The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Solutions used to store organs and minimize tissue damage, particularly while awaiting implantation.
Total or partial excision of the larynx.
A trisaccharide occurring in Australian manna (from Eucalyptus spp, Myrtaceae) and in cottonseed meal.
Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.
Tumors or cancer of the HYPOPHARYNX.
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
Surgical removal of a part of the pharynx. (Dorland, 28th ed)
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
The process of protecting various samples of biological material.
The transference of a pancreas from one human or animal to another.
Preservation of cells, tissues, organs, or embryos by freezing. In histological preparations, cryopreservation or cryofixation is used to maintain the existing form, structure, and chemical composition of all the constituent elements of the specimens.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
A method of providing future reproductive opportunities before a medical treatment with known risk of loss of fertility. Typically reproductive organs or tissues (e.g., sperm, egg, embryos and ovarian or testicular tissues) are cryopreserved for future use before the medical treatment (e.g., chemotherapy, radiation) begins.
Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Treatment process involving the injection of fluid into an organ or tissue.
The transference of a part of or an entire liver from one human or animal to another.
Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host.
Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients.
An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
The total amount of radiation absorbed by tissues as a result of radiotherapy.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
The transference of a heart from one human or animal to another.
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
A therapeutic approach, involving chemotherapy, radiation therapy, or surgery, after initial regimens have failed to lead to improvement in a patient's condition. Salvage therapy is most often used for neoplastic diseases.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
The transference of a kidney from one human or animal to another.
An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
The administrative procedures involved with acquiring TISSUES or organs for TRANSPLANTATION through various programs, systems, or organizations. These procedures include obtaining consent from TISSUE DONORS and arranging for transportation of donated tissues and organs, after TISSUE HARVESTING, to HOSPITALS for processing and transplantation.
Transference of an organ between individuals of the same species or between individuals of different species.
A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
The process by which semen is kept viable outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
Procedures or techniques used to keep food from spoiling.
A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
The measurement of an organ in volume, mass, or heaviness.
Characteristic restricted to a particular organ of the body, such as a cell type, metabolic response or expression of a particular protein or antigen.
The spiral EPITHELIUM containing sensory AUDITORY HAIR CELLS and supporting cells in the cochlea. Organ of Corti, situated on the BASILAR MEMBRANE and overlaid by a gelatinous TECTORIAL MEMBRANE, converts sound-induced mechanical waves to neural impulses to the brain.
The chilling of a tissue or organ during decreased BLOOD perfusion or in the absence of blood supply. Cold ischemia time during ORGAN TRANSPLANTATION begins when the organ is cooled with a cold perfusion solution after ORGAN PROCUREMENT surgery, and ends after the tissue reaches physiological temperature during implantation procedures.
Method of tissue preparation in which the tissue specimen is frozen and then dehydrated at low temperature in a high vacuum. This method is also used for dehydrating pharmaceutical and food products.
Elements of limited time intervals, contributing to particular results or situations.
The process by which blood or its components are kept viable outside of the organism from which they are derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).

Beta-glucan reflects liver injury after preservation and transplantation in dogs. (1/524)

Graft failure and extrahepatic organ complications, which frequently develop after transplantation, may be related to inflammatory mediators stimulated by endotoxin (ET). The role of endotoxemia after liver transplantation is controversial and may depend upon differences in the ET assay method used in the various contradicting studies. While the standard Limulus amebocyte lysate (LAL) is reactive for ET and beta-glucan, a novel turbidimetric assay method enables separate determinations of ET and beta-glucan. Beagle dogs undergoing orthotopic liver transplantation were divided into two groups. In Group I (n = 6) the grafts were transplanted immediately and in Group II (n = 6) grafts were preserved for 48 h in University of Wisconsin (UW) solution. Animals received cyclosporine immunosuppression and were followed for 14 days. Daily measurements of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) were performed. Samples for ET and beta-glucan measurement were collected serially and processed using the turbidimetric assay method. While no graft failure was seen in Group I, three of six Group II animals died from graft failure within 1 day after transplantation. Preservation and reperfusion injury was much more severe in the Group II grafts than in Group I grafts. While endotoxemia could not be detected, postoperative beta-glucan levels (undetectable pretransplant) were seen in both groups. Beta-glucan levels were much higher in Group II grafts than in Group I grafts, and correlated with the severity of liver damage. In conclusion, this study shows that beta-glucan, instead of ET, appears during the early posttransplant period. We believe that posttransplant elevation of beta-glucan is related to liver damage, especially endothelial damage by preservation and reperfusion.  (+info)

Tissue donation after death in the accident and emergency department: an opportunity wasted? (2/524)

OBJECTIVE: To investigate whether the accident and emergency department (A&E) is a potential source of tissues for donation, from non-heart beating donors (NHBDs). METHODS: A telephone survey of 30 A&E departments was conducted to determine current tissue harvesting practices from NHBDs. The potential number of tissue donors in our own medium sized district general hospital A&E department was estimated. Senior nursing staff were asked to complete a questionnaire to establish their knowledge, attitudes, and experience of tissue harvesting from NHBDs. RESULTS: Only seven of the 30 A&E departments surveyed (23%) had an active involvement in requesting tissue donation after a sudden death. Several others had limited experience. The level of involvement was unrelated to department size. In our own A&E department, there were 110 deaths in 1995. Tissue donation had occurred on just three occasions. However, departmental staff attitudes towards reducing this shortfall were positive. CONCLUSIONS: The A&E department is a resource of tissues for donation, which is currently under used.  (+info)

Intravenous glycine improves survival in rat liver transplantation. (3/524)

In situ manipulation by touching, retracting, and moving liver lobes gently during harvest dramatically reduces survival after transplantation (P. Schemmer, R. Schoonhoven, J. A. Swenberg, H. Bunzendahl, and R. G. Thurman. Transplantation 65: 1015-1020, 1998). The development of harvest-dependent graft injury upon reperfusion can be prevented with GdCl3, a rare earth metal and Kupffer cell toxicant, but it cannot be used in clinical liver transplantation because of its potential toxicity. Thus the effect of glycine, which prevents activation of Kupffer cells, was assessed here. Minimal dissection of the liver for 12 min plus 13 min without manipulation had no effect on survival (100%). However, gentle manipulation decreased survival to 46% in the control group. Furthermore, serum transaminases and liver necrosis were elevated 4- to 12-fold 8 h after transplantation. After organ harvest, the rate of entry and exit of fluorescein dextran, a dye confined to the vascular space, was decreased about twofold, indicating disturbances in the hepatic microcirculation. Pimonidazole binding, which detects hypoxia, increased about twofold after organ manipulation, and Kupffer cells isolated from manipulated livers produced threefold more tumor necrosis factor-alpha after lipopolysaccharide than controls. Glycine given intravenously to the donor increased the serum glycine concentration about sevenfold and largely prevented the effect of gentle organ manipulation on all parameters studied. These data indicate for the first time that pretreatment of donors with intravenous glycine minimizes reperfusion injury due to organ manipulation during harvest and after liver transplantation.  (+info)

Organ transplantation--then and now. (4/524)

The last 25 years have seen amazing progress in transplantation--from the development of techniques for immunosuppression to methods for organ removal and preservation. Our distinguished authors focus on these developments and discuss how the momentum seen during the last quarter century can be accelerated.  (+info)

A study on continuous low-flow perfusion with low-potassium dextran for donor isolated lung preservation. (5/524)

OBJECTIVE: To test the validity of continuous low-flow perfusion with low-potassium dextran (LPD) to preserve rabbit lung. METHODS: Isolated rabbit lungs were preserved for eight hours either in Ringer's solution by simple storage (Group I) or in continuous low-flow perfusion with LPD (Group II). After preservation, lung functions were assessed to compare these two methods. RESULTS: The water gain in Group I was higher than that in Group II. During reperfusion, the functional test values for the immersed lungs were lower than those for the perfused lungs. The lipid peroxidation product (MDA) was significantly decreased in perfused lungs during reperfusion. CONCLUSIONS: Low-flow perfusion with LPD is better than immersion for the lung preservation.  (+info)

The effects of mannitol, albumin, and cardioplegia enhancers on 24-h rat heart preservation. (6/524)

During 24 h in vitro heart preservation and reperfusion, tissue damage occurs that seriously reduces cardiac function. Prevention of free radical production during preservation and reperfusion of ischemic tissue using free radical scavengers is of primary importance in maintaining optimal heart function in long-term preservation protocols. We examined whether mannitol (68 mM) and albumin (1.4 microM) in combination with other cardioplegia enhancers decreased free radical formation and edema and increased cardiac function during 24-h cold (5 degrees C) heart preservation and warm (37 degrees C) reperfusion in the Langendorff-isolated rat heart. The performance of mannitol-treated hearts was significantly decreased compared with that of hearts without mannitol treatment after 24 h of preservation with regard to recovery of diastolic pressure, contractility (+dP/dt), relaxation (-dP/dt), myocardial creatine kinase release, coronary flow, and lipid peroxidation. Albumin-treated hearts demonstrated higher cardiac function (contractility and coronary flow especially) than hearts not treated with albumin or hearts treated with mannitol, and this appears to be due to the positive effects of increased cellular metabolism and the enhancement of membrane stability.  (+info)

Endothelium-dependent relaxation of canine pulmonary artery endothelium after prolonged preservation. (7/524)

OBJECTIVE: Experiments were designed to investigate the effect of Euro-Collins (EC) solution and University of Wisconsin (UW) solution on function of pulmonary arterial endothelium. METHODS: Third order canine pulmonary artery segments were preserved in cold (4 degrees C) UW (group 1, n = 8) or EC (group 2, n = 9) solutions for 16 hours. The preserved (group 1 and 2) and control (group 3, n = 7) pulmonary arterial segments with and without endothelium were studied in vitro in organ chambers to measure isometric tension. RESULTS: The endothelium-dependent relaxation to acetylcholine and adenosine diphosphate of group 1 and 3 were significantly better than those of group 2. CONCLUSIONS: We concluded that endothelium-dependent relaxation of canine pulmonary arterial endothelium to receptor-dependent acetylcholine and adenosine diphosphate were impaired after preservation with Euro-Collins solution. However, endothelium-dependent relaxation of pulmonary segments were well maintained after preservation with University of Wisconsin solution.  (+info)

Controlling transplant vasculopathy in cryopreserved vein grafts with polyethylene glycol and glutathione during transport. (8/524)

BACKGROUND: the biological characteristics of cryopreserved allografts are poorly understood, although many factors are known to influence their outcome. This study examines the development of transplant vasculopathy in both fresh and cryopreserved vein allografts and specifically assesses the efficacy of a transport solution containing 10% polyethylene glycol and 10 microM glutathione (PEG/GSH). METHODS: jugular veins were harvested from control donor rabbits and transplanted as interposition carotid bypass grafts in 30 New Zealand White (NZW) rabbits. Ten received the fresh jugular veins (fresh). Ten animals received jugular veins which had been harvested, transported in a physiological solution, cryopreserved and stored in a standard fashion (cryopreserved). Ten animals received jugular veins which had been harvested, transported in the same solution with the addition of PEG/GSH, cryopreserved and stored in a standard fashion (PEG/GSH). Cryopreserved jugular veins were stored for 6 weeks before transplantation. All animals were sacrificed 28 days postoperatively. Vein grafts were perfusion-fixed and wall dimensions were determined by planimetry. RESULTS: all transplanted grafts were patent at harvest. The control cryopreserved vein grafts showed a 54% increase in mean intimal thickness (63+/-10 micron vs. 41+/-3 micron p<0.05) but no change in mean medial thickness (125+/-9 micron vs. 119+/-13 micron; p = N.S. ) compared to the fresh allograft. Transport of the grafts in PEG/GSH solution resulted in the abolition of the increase in intimal thickness (41+/-4 micron; p <0.01) associated with cryopreservation without a change in medial thickness (140+/-15 micron; p = N.S.) compared to the cryopreserved allograft. CONCLUSION: cryopreserved vein grafts develop significant intimal hyperplasia compared to freshly transplanted grafts. The use of PEG/GSH in the transport solution significantly reduces this transplant graft intimal hyperplasia to that which develops in fresh grafts and may lead to improvements in the clinical use of cryopreserved veins.  (+info)

The most common types of laryngeal neoplasms include:

1. Vocal cord nodules and polyps: These are benign growths that develop on the vocal cords due to overuse, misuse, or trauma.
2. Laryngeal papillomatosis: This is a condition where warts grow on the vocal cords, often caused by the human papillomavirus (HPV).
3. Adenoid cystic carcinoma: This is a rare type of cancer that develops in the salivary glands near the larynx.
4. Squamous cell carcinoma: This is the most common type of cancer that develops in the larynx, often due to smoking or heavy alcohol consumption.
5. Verrucous carcinoma: This is a rare type of cancer that develops on the vocal cords and is often associated with chronic inflammation.
6. Lymphoma: This is a type of cancer that affects the immune system, and can develop in the larynx.
7. Melanoma: This is a rare type of cancer that develops from pigment-producing cells called melanocytes.

Symptoms of laryngeal neoplasms can include hoarseness or difficulty speaking, breathing difficulties, and ear pain. Diagnosis is typically made through a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy. Treatment options vary depending on the type and severity of the neoplasm, but may include surgery, radiation therapy, or chemotherapy.

There are several types of hypopharyngeal neoplasms, including:

1. Squamous cell carcinoma (SCC): This is the most common type of hypopharyngeal cancer, accounting for about 90% of cases. It arises from the squamous cells that line the hypopharynx.
2. Adenocarcinoma: This type of cancer arises from the glandular cells that line the hypopharynx.
3. Other rare types: Other types of hypopharyngeal neoplasms include sarcomas, lymphomas, and melanomas.

The symptoms of hypopharyngeal neoplasms can vary depending on the location and size of the tumor. Common symptoms include:

1. Difficulty swallowing (dysphagia)
2. Pain when swallowing (odynophagia)
3. Hoarseness or voice changes
4. Lumps in the neck
5. Weight loss
6. Fatigue
7. Coughing up blood (hemoptysis)
8. Difficulty breathing (dyspnea)

Hypopharyngeal neoplasms are diagnosed through a combination of endoscopy, imaging tests such as CT scans or MRI, and biopsies. Treatment options include surgery, radiation therapy, chemotherapy, and targeted therapies. The prognosis for hypopharyngeal neoplasms depends on the stage and location of the tumor, as well as the patient's overall health.

In summary, hypopharyngeal neoplasms are a type of cancer that affects the lower part of the throat, and can be diagnosed through a combination of endoscopy, imaging tests, and biopsies. Treatment options include surgery, radiation therapy, chemotherapy, and targeted therapies, and the prognosis depends on the stage and location of the tumor, as well as the patient's overall health.

SCC typically appears as a firm, flat, or raised bump on the skin, and may be pink, red, or scaly. The cancer cells are usually well-differentiated, meaning they resemble normal squamous cells, but they can grow rapidly and invade surrounding tissues if left untreated.

SCC is more common in fair-skinned individuals and those who spend a lot of time in the sun, as UV radiation can damage the skin cells and increase the risk of cancer. The cancer can also spread to other parts of the body, such as lymph nodes or organs, and can be life-threatening if not treated promptly and effectively.

Treatment for SCC usually involves surgery to remove the cancerous tissue, and may also include radiation therapy or chemotherapy to kill any remaining cancer cells. Early detection and treatment are important to improve outcomes for patients with SCC.

The committee defined "brain death" as follows:

* The absence of any clinical or electrophysiological signs of consciousness, including the lack of response to pain, light, sound, or other stimuli.
* The absence of brainstem reflexes, such as pupillary reactivity, oculocephalic reflex, and gag reflex.
* The failure of all brain waves, including alpha, beta, theta, delta, and epsilon waves, as detected by electroencephalography (EEG).
* The absence of any other clinical or laboratory signs of life, such as heartbeat, breathing, or blood circulation.

The definition of brain death is important because it provides a clear and consistent criteria for determining death in medical settings. It helps to ensure that patients who are clinically dead are not inappropriately kept on life support, and that organ donation can be performed in a timely and ethical manner.

Some common types of head and neck neoplasms include:

1. Oral cavity cancer: Cancer that develops in the mouth, tongue, lips, or floor of the mouth.
2. Oropharyngeal cancer: Cancer that develops in the throat, including the base of the tongue, soft palate, and tonsils.
3. Hypopharyngeal cancer: Cancer that develops in the lower part of the throat, near the esophagus.
4. Laryngeal cancer: Cancer that develops in the voice box (larynx).
5. Paranasal sinus cancer: Cancer that develops in the air-filled cavities around the eyes and nose.
6. Salivary gland cancer: Cancer that develops in the salivary glands, which produce saliva to moisten food and keep the mouth lubricated.
7. Thyroid gland cancer: Cancer that develops in the butterfly-shaped gland in the neck that regulates metabolism and growth.

The risk factors for developing head and neck neoplasms include tobacco use, heavy alcohol consumption, human papillomavirus (HPV) infection, poor diet, and exposure to environmental carcinogens such as asbestos or radiation. Symptoms of head and neck neoplasms can vary depending on the location and size of the tumor, but may include a lump or swelling, pain, difficulty swallowing, bleeding, and changes in voice or breathing.

Diagnosis of head and neck neoplasms typically involves a combination of physical examination, imaging tests such as CT scans or MRI, and biopsy to confirm the presence of cancer cells. Treatment options can include surgery, radiation therapy, chemotherapy, targeted therapy, and immunotherapy, depending on the type, location, and stage of the cancer.

Overall, head and neck neoplasms can have a significant impact on quality of life, and early detection and treatment are important for improving outcomes. If you suspect any changes in your head or neck, it is essential to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

Reperfusion injury can cause inflammation, cell death, and impaired function in the affected tissue or organ. The severity of reperfusion injury can vary depending on the duration and severity of the initial ischemic event, as well as the promptness and effectiveness of treatment to restore blood flow.

Reperfusion injury can be a complicating factor in various medical conditions, including:

1. Myocardial infarction (heart attack): Reperfusion injury can occur when blood flow is restored to the heart muscle after a heart attack, leading to inflammation and cell death.
2. Stroke: Reperfusion injury can occur when blood flow is restored to the brain after an ischemic stroke, leading to inflammation and damage to brain tissue.
3. Organ transplantation: Reperfusion injury can occur when a transplanted organ is subjected to ischemia during harvesting or preservation, and then reperfused with blood.
4. Peripheral arterial disease: Reperfusion injury can occur when blood flow is restored to a previously occluded peripheral artery, leading to inflammation and damage to the affected tissue.

Treatment of reperfusion injury often involves medications to reduce inflammation and oxidative stress, as well as supportive care to manage symptoms and prevent further complications. In some cases, experimental therapies such as stem cell transplantation or gene therapy may be used to promote tissue repair and regeneration.

The definition of MOF varies depending on the context and the specific criteria used to define it. However, in general, MOF is characterized by:

1. The involvement of multiple organs: MOF affects multiple organs in the body, such as the lungs, liver, kidneys, heart, and brain. Each organ failure can have a significant impact on the individual's overall health and survival.
2. Severe dysfunction: The dysfunction of multiple organs is severe enough to cause significant impairment in the individual's physiological functions, such as breathing, circulation, and mental status.
3. Lack of specific etiology: MOF often occurs without a specific identifiable cause, although it can be triggered by various factors such as infections, injuries, or medical conditions.
4. High mortality rate: MOF is associated with a high mortality rate, especially if left untreated or if the underlying causes are not addressed promptly.

The diagnosis of MOF requires a comprehensive evaluation of the individual's medical history, physical examination, laboratory tests, and imaging studies. Treatment involves addressing the underlying causes, supporting the failing organs, and managing symptoms. The prognosis for MOF depends on the severity of the condition, the underlying cause, and the promptness and effectiveness of treatment.

Biostasis Organ transplant Southard JH, Belzer FO (1995). "Organ preservation". Annu Rev Med. 46 (1): 235-47. doi:10.1146/ ... University of Wisconsin cold storage solution remains what is often called the gold standard for organ preservation, despite ... UW solution was the first solution designed for use in organ transplantation, and became the first intracellular-like ... Developed in the late 1980s by Folkert Belzer and James Southard for pancreas preservation, the solution soon displaced ...
Speech organ • Squamous odontogenic tumor • Stafne defect • Stan Brown • Stanley D. Tylman • Stanley McInnis • Stannous ... Socket preservation • Sodium alginate • Soft palate • SoftDent • SOHP • Sonicare • Southern Regional Testing Agency • Sozodont ... Enamel organ • Enamel pearl • Enamel rod • Enamel spindles • Enamel tufts • Enamelin • Endodontic therapy • Endodontics • ...
"Hammond Organ Reed Factory, 9 May Street, Worcester". 2010 Preservation Award Winners. Massachusetts Historical Commission. " ... Reed Organ Society, Inc.; based on Gellerman, R.F. Gellerman's International Reed Organ Atlas (second ed.). HAMMOND, A.H., & CO ... as well as complete organs. Shown as Hammond Reed Co. in 1909. Hammond sold out to Hinners Organ Co. Foskett, Steven H., Jr. ( ... The former Hammond Organ Reed Factory is located southwest of downtown Worcester, at the southeastern corner of May and Silver ...
6. Hesse U.J., et al.: Organ preservation with HTK and UW solution. Pabst Sci. Publishers, D-49525 Lengerich, 1999. 7. Hatano E ... 4. Pokorny H., et al.: Histidine-tryptophan-ketoglutarate solution for organ preservation in human liver transplantation - a ... Specific Pokorny H; Rasoul-Rockenschaub S; Langer F (2004). "Histidine-tryptophan-ketoglutarate solution for organ preservation ... low-potassium preservation solution used for organ transplantation. The solution was initially developed by Hans-Jürgen ...
In addition, the organ's pipe chambers were effectively sealed off from the auditorium by the new shell - rendering the organ ... Cleveland Landmark Wins National Preservation Award. National Trust for Historic Preservation. 2001-10-01. Rosenberg, Donald. ... The stage included a place for the relocation of the Orchestra's newly-restored Ernest M. Skinner organ. The project also ... Finally, the 6,025-pipe Ernest M. Skinner organ could be heard, but its positioning outside the auditorium itself was ...
Southard JH (June 1989). "Viability assays in organ preservation". Cryobiology. 26 (3): 232-8. doi:10.1016/0011-2240(89)90017-5 ... For transplantable whole organs, the ultimate assay is the ability to sustain life after transplantation, an assay which is not ... A viability assay is an assay that is created to determine the ability of organs, cells or tissues to maintain or recover a ... Pegg, D. E. (1989-06-01). "Viability assays for preserved cells, tissues, and organs". Cryobiology. 26 (3): 212-231. doi: ...
"Frank Olsen, East Kilbride, Scotland, Wurlitzer". Scottish Theatre Organ Preservation Society. Retrieved 10 September 2022. " ... A Wurlitzer concert organ with two manuals and ten pipe ranks was installed in the hall. Following local government re- ...
"London, Granada Tooting - The Cinema Organ Society". Retrieved 4 September 2019. "Peterborough Theatre Organ Preservation ... The Cinema Organ Society has an extensive list of British cinema organs. Wurlitzer Theatre organ Friends of Beer Wurlitzer. " ... "The Cinema Organ Society". Cinema-organs.org.uk. Retrieved 14 October 2009. "Home". beerwurlitzer.org.uk. THE THEATRE ORGAN - ... This organ is now located at Rye College in East Sussex. The Trocadero Elephant and Castle Wurlitzer was the largest organ ever ...
ISBN 978-0-415-24700-9. Fahy, G.M.; Hirsh, A. (1982). Prospects for Organ Preservation by Vitrification. In: Organ Preservation ... and organ cryopreservation. In: Principles & Practice of Fertility Preservation (Donnez, J., and Kim, S.S., Eds.). Cambridge ... Before joining Twenty-First Century Medicine, he was the chief scientist for Organ, Inc and of LRT, Inc. He was also Head of ... Fahy GM, Wowk B, Wu J, Phan J, Rasch C, Chang A, Zendejas E (2004). "Cryopreservation of organs by vitrification: perspectives ...
... extensive preservation needs; and a main organ in disrepair. Repointing the building was estimated to cost at least $5 million ... The organ was to be replaced with a new instrument built by Dobson Pipe Organ Builders, but this plan was scrapped in 2009. As ... The Great Organ was installed by the Ernest M. Skinner & Son Organ Company in 1938. The original instrument consisted of ... "The Organ Project". Washington National Cathedral. Archived from the original on November 30, 2009. Retrieved December 16, 2018 ...
"The Statler Organ". The Theatre Organ Home Page. Retrieved May 18, 2020. Willig, Max (April 2011). "Slawinski at Assumption ... Buffalo Landmark & Preservation Board (May 3, 1980). "Building-Structure Inventory Form: Holy Cross Roman Catholic Church" (PDF ... "Schlicker Organ". Buffalo as an Architectural Museum. September 24, 2010. Retrieved June 10, 2020. McEneny, Daniel (April 14, ... Buffalo Landmark & Preservation Board (January 24, 1981). "Building-Structure Inventory Form: St. Nicholas Church" (PDF). New ...
The original Barton Organ is still used for special presentations. In 1964, the theatre underwent drastic modernization. Due to ... Recent preservation efforts have helped to restore the original splendor of the State. After years of uncertainty, Kalamazoo's ... Theatre organs were a unique combination of multiple instruments and sound effects. These intriguing machines greatly varied in ... The smaller palaces, such as the Kalamazoo State Theatre, would have had a chamber group or pipe organ. This was a great ...
"New 'supercooling' technology increases organ preservation time". The Times of India. 30 June 2014. Retrieved 30 June 2014. ... "Whole organ 'grown' in world first". BBC. 24 August 2014. Retrieved 25 August 2014. Agle, DC; Brown, Dwayne; Bauer, Markus (25 ... This breakthrough is a major step toward being able to grow whole organs from stem cells. 6 April - Samsung has developed a new ... related image) Experiments on rat livers have shown that a new cooling method can triple the time that donor organs can be ...
"National Organ Transplant Act" (PDF). 1984-10-19. Retrieved 2016-08-23. "United Network for Organ Sharing" (PDF). Retrieved ... The Methodist program implemented the first donor blood cryo-preservation allowing the rapid cross matching of pairs in a swap ... "United Network for Organ Sharing" (PDF). Retrieved 2016-08-26. Flechner, S. M.; Leeser, D.; Pelletier, R.; Morgievich, M.; ... "Organ Procurement and Transplantation Network and Scientific Registry of Transplant Recipients 2010 Data Report". American ...
Perdrizet, George (1989). "Stress conditioning: a novel approach to organ preservation". "Europe PMC". Vol. 46, no. 1. pp. 23-6 ... More recently, stress conditioning is being studied as a potential solution for the preservation of coral reefs as they are ... The science is clear that climate change will drive many species extinct, and a traditional, land-preservation ethic will not ... Increased resistance to warmer living conditions allow for the preservation of the Great Barrier Reef even as water ...
Five Foot Three is the RPSI's house organ. It is published annually On 7 November 2014, an RPSI train chartered by Web Summit ... The Railway Preservation Society of Ireland (RPSI) is an Irish railway preservation group operating throughout Ireland, founded ... "The Railway Preservation Society of Ireland". www.rpsi-online.org. Archived from the original on 10 February 2009. Retrieved 10 ... Irish Steam Preservation Society Irish Traction Group RPSI 2021s. Hewitt 2017. Newsroom 2019. Morton, Robin (Spring 1979). " ...
Perdrizet, George (1989). "Stress conditioning: a novel approach to organ preservation". "Europe PMC". Vol. 46, no. 1. pp. 23-6 ... More recently, stress conditioning is being studied as a potential solution for the preservation of coral reefs as they are ... Increased resistance to warmer living conditions allow for the preservation of the Great Barrier Reef even as water ...
"Holy Trinity Spring Lake - Organ". Retrieved 2010-05-23. Official website v t e v t e (Articles using NRISref without a ... Historic Preservation Office. March 1, 2011. p. 13. Archived from the original (PDF) on June 4, 2011. Retrieved April 26, 2011 ... The church houses a fully functional 1904 Bates & Culley pipe organ. "National Register Information System". National Register ...
2008). 'Metabolic Management - Organ Procurement and Preservation For Transplantation. New York: Landes Bioscience Springer. ... When it affects many cells in an organ, it causes some pallor, increased turgor, and increase in weight of the organ. On ... The body can make more cells to replace the damaged cells keeping the organ or tissue intact and fully functional. When a cell ... Stromal cells are the cells that support the parenchymal cells in any organ. Fibroblasts, immune cells, pericytes, and ...
New it is a provincial cultural relic preservation organ. The town is crossed by Provincial Highway S222. A Huaicong 2008, p. ...
The Organ Preservation Alliance[1] is also headquartered there; the Alliance is a nonprofit organization that works in ... "to catalyze breakthroughs on the remaining obstacles towards the long-term storage of organs" to overcome the drastic unmet ... medical need for viable organs for transplantation. Kleenspeed Technologies is headquartered there. On September 28, 2005, ... partnership with the Methuselah Foundation's New Organ Prize " ...
Artificial organs Anderson, Richard A.; Wallace, W. Hamish B.; Telfer, Evelyn E. (2017). "Ovarian tissue cryopreservation for ... An artificial ovary is a potential fertility preservation treatment that aims to mimic the function of the natural ovary. ... Cho, Eun; Kim, Yoon Young; Noh, Kevin; Ku, Seung-Yup (August 2019). "A new possibility in fertility preservation: The ... Conventional fertility preservation for females involves oocyte cryopreservation or ovarian tissue cryopreservation. However, ...
All of these add additional cost and logistical complexity to the organ retrieval, preservation and transplant process, but ... an organ or part of an organ in which the remaining organ can regenerate or take on the workload of the rest of the organ ( ... The National Organ Transplant Act of 1984 made organ sales illegal. In the United Kingdom, the Human Organ Transplants Act 1989 ... Artificial organ Beating heart cadaver Blood transfusion Laboratory-grown organ Organ donation Regenerative medicine Transplant ...
"Subzero organ preservation: the dawn of a new ice age?". Current Opinion in Organ Transplantation. 22 (3): 281-286. doi:10.1097 ... The freezers have attracted attention among organ banking and transplantation surgeons, as well as the food processing industry ... Szabó, Gábor (15 September 2012). "Hearts From the Deep Freezer? Novel Concept to Increase Safe Cardiac Preservation Times". ... "Supercooling enables long-term transplantation survival following 4 days of liver preservation". Nature Medicine. 20 (7): 790- ...
The fund donated $2 million to the Organ Preservation Alliance. The fund has also donated $1 million or more to organizations ... "The Pineapple Fund Donates Millions to the Organ Preservation Alliance and Methuselah Foundation". Fight Aging!. 2021-03-29. ...
The current organ and pulpit are preserved from this time. In the late nineteenth century, the church was rebuilt and the old ... The Digital Preservation Outreach and Education (DPOE), as part of the Library of Congress, serves to foster preservation of ... The preservation of born-digital content may include format transformations to facilitate long-term preservation or to provide ... Conway, Paul (2010). "Preservation in the Age of Google: Digitization, Digital Preservation, and Dilemmas" (PDF). The Library ...
"Trends in Total Laryngectomy in the Era of Organ Preservation". Otolaryngology-Head and Neck Surgery. 147 (1): 85-90. doi: ... Total laryngectomy results in the removal of the larynx, an organ essential for natural sound production. The loss of voice and ...
Development of multiple technical advances in organ preservation, procurement and transplant; Delineating the indications and ... Organ donation Xenotransplantation Immunosuppressive drugs Organ transplant Transplant rejection Cronin, Mike (2010-01-29). " ... Milestones in Organ Transplantation National Kidney Foundation Starzl TE, Klintmalm GB, Porter KA, Iwatsuki S, Schröter GP ( ... Starzl was a surgeon and researcher in the then nascent field of organ transplantation at the University of Colorado from 1962 ...
The organ of the organization was Nationaldemokraten (The National Democrat). When Swedish speakers from Finland arrived to ... The organization worked for preservation of monarchy and the official church. One year after founding, the organization had 75 ...
... particularly to renal transplant surgery and organ preservation, to accreditation and professional standards, as an academic, ... Kenneth Ralph Ames - For service to the preservation of rail transport history, and to youth. Jack Anastas - For service to the ... Pastor Perez De Lasala - For service to pipe organ restoration. Jaimie De Salis - For service to community health. Janeth ... Ian Trevor McIvor - For service to military history preservation, and to the community. Shirley Naina McIvor - For service to ...
This may have potentially important implications for organ transplant, as it could allow organs to survive for up to 18 hours ... C in an Arctic Hibernator Archived 2021-04-29 at the Wayback Machine Potential medical usage Harvested Human Lung Preservation ... Despite the inability to induce torpor, there are substances in the blood of hibernators that can lend protection to organs for ...
It is also possible that this organ functioned as a replacement for the parietal eye in Euchambersia, like the pit organ does ... although the prevalent sediments would not have been ideal for pollen preservation). In the Cistecephalus AZ, other co- ... hypothesized that the fossa may have supported a specialized sensory organ analogous to the pit organ of pit vipers and some ... Goris, R.C. (2011). "Infrared Organs of Snakes: An Integral Part of Vision". Journal of Herpetology. 45 (1): 2-14. doi:10.1670/ ...
Sternberg observed that being contained in the stomach of a mosasaur might have helped ensure the preservation of the ... 1904 Barnum Brown hypothesized that plesiosaurs used their gastroliths in a gizzard-like organ to grind up their invertebrate ... which had been muddled by the poor preservation of the fossils many early paleontologists had to rely on for their observations ...
The chimney was removed 1887 in order to install a pipe organ and to provide room for a sanctuary and a sacristy. Trinity ... Wood, Wayne W; Tool, Stephen Joseph; McEachin, Joel Wright; Davis, Judy; Vedas, David; Jacksonville Historic Preservation ...
ISBN 978-0-8129-3107-5. New York City Landmarks Preservation Commission; Dolkart, Andrew S.; Postal, Matthew A. (2009). Postal ... "Weekend Organ Meditations" on the Grace Church website Bowie, Walter Russell. Learning to Live, Abingdon Press, New York, 1969 ... all information in this table comes from New York City Landmarks Preservation Commission; Dolkart, Andrew S.; Postal, Matthew A ... and its rich musical program which includes regular organ recitals. Jonathan Mayhew Wainwright (third rector) - promoted ...
In recent years, the term is also used by the UN and its subsidiary organs. The Temple Mount forms the northern portion of a ... Preservation of the Holy Places Law, 1967. Jerusalem - The Legal and Political Background, Ministry of Foreign Affairs, ... its various organs and the Jewish organizations, which interfering with its extreme Jewish organizations, which attempt ... the Knesset passed the Preservation of the Holy Places Law, ensuring protection of the Holy Places against desecration, as well ...
"Burdett Organ Company - Pump Organ Restorations". www.pumporganrestorations.com. Retrieved 2022-03-30. LaPorte today: ... Illinois Historic Preservation Agency. Archived from the original (PDF) on November 20, 2015. Retrieved February 1, 2022. " ... the company was shipping 16 pianos and 30 organs a day. In 1907, Cable sold the Burdett Organ Co. to S.N. Swan & Sons, longtime ... may be increased from $100,000 to $200,000...." The company's organ business was managed by J.H. Brockmeier, who visited London ...
At a time when the NSW Builders' Labourers Federation led by Jack Mundey were becoming active in the preservation of Sydney's ... playing the organ at the temporary wooden pro-Cathedral, was a competent wood-carver and an amateur mechanical engineer". ...
Their meat was thought to have the ability to cure colds and prevent cancer and their organs were sold for medicinal purposes. ... Perry, Tony (July 4, 2012). "San Diego Zoo gets two Chinese alligators in preservation effort". Los Angeles Times. Archived ...
PLOSONE Issue 10: e1121, p.1-7. Richards, H.G., 1947, Preservation of fossil jellyfish: Bulletin of the Geological Society of ... Scyphozoans have no durable hard parts, including no head, no skeleton, and no specialized organs for respiration or excretion ...
Kratzing, Jean E. (1 February 1975). "The fine structure of the olfactory and vomeronasal organs of a lizard (Tiliqua ... like the Environment Protection and Biodiversity Conservation Act in 1999 have positively influenced the preservation of the ...
He accused social democrats of his time of acting to weaken "the national sentiment, the preservation of which [was his] ... near his heart without damaging any vital organ. Luckily, all his addresses were left on top of his things so that this worthy ...
Above it, there is the organ gallery. The original organ of 1844 had only five registers with an attached pedal. It was ... A great deal of the merit for the preservation of the building is due to Richard von Weizsäcker, at that time Mayor of West ... At the time of the general restoration of the interior in 1990, the parish could not afford a new organ. The new instrument was ... In order to complete the general view of the gallery, at present the organ space is held by a deceitfully real looking paper ...
Further foreshadowing the movie palace, the Riviera featured the organist Casimir Uszler who played an organ valued at $12,000 ... serve to fill commercial vacancies in Lincoln Village as well as promote historic preservation and to maintain the aesthetic ...
... and representative organ of the United Nations (UN). The building was designed by a group of architects led by Wallace Harrison ... since such a designation falls under the purview of the New York City Landmarks Preservation Commission. The General Assembly ...
Preservation Six of the inspection cars have been preserved, including No.3 on the CF Blonay-Camay and No. 6 on the CF ... ISBN 0-85361-536-5. Organ, John (2002). Northern France Narrow Gauge. Midhurst: Middleton Press. ISBN 1-901706-75-3. "Le Réseau ... Preservation Some twenty vehicles survive, including twelve on the Chemin de fer du Vivarais and four on the CF du Velay. 35 ... Preservation Some twenty vehicles have been preserved, mostly vans. They can be found on the CF Blanc-Argent, CFBS, ACFCdN and ...
At the time the Loew's Midland opened, it was home to a Robert Morton theatre pipe organ. The organ was used at the theatre ... According to the Cordish Company of Baltimore, the developer of the project, all changes meet historic preservation guidelines ... The organ began to deteriorate from lack of use until it was purchased and removed in the 1960s by Robert Fray and placed in ... After the organ changed hands and was moved across the country several more times, it was eventually purchased by local ...
... congas and organ. Possibly inspired by the character Polly Garter from Thomas's Under Milk Wood, the lyrics are a serenade for ... 1960s portal Rock music portal Preservation Act 1, 1973 concept album by the Kinks Preservation Act 2, 1974 concept album by ... "The Village Green Preservation Society [Super Deluxe Edition] - The Kinks". AllMusic. Archived from the original on 19 June ... The Kinks Are the Village Green Preservation Society is the sixth studio album by the English rock band the Kinks. Released on ...
Within these layers, the fish and other specimens are so highly preserved that their organs are often completely intact in ... Italy that was one of the first fossil sites with high quality preservation known to Europeans, and is still an important ... Exceptional Fossil Preservation. Columbia University Press. {{cite book}}: ,author= has generic name (help)CS1 maint: multiple ... and due to their popularity and preservation regularly sell for several hundred dollars. Monte Bolca is rich in fish: 250 ...
Cheese produced in Europe, where climates are cooler than in the Middle East, required less salt for preservation. With less ... Animal skins and inflated internal organs already provided storage vessels for a range of foodstuffs. Curdling milk in an ... For preservation purposes, cheese-making may have begun by the pressing and salting of curdled milk. ...
The finished church building measured 25 by 40 feet (7.6 m × 12.2 m). Inside the building were a pump organ in the front left ... Washington, DC: The Preservation Press. pp. 194-195. "The Lutheran Witness". The Lutheran Witness. March 1970. "The Southeast ... Washington, DC: The Preservation Press. Kamphoefner, Walter D. (1984). Chain Migration and Local Homogeneity of Immigration: ... Washington, DC: The Preservation Press. p. 172. Gulliford, Andrew (1984). America's Country Schools. ...
The organ was built by the Hinners Organ Company in 1930. It originally had electro-pneumatic action and was rebuilt in 1993 ... Historic Preservation Office. September 6, 2011. p. 2. Archived from the original (PDF) on July 5, 2010. Retrieved November 19 ... "OHS Database: Instrument 24919 Details". OHS Pipe Organ Database. 2015-10-13. Retrieved 2018-04-03. Wikimedia Commons has media ...
Other indicative and supportive biomarkers are useful in distinguishing DLB and AD (preservation of medial temporal lobe ... the nerves dealing with the unconscious functions of organs such as the intestines, heart, and urinary tract). The first signs ...
Noted for converting the "public use" requirement of the Takings Clause to "public purpose." Laidlaw v. Organ, 15 U.S. 178 ( ... "some reasonable relationship to the preservation or efficiency of a well regulated militia." District of Columbia v. Heller, ...
3 manual 11 rank theatre pipe organ, opus 1143, which was moved from the RKO Keiths Theatre in downtown Syracuse in 1966. This ... "Commissioner Ash Invites Visitors to State Park at the Fair". NYS Office of Parks, Recreation & Historic Preservation. August ... In 1967, the 1925 Mighty Wurlitzer Theatre Pipe Organ was permanently installed in the Empire Theatre of the Art & Home Center ... A total of 50 entertainment events ranging from major rock concerts to theater pipe organ concerts attracted 133,235 people. " ...
In order to fulfil the foundation's purpose, the foundation is divided into three organs: Management, Foundation Council and ... the focus of the foundation's work has been on the preservation of the building and its use for church services and as a venue ... board of trustees consists of six members who are appointed for five years and may not belong to any of the other organs of the ...
Prior to this removal, the organ was an integral feature of the popular midnight radio program "Nocturne" (detailed above). ... "Historical & Architectural Preservation / Historic Districts / Maps of Historic Districts / North Central", City of Baltimore, ... In the early 2000s, local engineer, theatre organ aficionado and player piano restoration technician, John R. Grant, attempted ... with Roland Nuttrell playing the Wurlitzer Organ and Charles Purcell reading poetry from 1937-1957. It closed in 1978 but is to ...
1912 Kotzschmar Memorial Organ installed in City Hall's Merrill Auditorium. Eastern Promenade laid out according to design by ... "Historic Preservation". City of Portland. Retrieved August 25, 2012. Published in the 19th century Nathaniel G. Jewett (1823). ... 1964 - Greater Portland Landmarks preservation group formed. 1965 - Kennedy Park housing built. 1967 - Summer weekend passenger ...
Organ Mountains-Desert Peaks National Monument, Protected areas established in 2019, 2019 establishments in New Mexico). ... designates the Wilderness as a component of the National Wilderness Preservation System, protecting approximately 27,673 acres ...
The preservation of a dead body was critical if the deceased wanted a chance at acceptance into the afterlife. Within the ... The first step was to remove the internal organs and liquid so that the body would not decay. After being laid out on a table, ... The oil was then drained out of the body, and with it came the internal organs, the stomach and the intestines, which were ... The next step was to remove the internal organs, the lungs, liver, stomach, and intestines, and to place them in canopic jars ...
Researchers have been trying for years to find ways to extend the shelf life of donor hearts and other organs in an effort ... boost the organ supply and save lives. In the lab study, researchers found that the former anti-seizure medication valproic ...
... and even whole organs thanks to a new computer model that predicts how tissues size will change during the preservation ... New computer model is a key step toward low-temperature preservation of 3D tissues, organs. Share:. ... New computer model is a key step toward low-temperature preservation of 3D tissues, organs ... and even whole organs thanks to a new computer model that predicts how tissues size will change during the preservation ...
FOPS Members LoginFOPS Members Organ InsuranceOrgan Owners GuidelinesFOPS Membership InformationFOPS Membership ProspectusFOPS ...
Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, ... The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create ... The promise of organ and tissue preservation to transform medicine Sebastian Giwa 1 2 3 , Jedediah K Lewis 1 , Luis Alvarez 4 5 ... An integrated approach to organ and tissue preservation would combine multiple preservation conditions and temperature ranges, ...
Organ, Tissue Transplant), by End Use, and Segment Forecasts, 2022-2030 ... Rising demand for transplant products such as tissue products, immunosuppressants, and organ preservation solutions is a major ... Shortage of organ donors. 3.4.2.2. Ethical and cultural issues. 3.4.3. Key opportunities prioritized. 3.4.3.1. Key ... 5.4.1. Organ transplant. 5.4.1.1. Market estimates and forecast, 2018-2030 (Revenue, USD Million). 5.4.2. Tissue transplant. ...
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This makes the Netherlands the first country worldwide to abandon static cold storage as standard preservation method for ... In use are two devices, the Kidney Assist-transporter from Organ Assist and the LifePort Kidney Transporter from Organ Recovery ... cold storage is still the default preservation method. ...
Organ Preservation Options Market: Segmental Overview. The organ preservation options market, by resolution, is segmented into ... posing a menace to the organ preservation resolution market.. Obtain Pattern PDF Brochure of Organ Preservation Options Market ... Organ Preservation Options Market: Key Insights. In response to our new analysis research on "Organ Preservation Options Market ... Rising Want for Organ Transplantation Drives Organ Preservation Options Market Development:. Rise in power illnesses that harm ...
Start Over You searched for: Subjects Organ Preservation ✖Remove constraint Subjects: Organ Preservation Publication Year 1600 ...
Pelvic organ prolapse and uterine preservation: a survey of female gynecologists (POP-UP s ... Pelvic organ prolapse and uterine preservation: a survey of female gynecologists (POP-UP survey). ... Discussing uterine cancer risk in relation to other organs had a less significant impact on their choices. CONCLUSIONS:. The ...
Wzo.org - an organization dedicated to the preservation of zebras * Home * Contact WE LOVE ZEBRAS. ...
Exceptional Preservation of organs and musculature is early vertebrates from the Gogo Formation Konservat-Lagerstätte., Hosted ... Plenary - Kate Trinajstic - Exceptional Preservation of organs and musculature is early vertebrates from the Gogo Formation ... Plenary - Kate Trinajstic - Exceptional Preservation of organs and musculature is early vertebrates from the Gogo Formation ... It has long been recognized for the diversity of the fauna and the exquisite 3D preservation of the fossils, but only recently ...
Organ Preservation in Patients with Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy. Journal of Clinical Oncology ... Organ Preservation in Patients with Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy. In: Journal of Clinical ... Organ Preservation in Patients with Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy. / Garcia-Aguilar, Julio; ... PURPOSEProspective data on the efficacy of a watch-and-wait strategy to achieve organ preservation in patients with locally ...
Summary: Bacterial contamination of organ preservation solution used in transplant surgery. Potentially contaminated products ... Infection Type: Multi-organ. Pathogen: Ebola Virus. When: October 2014. Where: Texas. Related Education/Training Materials: www ... Infection Type: Multi-organ. Pathogen: Multiple. When: January 2016. Where: New York. Related Education/Training Materials: www ... Fungal Infections in Organ Transplant Patients. Summary: An outbreak of mucormycosis infections in a cardiothoracic surgery ...
Rapid diagnosis is essential for organ preservation. Laboratory studies include the following:. * Complete blood cell count ( ...
Tissue preservation: Samples of total of 46 tissues and organs of all animals killed at scheduled necropsy and of the animal ... Organ weights:. At scheduled necropsy, the following organs were weighed (paired organs together) as soon as possible after ... Relative organ weights (g/kg body weight) were calculated from the absolute organ weights and the terminal body weight: ... specific target organ toxicity - single exposure (CLP Annex I No. 3.8.) - specific target organ toxicity - repeated exposure ( ...
A new preservation method protected human livers during cooling and kept them healthy for more than 24 hours. ... Fixing Flawed Body Parts: Engineering New Tissues and Organs. References: Supercooling extends preservation time of human ... Extending preservation time for donated livers. At a Glance. *A new preservation method protected human livers during cooling ... This mismatch is not only caused by a shortage of organ donors. It can also sometimes be hard to deliver a donated liver to the ...
We offer a full range of fertility preservation services for girls, like GnRH therapy, embryo and ovarian tissue freezing, and ... Surgical trauma / injury to adjacent organs. *Post-operative pelvic discomfort. *Some risk of toxic damage or metastasis to the ... This is the only available preservation option for pre-pubertal girls and is also available to post-pubertal women who cannot ... Fertility Consultation & Preservation Services offers a full spectrum of fertility services for male patients, including sperm ...
Organ preservation or orchiectomy?].. Kressel K; Schnell D; Dettmann R; Hartmann M; Butz M. Urologe A; 1993 May; 32(3):237-41. ...
Better organ preservation also means better outcomes for patients.. Transplant surgeries could become planned procedures ... In transplant, we still see a critical shortage of organs and people dying on the waitlist because there are not enough lungs ... The ability to extend the lifespan of the donor organ poses several advantages, says study first author Dr. Aadil Ali, adjunct ... Storing donor lungs for transplant at 10 degrees Celsius markedly increases the length of time the organ can live outside the ...
Organ Preservation; Organ Preservation Solutions; Tissue Donors; Ubiquinone/analogs & derivatives*; Ubiquinone/pharmacology ... RESULTS: A total of 13 donor corneal tissues with a mean (SEM) preservation time of 11.8 days (0.4) were included for the ...
... and methods for making organs more available (including organ storage and preservation); non-immune kidney allograft ... Other areas of interest include: dialytic therapy, organ procurement; ...
With tools from Silicon Valley, Quinton Smith builds lab-made organs By Erin Garcia de Jesús. May 30, 2023. ...
Additive solutions and cell/tissue/organ processing and preservation technologies. *Storage bags and/or new processes to ... Design principles that affect organ-specific transplantation biology and regenerative medicine. *Tools/algorithms for objective ...
An organ-sparing strategy could be an oncological equivalent alternative. Therefore, shared decision making between the patient ... Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy. J. Clin. Oncol. 2022, 40, ... An organ-sparing strategy could be an oncological equivalent alternative. Therefore, shared decision making between the patient ... Therefore, discussing treatment options, including organ-sparing strategies (watch-and-wait) as an oncological equivalent ...
Rectal Neoplasms, Organ Preservation Solutions, Organ Preservation, Endoscopy, Brachytherapy, Medical Oncology, ... Add to Calendar 24-04-2014 25-04-2014 2nd World Rectal Cancer Conference: the organ preservation challenge Leiden, Países ...
Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy. Garcia-Aguilar J, Patil S, ...
Kidney transplantation and organ preservation; Technology for diagnosis of kidney disease; Peritoneal dialysis; Inflammation of ... various organs Department of Urologic Sciences Faculty of Medicine Dubland Joshua Faculty (non-G+PS member) Clinical sciences; ...
... preservation of organ function. During the study, a 2-year-old ingested at one time an entire 35-day supply of hydroxyurea (612 ...
  • 1. Induction chemotherapy followed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II study. (nih.gov)
  • 4. Long-term Results of a Multicenter Randomized Phase III Trial of Induction Chemotherapy With Cisplatin, 5-fluorouracil, ± Docetaxel for Larynx Preservation. (nih.gov)
  • 6. [Induction chemotherapy and larynx preservation: is such practice useful? (nih.gov)
  • 8. Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. (nih.gov)
  • 1. Expression of p53 and Bcl-xL as predictive markers for larynx preservation in advanced laryngeal cancer. (nih.gov)
  • 12. Does induction chemotherapy still have a role in larynx preservation strategies? (nih.gov)
  • 16. Alteration of p53 pathway in squamous cell carcinoma of the head and neck: impact on treatment outcome in patients treated with larynx preservation intent. (nih.gov)
  • In 2011 she was awarded a QEII Fellowships from the ARC to continue work on soft tissue preservation within the Gogo fishes. (humanitix.com)
  • The Qiagen PAXgene non-formalin tissue preservation product was used to stabilize tissue specimens without cross-linking biomolecules. (ucsc.edu)
  • The internal organs, comprising eyes, heart, stomach, liver and guts has provided the first direct evidence that the earliest jawed vertebrates conformed to the extant vertebrate body bauplan (Trinajstic et al 2022). (humanitix.com)
  • Growing incidence of organ failure has resulted in massive growth in the transplantation market. (researchandmarkets.com)
  • Technological advancement in organ transplantation methods is another major factor supporting the market growth. (researchandmarkets.com)
  • Delivering viable organs to matching recipients within the window of viability can often be the most challenging aspect of organ transplantation," says Dr. Seila Selimovic, director of NIBIB's Engineered Tissues program. (nih.gov)
  • Dr. Rafika Bardi, head of the Tunisian Center for the Promotion of Organ Transplantation, said that "as in all the countries of the Maghreb. (arabnews.com)
  • The American Transplant Congress is designed for physicians, surgeons, scientists, nurses, organ procurement personnel and pharmacists who are interested in the clinical and research aspects of solid organ and tissue transplantation. (atcmeeting.org)
  • A variety of formats are planned that will encourage the exchange of new scientific and clinical information and support an interchange of opinions regarding care and management as well as socioeconomic, ethical, and regulatory issues relevant to organ and tissue transplantation. (atcmeeting.org)
  • RESULTS: A total of 13 donor corneal tissues with a mean (SEM) preservation time of 11.8 days (0.4) were included for the analysis. (nih.gov)
  • The Human Tissues and Organs Research Resource (HTORR) provides the biomedical research community with human tissues for research. (nih.gov)
  • It is a leading source of human tissues, cells and organs for scientific research and is comprised of a nationwide network of 130 tissue source sites over 45 states, including organ procurement organizations, tissue banks, post-surgery and post-mortem donors. (nih.gov)
  • Patients who underwent TME after restaging and patients who underwent TME after regrowth had similar DFS rates.CONCLUSIONOrgan preservation is achievable in half of the patients with rectal cancer treated with total neoadjuvant therapy, without an apparent detriment in survival, compared with historical controls treated with chemoradiotherapy, TME, and postoperative chemotherapy. (elsevierpure.com)
  • Medical science is a key step closer to the cryopreservation of brain slices used in neurological research, pancreatic cells for the treatment of diabetes and even whole organs thanks to a new computer model that predicts how tissue's size will change during the preservation process. (nih.gov)
  • Cryopreservation consists of preserving human individuals or organs at very low temperatures (less than -130°) in order to preserve them. (ewtn.com)
  • 7. Long-term results of a phase II trial of induction chemotherapy with uracil-ftegafur (UFT), vinorelbine, and cisplatin (UFTVP) followed by radiotherapy concomitant with UFT and carboplatin (RT/UFTJ) in a primary site preservation setting for resectable locally advanced squamous cell carcinoma of larynx and hypopharynx. (nih.gov)
  • 2. Expression of Bcl-2 family proteins in advanced laryngeal squamous cell carcinoma: correlation with response to chemotherapy and organ preservation. (nih.gov)
  • The process by which organs are kept viable outside of the organism from which they were removed (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism). (nih.gov)
  • 7. Overexpression of p53 predicts organ preservation using induction chemotherapy and radiation in patients with advanced laryngeal cancer. (nih.gov)
  • A cluster of mucormycosis infections in patients with hematologic malignancies, stem cell transplants, and solid organ transplants. (cdc.gov)
  • Prolonging the storage life of donated organs could eventually help increase the number of potential transplants. (nih.gov)
  • By giving doctors and patients more time, this research could someday affect thousands of patients who are waiting for liver or other organ transplants. (nih.gov)
  • Researchers have been trying for years to find ways to extend the shelf life of donor hearts and other organs in an effort boost the organ supply and save lives. (nih.gov)
  • Only in case of allocation of a donor kidney from the Netherlands to a center abroad, cold storage is still the default preservation method. (organpreservation.nl)
  • Depending on where a donor and recipient live, this may not be enough time to transport the organ and prepare for surgery. (nih.gov)
  • Campaigners in Algeria and Tunisia want to create registers of people who refuse to have their organs taken after their death - and anyone not on the list would be considered a potential donor by default. (arabnews.com)
  • This makes the Netherlands the first country worldwide to abandon static cold storage as standard preservation method for kidneys from these donors. (organpreservation.nl)
  • 10. Feasibility, toxicity, and efficacy of short induction chemotherapy of docetaxel plus cisplatin or carboplatin (TP) followed by concurrent chemoradio-therapy for organ preservation in advanced cancer of the hypopharynx, larynx, and base of tongue. (nih.gov)
  • 5. Predictive markers for response to chemotherapy, organ preservation, and survival in patients with advanced laryngeal carcinoma. (nih.gov)
  • 10. Organ preservation and treatment toxicity with induction chemotherapy followed by radiation therapy or chemoradiation for advanced laryngeal cancer. (nih.gov)
  • In use are two devices, the Kidney Assist-transporter from Organ Assist and the LifePort Kidney Transporter from Organ Recovery Systems. (organpreservation.nl)
  • Rising demand for transplant products such as tissue products, immunosuppressants, and organ preservation solutions is a major factor anticipated to boost the market's growth during the forecast period. (researchandmarkets.com)
  • From a religious point of view, there is nothing to oppose organ donation and the taking of organs from corpses," he said. (arabnews.com)
  • He and other Muslim theologians have argued that organ donation after death is "ongoing charity" - a pious act in Islam that outlives the person who performs it. (arabnews.com)
  • Organ donation. (arabnews.com)
  • She said the region lacked a "culture of donating organs" and that many people confuse organ donation with organ trafficking. (arabnews.com)
  • The study may also provide information about the effects of the test substance on neonatal morbidity, mortality, target organs in the offspring, and preliminary data on prenatal and postnatal developmental toxicity and serve as a guide for subsequent tests. (nih.gov)
  • Researchers led by Dr. Korkut Uygun of Harvard Medical School have been working on a system to extend the storage time of donated organs. (nih.gov)
  • First, the researchers removed all air from the storage system before preservation. (nih.gov)
  • Rapid diagnosis is essential for organ preservation. (medscape.com)
  • A new preservation method protected human livers during cooling and kept them healthy for more than 24 hours. (nih.gov)
  • With existing techniques, human organs can be preserved for an average of nine hours. (nih.gov)
  • Supercooling extends preservation time of human livers. (nih.gov)
  • Part of the problem lies with laws restricting the harvesting of human organs, coupled with cultural or religious reticence, despite Muslim theologians' approval of organ donations. (arabnews.com)
  • There are many fertility preservation options available to female patients who are planning to undergo potential ovary-damaging medical treatments. (cincinnatichildrens.org)
  • Many patients are critically ill as they wait for organs such as a heart which can only be taken from deceased donors. (arabnews.com)
  • 6. Tumor angiogenesis as a predictive marker for organ preservation in patients with advanced laryngeal carcinoma. (nih.gov)
  • The gift of an organ fulfils "one of the major objectives of Islamic law, which is the preservation of life," Chekkat said. (arabnews.com)
  • All tissue specimens were reviewed by pathologists to characterize and verify organ source. (ucsc.edu)
  • are among the many key firms working within the organ preservation options market. (transplant.news)
  • Below is a summary of options provided by the Comprehensive Fertility Care & Preservation Program. (cincinnatichildrens.org)
  • Pelvic organ prolapse and uterine preservation: a survey of female gynecologists (POP-UP survey). (bvsalud.org)
  • Thus, the availability of such advanced techniques supports an increase in the number of organ transplant procedures. (researchandmarkets.com)
  • But under Algerian law, a living person can donate an organ only to a parent, child, sibling or spouse. (arabnews.com)
  • But the law says organs may only be removed from a dead person if their family agrees. (arabnews.com)
  • is struggling to gain a foothold in Morocco, even though there are no prohibitions: not medical, legal or religious," Moroccan organ registrar Said Sabri told AFP. (arabnews.com)
  • Bacterial contamination of organ preservation solution used in transplant surgery. (cdc.gov)