AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth Care
Otitis MediaOtitis Media with EffusionPleural EffusionOtitis Media, SuppurativeEar, MiddleOtitis ExternaPericardial EffusionPleural Effusion, MalignantMiddle Ear VentilationChinchillaEustachian TubeOtitisOtoscopyHaemophilus influenzaeCulture MediaMastoiditisAcoustic Impedance TestsHaemophilus InfectionsPneumococcal InfectionsAcute DiseaseTympanic MembraneExudates and TransudatesTympanic Membrane PerforationMoraxellaceae InfectionsLabyrinthitisStreptococcus pneumoniaeMoraxella (Branhamella) catarrhalisNasopharynxOtolaryngologyAmoxicillin-Potassium Clavulanate CombinationCholesteatoma, Middle EarTuberculosis, PleuralLymphoma, Primary EffusionAdenoidsEar DiseasesAmoxicillinTympanoplastyOtoscopesMastoidHearing LossRespiratory Tract InfectionsSulfisoxazoleDiagnostic Techniques, OtologicalEaracheAdenoidectomyRecurrenceEar CanalPericardiocentesisCardiac TamponadePneumococcal VaccinesNeisseriaceae InfectionsAnti-Bacterial AgentsPleuraVaccines, ConjugateChronic DiseaseHearing TestsChild Day Care CentersEmpyema, PleuralSinusitisSubdural EffusionAzithromycinCefaclorMucous MembraneHearing Loss, ConductivePleurodesisDisease Models, AnimalAudiometryBacterial InfectionsXylitolNasopharyngeal DiseasesAscitic FluidProspective StudiesMass MediaOtologic Surgical ProceduresPleural CavityHydrothoraxDrainageMyringoplastyParacentesisTreatment OutcomeAntibodies, BacterialPericarditisEar OssiclesStreptolysinsChylothoraxCefuroximeInfant, NewbornFacial ParalysisHaemophilus VaccinesHuman bocavirusRetrospective StudiesCerumenTime FactorsHerpesvirus 8, HumanCulture Media, ConditionedAscites
Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.Otitis Media, Suppurative: Inflammation of the middle ear with purulent discharge.Ear, Middle: The space and structures directly internal to the TYMPANIC MEMBRANE and external to the inner ear (LABYRINTH). Its major components include the AUDITORY OSSICLES and the EUSTACHIAN TUBE that connects the cavity of middle ear (tympanic cavity) to the upper part of the throat.Otitis Externa: Inflammation of the OUTER EAR including the external EAR CANAL, cartilages of the auricle (EAR CARTILAGE), and the TYMPANIC MEMBRANE.Pericardial Effusion: Fluid accumulation within the PERICARDIUM. Serous effusions are associated with pericardial diseases. Hemopericardium is associated with trauma. Lipid-containing effusion (chylopericardium) results from leakage of THORACIC DUCT. Severe cases can lead to CARDIAC TAMPONADE.Pleural Effusion, Malignant: Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.Middle Ear Ventilation: Ventilation of the middle ear in the treatment of secretory (serous) OTITIS MEDIA, usually by placement of tubes or grommets which pierce the TYMPANIC MEMBRANE.Chinchilla: A genus of the family Chinchillidae which consists of three species: C. brevicaudata, C. lanigera, and C. villidera. They are used extensively in biomedical research.Eustachian Tube: A narrow passageway that connects the upper part of the throat to the TYMPANIC CAVITY.Otitis: Inflammation of the ear, which may be marked by pain (EARACHE), fever, HEARING DISORDERS, and VERTIGO. Inflammation of the external ear is OTITIS EXTERNA; of the middle ear, OTITIS MEDIA; of the inner ear, LABYRINTHITIS.Otoscopy: Examination of the EAR CANAL and eardrum with an OTOSCOPE.Haemophilus influenzae: A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.Culture Media: Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.Mastoiditis: Inflammation of the honeycomb-like MASTOID BONE in the skull just behind the ear. It is usually a complication of OTITIS MEDIA.Acoustic Impedance Tests: Objective tests of middle ear function based on the difficulty (impedance) or ease (admittance) of sound flow through the middle ear. These include static impedance and dynamic impedance (i.e., tympanometry and impedance tests in conjunction with intra-aural muscle reflex elicitation). This term is used also for various components of impedance and admittance (e.g., compliance, conductance, reactance, resistance, susceptance).Haemophilus Infections: Infections with bacteria of the genus HAEMOPHILUS.Pneumococcal Infections: Infections with bacteria of the species STREPTOCOCCUS PNEUMONIAE.Acute Disease: Disease having a short and relatively severe course.Tympanic Membrane: An oval semitransparent membrane separating the external EAR CANAL from the tympanic cavity (EAR, MIDDLE). It contains three layers: the skin of the external ear canal; the core of radially and circularly arranged collagen fibers; and the MUCOSA of the middle ear.Exudates and Transudates: Exudates are fluids, CELLS, or other cellular substances that are slowly discharged from BLOOD VESSELS usually from inflamed tissues. Transudates are fluids that pass through a membrane or squeeze through tissue or into the EXTRACELLULAR SPACE of TISSUES. Transudates are thin and watery and contain few cells or PROTEINS.Tympanic Membrane Perforation: A temporary or persistent opening in the eardrum (TYMPANIC MEMBRANE). Clinical signs depend on the size, location, and associated pathological condition.Moraxellaceae Infections: Infections with bacteria of the family MORAXELLACEAE.Labyrinthitis: Inflammation of the inner ear (LABYRINTH).Streptococcus pneumoniae: A gram-positive organism found in the upper respiratory tract, inflammatory exudates, and various body fluids of normal and/or diseased humans and, rarely, domestic animals.Moraxella (Branhamella) catarrhalis: Gram-negative aerobic cocci of low virulence that colonize the nasopharynx and occasionally cause MENINGITIS; BACTEREMIA; EMPYEMA; PERICARDITIS; and PNEUMONIA.Nasopharynx: The top portion of the pharynx situated posterior to the nose and superior to the SOFT PALATE. The nasopharynx is the posterior extension of the nasal cavities and has a respiratory function.Otolaryngology: A surgical specialty concerned with the study and treatment of disorders of the ear, nose, and throat.Amoxicillin-Potassium Clavulanate Combination: A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.Cholesteatoma, Middle Ear: A mass of KERATIN-producing squamous EPITHELIUM that resembles an inverted (suck-in) bag of skin in the MIDDLE EAR. It arises from the eardrum (TYMPANIC MEMBRANE) and grows into the MIDDLE EAR causing erosion of EAR OSSICLES and MASTOID that contains the INNER EAR.Tuberculosis, Pleural: Tuberculosis of the serous membrane lining the thoracic cavity and surrounding the lungs.Lymphoma, Primary Effusion: A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. It is associated with HUMAN HERPESVIRUS 8, most often occurring in the setting of immunodeficiency.Adenoids: A collection of lymphoid nodules on the posterior wall and roof of the NASOPHARYNX.Ear Diseases: Pathological processes of the ear, the hearing, and the equilibrium system of the body.Amoxicillin: A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.Tympanoplasty: Surgical reconstruction of the hearing mechanism of the middle ear, with restoration of the drum membrane to protect the round window from sound pressure, and establishment of ossicular continuity between the tympanic membrane and the oval window. (Dorland, 28th ed.)Otoscopes: Instruments designed to inspect or auscultate the ear. They are designed primarily to examine the outer ear canal and tympanic membrane by means of light and air under moderate pressure, as with a pneumatic otoscope. (UMDNS, 1999)Mastoid: The posterior part of the temporal bone. It is a projection of the petrous bone.Hearing Loss: A general term for the complete or partial loss of the ability to hear from one or both ears.Respiratory Tract Infections: Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.Sulfisoxazole: A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.Diagnostic Techniques, Otological: Methods and procedures for the diagnosis of diseases of the ear or of hearing disorders or demonstration of hearing acuity or loss.Earache: Pain in the ear.Adenoidectomy: Excision of the adenoids. (Dorland, 28th ed)Recurrence: The return of a sign, symptom, or disease after a remission.Ear Canal: The narrow passage way that conducts the sound collected by the EAR AURICLE to the TYMPANIC MEMBRANE.Pericardiocentesis: Puncture and aspiration of fluid from the PERICARDIUM.Cardiac Tamponade: Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.Pneumococcal Vaccines: Vaccines or candidate vaccines used to prevent infections with STREPTOCOCCUS PNEUMONIAE.Neisseriaceae Infections: Infections with bacteria of the family NEISSERIACEAE.Anti-Bacterial Agents: Substances that reduce the growth or reproduction of BACTERIA.Pleura: The thin serous membrane enveloping the lungs (LUNG) and lining the THORACIC CAVITY. Pleura consist of two layers, the inner visceral pleura lying next to the pulmonary parenchyma and the outer parietal pleura. Between the two layers is the PLEURAL CAVITY which contains a thin film of liquid.Vaccines, Conjugate: Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Hearing Tests: Part of an ear examination that measures the ability of sound to reach the brain.Child Day Care Centers: Facilities which provide care for pre-school and school-age children.Empyema, Pleural: Suppurative inflammation of the pleural space.Sinusitis: Inflammation of the NASAL MUCOSA in one or more of the PARANASAL SINUSES.Subdural Effusion: Leakage and accumulation of CEREBROSPINAL FLUID in the subdural space which may be associated with an infectious process; CRANIOCEREBRAL TRAUMA; BRAIN NEOPLASMS; INTRACRANIAL HYPOTENSION; and other conditions.Azithromycin: A semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.Cefaclor: Semisynthetic, broad-spectrum antibiotic derivative of CEPHALEXIN.Mucous Membrane: An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.Hearing Loss, Conductive: Hearing loss due to interference with the mechanical reception or amplification of sound to the COCHLEA. The interference is in the outer or middle ear involving the EAR CANAL; TYMPANIC MEMBRANE; or EAR OSSICLES.Pleurodesis: The production of adhesions between the parietal and visceral pleura. The procedure is used in the treatment of bronchopleural fistulas, malignant pleural effusions, and pneumothorax and often involves instillation of chemicals or other agents into the pleural space causing, in effect, a pleuritis that seals the air leak. (From Fishman, Pulmonary Diseases, 2d ed, p2233 & Dorland, 27th ed)Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Audiometry: The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.Bacterial Infections: Infections by bacteria, general or unspecified.Xylitol: A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.Nasopharyngeal Diseases: Pathological processes involving the NASOPHARYNX.Ascitic Fluid: The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Mass Media: Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.Otologic Surgical Procedures: Surgery performed on the external, middle, or internal ear.Pleural Cavity: Paired but separate cavity within the THORACIC CAVITY. It consists of the space between the parietal and visceral PLEURA and normally contains a capillary layer of serous fluid that lubricates the pleural surfaces.Hydrothorax: A collection of watery fluid in the pleural cavity. (Dorland, 27th ed)Drainage: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.Myringoplasty: Surgical restoration of a perforated tympanic membrane by grafting. (Dorland, 28th ed.)Paracentesis: A procedure in which fluid is withdrawn from a body cavity or organ via a trocar and cannula, needle, or other hollow instrument.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Antibodies, Bacterial: Immunoglobulins produced in a response to BACTERIAL ANTIGENS.Pericarditis: Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.Ear Ossicles: A mobile chain of three small bones (INCUS; MALLEUS; STAPES) in the TYMPANIC CAVITY between the TYMPANIC MEMBRANE and the oval window on the wall of INNER EAR. Sound waves are converted to vibration by the tympanic membrane then transmitted via these ear ossicles to the inner ear.Streptolysins: Exotoxins produced by certain strains of streptococci, particularly those of group A (STREPTOCOCCUS PYOGENES), that cause HEMOLYSIS.Chylothorax: The presence of chyle in the thoracic cavity. (Dorland, 27th ed)Cefuroxime: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.Infant, Newborn: An infant during the first month after birth.Facial Paralysis: Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis.Haemophilus Vaccines: Vaccines or candidate vaccines containing antigenic polysaccharides from Haemophilus influenzae and designed to prevent infection. The vaccine can contain the polysaccharides alone or more frequently polysaccharides conjugated to carrier molecules. It is also seen as a combined vaccine with diphtheria-tetanus-pertussis vaccine.Human bocavirus: A member of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, originally isolated from human nasopharyngeal aspirates in patients with respiratory disease.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Cerumen: The yellow or brown waxy secretions produced by vestigial apocrine sweat glands in the external ear canal.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Herpesvirus 8, Human: A species in the genus RHADINOVIRUS, subfamily GAMMAHERPESVIRINAE, isolated from patients with AIDS-related and "classical" Kaposi sarcoma.Culture Media, Conditioned: Culture media containing biologically active components obtained from previously cultured cells or tissues that have released into the media substances affecting certain cell functions (e.g., growth, lysis).Ascites: Accumulation or retention of free fluid within the peritoneal cavity.

Middle ear fluid cytokine and inflammatory cell kinetics in the chinchilla otitis media model. (1/256)

Streptococcus pneumoniae is the most frequent microbe causing middle ear infection. The pathophysiology of pneumococcal otitis media has been characterized by measurement of local inflammatory mediators such as inflammatory cells, lysozyme, oxidative metabolic products, and inflammatory cytokines. The role of cytokines in bacterial infection has been elucidated with animal models, and interleukin (IL)-1beta, IL-6, and IL-8 and tumor necrosis factor alpha (TNF-alpha) are recognized as being important local mediators in acute inflammation. We characterized middle ear inflammatory responses in the chinchilla otitis media model after injecting a very small number of viable pneumococci into the middle ear, similar to the natural course of infection. Middle ear fluid (MEF) concentrations of IL-1beta, IL-6, IL-8, and TNF-alpha were measured by using anti-human cytokine enzyme-linked immunosorbent assay reagents. IL-1beta showed the earliest peak, at 6 h after inoculation, whereas IL-6, IL-8, and TNF-alpha concentrations were increasing 72 h after pneumococcal inoculation. IL-6, IL-8, and TNF-alpha but not IL-1beta concentrations correlated significantly with total inflammatory cell numbers in MEF, and all four cytokines correlated significantly with MEF neutrophil concentration. Several intercytokine correlations were significant. Cytokines, therefore, participate in the early middle ear inflammatory response to S. pneumoniae.  (+info)

Pneumococcus activation of the 5-lipoxygenase pathway and production of glycoproteins in the middle ear of rats. (2/256)

Pneumococcal otitis media is associated with the production of potent inflammatory mediators (leukotrienes), but the mechanism by which pneumococcus induces production of leukotrienes in the middle ear is poorly understood. In this study, up-regulation of 2 genes that govern the lipoxygenase pathway, cPLA2 and 5-LOX, was observed in rats following inoculation of pneumococcus into the middle ear cavity. Expression of cPLA2 was low, and 5-LOX gene expression was not detected in control animals. Up-regulation of cPLA2 and 5-LOX in middle ear epithelial cells was accompanied by an increase of high-molecular-weight glycoproteins in middle ear fluid and cells. These findings suggest that pneumococcus activates the lipoxygenase pathway by up-regulating expression of the cPLA2 and 5-LOX genes. This, in turn, may stimulate synthesis and secretion of high-molecular-weight glycoproteins that facilitate production of fluid in the middle ear cleft.  (+info)

Interpretation of middle ear fluid concentrations of antibiotics: comparison between ceftibuten, cefixime and azithromycin. (3/256)

AIMS: The aim of this study was to determine the potential influence of variables such as the cell content in the fluid, and serum levels, on the concentrations of ceftibuten, cefixime and azithromycin in the middle ear fluid of patients suffering from acute otitis media. METHODS: This randomized, open study compared the penetration of ceftibuten (9 mg kg(-1) 18 patients), cefixime (8 mg kg(-1), 16 patients) and azithromycin (10 mg kg(-1) 16 patients) into the intracellular and extracellular compartments of middle ear fluid of 50 paediatric patients (aged 8-14 years) with acute otitis media. Middle ear fluid was extracted by tympanocentesis 4, 12 and 24 h after dosing and divided into two fractions: with cells (as collected) (C+) and cell-free (C-). Antibiotics were assayed in C+ and C- samples by h.p.l.c. RESULTS: Ceftibuten achieved greater penetration into middle ear fluid than cefixime and azithromycin. Higher concentrations of ceftibuten (CTB) and cefixime (CFX) were found in the C- fraction (CTB: 4h 13.3+/-1.86; 12h 4.7+/-1.18; 24h 0.5+/-0.2. CFX: 4h 3.2+/-1.4; 12h 1.5+/-0.5; 24h>(0.1 mgl(-1)) than in the C+ fraction (CTB:4 h 8.4+/-4.3; 12 h 2.88+/-1.19; 24 h 0.3+/-0.27. CFX: 4 h 1.2+/-0.6; 12 h 0.8+/-0.2; 24 h>0.1 mg l(-1)) at the each time point, while the opposite was true for azithromycin (C-: 4 h 0.11+/-0.04; 12 h 0.12+/-0.08; 24 h 0.23+/-0.12. C+: 4 h 0.38+/-0.24; 12 h 0.9+/-0.03; 24 h 1.05+/-0.3 mg l(-1)). CONCLUSIONS: This study demonstrates that the penetration of antibiotics into the middle ear fluid is influenced by its serum concentrations as well as by the cell content in the fluid. Ceftibuten achieved higher middle ear fluid concentrations than cefixime in C+ and C- fractions at all time points. Both ceftibuten and cefixime concentrations are negatively influenced by the cell content in the fluid. In contrast the concentration of azithromycin to the middle ear fluid is positively influenced by the cell content in the fluid.  (+info)

Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection. (4/256)

Three separate studies, two involving active-immunization regimens and one involving a passive-transfer protocol, were conducted to initially screen and ultimately more fully assess several nontypeable Haemophilus influenzae outer membrane proteins or their derivatives for their relative protective efficacy in chinchilla models of otitis media. Initial screening of these antigens (P5-fimbrin, lipoprotein D, and P6), delivered singly or in combination with either Freund's adjuvant or alum, indicated that augmented bacterial clearance from the nasopharynx, the middle ears, or both anatomical sites could be induced by parenteral immunization with P5-fimbrin combined with lipoprotein D, lipoprotein D alone, or the synthetic chimeric peptide LB1 (derived from P5-fimbrin), respectively. Data from a second study, wherein chinchillas were immunized with LB1 or lipoprotein D, each delivered with alum, again indicated that clearance of nontypeable H. influenzae could be augmented by immunization with either of these immunogens; however, when this adjuvant was used, both antibody titers in serum and efficacy were reduced. A third study was performed to investigate passive delivery of antisera directed against either LB1, lipoprotein D, nonacylated lipoprotein D, or a unique recombinant peptide designated LPD-LB1(f)2,1,3. The last three antiserum pools were generated by using the combined adjuvant of alum plus monophosphoryl lipid A. Passive transfer of sera specific for LB1 or LPD-LB1(f)2,1,3 to adenovirus-compromised chinchillas, prior to intranasal challenge with nontypeable H. influenzae, significantly reduced the severity of signs and incidence of otitis media which developed (P +info)

Complement activation and expression of membrane regulators in the middle ear mucosa in otitis media with effusion. (5/256)

The aetiopathogenesis of chronic otitis media with effusion (OME) in children is not yet fully understood. OME is characterized by metaplasia of the epithelium and accumulation of sticky, glue-like effusion in the middle ear containing different mediators of inflammation, including activation fragments of the complement system. Here we examined whether the fluid phase complement activation is reflected in the middle ear mucosa and how the mucosa is protected against the cytolytic activity of complement. Mucosal biopsies from 18 middle ears of children with a history of chronic OME were taken. The biopsies were analysed by immunofluorescence microscopy after staining for complement fragments iC3b/C3c, C3d and C9, and regulators membrane cofactor protein (MCP; CD46), decay-accelerating factor (DAF; CD55) and protectin (CD59). There was a strong staining for iC3b/C3c, and a weaker one for C3d and C9 on the surface of the middle ear epithelial cells of OME patients but not in controls without OME. MCP was expressed on the hyperplastic three to four outer cell layers of the epithelium, while CD59 was expressed throughout the middle ear mucosa. The results suggest a strong ongoing complement activation and consequent inflammation in the middle ear cavity. Unrestricted complement damage of the epithelial lining is prevented by the strong expression of MCP and CD59.  (+info)

Accumulation of factors influencing children's middle ear disease: risk factor modelling on a large population cohort. (6/256)

STUDY OBJECTIVES: Data were analysed from a large national birth cohort to examine cumulative and interactive prediction from various risk factors for childhood middle ear disease, and to resolve conflicting evidence arising from small and incompletely controlled studies. The large sample size permitted appropriate covariate adjustment to give generality, and permit demographic breakdown of the risk factors. SETTING: A large multi-purpose longitudinal birth cohort study of all births in the UK in one week in 1970, with multiple questionnaire sweeps. PARTICIPANTS: Over 13,000 children were entered into the original cohort. Data on over 12,000 children were available at the five year follow up. MAIN OUTCOME MEASURES: For children at 5 years, parent reported data were available on health and social factors including data on two markers for middle ear disease: the occurrence of purulent (nonwax) ear discharge and suspected or confirmed hearing difficulty. MAIN RESULTS: In those children who had ever had reported hearing difficulty (suspected or confirmed), after control for socioeconomic status, three of the classic factors (male sex, mother's smoking habits since birth, and attending day care) were significantly more frequent. In those who had ever had ear discharge reported, only mother's smoking habit since birth was significantly more frequent. However, it showed an orderly dose response relation. In addition, a derived general child health score was found to be significantly associated with both the middle ear disease markers. Control for this variable in the analysis of those having reported hearing difficulty reduced the effect size of mother's smoking habit, but it remained statistically significant. For reported ear discharge, even after control for the general health score and social index, mother's smoking habits and day care attendance were both significant predictors. Mother's (but not father's) smoking habits and day care attendance were found to be significant risk factors for middle ear disease. Breast feeding effects were weak and did not generally survive statistical control. CONCLUSIONS: A child having all three risk factors (attends day care, a mother who smokes, and male sex) is 3.4 times more likely to have problems with hearing than a child who has none, based on cumulative risk. Further studies should focus on preventative risk modification and well specified intervention.  (+info)

Antimicrobial treatment of an experimental otitis media caused by a beta-lactamase positive isolate of Haemophilus influenzae. (7/256)

A gerbil model of otitis media induced by a beta-lactamase producing and non-serotypeable isolate of Haemophilus influenzae was used to assess the in-vivo efficacy of co-amoxiclav and cefuroxime at low (5 mg/kg) and high (20 mg/kg) doses. The MIC of the antibiotics tested against the pathogen was 1 mg/L (1/0.5 mg/L for co-amoxiclav). The organism was inoculated (+/-10(6) cfu) by transbullar challenge directly in the middle ear and antibiotic treatment was commenced 2 h post-inoculation and continued at 8 h intervals for three doses. Only high dose co-amoxiclav significantly reduced the number of culture-positive specimens as compared with untreated animals or with other treatment groups (91.7% as compared with 36.7% for high dose cefuroxime). The results obtained in any treatment group were related to middle ear antibiotic level/MIC. Antibiotic concentrations in the middle ear 90 min after administration were about 10% of serum levels at 15 min, probably related to a slight inflammatory response. Only after high dose co-amoxiclav did the concentration in the middle ear exceed the MIC by a factor of four. In otitis media with effusion, if indicated, antibiotics active in vitro should be administered in high doses and, to avoid side effects, probably in short courses.  (+info)

Middle ear effusion: rate and risk factors in Australian children attending day care. (8/256)

There have been no previous longitudinal studies of otitis media conducted in non-Aboriginal Australian children. This paper describes the rate and risk factors for middle ear effusion (MEE) in children attending day care in Darwin, Australia. A prospective cohort study of 252 children under 4 years was conducted in 9 day care centres over 12 fortnights between 24 March and 15 September 1997. Tympanometry was conducted fortnightly and multivariate analysis used to determine risk factors predicting MEE. The outcome of interest was the rate of type B tympanograms per child detected in either ear at fortnightly examinations. After adjusting for clustering by child, MEE was detected on average 4.4 times in 12 fortnights (37% of all examinations conducted). Risk factors associated with presence of effusion were younger age, a family history of ear infection, previous grommets (tympanostomy tubes), ethnicity and the day care centre attended. A history of wheeze appeared protective. These effects were modest (RR 0.57-1.70). Middle ear effusion is very common in children attending day care in Darwin. This has clinical importance, since MEE during early childhood may affect optimal hearing, learning and speech development. There is little scope for modification for many of the risk factors for MEE predicted by this model. Further study of the day care environment is warranted.  (+info)

Characterization of human middle ear mucus glycoprotein in chronic secretory otitis media (CSOM). - Semantic ScholarCharacterization of human middle ear mucus glycoprotein in chronic secretory otitis media (CSOM). - Semantic Scholar
Middle ear effusion was obtained from children with chronic secretory otitis media undergoing myringotomy. The effusions contained about 120 mg/ml non-dialysable solids, of which 18-31% was mucus glycoprotein. The purified mucus glycoprotein had a composition characteristic of other mucus glycoproteins. Amino acid analysis of the glycoprotein indicates a protein core consisting of glycosylated regions resistant to proteolysis and non-glycosylated regions susceptible to proteolysis. Analysis of the mucus glycoprotein by gel filtration on Sepharose 2B showed that reduction caused a decrease in hydrodynamic size and proteolysis caused a further decrease. The difference was confirmed by sedimentation coefficient and viscosity measurements. The reduced glycoprotein had an intrinsic viscosity of 0.113 ml/mg and an S0(20) of 15.2S compared to a value of 0.018 ml/mg and 9.6S for the proteolytically digested glycoprotein. These results suggest a model for this middle ear mucus glycoprotein, in which the native
Penetration of erythromycin through respiratory mucosa : a study using secretory otitis media as a model (Book, 1979) [WorldCat...Penetration of erythromycin through respiratory mucosa : a study using secretory otitis media as a model (Book, 1979) [WorldCat...
Get this from a library! Penetration of erythromycin through respiratory mucosa : a study using secretory otitis media as a model. [L Sundberg;]
Complement in Chronic Secretory Otitis Media | JAMA Otolaryngology-Head & Neck Surgery | The JAMA NetworkComplement in Chronic Secretory Otitis Media | JAMA Otolaryngology-Head & Neck Surgery | The JAMA Network
• Occurrence of in vivo C3 breakdown and in vitro C3 splitting activity was studied in serum and middle-ear effusion (MEE) samples from 30 children with chronic
Review: parental smoking increases risk of recurrent otitis media, middle ear effusion, and tonsillectomy or adenoidectomy in...Review: parental smoking increases risk of recurrent otitis media, middle ear effusion, and tonsillectomy or adenoidectomy in...
There are increasing public health concerns about the effects of passive tobacco smoke exposure. Clinical research is providing evidence that children who inhale secondhand smoke may have a higher incidence of health problems such as upper respiratory infections, otitis media, tonsillitis, aggravation of chronic respiratory conditions, and sudden infant death syndrome.1. The meta-analysis by Strachan and Cook clearly confirms the effect of environmental tobacco exposure on young childrens risk of developing middle ear problems. This is consistent with a previous meta-analysis which concluded that use of tobacco products by adults increased childhood mortality and morbidity.2. The authors chose to include only published studies in their review. This exclusion could affect the conclusions of the review because of the potential for "publication bias" (ie, studies that are published are more likely to report statistically significant findings than are studies that are not accepted or submitted for ...
Glue EarGlue Ear
What is glue ear?. Glue ear is a condition where there is a build up of fluid in the middle ear. Other names for it include serous or secretory otitis media (SOM), otitis media with effusion (OME), catarrhal or non-suppurative otitis media.. How common is it?. It is the commonest cause of hearing loss in childhood, with up to 50% of all children having an episode at some stage. The prevalence, that is the number of affected individuals at a particular point in time, depends on age but in children aged 2 to 7 years of age is about 20%.. What is the middle ear?. The ear consists of three parts. The outer ear includes the pinna ( the floppy part attached to the side of the head) and the outer ear canal. The middle ear is the space between the eardrum and the inner ear. It contains the three little bones of hearing, the ossicles. Sound energy comes down the ear canal and vibrates the eardrum which then vibrates the bones of hearing, and in this manner the sound energy is transmitted to the inner ...
Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.
In a series of 163 ears with chronic, mucoid effusion, free or immune complex bound pneumococcal capsular polysaccharide antigens were demonstrated with Omniserum and counterimmunoelectrophoresis (CIEP) in 37 ears (23%). In crushed adenoid tissue thi
Secretory Otitis Media in Children - Childrens Health Issues - Merck Manuals Consumer VersionSecretory Otitis Media in Children - Children's Health Issues - Merck Manuals Consumer Version
Learn about the causes, symptoms, diagnosis & treatment of Ear, Nose, and Throat Disorders in Children from the Home Version of the Merck Manuals.
Effect of recolonisation with interfering α streptococci on recurrences of acute and secretory otitis media in children:...Effect of recolonisation with "interfering" α streptococci on recurrences of acute and secretory otitis media in children:...
PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
Rheologic Studies on Middle Ear Effusions and Their Mucus Glycoproteins | JAMA Otolaryngology-Head & Neck Surgery | The JAMA...Rheologic Studies on Middle Ear Effusions and Their Mucus Glycoproteins | JAMA Otolaryngology-Head & Neck Surgery | The JAMA...
• The properties of pooled thick and thin middle ear effusions, from children with otitis media with effusion, were studied by viscometry. Mucus glycoproteins w
Middle Ear Effusion in Intensive Care Unit Patients at Al-Sadder Teaching Hospital in Al-Najaf City-Iraq (A Prospective...Middle Ear Effusion in Intensive Care Unit Patients at Al-Sadder Teaching Hospital in Al-Najaf City-Iraq (A Prospective...
Middle Ear Effusion in Intensive Care Unit Patients at Al-Sadder Teaching Hospital in Al-Najaf City-Iraq (A Prospective Randomized Comparative Clinical Study)
About GH: Whos Who in Port Charles | Jeff Webber | General HospitalAbout GH: Who's Who in Port Charles | Jeff Webber | General Hospital
Jeff Webber was first introduced in the spring of 1976 when he arrived in Port Charles after graduating from medical school. Jeff and his wife Monica Bard Webber planned to join the staff of General Hospital following in the footsteps of Jeffs older brother Rick who had joined GH two months before but had recently been killed in a plane crash over Africa. Steve Hardy tapped the young married Webbers for a bold new experimental program at the hospital called Mr. and Mrs. Intern. For Steve, the Mr. and Mrs. Intern experiment was a noble gamble. He believed that Jeff and Monica were a perfect choice. It was six months into their marriage and Steve assumed they were ideally happy. Steve was wrong. Their marriage was a wreck. Jeff had a major hang up. Jeff feared everyone at GH was comparing him to his dead brother Rick. Fearing he would always be second best, Jeffs every thought was plagued by memories of Rick. Jeff missed him dearly...and so did Monica. Before Monica married Jeff, she had once ...
Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance - Full Text View...Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance - Full Text View...
Proportion of children initially diagnosed with AOM who experience treatment failure at or before the day 12-14 visit.. TF is defined as substantial persistence or worsening of symptoms specifically attributable to AOM, or of otoscopic signs of AOM, after 72 hours from the time of randomization, such that additional antimicrobial therapy is deemed advisable. If a parent/legal guardian is unwilling to continue the assigned study product regimen, the participant will be categorized as TF. Should a participant be administered another systemic antibiotic while taking study medication or prior to Day 16, the participant will be considered a TF. Clinical success is defined as complete or substantial resolution of symptoms specifically attributable to AOM for 48 hours and of otoscopic signs of acute inflammation (bulging of the tympanic membrane (TM) or intense erythema), with or without persistence of middle-ear effusion, such that no additional antibiotic therapy is deemed advisable. ...
Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance - Full Text View...Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance - Full Text View...
Proportion of children initially diagnosed with AOM who experience treatment failure at or before the day 12-14 visit.. TF is defined as substantial persistence or worsening of symptoms specifically attributable to AOM, or of otoscopic signs of AOM, after 72 hours from the time of randomization, such that additional antimicrobial therapy is deemed advisable. If a parent/legal guardian is unwilling to continue the assigned study product regimen, the participant will be categorized as TF. Should a participant be administered another systemic antibiotic while taking study medication or prior to Day 16, the participant will be considered a TF. Clinical success is defined as complete or substantial resolution of symptoms specifically attributable to AOM for 48 hours and of otoscopic signs of acute inflammation (bulging of the tympanic membrane (TM) or intense erythema), with or without persistence of middle-ear effusion, such that no additional antibiotic therapy is deemed advisable. ...
Jeff Garcia breaks down Colin Kaepernick | Inside the 49ersJeff Garcia breaks down Colin Kaepernick | Inside the 49ers
This requires a response. No, I for one will not call Jeff a racist at all. However, just by your name I have always assumed you had those inclinations.. I sure am glad you admitted what you are, and I could not have said it better myself. -A hack, along with uninformed, ignorant and a Colon Hater. Still doing the name calling, That is the definition of a hater. Jeff is none of those. While I disagree with his assessment, I think he has been one of the best QBs after Joe and Steve.. To some of the ignorant and uninformed, I will try to set the record straight. Jeff Garcia said some pretty harsh things about Kaep, I will not elaborate, but it is all in the archives. For that reason, Kaep chose Warner over Jeff. Jeff cannot burn bridges and expect different treatment. Jeff got so desperate, he was begging in a wheedling tone, but it was too late. Many wondered why Kaep chose Warner over Jeff. Kaep explained it as not needing the mobility coaching, he wanted to work on his weaknesses, and Warner ...
Slayers Kerry King on Relationship with Jeff Hanneman: I Dont Think We Were Ever Best FriendsSlayer's Kerry King on Relationship with Jeff Hanneman: I Don't Think We Were Ever Best Friends
Any time we would finish a tour, Jeff] would just go home and detach, King tells Guitar World. He might have lived only 45 minutes away, but unless you were part of his inner circle, it was hard to stay in touch with him. And it took me a few years to understand that. For a while I was just like, Why isnt this guy calling me back? But as I got older, I just realized that that was who Jeff was.. I dont think Jeff and I were ever best friends, continues King. I think we were probably the closest in the band, but never best friends. To put it in a way that everyone could understand, Jeff and I were like business partners. Was he my friend? Of course he was my friend. But we didnt really act like that. The last time I was at Jeffs house was January 2003. We went to his place to watch the Raiders in the playoffs. And it sounds horrible, but it wasnt horrible. That was just how it was.. ...
Jeff Healey releases Holding On - Maxazine.comJeff Healey releases 'Holding On' - Maxazine.com
Nobody embodies the defiant spirit of rock and blues quite like Jeff Healey. Born in Toronto on March 25th, 1966, the Canadians childhood was shattered by diagnosis with the rare ocular cancer retinoblastoma. Yet it never broke his stride, and through the late-80s, 90s and post-millennium, Jeffs jaw-dropping guitar style and soul-drenched vocals saw him rise to multi-platinum sales, worldwide acclaim and collaborations with the likes of Stevie Ray Vaughan, B.B. King, John Mayall, Eric Clapton, The Rolling Stones, Lenny Kravitz, George Harrison, Mark Knopfler and Ian Gillan.. Since his untimely passing in March of 2008, Jeffs Estate has worked diligently to ensure that his memory and incredible legacy would continue to shine on.. Released in March of 2016 on what would have been the his 50th birthday, Heal My Soul is a lost album comprising twelve previously unheard tracks, all rescued from the vaults, lovingly restored by the guitarists estate and alive with his spirit. "I think Jeff ...
Facial Numbness? | Tinnitus Talk Support ForumFacial Numbness? | Tinnitus Talk Support Forum
Hello folks. I have had tinnitus in my left ear since April this year when I had middle ear effusion. Now, in August I am also having facial numbness...
Whenever she greeted him with an extended hug and kissed their ear Jeff knew this will be an incredible evening. - Prime CargosWhenever she greeted him with an extended hug and kissed their ear Jeff knew this will be an incredible evening. - Prime Cargos
The after scene ended up being after dinner, they arrived towards the living room and she asked her spouse to place a cd on and shes going to be directly right straight back ina moment. Whenever she came ultimately back in a gown this is certainly quick watch out of robe a X rated online video wound up being playing. She sat about the settee and asked them to be detailed they very nearly dropped straight down getting there on her. The film was indeed a female, in addition to 2 men, considered one of that is black colored colored. The woman finished up being naked and was pulling the mens underwear down. The mans which can be black colored finished up being huge whenever soft, since big as Bobs hard, in addition to the other mans the length of Bobs. She began to draw the blacks cock plus it became long and hard. The partner asked Jeff if it had been proper that many mens which are black colored was in fact huge. Jeff reacted the trend is see all on your own, and she did and Jeffs had been ...
SONS OF THE DOLLS: JEFF HILLSONS OF THE DOLLS: JEFF HILL
En provenance du Jeff Hill Band , Jeff Hill est signé en 1977 par Chiswick (label qui , faut-il le rappeler , fit les beaux jours du punk anglais avec Stiff ) qui préfère miser sur un artiste solo que sur un groupe ! Joli flop pour un bon single pourtant ! Jeff sortira un autre 45t sans rencontrer plus de succès ! ...
3x22 Introduction to Finality (Coming Full Circle)3x22 "Introduction to Finality" (Coming Full Circle)
When Alan confronts Jeff and insists that he throw the case in order to return to his former life, theres this definite sense of coming full circle from the person Jeff was three years ago. Back then, his only goal was to get out of Greendale and return to normal. And he wanted to do so as unscathed as possible (his conversations with Duncan reflect that). But now, Jeff is presented once again with a choice - he can throw the case that his friend is fighting for and go back to the life he wanted after Greendale or… he can choose not to do that. But make sure you realize that Jeff DOES have a choice, and what he chooses during this episode defines him more than any other choice he has made thus far. Shirleys response does too, in fact. She must overhear the conversation between Alan and Jeff (or otherwise Jeff tells her), because she tells him to drop her case -- she doesnt want Jeff running into trouble when he returns to his old firm. And, she says, "I want you to have what you want." And ...
PATCH 1/5] t4015: refactor --color-moved whitespace test - Jeff KingPATCH 1/5] t4015: refactor --color-moved whitespace test - Jeff King
From: Jeff King ,[email protected], To: Junio C Hamano ,[email protected], Cc: Stefan Beller ,[email protected],, [email protected], [email protected] Subject: [PATCH 1/5] t4015: refactor --color-moved whitespace test Date: Thu, 19 Oct 2017 16:24:03 -0400 Message-ID: ,[email protected], (raw) In-Reply-To: ,[email protected], In preparation for testing several different whitespace options, lets split out the setup and cleanup steps of the whitespace test. While were here, lets also switch to using ,,- to indent our here-documents properly, and use q_to_tab to more explicitly mark where we expect whitespace to appear. Signed-off-by: Jeff King ,[email protected], --- t/t4015-diff-whitespace.sh , 49 +++++++++++++++++++++++++++------------------- 1 file changed, 29 insertions(+), 20 deletions(-) diff --git a/t/t4015-diff-whitespace.sh b/t/t4015-diff-whitespace.sh index 87083f728f..164b502405 100755 --- a/t/t4015-diff-whitespace.sh ...
Jeff Davis Hospital in Hazlehurst, GAJeff Davis Hospital in Hazlehurst, GA
Jeff Davis Hospital of Hazlehurst, GA ratings and quality report. Compare Jeff Davis Hospital to other nearby hospitals in Georgia.
Yankee Pot Roast: Barnosky, JeffYankee Pot Roast: Barnosky, Jeff
During his first year of school, Jeff Barnosky believed that each of his teachers was Bea Arthur in disguise. Especially Mr. Roberts. He lives in Philadelphia, he dies in Cleveland and he questions the true nature of all existence in Toronto. Hes been published in McSweeneys, Pindeldyboz, Exquisite Corpse, and the late, much missed Haypenny.. Permanently hyperlinked via http://www.yankeepotroast.org/archives/2003/02/jeff_barnosky.html. ...
Mentice, Inc. Expands Its North American Sales and Clinical Presence With the Hiring of Jeff Sirek as Director of Educational...Mentice, Inc. Expands Its North American Sales and Clinical Presence With the Hiring of Jeff Sirek as Director of Educational...
Health,... EVANSTON Ill. April 25 /- Mentice Inc. (a wholly ...Jeff Sirek joins Mentice after five top performing and highlysuccessf...Mr. Sirek will be tasked with driving the educational/hospital market...Sue Landsman brings to Mentice a wealth of experience in a broad range...,Mentice,,Inc.,Expands,Its,North,American,Sales,and,Clinical,Presence,With,the,Hiring,of,Jeff,Sirek,as,Director,of,Educational,Sales-East,and,Sue,Landsman,as,Clinical,Applications,Manager,for,the,Americas.,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
Jeff Lewis Color 1-gal. #JLC214 Quarry Quarter-Gloss Ultra-Low VOC Interior Paint-301214 - The Home DepotJeff Lewis Color 1-gal. #JLC214 Quarry Quarter-Gloss Ultra-Low VOC Interior Paint-301214 - The Home Depot
Jeff Lewis Color is a premium, ultra-low VOC interior paint that delivers excellent hiding qualities and durability. Created by renowned designer Jeff Lewis, the palette simplifies the process of painting
Top Finance Expert in Houston, TX: Jeff Anapolsky | ToptalTop Finance Expert in Houston, TX: Jeff Anapolsky | Toptal
Jeff is a freelance Finance Expert based in Houston, TX, United States with over 10 years of experience. Learn more about Jeffs portfolio.
TV Guide - Slayer Guitarist Jeff Hanneman Dies at 49 - News - The Sun-Times - Heber Springs, AR - Heber Springs, ARTV Guide - Slayer Guitarist Jeff Hanneman Dies at 49 - News - The Sun-Times - Heber Springs, AR - Heber Springs, AR
Jeff Hanneman, the guitarist for Slayer since 1981, died Thursday of liver failure. He was 49.Remember other celebs weve lost this yearSlayer is devastated to inform that their bandmate and brother, Jeff Hanneman, passed away at about 11 a.m. this ...
Interview with Jeff Wampler, CTO of Netrix, LLC - Netrix LLCInterview with Jeff Wampler, CTO of Netrix, LLC - Netrix LLC
Today we caught up with Jeff Wampler, CTO of Netrix LLC to get insight into his journey at Netrix. Jeff has been the CTO and a Partner at Netrix since 2006
Pearls of Promise | Helping Women Overcome Lifes Trials | Page 189Pearls of Promise | Helping Women Overcome Life's Trials | Page 189
On Wednesday night, we had a scare that Ive had a hard time shaking. My husband Jeff came home from work a little under the weather but it was our tennis night with our friend Richard so he was trying to rally. Jeff thought it was just food poisoning though and after purging, he felt a lot better and thought he could play. I didnt think it was wise but he said he insisted that he felt fine, so we proceeded to play.. However, after a few games, Jeff began to feel bad again and had to sit down. He told Richard and me to go ahead and hit without him, but as we walked onto the court, we heard this snoring sound coming from Jeff. At first I thought he was joking, acting like he was bored with us but we immediately realized that he had passed out. His eyes were rolled back and there were other things going on, that I will not share. Needless to say, it was a scary scene! We brought Jeff upright and then I hurriedly called 9-1-1. I realized I do not react well under pressure because I was unable to ...
A Weekend in Phoenix (With a Health Scare) | Running in MuckA Weekend in Phoenix (With a Health Scare) | Running in Muck
Once Jeff got in the water, SheriAnne, two of her kids, Jerry, and I went to the hospitality tent for some breakfast. Jeff hoped to complete the swim in 1:40. At about 1:15, we all walked over to the bike area, where we could watch cyclists start their 112 miles, AND see swimmers enter the transition area. It was colder now, a little windy, and threatened to rain. We cheered on the cyclists and chatted happily, waiting to see Jeff running to transition. Once his "planned" finish time past, we started getting nervous. Ironman allows 2:20 to complete the swim or you get your timing chip taken from you, and you are listed as a DNF. (Did not finish) I couldnt believe we hadnt seen Jeff at the 2:00 mark. By 2:10, I ran to see if his bike was still in the transition area, thinking we might have missed him. Sadly, it was still there. My heart sank. How was this possible? A few more minutes and the cut off time passed. Jeff didnt make it. Now I was worried. We all were. We went over to the swim exit ...
racing | Running in Muckracing | Running in Muck
Once Jeff got in the water, SheriAnne, two of her kids, Jerry, and I went to the hospitality tent for some breakfast. Jeff hoped to complete the swim in 1:40. At about 1:15, we all walked over to the bike area, where we could watch cyclists start their 112 miles, AND see swimmers enter the transition area. It was colder now, a little windy, and threatened to rain. We cheered on the cyclists and chatted happily, waiting to see Jeff running to transition. Once his "planned" finish time past, we started getting nervous. Ironman allows 2:20 to complete the swim or you get your timing chip taken from you, and you are listed as a DNF. (Did not finish) I couldnt believe we hadnt seen Jeff at the 2:00 mark. By 2:10, I ran to see if his bike was still in the transition area, thinking we might have missed him. Sadly, it was still there. My heart sank. How was this possible? A few more minutes and the cut off time passed. Jeff didnt make it. Now I was worried. We all were. We went over to the swim exit ...
Z-LE(OMe)VD(OMe)-FMK | Abcam中国Z-LE(OMe)VD(OMe)-FMK | Abcam中国
购买Z-LE(OMe)VD(OMe)-FMK，具有细胞渗透性的Z-LEVD-FMK caspase-4抑制剂 derivative。使用Abcam高品质的Z-LE(OMe)VD(OMe)-FMK帮助您更快取得科研成果。
Jeff Kwatinetz Navigates to L.A.s Venice Canals (EXCLUSIVE) - VarietyJeff Kwatinetz Navigates to L.A.'s Venice Canals (EXCLUSIVE) - Variety
Late last summer, amid much hubbub and industry side-eye, Jeff Kwatinetz relaunched the Firm - a media production and talent management concern he co-founded in 1997 that quickly folded after he left in 2008 - and the occasionally polarizing showbiz veteran soon celebrated with the $4.
Jeff Desjarlais - Concord, MA - Counseling | Healthgrades.comJeff Desjarlais - Concord, MA - Counseling | Healthgrades.com
Visit Healthgrades for information on Jeff Desjarlais Find Phone & Address information, medical practice history, affiliated hospitals and more.
Watch Jeff and Gage Get Therapy For Their Baby | Flipping Out VideosWatch Jeff and Gage Get Therapy For Their Baby | Flipping Out Videos
Season 9 Episode 9 Show Highlight: With a baby on the way, Jeff Lewis and Gage Edward have a difficult (and kind of adorable) talk before their lives change forever.
Jeff Young D.V.M. - We All Deserve BetterJeff Young D.V.M. - We All Deserve Better
You never know by looking at someone what road they may be traveling on... The following is from an interview in Cure Magazine - 27 November 2018 Article written by Katie Kosko Jeff Young D.V.M.
Jeff Goldblum visits SF Levis HQ in new Disney+ show The World According to Jeff Goldblum - SFGateJeff Goldblum visits SF Levi's HQ in new Disney+ show 'The World According to Jeff Goldblum' - SFGate
Bart Sights, Levis vice president of tech innovation, tours Goldblum around the "experimental denim playground" that creates 3,000 different styles of jeans each season. Sights shows off their tablet creation application that features an staggering library of distress marks and patterns. The jeans used to be distressed in factories by hand, but now the Innovation Lab features a laser system that adds fade marks and burns holes in the denim itself. Naturally, Goldblum has a custom pair made with a leopard print pattern.. ...
The Ultimate Cheapskates Road Map to True Riches: A Practical (and Fun) Guide to Enjoying Life More by Spending Less by Jeff...The Ultimate Cheapskate's Road Map to True Riches: A Practical (and Fun) Guide to Enjoying Life More by Spending Less by Jeff...
The Paperback of the The Ultimate Cheapskates Road Map to True Riches: A Practical (and Fun) Guide to Enjoying Life More by Spending Less by Jeff Yeager
9780439706391: Great Cow Race (BONE #2) - AbeBooks - Jeff Smith: 04397063949780439706391: Great Cow Race (BONE #2) - AbeBooks - Jeff Smith: 0439706394
AbeBooks.com: Great Cow Race (BONE #2) (9780439706391) by Jeff Smith and a great selection of similar New, Used and Collectible Books available now at great prices.
PotshotsPotshots
I did think, however, that we could potentially face a problem from members of the public who notice that Jeff isnt actually laying out any kind of strategy to correct the problems of the nation, so I came up with, if you dont mind me saying so myself, an astoundingly brilliant gimmick. See, we all know that BN has shitloads of money to throw at campaigns, whereas the opposition are all a bunch of paupers living out of prime bungalows in USJ, right? So why not start a donation drive, with a target amount that Jeff claims to want to raise for his campaign? Basically, with a high-yet-feasible amount (after careful calculations I elected to go with RM100,000), people will be distracted into thinking that Jeffs campaign is actually fighting towards something tangible. We all know that for Malaysians the most tangible thing in the world is cash - oh so cold, oh so hard, and oh so tangible. This campaign fund idea has been a roaring success, with Jeff tagging a reminder about it onto each and every ...
Truthbomb Apologetics: Video: Street-Level Apologetics by Jeff DurbinTruthbomb Apologetics: Video: Street-Level Apologetics by Jeff Durbin
In this featured video, Pastor Jeff Durbin of Apologia Church in Tempe, AZ offers what may be the clearest introduction to pre-suppositional apologetics I have heard ...
AHMADS: Grease actor Jeff Conaway has diedAHMAD"S: 'Grease' actor Jeff Conaway has died
What happens is, like with most opiate addicts, eventually they take a little too much, not much more than usual, and they aspirate, so whats in their mouth gets into their lungs," Pinsky said. "That causes a rapidly progressing and overwhelming pneumonia that they usually dont know that they have, because theyre sort of too out of it because of the drugs and by the time they get to the hospital its too late. Thats what happened with Jeff." ...
David Price vs. Jeff Samardzija: Who Is MLBs Best Ace on the Block? | Bleacher ReportDavid Price vs. Jeff Samardzija: Who Is MLB's Best Ace on the Block? | Bleacher Report
Heres guessing that all general managers on the lookout for a stud starting pitcher this July would prefer to trade for David Price and Jeff Samardzija. But since thats not very practical, the best choice between the two would be...
Jeff Reifman | Author | Common DreamsJeff Reifman | Author | Common Dreams
Jeff Reifman articles and opinion pieces published by Common Dreams, a non-profit independent media outlet publishing since 1997 in Portland, Maine.
jeff goldblum - New York Magazinejeff goldblum - New York Magazine
See an archive of all jeff goldblum stories published on the New York Media network, which includes NYMag, The Cut, Vulture, and Grub Street.
Jeff Tittel | Author | Common DreamsJeff Tittel | Author | Common Dreams
Jeff Tittel articles and opinion pieces published by Common Dreams, a non-profit independent media outlet publishing since 1997 in Portland, Maine.
jeff zucker - New York Magazinejeff zucker - New York Magazine
See an archive of all jeff zucker stories published on the New York Media network, which includes NYMag, The Cut, Vulture, and Grub Street.
Blugrass Appoints Jeff Dunphy as CFO on Environmental XPRTBlugrass Appoints Jeff Dunphy as CFO on Environmental XPRT
CALGARY, AB -- (Marketwire) -- 06/10/10 -- Blugrass Energy, Inc. (OTCBB: BLUG) is pleased to announce that they have appointed Jeff Dunphy as the Chief ...
Taxi, Grease Star Jeff Conaway Dies At 60 « CBS Los...'Taxi,' 'Grease' Star Jeff Conaway Dies At 60 « CBS Los...
Jeff Conaway, who starred in the sitcom Taxi, played swaggering Kenickie in the movie musical Grease and publicly battled drug and alcohol addiction on Celebrity Rehab, died Friday.
Ventilation Tube - Ventilation Tube Manufacturers and Ventilation Tube SuppliersVentilation Tube - Ventilation Tube Manufacturers and Ventilation Tube Suppliers
ALL Manufacturer of Ventilation Tube for Ventilation Tube, China ventilation tube information resources . ventilation tube Marketplace In Taiwan ,China and Asian Manufacturers,Help you to find more Manufacturers,Suppliers,Exporter,Agent,Global ventilation tube buyers, ventilation tube,ventilation tube Factory.
Ventilation Tubes - Paediatric Advice Sheet - ENT CareVentilation Tubes - Paediatric Advice Sheet - ENT Care
Adult Advice Sheet click here). What are ventilation tubes? Ventilation tubes are very small plastic tubes, which sit in a hole in the eardrum. They let air get in and out of the ear. This keeps the ear healthy. Why do we use ventilation tubes? Some people get fluid behind the eardrum. This is sometimes called glue ear. It is very common in young children but it can happen in adults too. This can be due to the Eustachian tube (the passage between the ear and the back of the nose) not working properly and, in children, from enlarged adenoids. Most young children will have glue ear at some time but it doesnt always cause problems. We only need to treat it if it is causing problems with hearing or speech or if it is causing lots of ear infections. How long do ventilation tubes stay in for? Ventilation tubes fall out by themselves as the eardrum grows. They may stay in for six months, or a year, or sometimes even longer. You may not notice when they drop out. Does my child have to have ...
Water precautions for prevention of infection in children with ventilation tubes (grommets) | CochraneWater precautions for prevention of infection in children with ventilation tubes (grommets) | Cochrane
Review question Is there is any evidence to show that keeping ears dry after ventilation tube (grommet) insertion helps to prevent problems such as infections?. Background Ventilation tubes are used to treat hearing loss due to glue ear, or to treat recurrent ear infections. Most surgeons agree that childrens ears should be kept dry for a few weeks after the operation, but not all agree on whether ears need to be kept dry thereafter. Some surgeons will allow children to swim and bathe without ear protection, whereas others will recommend ears be kept dry while tubes are in place.. Study characteristics We included two studies, recruiting a total of 413 patients. One study looked at 201 children between six months and six years who had ventilation tubes inserted to treat glue ear or recurrent infections. Children were divided into two groups: one group was allowed to swim and bathe freely, the other group was instructed to wear ear plugs while swimming or bathing. Another study looked at 212 ...
Otitis Media (Ear Infection) - Health911.com - Ear InfectionsOtitis Media (Ear Infection) - Health911.com - Ear Infections
Causes and natural remedies for Otitis Media, including dietary changes, supplements and a comprehensive Wellness Program - Natural Remedies for Otitis Media, Otitis Media Treatment, Otitis Media in Children, Otitis Media Symptoms, Acute Otitis Media, Chronic Otitis Media, Otitis Media Probiotics, Adult Otitis Media, Pediatric Otitis Media,
Nasodren for Sinusitis Treatment: Usefulness of cyclamen in otitis mediaNasodren for Sinusitis Treatment: Usefulness of cyclamen in otitis media
In order to verify these effects of cyclamen extract in otitis media patients, it has been used in 33 patients with acute secretory otitis and 10 patients with chronic secretory otitis (32 were children aged 5-18 years and 11 were adults aged 20-77 years); in 28 cases, the main cause of the secretory otitis was the presence of an acute viral respiratory infection and in 17 it was rhinosinusitis. In the patients with acute secretory otitis, Nasodren® was administered once a day for 3 days; in the patients with chronic secretory otitis, it was administered for 5 days, starting on the second day after myringotomy. In addition, there was a control group with 30 patients (20 cases of acute otitis and 10 cases of chronic otitis ...
Middle Ear Fluid (Serous Otitis Media - Otitis Media With Effusion) VideoMiddle Ear Fluid (Serous Otitis Media - Otitis Media With Effusion) Video
Otitis Media With Effusion - Symptoms of Otitis Media With Effusion - Treatment of Otitis Media With Effusion - Serous Otitis Media - Middle Ear Fluid - OME - Secretory Otitis Media
The Otorhinolaryngologist - Management of Otitis Media with Effusion and Recurrent Acute Otitis MediaThe Otorhinolaryngologist - Management of Otitis Media with Effusion and Recurrent Acute Otitis Media
Abstract Otitis media with effusion (OME) and recurrent acute otitis media (RAOM) are both extremely common, with a significant impact on the childs and parents quality of life. Various treatment options have therefore been investigated to prevent their occurrence. A literature search was carried out on Medline, EMBASE and Cochrane database for relevant randomised controlled trials and meta-analyses. We sought to summarise the current evidence on the management of these common conditions.
Tympanostomy Tube Insertion - MedBroadcast.comTympanostomy Tube Insertion - MedBroadcast.com
A myringotomy with tympanostomy tube insertion is one of the most common surgical procedure for children. A myringotomy is a surgical procedure where a small incision is made in the eardrum (tympanic membrane), typically in both ears. Small plastic tubes (tympanostomy tubes), open at both ends, are then inserted into the incisions.
Identification of MUC5B Mucin Gene in Human Middle Ear With Chronic Otitis Media - Kawano - 2000 - The Laryngoscope - Wiley...Identification of MUC5B Mucin Gene in Human Middle Ear With Chronic Otitis Media - Kawano - 2000 - The Laryngoscope - Wiley...
Objectives To identify the mucin gene and its expressing cells in the middle ear mucosa with chronic otitis media (COM), and to study the correlation between infiltration of inflammatory cells in the submucosa and expression of the mucin gene in the mucosal epithelium with COM.. Study Design Middle ear mucosal specimens removed from the inferior promontory area of 19 patients undergoing middle ear surgery for COM were studied.. Methods Sections were stained with H&E, Alcian blue-periodic acid Schiff (AB-PAS), polyclonal MUC5B antibody, and specific MUC5B riboprobe for histological, histochemical, immunohistochemical, and mucin mRNA analyses.. Results H&E staining revealed pseudostratified epithelia in 18 of the middle ear specimens with COM and cuboidal secretory epithelia in one. AB-PAS staining of epithelia revealed abundant secretory cells and their products (glycoconjugates). In situ hybridization and immunohistochemistry studies demonstrated that the secretory cells of the middle ear mucosa ...
Control of chronic otitis media and sensorineural hearing loss in C3H/HeJ mice: Glucocorticoids vs mineralocorticoids<...Control of chronic otitis media and sensorineural hearing loss in C3H/HeJ mice: Glucocorticoids vs mineralocorticoids<...
TY - JOUR. T1 - Control of chronic otitis media and sensorineural hearing loss in C3H/HeJ mice. T2 - Glucocorticoids vs mineralocorticoids. AU - MacArthur, Carol J.. AU - Kempton, J. Beth. AU - DeGagne, Jacqueline. AU - Trune, Dennis R.. PY - 2008/11. Y1 - 2008/11. N2 - Objective: The impact of glucocorticoids and mineralocorticoids on chronic otitis media (COM) in toll-like receptor 4-deficient C3H/HeJ mice was investigated. Study Design: To evaluate control of COM by steroids with differences in their anti-inflammatory (prednisolone, dexamethasone), and fluid absorption functions (fludrocortisone, aldosterone). A minimum sample size of five animals for each group was required based on power analysis calculations. Sample sizes ranged from 7 to 17 mice per treatment group. Subjects and Methods: Auditory brain stem response (ABR) thresholds were performed at baseline, 2 weeks and 4 weeks. Histopathologic test results were evaluated on all mice ears at the end of the study. Results: Analysis of ...
Multi-species bacterial biofilm and intracellular infection in otitis media | BMC Pediatrics | Full TextMulti-species bacterial biofilm and intracellular infection in otitis media | BMC Pediatrics | Full Text
Bacteria which are metabolically active yet unable to be cultured and eradicated by antibiotic treatment are present in the middle ear effusion of children with chronic otitis media with effusion (COME) and recurrent acute otitis media (rAOM). These observations are suggestive of biofilm presence or intracellular sequestration of bacteria and may play a role in OM pathogenesis. The aim of this project is to provide evidence for the presence of otopathogenic bacteria intracellularly or within biofilm in the middle ear mucosa of children with COME or rAOM. Middle ear mucosal biopsies from 20 children with COME or rAOM were examined for otopathogenic bacteria (either in biofilm or located intracellularly) using transmission electron microscopy (TEM) or species specific fluorescent in situ hybridisation (FISH) and confocal laser scanning microscopy (CLSM). One healthy control biopsy from a child undergoing cochlear implant surgery was also examined. No bacteria were observed in the healthy control sample.
Paparella Otopathology Laboratory - Praesent Et Urna TurpisPaparella Otopathology Laboratory - Praesent Et Urna Turpis
Chronic otitis media is characterized by the presence of intractable tissue pathology such as granulation tissue, fibrosis, cholesterol granuloma, cholesteatoma, ossicular erosin, or new bone formation, with or without associate middle ear effusion. This is the most serious form of otitis media and at present can only be corrected by surgical intervention.. The etiology of chronic otitis media is repeated episodes of the other forms previously described. Although this classification was previously based on the presence of a perforated tympanic membrane, it is currently accepted that chronic otitis media can exist behind an intact and normal appearing tympanic membrane "silent otitis media". The following are examples of chronic otitis media showing intractable tissue pathology.. ...
Tympanostomy tube - WikipediaTympanostomy tube - Wikipedia
Tympanostomy tube, also known as a grommet or myringotomy tube, is a small tube inserted into the eardrum in order to keep the middle ear aerated for a prolonged period of time, and to prevent the accumulation of fluid in the middle ear. The operation to insert the tube involves a myringotomy and is performed under local or general anesthesia. The tube itself is made in a variety of designs. The most commonly used type is shaped like a grommet. When it is necessary to keep the middle ear ventilated for a very long period, a "T"-shaped tube may be used, as these "T-tubes" can stay in place for 2-4 years. Materials used to construct the tube are most often plastics such as silicone or Teflon. Stainless steel tubes exist, but are no longer in frequent use. Guidelines state that tubes are an option in: Recurrent acute otitis media: three ear infections in six months or four infections in a year. The evidence for this recommendation; however, is weak. Chronic otitis media with persistent effusion for ...
UPMC Physician Resources: Diagnosis and Management of Acute Otitis MediaUPMC Physician Resources: Diagnosis and Management of Acute Otitis Media
Its a pleasure for me to present to friends and colleagues about our work over the recent yeas in the diagnosis and management of acute otitis media. I have to disclose that through the University of Pittsburgh I hold two pending patents in this area. As a framework for this presentation I will use the American Academy of Pediatrics 2013 Diagnosis and Management Guideline. This is a frequently occurring problem, its the most common reason for children to be prescribed an antimicrobial, acute otitis media accounts for 18% of ambulatory visits, 11 million visits every year. There are bout 280,000 tube operations being done yearly in children less than 3 years. There is a direct cost for management of this condition of $2 billion a year. The peak incidence is during the first 2 years of life. 60 to 70% of children experience an episode of acute otitis media before their first birthday. Onset during the first 6 months is associated with the likelihood of recurrent acute otitis media. And recurrent ...
Risk for Speech Disorder Associated With Early Recurrent Otitis Media With EffusionTwo Retrospective Studies | Journal of...Risk for Speech Disorder Associated With Early Recurrent Otitis Media With EffusionTwo Retrospective Studies | Journal of...
The goals of this two-part series on children with histories of early recurrent otitis media with effusion (OME) were to assess the risk for speech disorder with and without hearing loss and to develop a preliminary descriptive-explanatory model for the findings. Recently available speech analysis programs, lifespan reference data, and statistical techniques were implemented with three cohorts of children with OME and their controls originally assessed in the 1980s: 35 typically developing 3-year-old children followed since infancy in a university-affiliated pediatrics clinic, 50 typically developing children of Native American background followed since infancy in a tribal health clinic, and (in the second paper) 70 children followed prospectively from 2 months of age to 3 years of age and older. Dependent variables included information from a suite of 10 metrics of speech production (Shriberg, Austin, Lewis, McSweeny, & Wilson, 1997a, 1997b) . Constraints on available sociodemographic and ...
https://www.thefreelibrary.com/Microbiological+evaluation+of+active+chronic+otitis+media+at+base...-a0467680712https://www.thefreelibrary.com/Microbiological+evaluation+of+active+chronic+otitis+media+at+base...-a0467680712
Free Online Library: Microbiological evaluation of active chronic otitis media at base hospital Srikot, Uttarakhand.(ORIGINAL ARTICLE, Uttarakhand, India, Report) by Journal of Evolution of Medical and Dental Sciences; Health, general Otitis media Causes of Pathogenic microorganisms Identification and classification Prevalence studies (Epidemiology)
Direct Expenditures Related to Otitis Media Diagnoses: Extrapolations From a Pediatric Medicaid Cohort | ELECTRONIC ARTICLE |...Direct Expenditures Related to Otitis Media Diagnoses: Extrapolations From a Pediatric Medicaid Cohort | ELECTRONIC ARTICLE |...
This article estimates costs associated with the diagnosis of otitis media, as recorded in claims data. Our algorithm for identifying otitis media relied on recording of diagnoses at the 3-digit ICD-9 level in combination with the presence of an antibiotic fill, a technique that has been has been shown to have 96% agreement with the medical chart.4 Although the estimate so obtained may understate the actual incidence of otitis media, for the purposes of estimating costs, it is appropriate because episodes of otitis media that do not result in visits to a health care provider have no impact on cost. Moreover, our estimate of cumulative otitis media among children 7 to 12 months of age (42%) is similar to the estimate by Duncan et al9 of otitis media among children 1 year of age (47%).. This study assesses expenditures from the point of view of the health care system; that is, no social costs, such as lost work time, or expenditures not normally covered by insurance, such as those for ...
Passive Smoking and Middle Ear Effusion Among Children in Day Care | American Academy of PediatricsPassive Smoking and Middle Ear Effusion Among Children in Day Care | American Academy of Pediatrics
One hundred thirty-two children who attended a research day-care center were studied to determine whether passive tobacco smoke exposure was associated with an increased rate of otitis media with effusion or with an increased number of days with otitis media with effusion during the first 3 years of life. Based on preliminary studies, a serum cotinine concentration of ≥2.5 ng/mL was considered indicative of exposure to tobacco smoke. Otitis media with effusion was diagnosed using pneumatic otoscopy by nurse practitioners and pediatricians who reviewed the childrens health status each weekday. The 87 children with serum cotinine concentrations ≥2.5 ng/mL had a 38% higher rate of new episodes of otitis media with effusion during the first 3 years of life than the 45 children with lower or undetectable serum cotinine concentrations (incidence density ratio = 1.38, 95% confidence interval 1.21 to 1.56). The average duration of an episode of otitis media with effusion was 28 days in the children ...
Myringotomy and Ear Tubes - symptoms, stages, Definition, Purpose, Description, RisksMyringotomy and Ear Tubes - symptoms, stages, Definition, Purpose, Description, Risks
Myringotomy with the insertion of ear tubes is an optional treatment for inflammation of the middle ear with fluid collection (effusion), also called glue ear, that lasts more than three months (chronic otitis media with effusion) and does not respond to drug treatment. Myringotomy is the recommended treatment if the condition lasts four to six months. Effusion is the collection of fluid that escapes from blood vessels or the lymphatic system. In this case, the effusion collects in the childs middle ear. Initially, acute inflammation of the middle ear with effusion is treated with one or two courses of antibiotic drugs. Antihistamines and decongestants have also been used to treat otitis media, but they have not been proven effective unless the child also has hay fever or some other allergic inflammation that contributes to the ear problem. Myringotomy with or without the insertion of ear tubes is not recommended as the initial treatment for otherwise healthy children with middle ear ...
Rumored Buzz on pediatric chiropractorRumored Buzz on pediatric chiropractor
There is certainly proof to indicate that gentle-tissue manipulative methods utilized in excess of the neck area may possibly assist Restoration from secretory otitis media (inflammation of the center ear) by opening the eustachian tube to aid drainage of fluids from the center ear (Mills 2003). Chiropractors who manipulate a kids neck to correct subluxations might present some symptomatic reduction for otitis media by inadvertently stretching the eustachian tube. But the risk of these treatment would outweigh any feasible benefit. (While otitis media is Ordinarily self-limiting, it should be saved underneath observation by a pediatrician who can prescribe antibiotics, if required, when There is certainly acute otitis media with bacterial infection. Otitis media usually happens in young more info children under three many years of age ...
CSF Otic Powder with Insufflator | Treatment for Chronic Otitis MediaCSF Otic Powder with Insufflator | Treatment for Chronic Otitis Media
CSF Otic powder applied with an insfufflator is a simple, effective method for managing chronic otitis media and, in some cases, of otitis externa.
Etiology of Acute Otitis Media and Characterization of Pneumococcal Isolates After Introduction of 13-Valent Pneumococcal...Etiology of Acute Otitis Media and Characterization of Pneumococcal Isolates After Introduction of 13-Valent Pneumococcal...
TY - JOUR. T1 - Etiology of Acute Otitis Media and Characterization of Pneumococcal Isolates After Introduction of 13-Valent Pneumococcal Conjugate Vaccine in Japanese Children. AU - AOM Surveillance Study Group. AU - Ubukata, Kimiko. AU - Morozumi, Miyuki. AU - Sakuma, Megumi. AU - Takata, Misako. AU - Mokuno, Eriko. AU - Tajima, Takeshi. AU - Iwata, Satoshi. PY - 2018/6/1. Y1 - 2018/6/1. N2 - BACKGROUND: Acute otitis media is a leading cause of childhood morbidity and antibiotic prescriptions. We examined etiologic changes in acute otitis media after introduction of 13-valent pneumococcal conjugate vaccine as routine immunization for Japanese children in 2014. Serotypes, resistance genotypes, antibiotic susceptibilities and multilocus sequence typing of pneumococcal isolates were also characterized. METHODS: Otolaryngologists prospectively collected middle ear fluid from 582 children by tympanocentesis or sampling through a spontaneously ruptured tympanic membrane between June 2016 and January ...
Risk factors for carriage of AOM pathogens during the first 3 years of life in children with early onset of acute otitis media.Risk factors for carriage of AOM pathogens during the first 3 years of life in children with early onset of acute otitis media.
article{d504bbe8-fe90-46ea-9bd6-993ead6999d2, abstract = {Abstract Conclusion: Risk factors associated with increased carriage rates are the same in children with recurrent acute otitis media (rAOM) as in healthy children. These are also known to be risk factors for the development of AOM itself. Objectives: The aim of this study was to describe risk factors for nasopharyngeal carriage in a cohort of young children at high risk of developing rAOM. Methods: Children with an onset of AOM before 6 months of age, indicating an 80% risk of developing rAOM, were enrolled in a vaccination trial on heptavalent PCV. These children were monitored for 3 years during healthy and AOM periods with nasopharyngeal cultures, physical examinations, and questionnaires. Results: A total of 109 children were included at a mean age of 5 months; 105 were followed for 3 years, 89 (82%) of whom developed rAOM. Risk factors associated with increased carriage of all major AOM pathogens were age <2 years, concurrent ...
ECOPLUS: ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380] - Grommets, Fittings, Valves, Adapters,...ECOPLUS: ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380] - Grommets, Fittings, Valves, Adapters,...
ECOPLUS ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY EcoPlus Grommets Bagged and Bulk 3/4 IN GROMMET (250/BOX) Sold in bags or box quantities only. ECOPLUS: ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380] - Grommets, Fittings, Valves, Adapters, Support Stakes & Fasteners - Pumps, Irrigation & Watering Supplies - Gardening & Hydroponics Store -
Thornton, R. B.<...Thornton, R. B.<...
I am a BrightSpark Foundation Research Fellow with the UWA School of Paediatrics and Child Health and Honorary Research Fellow with the Telethon Kids Institute. My research interests lie in understanding the interactions between bacteria and the host in chronic and recurrent respiratory infections including ear, nose and throat infections and chronic lung disease. I was awarded my PhD in 2011 from the University of Western Australia under the mentorship of Associate Professor Peter Richmond, Clinical Professor Harvey Coates and Associate Professor Paul Rigby. During my PhD I demonstrated that otopathogenic bacteria exist in both biofilms and intracellularly in the middle ear mucosa of Indigenous and non-Indigenous children with chronic and recurrent otitis media. I also demonstrated that the middle ear effusion contains host DNA which can be used by the bacteria as scaffolding to maintain an infectious reservoir in the middle ear. This DNA scaffolding may provide a treatment target to prevent ...
Office Tympanostomy Tube Placement - Fort Worth ENT & SinusOffice Tympanostomy Tube Placement - Fort Worth ENT & Sinus
Office tympanostomy tube placement or ventilation tube insertion is one of the most basic and simplest procedures performed by our ear surgeons.
Ear Ventilation Tubes | DAN Southern AfricaEar Ventilation Tubes | DAN Southern Africa
​My 13-year-old son is scheduled to begin scuba lessons. When he was about 7 years old, he had tubes placed in his eardrums for frequent ear infections. He has not had any trouble in several years, but I am wondering if it will be all right for him to dive. ​Placing small ventilation tubes through the eardrum (tympanic membrane) is not an unusual practice to help interrupt the cycle of repetitive...
Ear Ventilation Tubes | DAN Southern AfricaEar Ventilation Tubes | DAN Southern Africa
​My 13-year-old son is scheduled to begin scuba lessons. When he was about 7 years old, he had tubes placed in his eardrums for frequent ear infections. He has not had any trouble in several years, but I am wondering if it will be all right for him to dive. ​Placing small ventilation tubes through the eardrum (tympanic membrane) is not an unusual practice to help interrupt the cycle of repetitive...
Risk Factors of Boston et al for a Child Undergoing Multiple Tympanostomy Tube Insertions | Medicalalgorithms.comRisk Factors of Boston et al for a Child Undergoing Multiple Tympanostomy Tube Insertions | Medicalalgorithms.com
Boston et al identified risk factors associated with a child requiring multiple typanostomy tube insertions. The authors are from the Eastern Virginia Medical School and Childrens Hospital of the Kings Daughters in Norfolk, Virginia.
Oral prednisolone for acute otitis media in children: protocol of a pilot randomised, open-label, controlled study (OPAL study)...Oral prednisolone for acute otitis media in children: protocol of a pilot randomised, open-label, controlled study (OPAL study)...
TY - JOUR. T1 - Oral prednisolone for acute otitis media in children. T2 - protocol of a pilot randomised, open-label, controlled study (OPAL study). AU - Ranakusuma, Respati W. AU - McCullough, Amanda R. AU - Safitri, Eka D. AU - Pitoyo, Yupitri. AU - Widyaningsih, null. AU - Del Mar, Christopher B. AU - Beller, Elaine M. PY - 2018. Y1 - 2018. N2 - Background: Acute otitis media (AOM) is an acute inflammation of the middle ear commonly found in children, for which antibiotics are frequently prescribed. However, antibiotics are beneficial for only one third of AOM cases, and then, with only modest benefit. Since antibiotic use leads to risk of side effects and resistance, effective alternative treatments are required. Corticosteroids are a candidate because of their anti-inflammatory effects, although evidence of their efficacy and harms is insufficient. Accordingly, we plan a large, rigorous clinical trial to test this. Initially, we will test pre-specified methods and procedures (including the ...
Otitis MediaOtitis Media
... (OM) is the inflammation of the middle ear, usually accompanied by ear pain, and the two main types are otitis media with effusion (OME) and acute otitis media (AOM). This may lead to pulling at the ear, poor sleep and increased crying in young children. This is the forum for discussing anything related to OM
ECOPLUS: ECOPLUS 3/4 RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380]ECOPLUS: ECOPLUS 3/4" RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380]
ECOPLUS ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY EcoPlus Grommets Bagged and Bulk 3/4 IN GROMMET (250/BOX) Sold in bags or box quantities only. ECOPLUS: ECOPLUS 3/4 inch RUBBER GROMMET (250/BOX) - SOLD IN BULK ONLY [708380] - Grommets, Fittings, Valves, Adapters, Support Stakes & Fasteners - Pumps, Irrigation & Watering Supplies - Gardening & Hydroponics Store -
Lymphocyte Migration to the Middle Ear MucosaLymphocyte Migration to the Middle Ear Mucosa
We investigated the migration of antigen-specific IgA-forming cells to the middle ear mucosa. Antigen-specific lymphocytes of IgA and IgG classes were induced in guinea pigs according to an immunization strategy previously described. From those animals, chromium 51-labeled lymphocytes of Peyers pat
Otitis media with effusion and atopy: is there a causal relationship? | World Allergy Organization Journal | Full TextOtitis media with effusion and atopy: is there a causal relationship? | World Allergy Organization Journal | Full Text
Eosinophilic otitis media (EOM) is an intractable form of otitis media characterized by the presence of a highly viscous yellow effusion containing eosinophils. EOM shows a very high rate of association with asthma. It is resistant to conventional treatments for otitis media. However, EOM associated with adult-onset asthma has been shown to improve following optimal asthma therapy [16, 17]. EOM predominantly affects women in their fifties.. High-tone hearing loss is more frequently found and more severe in EOM patients, and sudden deafness is also seen sometimes. EOM occurs bilaterally, mostly, although the onset of disease in each ear may differ. EOM is often associated with asthma both in non-atopic and atopic asthmatics. Studies looking at the relation of EOM and asthma severity have shown that asthma severity was statistically greater in patients with EOM than in patients without EOM. EOM is often complicated by eosinophilic rhinosinusitis [18, 19]. Moreover, there was a close relationship ...
Grommets in otitis media with effusion: an individual patient data meta-analysis | Archives of Disease in ChildhoodGrommets in otitis media with effusion: an individual patient data meta-analysis | Archives of Disease in Childhood
The pooled results of meta-analysable studies confirm that treatment with short term ventilation tubes produces limited hearing improvement of only short duration-that is, only as long as the tubes are in situ and patent. Children aged 3 years or younger attending day-care and children aged 4 years or older with a hearing level of 25 dB HL or greater in both ears persisting for at least 12 weeks might benefit more from treatment with such ventilation tubes. Baseline hearing level, however, did not emerge as a clear selection criterion in the way suggested by current guidelines and by prevailing professional belief-that is, average hearing level at baseline did not obviously modify the effect estimate.. Interaction results for baseline hearing level with treatment differed between the trials that randomised children and trials that randomised ears. This difference is probably due to four factors. The first is the control for individual variance achieved by analysing treatment effects within ...
Plus itPlus it
Questionnaires on antibiotic treatment of acute otitis media in children were sent to the general practitioners who make regular referrals to clinics in the Kings College Hospital group. The most popular first choice of drug was amoxycillin (44%), but 37% of general practitioners said that they often used oral phenoxymethylpenicillin. This drug has relatively low activity against Haemophilus influenzae and many strains of Staphylococcus aureus. It is poorly absorbed from the stomach, does not penetrate the middle ear well, and its use may be one factor in the development of chronic middle ear effusions after acute otitis media. Sixty two per cent of the doctors who replied never treated acute otitis media with intramuscular antibiotics, but 57% used oral loading doses. Ninety seven per cent never treated their patients without antibiotics. ...
Otitis Media With Effusion in Children: A Pediatric Office PerspectiveOtitis Media With Effusion in Children: A Pediatric Office Perspective
Pediatric Annals | Otitis media with effusion (OME) refers to a painless collection of middle ear fluid without signs of acute infection. Symptoms might include hearing loss, behavioral changes such as inattentiveness, and, in the older child, occasional complaints of a blocked up or plugged ear. Although OME can arise without preceding infection, most cases evolve from acute otitis media (AOM). There is a
Do kids need ear tubes for infections and fluid buildup? | ReutersDo kids need ear tubes for infections and fluid buildup? | Reuters
By Lisa RapaportIts hard to say for sure which kids will benefit most from a common childhood surgery for infections and fluid buildup in the middle ear, a research review suggests. The reviewers focused on a procedure known as tympanostomy, surgery to place tiny tubes in the eardrum that help improve air flow and prevent fluid accumulation in the middle ear. They looked at both whats known as otitis media with effusion, or chronic accumulation of fluid thats not infected, as well as recurrent acute otitis media, or a buildup of infected pus that can be painful and put pressure on the ear drum. The study team analyzed data combined from 147 previously published articles on the surgery and found it associated with less short-term hearing loss in kids with a chronic buildup of uninfected fluid but no evidence of benefit by 12 to 24 months compared to children who didnt get the treatment. Kids with acute infections may have fewer episodes after surgery, but evidence is limited, the review also found.
Is There an Optimal Location for Tympanostomy Tube Placement? - ENTtodayIs There an Optimal Location for Tympanostomy Tube Placement? - ENTtoday
There is no body of evidence to suggest that there is an optimal location for placing tympanostomy tubes, yet the anterior-inferior quadrant is commonly used
Small otitis media actually caused a coma Otitis E.N.T. Rehabilitation BlogSmall otitis media actually caused a coma Otitis E.N.T. Rehabilitation Blog
Small otitis media actually caused a coma,Http://www.sina.com.cn 2005 03 13:51 Yangtze Evening News, 10Washington due to otitis media without timely treatment due to serious infectio
Tympanostomy TubesTympanostomy Tubes
East Bay Snoring and Sinus utilizes tympanostomy tubes to greatly reduce the occurrence of further ear infections for patients in Walnut Creek and Concord CA.
MyringotomyMyringotomy
Ramesh C. DekaRamesh C. Deka
AmblyaudiaAmblyaudia
George Siber bibliographyGeorge Siber bibliography
Staphylococcal infectionStaphylococcal infection
Auditory processing disorderAuditory processing disorder
Lakhumal Hiranand HiranandaniLakhumal Hiranand Hiranandani
CFHR5CFHR5
Tympanic membrane retractionTympanic membrane retraction
TympanosclerosisTympanosclerosis
AutoinflationAutoinflation
Pneumatic otoscopyPneumatic otoscopy
Cleft lip and cleft palateCleft lip and cleft palate
OXGR1OXGR1
Tympanostomy tubeTympanostomy tube
Patulous Eustachian tubePatulous Eustachian tube
Audiology and hearing health professionals in developed and developing countriesAudiology and hearing health professionals in developed and developing countries
TonsillectomyTonsillectomy
Auditory processing disorderAuditory processing disorder
SpeechSpeech
60S ribosomal protein L3860S ribosomal protein L38
PolitzerizationPolitzerization
SplicemanSpliceman
Conductive hearing lossConductive hearing loss
Hearing testHearing test
TebipenemTebipenem
Down syndromeDown syndrome
TympanometryTympanometry
Wikipedia:WikiProject Medicine/Cochrane/Cochrane Review List/Musculoskeletal, Oral, Skin and SensoryWikipedia:WikiProject Medicine/Cochrane/Cochrane Review List/Musculoskeletal, Oral, Skin and Sensory
Interleukin 8Interleukin 8
SpeechSpeech
BronchitisBronchitis
Phonological awarenessPhonological awareness
Temporomandibular joint dysfunctionTemporomandibular joint dysfunction
Alloiococcus otitisAlloiococcus otitis
MyocarditisMyocarditis
Hearing lossHearing loss
Uvimbe wa sikio, kamusi elezo huruUvimbe wa sikio, kamusi elezo huru
Down syndromeDown syndrome
ഓട്ടൈറ്റിസ് മീഡിയ - വിക്കിപീഡിയഓട്ടൈറ്റിസ് മീഡിയ - വിക്കിപീഡിയ
Spatial hearing lossSpatial hearing loss
GrommetGrommet
Adenoid hypertrophyAdenoid hypertrophy
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth Care
Otitis MediaOtitis Media with EffusionPleural EffusionOtitis Media, SuppurativeEar, MiddleOtitis ExternaPericardial EffusionPleural Effusion, MalignantMiddle Ear VentilationChinchillaEustachian TubeOtitisOtoscopyHaemophilus influenzaeCulture MediaMastoiditisAcoustic Impedance TestsHaemophilus InfectionsPneumococcal InfectionsAcute DiseaseTympanic MembraneExudates and TransudatesTympanic Membrane PerforationMoraxellaceae InfectionsLabyrinthitisStreptococcus pneumoniaeMoraxella (Branhamella) catarrhalisNasopharynxOtolaryngologyAmoxicillin-Potassium Clavulanate CombinationCholesteatoma, Middle EarTuberculosis, PleuralLymphoma, Primary EffusionAdenoidsEar DiseasesAmoxicillinTympanoplastyOtoscopesMastoidHearing LossRespiratory Tract InfectionsSulfisoxazoleDiagnostic Techniques, OtologicalEaracheAdenoidectomyRecurrenceEar CanalPericardiocentesisCardiac TamponadePneumococcal VaccinesNeisseriaceae InfectionsAnti-Bacterial AgentsPleuraVaccines, ConjugateChronic DiseaseHearing TestsChild Day Care CentersEmpyema, PleuralSinusitisSubdural EffusionAzithromycinCefaclorMucous MembraneHearing Loss, ConductivePleurodesisDisease Models, AnimalAudiometryBacterial InfectionsXylitolNasopharyngeal DiseasesAscitic FluidProspective StudiesMass MediaOtologic Surgical ProceduresPleural CavityHydrothoraxDrainageMyringoplastyParacentesisTreatment OutcomeAntibodies, BacterialPericarditisEar OssiclesStreptolysinsChylothoraxCefuroximeInfant, NewbornFacial ParalysisHaemophilus VaccinesHuman bocavirusRetrospective StudiesCerumenTime FactorsHerpesvirus 8, HumanCulture Media, ConditionedAscites
Review: parental smoking increases risk of recurrent otitis media, middle ear effusion, and tonsillectomy or adenoidectomy in...Review: parental smoking increases risk of recurrent otitis media, middle ear effusion, and tonsillectomy or adenoidectomy in...
Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.
Effect of recolonisation with interfering α streptococci on recurrences of acute and secretory otitis media in children:...Effect of recolonisation with "interfering" α streptococci on recurrences of acute and secretory otitis media in children:...
Glue EarGlue Ear
Otitis media with effusion: MedlinePlus Medical EncyclopediaOtitis media with effusion: MedlinePlus Medical Encyclopedia
Passive smoking and otitis media with effusion. | The BMJPassive smoking and otitis media with effusion. | The BMJ
Otitis Media with Effusion: Causes, Symptoms, and DiagnosisOtitis Media with Effusion: Causes, Symptoms, and Diagnosis
Otitis Media With Effusion Clinical Presentation: History, Physical ExaminationOtitis Media With Effusion Clinical Presentation: History, Physical Examination
Otitis Media with Effusion - American Family PhysicianOtitis Media with Effusion - American Family Physician
Otitis Media with Effusion (OME) | Childrens Hospital of PhiladelphiaOtitis Media with Effusion (OME) | Children's Hospital of Philadelphia
Evidence of bacterial metabolic activity in culture-negative otitis media with effusion. - PubMed - NCBIEvidence of bacterial metabolic activity in culture-negative otitis media with effusion. - PubMed - NCBI
Appendix C: The algorithms | Otitis media with effusion in under 12s: surgery | Guidance | NICEAppendix C: The algorithms | Otitis media with effusion in under 12s: surgery | Guidance | NICE
Otitis Media With Effusion in Children: A Pediatric Office PerspectiveOtitis Media With Effusion in Children: A Pediatric Office Perspective
Allergic Rhinitis Is Associated With Otitis Media With Effusion: A Birth Cohort Study | American Academy of PediatricsAllergic Rhinitis Is Associated With Otitis Media With Effusion: A Birth Cohort Study | American Academy of Pediatrics
Otitis media with effusion Information | Mount Sinai - New YorkOtitis media with effusion Information | Mount Sinai - New York
What is an otitis media with effusion ear infection? | Ear Disorders - SharecareWhat is an otitis media with effusion ear infection? | Ear Disorders - Sharecare
Otitis media with effusion | definition of otitis media with effusion by Medical dictionaryOtitis media with effusion | definition of otitis media with effusion by Medical dictionary
The Effect of Ventilation Tubes on Language Development in Infants With Otitis Media With Effusion: A Randomized Trial |...The Effect of Ventilation Tubes on Language Development in Infants With Otitis Media With Effusion: A Randomized Trial |...
Otitis Media With Effusion Treatment & Management: Overview of Medical and Surgical Approaches, Modification of OME Risk...Otitis Media With Effusion Treatment & Management: Overview of Medical and Surgical Approaches, Modification of OME Risk...
Comparison of Three Methods Used in the Diagnosis of Extraesophageal Reflux in Children with Chronic Otitis Media with EffusionComparison of Three Methods Used in the Diagnosis of Extraesophageal Reflux in Children with Chronic Otitis Media with Effusion
Management of deafness in otitis media with effusion | The Journal of the American Osteopathic AssociationManagement of deafness in otitis media with effusion | The Journal of the American Osteopathic Association
The Effect of Osteopatic Cranial Techniques on the Audiometric and Tympanometric Values in Children Suffering From Otitis Media...The Effect of Osteopatic Cranial Techniques on the Audiometric and Tympanometric Values in Children Suffering From Otitis Media...
PRIME PubMed | The role of IgE-mediated hypersensitivity in the development of otitis media with effusion: a reviePRIME PubMed | The role of IgE-mediated hypersensitivity in the development of otitis media with effusion: a revie
International consensus (ICON) on management of otitis media with effusion in children - EM|consulteInternational consensus (ICON) on management of otitis media with effusion in children - EM|consulte
Bacterial Species and Antibiotic Sensitivity in Korean Patients Diagnosed with Acute Otitis Media and Otitis Media with...Bacterial Species and Antibiotic Sensitivity in Korean Patients Diagnosed with Acute Otitis Media and Otitis Media with...
Autoinflation reduces middle ear effusion in children with otitis media with effusion | BMJ Evidence-Based MedicineAutoinflation reduces middle ear effusion in children with otitis media with effusion | BMJ Evidence-Based Medicine
The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion.The immunoregulatory and allergy-associated cytokines in the aetiology of the otitis media with effusion.
The Proposed Usage of Intranasal Steroids and Antihistamines for Otitis Media with Effusion | Springer for Research &...The Proposed Usage of Intranasal Steroids and Antihistamines for Otitis Media with Effusion | Springer for Research &...
Grommets in otitis media with effusion: an individual patient data meta-analysis | Archives of Disease in ChildhoodGrommets in otitis media with effusion: an individual patient data meta-analysis | Archives of Disease in Childhood
Prevalence of Otitis Media With Effusion Among Children in Xian, China : A Randomized Survey in Chinas MainlandPrevalence of Otitis Media With Effusion Among Children in Xi'an, China : A Randomized Survey in China's Mainland
The role of topical nasal steroids in the treatment of children with otitis media with effusion for Awadalla John EffatThe role of topical nasal steroids in the treatment of children with otitis media with effusion for Awadalla John Effat
JaypeeDigital | Acute Otitis Media and Otitis Media with EffusionJaypeeDigital | Acute Otitis Media and Otitis Media with Effusion
Economic evaluation of surgical insertion of ventilation tubes for the management of persistent bilateral otitis media with...Economic evaluation of surgical insertion of ventilation tubes for the management of persistent bilateral otitis media with...
AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceNamed GroupsHealth Care
Otitis MediaOtitis Media with EffusionPleural EffusionOtitis Media, SuppurativeEar, MiddleOtitis ExternaPericardial EffusionPleural Effusion, MalignantMiddle Ear VentilationChinchillaEustachian TubeOtitisOtoscopyHaemophilus influenzaeCulture MediaMastoiditisAcoustic Impedance TestsHaemophilus InfectionsPneumococcal InfectionsAcute DiseaseTympanic MembraneExudates and TransudatesTympanic Membrane PerforationMoraxellaceae InfectionsLabyrinthitisStreptococcus pneumoniaeMoraxella (Branhamella) catarrhalisNasopharynxOtolaryngologyAmoxicillin-Potassium Clavulanate CombinationCholesteatoma, Middle EarTuberculosis, PleuralLymphoma, Primary EffusionAdenoidsEar DiseasesAmoxicillinTympanoplastyOtoscopesMastoidHearing LossRespiratory Tract InfectionsSulfisoxazoleDiagnostic Techniques, OtologicalEaracheAdenoidectomyRecurrenceEar CanalPericardiocentesisCardiac TamponadePneumococcal VaccinesNeisseriaceae InfectionsAnti-Bacterial AgentsPleuraVaccines, ConjugateChronic DiseaseHearing TestsChild Day Care CentersEmpyema, PleuralSinusitisSubdural EffusionAzithromycinCefaclorMucous MembraneHearing Loss, ConductivePleurodesisDisease Models, AnimalAudiometryBacterial InfectionsXylitolNasopharyngeal DiseasesAscitic FluidProspective StudiesMass MediaOtologic Surgical ProceduresPleural CavityHydrothoraxDrainageMyringoplastyParacentesisTreatment OutcomeAntibodies, BacterialPericarditisEar OssiclesStreptolysinsChylothoraxCefuroximeInfant, NewbornFacial ParalysisHaemophilus VaccinesHuman bocavirusRetrospective StudiesCerumenTime FactorsHerpesvirus 8, HumanCulture Media, ConditionedAscites
SecretoryFluidRecurrent acute otitiTypes of otitis mediaGlueMyringotomyTympanometryCleft PalateExperimental otitis media with effusionOtolaryngol Head Neck SurgEardrumAcute otitis externaEpisode of acute otitiEustachian tubeSuppurative otitisChildren with otitis mediaAbstractCases of otitis mediaManagement of Otitis MediaDevelopment of Otitis MediaOtolaryngologyTympanogramPurulent otitis mediaBilateral otitis mediaBacterialTympanostomy tubeVentilation tubesDevelop otitis mediaPediatric Otitis MediaPrevalenceSymptoms of otitisAdenoidectomyCause acute otitiAutoinflationPrognosisOccursComplicationsUpper respiratorAllergic RhinitisTreatmentOccurrenceTubes2000SteroidsChildhoodOnsetAdultsAntibiotics
Secretory8
Fluid41
Recurrent acute otiti4
Types of otitis media2
Glue7
Myringotomy6
Tympanometry4
Cleft Palate3
Experimental otitis media with effusion1
Otolaryngol Head Neck Surg2
  • A1 - Bernstein,J M, PY - 1993/9/1/pubmed PY - 1993/9/1/medline PY - 1993/9/1/entrez SP - 611 EP - 20 JF - Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery JO - Otolaryngol Head Neck Surg VL - 109 IS - 3 Pt 2 N2 - Otitis media with effusion is the most common cause of hearing loss in children today. (unboundmedicine.com)
  • In this study, researchers also discovered that various of inflammatory mediators such as histamine have been detected in middle ear effusions of the children who had OME [Arch Otolaryngol Head Neck Surg 1988;114:1131- (pachaworld.org)
Eardrum6
Acute otitis externa5
  • For acute otitis externa, administer OTIPRIO as a single 0.2 mL (12 mg) administration to the external ear canal of each affected ear of patients aged 6 months and older. (drugs.com)
  • Figure 1: Preparation and dosing directions for Acute Otitis Externa and for Otitis Media with Effusion. (drugs.com)
  • In a single randomized, sham controlled Phase 3 clinical trial, 259 pediatric and adult patients with acute otitis externa were treated with OTIPRIO or sham administered by a healthcare professional to the external ear canal as a single dose (0.2 mL to each affected ear). (drugs.com)
  • The diagnosis of acute otitis media (AOM) should be made in children who present with moderate to severe bulging of the tympanic membrane (TM) or new onset of ottorhea not due to acute otitis externa or mild bulging of the TM and recent (less than 48 hours) onset of ear pain or intense erythema of the TM. (aafp.org)
  • The safety and effectiveness of OTIPRIO in infants below six months of age have not been established for the treatment of pediatric patients with bilateral otitis media with effusion undergoing tympanostomy tube placement and acute otitis externa. (otiprio.com)
Episode of acute otiti4
Eustachian tube9
Suppurative otitis2
Children with otitis media5
  • An open, pragmatic, randomized trial by Williamson et al also supported the efficacy of autoinflation, finding that in children with otitis media with effusion, it cleared effusions and improved symptoms. (medscape.com)
  • Children with otitis media with effusion will be treated with osteopatic cranial techniques or with a placebo treatment. (clinicaltrials.gov)
  • To identify subgroups of children with otitis media with effusion (OME) that might benefit more than others from treatment with ventilation tubes. (bmj.com)
  • It aims to improve hearing and quality of life in children with otitis media. (nice.org.uk)
  • Abdelshafy IA, Atalla AT, AbdELAziz AE, Shehata WM, Gendy OAE (2015) Pepsinogen Assay as a Marker of Reflux in Children with Otitis Media with Effusion. (medcraveonline.com)
Abstract3
  • abstract = "Although previous studies have shown that prostaglandins (PGs), leukotrienes (LTs), and other arachidonic acid (AA) metabolites play an important role in the pathogenesis of otitis media with effusion (OME), the exact role of each AA metabolite in OME is still unknown. (elsevier.com)
  • A. Prevalence, features of the clinical course and effectiveness of the surgical treatment of otitis media with effusion in children: Abstract of PhD Thesis. (ijbm.org)
  • Abstract Introduction Otitis media with effusion (OME) is a leading cause of hearing impairment in children . (bvsalud.org)
Cases of otitis media2
  • Neither the affected children nor their parents describe reports referable to a middle ear effusion in 40-50% of documented cases of otitis media with effusion. (medscape.com)
  • Objective: To investigate, in cases of otitis media with effusion (OME), the correlation of the TM color changes with the presence and viscosity of the effusion in the middle ear. (bezmialem.edu.tr)
Management of Otitis Media3
  • Pharmacologic management of otitis media with effusion (OME) includes administration of antimicrobial agents, steroids, antihistamines and decongestants, and mucolytics. (medscape.com)
  • The guideline, The Diagnosis and Management of Otitis Media , was developed by the American Academy of Pediatrics and endorsed by the American Academy of Family Physicians. (aafp.org)
  • Objectives The objective of this research is to assess the efficacy of intratympanic (IT) steroids injection for management of otitis media with effusion (OME). (bvsalud.org)
Development of Otitis Media5
  • Erdivanli OC, Coskun ZO, Kazikdas KC, Demirci M. Prevalence of Otitis Media with Effusion among Primary School Children in Eastern Black Sea, in Turkey and the Effect of Smoking in the Development of Otitis Media with Effusion. (medscape.com)
  • This report examines the role of immunoglobulin E-mediated hypersensitivity in the development of otitis media with effusion. (unboundmedicine.com)
  • Objectives: To study whether cyclooxygenase 2 (COX-2) plays a role in the development of otitis media with effusion (OME). (elsevier.com)
  • Age plays a factor in the development of otitis media. (sfsu.edu)
  • Skeletal changes play an important part in the development of otitis media. (sfsu.edu)
Otolaryngology1
  • The guideline, Otitis Media with Effusion , was updated by the American Academy of Otolaryngology-Head and Neck Surgeons and endorsed by the American Academy of Family Physicians. (aafp.org)
Tympanogram2
Purulent otitis media1
Bilateral otitis media5
  • The surgical insertion of Ventilation Tubes (VTs) for the management of persistent bilateral Otitis Media with Effusion (OME) in children remains a contentious issue due to the varying opinions regarding the risks and benefits of this procedure. (biomedcentral.com)
  • The treatment of pediatric patients with bilateral otitis media with effusion undergoing tympanostomy tube placement. (drugs.com)
  • For bilateral otitis media with effusion, administer OTIPRIO as a single intratympanic administration of one 0.1 mL (6 mg) dose into each affected ear of pediatric patients (6 months of age and older), following suctioning of middle ear effusion. (drugs.com)
  • In two randomized, sham-controlled Phase 3 clinical trials, 530 pediatric patients with bilateral otitis media with effusion undergoing tympanostomy tube placement were treated with OTIPRIO or sham administered intratympanically as a single dose. (drugs.com)
  • Examination revealed dehydration, bilateral otitis media, and normal respiratory function. (cdc.gov)
Bacterial6
Tympanostomy tube1
  • The purpose of this study is to identify the relation between the types of immune cells in otitis media with effusion (OME) and tympanostomy tube otorrhea (TTO) in children. (bvsalud.org)
Ventilation tubes3
Develop otitis media2
Pediatric Otitis Media1
Prevalence6
Symptoms of otitis2
Adenoidectomy3
Cause acute otiti1
  • Similar to isolates from acute otitis media, the most common are S. pneumoniae, H. influenzae, and M. catarrhalis, but the latter two organisms are more commonly isolated than pneumococcus.4 Resistance rates of these organisms are similar to rates found when these bacteria cause acute otitis media. (mussenhealth.us)
Autoinflation3
  • Several investigators have reported mixed results when attempting to determine if autoinflation, compared with no intervention, improves effusion clearance rates. (medscape.com)
  • To assess the effectiveness of autoinflation compared with no treatment in children and adults with otitis media with effusion. (edu.au)
  • However, because of the low cost and absence of adverse effects it is reasonable to consider autoinflation whilst awaiting natural resolution of otitis media with effusion. (edu.au)
Prognosis1
  • Forty three patients with congenital nasolacrimal duct obstruction were examined by an E.N.T. specialist in Prince Ali Hospital for presence or absence of otitis media with effusion to investigate the association, if any, between otitis media with effusion and congenital nasolacrimal duct obstruction along with its impact on prognosis. (iasj.net)
Occurs2
Complications3
Upper respirator2
  • OME is more common than AOM (acute otitis media), and may be caused by viral upper respiratory infections, allergies, or exposure to irritants (such as cigarette smoke). (sharecare.com)
  • Clinical research is providing evidence that children who inhale secondhand smoke may have a higher incidence of health problems such as upper respiratory infections, otitis media, tonsillitis, aggravation of chronic respiratory conditions, and sudden infant death syndrome. (bmj.com)
Allergic Rhinitis1
Treatment13
Occurrence2
Tubes3
20001
Steroids1
  • OSTRICH is a randomised controlled trial for otitis media with effusion (OME) in children, to determine the clinical and cost effectiveness of a short course of oral steroids. (biomedcentral.com)
Childhood7
Onset2
Adults2
  • Adults with otitis media with effusion report aural fullness and/or pressure, an ear being plugged, or decreased hearing. (medscape.com)
  • Adenoids and tonsils can be removed if they cause chronic otitis media, which is more common in children than in adults. (hse.ie)
Antibiotics2
Rheologic Studies on Middle Ear Effusions and Their Mucus Glycoproteins | JAMA Otolaryngology-Head & Neck Surgery | The JAMA...
Rheologic Studies on Middle Ear Effusions and Their Mucus Glycoproteins | JAMA Otolaryngology-Head & Neck Surgery | The JAMA... (jamanetwork.com)
Ear infections: Symptoms, types, and causes
Ear infections: Symptoms, types, and causes (medicalnewstoday.com)
JCI - Volume 118, Issue 2
JCI - Volume 118, Issue 2 (jci.org)
Pediatric Chronic Rhinosinusitis
Pediatric Chronic Rhinosinusitis (healio.com)
Otitis media with effusion Information | Mount Sinai - New York
Otitis media with effusion Information | Mount Sinai - New York (mountsinai.org)
September-October 1982 - Volume 1 - Issue 5 : The Pediatric Infectious Disease Journal
September-October 1982 - Volume 1 - Issue 5 : The Pediatric Infectious Disease Journal (journals.lww.com)
Tympanometry: MedlinePlus Medical Encyclopedia
Tympanometry: MedlinePlus Medical Encyclopedia (medlineplus.gov)
What is an otitis media with effusion ear infection? | Ear Disorders - Sharecare
What is an otitis media with effusion ear infection? | Ear Disorders - Sharecare (sharecare.com)
5 Best of 2017: Pediatrics Viewpoints
5 Best of 2017: Pediatrics Viewpoints (medscape.com)
Year 2007 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs
Year 2007 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs (asha.org)
Clinical Study of Solo Tympanostomy Tube Device (TTD) - Full Text View - ClinicalTrials.gov
Clinical Study of Solo Tympanostomy Tube Device (TTD) - Full Text View - ClinicalTrials.gov (clinicaltrials.gov)
Radiation Studies: Nasopharyngeal Radium Irradiation (NRI) - Bibliography | CDC RSB
Radiation Studies: Nasopharyngeal Radium Irradiation (NRI) - Bibliography | CDC RSB (cdc.gov)
Pediatric Ear Infections (Otitis Media)
Pediatric Ear Infections (Otitis Media) (childrens.com)
Prevalence of secretory otitius media among school children in Kuwait | The Journal of Laryngology & Otology | Cambridge Core
Prevalence of secretory otitius media among school children in Kuwait | The Journal of Laryngology & Otology | Cambridge Core (cambridge.org)
Passive smoking and otitis media with effusion. | The BMJ
Passive smoking and otitis media with effusion. | The BMJ (bmj.com)
Wolf-Hirschhorn Syndrome Clinical Presentation: History, Physical, Causes
Wolf-Hirschhorn Syndrome Clinical Presentation: History, Physical, Causes (emedicine.medscape.com)
Surveillance Manual | Pneumococcal | Vaccine Preventable Diseases | CDC
Surveillance Manual | Pneumococcal | Vaccine Preventable Diseases | CDC (cdc.gov)
Herpes Zoster Oticus - Ear, Nose, and Throat Disorders - Merck Manuals Professional Edition
Herpes Zoster Oticus - Ear, Nose, and Throat Disorders - Merck Manuals Professional Edition (merckmanuals.com)
Pneumatic Otoscope Examination: Overview, Indications, Contraindications
Pneumatic Otoscope Examination: Overview, Indications, Contraindications (emedicine.medscape.com)
Middle Ear Diseases | SpringerLink
Middle Ear Diseases | SpringerLink (link.springer.com)
International Conference on Communicative Disorders and Deaf Studies ICCDDS in August 2022 in New York
International Conference on Communicative Disorders and Deaf Studies ICCDDS in August 2022 in New York (waset.org)
Middle Ear Infection, Inflammation - Acute, Chronic Otitis Media | Healthhype.com
Middle Ear Infection, Inflammation - Acute, Chronic Otitis Media | Healthhype.com (healthhype.com)
Health 101: Ear Infections
Health 101: Ear Infections (parents.com)
Adenoidectomy: Background, History of the Procedure, Epidemiology
Adenoidectomy: Background, History of the Procedure, Epidemiology (emedicine.medscape.com)