Ovarian Neoplasms
Cystadenoma
Brenner Tumor
A smooth, solid or cystic fibroepithelial (FIBROEPITHELIAL NEOPLASMS) tumor, usually found in the OVARIES but can also be found in the adnexal region and the KIDNEYS. It consists of a fibrous stroma with nests of epithelial cells that sometimes resemble the transitional cells lining the urinary bladder. Brenner tumors generally are benign and asymptomatic. Malignant Brenner tumors have been reported.
Granulosa Cell Tumor
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Sertoli-Leydig Cell Tumor
A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.
Thecoma
A gonadal stromal neoplasm composed only of THECA CELLS, occurring mostly in the postmenopausal OVARY. It is filled with lipid-containing spindle cells and produces ESTROGENS that can lead to ENDOMETRIAL HYPERPLASIA; UTERINE HEMORRHAGE; or other malignancies in postmenopausal women and sexual precocity in girls. When tumors containing theca cells also contain FIBROBLASTS, they are identified as thecoma-fibroma tumors with less active hormone production.
Cystadenocarcinoma
A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)
Dysgerminoma
A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
Sertoli Cell Tumor
Dermoid Cyst
Sex Cord-Gonadal Stromal Tumors
Neoplasms derived from the primitive sex cord or gonadal stromal cells of the embryonic GONADS. They are classified by their presumed histogenesis and differentiation. From the sex cord, there are SERTOLI CELL TUMOR and GRANULOSA CELL TUMOR; from the gonadal stroma, LEYDIG CELL TUMOR and THECOMA. These tumors may be identified in either the OVARY or the TESTIS.
Cystadenoma, Serous
A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972)
Teratoma
A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
Carcinoma
Neoplasm Staging
Immunohistochemistry
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Neoplasms
Neoplasms, Cystic, Mucinous, and Serous
Neoplasms, Multiple Primary
Neoplasms, Second Primary
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Adenocarcinoma, Mucinous
Myeloproliferative Disorders
Neoplasms, Connective and Soft Tissue
Neoplasms, Plasma Cell
Cystadenoma, Mucinous
Gastrointestinal Neoplasms
Carcinoma, Pancreatic Ductal
Neoplasms, Experimental
Neoplasms, Vascular Tissue
Neoplasms, Radiation-Induced
Adenocarcinoma, Papillary
Carcinoma, Papillary
Testicular Neoplasms
Neoplasms, Muscle Tissue
Neoplasms, Glandular and Epithelial
Cystadenocarcinoma, Mucinous
A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)
Soft Tissue Neoplasms
Hematologic Neoplasms
Neoplasm Proteins
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Neoplasms, Adnexal and Skin Appendage
Vascular Neoplasms
Palatal Neoplasms
Antigens, Neoplasm
An improved method for the structural profiling of keratan sulfates: analysis of keratan sulfates from brain and ovarian tumors. (1/9962)
A previously developed method for the structural fingerprinting of keratan sulfates (Brown et al., Glycobiology, 5, 311-317, 1995) has been adapted for use with oligosaccharides fluorescently labeled with 2-aminobenzoic acid following keratanase II digestion. The oligosaccharides are separated by high-pH anion-exchange chromatography on a Dionex AS4A-SC column. This methodology permits quantitative analysis of labeled oligosaccharides which can be detected at the sub-nanogram ( approximately 100 fmol) level. Satisfactory calibration of this method can be achieved using commercial keratan sulfate standards. Keratan sulfates from porcine brain phosphocan and human ovarian tumors have been examined using this methodology, and their structural features are discussed. (+info)Role of dexamethasone dosage in combination with 5-HT3 antagonists for prophylaxis of acute chemotherapy-induced nausea and vomiting. (2/9962)
Dexamethasone (20 mg) or its equivalent in combination with 5-HT3 antagonists appears to be the gold-standard dose for antiemetic prophylaxis. Additional to concerns about the use of corticosteroids with respect to enhanced tumour growth or impaired killing of the tumour cells, there is evidence that high-dosage dexamethasone impairs the control of delayed nausea and emesis, whereas lower doses appear more beneficial. To come closer to the most adequate dose, we started a prospective, single-blind, randomized trial investigating additional dosage of 8 or 20 mg dexamethasone to tropisetron (Navoban), a 5-HT3 receptor antagonist, in cis-platinum-containing chemotherapy. After an interim analysis of 121 courses of chemotherapy in 69 patients, we have been unable to detect major differences between both treatment alternatives. High-dose dexamethasone (20 mg) had no advantage over medium-dose dexamethasone with respect to objective and subjective parameters of acute and delayed nausea and vomiting. In relation to concerns about the use of corticosteroids in non-haematological cancer chemotherapy, we suggest that 8 mg or its equivalent should be used in combination with 5-HT3 antagonists until further research proves otherwise. (+info)Cancer risk in close relatives of women with early-onset breast cancer--a population-based incidence study. (3/9962)
Inherited susceptibility to breast cancer is associated with an early onset and bilateral disease. The extent of familial risks has not, however, been fully assessed in population-based incidence studies. The purpose of the study was to quantify the risks for cancers of the breast, ovary and other sites of close relatives of women in whom breast cancer was diagnosed at an early age. Records collected between 1943 and 1990 at the Danish Cancer Registry were searched, and 2860 women were found in whom breast cancer was diagnosed before age 40. Population registers and parish records were used to identify 14 973 parents, siblings and offspring of these women. Cancer occurrence through to 31 December 1993 was determined within the Cancer Registry's files and compared with national incidence rates. Women with early-onset breast cancer were at a nearly fourfold increased risk of developing a new cancer later in life (268 observed vs. 68.9 expected). The excess risk was most evident for second cancer of the breast (181 vs. 24.5) and for ovarian cancer (20 vs. 3.3). For mothers and sisters, risks for cancers of the breast and ovary were significantly increased by two- to threefold. Bilateral breast cancer and breast-ovarian cancer were very strong predictors of familial risks, with one in four female relatives predicted to develop breast and/or ovarian cancer by age 75. Mothers had a slightly increased risk of colon cancer, but not endometrial cancer. The risk for breast cancer was also increased among fathers (standardized incidence ratio 2.5; 95% CI 0.5-7.4) and especially brothers (29; 7.7-74), although based on small numbers. The risk for prostatic cancer was unremarkable. In this large population-based survey, the first-degree relatives of women who developed breast cancer before age 40 were prone to ovarian cancer as well as male and female breast cancer, but not other tumours that may share susceptibility genes with breast cancer. (+info)Frequent silencing of the GPC3 gene in ovarian cancer cell lines. (4/9962)
GPC3 encodes a glypican integral membrane protein and is mutated in the Simpson-Golabi-Behmel syndrome. Simpson-Golabi-Behmel syndrome, an X-linked condition, is characterized by pre- and postnatal overgrowth as well as by various other abnormalities, including increased risk of embryonal tumors. The GPC3 gene is located at Xq26, a region frequently deleted in advanced ovarian cancers. To determine whether GPC3 is a tumor suppressor in ovarian neoplasia, we studied its expression and mutational status in 13 ovarian cancer cell lines. No mutations were found in GPC3, but its expression was lost in four (31%) of the cell lines analyzed. In an of the cases where GPC3 expression was lost, the GPC3 promoter was hypermethylated, as demonstrated by Southern analysis. Expression of GPC3 was restored by treatment of the cells with the demethylating agent 5-aza-2'-deoxycytidine. A colony-forming assay confirmed that ectopic GPC3 expression inhibited the growth of ovarian cancer cell lines. Our results show that GPC3, a gene involved in the control of organ growth, is frequently inactivated in a subset of ovarian cancers and suggest that it may function as a tumor suppressor in the ovary. (+info)Survival in familial, BRCA1-associated, and BRCA2-associated epithelial ovarian cancer. United Kingdom Coordinating Committee for Cancer Research (UKCCCR) Familial Ovarian Cancer Study Group. (5/9962)
The natural history of hereditary and BRCA1- and BRCA2-associated epithelial ovarian cancer may differ from that of sporadic disease. The purpose of this study was to compare the clinical characteristics of BRCA1- and BRCA2-associated hereditary ovarian cancer, hereditary ovarian cancer with no identified BRCA1/2 mutation, and ovarian cancer in population-based controls. BRCA1 and BRCA2 mutation testing was carried out on index cases from 119 families with site-specific epithelial ovarian cancer or breast-ovarian cancer. We estimated overall survival in 151 patients from 57 BRCA1 and BRCA2 mutation families and compared it with that in 119 patients from 62 families in which a BRCA1/2 mutation was not identified. We compared clinical outcome and data on tumor histopathology, grade, and stage. We also compared survival in familial epithelial ovarian cancer, whether or not a mutation was identified, with that of an age-matched set of population control cases. Overall survival at 5 years was 21% (95% confidence interval, 14-28) in cases from BRCA1 mutation families, 25% (8-42) in BRCA2 mutation families, and 19% (12-26) in families with no identified mutation (P = 0.91). Survival in familial ovarian cancer cases as a whole was significantly worse than for population controls (P = 0.005). In the familial cases, we found no differences in histopathological type, grade, or stage according to mutation status. Compared to population control cases, mucinous tumors occurred less frequently in the familial cases (2 versus 12%, P<0.001), and a greater proportion of the familial cases presented with advanced disease (83% stage III/IV versus 56%; P = 0.001). We have shown that survival in familial ovarian cancer cases is worse than that in sporadic cases, whether or not a BRCA1/2 mutation was identified, perhaps reflecting a difference in biology analogous to that observed in breast cancer. (+info)Survival after breast cancer in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers. (6/9962)
BACKGROUND: Studies of survival following breast and ovarian cancers in BRCA1 and/or BRCA2 mutation carriers have yielded conflicting results. We undertook an analysis of a community-based study of Ashkenazi Jews to investigate the effect of three founder mutations in BRCA1 and BRCA2 on survival among patients with breast or ovarian cancer. METHODS: We collected blood samples and questionnaire data from 5318 Ashkenazi Jewish volunteers. The blood samples were tested for 185delAG (two nucleotide deletion) and 5382insC (single nucleotide insertion) mutations in BRCA1 and the 6174delT (single nucleotide deletion) mutation in BRCA2. To estimate survival differences in the affected relatives according to their BRCA1 and/or BRCA2 mutation carrier status, we devised and applied a novel extension of the kin-cohort method. RESULTS: Fifty mutation carriers reported that 58 of their first-degree relatives had been diagnosed with breast cancer and 10 with ovarian cancer; 907 noncarriers reported 979 first-degree relatives with breast cancer and 116 with ovarian cancer. Kaplan-Meier estimates of median survival after breast cancer were 16 years (95% confidence interval [CI] = 11-40) in the relatives of carriers and 18 years (95% CI = 15-22) in the relatives of noncarriers, a difference that was not statistically significant (two-sided P = .87). There was also no difference in survival times among the 126 first-degree relatives with ovarian cancer. We found no survival difference between patients with breast or ovarian cancer who were inferred carriers of BRCA1 and/or BRCA2 mutations and noncarriers. CONCLUSIONS: Carriers of BRCA1 and BRCA2 mutations appeared to have neither better nor worse survival prognosis. (+info)In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector. (7/9962)
Adenoviral vectors, encoding genes for cell surface antigens or receptors, have been used to induce their high level expression on tumor cells in vitro and in vivo. These induced antigens and receptors can then be targeted with radiolabeled antibodies or peptides for potential radiotherapeutic applications. The purpose of this study was to determine a dosing schema of an adenoviral vector encoding the human somatostatin receptor subtype 2 (AdCMVhSSTr2) for achieving the highest tumor localization of [(111)In]-DTPA-D-Phe1-octreotide, which binds to this receptor, in a human ovarian cancer model as a prelude to future therapy studies. AdCMVhSSTr2 was produced and used to induce hSSTr2 on A427 human nonsmall cell lung cancer cells and on SKOV3.ipl human ovarian cancer cells in vitro, as demonstrated by competitive binding assays using [125I]-Tyr1-somatostatin and [(111)In]-DTPA-D-Phe1-octreotide. Mice bearing i.p. SKOV3.ip1 tumors administered 1 x 10(9) plaque-forming units of AdCMVhSSTr2 i.p. 5 days after tumor cell inoculation, followed by an i.p. injection of [(111)In]-DTPA-D-Phe1-octreotide 2 days later, showed a range of 15.3-60.4% median injected dose/gram (ID/g) in tumor at 4 h after injection compared with 3.5% ID/g when [125I]-Tyr1-somatostatin was administered and 0.3% ID/g when the negative control peptide [125I]-mIP-bombesin was administered. Mice administered a control adenoviral vector encoding the gastrin-releasing peptide receptor did not have tumor localization of [(111)In]-DTPA-D-Phe1-octreotide (<1.6% ID/g), demonstrating specificity of [(111)In]-DTPA-D-Phe1-octreotide for the AdCMVhSSTr2 induced tumor cells. In another set of experiments, the tumor localization of [(111)In]-DTPA-D-Phe1-octreotide was not different 1, 2, or 4 days after AdCMVhSSTr2 injection (31.8, 37.7, and 40.7% ID/g, respectively; P = 0.88), indicating that multiple injections of radiolabeled peptide can be administered with equivalent uptake over a 4-day period. [(111)In]-DTPA-D-Phe1-octreotide tumor localization in animals administered AdCMVhSSTr2 on consecutive days or 2 days apart was 22.4% ID/g and 53.2% ID/g, respectively (P = 0.009) when [(111)In]-DTPA-D-Phe1-octreotide was given 1 day after the second AdCMVhSSTr2 injection. There was no difference in [(111)In]-DTPA-D-Phe1-octreotide localization after a single AdCMVhSSTr2 injection (40.7% ID/g) or two injections of AdCMVhSSTr2 given 1 (45.9% ID/g) or 2 (53.2% ID/g) days apart, where [(111)In]-DTPA-D-Phe1-octreotide was given in each case 4 days after the first AdCMVhSSTr2 injection (P = 0.65). Therefore, two AdCMVhSSTr2 injections did not increase [(111)In]-DTPA-D-Phe1-octreotide tumor localization compared with one injection, which eliminates concerns about an immune response to a second dose of AdCMVhSSTr2. This will be the basis for a therapeutic protocol with multiple administrations of an octreotide analogue labeled with a therapeutic radioisotope. (+info)Combination of theanine with doxorubicin inhibits hepatic metastasis of M5076 ovarian sarcoma. (8/9962)
Theanine is a peculiar amino acid existing in green tea leaves, which was previously indicated to enhance the antitumor activity of doxorubicin. In the present study, the effect of combination of theanine with doxorubicin against hepatic metastasis of M5076 ovarian sarcoma was investigated. The primary tumor was significantly reduced by the combined treatment on M5076 transplanted (s.c.) mice. The liver weight of control mice increased to twice the normal level because of hepatic metastasis of M5076. In contrast, the injection of doxorubicin alone or theanine plus doxorubicin suppressed the increase in liver weight and inhibited hepatic metastasis. Moreover, the liver weights and metastasis scores demonstrated that theanine enhanced the inhibition of hepatic metastasis induced by doxorubicin. Furthermore, in vitro experiments indicated that theanine increased the intracellular concentration of doxorubicin remaining in M5076 cells. This action suggests that theanine leads the enhancement of the suppressive efficacy of doxorubicin on hepatic metastasis in vivo. Therefore, it was proved that theanine increased not only the antitumor activity on primary tumor but also the metastasis-suppressive efficacy of doxorubicin. The effect of theanine on the efficacy of antitumor agents is expected to be applicable in clinical cancer chemotherapy. (+info)Race/ethnic variations in ovarian cancer mortality in the United States, 1992-1997<...
Aberrant non-canonical WNT pathway as key-driver of high-grade serous ovarian cancer development<...
Ovarian Cancer Treatment Cost in Kolkata, Ovarian Cancer Treatment Hospitals | Credihealth
Adenosine triphosphate-based chemotherapy response assay predicts long-Term survival of primary epithelial ovarian cancer<...
While ovarian cancer remains the most lethal gynecological malignancy in the | EGFR Tyrosine Kinase Inhibitors Activate...
Olaparib (PARP inhibitors) - Ovarian Cancer Treatment
Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization...
Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: A report from the ovarian cancer...
Therapeutic Targeting of ATP7B in Ovarian Carcinoma | Clinical Cancer Research
Mass spectrometry-based peptidome profiling of human serous ovarian cancer tissues | Bioinformatics Solutions Inc.
Analysis of resistance of primary ovarian cancer cells to viral oncolysis
Transformation of human ovarian surface epithelial cells by Kruppel-li
Response to microtubule-interacting agents in primary epithelial ovarian cancer cells - pdf descargar
Combination Chemotherapy Plus IM-862 in Treating Patients With Resected Stage III Ovarian Cancer or Primary Peritoneal Cancer -...
DNA Repair Pathway Score For Predicting Chemotherapy Response In Ovarian Cancer Patients - Redorbit
Comparison of ERCC1/XPF genetic variation, mRNA and protein levels in women with advanced stage ovarian cancer treated with...
AXL is an essential factor and therapeutic target for metastatic ovarian cancer. - Department of Oncology
Expression of estrogen-responsive finger protein (Efp) is associated with advanced disease in human epithelial ovarian cancer<...
A single nucleotide polymorphism in catalase is strongly associated with ovarian cancer survival<...
NewsCap: Younger women with early-stage ovarian cancer can keep the healthy ovary and uterus | Article | NursingCenter
Ovarian Cancer Treatment | MD Anderson Cancer Center
Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis...
Functional polymorphisms in FOXC2 gene and Epithelial ovarian Cancer susceptibility in Chinese population | Journal of Ovarian...
The role of estrogen in the survival of ovarian tumors-A study of the human ovarian adenocarcinoma cell lines OC-117-VGH and...
Background Glycogen synthase kinase-3 (GSK-3) is a multifunctional serine/threonine kinase that - Novel therapeutic agents in...
Ovarian Cancer treatments. Survival, toxicity, side effects. Chemotherapy. New York, NY, United States
Ovarian Cancer treatments. Survival, toxicity, side effects. Chemotherapy. New York, United States
Ovarian cancer
Impact of XRCC1 Arg399Gln polymorphism on ovarian cancer risk in Serbian women | OncologyPRO
Ovarian Cancer - Treatment Options - Minnesota Oncology
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Pathology of stage I versus stage III ovarian carcinoma with implications for pathogenesis and screening<...
Borderline ovarian tumors in Sweden 1960-2005 : trends in incidence and age at diagnosis compared to ovarian cancer
Metastatic Ovarian Cancer, Pipeline Review, H2 2015
Role of CSF-1 in progression of epithelial ovarian cancer<...
Ovarian Cancer Development and Metastasis - ScienceOpen
Laparoscopic approach in early-stage ovarian cancer promising
Correlation of p53 immunostaining in primary and residual ovarian cancer at the time of positive second-look laparotomy and its...
PARP Inhibitors in Epithelial Ovarian Cancer | Bentham Science
Ovarian cancer detection by DNA methylation in cervical scrapings<...
MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for...
CAISMOV24, a new human low-grade serous ovarian carcinoma cell line | BMC Cancer | Full Text
Stage Three Ovarian Cancer Survival Rate
PPAR{gamma} ligands induce growth inhibition and apoptosis through p63 and p73 in human ovarian cancer cells (Journal Article) ...
Low concentrations of bisphenol A promote human ovarian cancer cell proliferation and glycolysis-based metabolism through the...
Ovarian Epithelial Cancer Treatment,Ovarian Epithelial Treatment India
Artificial intelligence weights the importance of factors predicting complete cytoreduction at secondary cytoreductive surgery...
Methiothepin suppresses human ovarian cancer cell growth by repressing mitochondrion-mediated metabolism and inhibiting...
Mucinous epithelial ovarian cancers are clinically and morphologically distinct through the - MEK Inhibitors Reverse cAMP...
GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma.
Quantitative analysis of follicle-stimulating hormone receptor in ovarian epithelial tumors: A novel approach to explain the...
Novel mechanism of reduced proliferation in ovarian clear cell carcinoma cells: Cytoplasmic sequestration of CDK2 by p27<...
Endometrial cancers in mutation carriers from hereditary breast ovarian cancer syndrome kindreds<...
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Suppression of ascites formation and re-accumulation associated with human ovarian cancer by an anti-VPF monoclonal antibody in...
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Evaluation of the cytotoxicity of the Bithionol - cisplatin combination in a panel of human ovarian cancer cell lines | BMC...
The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancer. - Oxford Clinical Trials...
Correlation of p53 immunostaining in primary and residual ovarian cancer at the time of positive second-look laparotomy and its...
Tumor associated mesenchymal stem cells protect ovarian cancer cells from hyperthermia through CXCL12 | QScience.com
Gefitinib in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium<...
Ovarian cancer risk factors by tumor aggressiveness: An analysis from the Ovarian Cancer Cohort Consortium<...
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Teratoma
Ovarian Neoplasm Imaging. Springer Science & Business Media. p. 165. ISBN 9781461486336. "NCI Dictionary of Cancer Terms". ... Ovarian teratomas represent about a quarter of ovarian tumors and are typically noticed during middle age. Testicular teratomas ... Treatment of coccyx, testicular, and ovarian teratomas is generally by surgery. Testicular and immature ovarian teratomas are ... Ovarian teratomas often present with abdominal or pelvic pain, caused by torsion of the ovary or irritation of its ligaments. A ...
Ovarian serous cystadenoma
... is the most common ovarian neoplasm, representing 20% of ovarian neoplasms, and is benign. It has a very superficial ... "Common Causes of Ovarian Enlargement: Ovarian neoplasms". Human Reproduction. University of Utah Medpath. Cheng EJ, Kurman RJ, ... resembling ovarian surface epithelium Ovarian serous cystadenoma accounts for the largest proportion of benign ovarian tumours ... Serous ovarian cystadenocarcinomas account for ~25% of serous tumours. Ovarian cancer Pancreatic serous cystadenoma Serous ...
Ovarian fibroma
The ovarian fibroma, also fibroma, is a benign sex cord-stromal tumour. Ovarian fibromas represent 4% of all ovarian neoplasms ... There may be thecomatous areas (fibrothecoma). The presence of an ovarian fibroma can cause ovarian torsion in some cases. ... Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal". Journal of ... Diagnosis is usually made by ultrasonography showing a solid ovarian lesion, or, on some occasions, mixed tumors with solid and ...
Leydig cell tumour
Sachdeva P, Arora R, Dubey C, Sukhija A, Daga M, Singh DK (April 2008). "Sertoli-Leydig cell tumor: a rare ovarian neoplasm. ... Animal studies a suggest possible link with C8 (C8HF15O2, perfluorooctanoic acid). Presence of an ovarian tumour plus hormonal ... is a member of the sex cord-stromal tumour group of ovarian and testicular cancers. It arises from Leydig cells. While the ... Ovarian cancer, Male genital neoplasia, Rare cancers, Endocrine neoplasia, Endocrine-related cutaneous conditions). ...
Ovarian cystadenoma
v t e (Ovarian cancer, All stub articles, Neoplasm stubs). ... Ovarian cystadenoma is a cystic benign tumor of the ovary. Two ... Limaiem, Faten; Mlika, Mouna (2019). "Ovarian Cystadenoma". StatPearls. StatPearls Publishing. Retrieved 21 November 2019. ...
Adnexal mass
Relative frequency of primary ovarian neoplasms: a 10-year review. Obstet Gynecol 1989; 74:921. Magrina JF, Espada M, Munoz R, ... In premenopausal women, adnexal masses include ovarian cysts, ectopic (tubal) pregnancies, benign (noncancerous) or malignant ( ... cancerous) tumors, endometriomas, polycystic ovaries, and tubo-ovarian abscess. The most common causes for adnexal masses in ...
Ovarian tumor
... s, or ovarian neoplasms, are tumors arising from the ovary. They can be benign or malignant (ovarian cancer). They ... Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many ... Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors in a referral hospital in Nepal". Journal of ... Unless otherwise specified in boxes, reference is: Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014). "Spectrum of ovarian tumors ...
Lithopedion
"Old abdominal pregnancy presenting as an ovarian neoplasm". Journal of Korean Medical Science. 17 (2): 274-75. doi:10.3346/jkms ... Lithopedia can originate both as tubal and ovarian pregnancies, although tubal pregnancy cases are more common. * After death ... following the rupture of the placental and ovarian membranes; and Lithokelyphopedion ("Stone Sheath [and] Child"), where both ...
Sertoli-Leydig cell tumour
A rare ovarian neoplasm. Case report and review of literature". Gynecological Endocrinology. 24 (4): 230-4. doi:10.1080/ ... is a testosterone-secreting ovarian tumor and is a member of the sex cord-stromal tumour group of ovarian and testicular ... Presence of an ovarian tumour plus hormonal disturbances suggests a Sertoli-Leydig cell tumour. However, hormonal disturbance ... "DICER1 Mutations in Familial Multinodular Goiter With and Without Ovarian Sertoli-Leydig Cell Tumors". JAMA. 305 (1): 68-77. ...
Fibroma
It appears in the sex cord-stromal tumour group of ovarian neoplasms. Ovary fibromas are most frequent during middle age, and ... There may be thecomatous areas (fibrothecoma). The presence of an ovarian fibroma can cause ovarian torsion in some cases. ...
Thecoma
... s or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified ... October 2004). "Ovarian thecoma associated in the first trimester of pregnancy". J. Obstet. Gynaecol. Res. 30 (5): 368-71. doi: ... Grossly and microscopically, it consists of the ovarian cortex. Microscopically, the tumour cells have abundant lipid-filled ...
Fatty acid synthase
... in ovarian neoplasms predicts shorter survival". Human Pathology. 28 (6): 686-692. doi:10.1016/S0046-8177(97)90177-5. PMID ...
Pancreatic mucinous cystic neoplasm
"Pancreatic mucinous cystic neoplasm defined by ovarian stroma: demographics, clinical features, and prevalence of cancer". ... Pancreatic mucinous cystic neoplasm (MCN) is a type of cystic lesion that occurs in the pancreas. Amongst individuals ... Intraductal papillary mucinous neoplasm Pancreatic serous cystadenoma Elta, GH; Enestvedt, BK; Sauer, BG; Lennon, AM (April ... Histologic evaluation of MCNs shows mucin-producing columnar epithelial lining, which is surrounded by ovarian-like stroma. ...
MAGEA4
"Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens in serous ovarian neoplasms". Clinical Cancer Research. 9 (17): ...
Guanylate cyclase 2C
2009). "Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms". ...
Brenner tumour
Brenner tumors are an uncommon subtype of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority are ... Histologically, Leydig cell tumors of the testes and ovarian stromal Leydig cell tumors (ovarian hyperandrogenism and ... Histology at University of Utah (Articles with short description, Short description is different from Wikidata, Ovarian cancer) ... the ovarian granulosa cell tumor, with the fluid-filled spaces Call-Exner bodies between the granulosa cells. Transitional cell ...
Surface epithelial-stromal tumor
... s are a class of ovarian neoplasms that may be benign or malignant. Neoplasms in this group are ... One rare but noteworthy condition associated with mucinous ovarian neoplasms is pseudomyxoma peritonei. As primary ovarian ... For more general information, see ovarian cancer. Research suggests that in the first line treatment of Endometrial Ovarian ... of all ovarian neoplasms In some cases mucinous tumors are characterized by more cysts of variable size and a rarity of surface ...
Sertoli cell
Sertoli-Leydig cell tumour is part of the sex cord-stromal tumour group of ovarian neoplasms. These tumors produce both Sertoli ...
Gonadoblastoma
Laparoscopy may be an option if the surgeon is particularly skilled in removing ovarian neoplasms via laparoscopy intact. If ... A gonadoblastoma is a complex neoplasm composed of a mixture of gonadal elements, such as large primordial germ cells, immature ...
Signet ring cell
"A case of ovarian metastasis of gallbladder carcinoma simulating primary ovarian neoplasm: diagnostic pitfalls and review of ... ovarian stroma and testis. The NCI Thesaurus identifies the following types of signet ring cell Castration cell, a non- ...
Krukenberg tumor
Immunohistochemistry may help in diagnosing Krukenberg tumors from primary ovarian neoplasms but needs to be applied with ... In most countries, cancer that has metastasized to the ovary accounts for only about 1 to 2% of ovarian cancer; in the ... Krukenberg tumors can occasionally provoke a reaction of the ovarian stroma which leads to hormone production, that results in ... Papakonstantinou E, Liapis A, Kairi-Vassilatou E, Iavazzo C, Kleanthis CK, Kondi-Pafiti A (2011). "Virilizing ovarian ...
Endometrioid tumor
They are part of the surface epithelial tumor group of ovarian neoplasms (10-20% of which are the endometrioid type). Benign ... Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN gene mutation profiles. PTEN mutations are more ... "Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles". Modern Pathology. 27 (1): 128 ... CTNNB1 mutations are significantly different in low-grade ovarian endometrioid carcinomas (53%) compared with low-grade ...
Eosinophilia
Of solid tumor neoplasms, ovarian cancer is most likely to provoke eosinophilia, though any other cancer can cause the ... The World Health Organization classifies these disorders into a) Myeloid and lymphoid neoplasms with eosinophilia and ... Reiter A, Gotlib J (2017). "Myeloid neoplasms with eosinophilia". Blood. 129 (6): 704-714. doi:10.1182/blood-2016-10-695973. ...
Chlorambucil
... trophoblastic neoplasms, and ovarian carcinoma. Moreover, it also has been used as an immunosuppressive drug for various ...
Dactinomycin
This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ... ovarian cancer. It is given by injection into a vein. Most people develop side effects. Common side effects include bone marrow ...
Mesothelial hyperplasia
... ovarian neoplasms (malignant or benign), and peritoneal effusions. Atypical mesothelial hyperplasia Herbert, Ronald A.; ... Peritoneal mesothelial hyperplasia can be encountered in inflammatory pelvic disease with tubo-ovarian abscess, ...
Ovarian mucinous tumor
Mucinous tumors are part of the surface epithelial-stromal tumor group of ovarian neoplasms, and account for approximately 36% ... Ovarian Cancer. In: Pharmacotherapy: A pathophysiologic approach.8th ed. Dipiro JT, Talbert RL, Yee GC et al., New York: McGraw ... It is well documented that malignancy may be only focally present in mucinous neoplasms of the ovary, so thorough sampling is ... Pseudomyxoma peritonei may present as a result of an ovarian mucinous tumor, however this is a rare cause of this condition, ...
Pancreatic serous cystadenoma
Ovarian serous cystadenoma Pancreatic mucinous cystadenoma Solid pseudopapillary neoplasm Jais B, Rebours V, Malleo G, Salvia R ... mixed serous-endocrine neoplasm, and VHL-associated serous cystic neoplasm. This latter classification scheme is useful because ... Serous cystic neoplasms that have spread ("metastasized") to another organ are considered malignant and are designated "serous ... In contrast to some of the other cyst-forming tumors of the pancreas (such as the intraductal papillary mucinous neoplasm and ...
Ovarian cancer
They can develop further into a variety of other neoplasms, including choriocarcinoma, yolk sac tumor, and teratoma. They occur ... Clear cell ovarian carcinoma is a rare subtype of epithelial ovarian cancer. Those diagnosed with clear cell ovarian carcinoma ... of hereditary epithelial ovarian cancer. Serous ovarian cancer is the most common type of epithelial ovarian cancer and it ... The Risk of Ovarian Malignancy algorithm uses CA-125 levels and HE4 levels to calculate the risk of ovarian cancer; it may be ...
Neoplasm
These epigenetic defects occurred in various cancers (e.g. breast, ovarian, colorectal and head and neck). Two or three ... ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term neoplasm is a synonym of tumor. Neoplasia denotes the process of the formation of neoplasms/tumors, and the process is ... The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that ...
Pseudomyxoma peritonei
For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed ... Werth in 1884 coined the term pseudomyxoma peritonei, describing it in association with a mucinous ovarian tumor. In 1901 ... Young RH (May 2004). "Pseudomyxoma peritonei and selected other aspects of the spread of appendiceal neoplasms". Seminars in ... ISBN 978-0-323-35909-2. Sugarbaker PH (January 2006). "New standard of care for appendiceal epithelial neoplasms and ...
Prostate cancer
"Male Genitals - Prostate Neoplasms". Pathology study images. University of Virginia School of Medicine. Archived from the ... Mutations in BRCA1 and BRCA2 (important risk factors for ovarian cancer and breast cancer in women) have also been implicated. ... PARP inhibitor olaparib is an approved breast/ovarian cancer drug that is undergoing clinical trials. Also in trials for CRPC ...
Downwinders
Several severe adverse health effects, such as an increased incidence of cancers, thyroid diseases, CNS neoplasms, and possibly ... ovarian, lung, colon, and thyroid tissues as the most radiosensitive among women. For example, the FGR 13 has estimated that ... a female fetus may therefore be multigenerational and increase both the daughter's and grandchildren's risks for ovarian cancer ...
Cancer
They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often ... "Screening for Ovarian Cancer". U.S. Preventive Services Task Force. 2004. Archived from the original on 23 October 2010. ... Routine screening is not recommended for bladder cancer, testicular cancer, ovarian cancer, pancreatic cancer, or prostate ... ovarian cancer and colorectal cancer. Diagnosing a new cancer in a pregnant woman is difficult, in part because any symptoms ...
H19 (gene)
... adrenocortical neoplasms, choriocarcinomas, hepatocellular carcinomas, bladder cancers, ovarian serous epithelial cancers, head ... The ovarian cancer patient experienced a 50% decline in the amount of the ovarian cancer marker protein CA-125 in her blood as ... In ovarian cancers, 75% of low malignancy tumors and 65% of invasive ovarian carcinomas are H19 RNA positive. Normal breast ... "Phase 1/2a Study of DTA-H19 in Advanced Stage Ovarian Cancer With Symptomatic Ascites". ClinicalTrials.gov. U.S. National ...
List of skin conditions
Arrhenoblastoma Cretinism Cushing's syndrome Excess ovarian androgen release syndrome (ovarian SAHA syndrome) Familial ... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
Ollier disease
One case study indicates that this is due a mesodermal dysplasia in the long bones resulting in ovarian cancer. The incidence ... While chondrosarcoma is the most common form of a secondary malignant bone neoplasm found in cases of Ollier disease, other ... Early detection and consistent and repeated monitoring is important in order to prevent and treat any potential bone neoplasms ... Clinical and radiological evaluations are conducted in order to detect the presence of bone neoplasms or lesions typically ...
Brain metastasis
Neoplasm Metastasis Cancer Brain tumor Tse V (10 November 2009). "Brain Metastasis". Medscape. Retrieved 13 January 2010. " ... colorectal or ovarian cancers. Brain metastases are most commonly diagnosed within multiple intracranial areas within the ... Percy AK, Elveback LR, Okazaki H, Kurland LT (January 1972). "Neoplasms of the central nervous system. Epidemiologic ... the national survey of intracranial neoplasms". Neurology. 35 (2): 219-26. doi:10.1212/WNL.35.2.219. PMID 3969210. S2CID ...
History of cancer chemotherapy
Later, this agent would also be used to treat lung and ovarian cancers. Cisplatin, a platinum-based compound, was discovered by ... A study of 93 patients with incurable neoplasms". J Natl Med Assoc. 43 (4): 211-240. PMC 2616951. PMID 14850976. Li, MC; Hertz ... to be effective in ovarian cancer therapy. Notably, this agent, although developed by the NCI in partnership with Bristol-Myers ...
Murine respirovirus
Nakamori M, Fu X, Meng F, Jin A, Tao L, Bast RC, Zhang X (July 2003). "Effective therapy of metastatic ovarian cancer with an ... Its expression is also increased in a wide range of other malignant neoplasms. Factor X (F10) is frequently expressed in normal ... It is also overexpressed in some cell lines originating from various malignant neoplasms. Thus, it is highly expressed in ... Some of these proteases are overexpressed in malignant neoplasms. For example, transmembrane serine protease 2 (TMPRSS2), which ...
Interventional radiology
... ovarian vein embolization Ovarian vein embolization is a same-day treatment, which takes place in an interventional radiology ... such as osteoporosis or underlying neoplasm. Analogous to vertebroplasty, the purpose of sacroplasty is to provide ... "Ovarian Vein Embolization". RadiologyInfo. Radiological Society of North America, Inc. (RSNA). January 23, 2017. Strub WM, ... Pelvic congestion syndrome usually affects women who have previously been pregnant, because the ovarian veins and pelvic veins ...
Actinomyces
Another form of actinomycosis is thoracic disease, which is often misdiagnosed as a neoplasm, as it forms a mass that extends ... Joshi C, Sharma R, Mohsin Z. Pelvic actinomycosis: a rare entity presenting as tubo-ovarian abscess. Arch Gynecol Obstet. 2010 ...
Cyclophosphamide
Myeloproliferative neoplasms, including acute leukemia, non-Hodgkin lymphoma and multiple myeloma, occurred in 5 of 119 ... Because of its potential side effects such as amenorrhea or ovarian failure, cyclophosphamide is used for early phases of ... As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer ... Bernatsky S, Clarke AE, Suissa S (February 2008). "Hematologic malignant neoplasms after drug exposure in rheumatoid arthritis ...
Mir-25 microRNA precursor family
Zhang H, Zuo Z, Lu X, Wang L, Wang H, Zhu Z (February 2012). "MiR-25 regulates apoptosis by targeting Bim in human ovarian ... MicroRNA expression pattern in intraductal papillary mucinous neoplasm]". The Korean Journal of Gastroenterology = Taehan ...
Thymidine kinase in clinical chemistry
Lipkin M, Deschner E, Troncale F (1970). "Cell differentiation and the development of colonic neoplasms". CA: A Cancer Journal ... in ovarian cancer, in mesotheliomas, in melanomas, in thyroid tumors in leukemia and in breast cancer. Therapy that influences ... ovarian, cervical and esophageal cancers. There are several non-malignant causes for elevation of thymidine kinase in serum ... "Biochemical measure of the volume doubling time of human pulmonary neoplasms". Cancer. 55 (7): 1530-5. doi:10.1002/1097-0142( ...
List of MeSH codes (C04)
... ovarian neoplasms MeSH C04.588.322.455.398 - granulosa cell tumor MeSH C04.588.322.455.464 - luteoma MeSH C04.588.322.455.531 ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
Polycystic ovary syndrome
Other names for this syndrome include polycystic ovarian syndrome, polycystic ovary disease, functional ovarian ... androgen-secreting neoplasms, and other pituitary or adrenal disorders, should be investigated. History-taking, specifically ... an ovarian volume of at least 10 ml is regarded as an acceptable definition of having polycystic ovarian morphology. rather ... ovarian cysts. These "cysts" are in fact immature ovarian follicles. The follicles have developed from primordial follicles, ...
Camran Nezhat
... full removal of ovarian cysts, and myomectomies (full removal of fibroids), could only be done via laparotomy. Some of these ... cautery of neoplasms, and tubal ligations. When Nezhat began using his new video-laparoscopic technique of operating off the ... cauterizing of neoplasms, biopsies, and tubal ligations. This meant that other, more complicated gynecologic surgical ...
Chemotherapy
Survivors of childhood cancer are more than 13 times as likely to get a secondary neoplasm during the 30 years after treatment ... Female infertility by chemotherapy appears to be secondary to premature ovarian failure by loss of primordial follicles. This ... Roness H, Kalich-Philosoph L, Meirow D (2014). "Prevention of chemotherapy-induced ovarian damage: possible roles for hormonal ... The most common secondary neoplasm is secondary acute myeloid leukemia, which develops primarily after treatment with ...
Fibroblast growth factor receptor 1
These neoplasms were initially regarded as eosinophilias, hypereosinophilias, Myeloid leukemias, myeloproliferative neoplasms, ... of ovarian Papillary serous cystadenocarcinoma (almost all amplifications); ~5% of colorectal cancers (~60 amplifications, 40% ... Unlike many other myeloid neoplasms with eosinophil such as those caused by Platelet-derived growth factor receptor A or ...
Small supernumerary marker chromosome
sSMC i (5)(p10) is also detected in rare cases of ovarian cancer and very rare cases of breast cancers. The mechanism(s) by ... However, it may also be active in causing birth defects and neoplasms (e.g. tumors and cancers). The sSMC's small size makes it ... Surgical removal of the gonads has been recommended to remove the threat of developing these sSMC-associated neoplasms. Tuner ... Panani AD, Roussos C (April 2006). "Non-random structural chromosomal changes in ovarian cancer: i(5p) a novel recurrent ...
Florid cutaneous papillomatosis
It is likely directly induced by an underlying neoplasm secreting a growth factor. One candidate may be alpha-transforming ... ovarian cancer, uterine cancer, prostate cancer[citation needed], lung cancer and cervical cancer. Other associated underlying ...
PAX8
... aka Hurthle-Cell Neoplasms). Expression of PAX8 is increased in neoplastic renal tissues, Wilms tumors, ovarian cancer and ... ovarian cancer cells, bladder, prostate, and endometrial carcinomas. Expression of PAX8 is also induced during the development ...
Fever of unknown origin
Although most neoplasms can present with fever, malignant lymphoma is by far the most common diagnosis of FUO among the ... ovarian cancer atrial myxoma and Castleman disease. In those with HIV currently being treated with antiretroviral therapy and ... neoplasms. In some cases the fever even precedes lymphadenopathy detectable by physical examination. ADEM (acute disseminated ...
Estrogen (medication)
Ovarian extracts were available in the late 1800s and early 1900s, but were inert or had extremely low estrogenic activity and ... "Pharmacology and Clinical Utility of Hormones in Hormone Related Neoplasms". In Alan C. Sartorelli, David G. Johns (eds.). ... Ovarian Function and its Disorders: Diagnosis and Therapy. Springer Science & Business Media. pp. 309-332. doi:10.1007/978-94- ... or primary ovarian failure), amenorrhea, dysmenorrhea, and oligomenorrhea. Estrogens can also be used to suppress lactation ...
Browsing by Subject "Ovarian Neoplasms"
Dual Immunostain With SATB2 and CK20 Differentiates Appendiceal Mucinous Neoplasms From Ovarian Mucinous Neoplasms
... Am J Clin ... Keywords: Appendiceal mucinous neoplasm; CDX2; CK20; Dual immunostain; Ovarian mucinous neoplasm; SATB2; Villin. ... with major differential diagnoses including appendiceal mucinous neoplasm (AMN) and ovarian mucinous neoplasm (OMN). Special AT ... Objectives: Determination of the primary site of origin for mucinous neoplasms identified in the peritoneal and/or pelvic ...
Cureus | A Case Report of Pseudomyxoma Peritonei Arising From Primary Mucinous Ovarian Neoplasms
We report two rare cases of PMP originating from mucinous primary ovarian neoplasms. The case series discusses the cases of ... Patients were diagnosed to have pseudomyxoma peritonei arising from mucinous ovarian tumors. Patients were referred to the ... is a rare manifestation of primary mucinous neoplasms. ... In fact, most mucinous ovarian neoplasms are benign (4 in 5 ... A Case Report of Pseudomyxoma Peritonei Arising From Primary Mucinous Ovarian Neoplasms Reuben Joseph, Ramprasath Sathiamoorthy ...
Peritoneal cancer neoplasm Profilul de risc clinic asociat cancerului ovarian, Peritoneal cancer tumor markers
Peritoneal cancer neoplasm. Peritoneal cancer tumor markers. Conținutul. *High-grade ovarian serous carcinoma in a young woman ... Out of these, 44 Figure peritoneal cancer neoplasm. Clinical risk profile associated with ovarian cancer Distribution of cases ... Constantin: Detalii noutati Peritoneal cancer age Peritoneal cancer neoplasm ovarian serous carcinoma in a young woman - case ... Peritoneal cancer chances of survival Profilul de risc clinic asociat cancerului ovarian Covor de tenă Ovarian high-grade ...
Online Ovarian Neoplasm Imaging 2013
Ovarian Neoplasm Imaging | Radiology Key
Ovarian Tumors (Clinical Setting and US). Sep 3, 2016 by admin in GENERAL RADIOLOGY Comments Off on Ovarian Tumors (Clinical ... Imaging of Ovarian Cancer. Sep 3, 2016 by admin in GENERAL RADIOLOGY Comments Off on Imaging of Ovarian Cancer ... and MR of Benign Ovarian Germ Cell Tumours. Sep 3, 2016 by admin in GENERAL RADIOLOGY Comments Off on and MR of Benign Ovarian ... 1 Origin of all different types of ovarian tumors Most consist of ovarian cell types, but testicular (Sertoli cell) and mixed ...
Does risk for ovarian malignancy algorithm excel human epididymis protein 4 and CA125 in predicting epithelial ovarian cancer:...
ROMA is promising predictors of epithelial ovarian cancer to replace CA125, but its utilization requires further exploration. ... ROMA is helpful for distinguishing epithelial ovarian cancer from benign pelvic mass. HE4 is not better than CA125 either for ... Neoplasms, Glandular and Epithelial / diagnosis* * Neoplasms, Glandular and Epithelial / metabolism * Ovarian Neoplasms / ... Does risk for ovarian malignancy algorithm excel human epididymis protein 4 and CA125 in predicting epithelial ovarian cancer: ...
Results of search for 'su:{Ovarian neoplasms}' › WHO HQ Library catalog
Biology of ovarian neoplasia / edited by E. D. Murphy and W. G. Beamer. by Murphy, E. D , Beamer, W. G , International Union ... Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas / edited by A. T. van Oosterom, F. M. Muggia, F. J. ... Histological typing of ovarian tumours / S. F. Serov, R. E. Scully, in collaboration with L. H. Sobin and pathologists in ten ... Ovarian cancer : screening, treatment, and followup. by National Institutes of Health (U.S..) Office of Medical Applications of ...
Establishing the Incidences of BRCA1 and BRCA2 Mutation by Combining DHPLC and Direct Sequencing in Ovarian Cancer
The incidence of ovarian cancer increased in recent 10 years. Ovarian cancer ind ... Ovarian cancer is the first mortality rate of gynecologic malignancies. ... Ovarian Cancer. *BRCA1 gene, BRCA2 gene, DHPLC, genetic diagnosis. *Ovarian Neoplasms. .map{width:100%;height:300px;margin- ... The incidence of ovarian cancer increased in recent 10 years. Ovarian cancer. indeed is a disease that should be respected, ...
Gynecology Section 17c - Ovarian Neoplasm Introduction and Surface Epithelial Tumors - Physeo
IMSEAR at SEARO: Ovarian neoplasms in childhood and adolescents in Songklanagarind Hospital, February 1983-March 1989.
Ovarian neoplasms in childhood and adolescents in Songklanagarind Hospital, February 1983-March 1989. ... Tintara H, Mitarnun W. Ovarian neoplasms in childhood and adolescents in Songklanagarind Hospital, February 1983-March 1989. ... Ovarian tumors in young females under the age of 20 years in Songklanagarind Hospital from February 1983 to March 1989 were ... The total number of patients was 47, with a 4.0 per cent incidence of ovarian tumors in all age groups. Germ cell tumor was the ...
ARDMS Abdomen + OBGYN Cards - Free download and software reviews - CNET Download
Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian...
Ovarian Neoplasms. Carcinoma, Ovarian Epithelial. Endocrine Gland Neoplasms. Neoplasms by Site. Neoplasms. Ovarian Diseases. ... Genital Neoplasms, Female. Urogenital Neoplasms. Endocrine System Diseases. Gonadal Disorders. Carcinoma. Neoplasms, Glandular ... Genetic and Rare Diseases Information Center resources: Ovarian Cancer Ovarian Epithelial Cancer ... Platinum Resistant Ovarian Cancer. TTFields. Paclitaxel. Minimal toxicity. TTF. Tumor Treating Fields. Novocure. ...
Browsing by Subject
Browsing by Subject
Listening to the Patient Voice Adds Value to Cancer Trials
International Collaboration on Ovarian Neoplasms 7; SF-36 = 36 item Short Form Survey; SQLQ = Supplementary Quality of Life ... Advanced ovarian cancer. Carboplatin paclitaxel vs carboplatin paclitaxel plus bevacizumab. 1528. 890. EORTC QLQ-OV28. EORTC ... ovarian 28); EQ5D = EuroQol 5 dimension; FACIT-F = Functional Assessment Chronic Illness Therapy, fatigue; FACT = Functional ...
Ovarian Cancer | Ovarian Cancer Symptoms | MedlinePlus
Women with ovarian cancer may have no symptoms or mild symptoms until the disease is in an advanced stage. ... ClinicalTrials.gov: Ovarian Neoplasms (National Institutes of Health) * ClinicalTrials.gov: Peritoneal Neoplasms (National ... Ovarian Cancer Statistics (National Cancer Institute) * What Are the Key Statistics about Ovarian Cancer? (American Cancer ... What is ovarian cancer?. Cancer is a disease in which abnormal cells in the body grow out of control and form a tumor. Ovarian ...
Faculty | Division of Reproductive Sciences
November 2006 - Volume 30 - Issue 11 : The American Journal of Surgical Pathology
The Recurrence and the Overall Survival Rates of Ovarian Serous Borderline Neoplasms With Noninvasive Implants is Time ... Ovarian Metastases of Intestinal-Type Gastric Carcinoma: A Clinicopathologic Study of 4 Cases with Contrasting Features to ... Carcinoma by Any Other Name: Pseudomyxoma Peritonei is not Best Viewed With an Ovarian Perspective. Bradley, Robert F.; ...
The Biology and Medical Dynamics of Human Reproduction - Nova Science Publishers
Cystic Teratoma: Practice Essentials, Background, Pathophysiology
... of all ovarian neoplasms. They are the most common ovarian germ cell tumor and also the most common ovarian neoplasm in ... Renewed Calls for Fallopian Tube Removal to Avoid Ovarian Cancer * Advanced Ovarian Cancer: 20% Disease-Free Survival at 10 ... Laparoscopic management of ovarian dermoid cysts: a review of 47 cases. Ann Saudi Med. 2004 Sep-Oct. 24(5):357-60. [QxMD ... Germ cell neoplasms of the testis. Am J Surg Pathol. 1993 Nov. 17(11):1075-91. [QxMD MEDLINE Link]. ...
CDC25A Facilitates Chemo-resistance in Ovarian Cancer Multicellular Spheroids by Promoting E-cadherin Expression and Arresting...
Keywords: Ovarian Neoplasms, Multicellular Spheroids, CDC25A, Drug Resistance, Cell Cycle, and Molecular Targeted Therapy ... Ovarian cancer cells in ascites prefer to aggregate into the multicellular spheroids (MCS) with an inadequate response to ... Sun Y, Li S, Yang L, Zhang D, Zhao Z, Gao J, Liu L. CDC25A Facilitates Chemo-resistance in Ovarian Cancer Multicellular ... Peritoneal metastasis is the most common pathway for the spread of ovarian cancer and one of the major causes of cancer death. ...
Subject: antineoplastic agents / Subject term: antineoplastic activity / Text Availability: Citation in PubAg - PubAg Search...
... neoplasm cells; ovarian neoplasms; paclitaxel; toxicity testing. Abstract:. ... Epithelial ovarian carcinoma is the most lethal ... esophageal neoplasms; glutamine; human health; liver neoplasms; neoplasm cells; pH; pancreatic neoplasms; pollution; research; ... antineoplastic activity; antineoplastic agents; biosynthesis; breast neoplasms; colorectal neoplasms; humans; lung neoplasms; ... lung neoplasms; neoplasm cells. Abstract:. ... In this study, a series of novel naphthalimide-benzotriazole conjugates (1a-3c) ...
Bente Mertz Nørgård - Research output
- University of Southern Denmark
Programs & Events | Sandy Rollman Ovarian Cancer Foundation
Pittsburgh ACTION (Alliance Concentrating on Impacting Ovarian Neoplasms) Consortium. March 1, 2023 ... Facing Ovarian Cancer Facing Ovarian Cancer Coping with a New Diagnosis Treatment Options About Ovarian Cancer Find a Clinical ... An on-going support program for friends of those effected by ovarian cancer. ...
GONAL-F RFF REDI-JECT - Oncology Nurse Advisor
... ovarian neoplasms, congenital malformations. Men: acne, inj site pain, gynecomastia, seborrhea, fatigue. ... Avoid intercourse for women with significant ovarian enlargement after ovulation. Increased risk of ovarian torsion, multi- ... If ovaries are enlarged on last day of therapy, or other evidence of ovarian hyperstimulation syndrome (OHSS) occurs, do not ... Discontinue if evidence of OHSS occurs (eg, excessive number of ovarian follicles seen by serum estradiol levels or ultrasound ...
Ovarian torsion - Symptoms, diagnosis and treatment | BMJ Best Practice
Rapid diagnosis and intervention are necessary to preserve ovarian function where this is ... blocking adequate blood flow to the ovary.Ovarian torsion is a surgical emergency. ... Ovarian torsion (or adnexal torsion) is a twisting of the ovary and/or fallopian tube on its vascular and ligamentous supports ... Ovarian torsion is a surgical emergency. Rapid diagnosis and intervention are necessary to preserve ovarian function where this ...
BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies - Bladder Cancer Advocacy Network
Ovarian Neoplasm. ELIGIBILITY Key Inclusion Criteria. Life expectancy ≥12 weeks.. - Patients must have measurable disease per ... Cohort B-4: Histologically confirmed non-mucinous epithelial ovarian, fallopian tube, or primary peritoneal cancer that is ... or ovarian tumors that recurred after or has been refractory to prior therapy (fresh tumor biopsy or an archived sample testing ...
The Two-dimensional and Three-dimensional T2 Weighted Imaging-based Radiomic Signatures Selected for the Preoperative...
Accurate discrimination between ovarian borderline tumors (BOTs) and malignancies with imaging play an important role in ... management.Purpose: To evaluate the ability of T2-weighted imaging (T2WI)-based radiomics to discriminate ovarian border... ... Ovarian borderline tumors (BOTs) account for approximately 10-15% of epithelial ovarian tumors, with an annual prevalence of ... First, two-sample t-tests were performed to compare MR-based signature values between ovarian BOT and ovarian cancer. Next, the ...
Tumors29
- Patients were diagnosed to have pseudomyxoma peritonei arising from mucinous ovarian tumors. (cureus.com)
- The present case report highlights the significant radio-pathologic characteristics of PMP, which originated from mucinous ovarian tumors. (cureus.com)
- Pseudomyxoma peritonei (PMP) is a rare disease arising from primary mucinous tumors, which are usually appendiceal mucinous epithelial neoplasms and rarely mucinous ovarian tumors [1] . (cureus.com)
- REVIEW-URI This study was performed to evaluate the clinical risk profile of patients with ovarian tumors who were surgically treated, measuring the survival rate at 5 years. (anvelope-janteauto.ro)
- Fig. 1 Typical ultrasound images of (a) benign tumors (b) malignant tumors Methods Our proposed system for ovarian tumor classification is presented in Fig. 2. (radiologykey.com)
- Ovarian tumors in young females under the age of 20 years in Songklanagarind Hospital from February 1983 to March 1989 were evaluated. (who.int)
- The total number of patients was 47, with a 4.0 per cent incidence of ovarian tumors in all age groups. (who.int)
- Some other rarer types of ovarian cancer are malignant germ cell tumors and stromal tumors. (medlineplus.gov)
- Patients with advanced, histologically confirmed pancreatic, breast, non-small-cell lung cancer (NSCLC), gastric, esophageal, head and neck, or ovarian tumors that recurred after or has been refractory to prior therapy (fresh tumor biopsy or an archived sample testing for Nectin-4 expression). (bcan.org)
- The Two-dimensional and Three-dimensional T2 Weighted Imaging-based Radiomic Signatures Selected for the Preoperative Discrimination of Ovarian Borderline Tumors and Epithelial Cancer. (researchsquare.com)
- Accurate discrimination between ovarian borderline tumors (BOTs) and malignancies with imaging play an important role in management. (researchsquare.com)
- To evaluate the ability of T2-weighted imaging (T2WI)-based radiomics to discriminate ovarian borderline tumors (BOTs) from malignancies based on two-dimensional (2D) and three-dimensional (3D) lesion segmentation methods. (researchsquare.com)
- The T2WI radiomics could achieve a higher accuracy in discriminating ovarian tumors. (researchsquare.com)
- Dermoid tumors are mature ovarian teratomas, slow-growing germ cell tumors that are almost always benign. (appliedradiology.com)
- Struma ovarii are ovarian tumors composed of thyroid tissue, with 5-10% being malignant. (appliedradiology.com)
- Primary ovarian carcinoid tumors are exceptionally rare entities accounting for approximately 0.1% of all ovarian neoplasms. (whiterose.ac.uk)
- Although there is no established diagnostic framework for primary ovarian carcinoid tumors, this case was diagnosed as a well-differentiated neuroendocrine tumor, Grade 2 (intermediate grade), arising in association with a mature cystic teratoma/dermoid cyst. (whiterose.ac.uk)
- Biochemistry of Human Cancer focuses on advances in the application of biochemistry to the study of human cancers, such as neoplastic immunoglobulinopathies, cancer of the bladder, tumors of the neural crest, leukemias and lymphomas, and neoplasms of the bone. (elsevier.com)
- The remaining chapters look at the role of enzymes and immunoglobulins in cancer, the tryptophan metabolism in cancer of the bladder and the carcinoid syndrome, the link between amino acid metabolism and tumors of the neural crest, and the neoplasms of the digestive tract and the accessory organs (pancreas and liver). (elsevier.com)
- Reduced MAD2 nuclear intensity was associated with a shorter RFS (P = .03), in ovarian tumors of differing histologic subtype (n = 66). (lenus.ie)
- However, sex cord tumors are the most common ovarian tumor found in these patients. (myriad.com)
- The specific expression within epithelial ovarian tumors was further confirmed by mRNA analysis. (helsinki.fi)
- Epithelial cystic tumors account for about 60% of all true ovarian neoplasms. (medscape.com)
- One third of all ovarian tumors are serous, and two thirds of these serous tumors are benign. (medscape.com)
- Mucinous epithelial tumors account for approximately 10-15% of all epithelial ovarian neoplasms. (medscape.com)
- Solid epithelial ovarian tumors are almost invariably malignant. (medscape.com)
- In this study, we describe characteristic chromosomal alterations in a consecutive series of 96 serous ovarian tumors by comparative genomic hybridization. (elsevier.com)
- Subserous myomas must be distinguished from ovarian tumors. (gafacom.website)
- Ameloblastoma is a benign dental tumor mostly found in the mandible, with several variations El ameloblastoma es un tumor odontogénico benigno que se encuentra mayormente en la mandíbula 80%) usually found in the mandible, making up about 1% of tumors in the oral region.2 ameloblastoma . (udea.edu.co)
Tumor11
- Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. (medlineplus.gov)
- Our results suggest that T2WI-based radiomic features were highly correlated with ovarian tumor subtype classification. (researchsquare.com)
- Preliminary studies have revealed that in the preclinical chicken model, hens develop ovarian tumor naturally at a very high rate that exceeds 25% during 2-4 years of age. (elsevier.com)
- This report describes a primary ovarian neuroendocrine tumor arising in association with a mature cystic teratoma in a 65 year-old woman. (whiterose.ac.uk)
- The rate of endometrial cancer diagnosis was significantly higher in women with endometriosis-associated endometrioid ovarian cancer (33%) than in other patients (11%) (p = 0.04) with a 92% concordance between ovarian and endometrial histologic tumor grade. (elsevier.com)
- Immunohistochemical staining of ovarian tumor tissue arrays showed distinctive cytoplasmic expression pattern only in mucinous carcinomas and suggested differential expression between benign and malignant mucinous neoplasms. (helsinki.fi)
- Pre- and postmenopausal women are considered to have a high risk of ovarian cancer if they have a personal or family history of ovarian cancer, have or are suspected to have BRCA1 or BRCA2 genetic mutations, or have an elevated CA-125 level (antigen 125-a protein elevated in cancer tumor cells) as measured by a blood test. (medscape.com)
- We focus on the cost effectiveness of a novel biomarker combination for detecting ovarian tumor malignancy. (avalonecon.com)
- A recent study investigated the use of novel biomarker combinations of CA125 and other tumor markers, most notably, HE4, an 11 kDa protein that is a precursor to the epididymal secretory protein E4 and is over-expressed in ovarian carcinomas. (avalonecon.com)
- A pelvic the anthrax toxin is being evaluated as a choice for tumor ultrasonograph showed a left ovarian complex mass meas- cell surface targeting in chemoresistant neoplasms (5). (cdc.gov)
- Melanotic Neuroectodermal Tumor of Infancy (MNTI) is a rare neoplasm originating from neural crest El Tumor Neuroectodérmico Melanocítico de la Infancia (TNEMI) es una neoplasia infrecuente neuroectodermal tumor of infancy. (udea.edu.co)
Developing ovarian cancer1
- The proposed research is significant because a positive outcome of this pilot study would lead to further testing of metformin in a population of euglycemic women who are at risk for developing ovarian cancer. (elsevier.com)
Cancer132
- The trend of incidence of ovarian cancer was studied, the 5-year survival rate calculated and prognostic factors for survival determined. (who.int)
- Peritoneal cancer neoplasm. (anvelope-janteauto.ro)
- Constantin: Detalii noutati Peritoneal cancer age Peritoneal cancer neoplasm ovarian serous carcinoma in a young woman - case report and literature review Peritoneal cancer age Peritoneal cancer end stage. (anvelope-janteauto.ro)
- Most of the patients with malignant disease were multiparous Moreover, from menopausal patients, the higher prevalence was seen at the group between 45 and 55 years old, not being peritoneal cancer neoplasm on the earlier appearance. (anvelope-janteauto.ro)
- Thus, our study shows the need to create a screening for patients at risk for ovarian cancer which present higher age, multiparity, early menarche, polycystic ovaries association, and higher serum CA marker values. (anvelope-janteauto.ro)
- The survival rate at five years of folow-up shows a higher incidence peritoneal cancer age peritoneal cancer peritoneal cancer neoplasm stage in patients under 30 years old, probably due to the earlier stages detected. (anvelope-janteauto.ro)
- Profilul de risc clinic asociat cancerului ovarian Most of the patients with malignant disease were multiparous Moreover, from menopausal patients, the higher prevalence was seen at the group between 45 and 55 years old, not being dependent on the peritoneal cancer while pregnant appearance. (anvelope-janteauto.ro)
- The peritoneal cancer while pregnant cancer while pregnant peritoneal cancer neoplasm of gynecological pathology was seen in women with polycystic ovaries i. (anvelope-janteauto.ro)
- Managementul perioperator al unui pacient cu tumoră Krukenberg - studiu de caz Peritoneal cancer with ascites Ovarian high-grade serous carcinoma is a type of malignancy that is rare among young adult women, being more frequent in postmenopausal wo-men. (anvelope-janteauto.ro)
- Fig. 1 A 83-year-old woman with newly diagnosed left ovarian cancer (SUV max 8.7) Technique for PET/CT Proper patient preparation and scanning protocol are needed for optimal diagnostic accuracy. (radiologykey.com)
- Risk for Ovarian Malignancy Algorithm (ROMA) and Human epididymis protein 4 (HE4) appear to be promising predictors for epithelial ovarian cancer (EOC), however, conflicting results exist in the diagnostic performance comparison among ROMA, HE4 and CA125. (nih.gov)
- ROMA is helpful for distinguishing epithelial ovarian cancer from benign pelvic mass. (nih.gov)
- ROMA is promising predictors of epithelial ovarian cancer to replace CA125, but its utilization requires further exploration. (nih.gov)
- Therapeutic progress in ovarian cancer, testicular cancer and the sarcomas / edited by A. T. van Oosterom, F. M. Muggia, F. J. Cleton. (who.int)
- Ovarian cancer : screening, treatment, and followup. (who.int)
- Ovarian cancer is the first mortality rate of gynecologic malignancies. (knowcancer.com)
- The incidence of ovarian cancer increased in recent 10 years. (knowcancer.com)
- Ovarian cancer indeed is a disease that should be respected, however, there were only few of research work focusing on it in Taiwan. (knowcancer.com)
- To study the mechanisms of carcinogenesis of ovarian cancer will help us understand this disease and develop new strategies of diagnosis and prevention for ovarian cancer in the future. (knowcancer.com)
- To our present knowledge, carcinogenesis of ovarian cancer has strong correlation with some special genes such as BRCA1 and BRCA2 genes. (knowcancer.com)
- The incidences of BRCA1 or BRCA2 gene mutation even increase to 30-50% in the population of familial ovarian cancer. (knowcancer.com)
- Women with BRCA1 gene mutation have 80% to get breast cancer before the age of 70 and 63% of them would get ovarian cancer before the age of 70. (knowcancer.com)
- It will become a most powerful tool to establish the database of BRCA1 or BRCA2 gene mutation of the ovarian cancer patients in Taiwan, when we can use the technique of DHPLC combining with the direct DNA sequencing. (knowcancer.com)
- First, we will utilize the new technique of DHPCL with direct DNA sequence to set up the database of BRCA1 and BRCA2 gene mutation of ovarian cancer patients in Taiwan. (knowcancer.com)
- Second, we would lie to set up the new technique of DHPLC combining with direct DNA sequencing in the genetic diagnosis of ovarian cancer patients for the future clinical service in our hospital. (knowcancer.com)
- What is ovarian cancer? (medlineplus.gov)
- What are the types of ovarian cancer? (medlineplus.gov)
- There are a few different types of ovarian cancer. (medlineplus.gov)
- These two cancers are similar to ovarian cancer, and they have the same treatments. (medlineplus.gov)
- So some medical experts also consider those two types as ovarian cancer. (medlineplus.gov)
- Ovarian cancer happens when there are changes (mutations) in the genetic material (DNA). (medlineplus.gov)
- Ovarian cancer that is caused by inherited genetic changes is called hereditary ovarian cancer. (medlineplus.gov)
- There are also certain genetic changes that can raise your risk of ovarian cancer, including changes called BRCA1 and BRCA2 . (medlineplus.gov)
- Besides genetics, your lifestyle and the environment can affect your risk of ovarian cancer. (medlineplus.gov)
- Who is more likely to develop ovarian cancer? (medlineplus.gov)
- Certain people are more likely to develop ovarian cancer. (medlineplus.gov)
- What are the symptoms of ovarian cancer? (medlineplus.gov)
- Ovarian cancer may not cause early signs or symptoms. (medlineplus.gov)
- How is ovarian cancer diagnosed? (medlineplus.gov)
- Often the only way to know for sure that you have ovarian cancer is by having a biopsy of the tissue. (medlineplus.gov)
- What are the treatments for ovarian cancer? (medlineplus.gov)
- Your provider may suggest that you have genetic testing to look for the gene changes that raise the risk for ovarian cancer. (medlineplus.gov)
- Sun Y, Li S, Yang L, Zhang D, Zhao Z, Gao J, Liu L. CDC25A Facilitates Chemo-resistance in Ovarian Cancer Multicellular Spheroids by Promoting E-cadherin Expression and Arresting Cell Cycles. (jcancer.org)
- Peritoneal metastasis is the most common pathway for the spread of ovarian cancer and one of the major causes of cancer death. (jcancer.org)
- Ovarian cancer cells in ascites prefer to aggregate into the multicellular spheroids (MCS) with an inadequate response to chemotherapy. (jcancer.org)
- In this study, gene expression analysis implicated that ovarian cancer MCS had its unique expression pattern and the cell cycle-related pathways were prominently altered in MCS cells compared to the monolayer adherent cells. (jcancer.org)
- Loss-of-function studies showed that CDC25A promoted cisplatin-resistance and paclitaxel-resistance and inhibited the drug-induced apoptosis in ovarian cancer MCS. (jcancer.org)
- Accordingly, addition of NSC95397, a small molecular inhibitor of CDC25A, sensitized the ovarian cancer MCS to chemotherapeutic agents. (jcancer.org)
- This provides us a novel strategy for the treatment of ovarian cancer peritoneal metastasis and may help improve the overall survival of ovarian cancer patients. (jcancer.org)
- An on-going support program for friends of those effected by ovarian cancer. (sandyovarian.org)
- A virtual ovarian cancer support group. (sandyovarian.org)
- To date, there have been limited MRI radiomics studies concerning ovarian BOT and epithelial cancer categorization. (researchsquare.com)
- Ovarian cancer is the most lethal gynecological disease affecting women. (elsevier.com)
- Cancer prevention strategies, therefore, assume a greater importance in reducing the incidence of ovarian cancer. (elsevier.com)
- Several retrospective surveys have found indirect clinical evidence that metformin intake is correlated with greater survival in cancer patients including ovarian cancer patients. (elsevier.com)
- However, there are no prospective clinical studies to suggest that metformin intake reduces the incidence and/or severity of ovarian cancer. (elsevier.com)
- We seek to address this critical gap in knowledge by conducting a pilot preclinical study utilizing a naturally and spontaneously occurring ovarian cancer model. (elsevier.com)
- Metastatic ovarian cancer cells isolated from the chickens were found to be aggressive and invasive and expressed genes and proteins commonly found in human ovarian cancer cells. (elsevier.com)
- Ovarian cancer stem cells recovered from ascites formed extensive network of ovospheres and were found to be highly invasive. (elsevier.com)
- and 2) determine the extent to which metformin affects invasiveness and viability of ovarian cancer stem cells. (elsevier.com)
- Under the second aim, ovarian cancer stem cells isolated from the hen model will be treated with various levels of metformin. (elsevier.com)
- Furthermore, this research will utilize ovarian cancer stems cells isolated from hens to test their susceptibility to metformin treatment. (elsevier.com)
- Our study's objective was to elucidate the role of ovarian cancer microenvironment in regulating the immunosuppressive function of CD11. (researchgate.net)
- The maximum tolerated dose of DNR-GA3 in nude mice bearing s.c. human ovarian cancer xenografts was 6-10 times higher than that of DNR. (elsevier.com)
- The anti-tumour effects of DNR-GA3 and DNR were investigated in four different human ovarian cancer xenografts OVCAR-3, FMa, A2780 and MRI-H-207 at a mean tumour size between 100 and 200 mm 3 . (elsevier.com)
- The book explains the metabolism of purines and pyrimidines in cancer, hypercalcemia in neoplastic disease without evidence of bone metastases, and neoplasms of other organs, such as the pituitary gland, thyroid, testis, and adrenal cortex. (elsevier.com)
- We have investigated clinical and histologic features of endometriosis-associated endometrioid ovarian cancer using an institutional retrospective database. (elsevier.com)
- Methods: Patients diagnosed with endometrioid ovarian cancer at our institution were divided into two groups according to the fulfillment or not of Sampson's and Scott's criteria for the detection of endometriosis-associated ovarian cancer. (elsevier.com)
- Multivariate analysis was performed using the Cox proportional hazards regression model to establish independent factors associated with endometriosis-associated endometrioid ovarian cancer and to identify predictors of survival. (elsevier.com)
- Conclusions: The analysis of a retrospective endometrioid ovarian cancer database may allow to suggest a 40 molecular, morphological and clinical parallelism between endometrial and endometrioid ovarian cancers. (elsevier.com)
- Spindle assembly checkpoint protein expression correlates with cellular proliferation and shorter time to recurrence in ovarian cancer. (lenus.ie)
- Patient and Genetic Counselor Perceptions of In-Person versus Telephone Genetic Counseling for Hereditary Breast/ovarian Cancer. (gwu.edu)
- The objective of this study was to identify histotype-specific serum biomarkers for mucinous ovarian cancer. (helsinki.fi)
- The expression level of the candidate gene in serum was compared to the serum CA125 and HE4 levels in a patient cohort of prospectively collected advanced ovarian cancer. (helsinki.fi)
- Database searches identified REG4 as a potential biomarker with specificity for the mucinous ovarian cancer subtype. (helsinki.fi)
- Finally, an ELISA based serum biomarker assay demonstrated increased expression only in patients with mucinous ovarian cancer. (helsinki.fi)
- This study identifies REG4 as a potential serum biomarker for histotype-specific detection of mucinous ovarian cancer and suggests serum REG4 measurement as a non-invasive diagnostic tool for postoperative follow-up of patients with mucinous ovarian cancer. (helsinki.fi)
- Background: Regulatory T (Treg) cells, a subset of CD4+ T lymphocytes, are mediators of immunosuppression in cancer, and, thus, variants in genes encoding Treg cell immune molecules could be associated with ovarian cancer. (elsevier.com)
- Methods: In a population of 15,596 epithelial ovarian cancer (EOC) cases and 23,236 controls, we measured genetic associations of 1,351 SNPs in Treg cell pathway genes with odds of ovarian cancer and tested pathway and gene-level associations, overall and by histotype, for the 25 genes, using the admixture likelihood (AML) method. (elsevier.com)
- The most significant single SNP associations were tested for correlation with expression levels in 44 ovarian cancer patients. (elsevier.com)
- On behalf of the Australian Ovarian Cancer Study Group 2016, ' Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer ', Oncotarget , vol. 7, no. 43, pp. 69097-69110. (elsevier.com)
- Objective To explore the clinical and biological prognostic factors for advanced ovarian cancer patients receiving first-line treatment with carboplatin, paclitaxel, and bevacizumab. (bmj.com)
- Subiecte ovarian cancer jokes Sex Cervixul face legatura intre papiloma humano laringe si vagin. (etigararunway.ro)
- Inainte papiloma humano laringe aparitia cancerului, celulele colului cervical se transforma, ovarian cancer jokes numit displazie, si devin celule anormale ale tesutului cervical. (etigararunway.ro)
- Ovarian cancer natural treatment Research Cures Cancer - Ovarian Cancer - MedscapeTV oxiuri de la ce apar Hpv foot warts treatment ovarian cancer jokes cancer head, human papillomavirus infection deadly hpv virus gyogyitasa. (etigararunway.ro)
- New Treatments for Ovarian Cancer papilloma on side of tongue Virus del papiloma humano biologia molecular papiloma ovarian cancer jokes se cura si o no, schistosomiasis meaning in tamil cancer sarcoma leg. (etigararunway.ro)
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- Ovarian cancer natural treatment - fotobiennale. (etigararunway.ro)
- Hpv warts ovarian cancer keychain mouth wart treatment that works, cancer de pancreas y diarrea papiloma humano femenino. (etigararunway.ro)
- Ovarian cancer survivor shares advice for newly diagnosed ovarian cancer patients detoxifierea ovarian cancer jokes natural Once successful, these could be of value to women struggling with infertility or cancer patients who cannot conceive after undergoing radiation or chemotherapy. (etigararunway.ro)
- Such treatment is, medicamente parazite eficiente, not ovarian cancer jokes for patients who have a risk of malignant cells in their frozen ovarian tissue. (etigararunway.ro)
- In that case, ovarian tissue cannot be re-implanted because of the chances that their cancer could return. (etigararunway.ro)
- Oxiuros mickey mouse, μέτρο 13 εξισωτική αποζημίωση Sneaker10 Developing a transplantable artificial ovary with isolated follicles from their tissue could therefore offer ovarian cancer keychain women more possibilities for them to conceive. (etigararunway.ro)
- Eat ovarian cancer jokes Heal During Cancer Treatment squamous papilloma description Invatam impreuna Alimente cu maxima influenta in prevenirea si vindecarea cancerului ovarian Cancerul ovarian este una dintre cele mai periculoase boli ovarian cancer jokes. (etigararunway.ro)
- Este a cincea cauza de cancer mortal printre femeile din SUA - o uimitoare cifra de 14 ovarian cancer jokes 23 de femei diagnosticate in fiecare an. (etigararunway.ro)
- Ovarian cancer jokes 4 Ovarian Cancer Symptoms That Every Woman Needs To Know viermi la copii ca un tratament Vitamin c dysbiosis fulminant human papillomavirus hpv infection, ovarian cancer month vulgaires machins parazite parolele. (etigararunway.ro)
- What is Ovarian Cancer: 10 things you should know about ovarian cancer - Cancer Research UK unde în corp Ovarian cancer jokes Divertis, duminica, la Pro Tv Apasă pentru a vedea ovarian cancer jokes originală «ultrasound scan» în dicționarul Engleză dictionary. (etigararunway.ro)
- Ecografia medicală Medical ultrasonography Diagnosticul sonografic ovarian cancer jokes o tehnică de diagnosticare bazată pe ultrasunete utilizată pentru ovarian cancer jokes structurilor interne ale corpului, inclusiv a tendoanelor, mușchilor, articulațiilor, vaselor și organelor interne pentru posibilele ovarian cancer jokes sau leziuni. (etigararunway.ro)
- High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is the most common and deadliest type of ovarian cancer. (houstonmethodist.org)
- Elucidating the precise cell(s) of origin of HGSC will be critical for improving the early detection and prevention of ovarian cancer, ultimately reducing ovarian cancer mortality. (houstonmethodist.org)
- En 11 annees (1er janvier 1998-31 decembre 2008) 9946 patientes ont ete operes dans notre servie dont 29 pour le cancer de l'ovaire soit 0;29. (bvsalud.org)
- Newer markers for ovarian cancer are on the horizon. (medscape.com)
- In women desiring future fertility who have stage IA low-risk ovarian cancer, conservative surgical therapy is appropriate, provided that close follow-up can be maintained. (medscape.com)
- however, improvements in identification of women at high risk for ovarian cancer, as well as improved imaging techniques, have increased the likelihood of early detection. (medscape.com)
- this is indicative of ovarian cancer. (medscape.com)
- Guidelines on ovarian cancer screening and diagnosis have been published by a number of professional medical organizations. (medscape.com)
- The ACR appropriateness criteria does not recommend that women at average risk for ovarian cancer receive screening imaging. (medscape.com)
- Women at a high risk of ovarian cancer may benefit from screening. (medscape.com)
- The recommended imaging test to screen for ovarian cancer is ultrasound (US) to visualize the ovaries. (medscape.com)
- CT and MRI are usually not appropriate for screening women with either average or high risk of ovarian cancer. (medscape.com)
- Study of Nemvaleukin Alfa in Combination with Pembrolizumab Versus Investigator's Choice Chemotherapy in Patients with Platinum-Resistant Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer. (who.int)
- A 29-year-old female with von Recklinghausen's disease developed ovarian epithelial cancer. (uab.cat)
- Bobbie J. Rimel, MD, discusses how PARP inhibitors are deployed across different treatment settings of ovarian cancer, the recent market withdrawal of PARP inhibitors in later-line indications, and ongoing research efforts at Cedars-Sinai Medical Center for patients with ovarian cancer. (onclive.com)
- Without head-to-head comparative data, testing for the presence of BRCA mutations and homologous recombination-deficient (HRD) status remain the optimal ways to select between the PARP inhibitors olaparib (Lynparza), niraparib (Zejula), or rucaparib (Rubraca) for maintenance treatment of patients with ovarian cancer, according to Bobbie J. Rimel, MD. (onclive.com)
- My discussion mostly centered on the use of PARP inhibitors in up-front maintenance for patients with ovarian cancer after they have completed their up-front chemotherapy. (onclive.com)
- For patients who have HRD ovarian cancer as defined by the approved companion diagnostic test, we can use niraparib or olaparib. (onclive.com)
- According to estimates from the World Health Organization, 8.3 million people worldwide died from cancer and other neoplasms in 2008-about 14% of all deaths. (avalonecon.com)
- The use of other biomarkers and combinations of biomarkers in the management of ovarian cancer appears very promising. (avalonecon.com)
- A recent report from the United Kingdom suggests that the use of longitudinal CA-125 values used in combination with subsequent ultrasound evaluation has a high sensitivity and specificity when used in screening for ovarian cancer. (avalonecon.com)
- When CA-125 is used in combination with other biomarkers (and traditional RMI data) in the detection of ovarian cancer, substantially higher sensitivity can be achieved. (avalonecon.com)
- HE4 is a useful tool in detecting ovarian cancer due to minimal gene expression or production of HE4 in normal, cancer-free ovarian tissue. (avalonecon.com)
- For Stage I disease only, HE4 alone had the highest sensitivity for detection of ovarian cancer (46.2% sensitivity at 90% specificity) compared with combinations, particularly at higher levels of specificity. (avalonecon.com)
- For the pre- and post-menopausal groups combined, the novel combination marker was able to correctly classify 93.8% of patients diagnosed with epithelial ovarian cancer. (avalonecon.com)
- When a test or testing algorithm is used for population-based ovarian cancer screening, accuracy requirements are highest. (avalonecon.com)
- News about a long-suspected cause and updated guidelines helped make ovarian cancer this week's top trending clinical topic. (medscape.com)
- Results from the largest reported investigation to date suggest that the use of powder in the genital area does not increase the risk for ovarian cancer . (medscape.com)
- Multibillion-dollar lawsuits have argued that baby powder use caused ovarian cancer and asbestos-related mesothelioma . (medscape.com)
- However, this pooled analysis of data in four large US cohorts found no statistically significant association between the use of powder in the genital area and increased risk for ovarian cancer. (medscape.com)
- In news more specific to ovarian cancer, the National Comprehensive Cancer Network (NCCN) recently published updates to its guidelines on genetic/familial high-risk assessment for ovarian cancer and breast cancer . (medscape.com)
- From the possible exclusion of a rumored cause to key information on diagnosis and mortality, significant recent news about ovarian cancer helped make it this week's top trending clinical topic. (medscape.com)
- Trending Clinical Topic: Ovarian Cancer - Medscape - Jan 17, 2020. (medscape.com)
- In particular, overactive JAK signalling is linked to the development of cancer-like conditions called myeloproliferative neoplasms (MPNs) - which include polycythemia vera, essential thrombocythemia and primary myelofibrosis - as well as certain acute childhood leukaemias . (edu.au)
Prostatic Neoplasms1
- It then discusses the important biochemical aspects of pulmonary and prostatic neoplasms, including the serum acid and alkaline phosphatase activities of prostatic carcinoma. (elsevier.com)
Carcinoma2
- Objective: Due to the increasing prevalence of the benign condition, ovarian carcinoma arising from endometriosis is emerging as a relevant clinical entity with an unclear biological signature. (elsevier.com)
- Ovarian carcinoma (OC) is the most lethal of the gynecological malignancies, often presenting at an advanced stage. (lenus.ie)
Benign5
- The ovarian lesion was sent for further histopathological evaluation, which showed simple, non-stratified, mucinous epithelium with small basally located nuclei lacking cytological atypia, consistent with benign mucinous ovarian cystadenoma (Figure 3 ). (cureus.com)
- Ovarian neoplasms range from benign to malignant and may be primary or secondary. (appliedradiology.com)
- We present the case of a 30-year-old woman with findings of massive ovarian oedema on ultrasound imaging, and a discussion and literature review aiming to clarify that this is a benign tumour-like condition which every gynaecologist can encounter and that the most appropriate treatment is conservative surgery. (who.int)
- These neoplasms can be benign or malignant. (bvsalud.org)
- Uterine leiomyoma is the most common benign neoplasm of the female genital tract. (gafacom.website)
Ovary3
- Ovarian torsion (or adnexal torsion) is a twisting of the ovary and/or fallopian tube on its vascular and ligamentous supports, blocking adequate blood flow to the ovary. (bmj.com)
- Ovarian torsion is a twisting, or torsion, of the ovary around its ligamentous supports. (bmj.com)
- This can be easily mistaken for neoplasm, in which case the appropriate treatment will be removal of the whole ovary. (who.int)
Peritoneal1
- Determination of the primary site of origin for mucinous neoplasms identified in the peritoneal and/or pelvic cavities may be challenging, with major differential diagnoses including appendiceal mucinous neoplasm (AMN) and ovarian mucinous neoplasm (OMN). (nih.gov)
Biomarkers1
- Preoperative diagnostics of ovarian neoplasms rely on ultrasound imaging and the serum biomarkers CA125 and HE4. (helsinki.fi)
Diagnosis1
- Rapid diagnosis and intervention are necessary to preserve ovarian function where this is clinically appropriate and it is important to maintain fertility. (bmj.com)
Cancers5
- Most ovarian cancers are caused by genetic changes that happen during your lifetime. (medlineplus.gov)
- L'objectif de cette étude était de déterminer la fréquence des cancers gynécologiques en pratique oncologique à Lomé et d'en étudier les aspects épidémiologiques et histo-cliniques. (bvsalud.org)
- Il s'agitd'une étude rétrospective et descriptive portant sur tous les cancers gynécologiques reçus en oncologie entre le 1erJanvier 2016 et le 31 Décembre 2021. (bvsalud.org)
- ces cancers ont ete diagnostiques au stade avance d'ou les difficultes dans leur prise en charge chirurgicale. (bvsalud.org)
- En consequence notre objectif a ete d'etudier la place et les caracteres de la chirurgie dans la prise en charge de ces cancers. (bvsalud.org)
Pelvic3
- Together with allergy symptoms such as swelling of lips, tongue, or face or hives in some patients may appear the following conditions: ovarian enlargement presenting as abdominal or pelvic pain, flushing, nausea, vomiting, or diarrhea, blurred vision, headache, abnormal uterine bleeding. (canadianmopharmacy.com)
- A pelvic ultrasonograph showed a left ovarian complex mass measuring 14 cm x 9 cm x 6 cm as well as a moderate amount of free fluid in the cul-de-sac. (cdc.gov)
- Tubo-ovarian abscess is an end-stage disease of acute pelvic inflammatory disease(PID). (e-cep.org)
Cysts1
- Ovarian cysts or enlargement. (oncologynurseadvisor.com)
Infertility1
- Induction of ovulation and pregnancy in patients with functional anovulatory infertility without primary ovarian failure. (oncologynurseadvisor.com)
Adnexal2
- Adnexal masses often are indeterminate at ultrasound, the diagnostic imaging modality of choice in the workup of women with symptoms of such entities, and confirming ovarian etiology can be difficult. (appliedradiology.com)
- Massive ovarian oedema is an uncommon cause of adnexal mass, first described by Kalstone in 1969 [1-7]. (who.int)
Ultrasound2
- Discontinue if evidence of OHSS occurs (eg, excessive number of ovarian follicles seen by serum estradiol levels or ultrasound, abdominal pain). (oncologynurseadvisor.com)
- Ultrasound examination showed a large left ovarian hypoechoic homogenous solid mass lesion 7 × 6 cm ( Figure 1 ), which showed poor vascularity on colour Doppler scan. (who.int)
Tumours6
- A detailed study was performed in 14 patients with epithelial ovarian tumours using the satellite probes 33. (edu.au)
- Somatic changes were evident in approximately 70% of ovarian tumours, the most common being a deletion or reduction in intensity of a band suggesting loss of heterozygosity. (edu.au)
- Using DNA fingerprint analyis ovarian tumours were shown to be heterogeneous with different DNA patterns observed in different sites in five of eight patients. (edu.au)
- This study clearly demonstrates that DNA fingerprint analysis is a sensitive method to detect somatic changes in tumour DNA and for investigating the development of clonal heterogeneity in ovarian tumours. (edu.au)
- We determined the histo-pathological features of surgically removed ovarian tumours. (bvsalud.org)
- Results: The highest incidence of ovarian tumours was within the age range of 20-45 years. (bvsalud.org)
Patients5
- A total of 95 patients with pathologically proven ovarian BOTs and 101 patients with malignancies were retrospectively included in this study. (researchsquare.com)
- Therefore, preoperative identification of patients with ovarian lesions suspected of being BOTs may be helpful in their management. (researchsquare.com)
- Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine mass, and cervical lesions, will be recruited. (biomedcentral.com)
- They comprise less than 0.1% of ovarian neoplasms and are usually found in young patients (average 25 years). (pathologyoutlines.com)
- patients often present with ovarian torsion. (medscape.com)
Left ovarian3
Develop ovarian1
- This case highlights the need to develop ovarian diagnostic criteria in this area. (whiterose.ac.uk)
Testicular neoplasms1
- Ovarian and testicular neoplasms. (univr.it)
Torsion3
- Increased risk of ovarian torsion, multi-fetal gestation and births, ectopic pregnancy, spontaneous abortion. (oncologynurseadvisor.com)
- Ovarian torsion is a surgical emergency. (bmj.com)
- B. anthracis ovarian mass torsion. (cdc.gov)
Mucinous ovarian1
- September 19, 2022) A Case Report of Pseudomyxoma Peritonei Arising From Primary Mucinous Ovarian Neoplasms. (cureus.com)
Primary ovarian1
- We report two rare cases of PMP originating from mucinous primary ovarian neoplasms. (cureus.com)