Tumors or cancer of the MOUTH.
The aftermost permanent tooth on each side in the maxilla and mandible.
A plant genus of the family ARECACEAE. Members contain ARECOLINE and CATECHIN. The leaves and nuts have been used as masticatories, stimulants, and astringents in traditional medicine. The common name of betel is also used for PIPER BETLE. The common name of catechu is sometimes used for ACACIA CATECHU.
A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).
Methods to identify and characterize cancer in the early stages of disease and predict tumor behavior.
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Powdered or cut pieces of leaves of NICOTIANA TABACUM which are inhaled through the nose, chewed, or stored in cheek pouches. It includes any product of tobacco that is not smoked.
Tumors or cancer of the PHARYNX.
Tumors or cancer of the TONGUE.
Inhaling and exhaling the smoke of burning TOBACCO.
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
Ability of neoplasms to infiltrate and actively destroy surrounding tissue.
Tumors or cancer of the PROSTATE.
A white patch lesion found on a MUCOUS MEMBRANE that cannot be scraped off. Leukoplakia is generally considered a precancerous condition, however its appearance may also result from a variety of HEREDITARY DISEASES.
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
A cell line derived from cultured tumor cells.
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Tumors or cancer of the human BREAST.
Tumors or cancer of the LUNG.
Tumors or cancer of the STOMACH.
A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.
Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
Tumors or cancer of the COLON.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
Methods which attempt to express in replicable terms the extent of the neoplasm in the patient.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery.
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
The worsening of a disease over time. This concept is most often used for chronic and incurable diseases where the stage of the disease is an important determinant of therapy and prognosis.
A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Vaccines or candidate vaccines designed to prevent or treat cancer. Vaccines are produced using the patient's own whole tumor cells as the source of antigens, or using tumor-specific antigens, often recombinantly produced.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Tumors or cancer of the OROPHARYNX.
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Ending the TOBACCO habits of smoking, chewing, or snuff use.
The largest and strongest bone of the FACE constituting the lower jaw. It supports the lower teeth.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
Tumors or cancer of the UTERINE CERVIX.
In vivo methods of screening investigative anticancer drugs, biologic response modifiers or radiotherapies. Human tumor tissue or cells are transplanted into mice or rats followed by tumor treatment regimens. A variety of outcomes are monitored to assess antitumor effectiveness.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Predetermined sets of questions used to collect data - clinical data, social status, occupational group, etc. The term is often applied to a self-completed survey instrument.
A potent mutagen and carcinogen. This compound and its metabolite 4-HYDROXYAMINOQUINOLINE-1-OXIDE bind to nucleic acids. It inactivates bacteria but not bacteriophage.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
All of the processes involved in increasing CELL NUMBER including CELL DIVISION.
The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
DNA present in neoplastic tissue.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for "cancer." (From Dorland, 27th ed)
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
Tumors or cancer of the URINARY BLADDER.
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.
Component of the NATIONAL INSTITUTES OF HEALTH. Through basic and clinical biomedical research and training, it conducts and supports research with the objective of cancer prevention, early stage identification and elimination. This Institute was established in 1937.
The local recurrence of a neoplasm following treatment. It arises from microscopic cells of the original neoplasm that have escaped therapeutic intervention and later become clinically visible at the original site.
The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
Laws and regulations pertaining to the field of dentistry, proposed for enactment or recently enacted by a legislative body.
Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved.
Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions.
Experimental transplantation of neoplasms in laboratory animals for research purposes.
A subspecialty of internal medicine concerned with the study of neoplasms.
Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.
Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.
Educational programs designed to inform dentists of recent advances in their fields.
Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor.
The act and process of chewing and grinding food in the mouth.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
A tooth that is prevented from erupting by a physical barrier, usually other teeth. Impaction may also result from orientation of the tooth in an other than vertical position in the periodontal structures.
The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
Surgical procedures used to treat disease, injuries, and defects of the oral and maxillofacial region.
Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
The use of chemical compounds to prevent the development of a specific disease.
Education which increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of dental health on a personal or community basis.
Individuals licensed to practice DENTISTRY.
Nonspecialized dental practice which is concerned with providing primary and continuing dental care.
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Tumors or cancer of the RECTUM.
Cells grown in vitro from neoplastic tissue. If they can be established as a TUMOR CELL LINE, they can be propagated in cell culture indefinitely.
Processes required for CELL ENLARGEMENT and CELL PROLIFERATION.
The total amount (cell number, weight, size or volume) of tumor cells or tissue in the body.
Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
Patterns of practice in dentistry related to diagnosis and treatment.
A genus of RED ALGAE in the family Gracilariaceae. It is a highly commercial SEAWEED and a source of AGAR.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
The relationship between the dose of an administered drug and the response of the organism to the drug.
The complex series of phenomena, occurring between the end of one CELL DIVISION and the end of the next, by which cellular material is duplicated and then divided between two daughter cells. The cell cycle includes INTERPHASE, which includes G0 PHASE; G1 PHASE; S PHASE; and G2 PHASE, and CELL DIVISION PHASE.
The part of the face that is below the eye and to the side of the nose and mouth.
A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Regular course of eating and drinking adopted by a person or animal.
Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.
Tumors or cancer of ENDOMETRIUM, the mucous lining of the UTERUS. These neoplasms can be benign or malignant. Their classification and grading are based on the various cell types and the percent of undifferentiated cells.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
The fission of a CELL. It includes CYTOKINESIS, when the CYTOPLASM of a cell is divided, and CELL NUCLEUS DIVISION.
Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.
Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.
DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
Interruption or suppression of the expression of a gene at transcriptional or translational levels.
Immunologic techniques based on the use of: (1) enzyme-antibody conjugates; (2) enzyme-antigen conjugates; (3) antienzyme antibody followed by its homologous enzyme; or (4) enzyme-antienzyme complexes. These are used histologically for visualizing or labeling tissue specimens.
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Variant forms of the same gene, occupying the same locus on homologous CHROMOSOMES, and governing the variants in production of the same gene product.
A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.
A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329)
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Tumors or cancer of the ESOPHAGUS.
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.
The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
Transplantation between animals of different species.
The uptake of naked or purified DNA by CELLS, usually meaning the process as it occurs in eukaryotic cells. It is analogous to bacterial transformation (TRANSFORMATION, BACTERIAL) and both are routinely employed in GENE TRANSFER TECHNIQUES.
RNA present in neoplastic tissue.
Highly proliferative, self-renewing, and colony-forming stem cells which give rise to NEOPLASMS.
Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS.
The teeth collectively in the dental arch. Dentition ordinarily refers to the natural teeth in position in their alveoli. Dentition referring to the deciduous teeth is DENTITION, PRIMARY; to the permanent teeth, DENTITION, PERMANENT. (From Jablonski, Dictionary of Dentistry, 1992)
The part of a tooth from the neck to the apex, embedded in the alveolar process and covered with cementum. A root may be single or divided into several branches, usually identified by their relative position, e.g., lingual root or buccal root. Single-rooted teeth include mandibular first and second premolars and the maxillary second premolar teeth. The maxillary first premolar has two roots in most cases. Maxillary molars have three roots. (Jablonski, Dictionary of Dentistry, 1992, p690)
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.
Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
The loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal HEMIZYGOSITY. It is detected when heterozygous markers for a locus appear monomorphic because one of the ALLELES was deleted.
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human CHROMOSOME 17 at locus 17q21. Mutations of this gene are associated with the formation of HEREDITARY BREAST AND OVARIAN CANCER SYNDROME. It encodes a large nuclear protein that is a component of DNA repair pathways.
Radiographic examination of the breast.
Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
Proteins, glycoprotein, or lipoprotein moieties on surfaces of tumor cells that are usually identified by monoclonal antibodies. Many of these are of either embryonic or viral origin.
In humans, one of the paired regions in the anterior portion of the THORAX. The breasts consist of the MAMMARY GLANDS, the SKIN, the MUSCLES, the ADIPOSE TISSUE, and the CONNECTIVE TISSUES.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.
Dissection in the neck to remove all disease tissues including cervical LYMPH NODES and to leave an adequate margin of normal tissue. This type of surgery is usually used in tumors or cervical metastases in the head and neck. The prototype of neck dissection is the radical neck dissection described by Crile in 1906.
The inspection of one's own body, usually for signs of disease (e.g., BREAST SELF-EXAMINATION, testicular self-examination).
Neoplasms of the skin and mucous membranes caused by papillomaviruses. They are usually benign but some have a high risk for malignant progression.
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
A cancer registry mandated under the National Cancer Act of 1971 to operate and maintain a population-based cancer reporting system, reporting periodically estimates of cancer incidence and mortality in the United States. The Surveillance, Epidemiology, and End Results (SEER) Program is a continuing project of the National Cancer Institute of the National Institutes of Health. Among its goals, in addition to assembling and reporting cancer statistics, are the monitoring of annual cancer incident trends and the promoting of studies designed to identify factors amenable to cancer control interventions. (From National Cancer Institute, NIH Publication No. 91-3074, October 1990)
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Tumors or cancer of the LIVER.
The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.
They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.
A malignant epithelial tumor with a glandular organization.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Certain tumors that 1, arise in organs that are normally dependent on specific hormones and 2, are stimulated or caused to regress by manipulation of the endocrine environment.
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
A condition due to a deficiency of one or more essential vitamins. (Dorland, 27th ed)
Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.
An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.
Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
Antibodies produced by a single clone of cells.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
Most oral cancers involve the lips, lateral border of the tongue, floor of the mouth, and the area behind the third molars i.e ... Oral cancer is a malignant abnormal excessive growth of cells within the oral cavity, which arises from premalignant lesions ... The risk factors of oral cancer may include caries prevalence, oral hygiene status, dental trauma, dental visit, stress, family ... "Oral Cancer: Prevention, Early Detection, and Treatment", Cancer: Disease Control Priorities, Third Edition (Volume 3), The ...
"Benign Cementoblastoma , Mouth Cancer , Oral Cancer". www.knowcancer.com. Retrieved 2020-12-06. Subramani, Vijayanirmala; ... It is found most commonly in the mandible in the region of the lower molar teeth, occurring between the ages of 8 to 30 in both ... Çalışkan, A.; Karöz, T. B.; Sumer, M.; Açıkgöz, A.; Süllü, Y. (2016). "Europe PMC". Journal of the Korean Association of Oral ... The young child was referred to the Oral and Maxillofacial Surgery Department of Tehran University of Medical Sciences and upon ...
Those who inquired about his health were told he had terminal cancer. He then put his practice up for sale, later selling it to ... Acer then saw an oral surgeon who took a biopsy of the roof of his mouth. Rolf Wolfrom diagnosed Acer as having Kaposi's ... In December 1987, Acer treated Kimberly Bergalis for two abscessed molars and continued to see other patients, well into 1988. ... He began taking AZT and getting treatment at the VA Medical Center for the oral lesions. When he returned to Gutierrez in ...
When oral cancer does occur, it is usually seen on the soft tissues of the mouth such as the cheeks and tongue-not the rood of ... Buccal exostoses are found on the buccal aspect of the mandible or maxilla and commonly near the premolars and molars. Palatal ... Any abnormal growth on the body should be further investigated, but oral cancer is rare. Occurring in just 0.11 percent of men ... Oral torus is a bony growth in the upper or lower jaws. Tori (plural for oral torus) are not particularly common - about 5 - 10 ...
Oral cancerOral hygiene • Oral irrigator • Oral medicine • Oral microbiology • Oral mucosa • Oral pathology • Oral Surgery ... Mandibular second molar • Mandibular second premolar • Mandibular third molar • Manipal College of Dental Sciences, Manipal • ... Oral-B • Oral candidiasis • Oral and maxillofacial radiology • Oral and maxillofacial surgery • ... Maxillary first molar • Maxillary first premolar • Maxillary lateral incisor • Maxillary second molar • Maxillary second ...
Oral Health Group[edit]. Updated: Jan 7 2020 Adhesives for bonded molar tubes during fixed brace treatment PMID 28230910 https ... Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions ... Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors PMID ... Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy ...
Lee, FY; Workman, P; Roberts, JT; Bleehen, NM (1985). "Clinical Pharmacokinetics of Oral CCNU (lomustine)". Cancer Chemotherapy ... "BC Cancer Agency Cancer Drug Manual. Lomustine (CCNU; CeeNU)" (PDF). Retrieved 15 July 2016.. ... Cancer Drug Price Rises 1400% With No Generic to Challenge It, Peter Loftus, The Wall Street Journal, 12/26/2017 [FREE] ... "NextSource Biotechnology Gains FDA Approval for Use of Tradename Gleostine (lomustine), an Anti-Cancer Chemotherapy Agent". www ...
The surface of the oral cavity between the teeth and the inner side of the lips are called the oral vestibule. Surrounding the ... Mouth infections typically originate from dental caries at the root of molars and premolars that spread to adjacent structures ... In cases that spread to adjacent structures or in immunocompromised patients (cancer, diabetes, transplant immunosuppression), ... Mouth infections, also known as oral infections, are a group of infections that occur around the oral cavity. They include ...
Evidence shows that there is a relationship of smoking to periodontal disease, wound healing and oral cancers. Nicotine being a ... Ankylosis usually occurs in primary molars, however this can also take place in other primary teeth, as well as secondary ... The relationship between oral health and systemic health has become an increasingly important subject. Studies have suggested ... Naci A (2013). Ten Cate's Oral Histology. Elsevier. p. 274. ISBN 978-0-323-07846-7. Strydom H, Maltha JC, Kuijpers-Jagtman AM, ...
1800 mg/kg (rat, oral). 490 mg/kg (rat, oral). 1200 mg/kg (guinea pig, oral). 533 mg/kg (mouse, oral)[12]. ... Molar mass [g/mol]. Melting point [°C]. Boiling point [°C]. Density [g/cm3]. Refractive index ... Under California's Proposition 65, naphthalene is listed as "known to the State to cause cancer".[38] A probable mechanism for ... "Mothballs, air fresheners and cancer". Environmental Health Association of Nova Scotia. Environmental Health Association of ...
Another aspect of the field is managing the dental and oral condition of medically compromised patients such as cancer patients ... This is the exiting duct from the parotid gland which is commonly found adjacent to the upper second molar on the buccal mucosa ... Oral Medicine is defined by the American Academy of Oral Medicine as the discipline of dentistry concerned with the oral health ... "What is Oral Medicine?". British Society for Oral Medicine. Retrieved 7 December 2014. "Specialty Training Curriculum for Oral ...
Smoot, Betty (2015-06-01). "Effect of low-level laser therapy on pain and swelling in women with breast cancer-related ... Oberoi, Sapna (2014-01-01). "Effect of prophylactic low level laser therapy on oral mucositis: a systematic review and meta- ... and meta-analysis on the efficacy of low-level laser therapy in the management of complication after mandibular third molar ... Journal of Oral Rehabilitation 42 (4): 291-299. doi:10.1111/joor.12258. ISSN 1365-2842. PMID 25491183.. ...
August 2010). "A systematic review of viral infections associated with oral involvement in cancer patients: a spotlight on ... Molar mass. 324.336 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... Oral and genital herpes simplex (treatment and prevention). *Reduction of HSV transmission from people with recurrent infection ... Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55%) than aciclovir ...
In mice with cancer, 4-hexylresorcinol inhibited NF-κB and extended their survival rate.[4] ... in a 0.1% solution) for oral pain relief and as an antiseptic. ... Molar mass. 194.27. 3D model (JSmol). *Interactive image. ...
Her cause of death is assumed to be due to the metastatic cancer, complications of diabetes, or an abscessed molar that was ... Her poor oral health combined with her weight may indicate she had diabetes. Her brain was not removed. Her heart is preserved ... When it was CT-scanned in 2007, it was found to contain a mummified liver and intestine, as well as a molar tooth that lacks ... The tooth was found to match the size, shape, and density of the remaining molars, as well as lacking the same root that is ...
People undergoing surgery with cancer are at an increased risk of blood clots. Blood thinners are used to prevent clots, these ... These would be losing weight, increasing exercise and the cessation of oral contraceptives. Moving during periods of travel is ... cerebral complications abortion ectopic pregnancy molar pregnancy pregnancy childbirth and the puerperium coronary portal vein ... The risk of developing blood clots can be modified by life style modifications, the discontinuation of oral contraceptives, and ...
Residents may work closely with oral and maxillofacial surgeons, allowing them to improve their skills in oral surgical ... residents may expand their understanding of and increase their skill in third molar extraction, biopsy technique, pathology ... is best demonstrated in tumor boards where both medical and dental residents discuss and treatment plan head and neck cancer ... GPR residents may also become familiar with performing dental/oral surgical procedures in the operating room and managing the ...
J. Cancer. 103 (2): 239-48. doi:10.1038/sj.bjc.6605745. PMC 2906739. PMID 20571494.. ... and to increase the oral bioavailability of gallium[5] and iron.[6] ... Molar mass 126.11 g·mol−1 Density 1.348 g/cm3 Melting point 161 to 162 °C (322 to 324 °F; 434 to 435 K) ... showed limited in vitro antiproliferative activity towards cancer cells lines, perhaps inducing apoptosis in these cells.[7][8] ...
In 2002, he received recognition as a medical specialist for oral and maxillofacial surgery and in Oral Surgery. In 2005 he ... F. Hölzle, K.-D. Wolff: Anatomic position of the lingual nerve in the mandibular third molar region with special consideration ... International Cancer Organization) 2016-2018 Executive Member 2018-2020 President DÖSAK 2007 Winner of the Martin-Wassmund- ... In: Br J Oral Maxillofac Surg. 2017 Nov;55(9):946-951. doi: 10.1016/j.bjoms.2017.09.005. Epub 2017 Oct 21. Erratum in: Br J ...
... , sold under the brand name Gleevec among others, is an oral chemotherapy medication used to treat cancer.[2] ... "Cancer Stat Facts: Leukemia - Chronic Myeloid Leukemia (CML)". Cancer.gov. Retrieved 17 April 2020.. ... In 2013, more than 100 cancer specialists published a letter in Blood saying that the prices of many new cancer drugs, ... History of cancer chemotherapy. References[edit]. *^ a b "Imatinib (Gleevec) Use During Pregnancy". Drugs.com. 27 August 2018. ...
... cervical cancer, vaginal cancer or uterine cancer). In young children, or elderly adults with cognitive impairment, the source ... The risk of breakthrough bleeding with oral contraceptives is greater if pills are missed. The Not Classified category of the ... Other causes include miscarriage, ectopic pregnancy, molar pregnancy, incompetent cervix, uterine rupture, and preterm labor. ... About 10% of cases are due to endometrial cancer. Uterine fibroids are benign tumors made of muscle cells and other tissues ...
The condition is remotely linked to oral cancers and is associated with areca nut and / or its by-products chewing, majorly ... coffee Forgoing alcohol Employing a dental surgeon to round off sharp teeth and extract third molars Interprofessional ... 3 (3): 40-9. Pindborg JJ, Sirsat SM (December 1966). "Oral submucous fibrosis". Oral Surgery, Oral Medicine, and Oral Pathology ... Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 103 (2): 207-13. doi:10.1016/j.tripleo.2006.07. ...
The EPA rates the oral acute toxicity of dichlorprop as "slight" based on a rat LD50 of 537 mg/kg, and its derivatives are even ... CHLOROPHENOXY HERBICIDES (Group 2B), International Agency for Research on Cancer (IARC), 1987 ... Molar mass 235.064 g/mol Appearance white solid Melting point 116 to 120 °C (241 to 248 °F; 389 to 393 K) R-isomer ... and in 1987 the International Agency for Research on Cancer (IARC) ranked this class of compounds as group 2B "possibly ...
Oral-antral communicationEdit. A variant of the Valsalva maneuver is used to aid diagnosis of oral-antral communication, i.e. ... Valsalva is also used by dentists following extraction of a maxillary molar tooth. The maneuver is performed to determine if a ... Enlargement of the supraclavicular lymph nodes, is a diagnostic indicator of cancer. The prevalence of malignancy in the ... the existence of a connection between the oral cavity and the maxillary sinus.[22] ...
... and South American dental school graduates in third molar surgery: is there a difference?". J Oral Maxillofac Surg. 65 (4): 658 ... celiac disease or cancer. Many studies have also shown that gum disease is associated with an increased risk of diabetes, heart ... Oral and maxillofacial radiology - The study and radiologic interpretation of oral and maxillofacial diseases. Oral and ... Oral Radiology, Oral Maxillofacial Surgery, Oral Medicine, Orofacial Pain, Pathology, Orthodontics, Pediatric Dentistry, ...
... for systemic administration is available as an oral tablet, an intramuscular injection, and as a solution for ... Levothyroxine is also used as interventional therapy in people with nodular thyroid disease or thyroid cancer to suppress ... For oral tablets, the inability to swallow capsules serves as an additional contraindication.[15] ... Molar mass. 776.87 g·mol−1. 3D model (JSmol). *Interactive image. Melting point. 231 to 233 °C (448 to 451 °F) [3]. ...
According to the International Agency for Research on Cancer, bergapten is probably carcinogenic to humans.[6] ... With psoriasis, bergapten has been valued as an oral photochemotherapy treatment for its efficacy and lack of phototoxic and ... Molar mass 216.192 g/mol Pharmacology ATC code. D05BA03 (WHO) Except where otherwise noted, data are given for materials in ... A particular study that this was possible through the up-regulation of PTEN gene expression in those breast cancer cells.[11] ...
Limited toxic effects have been seen after oral administration of the toxin to animals. The mechanism by which YTX exerts a ... The sensitivity of these techniques can, however, be poor due to the low molar absorptivity of the analytes. The technique ... Korsnes, Mónica S.; Korsnes, Reinert (2018). "Single-Cell Tracking of A549 Lung Cancer Cells Exposed to a Marine Toxin Reveals ... These type of toxins can cause extreme gastrointestinal upset and accelerate cancer growth. Once scientists realized YTXs did ...
This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi sarcoma, cervical cancer, and pancreatic ... Moreover, Paclitaxel has been used in vitro to inhibit insulin fibrillation; in a molar ratio of 10:1 (insulin:paclitaxel), it ... Peltier S, Oger JM, Lagarce F, Couet W, Benoît JP (June 2006). "Enhanced oral paclitaxel bioavailability after administration ... Meanwhile, taxol began to be well known in the cell biology, as well as the cancer community, with a publication in early 1979 ...
Ovarian cancer: The recognition and initial management of ovarian cancer Archived 2013-09-22 at the Wayback Machine, Appendix D ... Grimes, DA; Jones, LB; Lopez, LM; Schulz, KF (29 April 2014). "Oral contraceptives for functional ovarian cysts". The Cochrane ... Ovarian hyperstimulation occurs more often with invasive moles and choriocarcinoma than complete molar pregnancies. A widely ... Ovarian cysts are present in about 16% of women after menopause and if present are more likely to be cancer. Some or all of the ...
... in patients with HER2-positive metastatic breast cancer progressing after trastuzumab". Breast Cancer Research and Treatment. ... Molar mass. 485.937 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... "Breast Cancer Research and Treatment. 134 (3): 1149-59. doi:10.1007/s10549-012-2126-1. PMC 3409367. PMID 22763464.. ... although there is emerging evidence to support its use in other cancers such as breast cancer.[9] ...
American Cancer Society Complete Guide to Complementary and Alternative Cancer Therapies (2nd ed.). American Cancer Society. ... In preliminary human studies, oral intake of quercetin in doses up to one gram per day over three months did not cause adverse ... Molar mass 302.236 g/mol Appearance yellow crystalline powder[1]. Density 1.799 g/cm3. ... Murakami A, Ashida H, Terao J (2008). "Multitargeted cancer prevention by quercetin". (review). Cancer Letters. 269 (2): 315-25 ...
381 mg/kg (guinea pig, oral). 300 mg/kg (rat, oral). 425 mg/kg (hamster, oral). 242 mg/kg (mouse, oral)[2] ... Cancer mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. N Engl J Med. 1991;324:212-218. ... Molar mass 255.48 g/mol Appearance Off-white to yellow crystalline solid ...
It is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to ... A short course of oral prednisolone may be required. Some dermatologists favour a few weeks of pre-treatment with oral ... Molar mass. 300.44 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... "Isotretinoin (Oral Route) Description and Brand Names - Mayo Clinic".. *^ Merritt B, Burkhart CN, Morrell DS (June 2009). "Use ...
"Pentamidine (Oral Inhalation) (Professional Patient Advice) - Drugs.com". www.drugs.com. Archived from the original on 2016-11- ... "Cancer Research. 67 (23): 11359-67. doi:10.1158/0008-5472.CAN-07-2235. PMID 18056463.. ... Molar mass. 340.427 g·mol−1. 3D model (JSmol). *Interactive image. Melting point. 186 °C (367 °F) (dec.). ...
"Is there a role for oral or intravenous ascorbate (vitamin C) in treating patients with cancer? A systematic review". The ... Cancer[edit]. There are two approaches to the question of whether vitamin C has an impact on cancer. First, within the normal ... and E and breast cancer risk: a meta-analysis and meta-regression". Cancer Causes & Control. 22 (10): 1383-96. doi:10.1007/ ... "Intravenous Vitamin C and Cancer: A Systematic Review". Integrative Cancer Therapies. 13 (4): 280-300. doi:10.1177/ ...
According to the International Agency for Research on Cancer, bergapten is probably carcinogenic to humans.[6] ... With psoriasis, bergapten has been valued as an oral photochemotherapy treatment for its efficacy and lack of phototoxic and ... Molar mass 216.192 g/mol Pharmacology ATC code. D05BA03 (WHO) Except where otherwise noted, data are given for materials in ... One study suggested that this was possible through the up-regulation of PTEN gene expression in those breast cancer cells.[11] ...
Most of the oral cavity is lined with oral mucosa, a mucous membrane that produces a lubricating mucus, of which only a small ... Both of these IBDs can give an increased risk of the development of colorectal cancer. Ulcerative coliltis is the most common ... premolars and molars are used for chewing and grinding. Mastication of the food with the help of saliva and mucus results in ... Ten Cate's Oral Histology, Nanci, Elsevier, 2007, page 321 *^ a b Britannica Concise Encyclopedia. Encyclopedia Britannica, Inc ...
Application of Tranylcypromine and Its Derivatives in Cancer Treatment". Current Topics in Medicinal Chemistry. 16 (19): 2179- ... Molar mass. 133.19 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... Genes promoted downstream of LSD1 are involved in cancer cell growth and metastasis, and several tumor cells express high ... analogues with more potent and selective LSD1 inhibitory activity are being researched in the potential treatment of cancers.[ ...
Medications used to treat cancer can interact with ketorolac along with radiation therapy. The risk of toxicity to the kidneys ... with oral therapy used as a continuation after the initial IM or IV dose.[8][13] ... Molar mass. 255.273 g·mol−1. 3D model (JSmol). *Interactive image. Chirality. Racemic mixture. ...
American Cancer Society Complete Guide to Complementary and Alternative Cancer Therapies (2nd ed.). American Cancer Society. pp ... Similar to silicon and aluminum, natural germanium compounds tend to be insoluble in water and thus have little oral toxicity. ... Molar heat capacity. 23.222 J/(mol·K) Vapor pressure. P (Pa) 1 10 100 1 k 10 k 100 k ... have been marketed as an alternative medicine capable of treating leukemia and lung cancer.[22] There is, however, no medical ...
Cancer[edit]. Studies on folic acid intake from food and folate supplementation with regards to cancer risk are based on the ... Folate deficiency is treated with supplemental oral folic acid of 400 to 1000 μg per day. This treatment is very successful in ... Glynn, SA; Albanes, D (1994). "Folate and cancer: a review of the literature". Nutrition and cancer. 22 (2): 101-119. doi: ... "Common questions about diet and cancer: Folate and folic acid". American Cancer Society. 2017. Archived from the original on 13 ...
... increasing the susceptibility of hypoxic cancer cells to radiation therapy, in patients with a form of brain cancer known as ... May 2011). "The pharmacokinetic profile of crocetin in healthy adult human volunteers after a single oral administration". ... Molar mass 328.408 g·mol−1 Appearance Red crystals Melting point 285 °C (545 °F; 558 K) ... A 2009 study involving 14 individuals indicated that oral administration of crocetin may decrease the effects of physical ...
... has been shown to effectively do this in certain cancer cells.[9] ... Molar mass. 201.249 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... Сmax 1-2 hours (oral administration). Metabolism. GI tract. Elimination half-life. 8 hours. ...
A single oral dose of ivermectin, taken once or twice a year for the 10-15-year lifespan of the adult worms, is required to ... European Journal of Cancer. 32A (6): 985-90. doi:10.1016/0959-8049(96)00063-9. PMID 8763339.. ... Panahi Y, Poursaleh Z, Goldust M (2015). "The efficacy of topical and oral ivermectin in the treatment of human scabies". ... Molar mass. 875.10 g/mol. 3D model (JSmol). *Interactive image. SMILES. *. CC[[email protected]](C)[[email protected]@H]1[[email protected]](CC[[email protected]@]2(O1)C[[email protected]@H]3C[[email protected]](O2 ...
Ingestion of melamine may lead to reproductive damage, or bladder or kidney stones, which can lead to bladder cancer.[20][26][ ... Melamine is reported to have an oral Median lethal dose (LD50) of 3248 mg/kg based on rat data. It is also an irritant when ... Molar mass. 126.12 g·mol−1. Appearance. White solid. Density. 1.574 g/cm3. ... 3850 mg/kg (rat, oral). Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], ...
"Calif approves use of pesticide linked to cancer". San Francisco Chronicle. December 1, 2010.. [dead link] ... Methyl iodide has an LD50 for oral administration to rats 76 mg/kg, and in the liver it undergoes rapid conversion to S-methyl ... MeI can also be used to prepare dimethylmercury, by reacting 2 moles of MeI with a 2/1-molar sodium amalgam (2 moles of sodium ... However this finding is disputed by the Pesticide Action Network which states that the EPA's cancer rating "appears to be based ...
... and the potential of masking stomach cancer.[1] It is also linked to an increased risk of Clostridium difficile colitis.[4] It ... Molar mass. 314.4 g/mol g·mol−1. 3D model (JSmol). *Interactive image ... Absorption: Oral: 50% Protein binding: 15% Metabolism: N-oxide is the principal metabolite. ...
Cancer prevention[edit]. Aspirin is thought to reduce the overall risk of both getting cancer and dying from cancer.[56] This ... "Oral Aspirin information". First DataBank. Archived from the original on 18 September 2000. Retrieved 8 May 2008.. ... It may also slightly reduce the risk of endometrial cancer,[61] breast cancer, and prostate cancer.[62] ... It may also decrease the risk of certain types of cancer, particularly colorectal cancer.[5] For pain or fever, effects ...
CancerEdit. A 2013 review by the National Cancer Institutes found evidence for use to be inconclusive.[107] A 2005 review of ... "Melatonin- Oral". Government of Canada. Health Canada. 28 August 2018. Retrieved 9 January 2019.. ... National Cancer Institute (May 2013). "Topics in complementary and alternative therapies (PDQ)". National Cancer Institute, ... Mills E, Wu P, Seely D, Guyatt G (November 2005). "Melatonin in the treatment of cancer: a systematic review of randomized ...
RNAi drugs treat cancer by silencing certain cancer promoting genes.[166] This is done by complementing the cancer genes with ... In some organisms, this process spreads systemically, despite the initially limited molar concentrations of siRNA. ... "Corn rootworm-active RNA DvSnf7: Repeat dose oral toxicology assessment in support of human and mammalian safety". Regulatory ... Advanced cancers I Recruiting MD Anderson Cancer Center NCT01591356 Atu027 PKN3 LNP Solid tumours I Completed Silence ...
Stern J, Ippoliti C (November 2003). "Management of acute cancer treatment-induced diarrhea". Seminars in Oncology Nursing. 19 ... Molar mass. 452.598 g·mol−1. 3D model (JSmol). *Interactive image. SMILES ...
... is suspected of causing cancer (i.e., carcinogenic) as per the International Agency for Research on Cancer (IARC) ... Serious illness has followed ingestion of 7.5 g (0.26 oz). The mean lethal oral dose for an adult is estimated at about 45 g ( ... Molar mass 7002119370000000000♠119.37 g·mol−1 Appearance Colorless liquid Odor Misleadingly-pleasant ethereal odor, leading to ... It is well absorbed, metabolized, and eliminated rapidly by mammals after oral, inhalation, or dermal exposure. Accidental ...
DMSO information from American Cancer Society *^ Hanslick, JL; Lau, K; Noguchi, KK; Olney, JW; Zorumski, CF; Mennerick, S; ... DMSO adalah pelarut non-toksik dengan median dosis letal lebih tinggi dari etanol (DMSO: LD50 Oral-Tikus-14,500 mg/kg,[18] ... Massa molar 78,13 g·mol−1 Penampilan Cairan tak berwarna Densitas 1.1004 g cm−3 ... Etanol: LD50 Oral-Tikus-7,060 mg/kg [19]). Uji klinis awal dengan DMSO dihentikan karena pertanyaan tentang keselamatannya, ...
Dying from cancer, he asked his wife on 22 November 1963 to inject him with 100 µg of LSD. He died later that day.[200] ... a single mid-range 200 μg oral dose of LSD was found to produce mean maximal concentrations of 4.5 ng/mL at a median of 1.5 ... Cancer and pregnancy. The mutagenic potential of LSD is unclear. Overall, the evidence seems to point to limited or no effect ... Since 2008 there has been ongoing research into using LSD to alleviate anxiety for terminally ill cancer patients coping with ...
... certain cancers, multiple sclerosis, and as add-on therapy for tuberculosis.[1] It is given by mouth, by injection into a vein ... Medrol dose packs are prepackaged forms of regular methylprednisolone for oral use. [13] ... Molar mass. 374.471 g/mol g·mol−1. 3D model (JSmol). *Interactive image ...
... ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma.[4] As an immune suppressor it is used in ... Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) in the ... CancerEdit. Cyclophosphamide is carcinogenic and may increase the risk of developing lymphomas, leukemia, skin cancer, ... "Cancer Research. 49 (1): 1-7. PMID 2491747.. *^ Institute for Safe Medication Practices, ISMP's List of Error-Prone ...
No association is seen between PPI use and cancer, but use of PPIs may mask gastric cancers or other serious gastric problems ... Omeprazole is also available as an oral suspension of enteric-coated beads in the UK as an unlicensed product. Oral suspensions ... Most oral omeprazole preparations are enteric-coated, due to the rapid degradation of the drug in the acidic conditions of the ... Daly AK, King BP (May 2003). "Pharmacogenetics of oral anticoagulants". Pharmacogenetics. 13 (5): 247-52. doi:10.1097/00008571- ...
... the cancer on and off through tetracycline administration. This could be used to grow the cancer in mice and then halt it at a ... "Bait ingestion by free-ranging raccoons and nontarget species in an oral rabies vaccine field trial in Florida". J. Wildl. Dis ... Molar mass. 444.435 g/mol. 3D model (JSmol). *Interactive image. SMILES. *. C[[email protected]]1(c2cccc(c2C(=O)C3=C([[email protected]]4([[email protected]@H](C[[email protected]@H]31)[C ...
Molars coming in at this age might feel like a bigger hurdle in your childs oral development. Luckily, there are things you ... The use of tobacco products and alcohol increases the risk of oral cancer. Most oral cancers are first diagnosed by the dentist ... Oral Care for Molar Eruption. With the eruption of their molars, children have a complete set of 20 primary teeth, and learning ... men over the age of 40 have the greatest risk for oral cancer. About approximately 43,000 people will be diagnosed with cancer ...
Molar Pregnancy see Tumors and Pregnancy * Mouth Cancer see Oral Cancer * Multiple Myeloma ... Paranasal Sinus Cancer see Nasal Cancer * Parotid Gland Cancer see Salivary Gland Cancer ... Small Cell Lung Cancer see Lung Cancer * Small Intestine Cancer see Intestinal Cancer ...
205) 996-2799 Research Interests: Head and neck cancer survival; Predicting cancer risk in oral premalignant lesions; Mapping ... of ameloblastomas using fluorescence imaging; Functional outcomes in head and neck cancer surgery; Third molar surgery; ... 205) 934-5334 Research Interests: Oral cancer; Prosthodontics; Implants; Dental oncology; Facial prosthetics; Obturators; ... SDB 419 Research Interests: Oral Surgery; Craniofacial and Cleft Lip/Palate Surgery; Benign Pediatric Oral and Maxillofacial ...
Oral cancer biology and therapy; Oral microenvironment and cancer Faculty Profile ... Functional outcomes in head and neck cancer surgery; Third molar surgery; Craniomaxillofacial trauma Faculty Profile ... 205) 996-2799 Research Interests: Head and neck cancer survival; Predicting cancer risk in oral premalignant lesions; Mapping ... 205) 934-5334 Research Interests: Oral cancer; Prosthodontics; Implants; Dental oncology; Facial prosthetics; Obturators; ...
Oral Cancer Screening Our office utilizes a VELScope method of screening for Oral Cancer. This is complimentary with your New ... Services at the clinic include examinations and professional dental cleaning, Velscope oral cancer screening, general and ...
A study has found that a persons first permanent molars carry a lifelong record of health information dating back to the ... New research could prevent jaw damage for cancer patients in need of oral surgery LOS ANGELES, U.S.: To this day, there is no ... The first permanent molars start forming in utero and retain a record of vitamin D intake dating back to the mothers pregnancy ... The girls undescended molar showed that her mother had suffered a vitamin D deficiency during pregnancy-a possible clue to the ...
When Patricia Lines came to MD Anderson for her oral cancer treatment, she was impressed by the way all the different parts of ... When Patricia Lines came to MD Anderson for her oral cancer treatment, she was impressed by the way all the different parts of ... Eventually, Patricia lost the two remaining upper molars that had anchored the prosthesis. With so much radiation to this area ... Life after oral cancer treatment. During cancer treatment, Patricia experienced her share of ups and downs. During radiation, ...
Poor oral hygiene and smoking are two of many probable causes of oral cancer. Oral Surgery: Surgical procedures of the mouth. ... Molars: The teeth located in the back of the mouth which have larger biting surfaces, adapted for grinding food. Normally, ... Oral Cancer: The condition in which cancerous cells are present in the tissues of the mouth. ... Oral surgeries can be conducted for a variety of dental purposes including the prevention of oral diseases, treatment of dental ...
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Good oral hygiene is the to healthy teeth during old age. Correct brushing techniques and regular dental check-ups can help ... Excessive drinking is a risk factor for throat and oral cancers.. *Make sure that you get dental treatment done before cancer ... Do you know how many canines or molar teeth you have and what is their function? Find out from this interactive calculator. ... Dental problems can lead to other chronic medical diseases such as heart disease and stroke, lung infections and oral cancer. ...
Fusobacteria which are found in the mouth can turn on cancer growth genes to generate colorectal cancer, reveal studies. ... Oral Health And AIDS. AIDS has taken on massive proportions in modern times. It is estimated that over 15 million people are ... Do you know how many canines or molar teeth you have and what is their function? Find out from this interactive calculator. ... Tongue Abnormalities Shigellosis Cancer and Homeopathy Colo-rectal cancer - Management Colorectal Cancer Cancer Facts Cancer ...
S-1 is an oral fluoropyrimidine derivative that combines tegafur (FT) with two modulators; 5-chloro-2, 4-dihydroxypyridine ( ... CDHP) and oteracil potassium (Oxo) in a 1:0.4:1 molar concentration ratio. The phase II trials of a combination of gemcitabine ... Pancreatic ductal adenocarcinoma, also known as pancreatic cancer, is an eighth cause of cancer-related deaths in the world. ... Any previous or concurrent malignancy other than non-melanoma skin cancer or in situ cancer of uterine cervix ...
People receiving cancer drugs may develop infected teeth because these drugs weaken the immune system. Infected teeth may need ... Wisdom teeth, also called third molars, are often extracted either before or after they erupt in the mouth. They commonly come ... Oral maxillofacial surgeons typically perform this procedure, though general dentists can also perform them. The doctor makes a ...
Vocabulary for F09 Oral Path 2a. Find, create, and access Erythema, flashcards with Course Hero. ... Fourth molar aka ____. True or False?. HPV+ cancers have a better prognosis than HPV- ones. True ... Xeroderma Pigmentosum is an AR condition that predisposes people to what type of oral cancer? cancer of skin, lower lip, and ... This represents more than 90% of oral cancers Squamous Cell Carcinoma of the oral mucosa ...
BMA Medical Book Awards 2015 An Introduction to Oral and Maxillofacial Surgery encompasses the full range of oral and ... Oral Cancer Reconstruction of the Mouth, Jaws and Face Facial Aesthetic Surgery ... Third Molar Surgery. Dentoalveolar Surgery for Orthodontic Treatment. Orofacial Infections. Cysts of the Jaws ... R.J.G. Stevens, Department of Oral & Maxillofacial Surgery, Frenchay Hospital, Bristol, UK in British Journal of Oral and ...
... based combination protocols for gastrointestinal cancer. Promising results were seen with 5-FU/leucovorin in combination with ... UFT is an orally administered fixed combination of tegafur anduracil in a 1:4 molar ratio. Tegafur (1-[2-tetrahydrofuryl]-5- ... Brain CancerBreast CancerGastrointestinal CancerGenitourinary CancerGynecologic CancerHematologyLeukemiaLung CancerLymphoma ... Assessing the Impact of Tailor XColorectal CancerGastrointestinal CancerGastrointestinal Cancer QuizHead & Neck CancerHER2- ...
Drugs and schedule. UFT, a 5-FU oral prodrug, consists of a 4:1 molar combination of uracil and tegafur ( 12, 14). Tegafur, ... Cancer Research Online ISSN: 1538-7445. Cancer Research Print ISSN: 0008-5472. Journal of Cancer Research ISSN: 0099-7013. ... oral cyclophosphamide plus oral methotrexate for the clinical treatment of metastatic breast cancer ( 9) or cyclophosphamide ... Low dose oral methotrexate and cyclophosphamide in metastatic breast cancer: antitumor activity and correlation with vascular ...
ABH isoantigens in cancer of oral tissues. Tittiranonda, Thanu Tittiranonda, Thanu Less ... Histopathologic findings in third molar opercula. Maustein, George Maustein, George Less Plastic and Reconstructive Surgery. 59 ... Effects of operation on immune response in cancer patients: sequential evaluation of in vitro lymphocyte function. Hurst, ... The prediction of lymph node metastases from oral squamous carcinoma. Bingham, Hal G. ...
... clarify the impact of cancer therapies on prevalence of osteoradionecrosis (ORN) in head and neck cancer... ... Risk of osteoradionecrosis after extraction of impacted third molars in irradiated head and neck cancer patients. J Oral ... High-dose rate interstitial brachytherapy for stage I-II tongue cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:667 ... Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:731-738CrossRefPubMedGoogle Scholar ...
Molar Bear Family Dental was welcomed to the area by The Little Elm Chamber with a ribbon cutting Ceremony. Dr. Wang and her ... Oral Cancer Screenings. Dr. Santilli at Honey Dental is very committed to her patients health when it comes to screening for ... Why? Early detection saves lives! In the U.S. alone, 41,350 new cases of oral cancer were discovered in 2013. In late stage… ... Santilli uses advanced non-invasive painless visualization technology to screen all her patients for oral cancer. ...
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Enrolled subjects will have a standard oral examination (including oral cancer screening) performed in the NIDCR clinic by ... Enamel chips cut from previously extracted third molars will be sterilized by ethylene oxide then inserted into the stent on ... Arrangement of Oral Microflora on Tooth Surfaces [ Time Frame: At 4 hours and 8 hours ] ... Researchers who study plaque know that many different types of oral bacteria stick to each other in test-tube experiments. ...
Animal Dentistry and Oral Surgery Specialists, LLC Oshkosh, Green Bay, Greenfield, Glendale. ... specializes in oral surgical oncology for pets with malignant melanoma, fibrosarcoma, squamous cell carcinoma & osteosarcoma. ... the first molar tooth.. Papillary squamous cell carcinoma in. a young dog.. This oral mass was a dentigerous cyst.. Histology ( ... Closer view of the above oral mass.. Side view of the same oral mass.. The oral mas was excised after an initial. biopsy was ...
21-7) Oral and pharyngeal cancer exam within past 12 months, aged 40+ years. 20. 13d. ... a) Children, aged 8 years (1st molars). 50. 28. b) Adolescents (1st and 2nd molars) aged 14 years. 50. 14. ... 3-6) Oral and pharyngeal cancer death rates reduction (per 100,000 population). 2.7. 3.0d*. ... 21-6) Oral and pharyngeal cancers detected at earliest stages, all 50. 35e. ...
Most oral cancers involve the lips, lateral border of the tongue, floor of the mouth, and the area behind the third molars i.e ... Oral cancer is a malignant abnormal excessive growth of cells within the oral cavity, which arises from premalignant lesions ... The risk factors of oral cancer may include caries prevalence, oral hygiene status, dental trauma, dental visit, stress, family ... "Oral Cancer: Prevention, Early Detection, and Treatment", Cancer: Disease Control Priorities, Third Edition (Volume 3), The ...
Why Fix a Baby Tooth or Childs Molar. Oral Cancer and Smokeless Tobacco ... How Can I Eliminate My Bad Oral Habits and Protect My Perfect Teeth?. The first step to eliminating a bad habit is to identify ... Identifying and eliminating bad oral habits is the key to retaining a great smile for many years. Sometimes we are not aware ... Composite fillings (tooth-colored fillings) can now be placed in the back molar areas when tooth decay is detected. These ...
Why Fix a Baby Tooth or Childs Molar. Oral Cancer and Smokeless Tobacco ... Commonly administered oral conscious sedatives include: Valium, Halcion, Dalmane, and Versed. Oral conscious sedation dentistry ... Oral Conscious Sedation Dentistry. Many dentists will prescribe a sedative drug to be taken by mouth prior to the planned ... Dentistry and Medicine - A Partnership for Your Oral Health. A world of opportunities for dental health awaits us in the new ...
S-1, an oral 5-FU-based anticancer drug, is indicated for the treatment of seven types of cancer in Japan, including gastric ... The molar ratio of tegafur, gimeracil and oteracil potassium in S-1 is 1.0:0.4:1.0 (1,2). Clinically, the time course of serum ... not only in advanced or recurrent colorectal cancer, but also in gastric cancer and breast cancer (22-25). In particular, TP ... Shirao K, Ohtsu A, Takada H, et al: Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma. Cancer. 100: ...
Your Mouth During Oral Cancer Treatment. Stainless Steel Dental Crowns For Childrens Molars - A Childrens Dentist Explains ... Your Mouth During Oral Cancer Treatment. Each year, many people are treated for oral cancer. Chemotherapy treatments for cancer ... The following are descriptions of oral problems that can occur with cancer treatment:. Infections of the oral cavity can be ... The patients ability and interest in maintaining oral health, as well as the ability to comply with an oral cancer prevention ...
  • Primary molars are normally the last teeth to erupt and the last to fall out, making way for your child's permanent first, second and third molars as described by the American Dental Association (ADA) . (colgate.com)
  • Your permanent first molars have a unique job: Known as the "six-year molars," per the ADA , they serve as the first "placeholders" in your mouth and set the stage for the shape of your lower jaw as it supports the placement of the rest of your teeth. (colgate.com)
  • With the eruption of their molars, children have a complete set of 20 primary teeth, and learning how to brush these teeth is important. (colgate.com)
  • Services at the clinic include examinations and professional dental cleaning, Velscope oral cancer screening, general and routine care, Invisalign adult orthodontics and the surgical insertion of implants to replace missing teeth. (whatclinic.com)
  • Do you know how many canines or molar teeth you have and what is their function? (medindia.net)
  • People receiving cancer drugs may develop infected teeth because these drugs weaken the immune system. (colgate.com)
  • Wisdom teeth, also called third molars, are often extracted either before or after they erupt in the mouth. (colgate.com)
  • Symptoms of oral cancer can include velvety red patches and white patches, loose teeth and non-healing mouth ulcers. (wikipedia.org)
  • If you have the above problems then the third molar or the wisdom teeth must be removed from the mouth with some treatment. (power-posts.com)
  • Periodontal disease is initiated by oral bacteria which adhere to the teeth in a substance called plaque. (vin.com)
  • The oral vestibule is the area between the cutaneous borders of the lips and the teeth. (ahns.info)
  • Except for the teeth, the surface of all oral cavity subsites consists of stratified squamous epithelium. (ahns.info)
  • The most common areas where plaque tends to accumulate are on the outside of the canines, or "fang" teeth, as well as the big molars at the back of the mouth, which are used for chewing. (whole-dog-journal.com)
  • The main teeth involved can include deciduous and permanent teeth, impacted molars and premolars. (wikipedia.org)
  • Surgery of teeth, mouth jaws and face is performed by a specialised oral and maxillofacial surgeon (OMS / OMFS) to correct a wide range of minor and major skeletal and dental irregularities, including the misalignment of jaws and teeth. (berlin-klinik.com)
  • Twenty primary (baby) teeth and baby molars are usually present by three years of age. (1stpediatricdentist.com)
  • Extractions of teeth, including impacted third molars (wisdom teeth). (huhealthcare.com)
  • Some oral causes for concern include any type of pain or discomfort, she said, as well as discolored teeth. (statecollege.com)
  • Most often, the sealants are applied to the back teeth, e.g., premolars and molars. (youroralhealth.ca)
  • For example, many people with heart conditions will be found to have a chronic infection at the site of their wisdom teeth - the third molars. (arizonaadvancedmedicine.com)
  • Certain molars are connected to the heart meridian and when those teeth are stressed with chronic infection, the heart is stressed. (arizonaadvancedmedicine.com)
  • Also called "third molars," wisdom teeth may become trapped beneath the gum line and behind the second molars. (mountsinai.org)
  • Teeth, gums, and the rest of the oral cavity need extra care and attention if you want them to stay healthy in your later years. (harvard.edu)
  • Today, three-quarters of people over 65 retain at least some of their natural teeth, but older people still suffer higher rates of gum disease, dental decay, oral cancer, mouth infections, and tooth loss. (harvard.edu)
  • Misaligned teeth - In order to ensure your best possible oral and dental health, your dentist may need to remove teeth that are incorrectly placed or not functioning well. (redondo-oralsurgery.com)
  • Dental extractions are most commonly performed on the wisdom teeth (or the third molars). (redondo-oralsurgery.com)
  • The straight teeth, bright smile and life-long oral health you envision really can be yours. (losangeleswisdomteeth.com)
  • The extraction of teeth, including wisdom teeth or third molars. (oralsurgeonhouston.com)
  • Small trial did not find evidence that preemptive use of acetaminophen or ibuprofen reduces perioperative pain in children undergoing primary molar extraction. (helsinki.fi)
  • The aim of this review was to the impact of secondary versus primary closure techniques on the frequency and severity of pain, facial swelling, trismus, infectious complications, and postoperative bleeding after impacted mandibular third molar extraction. (nationalelfservice.net)
  • Although differences between primary and secondary closure techniques after impacted mandibular third molar extraction are likely to be small, available evidence provides only low confidence in the effect estimates. (nationalelfservice.net)
  • Taste disorders may result from oral health problems and some surgeries (e.g. third molar extraction and middle ear surgery). (masseyeandear.org)
  • Choose something that melts in your mouth and clears the oral cavity quickly. (380news.com)
  • Oral cancer is a malignant abnormal excessive growth of cells within the oral cavity, which arises from premalignant lesions through a multistep carcinogenesis process. (wikipedia.org)
  • Infections of the oral cavity can be caused by the usual organisms found in the mouth or by opportunistic organisms not usually found in the mouth. (1stdentist.com)
  • Oral cancer is the most common type of head and neck cancer and includes lesions in the lips and in the oral cavity (buccal mucosa, hard palate, floor of the mouth, tongue, gums, retromolar trigone, and alveolar ridge). (springer.com)
  • Oral squamous cell carcinoma (OSCC) represents 90% of the neoplasms in the oral cavity and is characterized by an aggressive and invasive growth pattern that spreads to the cervical lymph nodes. (springer.com)
  • How do the social determinants of health manifest themselves in the oral cavity? (adea.org)
  • The oral cavity is comprised of several subsites, each of which contributes to its function. (ahns.info)
  • The tongue is the most important structure in the oral cavity in terms of function. (ahns.info)
  • The anterior two-thirds of the tongue, sometimes referred to as the "oral tongue," are located in the oral cavity, while the posterior one-third of the tongue, separated by the transverse row of circumvallate papillae, is located in the oropharynx. (ahns.info)
  • The superior limit of the oral cavity is made in large part by the hard palate, which serves to separate the oral cavity from the nasal cavity. (ahns.info)
  • Because of this structure, the vast majority of cancers of the oral cavity are squamous cell carcinomas. (ahns.info)
  • There are minor salivary glands distributed throughout all surfaces of the oral cavity, so cancers of salivary gland origin are also found. (ahns.info)
  • Since an overwhelming predominance of oral cavity cancers are squamous cell carcinomas, most information about risk factors relates to that histologic entity. (ahns.info)
  • Tobacco and alcohol use are the two strongest risk factors for oral cavity squamous cell carcinoma (OCSCC). (ahns.info)
  • benign and malignant lesions of the oral cavity, third molar removal and complications of third molar removal, Fascial space infections of the head and neck and management of the dental patient with spreading infection, understanding the anatomy of the cranial nerves, top tips in the management of upper respiratory tract infections. (plymouthhospitals.nhs.uk)
  • The parotid duct travels from thegland can you buy Lyrica online which is located below and in front ofthe ear, to enterthe oral cavity opposite the second upper molar tooth. (paperbookintensive.org)
  • Dr. Joseph Issels of Germany wrote that many cancer patients got well for example when root canals and other infections of the oral cavity were removed. (arizonaadvancedmedicine.com)
  • buccal phase: when food is still in oral cavity (voluntary swallowing) 2. (coursehero.com)
  • Our dedicated oral pathologist specializes in evaluating specimens of the jawbone and oral cavity to diagnose conditions such as cysts, salivary gland tumors, oral cancer, and disorders related to the jawbone, lip, and palate. (mountsinai.org)
  • Treatment for Colorectal Cancers may involve surgery,chemotherapy, radiation therapy or biological therapy. (medindia.net)
  • An Introduction to Oral and Maxillofacial Surgery encompasses the full range of oral and maxillofacial surgery. (routledge.com)
  • In the UK, oral and maxillofacial surgery is a unique discipline-the ninth of ten currently recognized surgical specialties-and trainees usually start from a dental qualification before gaining a medical one. (routledge.com)
  • I think this is an excellent introduction to oral and maxillofacial surgery for anyone with a little experience in the fi eld. (routledge.com)
  • What Is Oral and Maxillofacial Surgery? (routledge.com)
  • What is involved in oral surgery? (mypetsdentist.com)
  • What care is needed after oral surgery? (mypetsdentist.com)
  • The factors and people that helped to develop the subject of head and neck surgery have been traced through history, and this paper provides a broad historical perspective with which to compare the current standard of management for head and neck cancer. (kcl.ac.uk)
  • Written by expert surgeons and educators, Current Therapy in Oral and Maxillofacial Surgery covers the latest treatment strategies, surgical techniques, and potential complications in OMS. (elsevier.com)
  • Unemployed, lacking dental insurance and fighting cancer, a Hallandale Beach woman turned to an unlicensed dentist who performed oral surgery in her trailer home and accepted cash payments in installments. (sun-sentinel.com)
  • 25th international conference on Oral & Maxillofacial Surgery. (baoms.org.uk)
  • Despite vast amounts of research and advances in the fields of oncology and surgery, the 5-year survival rate for oral cancer has only modestly improved in the last 30 years and its prognosis remains poorer Kcnj12 compared to breast, colon, or prostate cancer [1]. (cylch.org)
  • All featured abstracts will be published in the official ACOMS member journal, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology . (acoms.org)
  • 1 Surgery is the main treatment for operable gastric cancer but recurrence rates are high and about 40% to 80% of patients develop relapsed disease after surgery. (hkmj.org)
  • Beginning with diagnosis, Mount Sinai's oral and maxillofacial surgery team uses the latest technologies to thoroughly evaluate and treat each patient's condition. (mountsinai.org)
  • Whether you need a minor oral procedure that can be done in our office, or a more complex operation to be performed at the hospital, our team of board certified oral and maxillofacial surgeons possesses specialized training so we can offer the newest available oral and maxillofacial surgery options. (mountsinai.org)
  • The Oral Surgery Experience You Can Count On. (redondo-oralsurgery.com)
  • After your oral surgeon completed the standard four years of dental school, they then went on to complete another four years in a hospital-based residency program specifically for mouth, jaw and head related reconstruction and surgery. (oralsurgeonhouston.com)
  • Oral and Maxillofacial Surgery is a specialty through the American Dental Association, it includes the diagnosis, surgical and everything attached to the treatment of either diseases, injuries or congenital defects of the hard and soft tissues of the oral and maxillofacial region for both functional and aesthetic purposes. (oralsurgeonhouston.com)
  • Reconstructive oral surgery, including impact injury or following oral cancer removal. (oralsurgeonhouston.com)
  • Located posterior to the mandibular third molar, the retromolar trigone is a triangular-shaped area in which keratinized mucosa covers a portion of the mandibular ramus. (ahns.info)
  • Is It the Same with Permanent Molars? (colgate.com)
  • Likewise, it's particularly important to schedule an appointment with your child's dentist to ensure permanent molars are erupting correctly alongside regular checkups. (colgate.com)
  • They have found that a person's first permanent molars carry a lifelong record of health information dating back to the prenatal phase, storing vital information that can connect maternal health to a child's health. (dental-tribune.com)
  • The first permanent molars start forming in utero and retain a record of vitamin D intake dating back to the mother's pregnancy. (dental-tribune.com)
  • We may recommend dental sealants for permanent molars or premolars that have very deep grooves or pitted surfaces. (effinghamsmiles.com)
  • Dental caries and periodontal disease are closely associated with the oral biofilm known as dental plaque. (clinicaltrials.gov)
  • According to a new study in this month's issue of Community Dentistry & Oral Epidemiology, overweight children or those at risk of becoming overweight may have a decreased risk of caries compared to children of normal weight. (drbicuspid.com)
  • Smoking is obviously linked to all sorts of oral pathologies-from increased caries and periodontal disease all the way to life-threatening diseases like oral cancer. (adea.org)
  • Dental problems can lead to other chronic medical diseases such as heart disease and stroke, lung infections and oral cancer . (medindia.net)
  • In the second study, Yiping Han of Case Western Reserve University School of Dental Medicine and her collaborators discovered that fusobacteria rely on a molecule called Fusobacterium adhesin A (FadA), which is found on the surface of these bacterial cells, to attach to and invade human colorectal cancer cells. (medindia.net)
  • Molar Bear Family Dental was welcomed to the area by The Little Elm Chamber with a ribbon cutting Ceremony. (380news.com)
  • Dr. Santilli at Honey Dental is very committed to her patient's health when it comes to screening for oral cancer during all dental check-ups. (380news.com)
  • The evaluation of every oral mass requires dental radiographs to determine if there is local invasion and to procure a deep biopsy to obtain a representative tissue sample. (mypetsdentist.com)
  • What can you expect with oral and dental tumors? (mypetsdentist.com)
  • Our goal is to provide quality dental care for your life-long oral health. (1stcosmeticdentist.com)
  • You'll feel relaxed during your dental appointment, and relieved that your oral health is in good hands. (1stsedationdentist.com)
  • Thoroughness: Advances in assessment and diagnosis now enable dentists to make thorough evaluations of your overall dental and oral health. (1stsedationdentist.com)
  • A fundamental purpose of dental education is to develop health professionals who will maintain and improve the oral health status of individuals and populations. (nap.edu)
  • One task, then, for this committee as it evaluated future directions for dental education was to examine the status of oral health in this country and the ramifications for dental education in both the short and the long-term. (nap.edu)
  • it then presents the committee's views on oral health status goals and their implications for dental education. (nap.edu)
  • The latest survey, which began in 1988 and does include oral health measures, is to be analyzed by the National Institute for Dental Research (NIDR) rather than NCHS, and results are yet to be published. (nap.edu)
  • April 9, 2008 -- More patients may be at risk of oral cancer than previously believed, warn Delta Dental of Michigan, Ohio, and Indiana. (drbicuspid.com)
  • Does a Dental Biopsy In My Mouth Mean I Have Oral Cancer? (1stwisdomteeth.com)
  • Two of the paper's authors-Kim Fenesy, D.M.D., Vice Dean, and Emily Sabato, Ed.D., Assistant Dean for Academic Affairs, both at Rutgers, The State University of New Jersey, School of Dental Medicine-recently spoke with ADEA CCI Liaison Ledger about the ways in which social determinants impact oral health and how Rutgers faculty have woven this subject matter into the predoctoral curriculum at their institution. (adea.org)
  • In order to maintain your oral health, it's important to schedule regular dental check-ups. (1stbraces.com)
  • Doctors and dentists sometimes mistake oral cancers for less-severe types of mouth sores or other dental problems. (medicalmalpracticehelp.com)
  • TIF) pone.0073348.s001.tif (436K) GUID:?4DDB4FD7-F538-4869-A6CD-131C67759747 Abstract Despite an improved knowledge of the pathogenesis of dental cancer, its treatment outcome remains poor. (cylch.org)
  • Most of all, the 599 peptide-mediated siRNA delivery advertised significant CIP2A mRNA and proteins silencing which led to decreased dental cancers cell invasiveness and anchorage-independent development. (cylch.org)
  • Collectively, these data demonstrate a chimeric peptide comprising a fusogenic series, in conjunction with cell-penetrating residues, may be used to efficiently Lacosamide reversible enzyme inhibition deliver siRNAs into dental cancers cells and induce the silencing of its focus on gene, supplying a new therapeutic strategy in combating oral cancer potentially. (cylch.org)
  • Important dental symptoms that should immediately lead your way to your dentist or directly to BERLIN-KLINIK International Hospital and International Dental Clinic include bleeding, pain, malocclusion new growths, numbness or paresthesias, and chewing problems prolonged dental symptoms may decrease oral intake, leading to weight loss. (berlin-klinik.com)
  • February is National Children's Dental Health Month, an initiative by the American Dental Association to raise awareness about the importance of oral health. (statecollege.com)
  • Oral cancer screening is usually a routine part of a dental examination. (youroralhealth.ca)
  • The files of the oral pathology diagnostic service at the University of Western Ontario, London, Ontario, which receives specimens from dentists and dental specialists from across the province of Ontario, were searched for cases of metastatic tumours to the jaws and oral soft tissues occurring between 1992 and 2010. (jcda.ca)
  • American Dental Association specialty recognition of oral medicine: Implications for the dental profession. (helsinki.fi)
  • Oral chronic graft-versus-host disease: What the general dental practitioner needs to know. (helsinki.fi)
  • A "healthy" cleaning and check-up consists of x-rays, an oral exam and a thorough cleaning (prophylaxis) by a registered dental hygienist. (tuscfamilydental.com)
  • We offer a range of dental services designed to help you maintain your oral health throughout your adult life. (losangeleswisdomteeth.com)
  • As a Dental Hygienist, you are considered to be a specially trained health care professional who help to maintain the dental health of patients and also prevent oral health problems that may occur due to poor oral hygiene habits and techniques (Dental Hygienist). (938169.com)
  • Mouth cancers can be rated as the 6th most common cancers internationally presently, with squamous cell carcinomas of the oral mucosa being the most common type (90%) [2], [3]. (cylch.org)
  • Some common causes of dry mouth are cancer therapy (radiation/chemotherapy), intake of certain medications, smoking and Sjorgren s syndrome . (medindia.net)
  • Single-agent chemotherapy with gemcitabine was considered as standard of care for patients with advanced pancreatic cancer, since Burris et al. (clinicaltrials.gov)
  • We tested a "doublet" combination metronomic chemotherapy treatment using two oral drugs, UFT, a 5-fluorouracil (5-FU) prodrug administered by gavage, and cyclophosphamide, for efficacy and toxicity in a new mouse model of advanced, terminal, metastatic human breast cancer. (aacrjournals.org)
  • We conclude that combination oral low-dose daily metronomic chemotherapy, using cyclophosphamide and UFT, is superior to monotherapy and seems to be a safe and highly effective experimental antimetastatic therapy, in this case, for advanced metastatic breast cancer. (aacrjournals.org)
  • Because standard (conventional maximum tolerated dose) chemotherapy treatment regimens frequently involve "doublet" combinations of such drugs, we asked whether significantly enhanced antitumor activity would also be observed using a concurrent all oral combination metronomic chemotherapy regimen involving two different drugs administered chronically on a daily basis with no breaks at optimal biological doses. (aacrjournals.org)
  • The aim of the present study was to investigate markers in surgically resected specimens of colorectal cancer that can be used to predict the response to chemotherapy. (spandidos-publications.com)
  • These results indicate that the mRNA expression of TP, a metabolizing enzyme of 5‑FU, is a significant predictor of response to post‑operative chemotherapy with S‑1 in patients with stage III colorectal cancer. (spandidos-publications.com)
  • 5-Fluorouracil (5-FU) continues to play a central role in chemotherapy for colorectal cancer. (spandidos-publications.com)
  • As a second-line chemotherapy for metastatic colorectal cancer, combination therapy with S-1 and irinotecan was shown to be non-inferior to a folinic acid, 5-FU and irinotecan (FOLFIRI) regime ( 6 ). (spandidos-publications.com)
  • Clinical trials have demonstrated that administering S-1 for one year is as effective as post-operative adjuvant chemotherapy in stage II or III gastric cancer. (spandidos-publications.com)
  • Chemotherapy treatments for cancer and radiation treatment for head and neck cancer often cause oral complications. (1stdentist.com)
  • About half of chemotherapy patients experience oral complications, particularly those being treated for leukemia and those who receive bone marrow transplants. (1stdentist.com)
  • Up to the present time, it has been the most used anticancer drug in the chemotherapy for lung cancer. (aacrjournals.org)
  • 2-5] Cancer patients also have higher rates of insufficiency or deficiency of Vitamin C. Chemotherapy can negatively impact the Vitamin C status of oncology patients. (cancertutor.com)
  • The use of adjuvant chemotherapy with S-1 (tegafur, gimeracil, and oteracil potassium) has been shown to improve the outcome of patients with gastric cancer. (hkmj.org)
  • Chemotherapy - Cancer treatments such as chemotherapy can weaken your immune system, leaving you more prone to tooth infections. (redondo-oralsurgery.com)
  • Multiple impacted second molars: a rare radiographic finding. (google.co.in)
  • Associate Professor/Section Chief of Oral Oncology This email address is being protected from spambots. (uab.edu)
  • From her oncologist to her surgeon to the oral oncology and maxillofacial prosthetics team, each one of them was familiar with her case and had discussed the best treatment for her squamous cell carcinoma of the premaxilla, a type of oral cancer . (mdanderson.org)
  • All authors are members of the Oral Care Study Group of the Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). (springer.com)
  • The molar ratio of tegafur, gimeracil and oteracil potassium in S-1 is 1.0:0.4:1.0 ( 1 , 2 ). (spandidos-publications.com)
  • a prodrug of 5-fluorouracil) in a 4:1 molar ratio. (aacrjournals.org)
  • Studies have shown that measuring the ratio of these two forms of estrogen, along with other important ratios, provides an important indication of future risk for development of breast cancer. (bountifulbreast.com)
  • S-1 is a fixed combination of tegafur, CDHP, and Oxo at a molar ratio of FT:CDHP:Oxo (1:0.4:1). (aacrjournals.org)
  • TAS-102, a new oral anti-cancer agent composed of a 1:0.5 mixture on a molar ratio of α, α, α-trifluorothymidine (TFD) and a thymidine phosphorylase inhibitor (TPI), tipiracil hydrochloride, has demonstrated improved results in MST and PFS, compared with a placebo, in a global phase 3 trial for metastatic CRC refractory to standard therapies [ 3 ]. (omicsonline.org)
  • Increasing the 599 peptide-to-siRNA molar ratio demonstrated a higher binding capacity for siRNA molecules and enhanced siRNA delivery into the cytoplasm of oral cancer cells. (cylch.org)
  • Oral maxillofacial surgeons typically perform this procedure, though general dentists can also perform them. (colgate.com)
  • Cutting edge information for all oral and maxillofacial surgeons on tissue engineering in maxillofacial reconstruction! (barnesandnoble.com)
  • Mount Sinai's oral and maxillofacial surgeons are skilled in this procedure, which not only replaces missing bone but stimulates new bone growth. (mountsinai.org)
  • We want you to feel comfortable in our office and prepared for your first visit with our oral surgeons. (redondo-oralsurgery.com)
  • Oral and maxillofacial surgeons are different from your family dentist. (oralsurgeonhouston.com)
  • Fusobacteria which are found in the mouth can turn on cancer growth genes to generate colorectal cancer, reveal studies. (medindia.net)
  • The findings could lead to more effective strategies for the early diagnosis, prevention, and treatment of colorectal cancer. (medindia.net)
  • Colorectal cancer is the second leading cause of cancer-related death in the United States. (medindia.net)
  • Recent studies have shown that fusobacteria from the mouth are also abundant in tissues from colorectal cancer patients. (medindia.net)
  • In a mouse model of colorectal cancer, these bacteria accelerated the formation of tumors by attracting immune cells called myeloid cells, which invade tumors and stimulate inflammatory responses that can cause cancer. (medindia.net)
  • Han and her team also found that FadA levels were much higher in tissues from patients with adenomas and colorectal cancer compared with healthy individuals. (medindia.net)
  • Colorectal cancer is a cancer that starts in the colon or the rectum. (medindia.net)
  • Promising results were seen with 5-FU/leucovorin in combination with irinotecan (Camptosar) or oxaliplatin (Eloxatin), especially in colorectal cancer. (cancernetwork.com)
  • Whengiven alone to colorectal cancer patients as a weekly intravenous bolus or for 5consecutive days every 4 to 5 weeks, 5-FU produced response rates ranging from11% to 17% and was associated with a median survival of approximately 1year. (cancernetwork.com)
  • 8] These data correspond with the recent results of arandomized trial conducted by the European Organization for Research andTreatment of Cancer (EORTC-GICCTG) that compared low-dose leucovorin-modulatedbolus 5-FU with a weekly schedule of high-dose infusional 5-FU/leucovorin inpatients with metastatic colorectal cancer. (cancernetwork.com)
  • Thesecombinations proved superior to conventional 5-FU/leucovorin schedules,especially in colorectal cancer. (cancernetwork.com)
  • The mRNA expression levels of enzymes involved in 5‑fluorouracil (5‑FU) metabolism and folate metabolism were measured in formalin‑fixed, paraffin‑embedded tumor sections obtained from the primary tumors of 54 patients with resected stage II or III colorectal cancer who received S‑1 for one year. (spandidos-publications.com)
  • In patients with stage III colorectal cancer, high TP expression was associated with significantly improved outcomes compared with low TP expression (P=0.039). (spandidos-publications.com)
  • Late phase II studies of patients with advanced or recurrent colorectal cancer have reported a response rate of 37.4% in patients with advanced or recurrent colorectal cancer ( 4 , 5 ). (spandidos-publications.com)
  • Together with the results of our previous feasibility study, this suggests that S-1 is a promising drug for adjuvant therapy in patients with stage II or III colorectal cancer ( 7 - 9 ). (spandidos-publications.com)
  • Colorectal cancer is one of the most frequent malignancies in humans and an important cause of cancer death. (scielo.br)
  • Metastatic colorectal cancer remains incurable with available systemic therapeutic options. (scielo.br)
  • Colorectal cancer is one of the most common human malignancies, and is among the leading causes of cancer death (1,2). (scielo.br)
  • Incidence and mortality rates of colorectal cancer in the USA and Western Europe seem to have declined or remained constant over the past ten years (1). (scielo.br)
  • In Brazil, on the other hand, these figures seem to be increasing (2), as suggested by a recent report from the Instituto Nacional de Câncer (2), according to which colorectal carcinoma affects nowadays 30% more Brazilians than in 1989, and kills approximately 40% more cancer patients in our country than ten years ago. (scielo.br)
  • Among these are familial adenomatous polyposis, the hereditary non-polyposis colorectal cancer syndromes, Gardner's syndrome, Turcot's syndrome, and Lynch's syndrome (3). (scielo.br)
  • New drugs have improved the outcome of metastatic colorectal cancer treatment. (omicsonline.org)
  • TAS-102 has proved to be an effective and safe agent for the 3rd or 4th lines of advanced colorectal cancer . (omicsonline.org)
  • Oral contraceptive use cheap date lyrics hormonereplacement therapy, reproductive history and risk of colorectal cancer inwomen. (paperbookintensive.org)
  • He is a practicing dentist and one of the foremost experts in oral-systemic health promotion. (ndnr.com)
  • You see, I am living here in a trailer park … When I was looking for this guy for a dentist, I had cancer. (sun-sentinel.com)
  • Board-certified veterinary dentist Dan Carmichael, who works in the metropolitan New York area, says the best thing you can do to maintain or improve your dog's oral health is to follow the same advice your own dentist gives you: Brush every day. (whole-dog-journal.com)
  • Military Dependents are always welcome at Juliann Lyons, D.D.S.. Denver area dentist Dr. Juliann Lyons welcomes you to her office, and looks forward to ensuring your family's optimal oral health for years to come. (1stpediatricdentist.com)
  • Sealants, Hoak says, are good preventative treatments provided by a dentist, and can start when six year molars grow in. (statecollege.com)
  • It is recommended by the ADA that everyone should visit the dentist at least twice per year to ensure optimal oral health. (southriverperiodontics.com)
  • This must be performed by a dentist or oral surgeon, and usually requires local anesthesia or conscious sedation. (redondo-oralsurgery.com)
  • Please contact us if you have any questions about the different between an oral surgeon and family dentist. (oralsurgeonhouston.com)
  • Dry mouth can accelerate tooth decay and oral infections if not treated properly. (supersmile.com)
  • Common oral sores and infections. (helsinki.fi)
  • Human papillomavirus infections in the oral mucosa. (helsinki.fi)
  • A combination treatment was then evaluated in mice with advanced metastatic disease using a serially selected metastatic variant of the MDA-MB-231 breast cancer-cell line, 231/LM2-4. (aacrjournals.org)
  • e.g., oral cyclophosphamide plus oral methotrexate for the clinical treatment of metastatic breast cancer ( 9 ) or cyclophosphamide and oral etoposide given sequentially, combined with malidomide and celecoxib for clinical treatment of a variety of solid tumor types ( 10 ). (aacrjournals.org)
  • The cardinal features of this model are a simple procedure and a similarity to the metastatic form of human lung cancer. (aacrjournals.org)
  • Trifluridine/tipiracil has recently been granted an additional indication in the USA for the treatment of metastatic gastric cancer, including gastroesophageal junction adenocarcinoma, in patients who have been previously treated with at least two systemic treatment regimens, and has received a positive opinion for this indication in the EU. (springer.com)
  • The aim of treating metastatic gastric cancer is to prolong survival and maximize health-related quality of life (HR-QOL). (springer.com)
  • It has also recently been approved in the USA [ 5 ], and received a positive opinion in the EU [ 9 ], for the treatment of patients with metastatic gastric cancer who have been treated with ≥ 2 prior treatment regimens. (springer.com)
  • We report a retrospective, but relatively contemporary study of 38 cases of metastatic oral tumours in a Canadian population to compare the Canadian experience with that of nearby and distant countries. (jcda.ca)
  • Data about patients' age, sex, site of metastatic deposits, clinical history, including the presence of a known primary cancer, and radiographic features were collected from the files (1992-2010) of the oral pathology diagnostic service at the University of Western Ontario, and the hospital archives (2002-2010) of the department of pathology, London Health Sciences Centre, London, Ontario. (jcda.ca)
  • The relative frequency of types of metastatic cancer to the oral region is similar in Canada, the United States and Northern Europe, but differs significantly from those reported in South East Asia and Japan. (jcda.ca)
  • The actual incidence of these cancers is unknown since oral metastatic disease is usually a manifestation of advanced disease and an unknown number of patients die without investigation for occult oral metastases. (jcda.ca)
  • Most reports of oral metastases involve 1 or 2 case reports from scattered geographical areas, or reviews of these reported cases, 1,2,5 but surprisingly, few series of oral metastatic disease from a given geographic region are reported. (jcda.ca)
  • Because we were unable to find a previous report of a series of metastatic tumours to the oral region in a Canadian population, we report a retrospective, but relatively contemporary study of 38 Canadian cases, and compare this Canadian experience with that of nearby and distant countries. (jcda.ca)
  • Oral inflammation, the body's response to any problem in the mouth, shows up not only in periodontal disease, which, according to the American Academy of Periodontology, afflicts nearly 80% of the US adult population and is the most common inflammatory disease in humans. (ndnr.com)
  • Reverse smoking, in which the lit end of a tobacco cigarette is held in the mouth during inhalation, is also causative of OCSCC, with particular risk of cancer of the hard palate. (ahns.info)
  • You could be eligible for substantial compensation if your doctor misdiagnosed, failed to diagnose, or delayed the diagnosis of cancer inside your mouth, nose, throat, or other areas of your head or neck. (medicalmalpracticehelp.com)
  • According to the National Cancer Institute , cancers of the head and neck include most cancers that form in the squamous cells lining the mouth, nose, and throat. (medicalmalpracticehelp.com)
  • Oral cancers can appear on your lips, gums, and tongue, along the lining of your cheeks and lips, under your tongue, on the roof of your mouth, and even behind your back molars. (medicalmalpracticehelp.com)
  • Cancers can also develop in the saliva-producing glands on the floor of your mouth near your jawbone. (medicalmalpracticehelp.com)
  • Introduction It's estimated that about 40,000 fresh instances and 8 around,000 deaths linked to cancer from the mouth and pharynx will happen annually in america Lacosamide reversible enzyme inhibition in 2012 [1]. (cylch.org)
  • Mouth Aches In The Molars To The Throat? (healthreplies.com)
  • Good afternoon, for 2 days, my mouth ached in the back of the right molars to the throat. (healthreplies.com)
  • A mouth ulcer that does not heal within 3 weeks could be a sign of mouth cancer and needs to be checked by your doctor. (healthnavigator.org.nz)
  • Rarely, ulcers can be a sign of something more serious, such as mouth cancer. (healthnavigator.org.nz)
  • Rarely, this may be a sign of mouth cancer. (healthnavigator.org.nz)
  • If picked up early, mouth cancer can be treated effectively. (healthnavigator.org.nz)
  • Mouth cancer is more likely if you are male, aged 45 years or over, a heavy smoker and/or a heavy drinker. (healthnavigator.org.nz)
  • Oral cancer starts in the cells of the mouth, tongue or throat. (youroralhealth.ca)
  • The types of cancers that most frequently metastasize to the mouth and jaws reflect, for the most part, the relative incidence of cancers in a given population at a given time. (jcda.ca)
  • The relative frequency of types of cancer that metastasize to the mouth and jaws reflects the relative incidence of cancers in the population. (jcda.ca)
  • Carcinomas are the most common types of cancers that metastasize to the mouth and jaws. (jcda.ca)
  • There are antibiotics by mouth (or oral contraceptives for women) and treatments on the skin that can be used to control acne. (docplayer.net)
  • These important ratios also indicate increased long-term risk for other estrogen-sensitive cancers, including uterine, ovarian, cervical, and even head and neck cancers! (bountifulbreast.com)
  • Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and results in more than 200,000 deaths annually in the People's Republic of China. (pnas.org)
  • Oral cancer is one of the ten most common cancers worldwide. (hindawi.com)
  • Plaque is a biofilm, which is made up almost entirely of oral bacteria, contained in a matrix composed of salivary glycoproteins and extracellular polysaccharides. (vin.com)
  • 5] Note that alcohol itself is not carcinogenic but it potentiates the effects of carcinogens by increasing the permeability of the oral mucosa. (wikipedia.org)
  • The lips and the buccal mucosa are the components of the oral vestibule, which plays important roles in oral competence, mastication and speech. (ahns.info)
  • Most metastases were to the mandible, although oral soft tissues were also involved, most frequently, the gingiva and mucosa of the alveolar ridge. (jcda.ca)
  • 1,2 Although the oral soft tissues may be affected, particularly the gingiva and mucosa of the alveolar ridge, and the tongue, metastases to the jaw bones, especially the posterior mandible, are considerably more common. (jcda.ca)
  • There is probably little to no difference in oral health-related quality of life and anxiety in children with carious lesions treated using 3 different strategies. (helsinki.fi)
  • Many family dentists are familiar with some of the above surgical procedures, but only an Oral Surgeon has completed the necessary training and education to put your mind at ease that you are getting the procedure done correctly. (oralsurgeonhouston.com)
  • Your gift will help support our mission to end cancer and make a difference in the lives of our patients. (mdanderson.org)
  • The estimated worldwide incidence of pancreatic cancer was 277,000 cases and an estimated 266,000 patients died from the disease in 20081. (clinicaltrials.gov)
  • In addition to cyclophosphamide, we used UFT, which has been successfully used in metronomic-like dosing regimens (e.g., 250 mg/m 2 daily for two years), for adjuvant treatment of early-stage resected non-small-cell lung cancer patients ( 4 , 12 ). (aacrjournals.org)
  • The purpose of this study is to review the evidence base from 1990 to 2008 to (1) clarify the impact of cancer therapies on prevalence of osteoradionecrosis (ORN) in head and neck cancer patients, and to (2) evaluate management strategies and their consequences on quality of life and cost of care. (springer.com)
  • Dr. Santilli uses advanced non-invasive painless visualization technology to screen all her patients for oral cancer. (380news.com)
  • No possible cause psoriasis, a disorder of the patients blood pressure, cholesterol, and colon cancer. (childbirthsolutions.com)
  • The nose 50mg jelly kamagra oral is in turn increases the patients vital signs. (childbirthsolutions.com)
  • Dr. Kressin is an essential part of our team in treating my patients with cancer. (mypetsdentist.com)
  • Patients may have facial swellings , draining tracts , oral cysts or tissue growths that appear very bad, but they are able to be treated. (mypetsdentist.com)
  • Therefore, suppression of lymphatic metastasis provides an improvement in survival time in lung cancer patients. (aacrjournals.org)
  • To determine the maximum tolerated dose, dose-limiting toxicities(DLTs), and pharmacokinetics of S-1, a combination of tegafur, 5-chloro-2,4-dihydroxypyridine (CDHP), and oxonic acid, administered once daily in patients with advanced cancer. (aacrjournals.org)
  • Information for oral and maxillofacial patients: can it be improved? (kcl.ac.uk)
  • Dr Sindelar has a passion for improving and caring for smiles, as well as helping his patients and the general public understand the important link between oral health, cardiovascular disease risk, and overall well-being. (ndnr.com)
  • Unfortunately, doctors occasionally fail to screen for cancer when patients come to them with persistent throat pain or discomfort. (medicalmalpracticehelp.com)
  • Treatment of medically compromised patients, including organ transplant patients and pre and post-surgical radiation oral cancer patients. (huhealthcare.com)
  • Studies also have shown that cancer patients tend to have lower levels of Vitamin C than generally healthy people. (cancertutor.com)
  • Nonetheless, because of Vitamin C's supportive functions in the body, increasing the Vitamin C status of cancer patients is likely to be of benefit. (cancertutor.com)
  • 4. Since cancer patients are often depleted of Vitamin C, replenishment may improve immune system function and enhance patient health and well-being. (cancertutor.com)
  • The study by Pauling and Cameron suggested that Vitamin C, given by I.V., could extend the life of advanced cancer patients by as much as six times the estimated prognosis. (cancertutor.com)
  • Known cases involve patients who develop symptomatic oral metastases while they are still alive. (jcda.ca)
  • In line with the published data, adjuvant S-1 therapy has a tolerable toxicity profile among local patients who have undergone curative resection for gastric cancer. (hkmj.org)
  • For gastric cancer patients in whom adjuvant S-1 therapy is planned, close monitoring of those who have identifiable risk factors may enable early recognition of adverse events during therapy. (hkmj.org)
  • Many patients who receive radiation therapy for cancers of the head and neck develop chemosensory disorders. (masseyeandear.org)
  • Researchers who study plaque know that many different types of oral bacteria stick to each other in test-tube experiments. (clinicaltrials.gov)
  • When the bacteria was treated or the tooth removed, the cancer disappeared in 30 days. (bountifulbreast.com)
  • This local inflammatory process may induce a systemic inflammatory state through mechanisms that include dissemination of pro-inflammatory cytokine and/or bacteria from the oral to extra-oral sites ( Hajishengallis, 2015 ). (frontiersin.org)
  • Composite fillings (tooth-colored fillings) can now be placed in the back molar areas when tooth decay is detected. (1stcosmeticdentist.com)
  • This article is intended to promote understanding of and knowledge about general oral health topics. (colgate.com)
  • Conceivably, it would be possible to remove the molar of anyone and compare their health to the evidence in the tooth. (dental-tribune.com)
  • Fusobacteria may provide not only a new way to group or describe colon cancers but also, more importantly, a new perspective on how to target pathways to halt tumor growth and spread," senior study author Wendy Garrett of the Harvard School of Public Health and the Dana-Farber Cancer Institute, said. (medindia.net)
  • Katsura K, Sasai K, Sato K, Saito M, Hoshina H, Hayashi T (2008) Relationship between oral health status and development of osteoradionecrosis of the mandible: a retrospective longitudinal study. (springer.com)
  • National Institutes of Health (1990) Consensus development conference on oral complications of cancer therapies: diagnosis, prevention, and treatment. (springer.com)
  • National Institutes of Health (2009) Oral complications of emerging cancer therapies. (springer.com)
  • Oral Health in America: A Report of the Surgeon General (the Report) alerted Americans to the importance of oral health in their daily lives [USDHHS 2000a]. (cdc.gov)
  • Issued in May 2000, the report further detailed how oral health is promoted, how oral diseases and conditions are prevented and managed, and what needs and opportunities exist to enhance oral health. (cdc.gov)
  • The report's message was that oral health is essential to general health and well-being and can be achieved. (cdc.gov)
  • However, several barriers hinder the ability of some Americans to attain optimal oral health. (cdc.gov)
  • The Surgeon General's report concluded with a framework for action, calling for a national oral health plan to improve quality of life and eliminate oral health disparities. (cdc.gov)
  • One component of an oral health plan is a set of measurable and achievable objectives on key indicators of oral disease burden, oral health promotion, and oral disease prevention. (cdc.gov)
  • Included are objectives for key structures, processes, and outcomes related to improving oral health. (cdc.gov)
  • These objectives represent the ideas and expertise of a diverse range of individuals and organizations concerned about the nation's oral health. (cdc.gov)
  • The Surgeon General's report on oral health was a wake-up call, spurring policy makers, community leaders, private industry, health professionals, the media, and the public to affirm that oral health is essential to general health and well-being and to take action. (cdc.gov)
  • That call to action led a broad coalition of public and private organizations and individuals to generate A National Call to Action to Promote Oral Health [USDHHS 2003]. (cdc.gov)
  • The vision of the Call to Action is 'To advance the general health and well-being of all Americans by creating critical partnerships at all levels of society to engage in programs to promote oral health and prevent disease. (cdc.gov)
  • National objectives on oral health such as those in Healthy People 2010 provide measurable targets for the nation, but most core public health functions of assessment, assurance, and policy development occur at the state level. (cdc.gov)
  • The National Call to Action to Promote Oral Health calls for the development of plans at the state and community levels, with attention to planning, evaluation, and accountability [USDHHS 2003]. (cdc.gov)
  • In undertaking this task, the committee reviewed information on the health status of the U.S. population, including data on trends and differences across population subgroups, and evaluated the recommendations of other groups whose primary task was to articulate goals for oral health. (nap.edu)
  • A background paper on oral health status by White et al. (nap.edu)
  • The data on oral health status and services reviewed by this committee came from three primary sources. (nap.edu)
  • The first survey (then called the Health Examination Survey), which took place between 1959 and 1962, included some measures of oral health status as did the second survey conducted from 1971 to 1974. (nap.edu)
  • provides a more extensive discussion of oral health status and trends. (nap.edu)
  • As suggested in this review of sources, the collection of data on oral health status has been somewhat less regular and frequent than the collection of information about many other health problems. (nap.edu)
  • We're committed to helping you have a lifetime of oral health. (1stdentist.com)
  • We're committed to helping you maintain your life-long oral health. (1stwisdomteeth.com)
  • Your comfort and long-term oral health are our first concerns. (1stwisdomteeth.com)
  • He is a co-founder, recent president, and current board member of the American Academy for Oral Systemic Health (www.AAOSH.org). (ndnr.com)
  • A passionate advocate of oral-systemic health, he has developed online video educational systems on adopting an oral-systemic training for healthcare professionals. (ndnr.com)
  • He is the author of Refresh Life , a book on the importance of oral health on overall health and well-being, and is regularly interviewed by local and national radio shows and print news outlets. (ndnr.com)
  • Until recently, oral care was perceived as being a long-term health problem with very little cost to putting it off for the short term. (ndnr.com)
  • It is bringing to light an indisputable truth: oral health has become a necessary and integral part of preventive cardiology, a substantial adjunct to diabetic care, and a major part of the prevention of any inflammatory disease. (ndnr.com)
  • Oral health belongs alongside diet and nutrition, physical activity, stress management, tobacco cessation, and sleep as a pillar of wellness because, like these essential aspects of health, it plays a large part in the prevention and management of these chronic conditions. (ndnr.com)
  • They may just be focused on the basics-food, heating-and education about their oral health may take a back seat. (adea.org)
  • We're committed to making your oral health a reality. (1stpediatricdentist.com)
  • In recent years he has run a programme providing oral health advice and oral cancer awareness for school children featured on Plymouth radio and BBC Spotlight. (plymouthhospitals.nhs.uk)
  • The changing oral health care needs of older adults. (helsinki.fi)
  • A six-month cleaning and check-up improve not just your oral health, but your overall health as well. (tuscfamilydental.com)
  • A panoramic x-ray can reveal a multitude of issues, some not necessarily related to your immediate oral health. (tuscfamilydental.com)
  • This objective is tracked with the DMF and df indexes, which specifications for objectives in Priority Area 13: Oral Health, respectively provide the sum of decayed (D), missing (M), one of 22 priority areas of Healthy People 2000 . (cdc.gov)
  • Oral Health School a. (cdc.gov)
  • You deserve a lifetime of better oral health. (losangeleswisdomteeth.com)
  • In fact, an Oral Surgeon is the only health care specialists, besides an anesthesiologist, who is authorized to administer all levels of sedation, including general anesthesia. (oralsurgeonhouston.com)
  • Does Good Oral Health Help to Prevent Heart Disease? (oralsurgeonhouston.com)
  • Gastric cancer is the second most common cause of cancer-related mortality worldwide, with 988 000 new cases and 736 000 deaths per year. (hkmj.org)
  • Articles were selected for the time period beginning after 1989, excluding the 1990 NCI monograph articles from the 1989 NIH-sponsored Oral Complications in Cancer Therapy Symposium that was published in 1990. (springer.com)
  • Brennan MT, Elting LS, Spijkervet FK (2010) Systematic reviews of oral complications from cancer therapies, Oral Care Study Group, MASCC/ISOO: methodology and quality of the literature. (springer.com)
  • These oral cancer complications significantly decrease quality of life and can lead to serious systemic problems, complications, septicemia, eating difficulty, nutritional deficiencies, and dehydration. (1stdentist.com)
  • Women who have a hydatidiform mole, or molar pregnancy, are at a higher risk of having another one or having another type of GTD. (cancer.ca)
  • In addition to addressing short-term pain relief, focusing on big-picture oral care will help your child develop healthy molars and habits well into adulthood. (colgate.com)
  • Identifying and eliminating bad oral habits is the key to retaining a great smile for many years. (1stcosmeticdentist.com)
  • New cancer treatment modalities such as IMRT and concomitant CRT have had minimal effect on prevalence of ORN. (springer.com)
  • Prevalence of molar-incisor hypomineralization and other enamel defects and associated sociodemographic determinants in Indiana. (helsinki.fi)
  • Classic wound closure following removal of impacted this molars involved the surgeon covering and hermitically closes the socket with a flap, allowing primary wound healing. (nationalelfservice.net)
  • I had a chipped left molar in July of 2015 that was cutting the left side of my tongue. (caringbridge.org)
  • The biopsy came back positive for squamous cell carcinoma (skin cancer) of the tongue. (caringbridge.org)
  • As his term as Niels Bohr Professor draws to a close in 2018, Needham is now bringing his new approach to anti-cancer diapeutics home to the Duke Cancer Institute for testing. (duke.edu)
  • April 3, 2008 -- Overweight children might be at an elevated risk for many diseases, but oral disease isn't one of them. (drbicuspid.com)
  • Oral inflammation results in an inflammatory response, the byproducts of which can and do spread throughout the body to influence all inflammatory diseases found in human beings - the major inflammatory ones being heart disease and diabetes. (ndnr.com)
  • RNA interference (RNAi) appears to be a promising therapeutic tool for the treatment of many diseases, including oral cancer. (cylch.org)
  • Free radicals may play a part in cancer, heart disease, stroke, and other diseases of aging. (cancertutor.com)
  • Loneliness and disability as predictors of oral diseases among 2 groups of older adults in central India. (helsinki.fi)
  • Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of mediators of inflammation into the blood circulation, which may contribute to exacerbate several diseases. (frontiersin.org)
  • I've noticed a couple more small spots in the same area in the last couple weeks.We are now working with the Head and Neck Cancer team at the Levine Cancer Institute in Charlotte who have wonderful so far. (caringbridge.org)
  • Head and neck cancer has been known to physicians since antiquity, hut until relatively recently any material advance was limited by the lack of anaesthesia. (kcl.ac.uk)
  • You could be eligible for substantial compensation if you or a loved one suffered harm because a doctor misdiagnosed head or neck cancer. (medicalmalpracticehelp.com)
  • A head or neck cancer misdiagnosis can be considered medical malpractice . (medicalmalpracticehelp.com)
  • A head and neck cancer misdiagnosis lawyer can help you take the legal steps necessary to recover damages . (medicalmalpracticehelp.com)
  • If you or your loved one suffered injury or death because of a doctor's failure to properly diagnose head or neck cancer, the medical malpractice lawyers at Medical Malpractice Help want to help you pursue the fair compensation you deserve. (medicalmalpracticehelp.com)
  • Cancers of the head and neck include the following. (medicalmalpracticehelp.com)
  • When a patient visits a doctor with symptoms affecting the head or neck, the doctor should never rule out cancer as a possibility, even if the odds usually tilt toward another diagnosis. (medicalmalpracticehelp.com)
  • A doctor presented with one or more of the above symptoms has a duty to take immediate steps to rule out head or neck cancer. (medicalmalpracticehelp.com)
  • In addition to screening for symptoms, a doctor should be on high alert for head and neck cancer when a patient has one or more risk factors that elevate their chances of developing it. (medicalmalpracticehelp.com)
  • General information includes use of alcohol or tobacco, both major risk factors for head and neck cancer, and systemic symptoms, such as fever and weight loss. (berlin-klinik.com)
  • Head and Neck Cancer Quality Improvement and Audit. (plymouthhospitals.nhs.uk)
  • In a 5-year study, 93% of women with breast cancer were found to have root canals and 7% had oral pathologies. (bountifulbreast.com)
  • The use of 5-FU prodrugs such as tegafur, with increased bioavailability, can facilitate chronic oral administration of fluoropyrimidines. (aacrjournals.org)
  • S-1 is an oral fluorinated pyrimidine combination, developed in an effort to further enhance the therapeutic index of tegafur. (aacrjournals.org)
  • Some of these series are small and outdated 6,7 and because of changes in the incidence and mortality of cancer types over time in a population, 8 they are not useful for a contemporary comparison of data. (jcda.ca)
  • Even more recently published series from the United States 9,10 and Europe, 11 and a review of the Japanese literature 12 include cases from distant decades that skew their data because of contemporary shifts in the incidence of various cancers. (jcda.ca)
  • If left untreated, however, oral cancers can spread to nearby tissues and bones, making the treatment needed to remove them much more invasive, painful, and potentially dangerous. (medicalmalpracticehelp.com)
  • Squamous cell cancers can develop on the tissues lining the pharynx. (medicalmalpracticehelp.com)
  • HPV+ cancers have a better prognosis than HPV- ones. (coursehero.com)
  • It is not possible to look at or to touch an oral mas and determine the diagnosis, prognosis or an appropriate treatment plan. (mypetsdentist.com)
  • The biology and prognosis of oral tumors are well understood. (mypetsdentist.com)
  • The extent of lymphatic metastasis is the most important factor in the prognosis for non-small cell lung cancer (NSCLC). (aacrjournals.org)
  • 3 Oral metastasis carries a grave prognosis for the patient because it represents advanced disease. (jcda.ca)
  • The development of early metastases is typical for oral cancer, and increased MMP-9 expression is associated with a poor disease prognosis. (hindawi.com)
  • Procedures including those listed below are performed by an Oral Maxillofacial Surgeon. (oralsurgeonhouston.com)
  • Previous studies have also demonstrated that enterokinase, a membrane-bound serine protease, cleaves proMMP-9 at Lys 65 -Ser 66 [ 13 ] and that trypsin-2 activates proMMP-9 at very low molar ratios, 1 : 1000. (hindawi.com)
  • As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. (mdanderson.org)
  • Oral candidiasis, herpes zoster and oral hair leukoplakia are clinical features of which disease? (coursehero.com)
  • Recent clinical studies revealed that some molecules, such as metalloproteinase-2 (2 , 3) , CD44 variant 6 (4 , 5) , and vascular endothelial growth factor-C (6 , 7) , are related to lymphatic metastasis in primary cancer. (aacrjournals.org)
  • 5. High dose IVC is a chemotherapeutic agent that can be given in conjunction with conventional cancer treatments. (cancertutor.com)
  • The research center Needham created has as its primary goal developing novel strategies using micro- and nano- technology to improve drug delivery, specifically for cancer treatments. (duke.edu)
  • Why is Oral hygiene and Preventive care in Seniors important? (medindia.net)