafian follicle (OVARIAN FOLLICLE). The follicular fluid contains sex steroids, glycoprotein hormones, plasma proteins, mucopolysaccharides, and enzymes.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Euploid female germ cells of an early stage of OOGENESIS, derived from primordial germ cells during ovarian differentiation. Oogonia undergo MEIOSIS and give rise to haploid OOCYTES
Established cell cultures that have the potential to propagate indefinitely.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.
The capacity to conceive or to induce conception. It may refer to either the male or female.
Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.
The total process by which organisms produce offspring. (Stedman, 25th ed)
Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.
A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system.
The surgical removal of one or both ovaries.
Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
Proteins prepared by recombinant DNA technology.
Glycoproteins that inhibit pituitary FOLLICLE STIMULATING HORMONE secretion. Inhibins are secreted by the Sertoli cells of the testes, the granulosa cells of the ovarian follicles, the placenta, and other tissues. Inhibins and ACTIVINS are modulators of FOLLICLE STIMULATING HORMONE secretions; both groups belong to the TGF-beta superfamily, as the TRANSFORMING GROWTH FACTOR BETA. Inhibins consist of a disulfide-linked heterodimer with a unique alpha linked to either a beta A or a beta B subunit to form inhibin A or inhibin B, respectively
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
The active production and accumulation of VITELLINS (egg yolk proteins) in the non-mammalian OOCYTES from circulating precursors, VITELLOGENINS. Vitellogenesis usually begins after the first MEIOSIS and is regulated by estrogenic hormones.
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.
The gamete-producing glands, OVARY or TESTIS.
The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
A mature haploid female germ cell extruded from the OVARY at OVULATION.
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
Hormones produced in the testis.
Compounds which increase the capacity to conceive in females.
Six-carbon alicyclic hydrocarbons which contain one or more double bonds in the ring. The cyclohexadienes are not aromatic, in contrast to BENZOQUINONES which are sometimes called 2,5-cyclohexadiene-1,4-diones.
PROGESTERONE-producing cells in the CORPUS LUTEUM. The large luteal cells derive from the GRANULOSA CELLS. The small luteal cells derive from the THECA CELLS.
The reproductive cells in multicellular organisms at various stages during GAMETOGENESIS.
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.
An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.

Effect of sex difference on the in vitro and in vivo metabolism of aflatoxin B1 by the rat. (1/8699)

Hepatic microsome-catalyzed metabolism of aflatoxin B1 (AFB1) to aflatoxin M1 and aflatoxin Q1 and the "metabolic activation" of AFB1 to DNA-alylating metabolite(s) were studied in normal male and female Sprague-Dawley rats, in gonadectomized animals, and in castrated males and normal females treated with testosterone. Microsomes from male animals formed 2 to 5 times more aflatoxin M1, aflatoxin Q1, and DNA-alkylating metabolite(s) than those from females. Castration reduced the metabolism of AFB1 by the microsomes from males by about 50%, whereas ovariectomy had no significant effect on AFB1 metabolism by the microsomes from females. Testosterone treatment (4 mg/rat, 3 times/week for about 6 weeks) of castrated immature males and immature females enhanced the metabolism of AFB1 by their microsomes. A sex difference in the metabolism of AFB1 by liver microsomes was also seen in other strains of rats tested: Wistar, Long-Evans, and Fischer. The activity of kidney microsomes for metabolic activation was 1 to 4% that of the liver activity and was generally lower in microsomes from male rats as compared to those from female rats of Sprague-Dawley, Wistar, and Long-Evans strains. The in vitro results obtained with hepatic microsomes correlated well with the in vivo metabolism of AFB1, in that more AFB1 became bound in vivo to hepatic DNA isolated from male rats and from a female rat treated with testosterone than that isolated from control female rats. These data suggest that the differences in hepatic AFB1 metabolism may be the underlying cause of the sex difference in toxicity and carcinogenicity of AFB1 observed in rats.  (+info)

Apontic binds the translational repressor Bruno and is implicated in regulation of oskar mRNA translation. (2/8699)

The product of the oskar gene directs posterior patterning in the Drosophila oocyte, where it must be deployed specifically at the posterior pole. Proper expression relies on the coordinated localization and translational control of the oskar mRNA. Translational repression prior to localization of the transcript is mediated, in part, by the Bruno protein, which binds to discrete sites in the 3' untranslated region of the oskar mRNA. To begin to understand how Bruno acts in translational repression, we performed a yeast two-hybrid screen to identify Bruno-interacting proteins. One interactor, described here, is the product of the apontic gene. Coimmunoprecipitation experiments lend biochemical support to the idea that Bruno and Apontic proteins physically interact in Drosophila. Genetic experiments using mutants defective in apontic and bruno reveal a functional interaction between these genes. Given this interaction, Apontic is likely to act together with Bruno in translational repression of oskar mRNA. Interestingly, Apontic, like Bruno, is an RNA-binding protein and specifically binds certain regions of the oskar mRNA 3' untranslated region.  (+info)

Utero-ovarian interaction in the regulation of reproductive function. (3/8699)

The physiological regulation of fertile reproductive cycle in mammals depends on interactions between hypothalamus-pituitary, ovarian and uterine stimuli. Over the past 20 years, much has been learned about the interrelation between the affluent and effluent lymph and vascular drainage in and around both ovarian and uterine tissues. An essential feature in the regulation of the fertile cycle is the functional status of the ovary, particularly the corpus luteum. During the time of implantation and the early pregnancy, an active corpus luteum is essential. As human chorionic gonadotrophin (HCG) is important in the maintenance of the corpus luteum, we investigated if it was produced by the cyclic endometrium. Immunohistochemical and in-situ hybridization reactions were performed but neither identified the presence of HCG during the proliferative phase. Positive staining and beta-human chorionic gonadotrophin (beta-HCG) mRNA were observed during the secretory phase in the glandular cells of the endometrium. The results were confirmed by Western blotting of secretory phase endometrium extracts and assessment of the functional secretory capacity of primary endometrial cultures. Polymerase chain reaction (PCR) investigations showed a positive result in the secretory phase. We postulate that, based on the very close morphological interrelation between the uterus and the ovary, the beta-HCG of the endometrium is the primary factor for the maintenance of the corpus luteum and early pregnancy.  (+info)

Uterine peristalsis during the follicular phase of the menstrual cycle: effects of oestrogen, antioestrogen and oxytocin. (4/8699)

Uterine peristalsis, directing sustained and rapid sperm transport from the external cervical os or the cervical crypts to the isthmic part of the tube ipsilateral to the dominant follicle, changes in direction and frequency during the menstrual cycle, with lowest activity during menstruation and highest activity at mid cycle. It was therefore suggested that uterine peristalsis is under the control of the dominant follicle with the additional involvement of oxytocin. To test this hypothesis, vaginal sonography of uterine peristalsis was performed in the early, mid and late proliferative phases, respectively, of cycles of women treated with oestradiol valerate and with human menopausal gonadotrophin following pituitary downregulation, with clomiphene citrate and with intravenous oxytocin, respectively. Administration of oestradiol valerate resulted in oestradiol serum concentrations comparable with the normal cycle with a simulation of the normal frequency of peristaltic contractions. Elevated oestradiol concentrations and bolus injections of oxytocin resulted in a significant increase in the frequency of peristaltic contractions in the early and mid follicular phases, respectively. Chlomiphene tended, though insignificantly so, to suppress the frequency of peristaltic waves in the presence of elevated oestradiol concentrations. In the late follicular phase of the cycle extremely elevated oestradiol concentrations as well as the injection of oxytocin resulted only in an insignificant further increase of peristaltic frequency. In the normal cycles, as well as during extremely elevated oestradiol concentrations and following oxytocin administration, the peristaltic contractions were always confined to the subendometrial layer of the muscular wall. The results and the review of literature indicate that uterine peristalsis during the follicular phase of the menstrual cycle is controlled by oestradiol released from the dominant follicle with the probable involvement of oxytocin, which is presumably stimulated together with its receptor within the endometrial-subendometrial unit and therefore acting in an autocrine/paracrine fashion. Since unphysiological stimulation with oestradiol and oxytocin did not significantly increase the frequency of uterine peristalsis in the late follicular phase of the cycle it is assumed that normal preovulatory frequency of uterine peristalsis is at a level which cannot be significantly surpassed due to phenomena of refractoriness of the system.  (+info)

Sonographic evidence for the involvement of the utero-ovarian counter-current system in the ovarian control of directed uterine sperm transport. (5/8699)

Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvasculare of the myometrium, which exhibits a predominantly circular arrangement of muscular fibres that separate at the fundal level into the fibres of the cornua and continue into the circular muscles of the respective tubes. Since spermatozoa are transported preferentially into the tube ipsilateral to the dominant follicle, this asymmetric uterine function may be controlled by the ovary via direct effects utilizing the utero-ovarian counter-current system, in addition to the systemic circulation. To test this possibility the sonographic characteristics of the uterine vascular bed were studied during different phases of the menstrual cycle. Vaginal sonography with the measurement of Doppler flow characteristics of both uterine arteries and of the arterial anastomoses of the uterine and ovarian arteries (junctional vessels) in the cornual region of both sides of the uterus during the menstrual phase of regular-cycling women demonstrated significant lower resistance indices of the junctional vessels ipsilateral to the side of the dominant ovarian structure as compared with the corresponding arteries contralaterally. By the use of the perfusion mode technique, it could be observed that vascular perfusion of the fundal myometrium was significantly increased ipsilateral to the dominant follicle during the late follicular phase of the cycle. These results show that the endocrine control of the dominant ovarian structure over uterine function is not only exerted via the systemic circulation but also directly, most probably utilizing the utero-ovarian counter-current system.  (+info)

Endometriotic disease: the role of peritoneal fluid. (6/8699)

Peritoneal fluid and the intraovarian milieu are a specific microenvironment. Peritoneal fluid originates mainly as an ovarian exudation product caused by increased vascular permeability, with cyclic variation in volume and steroid hormones which are always higher than in plasma. It contains large amounts of macrophages and their secretion products, and has a large exchange area with plasma through the peritoneum, which is highly permeable for small molecules. Diffusion becomes virtually zero for molecules with a molecular weight of >100000 Da. In women with the luteinized unruptured follicle (LUF) syndrome, concentrations of oestrogens and progesterone are much lower in the luteal phase. Endometriosis is associated with sterile low-grade inflammation, increased concentrations of activated macrophages and many of their secretions, such as cytokines, growth factors and angiogenic factors. Concentrations of CA-125 and of glycodelins are also increased, secreted locally by the endometrial cells. Natural killer (NK) cell function declines, possibly mediated by glycodelins or local intercellular adhesion molecule (ICAM) -1 shedding. The ovary is also a specific microenvironment, with steroid hormone concentrations 1000-fold higher in follicles than in plasma. Endometrial and superficially implanted cells are influenced by peritoneal fluid concentrations so that local environment, rather than inherent cellular differences could explain differences between superficial endometriosis and eutopic endometrium. Differences between superficial implants and endometriotic disease, deep infiltrating or cystic ovarian endometriosis, may thus arise via different endocrine environments. Superficial endometrial implants are regulated by peritoneal fluid factors, whereas deep endometriosis and cystic ovarian endometriosis are influenced by blood or ovarian factors. The endometriotic disease theory considers superficial endometriotic implants and their remodelling as a physiological process in most women, and concentrates on the causes of severe endometriosis such as differences in the eutopic endometrium from women with and without endometriosis (which may indicate hereditary differences), the invasiveness of some endometriotic cells in vitro, focal 'shielding' of endometriotic foci by adhesions, and inhibition of NK activity by ICAM-1 and glycodelins. Endometriotic disease is thus seen as a benign tumour. The type of cellular lesion, hereditary and immunological environments and local hormone concentrations in the ovary and in peritoneal fluid, will decide expression as cystic ovarian endometriosis, deep endometriosis or adenomyosis externa, and whether the latter is associated with adhesions.  (+info)

Leptin and reproduction. (7/8699)

In the few years since leptin was identified as a satiety factor in rodents, it has been implicated in the regulation of various physiological processes. Leptin has been shown to promote sexual maturation in rodent species and a role in reproduction has been investigated at various sites within the hypothalamo-pituitary-gonadal axis. This review considers the evidence that leptin (or alteration in amount of body fat) can affect reproduction. There is evidence that leptin plays a permissive role in the onset of puberty, probably through action on the hypothalamus, where leptin receptors are found in cells that express appetite-regulating peptides. There is little evidence that leptin has a positive effect on the pituitary gonadotrophs and the gonads. There is also very little indication that leptin acts in an acute manner to regulate reproduction in the short term. It seems more likely that leptin is a 'barometer' of body condition that sends signals to the brain. Studies in vitro have shown negative effects on ovarian steroid production and there are no reports of effects on testicular function. Leptin concentrations in plasma increase in women during pregnancy, owing to production by the placenta but the functional significance of this is unknown. A number of factors that affect the production and action of leptin have yet to be studied in detail.  (+info)

Effect of shellfish calcium on the apparent absorption of calcium and bone metabolism in ovariectomized rats. (8/8699)

Fossil shellfish powder (FS) and Ezo giant scallop shell powder (EG) were rendered soluble with lactate and citrate under decompression (FSEx and EGEx, respectively) and we examined the effects of lactate-citrate solubilization of FS and EG on mineral absorption, tissue mineral contents, serum biochemical indices and bone mineral density (BMD) in ovariectomized (OVX) rats. The apparent absorption ratios of minerals tended to be high in the rats fed with the solubilized mineral sources, those in the FSEx group being significantly higher than in the FS group. There was no significant difference in the tibia mineral content among the OVX groups. BMD at the distal femoral diaphysis was significantly increased by FSEx and EGEx feeding. It is suggested that solubilization with lactate and citrate under decompression increased the solubility and bioavailability of calcium from such natural sources of shellfish calcium as FS and EG.  (+info)

The adult ovarian surface epithelium has already been proposed as a source of stem cells and germinal cells in the literature, it has been termed the germinal epithelium therefore. that neonatal and adult mouse ovaries have come cells which can become effectively proliferated and verified [1C3]. Pacchiarotti et al. [2] discovered in neonatal and adult mouse ovaries two unique populations of feminine germline come cells with different diameters: cells with diameters of 10C15?transgene. These results lead to the fundamental study of ovarian come cells, oogenesis, and a fresh understanding of the physiology of the mammalian ovary and demonstrated that ovarian surface area epithelium might become an essential resource of germinal come cells in adult mouse ovaries. In addition to the mouse model, many related research in human beings also display that adult human being ovarian surface area epithelium might become a resource of Galeterone control cells. Bukovsky et al. verified that oocyte-like cells ...
TY - JOUR. T1 - Follicular development, ovulation, and corpus luteum formation in cryopreserved human ovarian tissue after xenotransplantation. AU - Kim, S. Samuel. AU - Soules, Michael R.. AU - Battaglia, David E.. PY - 2002/7/15. Y1 - 2002/7/15. N2 - Objective: To assess the competency of human frozen/thawed ovarian follicles matured in xenografts to form functioning corpora luteae after human chorionic gonadotropin (hCG) administration. Design: Prospective controlled animal study. Setting: University research laboratory. Patient(s): Three women (19, 28, and 36 years) who underwent oophorectomy. Animal(s): Nineteen female severe combined immunodeficient (SCID) mice. Intervention(s): Cryopreserved human ovarian tissues were grafted into the s.c. space of bilaterally oophorectomized SCID mice. All the animals were stimulated with pregnant mares serum gonadotropin (PMSG) for 4 weeks starting from 16 weeks after transplantation. Twelve animals were injected with hCG at the end of gonadotropin ...
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The adult ovarian surface epithelium has already been proposed as a source of stem cells and germinal cells in the literature, it has been termed the germinal epithelium therefore. that neonatal and adult mouse ovaries have come cells which can become effectively proliferated and verified [1C3]. Pacchiarotti et al. [2] discovered in neonatal and adult mouse ovaries two unique populations of feminine germline come cells with different diameters: cells with diameters of 10C15?transgene. These results lead to the fundamental study of ovarian come cells, oogenesis, and a fresh understanding of the physiology of the mammalian ovary and demonstrated that ovarian surface area epithelium might become an essential resource of germinal come cells in adult mouse ovaries. In addition to the mouse model, many related research in human beings also display that adult human being ovarian surface area epithelium might become a resource of Galeterone control cells. Bukovsky et al. verified that oocyte-like cells ...
Answer (1 of 1): The ovaries are part of the female reproductive system, and are found in pairs among vertebrates (animals with spines). If youre a girl, youll have ovaries in your lower stomach area, where your pelvis is.Where Are The Ovaries, And What Do They Do? In human females, the ovaries are located in the pelvic area, either side of the uterus. Each one is about the size of an almond, and they release a single egg every month, unless youre pregnant.If you have sex, your partners sperm can fertilize this egg, which then turns into a baby. If the egg isnt used, you flush it out during your period, and your ovaries will release another one the following month.How Can I Feel Where My Ovaries Are? The ovaries can be found about four inches below the navel. Each one is out three inches to the side, so that should be just above and inside your hipbones if youre of average height!Youll need to know where your ovaries are if you want to perform a fertility massage. This is supposed to increase
This study demonstrates that different PKC isoforms are differentially expressed in particular cellular components of ovarian follicles of pre-pubertal, pubertal and adult mouse ovaries.. Data obtained from H-Score evaluation of immunohistochemistry findings revealed that PKCα expression was more apparent in oocytes of all follicles in pre-pubertal, pubertal and adult ovaries, though it was also expressed in granulosa cells. Interestingly, in adult and pre-pubertal ovaries, intense immunostaining of PKCα in oocytes was statistically significant in primordial (PND60, PND7 and PND1), primary (PND60, PND7 and PND1) and secondary follicles (PND60 and PND7), whereas in PND21 ovaries only oocytes of primordial follicles had significantly higher immunostaining level of PKCα. These findings support the idea that PKCα expression in oocytes of larger follicles may have low significance due to granulosa-oocyte interactions during initiation of hormone dependent follicular growth [27],[28]. PKCα ...
Diminished ovarian reserve is associated with a poor ovarian response (POR) to gonadotropin stimulation and IVF outcomes. Whether pretreatment with DHEA improves the ovarian response in DOR patients remains debated. In the present study, no statistically significant improvement in ovarian reserve markers, ovarian response, or IVF outcomes was found. However, subgroup analysis showed that the expression of AR and FSHR mRNA in GCs were significantly increased in women with ≥5 oocytes retrieved after DHEA pretreatment, suggesting that DHEA may improve the ovarian response in DOR women through promoting the expression of AR and FSHR in GCs.. Although many studies have focused on the effects of androgens and AR on follicular development, the conclusions are controversial. A recent meta-analysis indicated the clinical pregnancy rate was statistically increased in DOR patients who were pre-treated with DHEA, there was no significant improvement on the number of oocytes retrieved and the cancellation ...
The Drosophila ovary consists of repeated units, the ovarioles, where oogenesis takes place. The repetitive structure of the ovary develops de novo from a mesenchymal cell mass, a process that is initiated by the formation of a two-dimensional array of cell stacks, called terminal filaments, during the third larval instar. We have studied the morphogenetic process leading to the formation of terminal filaments and find that this involves recruitment, intercalation and sorting of terminal filament cells. Two other types of cell stacks that participate in ovary morphogenesis, the basal stalks and interfollicular stalks, also form by cell rearrangement utilizing a convergence and extension mechanism. Terminal filament formation depends on the Bric a brac protein, which is expressed in the nuclei of terminal filament cells and is cell autonomously required. Disruption of terminal filament formation, together with defects of basal and interfollicular stalk development, leads to disruption of ovariole ...
Light microscopy of the fetal primate ovary about 20 weeks of gestation. The ovary is densely populated with oocytes (female germ cells) enclosed with a layer of follicle cells which together are known as follicles. The earliest follicles are called primordial follicles. In most species the fetal ovary is massively oversupplied with oocytes/follicles; in humans there may be up to 5 million per ovary. For reasons that remain unknown the majority (approximately 85%) of follicles die with a few hundred thousand surviving in each ovary at birth. Magnification x180 when narrow width printed at 10 cm. - Stock Image C024/0084
Talk Page}} ==2020== Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary Wanbao Niu and Allan C. Spradling PNAS August 18, 2020 117 (33) 20015-20026; first published August 5, 2020 Significance This paper improves knowledge of the somatic and germ cells of the developing mouse ovary that assemble into ovarian follicles, by determining cellular gene expression, and tracing lineage relationships. The study covers the last week of fetal development through the first five days of postnatal development. During this time, many critically important processes take place, including sex determination, follicle assembly, and the initial events of meiosis. We report expression differences between pregranulosa cells of wave 1 follicles that function at puberty and wave 2 follicles that sustain fertility. These studies illuminate ovarian somatic cells and provide ...
Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary Wanbao Niu and Allan C. Spradling PNAS August 18, 2020 117 (33) 20015-20026; first published August 5, 2020 Significance This paper improves knowledge of the somatic and germ cells of the developing mouse ovary that assemble into ovarian follicles, by determining cellular gene expression, and tracing lineage relationships. The study covers the last week of fetal development through the first five days of postnatal development. During this time, many critically important processes take place, including sex determination, follicle assembly, and the initial events of meiosis. We report expression differences between pregranulosa cells of wave 1 follicles that function at puberty and wave 2 follicles that sustain fertility. These studies illuminate ovarian somatic cells and provide a resource to study ...
Jacobs, B B., In vivo assay of function of mouse ovaries following culture in hormone enriched medium. (1963). Subject Strain Bibliography 1963. 546 ...
Some strains, despite all our efforts they just dont breed well. Fortunately, techniques such as ovarian transplantation are available to overcome such problems and improve the breeding performance of troublesome colonies.
A reliable indirect measure of ovarian reserve for the individual woman remains a challenge for reproductive specialists. Using descriptive statistics from a large-scale study of ovarian volumes, we have developed a normative model for healthy females for ages 25 through 85. For average values, this model has a strong and positive correlation (r=0.89) with our recent model of nongrowing follicles (NGFs) in the human ovary for ages 25 through 51. When both models are log-adjusted, the correlation increases to r=0.99, over the full range of ovarian volume. Furthermore we can deduce that an ovary of 3 cm3 volume (or less) contains approximately 1000 NGF (or fewer). These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman ...
View more ,Fibrillins 1-3 are stromal extracellular matrix proteins that play important roles in regulating TGFβ activity, which stimulates fibroblasts to proliferate and synthesize collagen. In the developing ovary, the action of stroma is initially necessary for the formation of ovigerous cords and subsequently for the formation of follicles and the surface epithelium of the ovary. FBN3 is highly expressed only in early ovarian development and then it declines. In contrast, FBN1 and 2 are upregulated in later ovarian development. We examined the expression of FBN1-3 in bovine and human fetal ovaries. We used cell dispersion and monolayer culture, cell passaging and tissue culture. Cells were treated with growth factors, hormones or inhibitors to assess the regulation of expression of FBN1-3. When bovine fetal ovarian tissue was cultured, FBN3 expression declined significantly. Treatment with TGFβ-1 increased FBN1 and FBN2 expression in bovine fibroblasts, but did not affect FBN3 expression. ...
Although ovarian cancer is rare, it is the most deadly of gynaecological cancers. Unfortunately, still very little is known about the cells that give rise to 90% of ovarian cancers, the ovarian surface epithelial (OSE) cells, and much of the available data remains controversial. This project was designed to address the possible involvement of ovarian stromal/thecal cells in the regulation of OSE cell growth and Kit and KL expression. Such interactions are probably involved in normal OSE-stromal/thecal cell activities as well as in interactions occurring within inclusion cysts and leading to ovarian tumour formation. The regulation of rat OSE (ROSE) cell growth by theca-derived factors and gonadotropins was investigated by proliferation experiments and cell counts. The modulation of Kit and Kit ligand (KL) messenger ribonucleic acid (mRNA) expression in these cells by the same factors was investigated by Northern blot analysis and reverse transcription-polymerase chain reaction (RT-PCR). ...
In female mammals, proper oocyte development is a vital prerequisite for future gamete viability and fertility. This development of oocytes, known as oogenesis, begins with the migration of primordial germ cells to the genital ridge of the early embryo, where multiple rounds of mitotic division occur without complete cytokinesis. The result is temporary cyst morphology. Cyst breakdown is a crucial process in the next developmental stage, resulting in formation of the single oocytes which will grow in follicles surrounded by granulosa cells and eventually develop into eggs. These aspects of embryogenesis are conserved across multiple species, including Drosophila, mice, and humans. Extensive research has already been completed to elucidate the mechanisms through which the steroid hormone estrogen regulates these developmental processes. Some research shows that progesterone, among other steroid hormones, also plays a role in inhibiting cyst breakdown and disrupting proper follicular assembly. However,
In the flowering plants, an ovary is a part of the female reproductive organ of the flower or gynoecium. Specifically, it is the part of the carpel which holds the ovule(s) and is located above or below or at the point of connection with the base of the petals and sepals. In this picture of a zucchini the petals and sepals are above the ovary and such a flower is said to have an inferior ovary; also referred to as epigynous. Above the ovary is the style and the stigma, which is where the pollen lands and germinates to grow down through the style to the ovary, and, for each individual pollen grain, to grow into one individual ovule. Some wind pollinated flowers have much reduced and modified ovaries. The carpel together with all the female components including ovules, placental tissue, style and stigma are called gynoecium. The carpel is considered to be a modified leaf. A pea shell is a good example of a carpel and shows the genetic and morphological relationship to a leaf.. ...
The only difference between a woman with one ovary and a woman with both ovaries is that the woman with one ovary may go through menopause sooner. According to Dr. Peter Kenemans at, Early removal of one ovary or a substantial part of a functional ovary (e.g., by a large wedge resection) can provoke menopause by reducing the actual amount of follicles still present. You still still experience the same symptoms, but there is no other dramatic change. ...
Ovarian vein thrombosis after a cesarean section with a thrombus filled right ovarian vein extending into the inferior vena cava ...
The prolonged, gonadotoxic effect of chemotherapy can finally lead to infertility in female cancer survivors. There is controversial evidence regarding the protective role of gonadotropin-releasing hormone analogue (GnRH-a) on chemotherapy-induced ovarian damage. In the present study on a murine model, ultrasound (US) and contrast-enhanced US (CEUS) were firstly used to characterise ovarian glands in normal conditions to validate a preclinical model. In addition, preliminary findings were obtained on anatomical and vascular ovarian changes induced by GnRH-a based on decapeptyl administration. Ovaries were accurately assessed with US and CEUS in a murine model placed in prone position, providing quantitative and reproducible information. Ovaries were identified in 40/40 cases and CEUS analysis was successfully performed in 20/20 cases with 100% technical success. A statistically significant increase of the diameter of the dominant follicle at US and a statistically significant reduced vascularisation at
Women may not have a finite number of eggs.Researchers have isolated stem cells from adult human ovaries that could produce eggs.
Management of women with reduced ovarian reserve or poor ovarian response (POR) to stimulation is one of the major challenges in reproductive medicine. The primary causes of POR remain elusive and oxidative stress was proposed as one of the important contributors. It has been suggested that focus on the specific subpopulations within heterogeneous group of poor responders could assist in evaluating optimal management strategies for these patients. This study investigated the effect of anti-oxidant treatment with coenzyme Q10 (CoQ10) on ovarian response and embryo quality in young low-prognosis patients with POR. This prospective, randomized controlled study included 186 consecutive patients with POR stratified according to the POSEIDON classification group 3 (age | 35, poor ovarian reserve parameters). The participants were randomized to the CoQ10 pre-treatment for 60 days preceding IVF-ICSI cycle or no pre-treatment. The number of high quality embryos was a primary outcome measure. A total of 169
Management of women with reduced ovarian reserve or poor ovarian response (POR) to stimulation is one of the major challenges in reproductive medicine. The primary causes of POR remain elusive and oxidative stress was proposed as one of the important contributors. It has been suggested that focus on the specific subpopulations within heterogeneous group of poor responders could assist in evaluating optimal management strategies for these patients. This study investigated the effect of anti-oxidant treatment with coenzyme Q10 (CoQ10) on ovarian response and embryo quality in young low-prognosis patients with POR. This prospective, randomized controlled study included 186 consecutive patients with POR stratified according to the POSEIDON classification group 3 (age | 35, poor ovarian reserve parameters). The participants were randomized to the CoQ10 pre-treatment for 60 days preceding IVF-ICSI cycle or no pre-treatment. The number of high quality embryos was a primary outcome measure. A total of 169
High-fat diet (HFD) consumption in female rodents causes impaired estrous cyclicity, fewer pups per litter, and dysregulation of key ovulatory genes suggesting that HFD-induced subfertility may be due to ovulatory dysfunction. To test this hypothesis female mice were fed chow or HFD for 10 weeks at which point ovulation and ovarian gene expression of endothelin-2 (Edn2), a gene critical for ovulation, were assessed. After 10 weeks of HFD, both mice that remained lean and those that became obese had fewer ovulated oocytes than chow controls (P = 0.041, P = 0.0030, respectively). In chow controls, Edn2 was expressed as expected with basal levels during diestrus and proestrus, increased 11.6-fold during estrus, and decreased to basal levels during metestrus. In HFD mice, Edn2 was dysregulated across the entire estrous cycle as were other Edn2 system components (endothelin converting enzyme 1 (Ece-1), and the endothelin receptors (Ednra, Ednrb)). Interestingly, we found dysregulation of key ovarian ...
Purified Human Ovary Cytoplasmic Tumor Lysate from Creative Biomart. Human Ovary Cytoplasmic Tumor Lysate can be used for research.
Both castes of Scaptotrigolia postica (Latreille, 1804) possess four ovarioles in each ovary. Queen and workers have the same ovarian development during the larvallife, but in lhe late larval stage the queen ovary beco me larger. During pupation a higher rate of cell division is observed in queen ovarioles and a higher rale of cell death in workers. Newly emerged workers have short ovarioles with differenriatcd germarium and vitellarium while queens have very long ovarioles with only germarium. Caste deterrnination in rhis species of bee is trophic, but lhe food does not differ in quality, only in quantiry. The food differences only beco me effecri ve by the end of larval stage when the queen larvae have lhe opportunity of eat more. In this way lhe ovary ...
Have you been diagnosed with a cyst on ovary? This may seem like a terrifying diagnosis, but it happens to many women.What Are Ovaries? The ovaries are two
Biology Assignment Help, Functions of ovary, Functions of Ovary The ovary of vertebrates performs the following functions: Production of eggs, Synthesis of hormones needed for the chemical coordination of reproduction, Elaboration of nutrient material (yolk) for the early sta
The expression of HeLa cell miR-15 to miR-33 was examined by Northern blotting using HeLa cell total RNA, in addition to total RNA prepared from mouse kidney, adult zebrafish, Xenopus laevis ovary, and D. melanogaster S2 cells (Fig. 1B andTable 2). miR-15 and miR-16 are encoded in a gene cluster (Fig. 2B) and are detected in mouse kidney, adult zebrafish, and very weakly in frog ovary, which may result from miRNA expression in somatic ovary tissue rather than in oocytes. mir-17 to mir-20 are also clustered (Fig. 2B) and are expressed in HeLa cells and adult zebrafish, but undetectable in mouse kidney and frog ovary (Fig. 1 andTable 2), and therefore represent a likely case of tissue-specific miRNA expression.. The majority of vertebrate and invertebrate miRNAs identified in this study are not related by sequence, but a few exceptions do exist and are similar to results previously reported for let-7 RNA (8). Sequence analysis of the D. melanogaster miRNAs revealed four such instances of sequence ...
In this review we analyze the involvement of cytokines in regulation of ovarian function. A growing body of evidence suggests that the ovary is a site of inflammatory reactions. Immune-competent cells present within the ovary may constitute potential in-situ modulators of ovarian function that act through local secretion of regulatory soluble factors - cytokines. In addition many over cell in the ovary also pro- duce cytokines independently of the presence of leukocytes, thus ovaries are sites of cytokine action and production. There are many evidences that cytokines are involved in the ovarian control of follicular development and are surveyed as the important regulators of steroidogenesis and gamete produc- tion. It is established that cytokines generally inhibit gonadot- ropin-stimulated production of steroids. However ovarian ste- roids, in turn, reduce the cytokine production by immune- competent cells. There are some data about participation of cytokines in regulating the proliferation and ...
Incredibly, each young female infant is born with all of her potential eggs. In fact, most girls are born with an estimated 1,000,000 eggs. A womans eggs cannot be created, copied, or grown; moreover, eggs are simply an inherent part of even a nearly fully developed fetus female anatomy. The Ovaries, which store these eggs, must mature one egg each month (for women with a regular menstrual / reproductive cycle), as the Ovaries must also send the matured egg off to the Fallopian Tubes. As there is both a right and left Ovary, each Ovary takes turns, as one will release an egg one month, while the other takes over for the next month ...
What are the chances that a mass is cancerous if it is vascular, attached to the right ovary, and the size of a grapefruit? They removed the mass and left the ovary intact.
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What makes the artificial ovary a functional tissue, rather than just a cell culture, is that it brings all three ovarian cell types into a 3-D arrangement similar to a real ovary in the body. The means for making such compositions of cells was invented in the lab of Jeffrey Morgan, associate professor of medical science and engineering, who is a co-author of the paper published online Aug. 25. His so-called 3D Petri dishes are made of a moldable agarose gel that provides a nurturing template to encourage cells to assemble into specific shapes. ...
《 selfology® OVARY CARE 自我生態®子宮卵巢保養 》 Part of the selfology® One Vitality Programs 自我生態® 一活力法 Selfologys multi-faceted Ovary care program is designed to boost ones overall vitality through the focus on ovaries care. A combination of thoughtful methodologies that includes hormonal balancing, vitality/fertility acupre
Can women get pregnant with only one ovary? Yes. When a woman has two ovaries, they usually take turns releasing the egg every month. If theres just one ovary, it will take over producing estrogen and releasing an egg every month, as long as the remaining ovary and fallopian tube are healthy. If … [Read more...] ...
An experimental technique may help preserve fertility in cancer patients and other women struck with premature infertility. It may even be used for healthy women who just want to wait
For the first time after a womans fertility was restored from an ovarian tissue transplant, she has given birth to two girls. The first with the help of fertility treatment, but the second, a surprise pregnancy, was a natural and unassisted conception. The mother, Mrs.
Whether you have a sharp pain in your ovary or experience dull aching ovaries, any pain in the area can be uncomfortable and a cause for concern. There are a number of causes of ovary pain and a variety of reasons for ovary pain.
Question - Left ovary removed, irregular periods, no periods this month, not pregnant. Normal symptoms?. Ask a Doctor about Ovary removal, Ask an OBGYN, Gynecologic Oncology
I only ever get pain from my left ovary.. It got me wondering if there was something wrong with my right one so I Googled (as you do!!) and came across quite a few posts from other forums saying that this can be quite normal and doesnt mean there is anything wrong.. The long and short of what I read was that one ovary can go about its business nice and quietly while the other might make a huge song and dance about it. My left one is obviously just an attention seeker!!!!. Anyone else only ever feel pain on one side when ovulating? ...
Hello and thanks for reading. I am currently almost 9 weeks pregnant and during a transvaginal ultrasound a solid 2.2 cm mass was seen on my ovary. Now of course im freaking out and have already diagn...
A team of Belgian doctors have managed to restore fertility in a 27-year-old woman using a piece of ovarian tissue that was removed and frozen when she was 13. This is the first time this procedure has worked with non-adult tissue, offering new hope for women who are infertile as a result of medical treatments during their childhood. The case study has been published in the journal Human Reproduction.. This is an important breakthrough in the field because children are the patients who are most likely to benefit from the procedure in the future, said lead author, researcher and gynaecologist Isabelle Demeestere, in a press release. When they are diagnosed with diseases that require treatment that can destroy ovarian function, freezing ovarian tissue is the only available option for preserving their fertility.. At the age of 13, the patient described in the new study underwent chemotherapy so that she could receive a bone marrow transplant from her brother, intended to treat severe ...
The female gonads are called the ovaries. In this article, we will initially look at the basic function, location, components and clinical significance of the ovaries. The latter part of the article will cover the ligaments associated with the ovaries and their vasculature, lymphatic drainage and innervation.
0U90XZZ is a billable procedure code used to indicate the performance of drainage of right ovary, external approach. Code valid for the year 2021
I have been thinking about what to do. Since lufs is my main problem. I would like to ignore the number and focus on using my good ovary and see how the Lupron and G-csf affect my LUFS. Statistically the right ovary goes more often than the left so this may be tricky. I may have to go back on stims to work them both. If nothing makes me rupture then I am done for good. Then if I do rupture but do not have success then I would consider having another surgery and get my ovary cleaned up. I have already had 5 and I really do not want to have another. I honestly do not know if my DH could take another one with the expense, travel, time off, emotions etc ...
Before this technology can be used in human preservation the perfusion rates and the levels of anti-coagulant will need to be optimised for different sized ovaries and of course trials on the normality of offspring will be required. Additionally it could also perhaps be applied to the cryo-preservation of other organs and even one day major ones such as kidneys where there are considerable difficulties in storing donated tissue. Although an organ, the ovary is small - though still with multiple cell types and a separate blood supply. So far attempts to freeze and store larger whole organs such as the heart, liver and kidney have proved unsuccessful. The primary challenge with whole organ cryo-preservation is that of preserving an intact vascular system and the Nottingham work, funded by the UKs Medical Research Council - is a major step in the right direction ...
OUTLINE: This is a pilot, prospective study.. Patients undergo a transvaginal or transabdominal ultrasound to measure the ovarian volume and count the number of antral follicles at baseline, 3 months after beginning cytotoxic chemotherapy, and at 6 months after completion of treatment. Patients undergo blood collection at the same time points for follicle-stimulating hormone, estradiol, and inhibin B levels. Patients are also asked to fill out questionnaires on estrogen-depletion symptoms at those times. Patients also keep a calendar of menstrual bleeding and hormonal medications.. PROJECTED ACCRUAL: A total of 22 patients will be accrued for this study. ...
We have previously demonstrated that Kruppel-like factor 8 (KLF8) participates in oncogenic transformation of mouse fibroblasts and is highly overexpressed in human ovarian cancer. In this work, we first correlated KLF8 overexpression with the aggressiveness of ovarian patient tumors and then tested if KLF8 could transform human ovarian epithelial cells. Using the immortalized non-tumorigenic human ovarian surface epithelial cell line T80 and retroviral infection, we generated cell lines that constitutively overexpress KLF8 alone or its combination with the known ovarian oncogenes c-Myc, Stat3c and/or Akt and examined the cell lines for anchorage-independent growth and tumorigenesis. The soft agar clonogenic assay showed that T80/KLF8 cells formed significantly more colonies than the mock cells. Interestingly, the cells expressing both KLF8 and c-Myc formed the largest amounts of colonies, greater than the sum of colonies formed by the cells expressing KLF8 and c-Myc alone. These results suggested that
Ovarian transposition is a procedure that can help preserve fertility for female patients requiring radiation in the abdominopelvic region. However, the displacement of ovaries from its original anatomic location can make oocyte retrieval challenging. A 24-year-old nulligravid patient recently diagnosed with colorectal carcinoma [CRC] underwent ovarian transposition prior to radiation. After radiation and chemotherapy, she began in vitro fertilization [IVF] by reproductive endocrinology and infertility physicians. Right ovary demonstrated nonviability due to failed transposition and radiation. Left ovarian oocytes were not able to be harvested due to risk of left kidney puncture via transvaginal ultrasound [TVUS]. Interventional Radiology [IR] was involved and performed a transabdominal ultrasound guided egg retrieval which led to successful IVF. This case highlights the utility of IR-assisted transabdominal ultrasound approach for oocyte retrieval in patients with history of ovarian transposition.
Previous studies from our laboratory showed the involvement of juvenile hormone (JH) and ecdysteroid signaling in the regulation of female reproduction in the red flour beetle, Tribolium castaneum. JH regulates vitellogenin (Vg) synthesis in the fat body but the role of ecdysteroid signaling is not known. Here, we report on ecdysteroid regulation of ovarian growth and oocyte maturation. Microarray analysis of RNA isolated from ovaries showed the up-regulation of several genes coding for proteins involved in ecdysteroid signaling on the 4th day after female adult eclosion. The functional analyses of genes coding for proteins involved in ecdysteroid and JH signaling pathways by RNA interference (RNAi) revealed that ecdysteroids but not JH regulate ovarian growth and primary oocyte maturation. Ultrastructural studies showed the temporal sequences of key events in oogenesis including the development of primary oocytes, the differentiation and development of follicle epithelial cells, and the formation of
Introduction. The gonad arises from the thickening of the coelomic epithelium and then commits into the sex determination process. The Wnts are a family of glycoprotein signalling molecules known mostly for the roles they play in embryonic and ovarian development. Canonical Wnt signalling leads to intracellular accumulation of the multifunctional protein β-catenin which can interact with members of the T-cell factor family to modulate gene transcription. In reviewing the current understanding of ovarian surface epithelium development in the literature, we highlight some previous studies and discuss some of the recent mouse models that have contributed to the understanding of ovarian surface epithelium differentiation.. Conclusion. Taking into account the recent emergence of studies examining Wnt signalling in ovary development and ovarian cancer, the current data suggest that mouse ovarian surface epithelium is heterogeneous in Wnt signalling and may contain a population of stem/progenitor ...
TY - JOUR. T1 - Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis. AU - Capo-Chichi, Callinice D.. AU - Smith, Elizabeth R.. AU - Yang, Dong Hua. AU - Roland, Isabelle H.. AU - Vanderveer, Lisa. AU - Cohen, Cynthia. AU - Hamilton, Thomas C.. AU - Godwin, Andrew K.. AU - Xu, Xiang Xi. N1 - Copyright: Copyright 2019 Elsevier B.V., All rights reserved.. PY - 2002/10/15. Y1 - 2002/10/15. N2 - BACKGROUND. Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a signal transduction protein and a candidate tumor suppressor of ovarian carcinoma, functions in positional organization of ovarian surface epithelial cells. In ovarian carcinomas, genetic and ...
Female Reproductive System Ovaries 1 Female Reproductive System Pregnancy And Childbirth photo, Female Reproductive System Ovaries 1 Female Reproductive System Pregnancy And Childbirth image, Female Reproductive System Ovaries 1 Female Reproductive System Pregnancy And Childbirth gallery
The symptoms of PCOS often date from adolescence and it is no surprise that polycystic ovaries are commonly found in teenagers with menstrual disturbances and/or hirsutism. The typical biochemical abnormalities are often present but it is important to be aware that, as in adults, serum concentrations of LH or testosterone (even in hirsute subjects) may be normal and should not prohibit the diagnosis of PCOS, which is made, primarily, on clinical and ultrasonographic criteria. Polycystic ovaries can be identified on ultrasound, even in prepubertal children. The prevalence of polycystic ovaries increases throughout puberty, reaching 26% by the age of 15.12 Full expression of clinical and endocrine features of polycystic ovary syndrome depends on the maturational changes in the hypothalamic-pituitary-ovarian axis which occur during normal puberty, notably the influence of gonadotrophins on ovarian steroidogenesis. The presence of polycystic ovaries before the onset of puberty suggests that the ...
But no matter how convincing the various information regarding the harmlessness of these follicular cysts on ovaries are, women still do not sleep soundly at night if they know that they have these masses growing within. This is a normal reaction, especially considering the stigma that comes with the the word cyst. Hopefully, these pieces of information would somehow ease the stress of those who were found to be carrying these more-often-than-not-harmless follicular cysts on ovaries ...
Follicle stimulating hormone (FSH) is known as the key hormone capable of causing proliferation of granulosa cells in the ovary. The classical receptor belongs to the G protein-coupled superfamily and is designated FSHR-1. A variant in the FSH receptor has been shown to be functional in mouse ovaries. The variant receptor is designated as FSHR-3, and when bound by FSH activates a pathway that shares similar characteristics to the growth factor type I receptor pathway, with no increase in cAMP. The FSHR-3 variant activates MAPK upon binding to FSH, and causes proliferation of cells on which it is known to be expressed. For example ID8 mouse ovarian surface epithelium cells (MOSEC), a cell line that when introduced in immunocompetent mice causes tumors similar to human ovarian cancer and which also express FSHR-3, proliferated in response to FSH. The present study explored the potential for decreasing expression of FSHR-3 protein. The RNA interference (RNAi) technique was used to insert small ...
Earlier studies have demonstrated that phenol UDP-glucuronosyltransferase (UGT) activity is up-regulated by pregnant mares serum gonadotropin (PMSG) in rat ovary, but not liver. This phenomenon was investigated in more detail in the present study. Ovaries and livers of immature rats, rats synchronized with respect to their preovulatory and corpus lutealphases by treatment with PMSG, and mature rats hyperstimulated with PMSG were compared. Under all of these conditions, only one immunoreactive band of UGT, shown to be phenol UGT, was detected in the rat ovary. The effects of oestradiol, progesterone and/or human chorionic gonadotropin (hCG) on the level of phenol UGT in immature rat ovary were also examined. Partial up-regulation was caused by progesterone or oestradiol, together with hCG, whereas progesterone or oestradiol alone had no up-regulating effect. Follicle-stimulating hormone also seemed to be required for the up-regulation in ovaries enriched in corpus luteum. The present findings ...
Ovarian follicle activation can be defined as primordial follicles in the ovary moving from a quiescent (inactive) to a growing phase. The primordial follicle in the oocyte is what makes up the pool of follicles that will be induced to enter growth and developmental changes that change them into pre-ovulatory follicles, ready to be released during ovulation. The process of development from a primordial follicle to a pre-ovulatory follicle is called folliculogenesis. Activation of the primordial follicle involves the following: a morphological change from flattened to cuboidal granulosa cells, proliferation of granulosa cells, formation of the protective zona pellucida layer, and growth of the oocyte. It is widely understood that androgens act primarily on preantral follicles and that this activity is important for preantral follicle growth. Additionally, it is thought that androgens are involved in primordial follicle activation. However, the influence of androgens on primordial follicle ...
All information about the latest scientific publications of the Clínica Universidad de Navarra. Postpartum ovarian vein thrombosis after cesarean delivery: a case report.
Mutations in human and/or mouse homologs are associated with this disease. Synonyms: Multicystic ovaries; Multicystic ovaries; PCOS; Polycystic Ovarian disease; Polycystic ovaries; Polycystic ovaries (disorder); polycystic ovary; Polycystic ovary syndrome; Stein-Leventhal synd.; Stein-Leventhal synd.; Stein-Leventhal syndrome; Stein-Leventhal syndrome
It has been generally accepted for more than half a century that, in most mammalian species, oocytes cannot renew themselves in postnatal or adult life, and that the number of oocytes is already fixed in fetal or neonatal ovaries. This assumption, however, has been challenged over the past decade. In this study, we have taken an endogenous genetic approach to this question and generated a multiple fluorescent Rosa26rbw/+;Ddx4-Cre germline reporter mouse model for in vivo and in vitro tracing of the development of female germline cell lineage. Through live cell imaging and de novo folliculogenesis experiments, we show that the Ddx4-expressing cells from postnatal mouse ovaries did not enter mitosis, nor did they contribute to oocytes during de novo folliculogenesis. Our results provide evidence that supports the traditional view that no postnatal follicular renewal occurs in mammals, and no mitotically active Ddx4-expressing female germline progenitors exist in postnatal mouse ovaries. ...
Apoplexia of the ovary (apoplexia ovarii) is an acute gynecological disease that results in the rupture of vessels (this may be the vessels of both the ovary itself and the cyst formed), and a sudden hemorrhage develops into the ovarian tissue or into the abdominal cavity.. Anatomy and physiology of ovaries.. The ovaries are a paired organ located on either side of the uterus in a small pelvis. Their average length is 3 cm, the thickness is 1 cm, and the width is 2 cm. But these dimensions are not constant, and vary throughout the month, depending on the phase of the menstrual cycle. Ovaries are female sex glands, they produce sex hormones (progesterone and estrogens), and every month an egg is formed that can give life to a new organism. Ovaries have their own ligaments, with which they attach to the uterus.. The prevalence of the disease.. Apoplexy of the ovary occurs at any age, but most often the gap occurs in women of childbearing period (from 18 to 45 years), because it is at this age that ...
The objective of our research is to determine whether the synchrotron is an effective tool for imaging human ovaries ex situ. Approximately 1 in every 6 women in Canada is affected by infertility; however, the underlying causes remain largely unknown. Imaging techniques are essential for increasing our understanding of normal and abnormal female reproductive biology. At present, ultrasonography is the most commonly-used tool to image human ovaries. However, ultrasonography only allows the detection of structures ≥ 2 mm in size within the ovaries, limiting the ability to detect smaller anatomic details (eg. the eggs and the surrounding cells and follicles or the small fluid filled sacs that contain the eggs). Other limitations of ultrasonography for imaging the ovaries include a limited depth of penetration within the pelvis and the inability to see the ovaries clearly due to bowel activity and/or gas.. The synchrotron has been effectively used for imaging soft tissues, including the breast, ...
Aromatase plays a key role in sex differentiation of gonads. In this study, we cloned the full-length cDNA of ovarian aromatase from protogynous hermaphrodite red-spotted grouper (Epinephelus akaara), and prepared the corresponding anti-EaCyp19a1a antiserum. Western blot and immunofluorescence studies revealed ovary-specific expression pattern of EaCyp19a1a in adults and its dynamic expression change during artificial sex reversal. EaCyp19a1a was expressed by follicular cells of follicular layer around oocytes because strong EaCyp19a1a immunofluorescence was observed in the cells of ovaries. During artificial sex reversal, EaCyp19a1a expression dropped significantly from female to male, and almost no any positive EaCyp19a1a signal was observed in testicular tissues. Then, we cloned and sequenced a total of 1967 bp T-flanking sequence of EaCyp19a1a promoter, and showed a number of potential binding sites for some transcriptional factors, such as SOX5, GATA gene family, CREB, AP1, FOXL1, C/EBP, ...
course on the cryopreservation & transplantation of human ovarian tissue as well as preantral follicle isolation & in vitro culture
DESCRIPTION (provided by applicant): This proposal requests renewal for years 21-25 of the P01 program Hormonal Signals that Regulate Ovarian Differentiation at Northwestern University. The program has a long history of collaborative discovery-based research in the reproductive sciences that has led to numerous scientific breakthroughs over the lifetime of the grant. The major theme of the program is to investigate signaling pathways by which hormones or other regulatory factors act on the ovary to promote steroidogenesis and the maturation of follicles and germ cells necessary to sustain female fertility. To investigate this theme, 3 new research projects are proposed that represent novel and creative research directions inspired by our progress during the last grant period and by our most recent preliminary findings. Project 1 (Kelly Mayo and Teresa Woodruff) focuses on ovarian development and the events that regulate the breakdown of germ cell nests to form the initial pool of primordial ...
Transforming growth factor-β (TGF-β) superfamily is a group of about 35 proteins involved in pre- and postnatal physiological processes.56 Members of this superfamily are expressed by oocytes and ovarian somatic cells in key developmental stages.57, 58, 59, 60, 61 Throughout life ovarian follicles leave the resting pool to join the growing pool. The precise mechanism of follicular recruitment is not fully elucidated, however, members of the TGF-β family are involved in the process. Bone morphogenetic proteins (BMP) 7 and 4 promote primordial to primary follicle transition.62 Similarly, anti-Mullerian hormone (AMH), another member of the TGF-β superfamily, is involved in initiation of primordial follicle growth.63 Progression of primary follicles to early antral stage is enhanced by growth and differentiation factor-9 (GDF-9) and BMP-15 of oocyte origin, activins of granulosa origin, and BMP-4 and BMP-7 of thecal origin.61 Antral follicle growth and follicle selection mechanism involves the ...
Synonyms for primary oocyte in Free Thesaurus. Antonyms for primary oocyte. 1 word related to oocyte: gametocyte. What are synonyms for primary oocyte?
Clusters of primordial germ cells (PGCs) with somatic cells come closer to form ovigerous cords, which is first discernible in the fetal ovary upon establishment of initial contact between germ cells and somatic cells near the surface of the ovarian epithelium.. The first mechanistic difference between an XX and an XY germ cell in the genital ridge is reactivation of the inactive X in the female PGCs. The XX germ cells continue to divide and then enter meiosis at around E12.5. Subsequently, the female germ cells arrest at the diplotene stage of meiosis I and do not resume meiosis until postnatal ovarian folliculogenesis.. Folliculogenesis: Before formation of an ovarian follicle, oocytes are present within germ cell clusters (cysts or nests). The first stage of ovarian folliculogenesis involves the formation of the primordial follicle, which occurs when oocytes that survive the process of germ cell cluster breakdown are individually surrounded with squamous pre-granulosa cells. This takes place ...
Factors that cause some primordial follicles to enter the growth phase while the others remain quiescent are unknown. The hypothesis was tested that primate primordial follicles can survive and initiate growth in vitro in serum-free medium. Superficial pieces of ovarian cortex, containing mostly primordial follicles, were obtained from baboon fetuses during late gestation and cultured for 0, 2, 4, 7, 10 or 20 days in Waymouth MB 752/1 medium supplemented with insulin, transferrin, selenium, linoleic acid, and bovine serum albumin (ITS +). Histological examination of cortical pieces revealed that after 2 and 4 days in culture, the total number of primordial follicles had decreased by 55 and 76% (P | 0.01) respectively, relative to day 0 of culture. This was associated with a sustained, 5- to 8-fold increase in total primary follicles (P | 0.01) beginning on day 2 of culture. There was also a gradual increase in the total number of early secondary and secondary follicles. The average
The imagined of enduring cysts during your sx gland is scary and difficult. This is considered to be true, regardless of the the situation that your are prevailing occurrences into women that are throughout the their child-bearing years. Subsequently after all, would you wants that can have a new great unknown and as well seemingly risking mass maturing inside my core ones method system? It all is, therefore, a favourable idea toward know which will not the entire cysts get out so that you get you will. If anything, they may possibly just seem part in what means you one woman.. Understanding Very easy Cysts entirely on Ovaries. So what on earth are growths? Cysts actually are essentially one collection off fluid adorned by a nice thin membrane, and these types of people grow from or on a the sx gland of ladies who. In normally , cases, here sacs most likely will be to mainly because simple - cysts through to ovaries that particular grow simple fact of our normal menstruation cycle. ...
Female sex cells, or gametes, develop in the ovaries by a form of meiosis called oogenesis. The sequence of events in oogenesis is similar to the sequence in spermatogenesis, but the timing and final result are different. Early in fetal development, primitive germ cells in the ovaries differentiate into oogonia. These divide rapidly to form thousands of cells, still called oogonia, which have a full complement of 46 (23 pairs) chromosomes. Oogonia then enter a growth phase, enlarge, and become primary oocytes. The diploid (46 chromosomes) primary oocytes replicate their DNA and begin the first meiotic division, but the process stops in prophase and the cells remain in this suspended state until puberty. Many of the primary oocytes degenerate before birth, but even with this decline, the two ovaries together contain approximately 700,000 oocytes at birth. This is the lifetime supply, and no more will develop. This is quite different than the male in which spermatogonia and primary spermatocytes ...
To determine the intracellular gene targets of P4 in non-neoplastic OSE cells, we analyzed changes in gene expression patterns in six independent short-term cultures using genome-wide transcript arrays. We found a highly statistically significant regulation of transcripts involved in cholesterol metabolism. For example, multiple transcripts representing cholesterol-homeostasis genes including HMGCS1, HMGCR, IDI1, FDPS, FDFT1, NSDHL, EBP, DHCR7, INSIG1, FADS1 were upregulated by P4 exposure (Additional File 2). Examination of each experimental pair revealed that the transcriptional activity induced by P4 exposure originated only from three of the six experimental pairs. Re-analysis of these three responder pairs uncovered a functionally uncharacterized gene TMEM97 as the most-responsive transcript which showed a 1.95-fold increase upon P4 exposure. Examination of genome-scale, tissue-specific gene expression levels in the GNF2 database uncovered a strong correlation between TMEM97 and cholesterol ...
List the changes the primary oocyte underqoes in the tertiary follicular stage in the human ovary - Biology - Human Reproduction
The reproductive cycle can be divided into an ovarian cycle and a uterine cycle (compare ovarian histology and uterine histology in the diagram on the right). During the uterine cycle, the endometrial lining of the uterus builds up under the influence of increasing levels of estrogen (labeled as estradiol in the image). Follicles develop, and within a few days one matures into an ovum, or egg. The ovary then releases this egg, at the time of ovulation. After ovulation the uterine lining enters a secretory phase, or the ovarian cycle, in preparation for implantation, under the influence of progesterone. Progesterone is produced by the corpus luteum (the follicle after ovulation) and enriches the uterus with a thick lining of blood vessels and capillaries so that it can sustain the growing fetus. If fertilization and implantation occur, the embryo produces Human Chorionic Gonadotropin (HCG), which maintains the corpus luteum and causes it to continue producing progesterone until the placenta can ...
Though the authors insisted that instructions for collecting and submitting your urine are simple, modern readers might disagree. I feel amazing 90 of the time, there is that 10 when Im very uncomfortable but that is bound to happen, I have a human living inside me, haha. There may also be a change in mood, a feeling of fatigue, or simply somehow feeling different. Understand that youre not alone. Looking back now, after having information about HELLP syndrome (Ive spent hours reading about it on internet websites) I had a lot of corpus luteal cyst right ovary during pregnancy of this that could have possibly allowed me to prolong my delivery had it been caught. Waiting at least a week after a missed period may give you the most accurate result. In some women, more frequent urination starts even before they miss the period. It isnt attainable to know forward of time exactly what corpus luteal cyst right ovary during pregnancy being pregnant and labor can be like. Hysterectomy involves the ...
The present study investigated the efficiency of saline solution and coconut water solution in the preservation of goat preantral follicles enclosed in ovarian tissue, at different temperatures and for different incubation periods. At the slaughterhouse, the ovarian pair was divided into 19 fragments; one ovarian fragment was immediately fixed for histology (control-time zero). The other 18 ovarian fragments were preserved in both solutions at 4ºC, 20ºC or 39ºC for 4 h, 12 h or 24 h. The histological analysis showed that the storage of ovarian fragments in both solutions at 4ºC for up to 24 h kept the percentage of normal preantral follicles similar to the control values. In contrast, preservation at 20°C or 39ºC, in either solution, reduced significantly the percentage of normal preantral follicles compared to the control values, except in saline solution at 20ºC for 4 h or in coconut water solution at 20ºC for 4 h and 12 h. In conclusion, this study shows that both solutions can be ...
I prefer to end my week either on a high note or hell, why not just high.. However, since Im now a responsible adult with a child, Ill be selecting the high note.. There are several tests out there to help physicians determine a womans Ovarian Reserve (cache of eggs). We have the AFC: Antral Follicle Count - Presumably, the number of antral follicles visible on ultrasound is indicative of the relative number of microscopic (and sound asleep) primordial follicles remaining in the ovary. Each primordial follicle contains an immature egg that can potentially develop in the future. In other words, when there are only a few antral follicles visible, there are less eggs remaining as compared to when there are more antral follicles visible. As women age, they have less eggs (primordial follicles) remaining, therefore they have less antral follicles visible on ultrasound. (1). We have the CD3 FSH:. Day 3 Follicle Stimulating Hormone - By measuring a baseline FSH on day 3 of the cycle (we do it on ...
Synonyms for accessory ovary in Free Thesaurus. Antonyms for accessory ovary. 14 words related to ovary: blossom, flower, bloom, reproductive structure, placenta, craniate, vertebrate, arteria ovarica, ovarian artery.... What are synonyms for accessory ovary?
Lipid cell tumors of the ovary are among the rarest of the functional ovarian neoplasms. Recently, authors experienced a case of lipid cell tumor of the left ovary in a 19 year old female, who presented with amenorrhea and hirsutism for 4 years. Grossly, the ovary was well encapsulated, and measured 6.5x6x4.5 cm. Cut surface show homogenous yellowish bulging neoplastic tissue and peritheral displaced normal ovarian tissue. Microscopically, neoplastic cells were composed of rounded and polyhedral cells, arranged in nests seperated by rich vascular networks. On the basis of the authors findings and the evidence available in the literature, we determined this case as ovarian lipid cell tumor. ...
Use of intra-articular and intrabursal pulsed radiofrequency for the treatment of persistent arthrogenic shoulder pain. Pain Med. 2013 Apr; 14(4):554-6 ...
The risk rises with age, with around nine in 10 women being over 45. There are several other risk factors, the most important being a history in your close family - as 5-10 per cent of women with ovary cancer have inherited a damaged BRCA1 or BRCA2 gene, which makes this cancer more likely. If your mother has had ovary cancer your risk is six times that of the average woman and if your sister has had it your risk is nearly four times the average. If two close relatives have had it, you have a two in five risk of getting it - which is very high, so its essential to see a gynecologist to discuss screening. Sometimes a high risk of both ovary and breast cancers or of ovary and colon cancers, runs in families. ...
FR] Le but de cette étude est de comparar leffet de p/usieurs doses de PMSG injectées a des lapines de race Néo-zélandais Blanc, sur la réponse ovarienne, le taux dembryons récupérés et /eur croissance in vitro. Trente neuf lapines primipares, non allaitantes, ont regu le 2~me jour post partum une injection intramusculaire du traitement suivant: Lot 1 (n=13) O, 1 mi deau distillée; Lot 2 (n=13): 20 Uf de PMSG; Lot 3 (n=13): 100 U/ de PMSG. Soixante douze heures apres, les lapines ont regu 0,8 μg de GnRH et ont été artificiellement inséminées. Les lapines ont été sacrifiées 48 heures apres linsémination ; le tractus génital pré/evé a été conservé dans la solution tampon phosphato-sa/ine de Dulbecco. Les ovaires ont été pesés et les follicu/es normaux non ovulés , 1mm (AF), les fo/Jicules hémorragiques (HF) et les corps jaunes ont été comptés. Les oviductes ont été lavés avec du TCM199 et on a évalué la morpho/ogie des embryons. Les zygotes ont été ...
the reason why women are different from men, is the inherent chromosome, the external genital organs, centered in the central part of the ovary. because of ovarian hormone secretion diligently, in order to maintain the development of reproductive organs, from the inside to show the feminine. women from birth to old, ovary is not the full role in the play, but she has been in the company, even has quietly to sleep, no function, still stubbornly nest deep in the body, never abandon. the life of a woman is a reduced version of a womans life infants and young children, the children grow up slowly, the ovary is, but at this time the ovary can not secrete hormones, but in the long. generally after the age of 8, the ovary began to produce sex hormones, puberty began to develop, menstruation, and this is the menstrual cycle of ovarian hormones secreted by the changes in the endometrium. women of childbearing age can give birth to life, this stage is also the most exuberant period of ovarian vitality. ...
Learn about the veterinary topic of Cystic Ovary Disease in Mares. Find specific details on this topic and related topics from the Merck Vet Manual.
Science fiction meets biology meets medicine. Researchers at Northwestern University presented findings in April 2016 at the Annual Endocrine Society Meeting where they created a prosthetic ovary using a 3D printer and implanted it into mice. The hope of this seemingly Frankenstein-esque procedure is to be able to provide fertility to woman who have lost the use of their ovaries due to processes such as trauma, chemotherapy, radiation or resection.. The process begins by printing a scaffold out of gelatin (made from animal collagen). What makes this step crucial is related to the physical properties of human ovaries. When eggs mature in the ovaries, they grow. Once the egg is released, the remaining products (corpus luteum) remains behind to secrete hormones to allow for development of the embryo. Therefore, the scaffold cannot be rigid, but allow for expansion and contraction of the eggs. Not only does the scaffold have to house the growing eggs, but there also has to be room for blood vessels ...
Guinea pigs, also referred to as cavies, have reproductive organs that can become infected. Learn all about cystic ovaries in them and how to fix them.
Question - Have had fibroid, cystic ovaries, menopausal. Had pre cancer cell removed. Done ultrasound. Recovery from invasive surgery?. Ask a Doctor about diagnosis, treatment and medication for Uterine fibroid, Ask an Oncologist
24 yrs old Female asked about Poly cystic ovary, 2 doctors answered this and 85 people found it useful. Get your query answered 24*7 only on | Practo Consult
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ion - all this also leads to diseases of the genital glands, one of the symptoms of which are a pain in these womens bodies.. How ovary pain?Is it possible to distinguish the pain from the symptoms of other diseases?In the early stages, if the ovary hurts, it is difficult to correctly diagnose ovarian inflammation.Therefore, it is easy to miss the start of the disease, so as not to give her to develop into cancer.Among the first signs of inflammation in the ovary can be attributed an increase in the stomach and aching, nagging pain in his bottom.It increases because fluid accumulates inside can not get out without the intervention of doctors.If a sex gland is inflamed, there may be the appearance of the asymmetry of the abdomen.Often the pain may be accompanied by insomnia, decreased immunity and performance, irritability and other symptoms of mental and physical exhaustion.Other signs of the inflammatory process in appendages are isolation, the failure of the menstrual cycle, discomfort during ...
Section of the ovary of a newly born child. Germinal epithelium is seen at top. Primitive ova are seen in their cell-nests. The Genital cord or genital ridge is still discernible in this young child. A blood vessel and an ovarian follicle is also seen. Formation of about 30 primordial follicles in the ovarian cortex region during 5-7 month of embryonic development ...
Section of the ovary of a newly born child. Germinal epithelium is seen at top. Primitive ova are seen in their cell-nests. The Genital cord or genital ridge is still discernible in this young child. A blood vessel and an ovarian follicle is also seen. Formation of about 30 primordial follicles in the ovarian cortex region during 5-7 month of embryonic development ...
In January 2017, Drs. Donahoe and David Pépin stunned the scientific community with the discovery that AMH/MIS can function both as a contraceptive agent and as an agent which can protect the ovarian reserve during chemotherapy. Their research team showed that MIS can block primordial follicle activation, thereby inhibiting the first step of folliculogenesis and reproduction. Reduction in the number of growing follicles leads to a phenotype of smaller ovaries in the body. This increase in AMH does not reduce the number of primordial follicles, rather it prevents follicular loss. It also can provide contraception without removing reserve oocytes - or immature, female germ cells - during chemotherapy, so natural reproduction can still occur. In mice, treatment with MIS has now been shown to protect the ovarian reserve. As a result, MIS proves to be a reversible contraceptive that functions to mitigate potentially negative effects that chemotherapy may have on mice [7]. Ongoing studies on larger ...
Left Ovary Ovaries Ovarian reserve Folliculogenesis Oophorectomy Ovarian drilling Artificial ovary Ovary culture Colvin, ... There is an ovary (from Latin ovarium 'egg, nut') found on each side of the body. The ovaries also secrete hormones that play a ... The ovaries are uncovered in the peritoneal cavity but are tethered to the body wall via the suspensory ligament of the ovary ... Ovaries in females are analogous to testes in males, in that they are both gonads and endocrine glands. Ovaries of some kind ...
An artificial ovary is a potential fertility preservation treatment that aims to mimic the function of the natural ovary. ... Artificial ovaries could be an effective alternative in fertility preservation. The artificial ovary aims to replicate its ... The microenvironment of the structure should mimic that of the natural ovary, so the artificial ovary should support the ... Included in these are fibrin, alginate and decellularized human ovary which have shown in vitro maturation, ovary-like ...
An ovary is a reproductive organ in female vertebrate. Ovary may also refer to: Ovary (botany), reproductive organ in plants ... This disambiguation page lists articles associated with the title Ovary. If an internal link led you here, you may wish to ...
If the ovary is situated above the insertion point, it is superior; if below, inferior. A superior ovary is an ovary attached ... The syncarpous ovary of this melon is made up of four carpels, and has one locule. In this Peganum harmala, the ovary of a ... The ovary of some types of fruit is dehiscent; the ovary wall splits into sections called valves. There is no standard ... Examples of this ovary type include the legumes (beans and peas and their relatives). A half-inferior ovary (also known as " ...
Polycystic Ovaries: Ovaries might get enlarged and comprise follicles surrounding the eggs. As result, ovaries might fail to ... Polycystic ovaries develop when the ovaries are stimulated to produce excessive amounts of androgenic hormones, in particular ... It is common to have polycystic ovaries without having PCOS; approximately 20% of European women have polcystic ovaries, but ... Transvaginal ultrasound scan of polycystic ovary Polycystic ovary as seen on sonography Other causes of irregular or absent ...
The medulla of ovary (or Zona vasculosa of Waldeyer) is a highly vascular stroma in the center of the ovary. It forms from ... ovary, medulla and cortex" Histology image: 83_02 at the University of Oklahoma Health Sciences Center Portal: Anatomy v t e ( ...
The stroma of the ovary is a unique type of connective tissue abundantly supplied with blood vessels, consisting for the most ... The stroma of the ovary may contain interstitial cells resembling those of the testis. stroma (disambiguation) Stromal cell Sex ...
The follicular cyst of the ovary is a type of functional simple cyst, and is the most common type of ovarian cyst. Its rupture ... Retrieved July 2012 "Follicular cyst of the ovary definition". MedTerms. "Ovarian Cysts". The Institute for Female Alternative ... can create sharp, severe pain on the side of the ovary on which the cyst appears. This sharp pain (sometimes called ...
The suspensory ligament of the ovary is one continuous tissue that connects the ovary to the wall of the pelvis. There are ... Ligament of ovary This article incorporates text in the public domain from page 1254 of the 20th edition of Gray's Anatomy ( ... In the more posterior region, the suspensory ligament is attached to the upper pole of ovary and infundibulum of fallopian tube ... The prenatal development of the suspensory ligament of the ovary is a part of the development of the reproductive system. ...
Chinese hamster ovary (CHO) cells are an epithelial cell line derived from the ovary of the Chinese hamster, often used in ... "CHO cells - 7 facts about the cell line derived from the ovary of the Chinese hamster". evitria AG. 3 May 2022. Lewis NE; Liu X ... Furthermore, Chinese hamster ovary cells are able to produce proteins with complex glycosylations, post-translational ... George Yerganian's laboratory at the Boston Cancer Research Foundation and used it to derive the original Chinese hamster ovary ...
Resistant ovary syndrome, previously known as Savage syndrome, is a cause of ovarian failure that can lead to secondary ... Resistant ovaries result from a functional disturbance of the gonadotropin receptors in the ovarian follicles. It may be a ...
Infertility in polycystic ovary disease (PCOS) is a hormonal imbalance in women that is thought to be one of the leading causes ... Polycystic ovary syndrome causes more than 75% of cases of anovulatory infertility. Not all women with PCOS have difficulty ... ISBN 978-0-07-149868-5. Qiao, J.; Feng, H. L. (2010). "Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on ... Tang, T.; Balen, A. H. (2012). "Use of metformin for women with polycystic ovary syndrome". Human Reproduction Update. 19 (1): ...
... (TCC of the ovary) is a rare type of ovarian cancer that has an appearance similar to ... These tumours do better than other types of epithelial tumours of the ovary. Brenner tumour Tazi, EM.; Lalya, I.; Tazi, MF.; ... Apr 2004). "Transitional cell carcinoma of the ovary: a morphologic study of 100 cases with emphasis on differential diagnosis ... Ahellal, Y.; M'rabti, H.; Errihani, H. (2010). "Transitional cell carcinoma of the ovary: a rare case and review of literature ...
Development of the Mammalian Ovary and Follicles", The Ovary (Third Edition), Academic Press, pp. 71-82, ISBN 978-0-12-813209-8 ... The tunica albuginea is a layer of condensed fibrous tissue on the surface of the ovary. The tunica albuginea is composed of ... It is thinner than the tunica albuginea of the testis, and its thickness varies across the ovary. The tunica albuginea is ...
"Play synopsis for two That Takes Ovaries plays , That Takes Ovaries". "That Takes Ovaries mission, ... "That Takes Ovaries"-A Play for the Bold and Brazen - Ms. Magazine". Ringger, Lauren. "Now {that} takes ovaries ... That Takes Ovaries': A tribute to strong women , The Northern Light". "Deconstructing That Takes Ovaries". Radcliffe Institute ... "Records of That Takes Ovaries, 2002-2010 (MC 746)". Flickr. moniqueღ, jianda (August 10, 2013). "That Takes Ovaries". Medium. " ...
... ovary crested. The plant is named in honor of B. L. Robinson of the Gray Herbarium of Harvard University. The leaves are flat ...
5. Ovary. 6. Longitudinal section of ovary all magnified. 7. Ripe fruit. 8. The same with most of the carpels removed, showing ...
... inferior ovary. Fruits in berries, coriaceous. Species include: List: Psammisia of Ecuador Media related to Psammisia at ...
Ovary superior. Carpels 3 to 20, in 1 (rarely 2) whorls, free or basally connate. Ovules 12 to 100 per carpel and scattered ...
The ovary are under constant. A large part of the species blooms at night. The flower formula is: ⋆ {\displaystyle \star } bis ... inferior ovary . There are three sepals present. The three petals often have different shades of blue, there are also yellow, ...
Tepals are translucent white with green midveins; anthers yellow; ovary green. Ori Fragman-Sapir & Reinhard M. Fritsch. 2012. ...
Ovary glabrous; style 7-9 mm long, longer than the smaller stamens, cylindrical, glabrous, curved near apex, closely appressed ...
Ovary multilocular. - Ovules basal, erect, 1 per locule. - Fruit a small drupe, usually blue. Pyrenes with thick walls. The ...
... ovary superior. The fruits are smooth, paired and horn-shaped, 10-22 cm × 1.5-3 cm, dehiscing to release multiple winged seeds ...
Ovary green. subspecies Allium decipiens subsp. decipiens - Ukraine, European Russia, Western Siberia, Altay Krai, Caucasus, ...
Flowers bell-shaped, up to 6 mm across; tepals pink; anthers and pollen pale yellow; ovary crested. Flora of North America, v ...
... ovary bilocular. Fruit a corky berry. Species in cultivation include Brunfelsia americana and Brunfelsia pauciflora. Brunfelsia ...
Ovary sessile; stigmas small, dish-shaped or capitate. Fruits are fleshy, globose, rarely ellipsoid or oblong, subtended at ...
I) Flower hypogynus; ovary superior. I) Stamens indefinite, monadelphous. II) Ovary 5 carpellary, placentation axile. I) Plant ... Carples: five, syncarpous, ovary superior, penta or multilocular with axile placentation, one ovule in each locule; style 1, ...
Ovary striate. pubescent. Tube recurved. Strip very dilated, with two cordate and very developed auricles. Outer. part greenish ...
Polycystic ovary syndrome is a condition that affects women in their child-bearing years and alters the levels of multiple ... In polycystic ovary syndrome, one or both ovaries can contain multiple small, immature ovarian follicles that can appear as ... Polycystic ovary syndrome is the most common cause of infertility due to absent ovulation. The prevalence of polycystic ovary ... Polycystic ovary syndrome is a condition that affects women in their child-bearing years and alters the levels of multiple ...
Multiple small cysts on the ovaries. Just having ovarian cysts isnt enough for a diagnosis. Lots of women without PCOS have ... Ever heard of polycystic ovary syndrome (PCOS)? If youre a woman who has had trouble getting pregnant, you might have. Just ... cysts on their ovaries and lots of women with PCOS dont have cysts. ...
Learn about the possible causes of ovary pain, including cysts and endometriosis. ... The ovaries are located on either side of the lower pelvis. ... Causes of ovary pain. Here are seven of the most common causes ... Torsion is more common if there is a cyst on the ovary because the cyst makes the ovary heavier or larger than usual. ... The ovaries are two small glands situated on either side of the lower pelvis. They play a vital role in reproduction, the ...
We are particularly focused on understanding how brain wiring and communication is altered in Polycystic Ovary Syndrome (PCOS ...
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. A leading cause of infertility ... Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome ... Heritability of polycystic ovary syndrome in a Dutch twin-family study. J Clin Endocrinol Metab. 2006 Jun;91(6):2100-4.Full ... Prevalence of polycystic ovary syndrome in women from opposite-sex twin pairs. J Clin Endocrinol Metab. 2009 Jun;94(6):1987-90. ...
... an ovary composed of more than one carpel. See more. ... Words nearby compound ovary. compound leaf, compound lens, ... compound magnet, compound microscope, compound number, compound ovary, compound pendulum, compound Q, compound sentence, ...
This patient FAQ provides information on causes and treatment of polycystic ovary syndrome. ...
The ovary and ovarioles of mosquitos (‎an illustrated note, with glossary)‎ / by D. S. Bertram  ...
Both ovaries are usually involved. When the stromal hyperplasia is prominent, the affected ovaries are enlarged, and display ... In: Pathology of the Ovary. Philadelphia, PA: Saunders; 2004:208-217.. *Scully, RE, Young, RH, Clement, PB. Tumors of the Ovary ... The involved ovary ranges in size from 8.0 to 14.0 cm and is white with smooth or lobulated outer surfaces. The cut surfaces ... The involved ovary is usually enlarged (average 11.5 cm in diameter) and soft, and the cut surfaces are gelatinous and ...
Herein, we present a case of borderline clear cell adenofibroma of the ovary in a 58-year-old woman who presented with a pelvic ... The pathological diagnosis was borderline clear cell adenofibroma of the left ovary. There was no reoccurrence 36 months post ... The diagnoses of borderline clear cell adenofibroma of the left ovary and benign serous tumor of the right ovary were made ... T. A. Longacre and M. Wells, "WHO classification of tumours of the ovary," in World Health Organization Classification of ...
Next thing you know is her ovary is giving it to nolan from the back. ...
PRNewswire-USNewswire/ -- PCOS Challenge: The National Polycystic Ovary Syndrome Association worked with U.S. Congressman David ... PCOS Challenge: The National Polycystic Ovary Syndrome Association May 02, 2018, 08:12 ET ... WASHINGTON, May 2, 2018 /PRNewswire-USNewswire/ -- PCOS Challenge: The National Polycystic Ovary Syndrome Association worked ... PCOS Challenge: The National Polycystic Ovary Syndrome Association. (404) 855-7244. SOURCE PCOS Challenge: The National ...
The Drosophila ovary : An in vivo stem cell system. Xie T, Spradling AC. In: DR Marshak, RL Gardner, and D Gottlieb, eds. Stem ...
Angelina Jolie Had Ovaries & Fallopian Tubes REMOVED!. by Jack After having a masectomy, Angelina Jolie makes another brave ... Filed Under: Tid Bits & News Tagged With: Angelina Jolie, cancer, fallopian tubes, ovaries, remove ... decision: deciding to have her ovaries and fallopian tubes removed.. [Read more…] about Angelina Jolie Had Ovaries & Fallopian ...
... polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, oligo-anovulation and polycystic ovarian morphology. It ... Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation Reprod Biol Endocrinol. 2022 Jan 10;20(1 ... As a common endocrinopathy of reproductive-aged women, polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, ...
Early surgical menopause is the removal of both ovaries before natural menopause and often accompanies a hysterectomy. ...
Polycystic ovary syndrome (PCOS) is a hormonal disorder causing irregular menstruation and other symptoms. Reviewed by a board- ... Polycystic Ovary Syndrome (PCOS). Fertility Diagnosis Symptoms & Causes Nutrition & Weight Loss Treatment Living With Support ... How is polycystic ovary syndrome (PCOS) treated? There is no cure for PCOS, but its symptoms can be managed with weight loss, ... What causes polycystic ovary syndrome (PCOS)? Researchers dont know the exact cause of PCOS, but an endocrine system imbalance ...
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Ovary - Atrophy in a female F344/N rat from a chronic study. The ovary is small and lacking follicles and corpora lutea. ... Ovary - Atrophy in a female F344/N rat from a chronic study. The ovary is small and lacks follicles and corpora lutea. ... Ovary - Atrophy in a female F344/N rat from a chronic study (higher magnification of Figure 1). There are few follicles, and no ... Changes in the ovary. In: Pathobiology of the Aging Mouse (Mohr U, Dungworth DL, Capen CC, Carlton WW, Sundberg JP, Ward JM, ...
The ovaries and fallopian tubes, however, may also undergo malignant transformation, and the hormones secreted by the ovary ... the ovaries are typically retained. The case seems easy for menopausal women as well. In their case, the ovary no longer serves ... The ovaries serve an important endocrine function, and their proper activity during the reproductive years is associated with ... Removal of the still-active ovaries should reduce the risk for cancers in which hormones play a role in the etiology. Simple ...
Women who have their healthy ovaries removed when they have a hysterectomy face a higher risk of death, including death from ... Of the 600,000 women in the United States who get a hysterectomy every year, about 300,000 also have their ovaries removed- ... Though the risk of ovarian and breast cancer declined after ovary removal, womens risk of heart disease and stroke nearly ... Doctors have recommended for decades that women who get a hysterectomy consider having both ovaries removed-a surgical ...
Actress Keke Palmer revealed that she has been diagnosed with polycystic ovary syndrome. Here is what we know about the ... What is polycystic ovary syndrome?. According to the Mayo Clinic, polycystic ovary syndrome (PCOS) is a hormonal disorder that ... Polycystic Ovary Syndrome: What is the condition Keke Palmer revealed she has?. Wed Dec 02, 2020 at 12:16pm ET. By John Thomas ... She revealed she had suffered from polycystic ovary syndrome for her "entire life," but she was not properly diagnosed until ...
Researchers have developed a protective strategy that aids in the shielding of female mammals ovaries from damaging effects of ... Primate ovaries are free of any such enclosure, presenting the risk that any protective agent applied to the ovary might escape ... Study Says Ovaries Must Suppress Their Inner Male. A study in the December 11th issue of the journal Cell , a Cell Press ... Women Asked to Freeze Ovaries in 20s. Women can increase the chances of giving birth to a child later in their life by freezing ...
Chinese Hamster Ovary Cells, Specimen 3. Chinese Hamster Ovary Cells, Specimen 3. Most animal cells display a finite lifetime ...
Dynamic Model of Chinese Hamster Ovary Cell Metabolism in Fed-Batch Culture. Nolan, Ryan. ...
... Condition Basics. What is polycystic ovary syndrome (PCOS)?. Polycystic ovary syndrome (PCOS ... What does a polycystic ovary look like?. In polycystic ovary syndrome, cysts may form on the ovaries. A cyst is a sac-shaped ... Most of those who have PCOS grow many small cysts on their ovaries. Thats why its called polycystic ovary syndrome. ... Polycystic ovary syndrome (PCOS) causes a wide range of symptoms, so it may be hard to know when to see your doctor. But early ...
Insulin-sensitizing drugs can help thin women with polycystic ovary syndrome even if they do not appear to be insulin resistant ... Ovaries, Ovulation, Placebo, Polycystic Ovary Syndrome, Research, Testosterone ... Insulin sensitizing drugs help thin women as well overweight women with polycystic ovary syndrome. *Download PDF Copy ... Polycystic ovary syndrome is the most common reproductive syndrome in women, affecting between 6 percent and 10 percent of ...
I have a patient with polycystic ovary syndrome (PCOS) .Now is the 4th year of her disease .She have menstrual irregularities ... I was diagnosed via ultrasound with PCOS (lots of little cysts were hanging out in my ovaries). It does run in my family, and ... Only minimal damage to the ovary is required to stimulate ovulation. The method involves 4-point diathermy set at 40 W for 4 ... I have a patient with polycystic ovary syndrome (PCOS) .Now is the 4th year of her disease .She have menstrual irregularities ...
Polycystic ovary syndrome (PCOS) is a complex disorder that affects many women during their childbearing years. Learn about ... Polycystic Ovary Syndrome Polycystic ovary syndrome (PCOS) develops in women of childbearing age who produce a higher-than- ... Polycystic ovary syndrome is a complex disorder that isnt fully understood. Some research links PCOS to high levels of insulin ... Many women with PCOS also develop non-cancerous cysts in their ovaries, although this isnt always the case. PCOS Causes ...
Learn about polycystic ovary syndrome (PCOS) and how this condition is treated at LVHN. ... Polycystic ovary syndrome (also called PCOS, Stein Leventhal syndrome, polycystic ovary disease or POD) is the most common ... Many small cysts (fluid-filled sacs) on the ovaries Researchers dont yet know the exact cause of PCOS, but they know it runs ... Learn about polycystic ovary syndrome (PCOS) and how this condition is treated at LVHN. ...
  • Ever heard of polycystic ovary syndrome (PCOS)? (
  • Lots of women without PCOS have cysts on their ovaries and lots of women with PCOS don't have cysts. (
  • We are particularly focused on understanding how brain wiring and communication is altered in Polycystic Ovary Syndrome (PCOS), a common endocrine disorder characterised by androgen excess. (
  • The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. (
  • As a common endocrinopathy of reproductive-aged women, polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism, oligo-anovulation and polycystic ovarian morphology. (
  • Polycystic ovary syndrome (PCOS) is a condition that affects about one in 10 women of childbearing age and can impair fertility. (
  • How is polycystic ovary syndrome (PCOS) treated? (
  • How is polycystic ovary syndrome (PCOS) diagnosed? (
  • Having polycystic ovary syndrome (PCOS) can make it difficult to lose weight due to hormonal imbalances and insulin resistance. (
  • Having polycystic ovary syndrome (PCOS) can make getting pregnant difficult. (
  • Polycystic ovarian syndrome (PCOS) is a common condition where the ovaries produce excess male sex hormones called androgens, which causes hormonal imbalances that can lead to a range of symptoms. (
  • Could your irregular menstrual cycles, infertility, acne, and excess facial hair be caused by polycystic ovary syndrome (PCOS)? (
  • Keke Palmer (Lauren Keyana Palmer) revealed she was diagnosed with a medical condition known as polycystic ovary syndrome (PCOS). (
  • According to the Mayo Clinic , polycystic ovary syndrome (PCOS) is a hormonal disorder that affects women of reproductive age. (
  • Polycystic ovary syndrome (PCOS) is a health issue that can affect women and teens of the reproductive age. (
  • In all women with PCOS, the ovaries don't work very well. (
  • However, the ovary in a woman who has PCOS makes many small follicles instead of one big one. (
  • Who gets polycystic ovary syndrome (PCOS)? (
  • What are the signs and symptoms of polycystic ovary syndrome (PCOS)? (
  • Polycystic ovary syndrome (PCOS) is a hormone imbalance that can affect ovulation. (
  • Most of those who have PCOS grow many small cysts on their ovaries. (
  • Polycystic ovary syndrome (PCOS) causes a wide range of symptoms, so it may be hard to know when to see your doctor. (
  • Women with PCOS have enlarged ovaries - the organs that produce eggs - that become host to fluid-filled sacs or cysts. (
  • Polycystic ovary syndrome (PCOS) develops in women of childbearing age who produce a higher-than-normal amount of androgens-a male sex hormone that most women have in small amounts. (
  • Many women with PCOS also develop non-cancerous cysts in their ovaries, although this isn't always the case. (
  • Blood tests to check hormone levels and an ultrasound to view images of the ovaries may be performed to confirm a PCOS diagnosis, along with an evaluation of symptoms such as skin changes and unusual hair growth. (
  • Learn about polycystic ovary syndrome (PCOS) and how this condition is treated at LVHN. (
  • Polycystic ovary syndrome (also called PCOS, Stein Leventhal syndrome, polycystic ovary disease or POD) is the most common hormonal and reproductive problem affecting women of childbearing age. (
  • In December 2021 , Rachael and Tom Sullivan found out they were pregnant with their first child, almost one year after Tom started posting about the foods he made to help his wife manage her polycystic ovary syndrome (PCOS). (
  • In secrecy, Tom Sullivan had started an Instagram account titled @mealssheeats, to document meals he was cooking as a holistic way to treat his wife's, Rachael Sullivan, polycystic ovary syndrome (PCOS). (
  • However, whether there is an additional risk among women with polycystic ovary syndrome (PCOS) is unknown. (
  • Your daughter has been diagnosed with a condition called polycystic ovary syndrome (PCOS) . (
  • Polycystic ovary syndrome, commonly known as PCOS, is a condition that affects an estimated 1 in 10 women worldwide. (
  • Polycystic ovary syndrome, or PCOS, is a common hormonal disorder affecting millions of women worldwide. (
  • Another essential tool for diagnosing PCOS is an ovarian biopsy, which involves taking a small tissue sample from one or both ovaries and looking at it under a microscope. (
  • If you have been diagnosed with polycystic ovary syndrome or PCOS, then it is likely that you will need to make some significant lifestyle changes to manage your symptoms effectively. (
  • October 13, 2011 - Women with polycystic ovary syndrome (PCOS) are at increased risk for pregnancy complications, whether or not they have undergone fertility treatments. (
  • A family member, friend, co-worker, or neighbor: You probably know someone with polycystic ovary syndrome (PCOS). (
  • Like the name sounds, PCOS is a disorder that is associated with multiple small cysts on the ovaries. (
  • Women with polycystic ovary syndrome (PCOS) often change their metabolic profile over time to decrease levels of androgens while often gaining a propensity for the development of the metabolic syndrome . (
  • We have developed the first international evidence-based guideline for the diagnosis and management of polycystic ovary syndrome (PCOS), with an integrated translation program incorporating resources for health professionals and consumers. (
  • Pelvic inflammatory disease (PID) is an infection that has spread to the uterus, ovaries or fallopian tubes. (
  • The bilateral uterine horns (of the uterus ) appear to terminate at each ovary via the oviduct . (
  • The finding, from a study published in the May issue of the journal Obstetrics & Gynecology, challenges conventional wisdom that removing ovaries along with the uterus offers the best chance for survival. (
  • Additionally, an ultrasound scan may evaluate other aspects of the reproductive system, such as uterine lining thickness and blood flow to the uterus and ovaries. (
  • The ovaries and uterus use hormones to communicate to each other about reproductive status. (
  • The uterus tells the ovaries when it is pregnant. (
  • As your bitch gets older, communication between the ovaries and uterus may not be as efficient as in her younger years. (
  • So as your bitch ages, even though she may not cycle as often as she did in her younger years, the ovaries and uterus continue a not-so-effective form of communication, which eventually can cause pyometra. (
  • Eviscerate my uterus and gouge out my ovaries. (
  • This image depicts a view of view of a uterus and ovary that had been excised, due to the presence of an ovarian abscess in a case of pelvic inflammatory disease (PID), which had been caused by an undisclosed anaerobic bacterium. (
  • Polycystic ovary syndrome is the most common cause of infertility due to absent ovulation. (
  • Each month, one follicle will mature into an egg, which is released from the ovary in a process known as ovulation . (
  • Ovulation is the process of an egg being released from the ovary and occurs on or around day 14 of the average menstrual cycle. (
  • First-line ovulation induction for polycystic ovary syndrome: an individual participant data meta-analysis. (
  • OHSS occurs only after ovulation, when the eggs are released from the ovary. (
  • The ovaries tell the uterine lining when to be ready for ovulation and when to go into estrus. (
  • The authors suggest that the effects of this high chemical dose do not arise due to the potency of its estrogenic activity, but rather through a direct effect on the ovary as sufficient exogenous gonadotropins were available to simulate ovulation. (
  • Your mucus is thick, white and dry before ovulation (when your ovary releases an egg). (
  • Polycystic ovary syndrome is a condition that affects women in their child-bearing years and alters the levels of multiple hormones, resulting in problems affecting many body systems. (
  • Most women with polycystic ovary syndrome produce excess male sex hormones (androgens), a condition called hyperandrogenism. (
  • In addition, the ovaries produce estrogen and progesterone, hormones essential to the female pig. (
  • The ovaries and fallopian tubes, however, may also undergo malignant transformation, and the hormones secreted by the ovary play a role in the etiology of certain types of cancers. (
  • One theory is that the hormones produced by the eggs inside these ovaries are responsible. (
  • Non-obese women with polycystic ovary syndrome, but without clinical or biochemical indications of insulin resistance, ovulate more frequently and experience relief from the overproduction of male hormones when taking insulin-sensitizing drugs, according to the study, which was conducted by scientists from three countries. (
  • Your ovaries also serve as your body's primary source of the hormones estrogen and progesterone. (
  • This decision involves a discussion of the risks and benefits of the loss of hormones from the ovaries. (
  • Surgical removal of both ovaries removes the hormones they make, which include estrogen, progesterone and testosterone. (
  • Estrogens are hormones made by a woman's ovaries. (
  • Other genes associated with polycystic ovary syndrome are involved in energy production, immune system responses to injury (inflammation), insulin production and regulation, and pathways involved in the production of fats. (
  • In polycystic ovary syndrome, one or both ovaries can contain multiple small, immature ovarian follicles that can appear as cysts on medical imaging. (
  • In polycystic ovary syndrome, abnormal hormone levels prevent follicles from growing and maturing to release egg cells. (
  • Instead, these immature follicles accumulate in the ovaries. (
  • Other genetic variants likely involved in a decrease in follicle-stimulating hormone are thought to contribute to the poor development of follicles in women with polycystic ovary syndrome. (
  • The ovary is small and lacking follicles and corpora lutea. (
  • Patients have high levels of the male hormone androgen, infrequent or prolonged menstrual periods, and follicles (small collections of fluid) in their ovaries. (
  • One of the mouse pups born to a female who was implanted with a 3-D printed ovary, which contained follicles tagged with green fluorescent protein. (
  • Cobalt Borate Neodecanoate Complex: In Vitro Mammalian Chromosome Aberration Test in Chinese Hamster Ovary Cells. (
  • Cobalt Naphthenate: In Vitro Mammalian Chromosome Aberration Test in Chinese Hamster Ovary Cells. (
  • H-26232: In Vitro Mammalian Chromosome Aberration Test in Chinese Hamster Ovary Cells. (
  • Ovarian remnant syndrome only occurs in women who have had their ovaries and fallopian tubes surgically removed. (
  • Angelina Jolie Had Ovaries & Fallopian Tubes REMOVED! (
  • After having a masectomy, Angelina Jolie makes another brave decision: deciding to have her ovaries and fallopian tubes removed. (
  • When atrophy is treatment related, it is important to describe the changes present in the ovary in the pathology narrative. (
  • Evidence indicates that high-grade serous ovarian carcinomas primarily arise from tissues that are not normally present in the ovary, and histogenetic pathways are informing risk-reduction strategies for the prevention of ovarian and ovary-associated cancers. (
  • Early surgical menopause is the removal of both ovaries before natural menopause and often accompanies a hysterectomy. (
  • The ovaries contain all the developing eggs the female pig will ever have. (
  • But when Mason killed all the eggs inside young ovaries before transplanting them into another set of older mice, he still saw the same benefits. (
  • Tests by researchers from the Rigshospitalet hospital in Copenhagen showed that a lab-made ovary can keep human eggs alive for weeks at a time, boosting hopes that it could be used in the future on women who have received treatments such as chemotherapy and radiotherapy. (
  • It affects the ovaries (the organs that store a woman's eggs), but can also affect the rest of the body. (
  • When she undergoes IVF, medications are often given to help the ovaries produce more eggs in a month than usual. (
  • For those that may want to have genetic children after removal of ovaries at the time of hysterectomy, it is possible to freeze eggs or embryos prior to surgery. (
  • This involves consultation with a fertility specialist and subsequent hormonal stimulation of the ovaries, with a minor surgical procedure to remove eggs from the body. (
  • Leaving ovaries in place can also allow for use of the eggs at a later time for fertility. (
  • Perimenopause is that stage where the ovaries begin to reduce releasing eggs and sometimes there is development of some of the early symptoms. (
  • Intended female parents who have premature ovarian failure (early menopause), whose ovaries have been removed, or who have a genetic concern about using their own eggs may consider using eggs that are donated by a woman without these conditions. (
  • Jeffrey Mason at Utah State University in Logan removed the ovaries of 10 mice that were 12 months old and had gone through oestropause, a transition similar to the human menopause. (
  • After menopause, our ovaries do shrink. (
  • Pre-menopause ovaries are 3-4cm, but after menopause they can be 0.5cm-1.0cm. (
  • Perimenopause and menopause is a normal natural life stage that is experienced by everyone with ovaries (or who has had ovaries). (
  • This medicine is also used to treat moderate to severe menopausal changes in and around your vagina and to treat certain conditions in women before menopause if their ovaries do not make enough estrogens naturally. (
  • Sometimes imaging with ultrasound, MRI or CT can have a hard time identifying ovaries for a multitude of reasons, with the most common being menopausal ovaries or lots of gas in the bowel, which can hide the ovaries. (
  • The follicle looks like a cyst on ultrasound and gives us the name polycystic ovaries. (
  • You may also have an ultrasound to look for cysts on your ovaries. (
  • This exam uses ultrasound waves to produce images of the internal reproductive organs to check for cysts on the ovaries. (
  • Typically, the recommendation is to leave normal appearing ovaries in place, even in gender affirming surgery, as they can be a backup source of hormone. (
  • Its primary feature is multiple cysts on the ovaries that lead to a cluster of symptoms including irregular menstrual cycles, acne, hirsutism (excess hair growth on the face and/or body), weight gain, and trouble sleeping. (
  • The symptoms of polycystic ovary symptom can vary significantly from woman to woman. (
  • Symptoms of small cell cancer of the ovary are often subtle. (
  • Pelvic symptoms may accompany enlarged ovary including: Abdominal, pelvic, or lower back pain that can be severe. (
  • These symptoms may be the sign of large ovarian cysts, ruptured cysts, or even a twisted ovary. (
  • The prevalence of polycystic ovary syndrome ranges from 4 percent to 21 percent, depending on the criteria used to make the diagnosis, but it is often reported to effect 6 to 10 percent of women worldwide. (
  • Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. (
  • The pathological diagnosis was borderline clear cell adenofibroma of the left ovary. (
  • Ovary - Atrophy is a suitable diagnosis for a short-term study. (
  • Population-based data on the prognosis of brain metastases at initial diagnosis of ovary cancer (OCBM) are currently lacking. (
  • Small Cell Cancer of the Ovary meets the criteria in 13.23 F with a diagnosis supported by biopsy. (
  • Reporting their overall results, the researchers write, "In the present population based study a diagnosis of polycystic ovary syndrome was associated with increased risks of adverse pregnancy outcomes that could not be attributed to the increased use of assisted reproductive technology or maternal characteristics such as advanced age or being overweight or obese. (
  • A diagnosis of leiomyosarcoma of ovary was made in a 60 year old female presenting with generalised weakness and abdominal lump. (
  • Genetic variations likely act in combination with health and lifestyle factors to influence a woman's overall risk of developing polycystic ovary syndrome. (
  • A woman's ovary may grow a cyst. (
  • An ovarian cyst is a fluid-filled sac that grows on a woman's ovary. (
  • Sometimes, in response to the ovarian stimulation necessary to encourage the ovaries to release more than one egg at a time, the woman's body reacts to the medications and to the process itself. (
  • A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. (
  • Future research would benefit from focusing on glucose control, medical treatment, and hormonal status among women with polycystic ovary syndrome during pregnancy. (
  • Ovaries continue to regulate hormonal releases, but as they age, they lose the efficiency to do it well. (
  • The pituitary also secretes endorphins (pronounced: en-DOR-fins), chemicals that act on the nervous system and reduce feelings of pain. (
  • Danish scientists have taken early steps towards creating an artificial human ovary designed to help women conceive after cancer treatments that can damage fertility. (
  • A three-centimeter uniloculated cyst with serous content was observed in the right ovary. (
  • Oligoanovulation with polycystic ovaries but not overt hyperandrogenism. (
  • Polycystic ovaries and associated clinical and biochemical features in young women. (
  • Should Ovaries Be Removed at the Time of Hysterectomy? (
  • It is an important question to consider whether the ovaries should be removed at the time of hysterectomy. (
  • This tissue can grow anywhere in the abdomen or pelvis, including on the ovary, and it behaves in the same way as it does during a menstrual cycle. (
  • For the first time in Germany, a woman has given birth to a child after removal and preservation of tissue from one of her ovaries. (
  • Women diagnosed with cancer are currently able to preserve their chances of conceiving by having an ovarian tissue transplant, where all or part of the ovary is removed and frozen before the fertility-harming treatments, ready to be used at a later date. (
  • The HJ1.Ov cell line was derived from the ovary tissue of a normal and healthy female Himalayan tahr ( Hemitragus jemlahicus ), which is a relative of the wild goat specially adapted to life in the rugged, mountainous environment of the Himalayas. (
  • During spays on older females, I have seen some ovaries look like a small piece of cauliflower with cysts and thickened tissue covering them. (
  • In more severe cases, the tissue lining may grow over the ovaries, creating cysts called endometriomas. (
  • Women who have their healthy ovaries removed when they have a hysterectomy face a higher risk of death, including death from coronary heart disease and lung cancer, than women who keep their ovaries, according to new research. (
  • Doctors have recommended for decades that women who get a hysterectomy consider having both ovaries removed-a surgical procedure called a bilateral oophorectomy-to prevent ovarian cancer later in life. (
  • Of the 600,000 women in the United States who get a hysterectomy every year, about 300,000 also have their ovaries removed-about 50 percent of those between the ages 40 and 44 and 78 percent of those between the ages of 45 and 64. (
  • I had a partial hysterectomy 18 years ago (my ovaries were not removed). (
  • Ovaries can be removed at the same time as hysterectomy, or they can be kept intact. (
  • About half of all women with polycystic ovary syndrome are overweight or have obesity and are at increased risk of a fatty liver. (
  • By age 40, about 10 percent of overweight women with polycystic ovary syndrome develop abnormally high blood sugar levels ( type 2 diabetes ), and up to 35 percent develop prediabetes (higher-than-normal blood sugar levels that do not reach the cutoff for diabetes). (
  • Women with polycystic ovary syndrome are also at increased risk for developing metabolic syndrome, which is a group of conditions that include high blood pressure ( hypertension ), increased belly fat, high levels of unhealthy fats and low levels of healthy fats in the blood, and high blood sugar levels. (
  • Women with polycystic ovary syndrome are more likely than women in the general popluation to have mood disorders such as depression . (
  • It is estimated that 20 to 40 percent of women with polycystic ovary syndrome have an affected mother or sister. (
  • Polycystic ovary syndrome , the most common endocrinopathy and most common cause of female infertility, affects 8%-13% of reproductive-aged women. (
  • While most women are not regularly aware of their ovaries, many women do experience pain or discomfort in that area from time to time. (
  • A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. (
  • Preliminary indication of a high prevalence of polycystic ovary syndrome in indigenous Australian women. (
  • Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome. (
  • Women with polycystic ovary disease have low levels of FSH and do not ovulate on a monthly basis. (
  • In the case of younger, reproductive-aged women, especially when the patient desires future fertility, the decision is easy: Unless their removal is absolutely indicated, the ovaries are typically retained. (
  • Could young ovaries provide anti-ageing benefits for older women, too? (
  • But it is difficult to detect and treat, so many women opt to have their ovaries taken out. (
  • Women can increase the chances of giving birth to a child later in their life by freezing some part of their ovaries, one of the world's leading gynecologists said. (
  • In women who are not overweight, it is thought that the ovaries make too much testosterone. (
  • Insulin-sensitizing drugs can help thin women with polycystic ovary syndrome even if they do not appear to be insulin resistant, broadening the range of women who can benefit from the therapy, a Virginia Commonwealth University researcher said in this month's issue of the journal Fertility and Sterility. (
  • This is significant because up to 30 percent of women with polycystic ovary syndrome are not overweight, and it has not been clear if such women would benefit from treatment with an insulin sensitizing drug for improving fertility," said John E. Nestler, M.D., chair of VCU's Division of Endocrinology and Metabolism, and lead author of the study. (
  • Polycystic ovary syndrome is the most common reproductive syndrome in women, affecting between 6 percent and 10 percent of those of childbearing age. (
  • Small cell cancer of the ovary tends to occur in young women (under 40 years of age). (
  • Malignant mixed M llerian tumor of the ovary is a rare and very aggressive neoplasm presenting most commonly in postmenopausal women and is composed of adenocarcinomatous and sarcomatous elements and, depending on the types of these elements, can be classified as homologous or heterologous. (
  • Many women experience pain in their ovaries from time to time, typically related to their menstrual cycle. (
  • In an editorial accompanying the article, Nick Macklon, MD, chair in obstetrics and gynecology at the University of Southampton, United Kingdom, writes, "It is clear that women with polycystic ovary syndrome should be considered 'high risk' obstetric patients, and that midwives, general practitioners, and obstetricians should monitor these women as such. (
  • Circulating miRNAs in Women with Polycystic Ovary Syndrome: A Longitudinal Cohort Study. (
  • Talc particles have been found in some normal ovaries, as in the core of primary cancers of the ovary, endometrium, and cervix of nonoccupationally talc or asbestos exposed women in Britain. (
  • 22(2): 239-245 patients with polycystic ovary syndrome is 3-7 times with altered overall praxis are considered dyspraxic greater than in regular women, also due to insulin and have learning disabilities or slight brain resistance1. (
  • According to the latest WHO data published in 2020 Ovary Cancer Deaths in Croatia reached 308 or 0.68% of total deaths. (
  • On its own, DMSO has been used by clinics in treating cancers of the bladder, ovary, breast and skin. (
  • Borderline clear cell tumor of the ovary is defined as a tumor that is composed of glands or cysts lined by bland cuboidal to flattened cells with clear or eosinophilic cytoplasm and atypia but without stromal invasion [ 1 ]. (
  • Primate ovaries are free of any such enclosure, presenting the risk that any protective agent applied to the ovary might escape and protect tumor cells as well. (
  • Distribution of Keratin Intermediate Filaments and Mitochondria in HJ1.Ov Cell Cultures - An adherent log phase culture of tahr ovary cells was treated for one hour with MitoTracker Red CMXRos in order to label the mitochondrial network, and the fixed cells were then incubated with mouse anti-cytokeratin primary antibodies followed by goat anti-mouse secondary antibodies (IgG) conjugated to Alexa Fluor 488. (
  • Proximity of the Golgi Complex and Nucleus in Normal Tahr Ovary Monolayer Cell Cultures - The close proximity between the Golgi complex and nuclei in HJ1.Ov cells was probed in a double immunofluorescence experiment with mouse anti-NPCP (nuclear pore complex protein) and rabbit anti-giantin primary antibodies. (
  • Metastatic ovarian cancer is an advanced stage malignancy that has spread from the cells in the ovaries to distant areas of the body. (
  • In Vitro Chromosome Aberration Test in Chinese Hamster Ovary (CHO-WBL) Cells. (
  • Small Cell Cancer of the Ovary is a highly aggressive tumor. (
  • Obesity and increased insulin levels (hyperinsulinemia) further increase the production of androgens in polycystic ovary syndrome. (
  • Polycystic ovary syndrome in Mexican-Americans: prevalence and association with the severity of insulin resistance. (
  • As a result, the increased level of insulin causes more testosterone to be released from the ovaries. (
  • Hypertension was diagnosed insulin resistance, such as acanthosis nigri- when the average systolic and/or diastolic cans or polycystic ovary disease (PCOD). (
  • A pathology report of a biopsy specimen from the ovary showing small cell cancer. (
  • The prevalence and features of the polycystic ovary syndrome in an unselected population. (
  • The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. (
  • The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. (
  • This is when your ovary releases a mature egg, usually right in the middle of your menstrual cycle. (
  • According to the 2014 World Health Organization classification system, epithelial tumors of the ovary can be classified into three categories: benign, borderline, and malignant [ 1 ]. (
  • Most clear cell tumors of the ovary are malignant. (
  • Though the risk of ovarian and breast cancer declined after ovary removal, women's risk of heart disease and stroke nearly doubled and risk of death overall rose by 40 percent. (
  • Xi S, Li Z, Guo Q, Lin W, Liang X, Ma L. Prognostic Factors among Brain Metastases in Newly Diagnosed Ovary Cancer: A Large Real-world Study. (
  • This study provided a population-based estimate of the proportion and prognosis for newly diagnosed ovary cancer with brain metastases. (
  • Small Cell Cancer of the Ovary is an extremely rare type of ovarian cancer that is distinguished from other ovarian epithelial and ovarian germ cell tumors. (
  • There is no standard or routine screening test for small cell cancer of the ovary. (
  • The primary form of treatment for Small Cell Cancer of the Ovary is surgery with chemotherapy or radiotherapy, depending on the stage of the disease. (
  • It can lead to deafness, swelling of the brain and/or spinal cord covering, painful swelling of the testicles or ovaries, and, very rarely, death. (
  • The ovaries serve an important endocrine function, and their proper activity during the reproductive years is associated with long-term health benefits. (
  • In their case, the ovary no longer serves a reproductive function and its activity as an endocrine organ is minimal. (
  • The endocrine (pronounced: EN-duh-krin) system influences almost every cell, organ, and function of our bodies. (
  • Since then we have brought the concept of protecting the ovaries from damage caused by anticancer treatments all the way from an idea on paper, through a decade of mouse studies, to a proof of concept in living primates. (
  • Surgical resection reveals a firm mass with a white-yellow bosselated outer surface measuring 8.0 cm in greatest dimension, located on the upper pole of an otherwise grossly unremarkable ovary. (
  • Oophorectomy is surgical removal of one or both ovaries. (
  • Hypogonadism refers to a condition in which little or no hormone is produced by the testes or ovaries. (
  • Histologically borderline tumors of the ovary are noninvasive epithelial tumors that show greater epithelial proliferation and cytologic atypia than benign tumors. (
  • Herein, we present a case of borderline clear cell adenofibroma of the ovary in a 58-year-old woman who presented with a pelvic mass and constipation. (
  • Herein, we present a rare case of borderline clear cell adenofibroma of the ovary presented with a pelvic mass and constipation. (
  • Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. (
  • Polycystic ovary syndrome is a complex disorder that isn't fully understood. (
  • The ovaries are two small glands situated on either side of the lower pelvis. (
  • Normal ovaries are about the size and consistence of a soybean in small dogs and a lima bean in large dogs. (
  • The majority of borderline tumors of the ovary are serous tumors, followed by mucinous tumors [ 2 ]. (