Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
Breaks in bones resulting from low bone mass and microarchitectural deterioration characteristic of OSTEOPOROSIS.
Breaks in bones.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
A noninvasive method for assessing BODY COMPOSITION. It is based on the differential absorption of X-RAYS (or GAMMA RAYS) by different tissues such as bone, fat and other soft tissues. The source of (X-ray or gamma-ray) photon beam is generated either from radioisotopes such as GADOLINIUM 153, IODINE 125, or Americanium 241 which emit GAMMA RAYS in the appropriate range; or from an X-ray tube which produces X-RAYS in the desired range. It is primarily used for quantitating BONE MINERAL CONTENT, especially for the diagnosis of OSTEOPOROSIS, and also in measuring BONE MINERALIZATION.
Fractures occurring as a result of disease of a bone or from some undiscoverable cause, and not due to trauma. (Dorland, 27th ed)
A nonhormonal medication for the treatment of postmenopausal osteoporosis in women. This drug builds healthy bone, restoring some of the bone loss as a result of osteoporosis.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
A polypeptide that consists of the 1-34 amino-acid fragment of human PARATHYROID HORMONE, the biologically active N-terminal region. The acetate form is given by intravenous infusion in the differential diagnosis of HYPOPARATHYROIDISM and PSEUDOHYPOPARATHYROIDISM. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Broken bones in the vertebral column.
A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Bone loss due to osteoclastic activity.
The constricted portion of the thigh bone between the femur head and the trochanters.
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
The largest of the TARSAL BONES which is situated at the lower and back part of the FOOT, forming the HEEL.
Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.
Bone-forming cells which secrete an EXTRACELLULAR MATRIX. HYDROXYAPATITE crystals are then deposited into the matrix to form bone.
A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
The spinal or vertebral column.
The process of bone formation. Histogenesis of bone including ossification.
A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyroid cells and acts to decrease the formation and absorptive activity of osteoclasts. Its role in regulating plasma calcium is much greater in children and in certain diseases than in normal adults.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
The projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
The surgical removal of one or both ovaries.
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
Diseases of BONES.
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
The measurement of the density of a material by measuring the amount of light or radiation passing through (or absorbed by) the material.
The largest of three bones that make up each half of the pelvic girdle.
An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
Falls due to slipping or tripping which may result in injury.
The physiological period following the MENOPAUSE, the permanent cessation of the menstrual life.
The outer shorter of the two bones of the FOREARM, lying parallel to the ULNA and partially revolving around it.
The most common form of fibrillar collagen. It is a major constituent of bone (BONE AND BONES) and SKIN and consists of a heterotrimer of two alpha1(I) and one alpha2(I) chains.
Injuries involving the vertebral column.
Disorder caused by an interruption of the mineralization of organic bone matrix leading to bone softening, bone pain, and weakness. It is the adult form of rickets resulting from disruption of VITAMIN D; PHOSPHORUS; or CALCIUM homeostasis.
The region of the HAND between the WRIST and the FINGERS.
Injuries to the part of the upper limb of the body between the wrist and elbow.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
The growth and development of bones from fetus to adult. It includes two principal mechanisms of bone growth: growth in length of long bones at the epiphyseal cartilages and growth in thickness by depositing new bone (OSTEOGENESIS) with the actions of OSTEOBLASTS and OSTEOCLASTS.
The second longest bone of the skeleton. It is located on the medial side of the lower leg, articulating with the FIBULA laterally, the TALUS distally, and the FEMUR proximally.
Fractures of the short, constricted portion of the thigh bone between the femur head and the trochanters. It excludes intertrochanteric fractures which are HIP FRACTURES.
Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Crumbling or smashing of cancellous BONE by forces acting parallel to the long axis of bone. It is applied particularly to vertebral body fractures (SPINAL FRACTURES). (Blauvelt and Nelson, A Manual of Orthopedic Terminology, 1994, p4)
Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
Human males as cultural, psychological, sociological, political, and economic entities.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Process by which organic tissue becomes hardened by the physiologic deposit of calcium salts.
Therapeutic use of hormones to alleviate the effects of hormone deficiency.
These compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.
Death of a bone or part of a bone, either atraumatic or posttraumatic.
Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).
The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.
A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406)
Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time.
LDL-receptor related protein that combines with FRIZZLED RECEPTORS at the cell surface to form receptors that bind WNT PROTEINS. The protein plays an important role in the WNT SIGNALING PATHWAY in OSTEOBLASTS and during EMBRYONIC DEVELOPMENT.
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Decrease, loss, or removal of the mineral constituents of bones. Temporary loss of bone mineral content is especially associated with space flight, weightlessness, and extended immobilization. OSTEOPOROSIS is permanent, includes reduction of total bone mass, and is associated with increased rate of fractures. CALCIFICATION, PHYSIOLOGIC is the process of bone remineralizing. (From Dorland, 27th ed; Stedman, 25th ed; Nicogossian, Space Physiology and Medicine, 2d ed, pp327-33)
Fractures of the femur.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
Mature osteoblasts that have become embedded in the BONE MATRIX. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi.
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
The concept covering the physical and mental conditions of members of minority groups.
Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.
Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.

Dietary intake and practices in the Hong Kong Chinese population. (1/3580)

OBJECTIVES: To examine dietary intake and practices of the adult Hong Kong Chinese population to provide a basis for future public health recommendations with regard to prevention of certain chronic diseases such as cardiovascular disease, hypertension, and osteoporosis. PARTICIPANTS: Age and sex stratified random sample of the Hong Kong Chinese population aged 25 to 74 years (500 men, 510 women). METHOD: A food frequency method over a one week period was used for nutrient quantification, and a separate questionnaire was used for assessment of dietary habits. Information was obtained by interview. RESULTS: Men had higher intakes of energy and higher nutrient density of vitamin D, monounsaturated fatty acids and cholesterol, but lower nutrient density of protein, many vitamins, calcium, iron, copper, and polyunsaturated fatty acids. There was an age related decrease in energy intake and other nutrients except for vitamin C, sodium, potassium, and percentage of total calorie from carbohydrate, which all increased with age. Approximately 50% of the population had a cholesterol intake of < or = 300 mg; 60% had a fat intake < or = 30% of total energy; and 85% had a percentage of energy from saturated fats < or = 10%; criteria considered desirable for cardiovascular health. Seventy eight per cent of the population had sodium intake values in the range shown to be associated with the age related rise in blood pressure with age. Mean calcium intake was lower than the FAO/WHO recommendations. The awareness of the value of wholemeal bread and polyunsaturated fat spreads was lower in this population compared with that in Australia. There was a marked difference in types of cooking oil compared with Singaporeans, the latter using more coconut/palm/mixed vegetable oils. CONCLUSION: Although the current intake pattern for cardiovascular health for fat, saturated fatty acid, and cholesterol fall within the recommended range for over 50% of the population, follow up surveys to monitor the pattern would be needed. Decreasing salt consumption, increasing calcium intake, and increasing the awareness of the health value of fibre may all be beneficial in the context of chronic disease prevention.  (+info)

Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study. (2/3580)

OBJECTIVE: To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. METHODS: A double blind, randomised placebo controlled study comparing cyclic etidronate and placebo during two years in 37 postmenopausal women receiving long term corticosteroid treatment, mainly for polymyalgia rheumatica (40% of the patients) and rheumatoid arthritis (30%). Bone density was measured in the lumbar spine, femoral neck, and femoral trochanter. RESULTS: After two years of treatment there was a significant difference between the groups in mean per cent change from baseline in bone density in the spine in favour of etidronate (p = 0.003). The estimated treatment difference (mean (SD)) was 9.3 (2.1)%. Etidronate increased bone density in the spine (4.9 (2.1)%, p < 0.05) whereas the placebo group lost bone (-2.4 (1.6)%). At the femoral neck there was an estimated difference of 5.3 (2.6)% between the groups (etidronate: 3.6% (1.4)%, p < 0.05, placebo: -2.4 (2.1)%). The estimated difference at the trochanter was 8.2 (3.0) (etidronate: 9.0 (1.5)%, p < 0.0001, placebo: 0.5 (2.3)%). No significant bone loss occurred in the hip in placebo treated patients. CONCLUSIONS: Cyclic etidronate is an effective treatment for postmenopausal women receiving corticosteroid treatment and is well tolerated.  (+info)

Dietary isoflavones: biological effects and relevance to human health. (3/3580)

Substantial evidence indicates that diets high in plant-based foods may explain the epidemiologic variance of many hormone-dependent diseases that are a major cause of mortality and morbidity in Western populations. There is now an increased awareness that plants contain many phytoprotectants. Lignans and isoflavones represent two of the main classes of phytoestrogens of current interest in clinical nutrition. Although ubiquitous in their occurrence in the plant kingdom, these bioactive nonnutrients are found in particularly high concentrations in flaxseeds and soybeans and have been found to have a wide range of hormonal and nonhormonal activities that serve to provide plausible mechanisms for the potential health benefits of diets rich in phytoestrogens. Data from animal and in vitro studies provide convincing evidence for the potential of phytoestrogens in influencing hormone-dependent states; although the clinical application of diets rich in these estrogen mimics is in its infancy, data from preliminary studies suggest beneficial effects of importance to health. This review focuses on the more recent studies pertinent to this field and includes, where appropriate, the landmark and historical literature that has led to the exponential increase in interest in phytoestrogens from a clinical nutrition perspective.  (+info)

Walker 256/S carcinosarcoma causes osteoporosis-like changes through ectopical secretion of luteinizing hormone-releasing hormone. (4/3580)

We have shown that Walker 256/S mammary carcinoma caused osteoporosis-like changes in young female rats, accompanied by low serum estradiol and hypercalciuria without changes in the serum levels of calcium, phosphorus, and parathyroid hormone-related peptide. In this study, we investigated the cause of bone loss after Walker 256/S inoculation into female 6-week-old Wistar Imamichi rats, focusing on the sex hormone balance in the host animal. Walker 256/S-bearing rats showed characteristic osteoporosis, with a significant increase in spleen weight and a significant decrease in uterine weight by 14 days after s.c. tumor inoculation. In the in vitro bone marrow culture, mineralized nodule formation ability decreased according to the time after tumor inoculation, and tartrate-resistant acid phosphatase-positive multinucleated cell formation increased at 7 days after tumor inoculation, but it began to decrease at 14 days after tumor inoculation. This indicates that after inoculation with Walker 256/S tumor, the progenitors of osteoblasts and ostroclasts lost their balance in the bone turnover, resulting in bone resorption. On the other hand, Walker 256/S carcinoma expressed luteinizing hormone-releasing hormone (LH-RH) mRNA, and in Walker 256/S-bearing rats, the serum LH-RH level increased significantly from 3 days after tumor inoculation, whereas in the healthy control rats, this level was very low. Consequently, the serum levels of follicle-stimulating hormone, luteinizing hormone, estradiol, and progesterone were significantly lower in the tumor-bearing rats than in the healthy control rats. Because the LH-RH gene is located in the long prolactin release-inhibiting factor (PIF) gene and mRNA amplified by reverse transcription-PCR in this study contained whole LH-RH and a part of PIF, the Walker 256/S tumor is thought to express PIF. Indeed, the serum prolactin level decreased in tumor-bearing rats. The serum level of growth hormone, one of the other pituitary hormones, was not changed. Moreover, the level of an osteolytic cytokine, tumor necrosis factor alpha, increased in the serum of Walker 256/S-bearing rats, although this may be a result of the immune response of the host animal to tumor growth as well as an enlarged spleen. In conclusion, the Walker 256/S tumor lowers estrogen secretion through ectopical oversecretion of LH-RH, and then osteolytic cytokines, such as tumor necrosis factor alpha, increase in tumor-bearing rats, escape the control of estrogen, and activate osteoclasts, resulting in bone loss in a short period.  (+info)

A high incidence of vertebral fracture in women with breast cancer. (5/3580)

Because treatment for breast cancer may adversely affect skeletal metabolism, we investigated vertebral fracture risk in women with non-metastatic breast cancer. The prevalence of vertebral fracture was similar in women at the time of first diagnosis to that in an age-matched sample of the general population. The incidence of vertebral fracture, however, was nearly five times greater than normal in women from the time of first diagnosis [odds ratio (OR), 4.7; 95% confidence interval (95% CI), 2.3-9.9], and 20-fold higher in women with soft-tissue metastases without evidence of skeletal metastases (OR, 22.7; 95% CI, 9.1-57.1). We conclude that vertebral fracture risk is markedly increased in women with breast cancer.  (+info)

Bone densitometry at a district general hospital: evaluation of service by doctors and patients. (6/3580)

OBJECTIVE: To assess doctors' and patients' views about a district general hospital bone densitometry service and to examine existing practice to influence future provision. DESIGN: Three postal surveys: (a) of doctors potentially using the service, (b) of patients undergoing a bone densitometry test during a six month period, and (c) of the referring doctors of the patients undergoing the test. SETTING: Bone densitometry service at South Cleveland Hospital, Middlesbrough and two district health authorities: South Tees and Northallerton. SUBJECTS: All general practitioners (n=201) and hospital consultants in general medicine, rheumatology, obstetrics and gynaecology, orthopaedics, radio therapy and oncology, haematology, and radiology (n=61); all patients undergoing an initial bone densitometry test (n=309) during a six month period; and their referring doctors. MAIN MEASURES: Service awareness and use, knowledge of clinical indications, test results, influence of test results on patient management, satisfaction with the service and its future provision. RESULTS: The overall response rates for the three surveys were 87%, 70%, and 61%. There was a high awareness of the service among doctors and patients; 219(84%) doctors were aware and 155 of them (71%) had used it, and patients often (40%) suggested the test to their doctor. The test was used for a range of reasons including screening although the general use was consistent with current guidelines. Two hundred (65%) bone densitometry measurements were normal, 71(23%) were low normal, and 38(12%) were low. Although doctors reported that management of patients had been influenced by the test results, the algorithm for decision making was unclear. Patients and doctors were satisfied with the service and most (n=146, 68%) doctors wanted referral guidelines for the service. CONCLUSIONS: There was a high awareness of, use of, and satisfaction with the service. Patients were being referred for a range of reasons and a few of these could not be justified, many tests were normal, and clinical decision making was not always influenced by the test result. It is concluded that bone densitometry services should be provided but only for patients whose management will be influenced by test results and subject to guidelines to ensure appropriate use of the technology.  (+info)

Osteoporosis: review of guidelines and consensus statements. (7/3580)

This activity is designed for physicians, pharmacists, nurses, health planners, directors of managed care organizations, and payers of health services. GOAL: To understand current guidelines and consensus statements regarding the prevention, diagnosis, and treatment of osteoporosis. OBJECTIVE: List four national or international organizations involved in the development of consensus statements regarding the prevention, diagnosis, and treatment of osteoporosis. 2. Discuss the significant differences among different countries regarding the prevention and treatment of osteoporosis. 3. List the major risk factors for osteoporosis. 4. Describe the differences in the application of bone mineral density scans, biochemical markers, and ultrasound in evaluating patients with suspected osteopenia and osteoporosis. 5. Distinguish between and briefly discuss therapeutic modalities used in primary prevention, secondary prevention, and treatment of osteoporosis. 6. Discuss the advantages and disadvantages of estrogen/hormone replacement therapy. 7. Describe alternatives to estrogen/hormone replacement therapy.  (+info)

Development and validation of a simple questionnaire to facilitate identification of women likely to have low bone density. (8/3580)

The relationship between low bone mass and risk of fracture is well documented. Although bone densitometry is the method of choice for detecting low bone mass, its use may be limited by the availability of equipment, cost, and reimbursement issues. Improved patient selection for bone densitometry might increase the cost-effectiveness of screening for osteoporosis, a goal we sought to achieve by developing and validating a questionnaire based solely on patient-derived data. Responses to the questionnaire were used to assign postmenopausal women to one of two groups: (1) those unlikely to have low bone mineral density (defined as 2 standard deviations or more below the mean bone mass at the femoral neck in young, healthy white women) and therefore probably not currently candidates for bone densitometry; and (2) those likely to have low bone mineral density and therefore probably candidates for bone densitometry. We asked community-dwelling perimenopausal and postmenopausal women attending one of 106 participating multispecialty centers (both academic and community based) to complete a self-administered questionnaire and undergo bone density measurement using dual x-ray absorptiometry. We used regression modeling to identify factors most predictive of low bone density at the femoral neck in the postmenopausal group. A simple additive scoring system was developed based on the regression model. Results were validated in a separate cohort of postmenopausal women. Data were collected from 1279 postmenopausal women in the development cohort. Using only six questions (age, weight, race, fracture history, rheumatoid arthritis history, and estrogen use), we achieved a target of 89% sensitivity and 50% specificity. The likelihood ratio was 1.78. Validation in a separate group of 207 postmenopausal women yielded 91% sensitivity and 40% specificity. Assuming population characteristics similar to those of our development cohort, use of our questionnaire could decrease the use of bone densitometry by approximately 30%. Sensitivity and specificity can be varied by changing the level for referral for densitometry to provide the most cost-effective use within a particular healthcare setting. Thus use of our questionnaire, an inexpensive prescreening tool, in conjunction with physician assessment can optimize the use of bone densitometry and may lead to substantial savings in many healthcare settings where large numbers of women require evaluation for low bone mass.  (+info)

TY - JOUR. T1 - Comparison of the male osteoporosis risk estimation score (MORES) with frax in identifying men at risk for osteoporosis. AU - Cass, Alvah R.. AU - Shepherd, Angela. AU - Asirot, Rechelle. AU - Mahajan, Manju. AU - Nizami, Maimoona. PY - 2016/7/1. Y1 - 2016/7/1. N2 - PURPOSE We wanted to compare the male osteoporosis risk estimation score (MORES) with the fracture risk assessment tool (FRAX) in screening men for osteoporosis. METHODS This study reports analysis of data from the Third National Health and Nutrition Examination Survey (NHANES III), a nationally representative sample of the US population, comparing the operating characteristics of FRAX and MORES to identify men at risk for osteoporosis using a subset of 1,498 men, aged 50 years and older, with a valid dual-energy x-ray absorptiometry (DXA) scan. DXA-derived bone mineral density using a T score of -2.5 or lower at either the femoral neck or total hip defined the diagnosis of osteoporosis. Outcomes included the ...
Management of glucocorticoid-induced osteoporosis: prevalence, and emerging treatment options Juraj Payer, Kristina Brazdilova, Peter Jackuliak5th Department of Internal Medicine, Medical Faculty of Comenius University and Faculty Hospital Bratislava, Bratislava, SlovakiaAbstract: An excess amount of glucocorticoids represents the primary and most frequent etiological factor influencing secondary osteoporosis. Patients receiving glucocorticoids, but also those with the endogenous form of hypercorticism, are at high risk for the loss of bone density, with the subsequent occurrence of pathological fractures. In this review, we summarize the currently available methods of prevention and the treatment of glucocorticoid-induced osteoporosis. We also include a proposal for both a prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids.Keywords: glucocorticoid-induced osteoporosis, bone mineral density, osteoporotic fractures, calcium and
1) Primary osteoporosis. This is the most common type and affects both men and women over a certain age. Its causes are diverse and may range from hormonal problems to poor dietary habits and lack of physical activity. For more information on the subject, you can read the article on osteoporosis causes.. 2) Secondary osteoporosis. This occurs either as a result of another disease (hyperthyroidism, for example) or as a result of the medication taken to treat another disease. Prolonged use of certain medication is known to lead to side effects such as low bone mineral density and increase the risk of osteoporosis.. 3) Juvenile osteoporosis. Although rare, this type of osteoporosis affects children during their growth period and may have to do with low bone formation rates or fast bone resorption rates. Any significant growth spurt occurring in between 8 and 18 years of age can trigger osteoporosis onset.. 4) Osteogenesis imperfecta. This is also a rare occurrence. It is a type of osteoporosis that ...
Indonesian postmenopausal women face the same osteoporosis risk factors as do women in the West. But are there any differences that make having a localized research study necessary? - Osteoporosis risk factors in Indonesian women - Menopause at BellaOnline
Report of the Senate Ad Hoc Committee on Osteoporosis November 2004 Committee Members Senator Toni Hellon, Chair Senator Robert Cannell Ms. Jane Canby Ms. Renea Gentry Dr. Jeffrey Lisse Dr. Timothy Lohman Ms. Margie Tate Ms. Terri Verason RECEIVED OCT 2 3 2004 ,-SPEAKERS OFfiCE Report ofthe Senate Ad Hoc Committee on Osteoporosis INTRODUCTION This report summarizes the efforts of the Senate Ad Hoc Committee on Osteoporosis. This report is being submitted to the Governor, the Speaker of the House of Representatives and the President ofthe Senate. PURPOSE The Senate Ad Hoc Committee on Osteoporosis, established by the President of the Senate on December 2, 2002, was charged with the following: (1) Research and collect information on osteoporosis; (2) Evaluate the various approaches used by the state and local governments to increase public awareness ofthe risk, treatment and prevention ofosteoporosis; (3) Identify areas where public awareness, public education, research and coordination about ...
Medline Abbreviated Title: Osteoporos Int, OSTEOPOROSIS INT, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA., Osteoporosis International : with other metabolic bone diseases, Osteoporosis International: With other Metabolic Bone Diseases, OSTEOPOROSIS INTERNATIONALWITH OTHER MET ...
This page provides relevant content and local businesses that can help with your search for information on Osteoporosis Prevention Resources. You will find informative articles about Osteoporosis Prevention Resources, including Preventing Osteoporosis. Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Bend, OR that can help answer your questions about Osteoporosis Prevention Resources.
Osteoporosis was first discovered by John Hunter, British surgeon, in 1800s. Osteoporosis may be classified as primary or secondary, based on etiology; while, it is divided in to osteopenia, osteoporosis, and severe osteoporosis, based on disease severity. Osteoporosis occurs as result of an imbalance between bone resorption and bone formation. Major contributing factors to the development of osteoporosis include estrogen deficiency and aging. These factors might lead to osteoporosis by reactive oxygen species (ROS) mediated damage to osteocytes. Decrease in the capability of autophagy in osteocytes is another important factor which makes them vulnerable to oxidative stress. Genes involved in the pathogenesis of osteoporosis can be categorized in four main groups which include the osteoblast regulatory genes, osteoclast regulatory genes, bone matrix elements genes, and hormone/receptor genes. Osteoporosis must be differentiated from other diseases associated with a decrease in bone mineral ...
To determine if a patient has glucocorticoid-induced osteoporosis, you can measure the bone mineral density (BMD) at different parts of the patients body, such as the spine and hip. Dual energy X-ray absorptiometry (DXA) is currently the best test to measure BMD. The test is quick and painless; it is similar to having an X-ray taken, but uses much less radiation. DXA results are scored in comparison to the BMD of young, healthy individuals, resulting in a measurement called a T-score. Patients with T-scores of -2.5 or lower are considered to have osteoporosis and are at a higher risk for a fracture.. According to patient fact-sheet writer Shreyasee Amin, MD, the major goal in the management of glucocorticoid-induced osteoporosis is the prevention of fractures and to help decrease bone loss. At a minimum, she suggests that patients should take 1,000 to 1,500 milligrams of calcium and 400 to 800 IU of vitamin D supplements on a daily basis.. ...
Author(s): Sebastian, Anthony; Frassetto, Lynda A | Abstract: Osteoporosis is a disorder of bone in which the mass of the bone is reduced and the bones architecture at the microscopic level is disordered. Together those abnormalities predispose affected individuals to experience fractures despite only minimal trauma (i.e., fragility fractures). Age related osteoporosis is a common type of osteoporosis that occurs with aging in both men and women usually beginning after the age of peak bone mass. Research has found that the disorder can be partially reversed by reducing the net amount of acid that is produced when consuming typical Western diets. However, the amelioration that results has not been so dramatic or so consistent that physicians have adopted the procedure as part of the standard treatment for age-related osteoporosis. We propose that reducing the net acid load from the diet is not sufficient to reverse age related osteoporosis because it fails to supply base needed to restore the large
UNLABELLED: This paper provides a framework for the development of national guidelines for the management of glucocorticoid-induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer. INTRODUCTION: The need for updated guidelines for Europe and other parts of the world was recognised by the International Osteoporosis Foundation and the European Calcified Tissue Society, which set up a joint Guideline Working Group at the end of 2010. METHODS AND RESULTS: The epidemiology of GIO is reviewed. Assessment of risk used a fracture probability-based approach, and intervention thresholds were based on 10-year probabilities using FRAX. The efficacy of intervention was assessed by a systematic review. CONCLUSIONS: Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment. National guidelines derived from this resource need to be tailored within the national healthcare framework of
Osteoporosis is a disease in which the bones become weak and are more likely to break. According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, 80 percent of the people in the United States with osteoporosis are women. One out of every two women over age 50 will break a bone in their lifetime due to osteoporosis.. People with osteoporosis at high risk for fracture include those that have had an osteoporotic fracture, or have multiple risk factors for fracture; or those who have failed or are intolerant to other available osteoporosis therapy. Prolia works to decrease the destruction of bone and increase bone mass and strength. An injection of Prolia is recommended once every six months.. Due to its prevalence, osteoporosis is a serious concern to public health, said Julie Beitz, M.D., director of the FDAs Office of Drug Evaluation III. The approval of Prolia provides another treatment option for postmenopausal women with osteoporosis who are susceptible to ...
Definition of simple calculated osteoporosis risk estimation in the Financial Dictionary - by Free online English dictionary and encyclopedia. What is simple calculated osteoporosis risk estimation? Meaning of simple calculated osteoporosis risk estimation as a finance term. What does simple calculated osteoporosis risk estimation mean in finance?
This page provides useful content and local businesses that can help with your search for Osteoporosis Treatments. You will find helpful, informative articles about Osteoporosis Treatments, including 5 Tips for Preventing Osteoporosis. You will also find local businesses that provide the products or services that you are looking for. Please scroll down to find the local resources in Gainesville, GA that will answer all of your questions about Osteoporosis Treatments.
Cincinnati--Researchers at the University of Cincinnati Bone Health and Osteoporosis Center are conducting a study to assess the safety and effectiveness of an oral drug on bone health. Although it is more common in post-menopausal women, 10 percent of all men over the age of 50 have enough bone loss that they can be clinically diagnosed as having osteoporosis, said Nelson Watts, MD. Dr. Watts is a UC professor and director of the UC Bone Health and Osteoporosis Center.. The clinical trial will investigate the effectiveness of this medication on preserving bone health in men. In this randomly assigned trial, two thirds of the participants will receive an active medication. One third of the group will receive a placebo. All bone scans and medications are free for qualified participants.. For more information about the male osteoporosis study, call (513) 475-7415. All inquiries are confidential.. ...
Osteoporosis is now recognized as an important public health problem in men. One in three osteoporotic fractures occur in men and the consequences of a fracture in men tend to be more severe than in women. There is now more knowledge about the risk factors and the secondary causes of osteoporosis and fractures in the male population. However, osteoporosis in men still remains under-diagnosed and under-treated. Therapeutic approaches to osteoporosis in men are less well defined than in women. Most of the pharmacologic agents that are currently available, are licensed for use in men on the basis of BMD end points and extrapolation of previous fracture data in women. Drugs now approved for treatment of male osteoporosis in most countries include the anti-resorptive amino-bisphosphonates alendronate, risedronate and zoledronic acid, the anti-resorptive monoclonal antibody denosumab, and the bone-anabolic agent teriparatide. In recent randomized controlled trials most of these compounds were ...
This page provides useful content and local businesses that can help with your search for Osteoporosis Treatment. You will find helpful, informative articles about Osteoporosis Treatment, including Osteoporosis. You will also find local businesses that provide the products or services that you are looking for. Please scroll down to find the local resources in Buckhannon, WV that will answer all of your questions about Osteoporosis Treatment.
This page provides useful content and local businesses that can help with your search for Osteoporosis Treatment. You will find helpful, informative articles about Osteoporosis Treatment, including Osteoporosis. You will also find local businesses that provide the products or services that you are looking for. Please scroll down to find the local resources in Chaska, MN that will answer all of your questions about Osteoporosis Treatment.
There are no data on the use of denosumab in steroid induced osteoporosis. Postmenopausal women with chronic use of Glucocorticoid (GCs) are at high-risk of osteoporotic fractures. Despite bisphosphonate treatment, a certain proportion of high-risk patients using chronic GCs either do not achieve a satisfactory gain in bone mineral density (BMD) or develop new fragility fractures. Thus, more potent osteoporosis treatment is necessary for this subgroup of patients. This prompts the current study which aims to examine the efficacy of denosumab in current users of oral bisphosphonates for Glucocorticoid-induced Osteoporosis (GIOP ...
Osteoporosis is a disease that affects the bones. As the bones start loosing their usual density they become weaker & are more likely to break. Studies have shown that every one in two women & every one in four men above the age of 50 tend to break bones due to osteoporosis. It can cause serious complications & appropriate measures must be taken to avoid extreme consequences.. There is no exact cure for osteoporosis. The idea of the osteoporosis treatment process is to strengthen the bones in order to protect them. The treatment primarily consists of a combination of drugs and suitable lifestyle changes that help in minimising the rate of bone resorption.. Preventive measures include a modification in the general lifestyle factors, doing more muscle-strengthening exercises and ensuring adequate intake of calcium and vitamin D.The medications used for osteoporosis treatment are anti-resorptive agents. Osteoporosis occurs when the rate of resorption in the bones overtakes the rate of bone ...
Clinicians guide to prevention and treatment of osteoporosis. National Osteoporosis Foundation website. Available at: https://www.nof.org/prevention/. Updated 2013. Accessed June 22, 2018.. Diagnosis information. National Osteoporosis Foundation website. Available at: https://www.nof.org/patients/diagnosis-information. Accessed June 22, 2018.. Ho-Pham LT, Nguyen ND, Nguyen TV. Effect of vegetarian diets on bone mineral density: a Bayesian meta-analysis. Am J Clin Nutr. 2009;90(4):943-950.. Khosla L, Melton LJ. Clinical practice: osteopenia. N Engl J Med. 2007;356(22):2293-2300.. Osteoporosis. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T113815/Osteoporosis . Updated February 1, 2018. Accessed June 22, 2018. Osteoporosis causes and risk factors. EBSCO DynaMed Plus website. Available at: http://www.dynamed.com/topics/dmp~AN~T902594/Osteoporosis-causes-and-risk-factors . Updated May 9, 2018. Accessed June 22, 2018. Osteoporosis tests. Ortho Info-American Academy ...
Osteoporosis is a disease that affects roughly 10 million Americans, according to statistics from the National Osteoporosis Foundation. Additionally, another 44 million people are at an increased risk of developing the disease due to of low bone density. Symptoms appear in more than one-third of women over the age of 65. Fractures, pain, and mobility limitations can occur from osteoporosis. Understanding the signs and symptoms, as well as prevention methods, can decrease your chance of developing osteoporosis.. What is Osteoporosis?. Osteoporosis is a disease that decreases bone density and weakens bones. Many people are unaware that they have this disease, and only catch it after an injury. Bone fractures can greatly diminish your quality of life through persistent discomfort and limited mobility.. Oral Health Linked to Osteoporosis. If you suffer from osteoporosis, your oral health is also at risk. Your jawbone may begin to weaken, leading to significant oral health complications. A routine ...
Osteoporosis is a very prevalent condition, affecting millions of adults.. Osteoporosis occurs when the bones become thin and weakened, often as a natural part of aging. This is because as bones age, bone breaks down and absorbs faster than new bone forms.. Most individuals will experience osteoporosis after age 60, but it can happen at any age.. Women who have gone through menopause are at an increased risk for developing osteoporosis due to the decline in estrogen levels. Estrogen protects bone mass, and the reduction of the hormone post-menopause can cause bone loss.. Women age 65 and older should have a dual energy X-ray absorptiometry (DEXA) scan to screen for osteoporosis.. Osteoporosis is called the silent disease because most patients with osteoporosis wont exhibit any symptoms until they break a bone.. Individuals with osteoporosis are at high risk of developing broken bones (fractures), even with minimal trauma.. Fractures that develop with minimal trauma due to weakness and thinned ...
Alendronate, risedronate, zoledronic acid, denosumab, and teriparatide reduce the risk of vertebral and nonvertebral fractures among postmenopausal women with osteoporosis. Ibandronate and raloxifene reduce the risk of vertebral but not nonvertebral fractures. Alendronate, risedronate, zoledronic acid, and denosumab prevent hip fractures among postmenopausal women with osteoporosis. Risedronate decreases the risk of vertebral and nonvertebral fracture among men with osteoporosis.. Among those treated with glucocorticoids, fracture risk reduction was demonstrated for risedronate and alendronate compared to placebo; and for teriparatide compared to alendronate.. Few studies have compared osteoporosis therapies head-to-head.. Adherence to pharmacotherapy is poor in patients with osteoporosis, as with other chronic conditions. Many factors affect adherence to medications, including dosing frequency, side effects of medications, knowledge about osteoporosis, and cost. Age, prior history of fracture, ...
Fractures associated with osteoporosis are expected to rise to 3 million by 2025 with a cost of $25 billion in medical costs. Many of these fractures could be avoided through preventive measures, such as improved implementation of fall reduction strategies and use of effective medications. While medications can significantly reduce the chance of fractures among adults with osteoporosis, alarmingly few at-risk adults use osteoporosis treatments regularly. Only 10% to 30% of at-risk adults ever initiate osteoporosis medications, and of those, only 40% to 50% continue to fill their prescriptions after 1 year. There is a clear need to develop ways for improving adherence with osteoporosis medication regimens. The purpose of this study is to evaluate a telephone coaching program, with or without helpful adherence notifications to doctors, in improving treatment adherence in older adults who are starting an osteoporosis medication.. Participation in this study will last 1 year. Through random ...
BACKGROUND AND PURPOSE: Glucocorticoid-induced osteoporosis (GIO) is the leading cause of secondary osteoporosis. Clinical evidence suggests a role for genistein aglycone in the treatment of post-menopausal osteopenia although proof of efficacy in comparison with currently available treatments is still lacking. To clarify this issue, we investigated the effects of genistein on bone compared with alendronate in experimental GIO. EXPERIMENTAL APPROACH: A total of 28 female Sprague-Dawley rats were used. GIO was induced by daily injections of methylprednisolone (MP; 30 mg x kg(-1) s.c.) for 60 days. Sham GIO animals (Sham-MP) were injected daily with the MP vehicle. At the end of the osteoporosis development period, MP rats were randomized to receive: vehicle (n= 7), genistein aglycone (5 mg x kg(-1) s.c.; n= 7) or alendronate (0.03 mg x kg(-1) s.c.; n= 7). Treatment lasted 60 days. Sham-MP animals were treated with vehicle for an additional 60 days. At the beginning and at the end of treatments, ...
Osteoporosis is caused by the bones losing density, and this can be due to a variety of issues. The bones of the body are a living tissue that is constantly being broken down and built up again. A special form of bone cell, osteoclasts break down bone cells that are damaged, and osteoblasts, a different type of cell, build up new bone tissue. Bones are never solid, but as osteoporosis sets in, the bones develop larger spaces between clusters of tissue. In secondary osteoporosis, this loss of density is due to a diagnosed medical condition, including bone marrow disease, inflammatory disorders, endocrine diseases, or taking certain corticosteroids. In primary osteoporosis, the relationship between osteoclasts and osteoblasts gradually gets off balance as people age, and they lose bone density without a medical condition. Certain levels of hormones and nutrients tend to contribute to primary osteoporosis. If a person does not have enough calcium for essential bodily functions, the body will leach ...
Osteoporosis management is suboptimal even for high-risk people with a history of prior fracture. There is also evidence that individuals with moderate trauma fracture have a lower bone density and are at higher risk of subsequent fracture. This study aimed to define factors influencing the management of individuals at risk for osteoporosis and to examine the risk profiles of individuals with minimal and moderate trauma fractures. Consecutive fracture patients (n =218) treated in the outpatient fracture clinic in St Vincents Hospital, Sydney, over a 15-month period (February 2002-July 2003) were interviewed. Fracture risk factors, prior investigation and treatment for osteoporosis were collected and participants were contacted after 3 months to ascertain follow-up. Risk factors for osteoporosis including family history, low dietary calcium and conditions associated with bone loss were similar between low- and moderate-trauma groups and between sexes. Even though half of participants had had a prior
We, Kaykay Industries is one of the prominent leading Manufacturer and Supplier of femur & vertebrae osteoporosis model, We keep quality standards of femur & vertebrae osteoporosis model high through effective application of quality control system based In Dabri Palam Road, New Delhi, India
The Osteoporosis Prevention and Treatment Center specializes in the prevention, diagnosis and treatment of osteoporosis and metabolic bone disease, including postmenopausal osteoporosis, male osteoporosis, osteopenia induced by glucocorticoids, anticonvulsants and excess thyroid hormone; Pagets disease, hypercalcemia of malignancy, and hyperparathyroidism.
The herbs used in TCM are known for their many therapeutic properties. To investigate their potential in preventing osteoporotic fractures, Taiwanese researchers conducted a nationwide, population-based cohort study. They identified osteoporosis cases and selected a comparison group that was frequency-matched according to sex, age (per five years), diagnosis year of osteoporosis, and index year. They also estimated the difference between the two groups in terms of the development of fracture using the Kaplan-Meier method and the log-rank test.. After the insertion of age, gender, urbanization level, and comorbidities into the Coxs proportional hazard model, the researchers found that the patients who used TCM had a lower hazard ratio of fracture compared to those who did not use TCM. Based on the Kaplan-Meier curves, they also reported that osteoporosis patients who used TCM had a lower incidence of fracture than those who did not. In addition, the researchers observed that patients who used ...
May is Osteoporosis Awareness and Prevention Month, people are encouraged to understand the risk factors associated with this condition. Preventative measures which promote healthy bones include sufficient calcium intake, achieving adequate levels of vitamin D, and performing bone healthy exercises. The aim of National Osteoporosis Awareness and Prevention Month is to promote good bone health through the prevention, detection and treatment of osteoporosis.. Osteoporosis is more common in women than in men; approximately 80% of osteoporosis cases are in women. Women are often the main focus of these awareness campaigns as are people with a family history of osteoporosis. Teenage girls are encouraged to build strong bones while they are still developing. The consequences of weak bones later in life can be serious. Building strong bones during this crucial development stage includes eating foods high in calcium and vitamin D, eating fruits and vegetables every day, and regular exercise. During ...
NorthShore encourages patients to utilize our medical library. Read our Osteoporosis Risk Factors encyclopedia resources online.
The options available for effective osteoporosis treatment continue to grow. Because of the large number of treatment options, many clinicians, particularly in primary care, are uncertain about when to start therapy, which drug to use, and when to stop. The issue of when to stop antifracture therapy is now front and center as evidence accumulates that the antifracture benefits of some treatments persist after discontinuation and as patients increasingly voice concerns about possible rare but serious problems linked to osteoporosis treatment, such as atypical femoral fractures, osteonecrosis of the jaw, arrhythmias, and cancer. The decision about when to stop or change osteoporosis treatment is particularly complex and should be influenced by the expected benefits and harms of continued use and at least some information about what to expect after therapy is stopped (also known as resolution-of-effect). A prolonged skeletal resolution-of-effect, characteristic of at least some bisphosphonates, might be
May 17, 2004. Strontium ranelate can prevent both hip and vertebral fractures in women over 70 years old, researchers reported this week at the IOF World Congress on Osteoporosis in Rio de Janeiro (conference abstract OC 39).. Women in this age bracket have an elevated risk of sustaining hip fractures, which have been shown to increase mortality at the rate of 15 to 30 percent, mostly within the first six months after the fracture. Data show that two grams of strontium ranelate, taken daily, can reduce the risk of hip fractures in this subpopulation by 36%, and vertebral fractures by up to 59%.. The bone-saving properties of strontium ranelate were evaluated in two randomized, double-blind, placebo controlled trials. The five-year TROPOS (TReatment Of Peripheral OSteoporosis) study was designed to evaluate the efficacy of the drug in treating peripheral fractures, while the Spinal Osteoporosis Therapeutic Intervention (SOTI) study was designed to assess the drugs ability to reduce new vertebral ...
Osteoporosis is a progressive condition in which bone density is lost, or there is insufficient bone formation, thereby weakening the bones and making them more susceptible to fractures. Although much more common in older adults, especially women in menopause and after, osteoporosis can also occur during childhood. Most often, osteoporosis during childhood is caused by an underlying medical condition (the disease is then called secondary osteoporosis) or a genetic disorder (such as osteogenesis imperfecta). However, sometimes, no cause can be found and the disease is categorized as a very rare form of osteoporosis, called idiopathic juvenile osteoporosis (IJO).. ...
Osteoporosis is a progressive condition in which bone density is lost, or there is insufficient bone formation, thereby weakening the bones and making them more susceptible to fractures. Although much more common in older adults, especially women in menopause and after, osteoporosis can also occur during childhood. Most often, osteoporosis during childhood is caused by an underlying medical condition (the disease is then called secondary osteoporosis) or a genetic disorder (such as osteogenesis imperfecta). However, sometimes, no cause can be found and the disease is categorized as a very rare form of osteoporosis, called idiopathic juvenile osteoporosis (IJO).. ...
The launch of the National Osteoporosis Societys Message to My Younger Self campaign generated extensive press coverage this week, highlighting crucial messages to millions of people across the UK about the importance of healthy eating for strong bones.. Our story - which warned that current eating habits of teenagers and young adults could cause bone health problems in later life - was reported across the UK media, with some reports focusing on the dangers of diets which cut out some food groups such as dairy products.. This element of some of the reports generated a great deal of interest, particularly across the charitys social media channels.. Responding to the issues raised over the role dairy plays in bone health, National Osteoporosis Society Clinical Director Fizz Thompson said the charitys main message was to eat a healthy balanced diet including calcium for strong bones in all its forms.. Dairy is just one way to get good amounts of calcium; its not better absorbed or preferable ...
Although physicians may be familiar with osteoporosis, a systemic skeletal disease that leads to increased bone fragility, there may not always see the significance of the disease. Unfortunately, the disease remains an underdiagnosed and undertreated disease. And there often is a disconnect between the patient who has a fracture and someone recognizing that there may well be an underlying disease or problem - namely osteoporosis - that has led to the increased risk for fracture and a fracture occurring. |br /||br /|In this episode of Physician's Weekly, Peter Hofland, Ph.D. talks with Andrea Singer, MD, FACP, CCD, is the Chief Medical officer of the National Osteoporosis Foundation (NOF) about osteoporosis and the results of a recently published report that provides national and state-level insights into the economic and health impact of osteoporotic fractures on Medicare Fee for Service beneficiaries and the Medicare program. [1] In addition to her responsibilities at the National Osteoporosis
Prednisone and other steroids are used to treat many conditions, but they may also cause serious side effects such as steroid-induced osteoporosis.
How Osteoporosis Could Affect the Way You Practice. Osteoporosis is a condition that can strike even the most health-conscious and vibrant of your patients. Here is what you need to know about the condition.. Osteoporosis is a condition in which bones become thin and less dense over time; as bone mineral density is reduced, the amount and variety of proteins in bone changes and the bone micro-architecture is disrupted.1 In osteoporosis, the bone loss is severe, causing even the normal stress that occurs during sitting, standing, or even coughing to cause unexpected fractures. As a result, it is not uncommon for someone with osteoporosis to struggle with chronic pain, immobility, disability, loss of independence, and a lower quality of life.2,3. What Are the Symptoms?. Osteoporosis occurs stealthily over several years with no visible signs. Often, the first sign of osteoporosis is a painful fracture that needs medical care. The bones most susceptible to fracture are the spine, hip, rib, or ...
The evaluation and treatment of osteoporosis differ depending on several conditions such as the associated risk factors for the development of osteoporosis and fragility fractures, gender, age and menopausal status of the individual, and the presence of other secondary associated processes, among others. In addition, some types of secondary osteoporosis, such as glucocorticoid induced osteoporosis, present fractures with relatively higher bone mineral density values, whereas other metabolic bone diseases, such as osteomalacia, can easly be misdiagnosed with this condition. All these data should be taken into account when evaluating the diagnosis and treatment of these patients. Besides general measures, the pharmacological management of osteoporosis, including the type of antiosteoporotic drug, administration route, optimal treatment duration and monitoring, depend on the characteristics of the patient, the fracture risk and the type of treatment. Thus, whereas bisphosphonates are commonly used ...
Osteoporosis is severely impaired bone strength resulting in skeletal fragility. This stage of compromised bone health increases the risk of potentially life-threatening bone fractures from falls. Statistics released by the Agency for Healthcare Research and Quality indicate that one in five women who break a hip will die within a year. In the most severe cases of osteoporosis, bones are so brittle, even a sneeze can break a rib.. Masters swimmers can reduce osteoporosis risk by complementing swim workouts with weight-bearing activities, such as brisk walking and weight training. Individuals already diagnosed with osteoporosis should use caution at the pool to avoid impact and fall-related injuries.. The National Osteoporosis Foundation recommends that people with compromised bone health avoid forward bending from the waist and twisting the spine to the point of strain. Diving off the blocks is one example of a potentially hazardous forward flexion activity.. For this reason, swimmers with ...
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Osteoporosis is a major health threat in the United States, particularly among people older than 50 years of age. Estimates indicate that 10 million Americans have osteoporosis, and another 34 million are at risk of developing osteoporosis due to low bone mass. Although women are more at risk of developing the condition (80% of patients with osteoporosis are women), all people older than 50 should be concerned about prevention, because studies indicate that 55% of Americans older than 40 exhibit signs of low bone mass. The best way to fight osteoporosis is with early intervention - ideally in the form of a calcium-rich diet and weightbearing exercise. Men younger than 65 and premenopausal women should be getting 1000 mg of calcium a day, and men and women aged 65 and older should be getting a daily dose of 1500 mg. The problem is that most people do not consume a diet of the dairy products, leafy green vegetables, fish, and tofu that delivers adequate levels of calcium. Thus, many patients are ...
Highlights from the 2014 World Congress on Osteoporosis held in Seville, Spain. Professor Roger Fielding gives and overview of sarcopenia and the increased importance of muscle at the WCO. Professor Maria-Luisa Brandi gives an introduction to skeletal rare disorders and why osteoporosis professionals should pay attention to these diseases.. ...
Osteoporosis is a major public health threat for an estimated 44 million Americans, or 55 percent of the people 50 years of age and older. In the U.S., 10 million individuals are estimated to already have the disease and almost 34 million are estimated to have low bone mass, placing them at increased risk for osteoporosis. By the year 2010, it is estimated that over 52 million women and men in this same age category will be affected, and if current trends continue, the figure will climb up to over 61 million by 2020 according to the National Osteoporosis Foundation.. Being Asian is a risk factor for osteoporosis. Having a thin, small boned frame (or low bone mass), low physical activity and low calcium intake also are risk factors. As much as 90% of Asian Americans may be lactose intolerant, therefore obtaining calcium from dairy products proves problematic. As a result of osteoporosis, vertebral or spinal fracture occurrence is high among Asian American women.. ...
It is important to speak to your healthcare provider to find out when a BMD test is appropriate for you. Your healthcare provider will consider your risk factors for osteoporosis (such as your age, medical history including your history of broken bones, your parental history of osteoporosis and/or fracture, and more) when deciding on the right time for you to have a BMD test.. The NYSOPEP Osteoporosis Risk Assessment for Postmenopausal Women is a tool that you can use to identify your personal risk factors for osteoporosis. The completed assessment should be discussed with your healthcare provider. The tool can be used to empower your discussion with your healthcare provider about how to reduce your risks for osteoporosis and help your healthcare provider decide when a BMD test is right for you. Although risk factors may increase your likelihood of getting osteoporosis, having risk factors does not mean that you have or will get the disease. A BMD test is the only way to diagnose ...
ABSTRACT. The term metabolic bone disease encompasses an unrelated group of systemic conditions that impact on skeletal collagen and mineral metabolism. Their asymptomatic progression leads to advanced skeletal debilitation and late clinical manifestation. This article provides a brief overview of advances in the understanding of the pathogenesis of rickets, osteomalacia and age-related osteoporosis.. ...
If youre nearing 60, you have some pretty good company. Actress Sally Field, the seemingly ageless icon of a Baby Boom generation that starts turning 60 this year, has revealed that she has osteoporosis and is leading a public action campaign to inspire women to fight the fragile bone disease. Surprised by her recent diagnosis of osteoporosis, Field chose to go public with her personal health and is launching Rally With Sally For Bone HealthSM, sponsored by Roche and GlaxoSmithKline. The campaign encourages women with osteoporosis to protect themselves against fractures so they can remain active and reduce their risk of a debilitating injury.. Osteoporosis is a condition in which bones become weaker, more brittle and susceptible to fractures. One in two women over age 50 will suffer an osteoporosis-related fracture in her lifetime, which can result in significant pain and loss of height and may possibly cause some women to lose their ability to dress themselves, stand up and even walk. It can ...
Marcus R, Feldman D, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... osteoporosis, pathological fractures, decrease of muscle mass and tone, progressive anaemia, asthenia, and depression) (Tyrrell ... in rat models of osteoporosis". Biol. Pharm. Bull. 26 (11): 1563-9. doi:10.1248/bpb.26.1563. PMID 14600402. Nagata N, Miyakawa ...
"Our People , Osteoporosis". osteoporosis.org.nz. Retrieved 27 March 2019. "ANZBMS - Office Bearers and Council". www.anzbms.org ... "Our People". Osteoporosis. Retrieved 2 March 2018. "Staff". Cmdt.org.nz. Retrieved 2 March 2018. "Documents The Lens - Free & ... Osteoporosis New Zealand Australia and New Zealand Bone and Mineral Society International Society of Bone Morphometry ...
"Osteoporosis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. El-Najjar M and Robertson Jr AL. 1976. Spongy ... Osteogenesis imperfecta Osteomalacia Osteomyelitis Osteopenia Osteopetrosis Osteoporosis Porotic hyperostosis Primary ...
... osteoporosis; marfanoid habitus; and scoliosis, kyphosis, or both (kyphoscoliosis). Distinctive facial features include a cleft ...
ISBN 978-1-84214-263-9. Robert Marcus; David W. Dempster; Jane A. Cauley; David Feldman (13 June 2013). Osteoporosis. Academic ...
... most commonly occurs bilaterally as a result of spinal osteoporosis. Osteoporosis is a condition ... The most common fractures that occur due to osteoporosis is in the hip or vertebrae, resulting in a loss of space between the ... It is estimated that osteoporosis can cause 25% of females over 50 years of age within the United States to have at least one ... It may occur unilaterally due to conditions such as scoliosis, or bilaterally due to conditions such as osteoporosis and ...
The risk of osteoporosis and serious bone fractures with bicalutamide monotherapy appears to be no different than with non-use ... However, due to the loss of estrogen, bone loss will accelerate and the risk of osteoporosis developing with long-term therapy ... Feldman D, Marcus R, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... osteoporosis, and frailty). According to Iversen et al. (2006), the increased non-prostate cancer mortality with bicalutamide ...
"Osteoporosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. August 2014. Retrieved 16 May 2015. ... Bonjour, J. -Ph; Theintz, G; Law, F; Slosman, D; Rizzoli, R (1994). "Peak bone mass". Osteoporosis International. 4: 7-13. doi: ... this time males typically undergo a longer bone maturation period than women which is why women are more prone to osteoporosis ...
Osteoporosis is defined by the National Institutes of Health as ''a skeletal disorder characterized by compromised bone ... Osteoporosis. 2006. National Institutes of Health. Retrieved on 2007-10-24. Ott, Susan. 2007. Estrogen: Mechanism of Bone ... Patients with RED-S get osteoporosis due to hypoestrogenemia, or low estrogen levels. With estrogen deficiency, the osteoclasts ... Low energy availability with or without eating disorders, functional hypothalamic amenorrhea, and osteoporosis, alone or in ...
Marcus R, Feldman D, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... bicalutamide monotherapy is not associated with decreased bone mineral density or osteoporosis. Conversely, bicalutamide ...
However, osteoporosis is essentially the result of a lack of new bone formation in combination with bone resorption in reactive ... With oral osteoporosis, the emphasis should be on good nutrient absorption and metabolic wastes elimination through a healthy ... Heavy metals such as lead and cadmium have been implicated in osteoporosis. Cadmium and lead promotes the synthesis of ... In cases of advanced oral ischaemic osteoporosis and/or ONJ that are not bisphosphonates related, clinical evidence has shown ...
Cooks, A. M. (1955). "Osteoporosis". The Lancet. 265 (6871): 929-937. doi:10.1016/S0140-6736(55)90963-6. PMID 14368910. Jones, ...
"Osteoporosis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. staff, familydoctor org editorial. "What Is ... osteoporosis osteopenia osteomalacia brown tumor should be considered as the top-line diagnosis if a mass-forming lesion is ...
Szulc P, Seeman E, Delmas PD (2000). "Biochemical measurements of bone turnover in children and adolescents". Osteoporosis ... Value of the study of total alkaline phosphatases and bone isoenzyme in a population of subjects with osteoporosis]". Annales ... Biliary obstruction Bone conditions Osteoblastic bone tumors Osteomalacia Osteoporosis Hepatitis Cirrhosis Acute cholecystitis ...
"Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians". Osteoporosis ... Studies have also linked mutations in the VPS13B gene to osteoporosis. An association between an increase of the VPS13B copy ...
In addition, bone density measurement may be performed to evaluate for osteoporosis. When a tumor is suspected as the ... Compression fractures which develop gradually, such as in osteoporosis, may initially not cause any symptoms, but will later ... 2011). "Balloon kyphoplasty and vertebroplasty in the management of vertebral compression fractures". Osteoporosis ... Osteoporosis International. 16 (10): 1281-90. doi:10.1007/s00198-004-1798-8. PMID 15614441. S2CID 34208503. Taylor, Rod S.; ...
... is the first quantitative analysis method used in the diagnosis of osteoporosis. To evaluate bone ... Osteoporosis International. 5 (5): 377-381. doi:10.1007/bf01622260. ISSN 0937-941X. PMID 8800788. S2CID 11127198. Meema, Erik H ... invented by Cameron and Sorenson was the first quantitative analysis method applied to the diagnosis of osteoporosis. This ... simple and sensitive method for early diagnosis and prevention of osteoporosis. Generally speaking, the single photon ...
Hamrick MW, Ferrari SL (July 2008). "Leptin and the sympathetic connection of fat to bone". Osteoporosis International. 19 (7 ... and osteoporosis. Other rare polymorphisms have been found but their association with obesity are not consistent. A single case ... "Association of polymorphisms in the leptin and leptin receptor genes with inflammatory mediators in patients with osteoporosis ...
"Osteoporosis Overview , NIH Osteoporosis and Related Bone Diseases National Resource Center". www.bones.nih.gov. Retrieved 7 ... Osteoporosis is a type of bone disease characterized by a loss of bone density, mass and architecture that leaves a patient ... The prevalence of osteoporosis in patients with SLE varies geographically and some attribute it to BMD and T-score diagnostic ... Exogenous corticosteroids induce osteoporosis by increasing bone resorption and reducing bone formation. Bone loss can be ...
... osteoporosis, back pain, diabetes, depression and other mental illnesses and falls in the elderly. Exercise has been shown to ... Osteoporosis International. 33 (7): 1415-1427. doi:10.1007/s00198-022-06357-3. PMC 8881760. PMID 35218402. Hayden, JA; Ellis, J ...
Osteoporosis International. 20 (4): 537-42. doi:10.1007/s00198-008-0729-5. PMC 2651998. PMID 18766292. Wickwire EM, Geiger- ...
As a common bone disorder, osteoporosis affects a large section of the population, resulting in a reduced quality of life, ill ... Office of the Surgeon General (US). "Medications that can Cause Bone Loss, Falls and/or Fractures , Osteoporosis Canada". 4 ... These consist of genetic diseases, osteoporosis, infections of the bone, and Paget's disease of bone. Neuromotor impairments ... "Medical Conditions that can Cause Bone Loss, Falls and/or Fractures , Osteoporosis Canada". 4 October 2017. Retrieved 2020-06- ...
Some diseases with symptoms of decreased bone density are osteoporosis, and rickets. Some people who experience increased bone ... Osteoporosis International. 20 (9): 1529-1538. doi:10.1007/s00198-009-0836-y. ISSN 1433-2965. PMID 19238309. S2CID 11502836. ... prolonged ethanol exposure increases fracture risk by decreasing bone mineral density and promoting osteoporosis. Indirect ... adding weight-bearing exercise versus nonweight bearing programs to the medical treatment of elderly patients with osteoporosis ...
Prevention and treatment of female osteoporosis Treatment of male osteoporosis Prevention and treatment of corticosteroid- ... "Severe Pain with Osteoporosis Drugs". FDA Patient Safety News. March 2008. Archived from the original on 15 April 2014. " ... Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and ... Lay summary in: Gardner A (December 31, 2008). "Osteoporosis Drug Prompts Increase in Certain Bone Cells". Washington Post. ...
However, this acceptance of the acid-ash hypothesis as a major modifiable risk factor of osteoporosis by these publications was ... This review found no significant evidence suggesting dairy product intake causes acidosis or increases risk for osteoporosis. A ... Consequently, "alkaline ash" (alkaline producing) elements would hypothetically decrease the risk of osteoporosis. This ... including an increased risk of osteoporosis. It has received some attention in the lay community, and has been used to support ...
While working at the University of Hull he led a team applying ultrasound to the diagnosis and monitoring of osteoporosis. This ... Osteoporosis International. 6 (6): 471-479. doi:10.1007/BF01629580. ISSN 0937-941X. PMID 9116393. S2CID 26081955. Scruby, C. B ... led to an ultrasonic index for osteoporosis and the development of commercial ultrasound heel scanners that are available ...
Colazo JM, Hu JR, Dahir KM, Simmons JH (February 2019). "Neurological symptoms in Hypophosphatasia". Osteoporosis International ... September 2017). "Clinical, radiographic and biochemical characteristics of adult hypophosphatasia". Osteoporosis International ... Osteoporosis International. 32 (2): 377-385. doi:10.1007/s00198-020-05612-9. PMC 7838076. PMID 32879991. Zurutuza L, Muller F, ...
August 2002). "Meta-analyses of therapies for postmenopausal osteoporosis. VII. Meta-analysis of calcium supplementation for ... and osteoporosis are the leading causes of morbidity and mortality, as well as impaired quality of life. Among women in all age ... and osteoporosis.[citation needed] In its entirety, the WHI enrolled more than 160,000 postmenopausal women aged 50-79 years ( ... Osteoporosis International. 24 (2): 567-580. doi:10.1007/s00198-012-2224-2. PMC 3557387. PMID 23208074. Chlebowski RT, Johnson ...
"Prednisolone induces osteoporosis-like phenotype in regenerating zebrafish scales". Osteoporosis International. 25 (2): 567-578 ... Bergen, Dylan J. M.; Kague, Erika; Hammond, Chrissy L. (2019). "Zebrafish as an Emerging Model for Osteoporosis: A Primary ...
Osteoporosis International. 20 (9): 1603-11. doi:10.1007/s00198-009-0839-8. PMID 19172341. S2CID 10711802. Kamdem LK, Hamilton ... "Changes of bone formation markers osteocalcin and bone-specific alkaline phosphatase in postmenopausal women with osteoporosis ... well correlated with increases in bone mineral density during treatment with anabolic bone formation drugs for osteoporosis, ...

No data available that match "osteoporosis"


  • Osteoporosis causes bones to become weak and brittle - so brittle that a fall or even mild stresses such as bending over or coughing can cause a fracture. (mayoclinic.org)
  • Osteoporosis is a disease in which bones become fragile and more likely to break (fracture). (medlineplus.gov)
  • Osteoporosis has been diagnosed by a bone density study , whether or not you have a fracture, and your fracture risk is high. (medlineplus.gov)
  • You have had a bone fracture, and a bone density test shows that you have thin bones, but not osteoporosis. (medlineplus.gov)
  • One out of every two women and one in four men over 50 will have an osteoporosis-related fracture in their lifetime. (livescience.com)
  • People may not know they have osteoporosis until their bones become so weak that a bump or fall causes a hip to fracture or a vertebra to collapse. (livescience.com)
  • What's more, few older men are on the alert for osteoporosis, even though one in five will have a fracture. (news24.com)
  • Osteoporosis is sometimes called the "silent disease," and most people don't know they have osteoporosis until it has progressed, often to the point of fracture, usually in the hip, wrist or spine. (spine-health.com)
  • Even when undiagnosed osteoporosis results in a vertebral fracture , the pain is frequently dismissed as general back pain. (spine-health.com)
  • high dietary calcium suppresses age-related bone loss and reduces fracture rate in patients w/ osteoporosis. (wheelessonline.com)
  • Postmenopausal osteoporosis is a silent disease that affects millions of women, making their bones weak and more likely to fracture over time. (news-medical.net)
  • In fact, in the U.S. today, 8 million women are estimated to already have osteoporosis, and almost 27 million more are estimated to have low bone mass, placing them at increased risk for fracture. (news-medical.net)
  • Usually, a person will sustain a fracture before they find out that they suffer from osteoporosis but by that time the disease may be in its advanced stages and the damage may be serious. (com.pk)
  • The bone health specialists at UC San Diego Health help ensure that anyone who incurs a hip fracture as a result of a fall from a standing height or less will receive a fracture risk assessment, treatment (if necessary), and continued care from an orthopedist and osteoporosis specialist. (ucsd.edu)
  • Geriatricians regularly treat osteoporosis since age is the single-greatest risk factor for sustaining an osteoporotic fracture. (ucsd.edu)
  • If you answered "yes" to any of these questions, you need to take the time and read this article as one in every two Caucasian women in the US will experience an osteoporosis-related fracture in her lifetime. (arizonafoothillsmagazine.com)
  • There also are several medications available for treating osteoporosis that can help to rebuild and strengthen bone and reduce fracture risk. (cooperhealth.org)
  • If you are a 50 year-old woman, you have a 50-50 chance of suffering a bone fracture related to osteoporosis during your lifetime. (coxhealth.com)
  • Rationale: The USPSTF found good evidence that the risk for osteoporosis and fracture increases with age and other factors, that bone density measurements accurately predict the risk for fractures in the short-term, and that treating asymptomatic women with osteoporosis reduces their risk for fracture. (uspreventiveservicestaskforce.org)
  • Rationale: The USPSTF found fair evidence that screening women at lower risk for osteoporosis or fracture can identify additional women who may be eligible for treatment for osteoporosis, but it would prevent a small number of fractures. (uspreventiveservicestaskforce.org)
  • Modeling analysis suggests that the absolute benefits of screening for osteoporosis among women aged 60-64 who are at increased risk for osteoporosis and fracture are comparable to those of routine screening in older women. (uspreventiveservicestaskforce.org)
  • In 2012, guidelines published by the Veterans Health Administration (VHA) identified osteoporosis as a major health issue in men because their risk of illness and death following a hip fracture is greater than for women. (thedoctorwillseeyounow.com)
  • A fracture risk of three percent or greater puts a person over the minimum threshold for treatment with vitamin D and bisphosphonates, a class of drugs prescribed for osteoporosis. (thedoctorwillseeyounow.com)
  • The team found that nearly half - 48 percent - of men between the ages of 75 and 79 years old who had only age as a risk factor for osteoporosis had a 10-year hip fracture risk of three percent or greater, making it clear how common osteoporosis is among men. (thedoctorwillseeyounow.com)
  • As the authors write, "There is a need for developing strategies to improve the evaluation and management of osteoporosis in all older men, particularly among those with a very high risk of fracture. (thedoctorwillseeyounow.com)
  • Osteoporosis is a serious problem with 50% of women and 25% of men over the age of 50 suffering a fracture because of it. (thenakedscientists.com)
  • Fracture outcome definitions in observational osteoporosis d. (lww.com)
  • The objective of this review is to describe fracture outcome definitions in observational osteoporosis drug effects studies from Canada and the United States. (lww.com)
  • We will include observational studies from the United States and Canada that consider the impact of osteoporosis pharmacotherapies on fracture risk and leverage health care administrative data. (lww.com)
  • Osteoporosis is a debilitating brittle bone disease characterized by low bone-mineral density and increased fracture risk. (lww.com)
  • 3 Health care administrative databases are commonly used to measure fracture prevalence and to help determine osteoporosis drug effectiveness (eg, on femoral neck, radius/ulna, vertebral fractures) and safety (eg, atypical femoral fracture). (lww.com)
  • Homeopathic preparation used to relieve post fracture pain associated with osteoporosis or traumas. (rediscoverhealth.ca)
  • Having a parent or sibling with osteoporosis puts you at greater risk, especially if your mother or father experienced a hip fracture. (youchoimd.net)
  • One in three women and one in five men will develop a fracture as a result of osteoporosis. (osteoporosis.org.za)
  • Osteoporosis is a disease in which the density and quality of bones are reduced, leading to weakness of the skeleton and increased risk of fracture, particularly of the spine, wrists, hip, pelvis and upper arms. (osteoporosis.org.za)
  • Whether you are already diagnosed with osteoporosis or you are unaware you are at risk, a fracture may well become a reality - sometimes caused by a simple misadventure that in a younger, stronger boned person would not cause a problem. (osteoporosis.org.za)
  • osteoporosis, osteoporotic fracture, osteoporosis management. (healthplexus.net)
  • Many people have no signs of osteoporosis until a fracture has occurred, making it a silent illness. (verywellhealth.com)
  • Osteoporosis is a condition in which the bones become less dense and more likely to fracture. (trellushealth.net)
  • Sometimes a patient's first fracture is the sentinel event that alerts the clinician to an underlying disorder leading to osteoporosis. (medscape.com)
  • Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. (medscape.com)
  • Having low bone mineral density doesn't necessarily mean that you will develop osteoporosis or have a fracture. (aidsmap.com)
  • According to the Osteoporosis Canada, 2 Million Canadians are affected by osteoporosis and at least 1 in 3 women and 1 in 5 men will suffer from an osteoporotic fracture during their lifetime. (medgadget.com)
  • This guideline covers assessing the risk of fragility fracture in people aged 18 and over with osteoporosis. (bvsalud.org)
  • However, simple x-rays of other bones are not very accurate in predicting whether you are likely to have osteoporosis. (medlineplus.gov)
  • Osteoporosis is a systemic disease that gradually weakens the bones, leading to painful and debilitating fragility fractures (broken bones). (news24.com)
  • Osteoporosis is a progressive bone disease that weakens the bones and increases the risk of fractures. (nationaljewish.org)
  • Osteoporosis is a thinning of the bones that causes them to become porous and fragile. (spine-health.com)
  • Osteoporosis is a disease that affects your bones. (healthwise.net)
  • Osteoporosis can lead to broken bones (fractures) in the hip, spine, and wrist. (healthwise.net)
  • Osteoporosis is characterised by low bone mass and loss of bone tissue that leads to weak and fragile bones. (com.pk)
  • Mrs Shahid, a 55-year-old, who has been battling with osteoporosis after her menopause faces great difficulty in walking due to her weak bones. (com.pk)
  • Osteoporosis is defined as: a medical condition in which the bones become brittle and fragile from loss of tissue, typically as a result of hormonal changes, or deficiency of calcium or vitamin D. (arizonafoothillsmagazine.com)
  • The bones most often affected by osteoporosis are the hips, spine and wrists. (cooperhealth.org)
  • Osteopenia is a condition in which your bones are weaker and less dense than normal, but they aren't so brittle that they break easily, as in osteoporosis. (cooperhealth.org)
  • Also known as bone loss or porous bone, Osteoporosis is a well-known condition in which bones become weaker and more susceptible to fractures. (uclahealth.org)
  • Black Bears seem to be unique amongst hibernating animals because they have the unique ability to stop their bones from thinning during their long winter sleep, suggesting that they may hold the key to preventing bone thinning diseases, like osteoporosis, in humans. (thenakedscientists.com)
  • Osteoporosis is a long-term (chronic) disease that slowly weakens bones until they break easily. (comportho.com)
  • The exact role tobacco plays in osteoporosis isn't clearly understood, but it has been shown that tobacco use contributes to weak bones. (youchoimd.net)
  • Osteoporosis is a disease that causes bones to become weak and brittle. (nih.gov)
  • You can take steps to help prevent osteoporosis and broken bones by: Doing weight-bearing exercises, such as walking or dancing, and lifting weights. (nih.gov)
  • Osteoporosis has been called a childhood disease with old-age consequences because building healthy bones in youth helps prevent osteoporosis and fractures later in life. (trellushealth.net)
  • Milk and Osteoporosis - Is Dairy Good for Your Bones? (iytmed.com)
  • Osteoporosis is a progressive illness in which bones deteriorate, losing mass and minerals gradually. (iytmed.com)
  • The name is extremely detailed of the nature of the illness: osteoporosis = porous bones. (iytmed.com)
  • Osteoporosis may be confused with osteomalacia, but in osteoporosis the bones are porous and brittle, whereas in osteomalacia the bones are soft. (medscape.com)
  • Teriparatide injection is used to treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause ('change in life,' end of menstrual periods), who are at high risk of fractures (broken bones), and cannot use other osteoporosis treatments. (medlineplus.gov)
  • It is also used to increase bone mass in men with certain types of osteoporosis who are at high risk for having broken bones (fractures), and who cannot use other osteoporosis treatments. (medlineplus.gov)
  • Teriparatide injection is also used to treat osteoporosis in men and women who are taking corticosteroids (a type of medication that may cause osteoporosis in some patients) who are at high risk of fractures (broken bones), and cannot use other osteoporosis treatments. (medlineplus.gov)
  • How likely you are to develop osteoporosis depends partly on how much bone mass you attained in your youth. (mayoclinic.org)
  • The higher your peak bone mass, the more bone you have "in the bank" and the less likely you are to develop osteoporosis as you age. (mayoclinic.org)
  • A number of factors can increase the likelihood that you'll develop osteoporosis - including your age, race, lifestyle choices, and medical conditions and treatments. (mayoclinic.org)
  • Women are much more likely to develop osteoporosis than are men. (mayoclinic.org)
  • While often a precursor to osteoporosis, not everyone with osteopenia will develop osteoporosis. (spine-health.com)
  • As a result, women develop osteoporosis far more often than men. (healthwise.net)
  • According to a report published by the International Osteoporosis Foundation (IOF) in 2006, women in Pakistan have a daily calcium intakes of 300 to 500 milligrams range which is less than the ideal intake of 1000 milligrams. (com.pk)
  • The members of the Committee of Scientific Advisors of the International Osteoporosis Foundation ( IOF ) and the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis ( ESCEO ) are developing a very exciting Congress' scientific programme that will bring together the world's best in the field of musculoskeletal health and disease. (wco-iof-esceo.org)
  • Czerwinski E, Badurski JE, Marcinowska-Suchowierska E, Osieleniec J. Current understanding of osteoporosis according to the position of the World Health Organization (WHO) and International Osteoporosis Foundation. (medscape.com)
  • According to recent statistics from the International Osteoporosis Foundation, worldwide, 1 in 3 women over the age of 50 years and 1 in 5 men will experience osteoporotic fractures in their lifetime. (medgadget.com)
  • Actonel is approved to reduce the risk of fractures in postmenopausal women with osteoporosis. (news-medical.net)
  • Denosumab for preventing fractures in postmenopausal women with osteoporosis New is a topic covered in the Cochrane Abstracts . (unboundmedicine.com)
  • Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/439926/all/Denosumab_for_preventing_fractures_in_postmenopausal_women_with_osteoporosis_New. (unboundmedicine.com)
  • Bisphosphonates -- the main drugs used to prevent and treat osteoporosis in postmenopausal women. (medlineplus.gov)
  • 1 Several agents have been used for many years to prevent or treat osteoporosis. (bmj.com)
  • Bisphosphonates are potent inhibitors of resorption and represent 70% of the worldwide market for drugs used to treat osteoporosis. (bmj.com)
  • You can treat osteoporosis through diet and other lifestyle changes. (ucsd.edu)
  • American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. (medscape.com)
  • 1975)‎. Prevention of rickets, osteomalacia and osteoporosis. (who.int)
  • Many osteoporosis treatment tools are similar to prevention methods, such as recommending changes to diet and lifestyle. (hopkinsmedicine.org)
  • The U.S. Food and Drug Administration (FDA) approved a new once-a-month dose (150 mg) of Actonel (risedronate sodium) tablets for the treatment and prevention of postmenopausal osteoporosis. (news-medical.net)
  • Might fruits and vegetables be the unexpected natural answer to the question of osteoporosis prevention? (nutritionfacts.org)
  • Osteoporosis is a lifestyle disease and prevention is the best cure. (osteoporosis.org.za)
  • Clinician's Guide to Prevention and Treatment of Osteoporosis. (medscape.com)
  • 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. (medscape.com)
  • According to the U.S. Department of Health and Human Services Offices of Women's Health (HHS-OWH 2017), of the 10 million people in the US with osteoporosis, 8 million are female. (arizonafoothillsmagazine.com)
  • Fast Five Quiz: Osteoporosis Myths vs Facts - Medscape - Aug 19, 2022. (medscape.com)
  • For people with osteoporosis, bone loss (resorption) outpaces the growth (remodeling) of new bone. (news24.com)
  • A new study suggests that certain yoga poses can lead to bone injuries in people with osteoporosis or osteopenia. (medicalnewstoday.com)
  • In order to verify the link between the practice of yoga and the experience of additional injuries in people with osteoporosis, the research team analyzed the health records of 89 individuals. (medicalnewstoday.com)
  • People with osteoporosis should walk at least 30 minutes daily, use your treadmill while you are watching television, jog, play tennis, do weight training, dance or any exercise that does not present the risk of falling. (safemenopausesolutions.com)
  • Major risk factors of osteoporosis and what should people with osteoporosis do about it! (safemenopausesolutions.com)
  • 4 - People with osteoporosis that have family history or genetic predisposition. (safemenopausesolutions.com)
  • 11 - People with osteoporosis have insufficient calcium absorption and they should supplement their diet with vitamins, minerals, and other nutrients and herbs with the purpose of preventing osteoporosis. (safemenopausesolutions.com)
  • Taking medication, if prescribed, can help prevent fractures in people with osteoporosis. (theinfotree.com)
  • Because excessive free radicals may contribute to bone loss, it's important to elucidate the potential role antioxidant-rich fruits play in mitigating the bone loss that leads to the development of osteoporosis. (nutritionfacts.org)
  • For example, the use of certain drugs has been associated with the development of osteoporosis. (medscape.com)
  • A lifelong lack of calcium plays a major role in the development of osteoporosis. (youchoimd.net)
  • Having too much salt leads to an increasing in the elimination of calcium, which helps the development of osteoporosis. (botanical-online.com)
  • Osteoporosis affects men and women of all races. (mayoclinic.org)
  • Osteoporosis affects more than 10 million Americans. (hopkinsmedicine.org)
  • Osteoporosis affects millions of older adults. (healthwise.net)
  • Video presents an overview of understanding how osteoporosis affects individuals with a spinal cord injury (SCI). (naric.com)
  • 9 - Cigarette smoking affects hormone imbalance and osteoporosis. (safemenopausesolutions.com)
  • Although it is a preventable disease, osteoporosis affects an estimated 25 million people worldwide, leading to 1 million fractures, 40 000 annual deaths and health costs of billions of dollars [4-6]. (who.int)
  • Osteoporosis mainly affects women. (comportho.com)
  • Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. (mayoclinic.org)
  • Any bone can break due to osteoporosis, but some of the most serious and common fractures are those of the spine and hip. (news24.com)
  • Hip fractures may occur less in our black population, but osteoporosis in the spine and subsequent spine fractures seems to occur equally in all race groups. (news24.com)
  • A new NCHS Health E-Stat provides information on the percentage of U.S. adults aged 65 and over with osteoporosis and low bone mass at the femur neck or lumbar spine, using data from the 2005-2010 National Health and Nutrition Examination Survey. (cdc.gov)
  • Key exercises for osteoporosis target the spine and hips, where fractures are most likely to occur. (qualityhealth.com)
  • If you have osteoporosis, don't allow a therapist to deep massage near your spine. (dummies.com)
  • Bone fractures, particularly in the spine or hip, are the most serious complication of osteoporosis. (youchoimd.net)
  • Hip, wrist, or spine fractures are usually associated with osteoporosis. (theinfotree.com)
  • Osteoporosis is a systemic disease that causes the skeleton to become porous and brittle and this can lead to fractures of the forearm, spine and hip. (osteoporosis.org.za)
  • Osteoporosis is a chronic, debilitating disease that is most distressing to patients and health care providers in the occurrence of fractures of the hip and spine. (healthplexus.net)
  • Osteoporosis is defined as a bone mineral density of 2.5 standard deviations or more below the mean value for a young woman at either the femur neck or the lumbar spine, or both locations, as measured by dual energy x-ray absorptiometry. (cdc.gov)
  • Radiographs of the pelvis and lumbosacral spine reveal pseudofractures and other evidence of severe osteomalacia and mild osteoporosis. (cdc.gov)
  • Topics include: what osteoporosis is, bony anatomy, osteoporosis and SCI, fractures and SCI, causes of osteoporosis in SCI, treatment of fractures in SCI, medications and exercises for osteoporosis, and recommendations. (naric.com)
  • Despite the wide prevalence of osteoporosis, no proper cure has been found yet. (com.pk)
  • Furthermore, new studies have shown the prevalence of osteoporosis in men is higher than previously thought with approximately one in five men affected. (osteoporosis.org.za)
  • Growing prevalence of bone related diseases such as osteoporosis is driving growth of the external fixators market. (medgadget.com)
  • North America is expected to gain significant growth over the forecast period owing to the high prevalence of osteoporosis in the region. (medgadget.com)
  • The USPSTF makes no recommendation for or against routine osteoporosis screening in postmenopausal women who are younger than 60 or in women aged 60-64 who are not at increased risk for osteoporotic fractures. (uspreventiveservicestaskforce.org)
  • Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue. (livescience.com)
  • Osteoporosis means porous bone. (cooperhealth.org)
  • Early treatment of osteoporosis and osteopenia can ease pain, limit or halt bone loss, and prevent fractures. (hopkinsmedicine.org)
  • Updated ) Osteoporosis drugs including oral bisphosphonates show efficacy and safety in the treatment of bone loss in patients with chronic kidney disease (CKD) in several observational studies. (medscape.com)
  • Most cases were reported in cancer patients receiving intravenous bisphosphonates, but some have been in patients treated orally for osteoporosis. (news-medical.net)
  • The most commonly prescribed medications for osteoporosis are antiresorptive drugs, known as bisphosphonates. (ucsd.edu)
  • Osteoporosis occurs when the creation of new bone doesn't keep up with the loss of old bone. (mayoclinic.org)
  • You may need blood and urine tests if your provider thinks the cause of your osteoporosis is a medical condition, rather than the slow bone loss that occurs with aging. (medlineplus.gov)
  • When those components are lost too rapidly or not replenished quickly enough (or both), osteoporosis occurs. (hopkinsmedicine.org)
  • The bone loss that occurs as part of osteoporosis is progressive (it continues over time), and there often are no symptoms until a bone breaks. (cooperhealth.org)
  • Osteoporosis occurs when extra bone mass is lost and bone tissue changes. (theinfotree.com)
  • Effects of Kisspeptin on Bone Metabolism in Healthy Men The beneficial effects of kisspeptin on bone metabolism could lead to a potentially exciting new role for this hormone in the treatment of osteoporosis. (medscape.com)
  • BMD tests can identify osteoporosis, determine your risk for fractures, and measure your response to osteoporosis treatment. (livescience.com)
  • A comprehensive osteoporosis treatment program includes a focus on proper nutrition, exercise , and safety issues to prevent falls that may result in fractures. (livescience.com)
  • Treatment for osteoporosis includes medicine to reduce bone loss and to build bone strength. (healthwise.net)
  • The standard of care for treating osteoporosis has changed since 2008, when treatment recommendations were based solely on a person's bone mineral density. (ucsd.edu)
  • A modestly increased risk for atrial fibrillation was seen during the first year of treatment with zoledronic acid (Reclast) for osteoporosis, and a nonsignificant trend toward an increased risk when the drug was used for malignancy-related bone disease, a researcher reported. (medpagetoday.com)
  • It's especially important for osteoporosis treatment to add green leafy vegetables to your diet. (safemenopausesolutions.com)
  • Women are much more likely to be screened and treated for osteoporosis than men of the same age, researchers at the University of Washington found, concluding that, "Current guidelines are inadequate for identifying men who would benefit from osteoporosis evaluation and preventive treatment. (thedoctorwillseeyounow.com)
  • The study compared rates of osteoporosis testing and treatment in men and women 70 years old or older receiving care at a Veterans Affairs (VA) medical center. (thedoctorwillseeyounow.com)
  • But if this does pan out for other plants, a "fruit and vegetables" approach may provide a very sensible (and natural) alternative therapy for osteoporosis treatment, one that is likely to have numerous additional health-related benefits. (nutritionfacts.org)
  • Finding a healthcare provider that specializes in osteoporosis can make a big difference when seeking a diagnosis and treatment options. (verywellhealth.com)
  • Treatment for osteoporosis is related to drug discovery alternative to hormone therapy estrogen offset the disadvantages of this therapy. (bvsalud.org)
  • The aims of this review were report the effect of the osteoporosis on the alveolar bone and demonstrate the efficacy of the therapies currently used for treatment of this disease, emphasizing studies on the Selective Estrogen Receptor Modulators and the sodium fluoride. (bvsalud.org)
  • The review was divided into 3 topics: (1) Bone metabolism, (2) Effects of the osteoporosis on the alveola bone, (3) Therapies used for treatment of the osteoporosis. (bvsalud.org)
  • Various nonpharmacological modalities may be used adjunctively with prescribed agents to improve the quality of life of patients with fractures due to osteoporosis. (healthplexus.net)
  • The fall in estrogen levels in women at menopause is one of the strongest risk factors for developing osteoporosis. (mayoclinic.org)
  • This means that at age 80, almost one third of women with normal age-related bone loss would have osteoporosis, based on their DEXA scan results. (medlineplus.gov)
  • Yes, men do get osteoporosis, but women are at greater risk. (livescience.com)
  • Up to 1 in 2 women will break a bone due to osteoporosis - equal to the risk of breast, ovarian and uterine cancer combined. (hopkinsmedicine.org)
  • So the older women get, the more likely they are to have osteoporosis. (healthwise.net)
  • Osteoporosis is much more common in women than in men. (healthwise.net)
  • The leading cause of osteoporosis is a lack of certain hormones, particularly estrogen in women and androgen in men. (com.pk)
  • Women, especially those older than 60 years of age, are frequently diagnosed with osteoporosis. (com.pk)
  • Osteoporosis is often considered to be a condition limited to frail elderly women. (com.pk)
  • Osteoporosis and low bone mass (a condition called osteopenia) are a major public health problem for an estimated 44 million U.S. women and men aged 50 and older. (cooperhealth.org)
  • Of the approximately 10 million Americans who currently have osteoporosis, 80% are women. (cooperhealth.org)
  • As a result, about one in two women over age 50 will break a bone due to osteoporosis. (cooperhealth.org)
  • The main cause of osteoporosis is a low level of hormones, particularly estrogen in women and testosterone in men. (cooperhealth.org)
  • Postmenopausal women are frequently diagnosed with osteoporosis because menopause is accompanied by a sharp drop in estrogen levels. (cooperhealth.org)
  • Eighty percent of those affected by osteoporosis are women, but younger women and men can also be at risk. (coxhealth.com)
  • The U.S. Preventive Services Task Force (USPSTF) recommends that women aged 65 and older be screened routinely for osteoporosis. (uspreventiveservicestaskforce.org)
  • Preventing osteoporosis is crucial for men and women! (safemenopausesolutions.com)
  • Men and women that are very thin, chronically underweight and have eating disorders are at risk for osteoporosis. (safemenopausesolutions.com)
  • 3 - Caucasian and Asian women are more likely to get osteoporosis and lower bone density. (safemenopausesolutions.com)
  • 8 - Women that experience a hysterectomy and have their ovaries removed could experience osteoporosis as a side effect of hysterectomy. (safemenopausesolutions.com)
  • It's not clear why men in the U.S. do not get tested and screened for osteoporosis as they age the way women do. (thedoctorwillseeyounow.com)
  • An estimated 1 in 2 women and 1 in 8 men over the age of 50 years will have osteoporosis-related fractures in their lifetime [3,6]. (who.int)
  • One in 2 U.S. women and 1 in 4 U.S. men older than 50 will have a broken bone at some point in their life because of osteoporosis. (comportho.com)
  • In South Africa, 1 in 3 women and 1 in 5 men will possibly develop this disease within their lifetime - which means potentially between 4 and 6 million South Africans suffer from Osteoporosis. (osteoporosis.org.za)
  • Osteoporosis causes more than 8.9 million fractures globally each year, and research estimates that around 40% of women and 30% of men will experience osteoporosis-related fractures. (verywellhealth.com)
  • Osteoporosis is far more typical in women than in men, especially after menopause. (iytmed.com)
  • Routine screening for osteoporosis in men is not as widespread a practice as is screening in women. (medscape.com)
  • Osteoarthritis, osteoporosis, or other. (cdc.gov)
  • Certain medications (prednisone, e.g.) and diseases can also cause bone loss and increase the risk of osteoporosis. (hopkinsmedicine.org)
  • some risks may cause or increase the risk of osteoporosis. (theinfotree.com)
  • Cooper University Health Care has a skilled team of board-certified specialists with extensive expertise in diagnosing and treating osteoporosis. (cooperhealth.org)
  • In addition to taking the appropriate foods for osteoporosis, the following recommendations should be followed to improve the assimilation of the nutrients in the diet and the health of the organism. (botanical-online.com)
  • Men and women's bodies need nutritious food and a quality vitamin/mineral supplement to improve and maintain our health and preventing osteoporosis. (safemenopausesolutions.com)
  • Fluoride can affect osteoporosis and your health. (safemenopausesolutions.com)
  • It is our hope that National Osteoporosis Month motivates everyone to take simple steps toward improving their bone health and living active, independent lives. (womenfitness.net)
  • We urgently need public health strategies to maintain bone health, and prevent osteoporosis. (nutritionfacts.org)
  • Osteoporosis can lead to fractures, pain, and mental health problems. (verywellhealth.com)
  • Finding the right healthcare provider, working with a mental health professional, and participating in an osteoporosis support group can help. (verywellhealth.com)
  • The Bone Health and Osteoporosis Foundation also offers online medical professional search tools. (verywellhealth.com)
  • Although osteoporosis is a preventable disease affecting millions of people, public awareness remains low. (who.int)
  • Other factors that can contribute to developing osteoporosis are a lack of dietary calcium and vitamin D, a sedentary lifestyle, thyroid and other medical conditions, smoking and chronic alcohol use. (cooperhealth.org)
  • Solutions for preventing osteoporosis are exercise, calcium supplements and natural progesterone supplementation. (safemenopausesolutions.com)
  • If you are experiencing osteoporosis, you could benefit a great deal by taking a quality multiple vitamin/mineral and a calcium supplement. (safemenopausesolutions.com)
  • Calcium deficiency also effects the heart and circulatory system, as well as the secretion of essential hormones and preventing osteoporosis. (safemenopausesolutions.com)
  • 12 - Hypothyroidism, excessive thyroid medication, antibiotics, certain cancer treatments, treatments for endometriosis and corticosteroid medication can all impair calcium absorption and be major risk factors of osteoporosis. (safemenopausesolutions.com)
  • In spite of all the calcium that dairy includes, some believe that its high protein content can cause osteoporosis. (iytmed.com)
  • Osteoporosis increases the risk of breaking a bone. (medlineplus.gov)
  • Menopause is accompanied by lower estrogen levels and increases a woman's risk of osteoporosis. (com.pk)
  • Having osteopenia increases your risk of developing osteoporosis. (cooperhealth.org)
  • Regular consumption of more than two alcoholic drinks a day increases your risk of osteoporosis. (youchoimd.net)
  • 4 , 5 Low weight and no current use of estrogen therapy are incorporated with age into the 3-item Osteoporosis Risk Assessment Instrument (ORAI). (uspreventiveservicestaskforce.org)
  • You might want to talk to your doctor about osteoporosis if you went through early menopause or took corticosteroids for several months at a time, or if either of your parents had hip fractures. (mayoclinic.org)
  • 2 - Osteoporosis usually accelerates during menopause, but it could begin 30 years prior to menopause. (safemenopausesolutions.com)
  • You are more likely to have osteoporosis if you didn't reach your ideal bone density during your childhood and teen years. (healthwise.net)
  • Since a diagnosis of osteopenia puts one at greater risk for osteoporosis, patients are encouraged to seek the advice of their physicians about implementing preventive measures. (spine-health.com)
  • People who have an extremely low BMI are at greater risk for osteoporosis than people of normal or high BMI. (comportho.com)
  • Bone density tests can also identify patients with osteopenia - decreased bone mass that has not yet reached the level of osteoporosis. (hopkinsmedicine.org)
  • The new study's findings - featured in the journal Mayo Clinic Proceedings - indicate that certain yoga poses may harm people with osteopenia or osteoporosis, leading to further soft tissue and bone injury. (medicalnewstoday.com)
  • The researchers do not discourage people with osteopenia or osteoporosis from practicing yoga. (medicalnewstoday.com)
  • But if you have osteoporosis or osteopenia, you should modify the postures to accommodate your condition. (medicalnewstoday.com)
  • Osteopenia is a condition where bone mineral density is lower than normal, but not low enough to be classified as osteoporosis. (spine-health.com)
  • Natural progesterone can help you re-balance your hormones, reverse osteoporosis and safely reduce or eliminate hormone imbalance symptoms. (safemenopausesolutions.com)
  • Natural progesterone is an effective alternative to give your body the hormone balance you need and to reduce or eliminate risk factors of osteoporosis. (safemenopausesolutions.com)
  • In osteoporosis, the mineral-to-collagen ratio is within the reference range, whereas in osteomalacia, the proportion of mineral composition is reduced relative to organic matrix content. (medscape.com)
  • Up to 1 in 4 men will break a bone due to osteoporosis - a risk greater than prostate cancer. (hopkinsmedicine.org)
  • 1,2 As the world's population ages, osteoporosis and the subsequent fractures will become increasingly common. (lww.com)
  • Patients with PD are at greater risk of falls and fractures, and risk of injury is compounded by the high rates of osteoporosis [ 4 - 6 ]. (hindawi.com)
  • Here at Arthritis, Rheumatic & Bone Disease Associates, we treat a number of patients who suffer from osteoporosis or other conditions that feature a lack of bone. (arthritissj.com)
  • In commenting on the research, Michael Econs, MD, a professor in the Indiana University School of Medicine, in Indianapolis, and incoming ASBMR president, said this work offers important insight to add to knowledge of osteoporosis drugs in CKD. (medscape.com)
  • Schools can be one of the best venues for increasing knowledge of osteoporosis and inducing lasting behavioural change during adolescence, the period of peak bone density [9,11-13]. (who.int)
  • In the United States, more than 53 million people either already have osteoporosis or are at high risk due to low bone mass. (trellushealth.net)
  • Cooper performs over 2,000 DEXA scans a year-more than any other facility in the region, reflecting the depth of our experience in diagnosing osteoporosis. (cooperhealth.org)