Dissolution of bone that particularly involves the removal or loss of calcium.
Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (HAJDU-CHENEY SYNDROME), or carpal/tarsal.
A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.
Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
Replacement for a hip joint.
Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.
Replacement of the hip joint.
The plan and delineation of prostheses in general or a specific prosthesis.
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an osteoclast and is involved in CEMENTUM resorption.
Bone loss due to osteoclastic activity.
Rare, autosomal dominant syndrome characterized by ACRO-OSTEOLYSIS, generalized OSTEOPOROSIS, and skull deformations.
The part of the pelvis that comprises the pelvic socket where the head of FEMUR joins to form HIP JOINT (acetabulofemoral joint).
An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc. It is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.
A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
Tumors or cancer located in bone tissue or specific BONES.
The joint that is formed by the articulation of the head of FEMUR and the ACETABULUM of the PELVIS.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.
A dark-gray, metallic element of widespread distribution but occurring in small amounts; atomic number, 22; atomic weight, 47.90; symbol, Ti; specific gravity, 4.5; used for fixation of fractures. (Dorland, 28th ed)
The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.
Polymerized methyl methacrylate monomers which are used as sheets, moulding, extrusion powders, surface coating resins, emulsion polymers, fibers, inks, and films (From International Labor Organization, 1983). This material is also used in tooth implants, bone cements, and hard corneal contact lenses.
The joining of objects by means of a cement (e.g., in fracture fixation, such as in hip arthroplasty for joining of the acetabular component to the femoral component). In dentistry, it is used for the process of attaching parts of a tooth or restorative material to a natural tooth or for the attaching of orthodontic bands to teeth by means of an adhesive.
Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.
Biocompatible materials usually used in dental and bone implants that enhance biologic fixation, thereby increasing the bond strength between the coated material and bone, and minimize possible biological effects that may result from the implant itself.
Partial or total replacement of a joint.
Replacement for a knee joint.
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.
The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis.
Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999)
Inflammation of the bone.
X-RAY COMPUTERIZED TOMOGRAPHY with resolution in the micrometer range.
The longest and largest bone of the skeleton, it is situated between the hip and the knee.
The prevention of access by infecting organisms to the locus of potential infection.
Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.
The hemispheric articular surface at the upper extremity of the thigh bone. (Stedman, 26th ed)
A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
General or unspecified injuries involving the hip.
Noninflammatory degenerative disease of the hip joint which usually appears in late middle or old age. It is characterized by growth or maturational disturbances in the femoral neck and head, as well as acetabular dysplasia. A dominant symptom is pain on weight-bearing or motion.
The seven bones which form the tarsus - namely, CALCANEUS; TALUS; cuboid, navicular, and the internal, middle, and external cuneiforms.
The growth action of bone tissue as it assimilates surgically implanted devices or prostheses to be used as either replacement parts (e.g., hip) or as anchors (e.g., endosseous dental implants).
The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices.
Products made by baking or firing nonmetallic minerals (clay and similar materials). In making dental restorations or parts of restorations the material is fused porcelain. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed & Boucher's Clinical Dental Terminology, 4th ed)
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
A condition with multiple tumor-like lesions caused either by congenital or developmental malformations of BLOOD VESSELS, or reactive vascular proliferations, such as in bacillary angiomatosis. Angiomatosis is considered non-neoplastic.
Chronic inflammation and granuloma formation around irritating foreign bodies.
Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and LEGG-CALVE-PERTHES DISEASE.
Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (GIANT CELLS, FOREIGN-BODY), usually surrounded by lymphocytes.
Tantalum. A rare metallic element, atomic number 73, atomic weight 180.948, symbol Ta. It is a noncorrosive and malleable metal that has been used for plates or disks to replace cranial defects, for wire sutures, and for making prosthetic devices. (Dorland, 28th ed)
Death of a bone or part of a bone, either atraumatic or posttraumatic.
A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
The presence of chyle in the thoracic cavity. (Dorland, 27th ed)
Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function.
The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.
A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principle cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX.
Replacement of the knee joint.
A bone on the ventral side of the shoulder girdle, which in humans is commonly called the collar bone.
Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.
The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.

The Gorham-Stout syndrome (Gorham's massive osteolysis). A report of six cases with histopathological findings. (1/39)

The Gorham-Stout Syndrome (Gorham's massive osteolysis) is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report six cases of the condition and present evidence that osteolysis is due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy such as with calcitonin or bisphosphonates may prevent local progressive osteolysis.  (+info)

Winchester syndrome. (2/39)

Winchester syndrome was first described in 1969 and since then nine patients have been reported in the literature. The syndrome is characterized by short stature, coarse face, corneal opacities, generalized osteolysis and progressive painful arthropathy with joint stiffness and contractures of distal phalanges in combination with skin changes. The etiology is unknown. Parental consanguinity supports autosomal inheritance. The diagnosis is based on clinical and radiological manifestations. We describe a case in a 7-year-old Pakistani boy.  (+info)

Mediastinal lymphangioma and chylothorax: thoracic involvement of Gorham's disease. (3/39)

We report a case of mediastinal lymphangioma associated with Gorham's disease in a 38-year-old man who had suffered recurrent clavicular fractures during a seven-year period. Mediastinal widening associated with osteolysis of the clavicles and the sternal manubrium was revealed by chest radiography, while computed tomography demonstrated a cystic anterior mediastinal mass infiltrating mediastinal fat and associated with osseous destruction of the clavicles and manubrium. Chylothorax recurred during the course of the disease.  (+info)

Wnt signalling during limb development. (4/39)

Wnts control a number of processes during limb development--from initiating outgrowth and controlling patterning, to regulating cell differentiation in a number of tissues. Interactions of Wnt signalling pathway components with those of other signalling pathways have revealed new mechanisms of modulating Wnt signalling, which may explain how different responses to Wnt signalling are elicited in different cells. Given the number of Wnts that are expressed in the limb and their ability to induce differential responses, the challenge will be to dissect precisely how Wnt signalling is regulated and how it controls limb development at a cellular level, together with the other signalling pathways, to produce the functional limb capable of coordinated precise movements.  (+info)

Chylothorax in Gorham's disease. (5/39)

A 25-yr-old woman presented with a right pleural effusion. Destruction of 9th through 12th ribs, adjacent vertebral bodies, and transverse processes was noted on plain radiograph and a large low-attenuated, irregular shaped mass lesion with peripheral rim enhancement, destroying vertebral body and transverse process, was revealed on the computed tomographic scan. Magnetic resonance imaging showed high signal on T1- weighted image and iso- and low signal on T2-weighted image for the mass lesion replacing the vertebral bony cortex and marrow space. An open rib biopsy revealed the histopathological changes of Gorham's disease (essential osteolysis), even though only bloody fluid filling the empty space and rib and vertebral transverse process destruction were grossly observed on operation. Even though there was no definite response to radiotherapy and pleurodesis, the patient showed stable condition up to 20 months after diagnosis.  (+info)

Primary idiopathic osteolysis: description of a family. (6/39)

A clinical, analytical, and radiological study was carried out on three members of the same family with multicentric idiopathic osteolysis. Transmission appeared to be via the dominant autosome present in the mother and two daughters. In the daughters osteolysis was seen in the carpal and tarsal bones, whereas in the mother radiology showed it to be in the phalanges of the hands and feet.  (+info)

Disappearing calvarium in Gorham disease: MR imaging characteristics with pathologic correlation. (7/39)

Gorham disease is a rare condition characterized by intraosseous neoplastic proliferation of hemangiomatous tissue with progressive, massive osteolysis. We present a pathologically proved case of Gorham disease that involved the left parietal bone in a 23-year-old man. Imaging studies including conventional radiography of the skull, CT, MR imaging, and Technetium-99 m (Tc-99 m) scintigraphy demonstrated a large skull defect without associated soft tissue mass over the left parietal skull. Contrast enhancement and increased isotope uptake along the margin of the defect were shown at gadolinium-enhanced T1-weighted MR imaging and Tc-99 m methylene diphosphate (Tc-99 m MDP) bone scintigraphy. Pathologic study revealed intraosseous angiomatosis at the periphery of the osteolytic skull lesion.  (+info)

Gorham disease of the spine: a case report and treatment strategies for this enigmatic bone disease. (8/39)

Gorham disease is an extremely rare condition of unknown etiology characterized by progressive osteolysis. Only 28 cases of its spinal involvement have been reported, and some of those cases showed kyphosis, kyphoscoliosis, subluxation or dislocation. No definite regimen of treatment has been established yet. A 10-year-old boy presented with a severe and progressive kyphosis over 90 degrees caused by Gorham disease from T3 to T12. In situ posterior fusion with a hook and rod system and iliac bone grafts were performed, but after surgery, he had complete paraplegia and its cause was uncertain. Based on the unfortunate consequence of the present case and the review of the literature, we propose the treatment strategies for spinal Gorham disease.  (+info)

Gorhams disease is a rare bone disorder that is characterized by bone loss (osteolysis), often associated with swelling or abnormal blood vessel growth (angiomatous proliferation). Bone loss can occur in just one bone, or spread to soft tissue and adjacent bones. It may affect any part of the skeleton, but most commonly involves the skull, shoulder, and pelvis. The cause of Gorhams disease is currently unknown. Most cases occur randomly. Treatment is based on the signs and symptoms present in each affected person, and most commonly involves surgery and/or radiation therapy. In some cases, Gorhams disease improves without treatment (spontaneous remission ...
Gorhams disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, is a very rare skeletal condition of unknown cause, characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis. Current treatments are experimental only. The symptoms of Gorhams disease vary depending on the bones involved. It may affect any part of the skeleton, but the most common sites of disease are the shoulder, skull, pelvic girdle, jaw, ribs, and spine. In some cases there are no symptoms until a fracture occurs either spontaneously or following minor trauma, such as a fall. There may be an acute onset of localized pain and swelling. More commonly there is pain of no apparent cause that increases in frequency and intensity over time and may eventually be accompanied by weakness and noticeable deformity of the area. The rate of progression is ...
Gorhams (GOR-amz) disease is a very rare skeletal condition of uncertain etiology, characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.1, 2 Because of the loss of the affected bone, the condition has been referred to as disappearing bone disease, vanishing bone disease, and massive osteolysis. In medical terminology osteolysis means: bone (osteo) breaking down or destruction (lysis).. The first known report of the condition came in 1838 in an article titled A Boneless Arm in what was then The Boston Medical and Surgical Journal, now The New England Journal of Medicine.3 It is a brief but fascinating report chronicling the case of Mr. Brown who had, in 1819 at age 18 years, broken his right upper arm in an accident. The patient suffered two subsequent accidents, which fractured the arm twice more before the curative process had been completed. At ...
Gorhams disease is a rare and potentially fatal condition characterized by proliferation of lymph vessels and destruction of bone tissue. It is important to emphasize novel therapeutic targets.
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Also called disappearing bone disease. Extensive loss of calcium from a single bone so that it cannot be seen on x-ray. Any bone can be involved but the upper arm, shoulder, and jaw are most frequent. This type of selective decalcification is sometimes associated with the presence of an hemangioma, a knot of distended blood vessels. The synonyms for this condition include invisible bone disease, vanishing bone disease, phantom bone disease and massive osteolysis.
The recently formed Rare Lung Diseases Consortium (RLDC) is holding a planning meeting in July 2015 to prepare for a national summit of all patient advocate organizations and the specialists in pulmonary science and medicine anticipated for 2016.. The RLDC is a unique collaboration among patient organizations, clinical investigators and the National Institutes of Health working together to accelerate clinical research and improve madical care for people with rare lung diseases. As a member of the RLDC, Jack Kelly, LGDA President & Board Member, will represent the LGDA at the planning meeting. We expect to name a specialist who will be representing the foundation at the meeting as well.. ...
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TY - JOUR. T1 - Gorham-Stout Disease Resulting in Spinal Deformity Treated by Fusion Surgery Combined With Everolimus Therapy. T2 - A Case Report. AU - Toga, Akira. AU - Watanabe, Kota. AU - Suzuki, Satoshi. AU - Nori, Satoshi. AU - Tsuji, Osahiko. AU - Nagoshi, Narihito. AU - Okada, Eijiro. AU - Yagi, Mitsuru. AU - Fujita, Nobuyuki. AU - Nakamura, Masaya. AU - Matsumoto, Morio. N1 - Publisher Copyright: Copyright © 2021 by The Journal of Bone and Joint Surgery, Incorporated.. PY - 2021/3/3. Y1 - 2021/3/3. N2 - CASE: Gorham-Stout disease (GSD) is a rare disorder characterized by progressive localized osteolysis and lymphatic malformation. A 26-year-old woman with GSD presented to our hospital with a Cobb angle of 100° and a kyphosis angle of 88°. Everolimus therapy was initiated to control the disease prior to surgery. After halo-gravity traction for 4 weeks, we performed anterior and posterior spinal fusion. Postoperative computed tomography revealed satisfactory bone union and no ...
Start Over You searched for: Authors Coffin, John G. (John Gorham), 1769-1829 ✖Remove constraint Authors: Coffin, John G. (John Gorham), 1769-1829 Subjects Cryotherapy ✖Remove constraint Subjects: Cryotherapy ...
At Gorham Family and Cosmetic Dentistry, Dr. Pidhajecky offers an array of dental services including porcelain veneers, dental implants, bruxism, digital x-rays, sealants, teeth whitening, endodontics and more.
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Gorham-Stout disease (GSD) is characterized by progressive bone destruction and proliferation of lymphatic vessels. In 2016, Andrea Del Fattore, PhD, and Andrea Bartuli, MD, and their team at Bambino Gesù Childrens Hospital, in Rome, Italy, were awarded funds raised for a research study through the LGDAs and LMIs participation in the Million Dollar Bike Ride (MDBR). The goal of the research was to help better understand the mechanisms which lead to bone loss in GSD. The findings suggest that the massive bone loss and vessel proliferation seen in GSD may be the result of independent alterations by bone cells in cooperation with systemic factors.. To conduct this study, the researchers obtained bone and blood samples from patients with GSD and compared them to the same type samples from patients without GSD (control cells). Among the highlights of the study:. ...
The syndrome of acute spontaneous absorption of bone is a rather rare and poorly understood condition. It is often referred to under such descriptive titles as disappearing bone, acute spontaneous absorption of bone, phantom bone and idiopathic osteolysis of bone. In the cases reported to date, several common factors seem to occur repeatedly: The patient is usually a young adult in good general health; minor trauma, usually to the affected area, calls attention to the lesion; pain is not a striking symptom; there is no sex predilection. The course of the disease is variable. Cases have been reported where the ...
The weight is 80 grams. The bowl is a beautiful pierced scroll design. There is no monogram. The spoon is marked with the Gorham logo, Sterling Pat.
As the morning approaches, learn to set things up. Mark your own home as a purchase participant. Start off marking each item with the value you think youll be able to sell it intended for. Be realistic about these charges; if you think you possibly can make more on a bidding site, sell there instead-but in the event you really could not sell it online, dont expect a good exorbitant value in person! Accumulate tables as well as old bedsheets to display things on. Start out early the a . m . of by means of setting almost everything out where people can easily see these people, grab yourself any chair and a brimmed hat, and get ready to sell! The roll off of Best Dumpster Rental in Gorham, NY looks like a miniature dumpster that one could rent for your own personal as well as business work with. You can get these kind of dumpsters in call sizes which include some definitely big measurements that will competing the ones you have at your community dumpster. You may be thinking just exactly why they ...
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Learn about the signs and symptoms of Gorham-Stout disease, a rare bone disorder expertly treated at Boston Childrens Hospital.
Vanishing bone disease (Gorham-Stout syndrome) is a rare entity of unknown etiology, characterized by destruction of osseous matrix and proliferation of vascular structures, resulting in destruction and absorption of bone. Despite the extensive investigation of the pathogenetic mechanisms of the disease, its etiology hasnt been clarified and several theories exist. The syndrome can affect one or multiple bones of the patient, including the skull, the upper and lower extremities, the spine and pelvis. The clinical presentation of a patient suffering from vanishing bone disease includes, pain, functional impairment and swelling of the affected region, although asymptomatic cases have been reported, as well as cases in which the diagnosis was made after a pathologic fracture ...
Gondivkar SM, Gadbail AR. Gorham-Stout syndrome: A rare clinical entity and review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e41-e48.(Indexed in PUBMED) ...
The union has resisted many of the popular education initiatives of the day and remains adamantly opposed to charter schools. It does not support tinkering with seniority-based layoff policies, and it rejected a district effort to rewrite teacher transfer rules so that principals and other school leaders would have a greater say in who fills vacant positions. Its leaders have pushed for smaller class sizes and a more consistent teaching force.. If union-backed candidates Thearse Pecot, Richard Fuentes, and Mike Hutchinson are victorious on Nov. 6, the Oakland Education Association will have certain expectations of them, said Trish Gorham, the union president. We expect a settled contract, Gorham said. … We expect accountability. We expect real oversight.. Gorham said she had no problem with a group advancing its interests - the California Teachers Association, after all, is contributing to the unions PAC. Still, she said, she was troubled to see such a large donation from Rock, a ...
Gorham King Edward Sterling Silver Flatware Flatware Roast Carving Knife. Gorham King Edward Sterling Silver Flatware Flatware Roast Carving Knife Was Inspired By Thomas Chippendales Highly Detaailed Design, This Collection Will Bring Regal And Gracious Design To Your Table. The Back Of The Design Provides An Exquisite Shield For A Monogram. Gray Finished Handles Are In Beautiful Contrast To Bright-finish Bowls And Tine. Using The Demanding, Multi-step Process Needed To Afhieve Superb Detailing, Durabiliyy And Finish, This Genuine Silver Flatware Is Crafted With The Same Passion Because Workmanship That Has Spanned Three Centuries Of Gorham. Duue To Silvee Price Fluctuation, All Orders At Current Prices Are Subject To Acceptance At The Time Of Receipt Of The Order. Prices Subject To Change Without Notice. Pictures The 3 Piece Place Setting To Permit Viewing Of The Pattern ...
Thomas Bradshaw, son of John and Valerie Bradshaw. College planning to attend: Will serve a 2-year mission for my church in Fresno, California. Major: Undecided. Awards: Eagle Scout, Coachs Award for Cross Country 2013, Excellence in Geometry Advanced, Recognition for Excellence in Art, Excellence in Pre-Engineering, Excellence in Pre-Calculus Advanced, Excellence in AP Calculus, Excellence in Advanced Physics, Excellence in AP Literature (Book Award), Most Likely to Succeed Superlative. Activities: Cross Country, Indoor Track, Outdoor Track, Boy Scouts, Active in Church Activities, Robotics Team. Nicole Brunet, daughter of Mary and Michel Brunet. College planning to attend: University of Western Ontario. Major: Biology. Awards: Perfect Attendance 2010-2011, Excellence in Sports Medicine, All Academic Award for Girls Varsity Downhill Skiing, Varsity Letter for Girls Varsity Downhill Skiing, Standout Student Award in 2011 and 2012 at the Dance Studio of Maine. Activities: Lacrosse 2011, Ski Team ...
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The new chief executive of the National Blood Authority will be Martin Gorham, director of projects and corporate affairs at the NHS Executive, South Thames. Mr Gorham is experienced at turning round troubled organisations. He was chief executive of the London Ambulance Service for four years from 1992.
PROVIDENCE - Most of the two dozen or so Reservoir Triangle neighborhood residents in attendance bit their tongues when it came to the still-sensitive subject of Alvarez High School - formerly Adelaide High School - even though they were gathered in its cafeteria.
Centralia, WA (PRWEB) November 01, 2012 -- Calling all writers, November is National Novel Writing Month or Nanowrimo. Started in 1999, this writing phenomenon
It is part of the Gen lab regulations for CAP. We have a company check our annually. J Joyce Weems Pathology Manager Saint Josephs Hospital 5665 Peachtree Dunwoody Rd NE Atlanta, GA 30342 404-851-7376 - Phone 404-851-7831 - Fax -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of Kathy Gorham Sent: Friday, February 01, 2008 7:58 AM To: [email protected] Subject: [Histonet] scales Good Friday Morning everyone: I have a regulation question: Do we have to calibrate our scales in Histology? And how often? I often check it but never heard we needed a procedure for it until now. Kathy Gorham, H.T. Grande Ronde Hospital LaGrande, Or _______________________________________________ Histonet mailing list [email protected] http://lists.utsouthwestern.edu/mailman/listinfo/histonet Confidentiality Notice ** The information contained in this message may be privileged and is confidential ...
Claudia Gorham knows how to deliver all types of commodities in the global marketplace. She is one of the outstanding students in UNFs Transportation and Logistics Flagship Program benefiting from a recent software donation teaching students how commodities get from point A to point B, anywhere in the world.. Manhattan Associates Inc., an Atlanta-based software development business, made the in-kind donation to the Logistics Information Technology Solutions Lab in the Coggin College of Business. The gift, part of The Power of Transformation campaign, makes the UNF lab one of the best equipped of its kind in the country.. Gorham is keenly aware of the advantages the high-power lab provides students. It absolutely gives us a competitive advantage in getting jobs. Its a resume builder because it demonstrates that we have a functional working knowledge of major industry software. This is an advantage few other universities can match, she said.. An Israeli citizen who has lived in several South ...
Drive yourself up the Mt. Washington Auto Road, Americas first manmade attraction, or take a guided tour to the 6288 ft. summit. Ride the winter SnowCoach to treeline.
As of the census[5] of 2000, there were 3,776 people, 1,410 households, and 1,036 families residing in the town. The population density was 77.2 people per square mile (29.8/km²). There were 1,900 housing units at an average density of 38.9 per square mile (15.0/km²). The racial makeup of the town was 98.36% White, 0.37% African American, 0.05% Native American, 0.13% Asian, 0.03% Pacific Islander, 0.21% from other races, and 0.85% from two or more races. Hispanic or Latino of any race were 0.48% of the population. There were 1,410 households out of which 32.7% had children under the age of 18 living with them, 60.2% were married couples living together, 8.9% had a female householder with no husband present, and 26.5% were non-families. 19.9% of all households were made up of individuals and 9.4% had someone living alone who was 65 years of age or older. The average household size was 2.66 and the average family size was 3.05. In the town, the population was spread out with 26.3% under the age ...
Lynott/Gorham/Downey, recorded by Thin Lizzy in the album Johnny The Fox] At a point below zero Theres no place left to go Six hundred unknown heroes Were killed like sleeping buffalo Through the devils canyon Across the battlefield Death has no companion The spirit is forced to yield There goes the bandolero Through the hole in the wall Hes a coward but doesnt care though In fact, he doesnt care at all The general thats commanding Hes defending what he fears While the troops they are depending On reinforcements from the rear If God is in the heavens How can this happen here? In His name, they used the weapons For the massacre There is a point below zero Where the sun can see the land Six hundred unknown heroes Lay dead in the ...
Preschool should be a time of play, happiness, and learning for young children. But across the United States, preschool students are expelled at 3.5 times the rate of students in grades K-12. These expulsions disproportionately affect children of color, especially boys. Black children make up 18 percent of preschool enrollment but 48 percent of preschool children suspended more than once.. These early actions can have a long-term impact. Children who are suspended in preschool are 10 times more likely to drop out of high school, experience academic failure, or have a negative school attitude than children who were not suspended or expelled. EDC early childhood experts Bertha Gorham and Dawn Nixon believe that fostering a supportive, child-centered environment is key to preventing expulsions-and to raising children who are ready to succeed in school. Here, they offer four tips for making this happen.. 1. Consider the whole child. Most expulsions and suspensions happen when students have physical ...
Creative Management Staffing Services is a small staff augmentation and recruiting firm. Started in 2013 by veteran Craig Gorham, the company was created with the mission to support disabled veterans and other service veterans transitioning or retiring from the military. By providing variety of staffing services, Creative Management Staffing Services matches specifically skilled veteran and non-veteran workers with clients in a wide range of industries.. Craig first contacted his PTAC for assistance with navigating the government marketplace. With his mission of assisting veterans in finding employment, Craig felt that government agencies and prime contractors would good potential markets. After working with his PTAC counselor on basic registrations, Craig began to search for opportunities within his niche. As the business grew through relationships with prime contractors such as SAS Institute, Craig recognized that he was ready to pursue 8(a) certification. His counselors helped him prepare his ...
Creative Management Staffing Services is a small staff augmentation and recruiting firm. Started in 2013 by veteran Craig Gorham, the company was created with the mission to support disabled veterans and other service veterans transitioning or retiring from the military. By providing variety of staffing services, Creative Management Staffing Services matches specifically skilled veteran and non-veteran workers with clients in a wide range of industries.. Craig first contacted his PTAC for assistance with navigating the government marketplace. With his mission of assisting veterans in finding employment, Craig felt that government agencies and prime contractors would good potential markets. After working with his PTAC counselor on basic registrations, Craig began to search for opportunities within his niche. As the business grew through relationships with prime contractors such as SAS Institute, Craig recognized that he was ready to pursue 8(a) certification. His counselors helped him prepare his ...
Wheres the cameraman? Stacey Sawyer asked with a laugh as she walked into the kitchen of her friend Cathy Davis in Gorham last Wednesday.. Sawyer, who was one of several neighbors who joined Davis at her home to watch the airing of the Judge Judy Show, was joking about what a spectacle her friends appearance on the show had become.. She watched as Judge Judy awarded Davis $1,500 for the value of her pet chicken, Princess, and the pain and suffering of watching her die. The chicken cost Davis $1.60 as a week old chick.. The story unfolded last fall when Davis of Jackies Way alleged that two dogs owned by Phillip Csoros of nearby Black Brook Road attacked Princess. The case wound up in the TV court and the story was widely published and broadcast on radio.. Judge Judy Sheindlin, a retired real-life judge from New York, where she had a tough but fair reputation, heard the case. During the TV trial, Csoros got a taste of Sheindlins sharp tongue that is a part of her TV persona.. Youre a ...
Directed by Félix Enríquez Alcalá. With Piper Perabo, Christopher Gorham, Kari Matchett, Anne Dudek. Annie tries to reach out and protect a mother and son after the son uncovers a coded IRA message.
A review of & Other Stories Fjäderholmarna hand soap, H&Ms sister company, with scents for the beauty range created by Byredos Ben Gorham.
I get along better with dogs than people. I have two dogs of my own who love meeting new friends and enjoy doggy daycare! I have been working with ...
Lynnie A. Rudner, Jack T. Lin, Il-Kyoo Park, Justin M. M. Cates, Darci A. Dyer, Douglas M. Franz, Margaret A. French, Elizabeth M. Duncan, Hillary D. White and James D. Gorham ...
Gorham, E. & Sanger, J. E., 1964, Recent Research in the Fields of Hydrosphere, Atmosphere and Nuclear Geochemistry. Miyake, Y. & Koyama, T. (eds.). Tokyo: Maruzen Co., p. 1-12 12 p. (Recent Research in the Fields of Hydrosphere, Atmosphere and Nuclear Geochemistry).. Research output: Chapter in Book/Report/Conference proceeding › Chapter ...
The following Surnames are currently included in this project:. Gorman, OGorman, McGorman, MacGorman, Ogorman, Garmon, Garman, Goram, Gorham, Gorin, Gormally, Blue, MacGhilleghuirman. The Gorman DNA Project is open to all Gorman families, of all spelling variations, and from all locations. (If your surname is not included, please contact me.). The Gorman DNA Project was started to:. 1. Help genealogical researchers from common or related families work together to find their shared heritage.. 2. Identify how the participants families are connected, both genetically and through paper trails.. 3. Identify and confirm genetic Lineages of ancestral families.. 4. Ultimately catalog pedigrees and genetic connections of all of the known project families.. The Gorman DNA Project is a Y-chromosome project. We do not work with mitochondrial DNA (mtDNA) data. If you have taken (or are now ordering) a Y-DNA test (e.g., Family Tree DNAs Y-DNA67 test), and your paternal Y-DNA lineage is known or suspected ...
News from the Press Herald and Maine Sunday Telegram. Serves southern Maine from Portland, Cape Elizabeth, Gorham, Falmouth to Lewiston-Auburn.
This page provides relevant content and local businesses that can help with your search for information on Dry Eye Syndrome Treatment. You will find informative articles about Dry Eye Syndrome Treatment, including Dry Eye Syndrome Causes And Treatments. Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Gorham, ME that can help answer your questions about Dry Eye Syndrome Treatment.
This page provides useful content and local businesses that can help with your search for Cervical Spinal Stenosis Injury Specialists. You will find helpful, informative articles about Cervical Spinal Stenosis Injury Specialists, including Cervical Spinal Stenosis. You will also find local businesses that provide the products or services that you are looking for. Please scroll down to find the local resources in Gorham, ME that will answer all of your questions about Cervical Spinal Stenosis Injury Specialists.
Local resource for yoga for menopausal women in Gorham, ME. Includes detailed information on local businesses that give access to yoga classes for seniors, alternative menopause treatments, senior yoga classes as well as information on senior centers and content on yoga.
Gorham, New Hampshire Doctor Near me | Gorham Clinics and Medicine | Find New Hampshire Healthcare professionals and more through Doctor Near Me
Start Over You searched for: Authors Coffin, John G. (John Gorham), 1769-1829 ✖Remove constraint Authors: Coffin, John G. (John Gorham), 1769-1829 Copyright Public domain ✖Remove constraint Copyright: Public domain Subjects Baths -- utilization ✖Remove constraint Subjects: Baths -- utilization Subjects Cryotherapy ✖Remove constraint Subjects: Cryotherapy ...
Create the flawless smile of your dreams with cosmetic dentistry in Gorham, including teeth whitening and porcelain veneers, from Morgan-Hill Dental Care.
Blaming a recent surge in natural gas prices, Gorham Paper and Tissue announced Friday afternoon it will lay off between 20 and 50 employees, and run only one or two of the companys four paper machines.
Veterinary Practice. Serving Dog, Cat, Bird, and Exotic Animals in and around Gorham, Westbrook, Portland, Buxton, Standish, Windham, Scarborough - Maine.
New York and Massachusetts both claimed the area of Monroe County. After the Revolution, the two states settled by allowing New York to have the right to govern, while Massachusetts had the right of pre-emption or first right to sell the land. Massachusetts sold those rights to Oliver Phelps and Nathaniel Gorham. Most of these rights later went to Robert Morris. Morris sold most of his rights to the Holland Land Company. The purchasers were also to acquire rights to the land from the Indians. For additional information, see Phelps and Gorham Purchase and My New York Genealogy, Monroe County. Land Records The Monroe County Clerk, as county registrar, has land records since 1821 when the county was created. The Clerk preserves and indexes the records. These records are housed at the Monroe County Court House at 39 W. Main Street, Rochester NY 14614. An online index, 1973 to the present plus images, 1976 to the present is available online. Registration is required to use this free database. Land ...
Gougeon S, Kemp KM, Blicher ME & Yesson C (2017) Mapping and classifying the seabed of the West Greenland continental shelf. Estuarine and Coastal Shelf Science. (doi:10.1016/j.ecss.2017.01.009). Yesson C, Fisher J, Gorham T, Turner CJ, Hammeken Arboe N, Blicher ME & Kemp KM (2016) The impact of trawling on the epibenthic megafauna of the West Greenland shelf. ICES Journal of Marine Science. (doi:10.1093/icesjms/fsw206). Williamson CJ, Yesson C, Briscoe A, Brodie J (2016) Complete mitochondrial genome of the geniculate calcified red alga, Corallina officinalis (Corallinales, Rhodophyta). Mitochondrial DNA Part B: Resources. (doi:10.1080/23802359.2016.1172048). Yesson C, Bedford F, Rogers AD, Taylor ML (2015) The global distribution of deep-water Antipatharia habitat. Deep Sea Research II. (doi:10.1016/j.dsr2.2015.12.004). Yesson C, Simon P, Chemshirova I, Gorham T, Turner CJ, Hammeken Arboe N, Blicher ME, Kemp KM (2015) Community composition of epibenthic megafauna on the West Greenland Shelf. ...
Newman contended that the C. of E. had no real identity and no future. It was not beholden to Christ or Catholic doctrine or the universal Church (either the actual one centered in Rome or the one imagined by Anglo-Catholics), but to the nation, public opinion, and the Spirit of the Age. It could only move further and further away from its mimic Catholicism. For Anglo-Catholics to remain in the C. of E. could not alter this destiny, only slow it down for a time. Re-garding the Spirit of the Age, and with reference to the Privy Council decision, Newman exclaimed elo-quently: The giant ocean has sud-denly swelled and heaved, and ma-jestically yet masterfully snaps the cables of smaller craft...and strands them upon the beach.... One vessel alone can ride those waves; it is the boat of Peter, the ark of God ...
New York and Massachusetts both claimed the area of Monroe County. After the Revolution, the two states settled by allowing New York to have the right to govern, while Massachusetts had the right of pre-emption or first right to sell the land. Massachusetts sold those rights to Oliver Phelps and Nathaniel Gorham. Most of these rights later went to Robert Morris. Morris sold most of his rights to the Holland Land Company. The purchasers were also to acquire rights to the land from the Indians. For additional information, see Phelps and Gorham Purchase and My New York Genealogy, Monroe County. Land Records The Monroe County Clerk, as county registrar, has land records since 1821 when the county was created. The Clerk preserves and indexes the records. These records are housed at the Monroe County Court House at 39 W. Main Street, Rochester NY 14614. An online index, 1973 to the present plus images, 1976 to the present is available online. Registration is required to use this free database. Land ...
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DENVER - More than 1,000 Catholics and other pro-life demonstrators showed up outside the Colorado State Capitol for an April 15 protest of what some were calling the most anything-goes pro-abortion bill in history.. And the initiative paid off, as the Colorado Senate on April 16 killed the controversial bill that could have banned all pro-life laws in the state.. Lift up your hearts in gratitude to God, said Denver Archbishop Samuel Aquila in a post on Twitter. Blessings on everyone who prayed and contacted legislators! Stay involved!. The legislation had passed committee on a party-line vote. While the floor debate and vote were initially scheduled for April 15, they were delayed until the following day, after Democratic state Sen. John Kefalas of Fort Collins went home sick. The Democrats control the Senate in the state by a single vote.. The far-reaching, long-term effects of this bill could be devastating to the pro-life cause, said Marie Gorham, who attended the protest that was ...
Tamamis, P.; Floudas, C. A. Elucidating a Key Anti-HIV-1 and Cancer-Associated Axis: The Structure of CCL5 (Rantes) in Complex with CCR5. Scientific Reports 2014, 4, 5447.. Tamamis, P.; Floudas, C. A. Elucidating a Key Component of Cancer Metastasis: CXCL12 (SDF-1α) Binding to CXCR4. Journal of Chemical Information and Modeling 2014, 54 (4), 1174-1188.. Tamamis, P.; Floudas, C. A. Molecular Recognition of CCR5 by an HIV-1 gp120 V3 Loop. PLoS ONE 2014, 9 (4), e95767.. Tamamis, P.; Terzaki, K.; Kassinopoulos, M.; Mastrogiannis, L.; Mossou, E.; Forsyth, V. T., Mitchell, E. P.; Mitraki, A. ; Archontis, G. Self-Assembly of an Aspartate-Rich Sequence from the Adenovirus Fibre Shaft: Insights from Molecular Dynamics Simulations and Experiments. Journal of Physical Chemistry B 2014, 118 (7),1765-1774.. Gorham Jr., R. D.; Forest, D. L; Tamamis, P.; Victoria, A. L. d; Kraszni, M.; Kieslich, C. A; Banna, C. D; Bellows-Peterson, M. L; Larive, C. K; Floudas, C. A; Archontis, G.; Johnson, L. V; Morikis, D. ...
Craig McDean In celebration of Craig McDeans latest photographic monograph - McDean Manual - close friends and collaborators, McDean and Ben Gorham, have devised a series of products and special editions of the book to be made available in Byredo stores
Ocean Beachs Tech Pet Care goes dog-sitters one better - Just ask the customer whose dog needed an injection and was looking for some sound professional advice: as long as what shes doing is within state guidelines Jan Gorham can wield a needle ...
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Today in 1987, peace activist George Ostensen enters the Extremely Low Frequency, or ELF Communication System Transmitter site near Clam Lake, Wisconsin.. He cuts down three ELF poles and pours blood over them. He also places photos of children inside groundswell electrical control boxes and plants flowers in them. Undetected, he goes to the Terminal Control Center to inform security guards of his actions.. He will be convicted of two counts of felony sabotage at his trial in Ashland and sentenced to thirty three months in prison.. Its This Weekends Action Calendar! Tonight, join local author Eric S. Piotrowski as he launches his book, This Aint What You Rung For, with a public reading. This is at 6 pm at Room of Ones Own Bookstore, 315 West Gorham. More details at just-text.org or call 241-2473.. Saturday, the Madison Infoshop and Madison Worker Cooperatives host a free screening of Shift Change, a 2012 documentary about worker cooperatives. There will be a potluck beginning at 6pm and ...
Sarah Gorham and Stone Morris, www.grinddining.com, talk about their lives, careers and experience of family caregiving. | Bringing the Joy of Eating Back for Alzheimers Disease Tuesday, December 2, 2014 on Family Caregivers Unite! | VoiceAmerica - The Leader in Internet Media
Ocean Beachs Tech Pet Care goes the dog-sitters one better - Just ask the customer whose dog needed an injection and was looking for some sound professional advice: as long as what shes doing is within state guidelines Jan Gorham can wield a nee...
Revision TKA with structural bulk allografting is associated with an up to 20% complication rate, usually related directly or indirectly to the allograft itself.10 For this reason endoprostheses are favoured by some authors.. Osteo-articular allografts. Historically in the 1970s there was a surge of interest in the use of bulk osteo-articular allografts. The benefit of osteo-articular grafting is joint preservation and soft tissue reattachment. However high complication rates were reported, particularly infection, fracture, non-union, graft dissolution and joint instability.11,12 Donor grafts need to be carefully matched to the recipient articular surface.The articular cartilage undergoes preservation in dimethyl sulfoxide and is stored at -80°C which results in very few of the chondrocytes remaining viable. This technique is seldom utilised today because of medium- and long-term failure. Hornicek et al reported that 25% of osteo-chondral allografts required surgical intervention due to ...
Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Yano K, Morinaga T, Higashio K (1999). "RANK is the essential signaling ... cause familial expansile osteolysis" (PDF). Nat. Genet. 24 (1): 45-8. doi:10.1038/71667. PMID 10615125. S2CID 32165581. Wong BR ... "RANK is essential for osteoclast and lymph node development". Genes Dev. 13 (18): 2412-24. doi:10.1101/gad.13.18.2412. PMC ... "Genetic linkage of familial expansile osteolysis to chromosome 18q". Hum. Mol. Genet. 3 (2): 359-61. doi:10.1093/hmg/3.2.359. ...
... acro-osteolysis MeSH C05.116.264.579.052.400 - Hajdu-Cheney syndrome MeSH C05.116.264.579.704 - osteolysis, essential MeSH ... osteolysis, essential MeSH C05.116.099.742 - platybasia MeSH C05.116.099.750 - Proteus syndrome MeSH C05.116.132.082 - ... MeSH C05.116.070.265 - bone cysts, aneurysmal MeSH C05.116.099.052 - acro-osteolysis MeSH C05.116.099.052.400 - Hajdu-Cheney ...
This process is essential for tumor progression, because as tumors grow they need increasing supplies of oxygen and nutrients. ... multicentric osteolysis, arthritis syndrome, and possibly keloids. Activity of MMP-2 relative to the other gelatinase (MMP-9) ... Degradation of the basement membrane is an essential step for the metastatic progression of most cancers. Cancer cell invasion ... Clark ES, Whigham AS, Yarbrough WG, Weaver AM (May 2007). "Cortactin is an essential regulator of matrix metalloproteinase ...
The sutures are an essential part of growth and development, allowing the skull to expand as the brain increases in size. ... Ross, Jane L.; Schinella, Roger; Shenkman, Louis (1978). "Massive osteolysis". The American Journal of Medicine. 65 (2): 367- ... Other structures of the human crown include blood vessels and nerves, which are essential for the allocation of nutrients to ... The cartilage evident within the cranium were an essential part in defending the central nervous system, however, over time the ...
Tiludronate has been used primarily for the treatment of diseases in horses that are associated with inappropriate osteolysis, ... Tripathi KD (2013-09-30). Essentials of medical pharmacology (Seventh ed.). New Delhi. ISBN 9789350259375. OCLC 868299888. ...
The most typical presentation is that of osteolysis of a single bone or the bones connected by a shared joint, such as the ... identification of the vascular or lymphatic proliferation within a generous section of the affected bone is an essential ... During this time period he also authored several case series on osteolysis of bone. Dr. Stout began his career as a surgeon and ... Heffez L, Doku HC, Carter BL, et al: Perspectives on massive osteolysis. Report of a case and review of the literature. Oral ...
essentials of skeletal radiology. Lippincott Williams & Wilkins. 2005. pp. 1-. GGKEY:29STUY0DQ70. Retrieved 21 June 2010. " ... preventing tumor-induced osteolysis. Indeed, in vitro studies have shown zoledronate to be effective in killing osteoclast-like ...
Food-induced purpura Generalized essential telangiectasia (general essential telangiectasia) Giant-cell arteritis Gougerot-Blum ... Hypotrichosis-acro-osteolysis-onychogryphosis-palmoplantar keratoderma-periodontitis syndrome Hypotrichosis-lymphedema- ... Biotin deficiency Carotenemia Essential fatty acid deficiency Folic acid deficiency Hypervitaminosis A Hypovitaminosis A ( ... Childhood granulomatous periorificial dermatitis Essential dermatitis Atopic dermatitis is a chronic dermatitis associated with ...
Over time, the cytoskeleton of the osteoclasts loses its function and the essential border[clarification needed] needed for ... oral antral communication or osteolysis extending from the inferior border of the mandible or the sinus floor. Surgical ...
Early detection and removal of the cysts is essential to reduce morbidity since dentigerous cyst can attain considerable size ... On CT imaging, a mandibular dentigerous cyst appears as a well-circumscribed unilocular area of osteolysis that incorporates ...
"Delayed peroneal nerve palsy after total knee arthroplasty-A rare complication of tibial osteolysis". The Knee. 21 (2): 624-7. ... numbness on leg when casted Precise knowledge about the length and exact localization of a damaged nerve segment is essential ...
Once the distal phalanx rotates, it is essential to derotate and re-establish its proper spatial orientation within the hoof ... and osteolysis of the coffin bone can occur. The chronic phase may be compensated or uncompensated. Compensated cases will have ...
2008). "BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday ... Other features include skeletal alterations (osteolysis, osteoporosis), amyotrophy (wasting of muscle), lipodystrophy and skin ... 2008). "RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability". Genes & Development. 22 ... associated with scleroderma-like lesions and acro-osteolysis: A case report and brief review of the literature". Pediatric ...
... essential; 145500; PNMT Hypertension, essential; 145500; AGTR1 Hypertension, essential; 145500; PTGIS Hyperthyroidism, familial ... FGFR1 Osteolysis, familial expansile; 174810; TNFRSF11A Osteopathia striata with cranial sclerosis; 300373; FAM123B ... essential; 187950; JAK2 Thrombocythemia, essential; 187950; MPL Thrombocythemia, essential; 187950; THPO Thrombocytopenia 4; ...
Cawson, RA (2008). Cawson's essentials of oral pathology and oral medicine. Edinburgh: Churchill Livingstone. p. 70. ISBN 978- ... osteolysis (bone resorption) and potentially abscess or cyst formation. The periodontal ligament becomes inflamed and there may ...
Other features include skeletal alterations (osteolysis, osteoporosis), amyotrophy (wasting of muscle), lipodystrophy and skin ... "RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability". Genes & Development. 22 (20): ... associated with scleroderma-like lesions and acro-osteolysis: A case report and brief review of the literature". Pediatric ... "BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction ...
... may be the principal means by which IL-17 causes arthritic osteolysis. In contrast to IL-17, IL-23, the essential inducer of ... Cytokine-induced focal osteolysis in RA. In many circumstances, osteolysis occurs adjacent to inflammation, such as in ... Pathogenesis of periprosthetic osteolysis. Periprosthetic osteolysis is the most significant long-term complication of total ... Inflammatory osteolysis: a conspiracy against bone. Gabriel Mbalaviele,1 Deborah V. Novack,1,2 Georg Schett,3 and Steven L. ...
Practice Essentials. Systemic mastocytosis, often termed systemic mast cell disease (SMCD), is a myeloproliferative neoplasm ... Osteolysis and pathological fractures (rare). See Presentation for more detail.. Diagnosis. Findings on blood studies may ... those with postthrombocythemic myeloid metaplasia was significantly higher than in those with polycythemia vera and essential ...
Phosphorylation of MafA is essential for its transcriptional and biological properties. Mol Cell Biol. 2001;21(14):4441-52. doi ... Why is the osteolysis in MCTO patients restricted to the carpal and tarsal bones? What makes these bones so special that they ... 1 Zankl A, Duncan EL, Leo PJ, Clark GR, Glazov EA, Addor MC, et al.Multicentric carpotarsal osteolysis is caused by mutations ... 3 Mumm S, Huskey M, Duan S, Wenkert D, Madson KL, Gottesman GS, et al.Multicentric carpotarsal osteolysis syndrome is caused by ...
Three-dimensional cellular development is essential for ex vivo formation of human bone. Nat Biotechnol 2000;18:954-8. ... Micro-CT showed that Bo-786 (Bo-786/Con) growth in bone induced osteolysis (Fig. 5B). In CBZ-treated mice (Bo-786/CBZ), ... Dual targeting c-met and VEGFR2 in osteoblasts suppresses growth and osteolysis of prostate cancer bone metastasis. Cancer Lett ... The bone microenvironment is crucial to the pathogenesis of osteolysis associated with renal cell carcinoma. A "vicious cycle" ...
A useful mnemonic when you see tapered osteolysis of the distal clavicle is: SHIRT Pocket Mnemonic S: scleroderma H: ... Essentials of Skeletal Radiology. (2005) ISBN:0781739462. Read it at Google Books - Find it at Amazon. ... Osteolysis of distal clavicle (mnemonic). Dr Henry Knipe ◉ ◈ and Dr Matt Skalski et al. ...
... exhibited preventative effects on titanium particle-induced osteolysis in a mouse calvarial model. Further histological ... and it might be a potential therapy for particle-induced osteolysis and other osteolytic diseases. ... exhibited preventative effects on titanium particle-induced osteolysis in a mouse calvarial model. Further histological ... and it might be a potential therapy for particle-induced osteolysis and other osteolytic diseases. ...
Yochum T, Rowe L. Essentials of Skeletal Radiology, 3rd ed. Baltimore: Williams & Wilkins, 2005. ... Posttraumatic Osteolysis of the Clavicle. By John M. Bassano, DC, DACBR. Patients commonly present to the chiropractic office ... The osteolysis can be identified on the radiographs within two to three months following the acute injury.1-3 When initiated by ... Distal osteolysis of the clavicle associated with trauma was first described in 1936.1,2 Initially believed to be a sequelae of ...
Plain radiographic examination is essential to narrow the range of possible diagnoses and to plan the next steps accordingly (2 ... The presence of weakened trabecular structures or osteolysis clearly points to osteitis. ...
Progressive osteolysis of the radius after distal biceps tendon repair with the bioabsorbable screw. J Shoulder Elbow Surg. ... Practice Essentials. The biceps brachii is the most powerful supinator of the forearm; along with the brachialis, it provides ...
Model-based cone-beam CT reconstruction for image-guided minimally invasive treatment of hip osteolysis Author(s): Yoshito ... To this purpose, a certain kind of understanding of the current situation in the OR is essential. Beyond that, anticipatory ... Conclusions: Application of KCR to imaging hip osteolysis in the presence of the implant offers a promising step toward ... Medical imaging is an essential component of a wide range of surgical procedures1. For image guided surgical (IGS) procedures, ...
Essential Osteolysis National Organization for Rare Disorders * Essential Thrombocythemia National Organization for Rare ... Essential Hemorrhagic Thrombocythemia National Organization for Rare Disorders * Essential Iris Atrophy National Organization ... Essential Tremor National Organization for Rare Disorders * Essiac/Flor Essence (PDQ®): Complementary and alternative medicine ... Essential Fructosuria National Organization for Rare Disorders * ...
IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of ... Rights & permissionsfor article IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL- ...
Familial essential tremor - See Essential tremor - not a rare disease * Familial expansile osteolysis - See Polyostotic ... Familial benign essential hematuria - See Thin basement membrane nephropathy - not a rare disease ... Familial X-linked 1 atypical mycobacteriosis - See NF-kappa B Essential Modulator Deficiency ...
Although the short-term results of PVP for LCH of the spine are promising, long-term follow-ups are essential for demonstrating ... Pain is explained by the onset of a collapse of the vertebral body with osteolysis. Neurological symptoms may be caused by the ... Histopathological confirmation is essential. The histopathological diagnostic criteria require the expression of CD1a and S-100 ...
Treating Hip and Pelvic Osteolysis *Managing Knee Osteolysis *Advances in Metals *Advances in Polyethylene *Improving UHMWPE ... Summarizes the essential engineering principles of joint replacements such as properties of biomaterials, wear and its sequelae ... Gene Therapy for Osteolysis *Pharmaceutical Treatment of Lysis *Genomics: The Promise for Orthopaedics Index. click here to see ... Wear Debris Induced Osteolysis *Role of Immune-Response in Implant Loosening *Stress-Induced Bone Remodeling *Pressure and ...
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res ... Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat Genet. 2000 Jan;24(1):45 ... located in the same region as do familial expansile osteolysis and a form of familial Paget disease of bone (10). RANK is a ...
Some patients may initially show extensive osteolysis before new bone formation. From 6 to 12 months after the start of therapy ... 2 Biopsy remains essential to confirm the diagnosis. ...
... and shape and have shown that such characteristics are essential to understand the causes of osteolysis. Research also ... WHAT IS OSTEOLYSIS? Osteolysis is a biological phenomenon that can result in the loosening of the implant, and it is ... has been shown to have a direct link to osteolysis and implant loosening. Osteolysis is an inflammatory biological response ... Mitigating Osteolysis in Clinical Total Hip Arthroplasty: The Role of Polyethylene Wear in Limiting the Life of Biomechanical ...
XGEVA is a fully human monoclonal antibody that binds to RANK Ligand (RANKL), a protein essential for the formation, function ... Signaling through the RANK receptor contributes to osteolysis and tumor growth. XGEVA prevents RANKL from activating its ...
MacPherson RL, Walker RD, Kowall MH (1973) Essential osteolysis with nephropathy. J Can Assoc Radiol 24: 98-103PubMedGoogle ... Abrahams J, Ganick D, Gilbert E, Wolfson J (1980) Massive osteolysis in an infant. AJR 135: 1084-1086PubMedGoogle Scholar ... Sage MR, Allen PW (1974) Massive osteolysis: report of a case. J Bone Joint [Br] 56: 130-134Google Scholar ... Johnson P, McClure J (1958) Observations on massive osteolysis. Radiology 71: 28-41PubMedGoogle Scholar ...
The cytokine osteopontin is essential for the dissemination of various cancers. Past research has implied several modes in ... but also to angiogenesis and osteolysis in bone metastases. Small molecule inhibitors of this receptor are under study as drug ...
... and osteolysis in severely affected joints (d). Original magnification ×200. (c) Original magnification ×100. (d) Articular ... Inducible costimulator is essential for collagen-induced arthritis. Roza I. Nurieva,1 Piper Treuting,2 Julie Duong,1 Richard A ... ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature. 2001. 409:97-102. View this article via: ... ICOS is essential for effective T-helper-cell responses. Nature. 2001. 2001:105-109. ...
Osteolysis is present in 70% of all cases, followed by osteopenia (10%), osteosclerosis (10%), and periosteal reactions (10%). ... Hand masses: An Essential MRI review By Nicholas Hardin, DO; Shaked Laks, MD; Carola Mullins, MD; Osvaldo Padilla, MD; Lisa ... Hardin N, Laks S, Smith C, Mullins C, Padilla O, Kafchinski L. Hand masses: An Essential MRI review . Appl Radiol. 2019;48(3): ...
Familial Expansile Osteolysis... joint pain *Familial Granulomatosis, Blau type... arthritis *Familial hypopituitarism... stiff ... Essential mixed cryoglobulinemia... joint pain , joint swelling*Facial dysmorphism -- intellectual deficit -- short stature -- ...
Eventually identified as periprosthetic osteolysis, this devastating disease affected over 1 million patients and was the ... It is an essential book not only for a medical library, but also for every library and bookstore." - Samuel J. Chmell, MD, ... William Harriss book on periprosthetic osteolysis is not only a must read for hip surgeons young and old, but will also be of ... "The purpose is to artfully recreate the evolution of the tackling of a medical problem, prosthetic osteolysis...This is a ...
This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been ... associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively ...
Nakagawa N, Kinosaki M, Yamaguchi K, Shima N, Yasuda H, Yano K, Morinaga T, Higashio K (1999). "RANK is the essential signaling ... cause familial expansile osteolysis" (PDF). Nat. Genet. 24 (1): 45-8. doi:10.1038/71667. PMID 10615125. S2CID 32165581. Wong BR ... "RANK is essential for osteoclast and lymph node development". Genes Dev. 13 (18): 2412-24. doi:10.1101/gad.13.18.2412. PMC ... "Genetic linkage of familial expansile osteolysis to chromosome 18q". Hum. Mol. Genet. 3 (2): 359-61. doi:10.1093/hmg/3.2.359. ...
... acro-osteolysis MeSH C05.116.264.579.052.400 - Hajdu-Cheney syndrome MeSH C05.116.264.579.704 - osteolysis, essential MeSH ... osteolysis, essential MeSH C05.116.099.742 - platybasia MeSH C05.116.099.750 - Proteus syndrome MeSH C05.116.132.082 - ... MeSH C05.116.070.265 - bone cysts, aneurysmal MeSH C05.116.099.052 - acro-osteolysis MeSH C05.116.099.052.400 - Hajdu-Cheney ...
Aseptic loosening and osteolysis around prosthetic joints are the principal causes of failure and consequent revision. During ... The pathophysiological factors of neurogenic or sympathetically mediated essential hypertension are unknown. Neurons close to ... Changes in pressure within the space around implants have been proposed as a cause of loosening and osteolysis. We ... ... Vascular compression of the rostral ventrolateral medulla in sympathetic mediated essential hypertension. ...
When osteolysis becomes severe, it can cause pain, loosening of the implant and the need for revision surgery to replace the ... so reviewing the current laboratory and clinical data for each of the new bearing surfaces is essential (read below). ... One way to relieve the problem of osteolysis and increase the longevity of joint replacements is to improve the wear resistance ... Clinical evidence is mounting that osteolysis and implant loosening in total hip patients with metal-on-metal bearings may be ...
  • Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. (genetex.com)
  • Defects in TNFRSF11A, which encodes a member of the TNF receptor family essential for RANKL-mediated osteoclastogenesis, cause familial expansile osteolysis. (thefreedictionary.com)
  • Defects in TNFRSF11A are the cause of familial expansile osteolysis (FEO) [MIM:174810]. (abcam.com)
  • Mutations cause autosomal recessive juvenile Paget disease, osteopetrosis, and dominant familial expansile osteolysis. (moldiag.com)
  • Aseptic loosening and periprosthetic osteolysis are the leading causes of total joint arthroplasty failure, which occurs as a result of chronic inflammatory response and enhanced osteoclast activity. (frontiersin.org)
  • Eventually identified as "periprosthetic osteolysis," this devastating disease affected over 1 million patients and was the leading cause of failure in total hip surgery. (oup.com)
  • Osteoclasts, the sole bone-resorbing cells, are multinucleated giant cells derived from hematopoietic monocyte-macrophage linage cells, and have a pivotal role in the pathogenesis of inflammatory bone disorders, such as rheumatoid arthritis, periodontal diseases, and periprosthetic osteolysis [ 1 , 2 ]. (mdpi.com)
  • In particular, RANKL acts as an essential modulator of osteoclast differentiation and activation by directly binding to its receptor, RANK, expressed on osteoclast precursors and mature osteoclasts [ 4 ]. (mdpi.com)
  • In bone metastatic lesions, osteoclasts play a key role in the development of osteolysis. (aacrjournals.org)
  • Over time, myeloma cells induce extensive osteolysis via the activation of bone resorbing osteoclasts [ 2 ]. (oncotarget.com)
  • The bone microenvironment is essential for the survival of myeloma cells, disease progression and drug resistance with many host cell types now known to play key roles including mesenchymal bone stromal cells (MSCs) and osteoclasts [ 4 , 5 ]. (oncotarget.com)
  • When inflammation occurs in the vicinity of bone, such as in RA, PsA, orthopedic implant-associated osteolysis, and osteomyelitis, it induces focal erosion that is often devastating. (jci.org)
  • Polyethylene wear debris, generated at the bearing surfaces of hip prostheses, has been shown to have a direct link to osteolysis and implant loosening. (kon.org)
  • Osteolysis eventually leads to the loosening of an implant and inevitably leads to the surgical removal of the implant. (kon.org)
  • This reaction, unfortunately, often leads to unwanted destruction of bone (called osteolysis ) around the implant. (hss.edu)
  • When osteolysis becomes severe, it can cause pain, loosening of the implant and the need for revision surgery to replace the implant components. (hss.edu)
  • Wear and consequent osteolysis are major causes of late failure in total hip arthroplasty, said Dr. Luigi Zagra, making proper bearing surface selection essential for implant survivorship and preservations of bone stock. (icjr.net)
  • Chronic infections can lead to osteolysis and implant loosening. (bvsalud.org)
  • Multicentric carpotarsal osteolysis (MCTO) is an autosomal dominant disease of the skeleton characterised by progressive destruction of carpal and tarsal bones. (smw.ch)
  • Multicentric carpotarsal osteolysis (MCTO, MIM 166300) is a rare disease of the skeleton characterised by aggressive destruction and disappearance of the carpal and tarsal bones, with other bones, including the metacarpals, being barely affected. (smw.ch)
  • RATIONALE: Multicentric carpotarsal osteolysis (MCTO) is a rare hereditary disease caused by mutations in MafB, a negative regulator of osteoclastogenesis. (bvsalud.org)
  • Torg JS, DiGeorge AM, Kirkpatrick JA Jr, Trujillo MM (1969) Hereditary multicentric osteolysis with recessive transmission: a new syndrome. (springer.com)
  • There are many causes of inflammatory osteolysis, but regardless of etiology and cellular contexts, the osteoclast is the bone-degrading cell. (jci.org)
  • Thus, the impact of inflammatory cytokines on osteoclast formation and function was among the most important discoveries advancing the treatment of focal osteolysis, leading to development of therapeutic agents that either directly block the bone-resorptive cell or do so indirectly via cytokine arrest. (jci.org)
  • Thus, insights into events such as those impacted by inflammasomes, which signal through cytokine-dependent and -independent mechanisms, are needed to optimize treatment of inflammatory osteolysis. (jci.org)
  • Further histological assessment and real-time PCR analysis indicated that stevioside prevented titanium particle-induced osteolysis by inhibiting osteoclast formation and inflammatory cytokine expression in vivo . (frontiersin.org)
  • Collectively, our data suggest that stevioside effectively suppresses osteoclastogenesis and inflammatory response both in vitro and in vivo , and it might be a potential therapy for particle-induced osteolysis and other osteolytic diseases. (frontiersin.org)
  • Osteolysis is an inflammatory biological response caused by macrophages that engulf wear debris formed in the peri-prosthetic tissue. (kon.org)
  • MRI can be useful in excluding an inflammatory arthropathy, and suggesting the diagnosis of carpal-tarsal osteolysis. (uea.ac.uk)
  • essential for RANKL-mediated osteoclastogenesis. (abcam.com)
  • 1-3 Posttraumatic osteolysis is not only seen in the distal clavicle, but also can occur at the medial clavicle, pubic symphysis and ischial rami, distal ulna and radius, carpal bones, distal phalanges, and the femoral neck. (dynamicchiropractic.com)
  • 1-3 If untreated, the osteolysis may extend up to 3 centimeters into the bony substance of the distal clavicle over a period of 12-18 months. (dynamicchiropractic.com)
  • The typical degree of osteolysis is approximately 1-3 millimeters into the bony substance of the distal clavicle within three months from the time of injury. (dynamicchiropractic.com)
  • Gorham L, Stout A (1955) Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone): its relation to hemangiomatosis. (springer.com)
  • Hejgaard N, Olsen PR (1987) Massive Gorham osteolysis of the right hemipelvis complicated by chylothorax: report of a case in a 9-year-old boy successfully treated by pleurodesis. (springer.com)
  • Gorham-Stout disease (GSD) or massive osteolysis, is an extremely rare osteolytic condition that involves extensive locally aggressive resorption of bone. (elsevier.com)
  • Devlin, RD, Bone, HG & Roodman, GD 1996, ' Interleukin-6: A potential mediator of the massive osteolysis in patients with Gorham-Stout disease ', Journal of Clinical Endocrinology and Metabolism , vol. 81, no. 5, pp. 1893-1897. (elsevier.com)
  • Massive cranial osteolysis, skin changes, growth retardation and developmental delay: Gorham syndrome with systemic manifestations? (elsevier.com)
  • Fingerprint Dive into the research topics of 'Massive cranial osteolysis, skin changes, growth retardation and developmental delay: Gorham syndrome with systemic manifestations? (elsevier.com)
  • CASE: Gorham-Stout disease (GSD) is a rare disorder characterized by progressive localized osteolysis and lymphatic malformation. (fujita-hu.ac.jp)
  • In 1954 Gorham and three others published a two case series, with a brief review of 16 similar cases from the medical literature, that advanced the hypothesis that angiomatosis was responsible for this unusual form of massive osteolysis. (lgdalliance.org)
  • 8 That same year Gorham and Stout presented to the American Association of Physicians their paper (in abstract form), "MASSIVE OSTEOLYSIS (ACUTE SPONTANEOUS ABSORPTION OF BONE, PHANTOM BONE, DISAPPEARING BONE): Its Relation to Hemangiomatosis. (lgdalliance.org)
  • Abrahams J, Ganick D, Gilbert E, Wolfson J (1980) Massive osteolysis in an infant. (springer.com)
  • Patrick JH (1984) Massive osteolysis complicated by chylothorax successfully treated by pleurodesis. (springer.com)
  • Johnson P, McClure J (1958) Observations on massive osteolysis. (springer.com)
  • Sage MR, Allen PW (1974) Massive osteolysis: report of a case. (springer.com)
  • Bullough P (1971) Massive osteolysis. (springer.com)
  • We report on a 16-month-old girl with multiple swellings on her skull due to massive osteolysis, growth retardation, facial anomalies, and wrinkly skin with mosaic hypopigmentation. (elsevier.com)
  • massive osteolysis. (lymphedemapeople.com)
  • 1, 2 Because of the loss of the affected bone, the condition has been referred to as disappearing bone disease, vanishing bone disease, and massive osteolysis. (lgdalliance.org)
  • The receptor activator of nuclear factor-κB (RANK)/RANK ligand pathway has emerged as the key pathway regulating osteolysis in skeletal metastasis. (biomedcentral.com)
  • Hardegger F, Simpson LA, Segmueller G (1985) The syndrome of idiopathic osteolysis. (springer.com)
  • These data indicate that ICOS is essential for collagen-induced arthritis and may suggest novel means for treating patients with rheumatoid arthritis. (jci.org)
  • The receptor integrin alpha(V)beta(3) contributes not only to tumor cell dissemination, but also to angiogenesis and osteolysis in bone metastases. (nih.gov)
  • It also buy 4382-63-2 contributes to problems of the buy 4382-63-2 disease including osteolysis and angiogenesis 8-10. (immune-source.com)
  • The sequelae were marked by the occurrence of an osteomyelitis with osteolysis of the entire upper right humerus extremity. (jocr.co.in)
  • Bone marrow analysis is essential to diagnosing multiple myeloma. (animalerspecialty.com)
  • Our data demonstrate that BMMPIs can decrease multiple myeloma burden and protect against cancer-induced osteolysis. (oncotarget.com)
  • The osteolysis can be identified on the radiographs within two to three months following the acute injury. (dynamicchiropractic.com)
  • areas of osteolysis are predominant in the acute phase, while sequester formation, predominance of sclerosis and periosteal reaction occur in chronic forms [3, 5]. (eurorad.org)
  • In this study, we investigated whether an inhibitor of M-CSF receptor (c-Fms) suppresses osteoclast-dependent osteolysis in bone metastatic lesions. (aacrjournals.org)
  • Direct osteolysis induced by metastatic murine melanoma cells role of matrix metalloproteinases. (forvps.ru)
  • A year later, after confirming by sequential radiographs that the osteolysis had stopped, total right hip replacement was performed. (bvsalud.org)
  • This receptor is also an essential mediator for osteoclast and lymph node development. (genetex.com)
  • In medical terminology osteolysis means: bone (osteo) breaking down or destruction (lysis). (lgdalliance.org)
  • To investigate the cause of the extensive resorption, we tested the effects of the patient's serum, sampled early in the course of treatment and later after the osteolysis was stabilized, on the formation of osteoclast-like multinucleated cells (MNC) in cultures of normal human marrow. (elsevier.com)
  • Longitudinal low dose µ CT analyses have been used to study treatments for enhancing the healing of calvarial defects in murine models [ 8 - 11 ] and to quantify tumor-induced osteolysis [ 12 ]. (hindawi.com)
  • 1,2 It may present as widening of the acromioclavicular joint, with either subtle erosion or complete osteolysis of the clavicle. (dynamicchiropractic.com)
  • However, much research remains to be done to completely understand the role of UHMWPE particles in osteolysis resulting from total hip arthroplasty. (kon.org)
  • Differences in the response to debris among patients, manifested by differences in the rapidity and extent of osteolysis around joint prostheses, are more probably related to factors other than the hypersensitivity response, such as the amount of particles released, individual differences in macrophage activation, or intracellular damage created by the particles after phagocytosis. (ovid.com)
  • Recognition of substances included in adhesion is definitely essential for understanding Millimeter biology and looking for book restorative focuses on for this disease. (immune-source.com)
  • These factors may ultimately influence the biological reaction and subsequent tendency for osteolysis. (hss.edu)
  • Carpal-tarsal osteolysis is a rare condition that manifests as the progressive resorption of carpal and tarsal bones in young children. (uea.ac.uk)
  • Production of titanium (Ti), ultra-high molecular weight polyethylene (UHMWPE), or cement wear debris following TJA is deemed to play a critical role in the process of osteolysis ( Noordin and Masri, 2012 ). (frontiersin.org)
  • Researchers have investigated several wear particle characteristics including particle size, volume, and shape and have shown that such characteristics are essential to understand the causes of osteolysis. (kon.org)
  • One way to relieve the problem of osteolysis and increase the longevity of joint replacements is to improve the wear resistance of the bearing materials. (hss.edu)
  • The most typical presentation is that of osteolysis of a single bone or the bones connected by a shared joint, such as the shoulder. (lgdalliance.org)
  • The cytokine osteopontin is essential for the dissemination of various cancers. (nih.gov)
  • Imaging findings are not specific, but are essential to evaluate local extent and to define treatment planning [1, 5]. (eurorad.org)
  • At the same time as some joints demonstrate osteolysis, others demonstrate total ankylosis. (bmj.com)