Osteoporosis
Osteoporosis, Postmenopausal
Bone Density
The amount of mineral per square centimeter of BONE. This is the definition used in clinical practice. Actual bone density would be expressed in grams per milliliter. It is most frequently measured by X-RAY ABSORPTIOMETRY or TOMOGRAPHY, X RAY COMPUTED. Bone density is an important predictor for OSTEOPOROSIS.
Bone Density Conservation Agents
Osteoporotic Fractures
Diphosphonates
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
Absorptiometry, Photon
A noninvasive method for assessing BODY COMPOSITION. It is based on the differential absorption of X-RAYS (or GAMMA RAYS) by different tissues such as bone, fat and other soft tissues. The source of (X-ray or gamma-ray) photon beam is generated either from radioisotopes such as GADOLINIUM 153, IODINE 125, or Americanium 241 which emit GAMMA RAYS in the appropriate range; or from an X-ray tube which produces X-RAYS in the desired range. It is primarily used for quantitating BONE MINERAL CONTENT, especially for the diagnosis of OSTEOPOROSIS, and also in measuring BONE MINERALIZATION.
Fractures, Spontaneous
Alendronate
Bone and Bones
Teriparatide
A polypeptide that consists of the 1-34 amino-acid fragment of human PARATHYROID HORMONE, the biologically active N-terminal region. The acetate form is given by intravenous infusion in the differential diagnosis of HYPOPARATHYROIDISM and PSEUDOHYPOPARATHYROIDISM. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
Etidronic Acid
Bone Remodeling
The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.
Lumbar Vertebrae
Hip Fractures
Raloxifene
Osteoclasts
Calcaneus
Calcium, Dietary
Osteoblasts
Vitamin D
A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.
Selective Estrogen Receptor Modulators
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
Glucocorticoids
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Calcitonin
Risk Factors
Osteocalcin
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
Hip
RANK Ligand
Estrogen Replacement Therapy
The use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, DYSPAREUNIA, and progressive development of OSTEOPOROSIS. This may also include the use of progestational agents in combination therapy.
Parathyroid Hormone
A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
Osteoprotegerin
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
Densitometry
Alkaline Phosphatase
Postmenopause
Radius
Collagen Type I
Osteomalacia
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Estrogens
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
Menopause
Bone Development
Tibia
Femoral Neck Fractures
Minerals
Native, inorganic or fossilized organic substances having a definite chemical composition and formed by inorganic reactions. They may occur as individual crystals or may be disseminated in some other mineral or rock. (Grant & Hackh's Chemical Dictionary, 5th ed; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Fractures, Compression
Mass Screening
Cathepsin K
Biological Markers
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
Prevalence
Thoracic Vertebrae
Age Factors
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Calcification, Physiologic
Hormone Replacement Therapy
Anabolic Agents
Back Pain
Endocrine System Diseases
Microradiography
Production of a radiographic image of a small or very thin object on fine-grained photographic film under conditions which permit subsequent microscopic examination or enlargement of the radiograph at linear magnifications of up to several hundred and with a resolution approaching the resolving power of the photographic emulsion (about 1000 lines per millimeter).
Hip Joint
Vitamin D Deficiency
A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406)
Cross-Sectional Studies
Low Density Lipoprotein Receptor-Related Protein-5
Aging
Bone Demineralization, Pathologic
Decrease, loss, or removal of the mineral constituents of bones. Temporary loss of bone mineral content is especially associated with space flight, weightlessness, and extended immobilization. OSTEOPOROSIS is permanent, includes reduction of total bone mass, and is associated with increased rate of fractures. CALCIFICATION, PHYSIOLOGIC is the process of bone remineralizing. (From Dorland, 27th ed; Stedman, 25th ed; Nicogossian, Space Physiology and Medicine, 2d ed, pp327-33)
Risk Assessment
Osteocytes
Dietary Supplements
Products in capsule, tablet or liquid form that provide dietary ingredients, and that are intended to be taken by mouth to increase the intake of nutrients. Dietary supplements can include macronutrients, such as proteins, carbohydrates, and fats; and/or MICRONUTRIENTS, such as VITAMINS; MINERALS; and PHYTOCHEMICALS.
Treatment Outcome
Kyphosis
Hypogonadism
Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
Receptor Activator of Nuclear Factor-kappa B
A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Minority Health
Cholecalciferol
Hydroxycholecalciferols
Dietary intake and practices in the Hong Kong Chinese population. (1/3580)
OBJECTIVES: To examine dietary intake and practices of the adult Hong Kong Chinese population to provide a basis for future public health recommendations with regard to prevention of certain chronic diseases such as cardiovascular disease, hypertension, and osteoporosis. PARTICIPANTS: Age and sex stratified random sample of the Hong Kong Chinese population aged 25 to 74 years (500 men, 510 women). METHOD: A food frequency method over a one week period was used for nutrient quantification, and a separate questionnaire was used for assessment of dietary habits. Information was obtained by interview. RESULTS: Men had higher intakes of energy and higher nutrient density of vitamin D, monounsaturated fatty acids and cholesterol, but lower nutrient density of protein, many vitamins, calcium, iron, copper, and polyunsaturated fatty acids. There was an age related decrease in energy intake and other nutrients except for vitamin C, sodium, potassium, and percentage of total calorie from carbohydrate, which all increased with age. Approximately 50% of the population had a cholesterol intake of < or = 300 mg; 60% had a fat intake < or = 30% of total energy; and 85% had a percentage of energy from saturated fats < or = 10%; criteria considered desirable for cardiovascular health. Seventy eight per cent of the population had sodium intake values in the range shown to be associated with the age related rise in blood pressure with age. Mean calcium intake was lower than the FAO/WHO recommendations. The awareness of the value of wholemeal bread and polyunsaturated fat spreads was lower in this population compared with that in Australia. There was a marked difference in types of cooking oil compared with Singaporeans, the latter using more coconut/palm/mixed vegetable oils. CONCLUSION: Although the current intake pattern for cardiovascular health for fat, saturated fatty acid, and cholesterol fall within the recommended range for over 50% of the population, follow up surveys to monitor the pattern would be needed. Decreasing salt consumption, increasing calcium intake, and increasing the awareness of the health value of fibre may all be beneficial in the context of chronic disease prevention. (+info)Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study. (2/3580)
OBJECTIVE: To study the effect of cyclic etidronate in secondary prevention of corticosteroid induced osteoporosis. METHODS: A double blind, randomised placebo controlled study comparing cyclic etidronate and placebo during two years in 37 postmenopausal women receiving long term corticosteroid treatment, mainly for polymyalgia rheumatica (40% of the patients) and rheumatoid arthritis (30%). Bone density was measured in the lumbar spine, femoral neck, and femoral trochanter. RESULTS: After two years of treatment there was a significant difference between the groups in mean per cent change from baseline in bone density in the spine in favour of etidronate (p = 0.003). The estimated treatment difference (mean (SD)) was 9.3 (2.1)%. Etidronate increased bone density in the spine (4.9 (2.1)%, p < 0.05) whereas the placebo group lost bone (-2.4 (1.6)%). At the femoral neck there was an estimated difference of 5.3 (2.6)% between the groups (etidronate: 3.6% (1.4)%, p < 0.05, placebo: -2.4 (2.1)%). The estimated difference at the trochanter was 8.2 (3.0) (etidronate: 9.0 (1.5)%, p < 0.0001, placebo: 0.5 (2.3)%). No significant bone loss occurred in the hip in placebo treated patients. CONCLUSIONS: Cyclic etidronate is an effective treatment for postmenopausal women receiving corticosteroid treatment and is well tolerated. (+info)Dietary isoflavones: biological effects and relevance to human health. (3/3580)
Substantial evidence indicates that diets high in plant-based foods may explain the epidemiologic variance of many hormone-dependent diseases that are a major cause of mortality and morbidity in Western populations. There is now an increased awareness that plants contain many phytoprotectants. Lignans and isoflavones represent two of the main classes of phytoestrogens of current interest in clinical nutrition. Although ubiquitous in their occurrence in the plant kingdom, these bioactive nonnutrients are found in particularly high concentrations in flaxseeds and soybeans and have been found to have a wide range of hormonal and nonhormonal activities that serve to provide plausible mechanisms for the potential health benefits of diets rich in phytoestrogens. Data from animal and in vitro studies provide convincing evidence for the potential of phytoestrogens in influencing hormone-dependent states; although the clinical application of diets rich in these estrogen mimics is in its infancy, data from preliminary studies suggest beneficial effects of importance to health. This review focuses on the more recent studies pertinent to this field and includes, where appropriate, the landmark and historical literature that has led to the exponential increase in interest in phytoestrogens from a clinical nutrition perspective. (+info)Walker 256/S carcinosarcoma causes osteoporosis-like changes through ectopical secretion of luteinizing hormone-releasing hormone. (4/3580)
We have shown that Walker 256/S mammary carcinoma caused osteoporosis-like changes in young female rats, accompanied by low serum estradiol and hypercalciuria without changes in the serum levels of calcium, phosphorus, and parathyroid hormone-related peptide. In this study, we investigated the cause of bone loss after Walker 256/S inoculation into female 6-week-old Wistar Imamichi rats, focusing on the sex hormone balance in the host animal. Walker 256/S-bearing rats showed characteristic osteoporosis, with a significant increase in spleen weight and a significant decrease in uterine weight by 14 days after s.c. tumor inoculation. In the in vitro bone marrow culture, mineralized nodule formation ability decreased according to the time after tumor inoculation, and tartrate-resistant acid phosphatase-positive multinucleated cell formation increased at 7 days after tumor inoculation, but it began to decrease at 14 days after tumor inoculation. This indicates that after inoculation with Walker 256/S tumor, the progenitors of osteoblasts and ostroclasts lost their balance in the bone turnover, resulting in bone resorption. On the other hand, Walker 256/S carcinoma expressed luteinizing hormone-releasing hormone (LH-RH) mRNA, and in Walker 256/S-bearing rats, the serum LH-RH level increased significantly from 3 days after tumor inoculation, whereas in the healthy control rats, this level was very low. Consequently, the serum levels of follicle-stimulating hormone, luteinizing hormone, estradiol, and progesterone were significantly lower in the tumor-bearing rats than in the healthy control rats. Because the LH-RH gene is located in the long prolactin release-inhibiting factor (PIF) gene and mRNA amplified by reverse transcription-PCR in this study contained whole LH-RH and a part of PIF, the Walker 256/S tumor is thought to express PIF. Indeed, the serum prolactin level decreased in tumor-bearing rats. The serum level of growth hormone, one of the other pituitary hormones, was not changed. Moreover, the level of an osteolytic cytokine, tumor necrosis factor alpha, increased in the serum of Walker 256/S-bearing rats, although this may be a result of the immune response of the host animal to tumor growth as well as an enlarged spleen. In conclusion, the Walker 256/S tumor lowers estrogen secretion through ectopical oversecretion of LH-RH, and then osteolytic cytokines, such as tumor necrosis factor alpha, increase in tumor-bearing rats, escape the control of estrogen, and activate osteoclasts, resulting in bone loss in a short period. (+info)A high incidence of vertebral fracture in women with breast cancer. (5/3580)
Because treatment for breast cancer may adversely affect skeletal metabolism, we investigated vertebral fracture risk in women with non-metastatic breast cancer. The prevalence of vertebral fracture was similar in women at the time of first diagnosis to that in an age-matched sample of the general population. The incidence of vertebral fracture, however, was nearly five times greater than normal in women from the time of first diagnosis [odds ratio (OR), 4.7; 95% confidence interval (95% CI), 2.3-9.9], and 20-fold higher in women with soft-tissue metastases without evidence of skeletal metastases (OR, 22.7; 95% CI, 9.1-57.1). We conclude that vertebral fracture risk is markedly increased in women with breast cancer. (+info)Bone densitometry at a district general hospital: evaluation of service by doctors and patients. (6/3580)
OBJECTIVE: To assess doctors' and patients' views about a district general hospital bone densitometry service and to examine existing practice to influence future provision. DESIGN: Three postal surveys: (a) of doctors potentially using the service, (b) of patients undergoing a bone densitometry test during a six month period, and (c) of the referring doctors of the patients undergoing the test. SETTING: Bone densitometry service at South Cleveland Hospital, Middlesbrough and two district health authorities: South Tees and Northallerton. SUBJECTS: All general practitioners (n=201) and hospital consultants in general medicine, rheumatology, obstetrics and gynaecology, orthopaedics, radio therapy and oncology, haematology, and radiology (n=61); all patients undergoing an initial bone densitometry test (n=309) during a six month period; and their referring doctors. MAIN MEASURES: Service awareness and use, knowledge of clinical indications, test results, influence of test results on patient management, satisfaction with the service and its future provision. RESULTS: The overall response rates for the three surveys were 87%, 70%, and 61%. There was a high awareness of the service among doctors and patients; 219(84%) doctors were aware and 155 of them (71%) had used it, and patients often (40%) suggested the test to their doctor. The test was used for a range of reasons including screening although the general use was consistent with current guidelines. Two hundred (65%) bone densitometry measurements were normal, 71(23%) were low normal, and 38(12%) were low. Although doctors reported that management of patients had been influenced by the test results, the algorithm for decision making was unclear. Patients and doctors were satisfied with the service and most (n=146, 68%) doctors wanted referral guidelines for the service. CONCLUSIONS: There was a high awareness of, use of, and satisfaction with the service. Patients were being referred for a range of reasons and a few of these could not be justified, many tests were normal, and clinical decision making was not always influenced by the test result. It is concluded that bone densitometry services should be provided but only for patients whose management will be influenced by test results and subject to guidelines to ensure appropriate use of the technology. (+info)Osteoporosis: review of guidelines and consensus statements. (7/3580)
This activity is designed for physicians, pharmacists, nurses, health planners, directors of managed care organizations, and payers of health services. GOAL: To understand current guidelines and consensus statements regarding the prevention, diagnosis, and treatment of osteoporosis. OBJECTIVE: List four national or international organizations involved in the development of consensus statements regarding the prevention, diagnosis, and treatment of osteoporosis. 2. Discuss the significant differences among different countries regarding the prevention and treatment of osteoporosis. 3. List the major risk factors for osteoporosis. 4. Describe the differences in the application of bone mineral density scans, biochemical markers, and ultrasound in evaluating patients with suspected osteopenia and osteoporosis. 5. Distinguish between and briefly discuss therapeutic modalities used in primary prevention, secondary prevention, and treatment of osteoporosis. 6. Discuss the advantages and disadvantages of estrogen/hormone replacement therapy. 7. Describe alternatives to estrogen/hormone replacement therapy. (+info)Development and validation of a simple questionnaire to facilitate identification of women likely to have low bone density. (8/3580)
The relationship between low bone mass and risk of fracture is well documented. Although bone densitometry is the method of choice for detecting low bone mass, its use may be limited by the availability of equipment, cost, and reimbursement issues. Improved patient selection for bone densitometry might increase the cost-effectiveness of screening for osteoporosis, a goal we sought to achieve by developing and validating a questionnaire based solely on patient-derived data. Responses to the questionnaire were used to assign postmenopausal women to one of two groups: (1) those unlikely to have low bone mineral density (defined as 2 standard deviations or more below the mean bone mass at the femoral neck in young, healthy white women) and therefore probably not currently candidates for bone densitometry; and (2) those likely to have low bone mineral density and therefore probably candidates for bone densitometry. We asked community-dwelling perimenopausal and postmenopausal women attending one of 106 participating multispecialty centers (both academic and community based) to complete a self-administered questionnaire and undergo bone density measurement using dual x-ray absorptiometry. We used regression modeling to identify factors most predictive of low bone density at the femoral neck in the postmenopausal group. A simple additive scoring system was developed based on the regression model. Results were validated in a separate cohort of postmenopausal women. Data were collected from 1279 postmenopausal women in the development cohort. Using only six questions (age, weight, race, fracture history, rheumatoid arthritis history, and estrogen use), we achieved a target of 89% sensitivity and 50% specificity. The likelihood ratio was 1.78. Validation in a separate group of 207 postmenopausal women yielded 91% sensitivity and 40% specificity. Assuming population characteristics similar to those of our development cohort, use of our questionnaire could decrease the use of bone densitometry by approximately 30%. Sensitivity and specificity can be varied by changing the level for referral for densitometry to provide the most cost-effective use within a particular healthcare setting. Thus use of our questionnaire, an inexpensive prescreening tool, in conjunction with physician assessment can optimize the use of bone densitometry and may lead to substantial savings in many healthcare settings where large numbers of women require evaluation for low bone mass. (+info)
Comparison of the male osteoporosis risk estimation score (MORES) with frax in identifying men at risk for osteoporosis<...
Management of glucocorticoid-induced osteoporosis: prevalence, and eme | DHPS
Secondary osteoporosis - NatureWord
Osteoporosis risk factors in Indonesian women - Menopause
Report of the Senate Ad Hoc Committee on Osteoporosis :: Arizona State Government Publications
Osteoporosis International - Research - The Capital Region of Denmark
Osteoporosis Prevention Resources Bend OR - osteopenia, Bend OR osteoporosis, Bend OR thinning of the bone, Bend OR ...
Osteoporosis resident survival guide - wikidoc
Glucocorticoid-Induced Osteoporosis - The Rheumatologist
A neglected requirement for optimizing treatment of age-related osteoporosis: Replenishing the skeletons base reservoir with...
A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis. - Nuffield Department...
FDA Approves New Injectable Osteoporosis Treatment for Postmenopausal Women - Healthcanal.com : Healthcanal.com
Simple calculated osteoporosis risk estimation financial definition of simple calculated osteoporosis risk estimation
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Treatment of male osteoporosis
Osteoporosis Treatment Buckhannon WV - brittle bones, Buckhannon WV minerals bones, Buckhannon WV osteoporosis, Buckhannon WV...
Osteoporosis Treatment Chaska MN - brittle bones, Chaska MN minerals bones, Chaska MN osteoporosis, Chaska MN orthopedics,...
Denosumab in Current Users of Bisphosphonates for Glucocorticoid-induced Osteoporosis - Full Text View - ClinicalTrials.gov
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Treatment To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis: Update of a 2007 Report | Effective...
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Genistein aglycone reverses glucocorticoid-induced osteoporosis and increases bone breaking strength in rats: a comparative...
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Barriers to effective management of osteoporosis in moderate and minimal trauma fractures: a prospective study | Garvan...
femur & vertebrae osteoporosis model Manufacturer, Supplier In Delhi, India
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mental health | Baby Boom Icon Sally Field Takes On Osteoporosis
Pharmacology of bicalutamide
Marcus R, Feldman D, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... osteoporosis, pathological fractures, decrease of muscle mass and tone, progressive anaemia, asthenia, and depression) (Tyrrell ... in rat models of osteoporosis". Biol. Pharm. Bull. 26 (11): 1563-9. doi:10.1248/bpb.26.1563. PMID 14600402. Nagata N, Miyakawa ...
Jillian Cornish
"Our People , Osteoporosis". osteoporosis.org.nz. Retrieved 27 March 2019. "ANZBMS - Office Bearers and Council". www.anzbms.org ... "Our People". Osteoporosis. Retrieved 2 March 2018. "Staff". Cmdt.org.nz. Retrieved 2 March 2018. "Documents The Lens - Free & ... Osteoporosis New Zealand Australia and New Zealand Bone and Mineral Society International Society of Bone Morphometry ...
Bone disease
"Osteoporosis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. El-Najjar M and Robertson Jr AL. 1976. Spongy ... Osteogenesis imperfecta Osteomalacia Osteomyelitis Osteopenia Osteopetrosis Osteoporosis Porotic hyperostosis Primary ...
Snyder-Robinson syndrome
... osteoporosis; marfanoid habitus; and scoliosis, kyphosis, or both (kyphoscoliosis). Distinctive facial features include a cleft ...
Pharmacodynamics of estradiol
ISBN 978-1-84214-263-9. Robert Marcus; David W. Dempster; Jane A. Cauley; David Feldman (13 June 2013). Osteoporosis. Academic ...
Iliocostal friction syndrome
... most commonly occurs bilaterally as a result of spinal osteoporosis. Osteoporosis is a condition ... The most common fractures that occur due to osteoporosis is in the hip or vertebrae, resulting in a loss of space between the ... It is estimated that osteoporosis can cause 25% of females over 50 years of age within the United States to have at least one ... It may occur unilaterally due to conditions such as scoliosis, or bilaterally due to conditions such as osteoporosis and ...
Side effects of bicalutamide
The risk of osteoporosis and serious bone fractures with bicalutamide monotherapy appears to be no different than with non-use ... However, due to the loss of estrogen, bone loss will accelerate and the risk of osteoporosis developing with long-term therapy ... Feldman D, Marcus R, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... osteoporosis, and frailty). According to Iversen et al. (2006), the increased non-prostate cancer mortality with bicalutamide ...
Peak bone mass
"Osteoporosis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. August 2014. Retrieved 16 May 2015. ... Bonjour, J. -Ph; Theintz, G; Law, F; Slosman, D; Rizzoli, R (1994). "Peak bone mass". Osteoporosis International. 4: 7-13. doi: ... this time males typically undergo a longer bone maturation period than women which is why women are more prone to osteoporosis ...
Relative energy deficiency in sport
Osteoporosis is defined by the National Institutes of Health as ''a skeletal disorder characterized by compromised bone ... Osteoporosis. 2006. National Institutes of Health. Retrieved on 2007-10-24. Ott, Susan. 2007. Estrogen: Mechanism of Bone ... Patients with RED-S get osteoporosis due to hypoestrogenemia, or low estrogen levels. With estrogen deficiency, the osteoclasts ... Low energy availability with or without eating disorders, functional hypothalamic amenorrhea, and osteoporosis, alone or in ...
Bicalutamide
Marcus R, Feldman D, Nelson D, Rosen CJ (8 November 2007). Osteoporosis. Academic Press. pp. 1354-. ISBN 978-0-08-055347-4. ... bicalutamide monotherapy is not associated with decreased bone mineral density or osteoporosis. Conversely, bicalutamide ...
Osteonecrosis of the jaw
However, osteoporosis is essentially the result of a lack of new bone formation in combination with bone resorption in reactive ... With oral osteoporosis, the emphasis should be on good nutrient absorption and metabolic wastes elimination through a healthy ... Heavy metals such as lead and cadmium have been implicated in osteoporosis. Cadmium and lead promotes the synthesis of ... In cases of advanced oral ischaemic osteoporosis and/or ONJ that are not bisphosphonates related, clinical evidence has shown ...
Lumleian Lectures
Cooks, A. M. (1955). "Osteoporosis". The Lancet. 265 (6871): 929-937. doi:10.1016/S0140-6736(55)90963-6. PMID 14368910. Jones, ...
Renal osteodystrophy
"Osteoporosis". The Lecturio Medical Concept Library. Retrieved 27 August 2021. staff, familydoctor org editorial. "What Is ... osteoporosis osteopenia osteomalacia brown tumor should be considered as the top-line diagnosis if a mass-forming lesion is ...
Alkaline phosphatase
Szulc P, Seeman E, Delmas PD (2000). "Biochemical measurements of bone turnover in children and adolescents". Osteoporosis ... Value of the study of total alkaline phosphatases and bone isoenzyme in a population of subjects with osteoporosis]". Annales ... Biliary obstruction Bone conditions Osteoblastic bone tumors Osteomalacia Osteoporosis Hepatitis Cirrhosis Acute cholecystitis ...
VPS13B
"Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians". Osteoporosis ... Studies have also linked mutations in the VPS13B gene to osteoporosis. An association between an increase of the VPS13B copy ...
Vertebral compression fracture
In addition, bone density measurement may be performed to evaluate for osteoporosis. When a tumor is suspected as the ... Compression fractures which develop gradually, such as in osteoporosis, may initially not cause any symptoms, but will later ... 2011). "Balloon kyphoplasty and vertebroplasty in the management of vertebral compression fractures". Osteoporosis ... Osteoporosis International. 16 (10): 1281-90. doi:10.1007/s00198-004-1798-8. PMID 15614441. S2CID 34208503. Taylor, Rod S.; ...
Single photon absorptiometry
... is the first quantitative analysis method used in the diagnosis of osteoporosis. To evaluate bone ... Osteoporosis International. 5 (5): 377-381. doi:10.1007/bf01622260. ISSN 0937-941X. PMID 8800788. S2CID 11127198. Meema, Erik H ... invented by Cameron and Sorenson was the first quantitative analysis method applied to the diagnosis of osteoporosis. This ... simple and sensitive method for early diagnosis and prevention of osteoporosis. Generally speaking, the single photon ...
Leptin
Hamrick MW, Ferrari SL (July 2008). "Leptin and the sympathetic connection of fat to bone". Osteoporosis International. 19 (7 ... and osteoporosis. Other rare polymorphisms have been found but their association with obesity are not consistent. A single case ... "Association of polymorphisms in the leptin and leptin receptor genes with inflammatory mediators in patients with osteoporosis ...
Methylprednisolone
"Osteoporosis Overview , NIH Osteoporosis and Related Bone Diseases National Resource Center". www.bones.nih.gov. Retrieved 7 ... Osteoporosis is a type of bone disease characterized by a loss of bone density, mass and architecture that leaves a patient ... The prevalence of osteoporosis in patients with SLE varies geographically and some attribute it to BMD and T-score diagnostic ... Exogenous corticosteroids induce osteoporosis by increasing bone resorption and reducing bone formation. Bone loss can be ...
Exercise medicine
... osteoporosis, back pain, diabetes, depression and other mental illnesses and falls in the elderly. Exercise has been shown to ... Osteoporosis International. 33 (7): 1415-1427. doi:10.1007/s00198-022-06357-3. PMC 8881760. PMID 35218402. Hayden, JA; Ellis, J ...
Shift work sleep disorder
Osteoporosis International. 20 (4): 537-42. doi:10.1007/s00198-008-0729-5. PMC 2651998. PMID 18766292. Wickwire EM, Geiger- ...
Orthopedic pathology
As a common bone disorder, osteoporosis affects a large section of the population, resulting in a reduced quality of life, ill ... Office of the Surgeon General (US). "Medications that can Cause Bone Loss, Falls and/or Fractures , Osteoporosis Canada". 4 ... These consist of genetic diseases, osteoporosis, infections of the bone, and Paget's disease of bone. Neuromotor impairments ... "Medical Conditions that can Cause Bone Loss, Falls and/or Fractures , Osteoporosis Canada". 4 October 2017. Retrieved 2020-06- ...
Bone resorption
Some diseases with symptoms of decreased bone density are osteoporosis, and rickets. Some people who experience increased bone ... Osteoporosis International. 20 (9): 1529-1538. doi:10.1007/s00198-009-0836-y. ISSN 1433-2965. PMID 19238309. S2CID 11502836. ... prolonged ethanol exposure increases fracture risk by decreasing bone mineral density and promoting osteoporosis. Indirect ... adding weight-bearing exercise versus nonweight bearing programs to the medical treatment of elderly patients with osteoporosis ...
Alendronic acid
Prevention and treatment of female osteoporosis Treatment of male osteoporosis Prevention and treatment of corticosteroid- ... "Severe Pain with Osteoporosis Drugs". FDA Patient Safety News. March 2008. Archived from the original on 15 April 2014. " ... Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and ... Lay summary in: Gardner A (December 31, 2008). "Osteoporosis Drug Prompts Increase in Certain Bone Cells". Washington Post. ...
Acid ash hypothesis
However, this acceptance of the acid-ash hypothesis as a major modifiable risk factor of osteoporosis by these publications was ... This review found no significant evidence suggesting dairy product intake causes acidosis or increases risk for osteoporosis. A ... Consequently, "alkaline ash" (alkaline producing) elements would hypothetically decrease the risk of osteoporosis. This ... including an increased risk of osteoporosis. It has received some attention in the lay community, and has been used to support ...
Stuart Palmer (physicist)
While working at the University of Hull he led a team applying ultrasound to the diagnosis and monitoring of osteoporosis. This ... Osteoporosis International. 6 (6): 471-479. doi:10.1007/BF01629580. ISSN 0937-941X. PMID 9116393. S2CID 26081955. Scruby, C. B ... led to an ultrasonic index for osteoporosis and the development of commercial ultrasound heel scanners that are available ...
Hypophosphatasia
Colazo JM, Hu JR, Dahir KM, Simmons JH (February 2019). "Neurological symptoms in Hypophosphatasia". Osteoporosis International ... September 2017). "Clinical, radiographic and biochemical characteristics of adult hypophosphatasia". Osteoporosis International ... Osteoporosis International. 32 (2): 377-385. doi:10.1007/s00198-020-05612-9. PMC 7838076. PMID 32879991. Zurutuza L, Muller F, ...
Women's Health Initiative
August 2002). "Meta-analyses of therapies for postmenopausal osteoporosis. VII. Meta-analysis of calcium supplementation for ... and osteoporosis are the leading causes of morbidity and mortality, as well as impaired quality of life. Among women in all age ... and osteoporosis.[citation needed] In its entirety, the WHI enrolled more than 160,000 postmenopausal women aged 50-79 years ( ... Osteoporosis International. 24 (2): 567-580. doi:10.1007/s00198-012-2224-2. PMC 3557387. PMID 23208074. Chlebowski RT, Johnson ...
Fish scale
"Prednisolone induces osteoporosis-like phenotype in regenerating zebrafish scales". Osteoporosis International. 25 (2): 567-578 ... Bergen, Dylan J. M.; Kague, Erika; Hammond, Chrissy L. (2019). "Zebrafish as an Emerging Model for Osteoporosis: A Primary ...
Osteocalcin
Osteoporosis International. 20 (9): 1603-11. doi:10.1007/s00198-009-0839-8. PMID 19172341. S2CID 10711802. Kamdem LK, Hamilton ... "Changes of bone formation markers osteocalcin and bone-specific alkaline phosphatase in postmenopausal women with osteoporosis ... well correlated with increases in bone mineral density during treatment with anabolic bone formation drugs for osteoporosis, ...
No data available that match "osteoporosis"
FractureBonesDevelop osteoporosisInternational Osteoporosis FoundationPostmenopausal women with osteoporosisTreat osteoporosis2020Prevention20172022People with osteoporosisDevelopment of osteoporosisAffectsSpineCauses of OsteoporosisFamily history of osteoporosisPrevalenceScreening in postmenopausal womenPorous bonePrevent fracturesBisphosphonatesOccursTreatmentFractures due to osteoporosisWomenOsteoarthritisIncrease the risk of osteoporosisHealthPreventable diseaseCalciumIncreasesEstrogenMenopauseLikely to have osteoporosisGreater risk for osteoporosisOsteopeniaHormoneOsteomalaciaProstate cancerSubsequent fracturesRates of osteoporosisSuffer from osteoporosisSymptoms of osteoporosisKnowledge of osteoporosisAlready have osteoporosisDEXA
Fracture44
- Osteoporosis causes bones to become weak and brittle - so brittle that a fall or even mild stresses such as bending over or coughing can cause a fracture. (mayoclinic.org)
- Osteoporosis is a disease in which bones become fragile and more likely to break (fracture). (medlineplus.gov)
- Osteoporosis has been diagnosed by a bone density study , whether or not you have a fracture, and your fracture risk is high. (medlineplus.gov)
- You have had a bone fracture, and a bone density test shows that you have thin bones, but not osteoporosis. (medlineplus.gov)
- One out of every two women and one in four men over 50 will have an osteoporosis-related fracture in their lifetime. (livescience.com)
- People may not know they have osteoporosis until their bones become so weak that a bump or fall causes a hip to fracture or a vertebra to collapse. (livescience.com)
- What's more, few older men are on the alert for osteoporosis, even though one in five will have a fracture. (news24.com)
- Osteoporosis is sometimes called the "silent disease," and most people don't know they have osteoporosis until it has progressed, often to the point of fracture, usually in the hip, wrist or spine. (spine-health.com)
- Even when undiagnosed osteoporosis results in a vertebral fracture , the pain is frequently dismissed as general back pain. (spine-health.com)
- high dietary calcium suppresses age-related bone loss and reduces fracture rate in patients w/ osteoporosis. (wheelessonline.com)
- Postmenopausal osteoporosis is a silent disease that affects millions of women, making their bones weak and more likely to fracture over time. (news-medical.net)
- In fact, in the U.S. today, 8 million women are estimated to already have osteoporosis, and almost 27 million more are estimated to have low bone mass, placing them at increased risk for fracture. (news-medical.net)
- Usually, a person will sustain a fracture before they find out that they suffer from osteoporosis but by that time the disease may be in its advanced stages and the damage may be serious. (com.pk)
- The bone health specialists at UC San Diego Health help ensure that anyone who incurs a hip fracture as a result of a fall from a standing height or less will receive a fracture risk assessment, treatment (if necessary), and continued care from an orthopedist and osteoporosis specialist. (ucsd.edu)
- Geriatricians regularly treat osteoporosis since age is the single-greatest risk factor for sustaining an osteoporotic fracture. (ucsd.edu)
- If you answered "yes" to any of these questions, you need to take the time and read this article as one in every two Caucasian women in the US will experience an osteoporosis-related fracture in her lifetime. (arizonafoothillsmagazine.com)
- There also are several medications available for treating osteoporosis that can help to rebuild and strengthen bone and reduce fracture risk. (cooperhealth.org)
- If you are a 50 year-old woman, you have a 50-50 chance of suffering a bone fracture related to osteoporosis during your lifetime. (coxhealth.com)
- Rationale: The USPSTF found good evidence that the risk for osteoporosis and fracture increases with age and other factors, that bone density measurements accurately predict the risk for fractures in the short-term, and that treating asymptomatic women with osteoporosis reduces their risk for fracture. (uspreventiveservicestaskforce.org)
- Rationale: The USPSTF found fair evidence that screening women at lower risk for osteoporosis or fracture can identify additional women who may be eligible for treatment for osteoporosis, but it would prevent a small number of fractures. (uspreventiveservicestaskforce.org)
- Modeling analysis suggests that the absolute benefits of screening for osteoporosis among women aged 60-64 who are at increased risk for osteoporosis and fracture are comparable to those of routine screening in older women. (uspreventiveservicestaskforce.org)
- In 2012, guidelines published by the Veterans Health Administration (VHA) identified osteoporosis as a major health issue in men because their risk of illness and death following a hip fracture is greater than for women. (thedoctorwillseeyounow.com)
- A fracture risk of three percent or greater puts a person over the minimum threshold for treatment with vitamin D and bisphosphonates, a class of drugs prescribed for osteoporosis. (thedoctorwillseeyounow.com)
- The team found that nearly half - 48 percent - of men between the ages of 75 and 79 years old who had only age as a risk factor for osteoporosis had a 10-year hip fracture risk of three percent or greater, making it clear how common osteoporosis is among men. (thedoctorwillseeyounow.com)
- As the authors write, "There is a need for developing strategies to improve the evaluation and management of osteoporosis in all older men, particularly among those with a very high risk of fracture. (thedoctorwillseeyounow.com)
- Osteoporosis is a serious problem with 50% of women and 25% of men over the age of 50 suffering a fracture because of it. (thenakedscientists.com)
- Fracture outcome definitions in observational osteoporosis d. (lww.com)
- The objective of this review is to describe fracture outcome definitions in observational osteoporosis drug effects studies from Canada and the United States. (lww.com)
- We will include observational studies from the United States and Canada that consider the impact of osteoporosis pharmacotherapies on fracture risk and leverage health care administrative data. (lww.com)
- Osteoporosis is a debilitating brittle bone disease characterized by low bone-mineral density and increased fracture risk. (lww.com)
- 3 Health care administrative databases are commonly used to measure fracture prevalence and to help determine osteoporosis drug effectiveness (eg, on femoral neck, radius/ulna, vertebral fractures) and safety (eg, atypical femoral fracture). (lww.com)
- Homeopathic preparation used to relieve post fracture pain associated with osteoporosis or traumas. (rediscoverhealth.ca)
- Having a parent or sibling with osteoporosis puts you at greater risk, especially if your mother or father experienced a hip fracture. (youchoimd.net)
- One in three women and one in five men will develop a fracture as a result of osteoporosis. (osteoporosis.org.za)
- Osteoporosis is a disease in which the density and quality of bones are reduced, leading to weakness of the skeleton and increased risk of fracture, particularly of the spine, wrists, hip, pelvis and upper arms. (osteoporosis.org.za)
- Whether you are already diagnosed with osteoporosis or you are unaware you are at risk, a fracture may well become a reality - sometimes caused by a simple misadventure that in a younger, stronger boned person would not cause a problem. (osteoporosis.org.za)
- osteoporosis, osteoporotic fracture, osteoporosis management. (healthplexus.net)
- Many people have no signs of osteoporosis until a fracture has occurred, making it a silent illness. (verywellhealth.com)
- Osteoporosis is a condition in which the bones become less dense and more likely to fracture. (trellushealth.net)
- Sometimes a patient's first fracture is the sentinel event that alerts the clinician to an underlying disorder leading to osteoporosis. (medscape.com)
- Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. (medscape.com)
- Having low bone mineral density doesn't necessarily mean that you will develop osteoporosis or have a fracture. (aidsmap.com)
- According to the Osteoporosis Canada, 2 Million Canadians are affected by osteoporosis and at least 1 in 3 women and 1 in 5 men will suffer from an osteoporotic fracture during their lifetime. (medgadget.com)
- This guideline covers assessing the risk of fragility fracture in people aged 18 and over with osteoporosis. (bvsalud.org)
Bones25
- However, simple x-rays of other bones are not very accurate in predicting whether you are likely to have osteoporosis. (medlineplus.gov)
- Osteoporosis is a systemic disease that gradually weakens the bones, leading to painful and debilitating fragility fractures (broken bones). (news24.com)
- Osteoporosis is a progressive bone disease that weakens the bones and increases the risk of fractures. (nationaljewish.org)
- Osteoporosis is a thinning of the bones that causes them to become porous and fragile. (spine-health.com)
- Osteoporosis is a disease that affects your bones. (healthwise.net)
- Osteoporosis can lead to broken bones (fractures) in the hip, spine, and wrist. (healthwise.net)
- Osteoporosis is characterised by low bone mass and loss of bone tissue that leads to weak and fragile bones. (com.pk)
- Mrs Shahid, a 55-year-old, who has been battling with osteoporosis after her menopause faces great difficulty in walking due to her weak bones. (com.pk)
- Osteoporosis is defined as: a medical condition in which the bones become brittle and fragile from loss of tissue, typically as a result of hormonal changes, or deficiency of calcium or vitamin D. (arizonafoothillsmagazine.com)
- The bones most often affected by osteoporosis are the hips, spine and wrists. (cooperhealth.org)
- Osteopenia is a condition in which your bones are weaker and less dense than normal, but they aren't so brittle that they break easily, as in osteoporosis. (cooperhealth.org)
- Also known as bone loss or porous bone, Osteoporosis is a well-known condition in which bones become weaker and more susceptible to fractures. (uclahealth.org)
- Black Bears seem to be unique amongst hibernating animals because they have the unique ability to stop their bones from thinning during their long winter sleep, suggesting that they may hold the key to preventing bone thinning diseases, like osteoporosis, in humans. (thenakedscientists.com)
- Osteoporosis is a long-term (chronic) disease that slowly weakens bones until they break easily. (comportho.com)
- The exact role tobacco plays in osteoporosis isn't clearly understood, but it has been shown that tobacco use contributes to weak bones. (youchoimd.net)
- Osteoporosis is a disease that causes bones to become weak and brittle. (nih.gov)
- You can take steps to help prevent osteoporosis and broken bones by: Doing weight-bearing exercises, such as walking or dancing, and lifting weights. (nih.gov)
- Osteoporosis has been called a childhood disease with old-age consequences because building healthy bones in youth helps prevent osteoporosis and fractures later in life. (trellushealth.net)
- Milk and Osteoporosis - Is Dairy Good for Your Bones? (iytmed.com)
- Osteoporosis is a progressive illness in which bones deteriorate, losing mass and minerals gradually. (iytmed.com)
- The name is extremely detailed of the nature of the illness: osteoporosis = porous bones. (iytmed.com)
- Osteoporosis may be confused with osteomalacia, but in osteoporosis the bones are porous and brittle, whereas in osteomalacia the bones are soft. (medscape.com)
- Teriparatide injection is used to treat osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause ('change in life,' end of menstrual periods), who are at high risk of fractures (broken bones), and cannot use other osteoporosis treatments. (medlineplus.gov)
- It is also used to increase bone mass in men with certain types of osteoporosis who are at high risk for having broken bones (fractures), and who cannot use other osteoporosis treatments. (medlineplus.gov)
- Teriparatide injection is also used to treat osteoporosis in men and women who are taking corticosteroids (a type of medication that may cause osteoporosis in some patients) who are at high risk of fractures (broken bones), and cannot use other osteoporosis treatments. (medlineplus.gov)
Develop osteoporosis6
- How likely you are to develop osteoporosis depends partly on how much bone mass you attained in your youth. (mayoclinic.org)
- The higher your peak bone mass, the more bone you have "in the bank" and the less likely you are to develop osteoporosis as you age. (mayoclinic.org)
- A number of factors can increase the likelihood that you'll develop osteoporosis - including your age, race, lifestyle choices, and medical conditions and treatments. (mayoclinic.org)
- Women are much more likely to develop osteoporosis than are men. (mayoclinic.org)
- While often a precursor to osteoporosis, not everyone with osteopenia will develop osteoporosis. (spine-health.com)
- As a result, women develop osteoporosis far more often than men. (healthwise.net)
International Osteoporosis Foundation4
- According to a report published by the International Osteoporosis Foundation (IOF) in 2006, women in Pakistan have a daily calcium intakes of 300 to 500 milligrams range which is less than the ideal intake of 1000 milligrams. (com.pk)
- The members of the Committee of Scientific Advisors of the International Osteoporosis Foundation ( IOF ) and the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis ( ESCEO ) are developing a very exciting Congress' scientific programme that will bring together the world's best in the field of musculoskeletal health and disease. (wco-iof-esceo.org)
- Czerwinski E, Badurski JE, Marcinowska-Suchowierska E, Osieleniec J. Current understanding of osteoporosis according to the position of the World Health Organization (WHO) and International Osteoporosis Foundation. (medscape.com)
- According to recent statistics from the International Osteoporosis Foundation, worldwide, 1 in 3 women over the age of 50 years and 1 in 5 men will experience osteoporotic fractures in their lifetime. (medgadget.com)
Postmenopausal women with osteoporosis3
- Actonel is approved to reduce the risk of fractures in postmenopausal women with osteoporosis. (news-medical.net)
- Denosumab for preventing fractures in postmenopausal women with osteoporosis New is a topic covered in the Cochrane Abstracts . (unboundmedicine.com)
- Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/439926/all/Denosumab_for_preventing_fractures_in_postmenopausal_women_with_osteoporosis_New. (unboundmedicine.com)
Treat osteoporosis4
- Bisphosphonates -- the main drugs used to prevent and treat osteoporosis in postmenopausal women. (medlineplus.gov)
- 1 Several agents have been used for many years to prevent or treat osteoporosis. (bmj.com)
- Bisphosphonates are potent inhibitors of resorption and represent 70% of the worldwide market for drugs used to treat osteoporosis. (bmj.com)
- You can treat osteoporosis through diet and other lifestyle changes. (ucsd.edu)
20201
- American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. (medscape.com)
Prevention7
- 1975). Prevention of rickets, osteomalacia and osteoporosis. (who.int)
- Many osteoporosis treatment tools are similar to prevention methods, such as recommending changes to diet and lifestyle. (hopkinsmedicine.org)
- The U.S. Food and Drug Administration (FDA) approved a new once-a-month dose (150 mg) of Actonel (risedronate sodium) tablets for the treatment and prevention of postmenopausal osteoporosis. (news-medical.net)
- Might fruits and vegetables be the unexpected natural answer to the question of osteoporosis prevention? (nutritionfacts.org)
- Osteoporosis is a lifestyle disease and prevention is the best cure. (osteoporosis.org.za)
- Clinician's Guide to Prevention and Treatment of Osteoporosis. (medscape.com)
- 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. (medscape.com)
20171
- According to the U.S. Department of Health and Human Services Offices of Women's Health (HHS-OWH 2017), of the 10 million people in the US with osteoporosis, 8 million are female. (arizonafoothillsmagazine.com)
20221
- Fast Five Quiz: Osteoporosis Myths vs Facts - Medscape - Aug 19, 2022. (medscape.com)
People with osteoporosis8
- For people with osteoporosis, bone loss (resorption) outpaces the growth (remodeling) of new bone. (news24.com)
- A new study suggests that certain yoga poses can lead to bone injuries in people with osteoporosis or osteopenia. (medicalnewstoday.com)
- In order to verify the link between the practice of yoga and the experience of additional injuries in people with osteoporosis, the research team analyzed the health records of 89 individuals. (medicalnewstoday.com)
- People with osteoporosis should walk at least 30 minutes daily, use your treadmill while you are watching television, jog, play tennis, do weight training, dance or any exercise that does not present the risk of falling. (safemenopausesolutions.com)
- Major risk factors of osteoporosis and what should people with osteoporosis do about it! (safemenopausesolutions.com)
- 4 - People with osteoporosis that have family history or genetic predisposition. (safemenopausesolutions.com)
- 11 - People with osteoporosis have insufficient calcium absorption and they should supplement their diet with vitamins, minerals, and other nutrients and herbs with the purpose of preventing osteoporosis. (safemenopausesolutions.com)
- Taking medication, if prescribed, can help prevent fractures in people with osteoporosis. (theinfotree.com)
Development of osteoporosis4
- Because excessive free radicals may contribute to bone loss, it's important to elucidate the potential role antioxidant-rich fruits play in mitigating the bone loss that leads to the development of osteoporosis. (nutritionfacts.org)
- For example, the use of certain drugs has been associated with the development of osteoporosis. (medscape.com)
- A lifelong lack of calcium plays a major role in the development of osteoporosis. (youchoimd.net)
- Having too much salt leads to an increasing in the elimination of calcium, which helps the development of osteoporosis. (botanical-online.com)
Affects7
- Osteoporosis affects men and women of all races. (mayoclinic.org)
- Osteoporosis affects more than 10 million Americans. (hopkinsmedicine.org)
- Osteoporosis affects millions of older adults. (healthwise.net)
- Video presents an overview of understanding how osteoporosis affects individuals with a spinal cord injury (SCI). (naric.com)
- 9 - Cigarette smoking affects hormone imbalance and osteoporosis. (safemenopausesolutions.com)
- Although it is a preventable disease, osteoporosis affects an estimated 25 million people worldwide, leading to 1 million fractures, 40 000 annual deaths and health costs of billions of dollars [4-6]. (who.int)
- Osteoporosis mainly affects women. (comportho.com)
Spine12
- Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. (mayoclinic.org)
- Any bone can break due to osteoporosis, but some of the most serious and common fractures are those of the spine and hip. (news24.com)
- Hip fractures may occur less in our black population, but osteoporosis in the spine and subsequent spine fractures seems to occur equally in all race groups. (news24.com)
- A new NCHS Health E-Stat provides information on the percentage of U.S. adults aged 65 and over with osteoporosis and low bone mass at the femur neck or lumbar spine, using data from the 2005-2010 National Health and Nutrition Examination Survey. (cdc.gov)
- Key exercises for osteoporosis target the spine and hips, where fractures are most likely to occur. (qualityhealth.com)
- If you have osteoporosis, don't allow a therapist to deep massage near your spine. (dummies.com)
- Bone fractures, particularly in the spine or hip, are the most serious complication of osteoporosis. (youchoimd.net)
- Hip, wrist, or spine fractures are usually associated with osteoporosis. (theinfotree.com)
- Osteoporosis is a systemic disease that causes the skeleton to become porous and brittle and this can lead to fractures of the forearm, spine and hip. (osteoporosis.org.za)
- Osteoporosis is a chronic, debilitating disease that is most distressing to patients and health care providers in the occurrence of fractures of the hip and spine. (healthplexus.net)
- Osteoporosis is defined as a bone mineral density of 2.5 standard deviations or more below the mean value for a young woman at either the femur neck or the lumbar spine, or both locations, as measured by dual energy x-ray absorptiometry. (cdc.gov)
- Radiographs of the pelvis and lumbosacral spine reveal pseudofractures and other evidence of severe osteomalacia and mild osteoporosis. (cdc.gov)
Causes of Osteoporosis1
- Topics include: what osteoporosis is, bony anatomy, osteoporosis and SCI, fractures and SCI, causes of osteoporosis in SCI, treatment of fractures in SCI, medications and exercises for osteoporosis, and recommendations. (naric.com)
Family history of osteoporosis1
- Do you have a family history of osteoporosis? (comportho.com)
Prevalence4
- Despite the wide prevalence of osteoporosis, no proper cure has been found yet. (com.pk)
- Furthermore, new studies have shown the prevalence of osteoporosis in men is higher than previously thought with approximately one in five men affected. (osteoporosis.org.za)
- Growing prevalence of bone related diseases such as osteoporosis is driving growth of the external fixators market. (medgadget.com)
- North America is expected to gain significant growth over the forecast period owing to the high prevalence of osteoporosis in the region. (medgadget.com)
Screening in postmenopausal women1
- The USPSTF makes no recommendation for or against routine osteoporosis screening in postmenopausal women who are younger than 60 or in women aged 60-64 who are not at increased risk for osteoporotic fractures. (uspreventiveservicestaskforce.org)
Porous bone2
- Osteoporosis, or porous bone, is a disease characterized by low bone mass and structural deterioration of bone tissue. (livescience.com)
- Osteoporosis means porous bone. (cooperhealth.org)
Prevent fractures1
- Early treatment of osteoporosis and osteopenia can ease pain, limit or halt bone loss, and prevent fractures. (hopkinsmedicine.org)
Bisphosphonates3
- Updated ) Osteoporosis drugs including oral bisphosphonates show efficacy and safety in the treatment of bone loss in patients with chronic kidney disease (CKD) in several observational studies. (medscape.com)
- Most cases were reported in cancer patients receiving intravenous bisphosphonates, but some have been in patients treated orally for osteoporosis. (news-medical.net)
- The most commonly prescribed medications for osteoporosis are antiresorptive drugs, known as bisphosphonates. (ucsd.edu)
Occurs5
- Osteoporosis occurs when the creation of new bone doesn't keep up with the loss of old bone. (mayoclinic.org)
- You may need blood and urine tests if your provider thinks the cause of your osteoporosis is a medical condition, rather than the slow bone loss that occurs with aging. (medlineplus.gov)
- When those components are lost too rapidly or not replenished quickly enough (or both), osteoporosis occurs. (hopkinsmedicine.org)
- The bone loss that occurs as part of osteoporosis is progressive (it continues over time), and there often are no symptoms until a bone breaks. (cooperhealth.org)
- Osteoporosis occurs when extra bone mass is lost and bone tissue changes. (theinfotree.com)
Treatment14
- Effects of Kisspeptin on Bone Metabolism in Healthy Men The beneficial effects of kisspeptin on bone metabolism could lead to a potentially exciting new role for this hormone in the treatment of osteoporosis. (medscape.com)
- BMD tests can identify osteoporosis, determine your risk for fractures, and measure your response to osteoporosis treatment. (livescience.com)
- A comprehensive osteoporosis treatment program includes a focus on proper nutrition, exercise , and safety issues to prevent falls that may result in fractures. (livescience.com)
- Treatment for osteoporosis includes medicine to reduce bone loss and to build bone strength. (healthwise.net)
- The standard of care for treating osteoporosis has changed since 2008, when treatment recommendations were based solely on a person's bone mineral density. (ucsd.edu)
- A modestly increased risk for atrial fibrillation was seen during the first year of treatment with zoledronic acid (Reclast) for osteoporosis, and a nonsignificant trend toward an increased risk when the drug was used for malignancy-related bone disease, a researcher reported. (medpagetoday.com)
- It's especially important for osteoporosis treatment to add green leafy vegetables to your diet. (safemenopausesolutions.com)
- Women are much more likely to be screened and treated for osteoporosis than men of the same age, researchers at the University of Washington found, concluding that, "Current guidelines are inadequate for identifying men who would benefit from osteoporosis evaluation and preventive treatment. (thedoctorwillseeyounow.com)
- The study compared rates of osteoporosis testing and treatment in men and women 70 years old or older receiving care at a Veterans Affairs (VA) medical center. (thedoctorwillseeyounow.com)
- But if this does pan out for other plants, a "fruit and vegetables" approach may provide a very sensible (and natural) alternative therapy for osteoporosis treatment, one that is likely to have numerous additional health-related benefits. (nutritionfacts.org)
- Finding a healthcare provider that specializes in osteoporosis can make a big difference when seeking a diagnosis and treatment options. (verywellhealth.com)
- Treatment for osteoporosis is related to drug discovery alternative to hormone therapy estrogen offset the disadvantages of this therapy. (bvsalud.org)
- The aims of this review were report the effect of the osteoporosis on the alveolar bone and demonstrate the efficacy of the therapies currently used for treatment of this disease, emphasizing studies on the Selective Estrogen Receptor Modulators and the sodium fluoride. (bvsalud.org)
- The review was divided into 3 topics: (1) Bone metabolism, (2) Effects of the osteoporosis on the alveola bone, (3) Therapies used for treatment of the osteoporosis. (bvsalud.org)
Fractures due to osteoporosis1
- Various nonpharmacological modalities may be used adjunctively with prescribed agents to improve the quality of life of patients with fractures due to osteoporosis. (healthplexus.net)
Women27
- The fall in estrogen levels in women at menopause is one of the strongest risk factors for developing osteoporosis. (mayoclinic.org)
- This means that at age 80, almost one third of women with normal age-related bone loss would have osteoporosis, based on their DEXA scan results. (medlineplus.gov)
- Yes, men do get osteoporosis, but women are at greater risk. (livescience.com)
- Up to 1 in 2 women will break a bone due to osteoporosis - equal to the risk of breast, ovarian and uterine cancer combined. (hopkinsmedicine.org)
- So the older women get, the more likely they are to have osteoporosis. (healthwise.net)
- Osteoporosis is much more common in women than in men. (healthwise.net)
- The leading cause of osteoporosis is a lack of certain hormones, particularly estrogen in women and androgen in men. (com.pk)
- Women, especially those older than 60 years of age, are frequently diagnosed with osteoporosis. (com.pk)
- Osteoporosis is often considered to be a condition limited to frail elderly women. (com.pk)
- Osteoporosis and low bone mass (a condition called osteopenia) are a major public health problem for an estimated 44 million U.S. women and men aged 50 and older. (cooperhealth.org)
- Of the approximately 10 million Americans who currently have osteoporosis, 80% are women. (cooperhealth.org)
- As a result, about one in two women over age 50 will break a bone due to osteoporosis. (cooperhealth.org)
- The main cause of osteoporosis is a low level of hormones, particularly estrogen in women and testosterone in men. (cooperhealth.org)
- Postmenopausal women are frequently diagnosed with osteoporosis because menopause is accompanied by a sharp drop in estrogen levels. (cooperhealth.org)
- Eighty percent of those affected by osteoporosis are women, but younger women and men can also be at risk. (coxhealth.com)
- The U.S. Preventive Services Task Force (USPSTF) recommends that women aged 65 and older be screened routinely for osteoporosis. (uspreventiveservicestaskforce.org)
- Preventing osteoporosis is crucial for men and women! (safemenopausesolutions.com)
- Men and women that are very thin, chronically underweight and have eating disorders are at risk for osteoporosis. (safemenopausesolutions.com)
- 3 - Caucasian and Asian women are more likely to get osteoporosis and lower bone density. (safemenopausesolutions.com)
- 8 - Women that experience a hysterectomy and have their ovaries removed could experience osteoporosis as a side effect of hysterectomy. (safemenopausesolutions.com)
- It's not clear why men in the U.S. do not get tested and screened for osteoporosis as they age the way women do. (thedoctorwillseeyounow.com)
- An estimated 1 in 2 women and 1 in 8 men over the age of 50 years will have osteoporosis-related fractures in their lifetime [3,6]. (who.int)
- One in 2 U.S. women and 1 in 4 U.S. men older than 50 will have a broken bone at some point in their life because of osteoporosis. (comportho.com)
- In South Africa, 1 in 3 women and 1 in 5 men will possibly develop this disease within their lifetime - which means potentially between 4 and 6 million South Africans suffer from Osteoporosis. (osteoporosis.org.za)
- Osteoporosis causes more than 8.9 million fractures globally each year, and research estimates that around 40% of women and 30% of men will experience osteoporosis-related fractures. (verywellhealth.com)
- Osteoporosis is far more typical in women than in men, especially after menopause. (iytmed.com)
- Routine screening for osteoporosis in men is not as widespread a practice as is screening in women. (medscape.com)
Osteoarthritis1
- Osteoarthritis, osteoporosis, or other. (cdc.gov)
Increase the risk of osteoporosis2
- Certain medications (prednisone, e.g.) and diseases can also cause bone loss and increase the risk of osteoporosis. (hopkinsmedicine.org)
- some risks may cause or increase the risk of osteoporosis. (theinfotree.com)
Health9
- Cooper University Health Care has a skilled team of board-certified specialists with extensive expertise in diagnosing and treating osteoporosis. (cooperhealth.org)
- In addition to taking the appropriate foods for osteoporosis, the following recommendations should be followed to improve the assimilation of the nutrients in the diet and the health of the organism. (botanical-online.com)
- Men and women's bodies need nutritious food and a quality vitamin/mineral supplement to improve and maintain our health and preventing osteoporosis. (safemenopausesolutions.com)
- Fluoride can affect osteoporosis and your health. (safemenopausesolutions.com)
- It is our hope that National Osteoporosis Month motivates everyone to take simple steps toward improving their bone health and living active, independent lives. (womenfitness.net)
- We urgently need public health strategies to maintain bone health, and prevent osteoporosis. (nutritionfacts.org)
- Osteoporosis can lead to fractures, pain, and mental health problems. (verywellhealth.com)
- Finding the right healthcare provider, working with a mental health professional, and participating in an osteoporosis support group can help. (verywellhealth.com)
- The Bone Health and Osteoporosis Foundation also offers online medical professional search tools. (verywellhealth.com)
Preventable disease1
- Although osteoporosis is a preventable disease affecting millions of people, public awareness remains low. (who.int)
Calcium6
- Other factors that can contribute to developing osteoporosis are a lack of dietary calcium and vitamin D, a sedentary lifestyle, thyroid and other medical conditions, smoking and chronic alcohol use. (cooperhealth.org)
- Solutions for preventing osteoporosis are exercise, calcium supplements and natural progesterone supplementation. (safemenopausesolutions.com)
- If you are experiencing osteoporosis, you could benefit a great deal by taking a quality multiple vitamin/mineral and a calcium supplement. (safemenopausesolutions.com)
- Calcium deficiency also effects the heart and circulatory system, as well as the secretion of essential hormones and preventing osteoporosis. (safemenopausesolutions.com)
- 12 - Hypothyroidism, excessive thyroid medication, antibiotics, certain cancer treatments, treatments for endometriosis and corticosteroid medication can all impair calcium absorption and be major risk factors of osteoporosis. (safemenopausesolutions.com)
- In spite of all the calcium that dairy includes, some believe that its high protein content can cause osteoporosis. (iytmed.com)
Increases4
- Osteoporosis increases the risk of breaking a bone. (medlineplus.gov)
- Menopause is accompanied by lower estrogen levels and increases a woman's risk of osteoporosis. (com.pk)
- Having osteopenia increases your risk of developing osteoporosis. (cooperhealth.org)
- Regular consumption of more than two alcoholic drinks a day increases your risk of osteoporosis. (youchoimd.net)
Estrogen1
- 4 , 5 Low weight and no current use of estrogen therapy are incorporated with age into the 3-item Osteoporosis Risk Assessment Instrument (ORAI). (uspreventiveservicestaskforce.org)
Menopause2
- You might want to talk to your doctor about osteoporosis if you went through early menopause or took corticosteroids for several months at a time, or if either of your parents had hip fractures. (mayoclinic.org)
- 2 - Osteoporosis usually accelerates during menopause, but it could begin 30 years prior to menopause. (safemenopausesolutions.com)
Likely to have osteoporosis1
- You are more likely to have osteoporosis if you didn't reach your ideal bone density during your childhood and teen years. (healthwise.net)
Greater risk for osteoporosis2
- Since a diagnosis of osteopenia puts one at greater risk for osteoporosis, patients are encouraged to seek the advice of their physicians about implementing preventive measures. (spine-health.com)
- People who have an extremely low BMI are at greater risk for osteoporosis than people of normal or high BMI. (comportho.com)
Osteopenia5
- Bone density tests can also identify patients with osteopenia - decreased bone mass that has not yet reached the level of osteoporosis. (hopkinsmedicine.org)
- The new study's findings - featured in the journal Mayo Clinic Proceedings - indicate that certain yoga poses may harm people with osteopenia or osteoporosis, leading to further soft tissue and bone injury. (medicalnewstoday.com)
- The researchers do not discourage people with osteopenia or osteoporosis from practicing yoga. (medicalnewstoday.com)
- But if you have osteoporosis or osteopenia, you should modify the postures to accommodate your condition. (medicalnewstoday.com)
- Osteopenia is a condition where bone mineral density is lower than normal, but not low enough to be classified as osteoporosis. (spine-health.com)
Hormone2
- Natural progesterone can help you re-balance your hormones, reverse osteoporosis and safely reduce or eliminate hormone imbalance symptoms. (safemenopausesolutions.com)
- Natural progesterone is an effective alternative to give your body the hormone balance you need and to reduce or eliminate risk factors of osteoporosis. (safemenopausesolutions.com)
Osteomalacia1
- In osteoporosis, the mineral-to-collagen ratio is within the reference range, whereas in osteomalacia, the proportion of mineral composition is reduced relative to organic matrix content. (medscape.com)
Prostate cancer1
- Up to 1 in 4 men will break a bone due to osteoporosis - a risk greater than prostate cancer. (hopkinsmedicine.org)
Subsequent fractures1
- 1,2 As the world's population ages, osteoporosis and the subsequent fractures will become increasingly common. (lww.com)
Rates of osteoporosis1
- Patients with PD are at greater risk of falls and fractures, and risk of injury is compounded by the high rates of osteoporosis [ 4 - 6 ]. (hindawi.com)
Suffer from osteoporosis1
- Here at Arthritis, Rheumatic & Bone Disease Associates, we treat a number of patients who suffer from osteoporosis or other conditions that feature a lack of bone. (arthritissj.com)
Symptoms of osteoporosis1
- What are the symptoms of osteoporosis? (hopkinsmedicine.org)
Knowledge of osteoporosis2
- In commenting on the research, Michael Econs, MD, a professor in the Indiana University School of Medicine, in Indianapolis, and incoming ASBMR president, said this work offers important insight to add to knowledge of osteoporosis drugs in CKD. (medscape.com)
- Schools can be one of the best venues for increasing knowledge of osteoporosis and inducing lasting behavioural change during adolescence, the period of peak bone density [9,11-13]. (who.int)
Already have osteoporosis1
- In the United States, more than 53 million people either already have osteoporosis or are at high risk due to low bone mass. (trellushealth.net)
DEXA1
- Cooper performs over 2,000 DEXA scans a year-more than any other facility in the region, reflecting the depth of our experience in diagnosing osteoporosis. (cooperhealth.org)