AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceHealth Care
OphthalmoplegiaOphthalmoplegia, Chronic Progressive ExternalKearns-Sayre SyndromeMiller Fisher SyndromeBlepharoptosisOcular Motility DisordersAnisocoriaDNA, MitochondrialCavernous SinusHerpes Zoster OphthalmicusExophthalmosOculomotor MusclesTolosa-Hunt SyndromeDiplopiaOculomotor Nerve DiseasesMitochondrial MyopathiesMitochondrial DiseasesWernicke EncephalopathyMitochondrial EncephalomyopathiesAbducens NerveAbducens Nerve DiseasesAdenine Nucleotide Translocator 1Cranial Nerve DiseasesAtaxiaOculomotor NerveNystagmus, PathologicMuscular DiseasesOrbital NeoplasmsDiffuse Cerebral Sclerosis of SchilderOrbital PseudotumorMitochondria, MuscleIntestinal Pseudo-ObstructionElectrooculographyNeuromuscular DiseasesEye MovementsGangliosidesOrbitSyndromeFacial ParalysisPonsTrochlear Nerve DiseasesMyelitis, TransverseMagnetic Resonance ImagingDNA-Directed DNA PolymeraseOrbital DiseasesGuillain-Barre SyndromeParanasal Sinus DiseasesCerebellar AtaxiaPrednisoloneFatal OutcomeMyasthenia Gravis
Ophthalmoplegia
Paralysis of one or more of the ocular muscles due to disorders of the eye muscles, neuromuscular junction, supporting soft tissue, tendons, or innervation to the muscles.
Ophthalmoplegia, Chronic Progressive External
A mitochondrial myopathy characterized by slowly progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. Ragged-red fibers and atrophy are found on muscle biopsy. Familial and sporadic forms may occur. Disease onset is usually in the first or second decade of life, and the illness slowly progresses until usually all ocular motility is lost. (From Adams et al., Principles of Neurology, 6th ed, p1422)
Kearns-Sayre Syndrome
A mitochondrial disorder featuring the triad of chronic progressive EXTERNAL OPHTHALMOPLEGIA, cardiomyopathy (CARDIOMYOPATHIES) with conduction block (HEART BLOCK), and RETINITIS PIGMENTOSA. Disease onset is in the first or second decade. Elevated CSF protein, sensorineural deafness, seizures, and pyramidal signs may also be present. Ragged-red fibers are found on muscle biopsy. (Adams et al., Principles of Neurology, 6th ed, p984)
Miller Fisher Syndrome
A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)
Blepharoptosis
Drooping of the upper lid due to deficient development or paralysis of the levator palpebrae muscle.
Ocular Motility Disorders
Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)
Anisocoria
Unequal pupil size, which may represent a benign physiologic variant or a manifestation of disease. Pathologic anisocoria reflects an abnormality in the musculature of the iris (IRIS DISEASES) or in the parasympathetic or sympathetic pathways that innervate the pupil. Physiologic anisocoria refers to an asymmetry of pupil diameter, usually less than 2mm, that is not associated with disease.
DNA, Mitochondrial
Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins.
Cavernous Sinus
An irregularly shaped venous space in the dura mater at either side of the sphenoid bone.
Herpes Zoster Ophthalmicus
Virus infection of the Gasserian ganglion and its nerve branches characterized by pain and vesicular eruptions with much swelling. Ocular involvement is usually heralded by a vesicle on the tip of the nose. This area is innervated by the nasociliary nerve.
Exophthalmos
Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
Oculomotor Muscles
The muscles that move the eye. Included in this group are the medial rectus, lateral rectus, superior rectus, inferior rectus, inferior oblique, superior oblique, musculus orbitalis, and levator palpebrae superioris.
Tolosa-Hunt Syndrome
An idiopathic syndrome characterized by the formation of granulation tissue in the anterior cavernous sinus or superior orbital fissure, producing a painful ophthalmoplegia. (Adams et al., Principles of Neurology, 6th ed, p271)
Diplopia
A visual symptom in which a single object is perceived by the visual cortex as two objects rather than one. Disorders associated with this condition include REFRACTIVE ERRORS; STRABISMUS; OCULOMOTOR NERVE DISEASES; TROCHLEAR NERVE DISEASES; ABDUCENS NERVE DISEASES; and diseases of the BRAIN STEM and OCCIPITAL LOBE.
Oculomotor Nerve Diseases
Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)
Mitochondrial Myopathies
A group of muscle diseases associated with abnormal mitochondria function.
Mitochondrial Diseases
Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
Wernicke Encephalopathy
An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3)
Mitochondrial Encephalomyopathies
A heterogenous group of disorders characterized by alterations of mitochondrial metabolism that result in muscle and nervous system dysfunction. These are often multisystemic and vary considerably in age at onset (usually in the first or second decade of life), distribution of affected muscles, severity, and course. (From Adams et al., Principles of Neurology, 6th ed, pp984-5)
Abducens Nerve
The 6th cranial nerve which originates in the ABDUCENS NUCLEUS of the PONS and sends motor fibers to the lateral rectus muscles of the EYE. Damage to the nerve or its nucleus disrupts horizontal eye movement control.
Abducens Nerve Diseases
Diseases of the sixth cranial (abducens) nerve or its nucleus in the pons. The nerve may be injured along its course in the pons, intracranially as it travels along the base of the brain, in the cavernous sinus, or at the level of superior orbital fissure or orbit. Dysfunction of the nerve causes lateral rectus muscle weakness, resulting in horizontal diplopia that is maximal when the affected eye is abducted and ESOTROPIA. Common conditions associated with nerve injury include INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; ISCHEMIA; and INFRATENTORIAL NEOPLASMS.
Adenine Nucleotide Translocator 1
A subtype of mitochondrial ADP, ATP translocase found primarily in heart muscle (MYOCARDIUM) and skeletal muscle (MUSCLE, SKELETAL).
Cranial Nerve Diseases
Disorders of one or more of the twelve cranial nerves. With the exception of the optic and olfactory nerves, this includes disorders of the brain stem nuclei from which the cranial nerves originate or terminate.
Ataxia
Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Oculomotor Nerve
The 3d cranial nerve. The oculomotor nerve sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye. It also sends parasympathetic efferents (via the ciliary ganglion) to the muscles controlling pupillary constriction and accommodation. The motor fibers originate in the oculomotor nuclei of the midbrain.
Nystagmus, Pathologic
Involuntary movements of the eye that are divided into two types, jerk and pendular. Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (Adams et al., Principles of Neurology, 6th ed, p272)
Muscular Diseases
Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
Orbital Neoplasms
Neoplasms of the bony orbit and contents except the eyeball.
Diffuse Cerebral Sclerosis of Schilder
A rare central nervous system demyelinating condition affecting children and young adults. Pathologic findings include a large, sharply defined, asymmetric focus of myelin destruction that may involve an entire lobe or cerebral hemisphere. The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. Concentric sclerosis of Balo is differentiated from diffuse cerebral sclerosis of Schilder by the pathologic finding of alternating bands of destruction and preservation of myelin in concentric rings. Alpers' Syndrome refers to a heterogeneous group of diseases that feature progressive cerebral deterioration and liver disease. (From Adams et al., Principles of Neurology, 6th ed, p914; Dev Neurosci 1991;13(4-5):267-73)
Orbital Pseudotumor
A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).
Mitochondria, Muscle
Mitochondria of skeletal and smooth muscle. It does not include myocardial mitochondria for which MITOCHONDRIA, HEART is available.
Intestinal Pseudo-Obstruction
A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.
Electrooculography
Recording of the average amplitude of the resting potential arising between the cornea and the retina in light and dark adaptation as the eyes turn a standard distance to the right and the left. The increase in potential with light adaptation is used to evaluate the condition of the retinal pigment epithelium.
Neuromuscular Diseases
A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
Eye Movements
Voluntary or reflex-controlled movements of the eye.
Gangliosides
A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)
Orbit
Bony cavity that holds the eyeball and its associated tissues and appendages.
Syndrome
A characteristic symptom complex.
Facial Paralysis
Severe or complete loss of facial muscle motor function. This condition may result from central or peripheral lesions. Damage to CNS motor pathways from the cerebral cortex to the facial nuclei in the pons leads to facial weakness that generally spares the forehead muscles. FACIAL NERVE DISEASES generally results in generalized hemifacial weakness. NEUROMUSCULAR JUNCTION DISEASES and MUSCULAR DISEASES may also cause facial paralysis or paresis.
Pons
The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.
Trochlear Nerve Diseases
Diseases of the fourth cranial (trochlear) nerve or its nucleus in the midbrain. The nerve crosses as it exits the midbrain dorsally and may be injured along its course through the intracranial space, cavernous sinus, superior orbital fissure, or orbit. Clinical manifestations include weakness of the superior oblique muscle which causes vertical DIPLOPIA that is maximal when the affected eye is adducted and directed inferiorly. Head tilt may be seen as a compensatory mechanism for diplopia and rotation of the visual axis. Common etiologies include CRANIOCEREBRAL TRAUMA and INFRATENTORIAL NEOPLASMS.
Myelitis, Transverse
Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)
Magnetic Resonance Imaging
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
DNA-Directed DNA Polymerase
DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
Orbital Diseases
Diseases of the bony orbit and contents except the eyeball.
Guillain-Barre Syndrome
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Paranasal Sinus Diseases
Diseases affecting or involving the PARANASAL SINUSES and generally manifesting as inflammation, abscesses, cysts, or tumors.
Cerebellar Ataxia
Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
Prednisolone
A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
Fatal Outcome
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Myasthenia Gravis
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)

Absent pituitary gland and hypoplasia of the cerebellar vermis associated with partial ophthalmoplegia and postaxial polydactyly: a variant of orofaciodigital syndrome VI or a new syndrome? (1/328)

We report two sibs with features overlapping those of orofaciodigital syndrome type VI (Varadi syndrome). Both presented at birth with oculomotor abnormalities, dysmorphic facial features, and dysgenesis of the cerebellar vermis. There were minimal oral manifestations (high arched palate) in both of them and one had postaxial polydactyly of both hands and one foot. In addition, there was evidence of aplasia of the pituitary gland on MRI scan in both of them with evidence of hypopituitarism. Both responded well to hormone replacement therapy with improvement in their linear growth and mental ability. These cases may represent a new autosomal recessive midline defect syndrome with features overlapping OFDS VI. Alternatively the features in these children could represent variability within OFDS VI.  (+info)

Congenital myasthenia gravis: clinical and HLA studies in two brothers. (2/328)

Two brothers with congenital myasthenia gravis are described. In both, ptosis and ophthalmoplegia responded poorly to oral anticholinesterase therapy and to thymectomy. The brothers had two different HLA haplotypes and neither had the HLA-A1-B8-DW3 haplotypes which are commonly associated with myathenia gravis in adult-onset cases.  (+info)

Dominant hereditary inclusion-body myopathy gene (IBM3) maps to chromosome region 17p13.1. (3/328)

We recently described an autosomal dominant inclusion-body myopathy characterized by congenital joint contractures, external ophthalmoplegia, and predominantly proximal muscle weakness. A whole-genome scan, performed with 161 polymorphic markers and with DNA from 40 members of one family, indicated strong linkage for markers on chromosome 17p. After analyses with additional markers in the region and with DNA from eight additional family members, a maximum LOD score (Zmax) was detected for marker D17S1303 (Zmax=7.38; recombination fraction (theta)=0). Haplotype analyses showed that the locus (Genome Database locus name: IBM3) is flanked distally by marker D17S945 and proximally by marker D17S969. The positions of cytogenetically localized flanking markers suggest that the location of the IBM3 gene is in chromosome region 17p13.1. Radiation hybrid mapping showed that IBM3 is located in a 2-Mb chromosomal region and that the myosin heavy-chain (MHC) gene cluster, consisting of at least six genes, co-localizes to the same region. This localization raises the possibility that one of the MHC genes clustered in this region may be involved in this disorder.  (+info)

Tolosa Hunt syndrome: a case report. Clinical and magnetic resonance imaging findings. (4/328)

A 36-year-old woman was admitted with a left abducens nerve palsy. MR showed enlargement of the left cavernous sinus. The patient was treated with 80 mg oral methyl prednisolone. Clinical findings improved within a month. Two months later, she was readmitted with left oculomotor and right abducens nerve palsy. MR showed significant increase in the volume of the abnormal area in the left cavernous sinus and a new lesion within the right cavernous sinus. After intravenous gadolinium DTPA, there was enhancement in both cavernous sinuses. Methyl prednisolone therapy was again started. After one month of treatment neurological examination was normal. Follow-up MR findings were similar to previous ones.  (+info)

Clinical genetics of familial progressive supranuclear palsy. (5/328)

Recent studies have shown that progressive supranuclear palsy (PSP) could be inherited, but the pattern of inheritance and the spectrum of the clinical findings in relatives are unknown. We here report 12 pedigrees, confirmed by pathology in four probands, with familial PSP. Pathological diagnosis was confirmed according to recently reported internationally agreed criteria. The spectrum of the clinical phenotypes in these families was variable including 34 typical cases of PSP (12 probands plus 22 secondary cases), three patients with postural tremor, three with dementia, one with parkinsonism, two with tremor, dystonia, gaze palsy and tics, and one with gait disturbance. The presence of affected members in at least two generations in eight of the families and the absence of consanguinity suggests autosomal dominant transmission with incomplete penetrance. We conclude that hereditary PSP is more frequent than previously thought and that the scarcity of familial cases may be related to a lack of recognition of the variable phenotypic expression of the disease.  (+info)

CFEOM3: a new extraocular congenital fibrosis syndrome that maps to 16q24.2-q24.3. (6/328)

PURPOSE: To define the clinical characteristics and determine the gene localization for a previously undescribed form of congenital fibrosis of the extraocular muscles (CFEOM), referred to as CFEOM type 3 (CFEOM3). METHODS: A large family with CFEOM was identified, and participating individuals underwent ophthalmologic examination and donated blood for genetic analysis. The family's disorder was tested for linkage to the known CFEOM loci, followed by a genome-wide search and linkage refinement using polymorphic DNA markers. RESULTS: Thirty-eight members of this Canadian family participated in the study. Affected individuals are born with a nonprogressive eye movement disorder characterized by variable expression of ptosis and restrictive external ophthalmoplegia. Severely affected individuals have ptosis, primary gaze fixed in a hypo- and exotropic position, and marked restriction of eye movement bilaterally. Mildly affected individuals have normally positioned globes with a limitation of vertical gaze. Moderately affected individuals have asymmetrical involvement with one eye severely and one eye mildly affected. The disorder is autosomal dominant with variable expression and probable incomplete penetrance. Genetic analysis reveals linkage to markers on 16q24.2q24.3. A maximum lod score of 5.8 occurs at markers D16S3063 and D16S689, and the CFEOM3 disease gene is located within a 5.6-cM region flanked by D16S486 and D16S671. CONCLUSIONS: These data establish that CFEOM3 is a phenotypically variant and genotypically distinct form of CFEOM with linkage to chromosome 16qter. The authors have previously demonstrated that CFEOM1 results from a developmental absence of the superior division of the oculomotor nerve. The authors hypothesize that CFEOM3 results from a defect analogous to, but distinct from CFEOM1.  (+info)

Neuro-Behcet's disease presenting with isolated unilateral lateral rectus muscle palsy. (7/328)

The authors present the clinical findings of a 30-year-old female and a 29-year-old male who both had isolated unilateral lateral rectus muscle palsy in neuro-Behcet's disease. The clinical feature related to isolated abduscens nerve palsy was identified by CT, systemic assessment and extraocular examination. These patients' constellation of findings appear to be unique: it does not follow any previously reported pattern of ocular manifestations of neuro-Behcet's disease.  (+info)

Proprioceptive and retinal afference modify postsaccadic ocular drift. (8/328)

Drift of the eyes after saccades produces motion of images on the retina (retinal slip) that degrades visual acuity. In this study, we examined the contributions of proprioceptive and retinal afference to the suppression of postsaccadic drift induced by a unilateral ocular muscle paresis. Eye movements were recorded in three rhesus monkeys with a unilateral weakness of one vertical extraocular muscle before and after proprioceptive deafferentation of the paretic eye. Postsaccadic drift was examined in four visual states: monocular viewing with the normal eye (4-wk period); binocular viewing (2-wk period); binocular viewing with a disparity-reducing prism (2-wk period); and monocular viewing with the paretic eye (2-wk period). The muscle paresis produced vertical postsaccadic drift in the paretic eye, and this drift was suppressed in the binocular viewing condition even when the animals could not fuse. When the animals viewed binocularly with a disparity-reducing prism, the drift in the paretic eye was suppressed in two monkeys (with superior oblique pareses) but generally was enhanced in one animal (with a tenotomy of the inferior rectus). When drift movements were enhanced, they reduced the retinal disparity that was present at the end of the saccade. In the paretic-eye-viewing condition, postsaccadic drift was suppressed in the paretic eye and was induced in the normal eye. After deafferentation in the normal-eye-viewing state, there was a change in the vertical postsaccadic drift of the paretic eye. This change in drift was idiosyncratic and variably affected the amplitude and velocity of the postsaccadic drift movements of the paretic eye. Deafferentation of the paretic eye did not affect the postsaccadic drift of the normal eye nor did it impair visually mediated adaptation of postsaccadic drift. The results demonstrate several new findings concerning the roles of visual and proprioceptive afference in the control of postsaccadic drift: disconjugate adaptation of postsaccadic drift does not require binocular fusion; slow, postsaccadic drift movements that reduce retinal disparity but concurrently increase retinal slip can be induced in the binocular viewing state; postsaccadic drift is modified by proprioception from the extraocular muscles, but these modifications do not serve to minimize retinal slip or to correct errors in saccade amplitude; and visually mediated adaptation of postsaccadic drift does not require proprioceptive afference from the paretic eye.  (+info)

Ophthalmoplegia totalis | Article about ophthalmoplegia totalis by The Free DictionaryOphthalmoplegia totalis | Article about ophthalmoplegia totalis by The Free Dictionary
Looking for ophthalmoplegia totalis? Find out information about ophthalmoplegia totalis. a paralysis of one or more cranial nerves by which the eye muscles are innervated. Ophthalmoplegia may be congenital-a result of underdevelopment of the... Explanation of ophthalmoplegia totalis
https://encyclopedia2.thefreedictionary.com/ophthalmoplegia+totalis
Subacute complete ophthalmoplegia: an anti-Hu paraneoplastic m...Subacute complete ophthalmoplegia: an anti-Hu paraneoplastic m...
Subacute complete ophthalmoplegia: an anti-Hu paraneoplastic manifestation of myxoid liposarcoma.: Paraneoplastic neurological syndromes are well-known sequelae
https://www.mysciencework.com/publication/show/subacute-complete-ophthalmoplegia-anti-hu-paraneoplastic-manifestation-myxoid-liposarcoma-c4b323f4
Transorbital intracavernous needle biopsy in painful ophthalmoplegia.<...Transorbital intracavernous needle biopsy in painful ophthalmoplegia.<...
TY - JOUR. T1 - Transorbital intracavernous needle biopsy in painful ophthalmoplegia.. AU - Slamovits, T. L.. PY - 1985/12/1. Y1 - 1985/12/1. UR - http://www.scopus.com/inward/record.url?scp=0022230253&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0022230253&partnerID=8YFLogxK. M3 - Letter. C2 - 4056919. AN - SCOPUS:0022230253. VL - 63. SP - 996. EP - 997. JO - Journal of Neurosurgery. JF - Journal of Neurosurgery. SN - 0022-3085. IS - 6. ER - ...
https://einstein.pure.elsevier.com/en/publications/transorbital-intracavernous-needle-biopsy-in-painful-ophthalmople-2
Painful Ophthalmoplegia & Transient Ischemic Attack<...Painful Ophthalmoplegia & Transient Ischemic Attack<...
Painful Ophthalmoplegia & Transient Ischemic Attack Symptom Checker: Possible causes include Migraine & Cavernous Sinus Aneurysm & Temporal Arteritis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
https://www.symptoma.com/en/ddx/painful-ophthalmoplegia+transient-ischemic-attack
Ischaemic optic neuropathy with painful ophthalmoplegia in diabetes mellitus.
Two patients with mild, adult-onset diabetes mellitus developed a painful ophthalmoplegia and ipsilateral optic neuropathy that was relatively unresponsive to steroids. Histopathological study of the optic nerve of one patient revealed an extensive i
http://www.biomedsearch.com/nih/Ischaemic-optic-neuropathy-with-painful/7317318.html
Ophthalmoparesis - WikipediaOphthalmoparesis - Wikipedia
Neuro-ophthalmologic examination showing ophthalmoplegia affecting the left eye in a patient with Tolosa-Hunt syndrome. The central image represents forward gaze, and each image around it represents gaze in that direction (for example, in the upper left image, the patient looks up and right; the left eye is unable to accomplish this movement). The examination shows ptosis of the left eyelid, exotropia (outward deviation) of the primary look of the left eye, and paresis (weakness) of the third (oculomotor), fourth (trochlear) and sixth (abducens) left cranial nerves ...
https://en.wikipedia.org/wiki/Ophthalmoplegia
A Case of Internal Ophthalmoplegia Associated With Varicella ZosterA Case of Internal Ophthalmoplegia Associated With Varicella Zoster
Journal of Pediatric Ophthalmology and Strabismus | The authors report a case of internal ophthalmoplegia in a 5-year-old boy presenting after primary varicella infection. This is an uncommon and mostly irreversible ocular manifestation after chickenpox. The internal ophthalmoplegia showed a potential mild improvement with oral acyclovir. Consideration should be given to starting treatment on presentation in such cases.From NHS Eye Clinic,
https://www.healio.com/ophthalmology/journals/jpos/2012-7-49-4/%7B87e0bd37-0db2-4559-a220-b19734ea8fe7%7D/a-case-of-internal-ophthalmoplegia-associated-with-varicella-zoster
Browse In Surgery, Female, Haematology, Thyroid function, Blood film, Ophthalmoplegia, Creatinine (serum) | EDM Case ReportsBrowse In Surgery, Female, Haematology, Thyroid function, Blood film, Ophthalmoplegia, Creatinine (serum) | EDM Case Reports
Hypopituitarism is a rare presentation of Burkitts lymphoma (BL). The purpose of this report is to present a case of BL presenting with panhypopituitarism and to review other case reports of lymphoma presenting with pituitary dysfunction to highlight the distinguishing features of these cases from other benign aetiologies of pituitary dysfunction such as non-functioning pituitary adenomas. We reviewed a total of 11 cases of lymphoma presenting with pituitary dysfunction published from 1998 to 2013 including the present case. The demographics, clinical presentations, laboratory features, radiological findings, histological diagnosis, treatment administered and outcomes were described. Of the total number of patients, 45.5% of the cases had diffuse large B-cell lymphoma while 27.3% had BL. Anterior pituitary dysfunction was more common than posterior pituitary dysfunction at presentation. The other common associated presenting symptoms were painful ophthalmoplegia, cranial nerve palsies and ...
https://edm.bioscientifica.com/browse?pageSize=10&sort=datedescending&t=related-disciplines_20&t_0=gender_0&t_1=related-disciplines_24&t_2=investigation_373&t_3=investigation_53&t_4=signs-symptoms_529&t_5=investigation_112
Browse In Ophthalmoplegia, Haematology, Thyroid function, Anaemia, Female, Signs and Symptoms, Blood film, Gland/Organ | EDM...Browse In Ophthalmoplegia, Haematology, Thyroid function, Anaemia, Female, Signs and Symptoms, Blood film, Gland/Organ | EDM...
Hypopituitarism is a rare presentation of Burkitts lymphoma (BL). The purpose of this report is to present a case of BL presenting with panhypopituitarism and to review other case reports of lymphoma presenting with pituitary dysfunction to highlight the distinguishing features of these cases from other benign aetiologies of pituitary dysfunction such as non-functioning pituitary adenomas. We reviewed a total of 11 cases of lymphoma presenting with pituitary dysfunction published from 1998 to 2013 including the present case. The demographics, clinical presentations, laboratory features, radiological findings, histological diagnosis, treatment administered and outcomes were described. Of the total number of patients, 45.5% of the cases had diffuse large B-cell lymphoma while 27.3% had BL. Anterior pituitary dysfunction was more common than posterior pituitary dysfunction at presentation. The other common associated presenting symptoms were painful ophthalmoplegia, cranial nerve palsies and ...
https://edm.bioscientifica.com/browse?pageSize=10&sort=datedescending&t_0=signs-symptoms_529&t_1=related-disciplines_24&t_2=investigation_373&t_3=signs-symptoms_37&t_4=gender_0&t_5=signs-symptoms&t_6=investigation_53&t_7=gland
Pattern of ocular involvement in myasthenia gravis with MuSK antibodies | Journal of Neurology, Neurosurgery & PsychiatryPattern of ocular involvement in myasthenia gravis with MuSK antibodies | Journal of Neurology, Neurosurgery & Psychiatry
Results Ocular manifestations were observed in 79 patients (96.4%) and were the presenting symptoms in 48 (58.5%). Intermittent diplopia with subtle ophthalmoparesis was the most common complaint, ptosis was generally symmetrical and conjugated gaze paresis occurred in 35% of the patients. Ocular manifestations responded well to prednisone and partially to symptomatic treatment. A few patients developed chronic symmetrical ophthalmoparesis, associated with persistent weakness in other muscle groups. All patients with ocular presentation progressed to generalised disease, though weakness spread to other muscle groups was considerably delayed in a few cases. ...
http://jnnp.bmj.com/content/88/9/761
Sensory ataxic neuropathy- dysarthria- and ophthalmoparesis - CheckOrphanSensory ataxic neuropathy- dysarthria- and ophthalmoparesis - CheckOrphan
CheckOrphan is a non-profit organization located in Basel, Switzerland and Santa Cruz, California that is dedicated to rare, orphan and neglected diseases. CheckOrphan offers users an interactive and dynamic platform for all these diseases. This strategy allows visitors to be updated daily on all the latest news and interact with people internationally. This is essential, because due to the nature of these diseases, there is not a large concentration of individuals within any given proximity ...
https://checkorphan.org/disease/sensory-ataxic-neuropathy-dysarthria-and-ophthalmoparesis/
Myopathy and Ophthalmoplegia, related diseases and genetic alterations | MENDELIAN.COMyopathy and Ophthalmoplegia, related diseases and genetic alterations | MENDELIAN.CO
MYOPATHY and OPHTHALMOPLEGIA related symptoms, diseases, and genetic alterations. Get the complete information with our medical search engine for phen
https://www.mendelian.co/symptoms/myopathy-and-ophthalmoplegia
Getting the best out of the global ophthalmoplegia market - WhaTechGetting the best out of the global ophthalmoplegia market - WhaTech
The Ophthalmoplegia Market report summarizes the industry on the basis of treatment. The market is segmented into surgery, drug treatment, and others. The surgery sector is further segmented into strabismus surgery and others.
https://www.whatech.com/market-research/medical/385578-getting-the-best-out-of-the-global-ophthalmoplegia-market
Fovilles syndrome - wikidocFovilles syndrome - wikidoc
Fovilles syndrome is caused by the blockage of the perforating branches of the basilar artery in the region of the brainstem known as the pons.[1] Structures affected by the infarct are the PPRF, nuclei of cranial nerves VI and VII, corticospinal tract, medial lemniscus, and the MLF. This produces ipsilateral horizontal gaze palsy and Bells Palsy and contralateral hemiparesis, hemisensory loss, and internuclear ophthalmoplegia. ...
http://wikidoc.org/index.php/Foville%27s_syndrome
Supranuclear and Internuclear Oculomotor Disturbances - Multiple SclerosisSupranuclear and Internuclear Oculomotor Disturbances - Multiple Sclerosis
Internuclear ophthalmoplegia INO is characterized by inability to adduct one eye, combined with nystagmus of the other, abducted eye dissociated nystagmus , on
https://www.mussenhealth.us/multiple-sclerosis/supranuclear-and-internuclear-oculomotor-disturbances.html
Vi - Multiple Sclerosis - Derick Mussen HealthcareVi - Multiple Sclerosis - Derick Mussen Healthcare
- Nucleus praepositus hypoglossi lateral gaze Neuroanatomy of internuclear ophthalmoplegia INO shown left INO on rightward gaze leftward, rightward, and
https://www.mussenhealth.us/multiple-sclerosis/iv-vi.html
aloewood libration densify vetusty
restitution idiomorphically unscholar scombriform phosphation moonsickness gombeenism unsuspectible exploitative predevote kawika scrike merlette photesthesis pastry revelation latheron atomizer toyingly ophthalmoplegia [email protected] ...
http://origami.happymagpie.com/cgi-bin/email.cgi/ule
Best Rescues of 2013 from Pet Adoption Network | Pets Fur KeepsBest Rescues of 2013 from Pet Adoption Network | Pets Fur Keeps
As we prepare for another busy and rewarding year of rescue, it is inspiring to look back at the rescues of 2013. Here are some of the most memorable stories:Clive and Callum These one-and-a-half year old brothers came to us from a horrific situation: a mentally ill person had kept them confined in small…
https://petsfurkeeps.wordpress.com/2014/01/03/best-rescues-of-2013-from-pet-adoption-network/
Neo-B12 Injection - NPS MedicineWiseNeo-B12 Injection - NPS MedicineWise
Neo-B12® Injection is usually stored in the doctors surgery or clinic, or at the pharmacy. The injection is kept in a cool dry place where the temperature stays below 25°C.. If you need to store Neo-B12® Injection, keep it in the original pack until it is time for it to be given. If you take the ampoules out of the pack, they will not keep well.. Keep Neo-B12® Injection in a cool dry place, where the temperature stays below 25°C.. Do not store this medicine or any other medicine in the bathroom or near a sink. Do not leave it in the car on hot days, or on window sills. Heat and dampness can destroy some medicines.. Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.. ...
https://www.nps.org.au/medicine-finder/neo-b12-solution-for-injection
A robot to watch out for defects | ILC NewslineA robot to watch out for defects | ILC Newsline
A small group of young researchers at DESY, Germany, is working on a robot that could drastically reduce the time it takes to optically inspect a cavity. Their work covers everything from the pure mechanics of the workbench and fine-tuned motors for moving the heavy parts to developing sophisticated methods of automatically analysing the pictures. Cavities might eventually pass the check in two hours instead of the one-and-a-half days it takes today.
https://newsline.linearcollider.org/2011/04/14/a-robot-to-watch-out-for-defects/
Cancer, Chemo or Old Age? - TIME GOES BYCancer, Chemo or Old Age? - TIME GOES BY
Thats the question I spend some of my time trying to figure out. A new pain in my elbow. Nausea if I eat one more bite. A nose so runny I use up one-and-a-half boxes of Kleenex in a day....
https://www.timegoesby.net/weblog/2019/05/cancer-chemo-or-old-age.html?cid=6a00d8341c85cd53ef0240a482a175200d
Cancer, Chemo or Old Age? - TIME GOES BYCancer, Chemo or Old Age? - TIME GOES BY
Thats the question I spend some of my time trying to figure out. A new pain in my elbow. Nausea if I eat one more bite. A nose so runny I use up one-and-a-half boxes of Kleenex in a day....
https://www.timegoesby.net/weblog/2019/05/cancer-chemo-or-old-age.html?cid=6a00d8341c85cd53ef0240a48284ed200d
Why I REFUSE To Let Infertility Win | YourTangoWhy I REFUSE To Let Infertility Win | YourTango
After one-and-a-half years of fruitless (and awkward) babymaking sex and the threat of separation, we decided it was time to move forward with Plan B and seek out fertility testing.
https://www.yourtango.com/2012151153/beating-infertility-we-will-become-parents-no-matter-what/page/3
Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2 - Get your...Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2 - Get your...
Exosomal MiR-744 Inhibits Proliferation and Sorafenib Chemoresistance in Hepatocellular Carcinoma by Targeting PAX2 - Get your full text copy in PDF #919219
https://www.medscimonit.com/download/index/idArt/919219
Clinical features, ARIX and PHOX2B nucleotide changes in three families with congenital superior oblique muscle palsy<...
TY - JOUR. T1 - Clinical features, ARIX and PHOX2B nucleotide changes in three families with congenital superior oblique muscle palsy. AU - Imai, Sayuri. AU - Matsuo, Toshihiko. AU - Itoshima, Emi. AU - Ohtsuki, Hiroshi. PY - 2008/2. Y1 - 2008/2. N2 - We analyzed nucleotide changes in 3 genes, ARIX, PHOX2B, and KIF21A, in 6 patients of 3 families with congenital superior oblique muscle palsy. Three exons of ARIX, 3 exons of PHOX2B, and exons 8, 20, and 21 of KIF21A were amplified by polymerase chain reaction from genomic DNA isolated from the peripheral blood. The DNA fragments were directly sequenced in both directions. In 2 different families, a heterozygous nucleotide change, ARIX 153G , A, in the 5′-untranslated region was found in common between a father and daughter with muscle palsy and between a mother and daughter with muscle palsy (Family No. 1 and No. 3). In the other family (Family No. 2), a heterozygous 15-nucleotide deletion, PHOX2B 1124del15, resulting in loss of 5 alanine ...
https://okayama.pure.elsevier.com/en/publications/clinical-features-arix-and-phox2b-nucleotide-changes-in-three-fam
Progressive external ophthalmoplegia - Genetics Home ReferenceProgressive external ophthalmoplegia - Genetics Home Reference
Progressive external ophthalmoplegia is a condition characterized by weakness of the eye muscles. The condition typically appears in adults between ages 18 and 40 and slowly worsens over time. The first sign of progressive external ophthalmoplegia is typically drooping eyelids (ptosis), which can affect one or both eyelids. As ptosis worsens, affected individuals may use the forehead muscles to try to lift the eyelids, or they may lift up their chin in order to see. Another characteristic feature of progressive external ophthalmoplegia is weakness or paralysis of the muscles that move the eye (ophthalmoplegia). Affected individuals have to turn their head to see in different directions, especially as the ophthalmoplegia worsens. People with progressive external ophthalmoplegia may also have general weakness of the muscles used for movement (myopathy), particularly those in the neck, arms, or legs. The weakness may be especially noticeable during exercise (exercise intolerance). Muscle weakness ...
https://ghr.nlm.nih.gov/condition/progressive-external-ophthalmoplegia
Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 6 disease: Malacards - Research...Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 6 disease: Malacards - Research...
MalaCards based summary : Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 6, also known as progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant, 6, is related to rapadilino syndrome and baller-gerold syndrome, and has symptoms including myalgia, muscle cramp and facial paresis. An important gene associated with Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 6 is DNA2 (DNA Replication Helicase/Nuclease 2), and among its related pathways/superpathways is Cytosolic iron-sulfur cluster assembly. Related phenotypes are progressive external ophthalmoplegia and limb-girdle muscle weakness ...
https://www.malacards.org/card/progressive_external_ophthalmoplegia_with_mitochondrial_dna_deletions_autosomal_dominant_6_2
Chronic Progressive External OphthalmoplegiaChronic Progressive External Ophthalmoplegia
Chronic progressive external ophthalmoplegia (CPEO) is a mitochondrial disorder stemming from several genetic mutations. The most characteristic feature of the disease is extraocular muscle weakness leading to ptosis and limited eye movements. Generalized weakness, cataracts, ataxia, depression, heart conduction abnormalities, and hearing loss are other notable manifestations of the disease. The diagnosis rests on a thorough clinical assessment followed by imaging and muscle biopsy studies. Molecular genetic testing for detection of mitochondrial DNA mutations is necessary for a confirmation of the diagnosis.… Chronic Progressive External Ophthalmoplegia (CPEO): Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis.
https://www.symptoma.com/en/info/chronic-progressive-external-ophthalmoplegia
Left vertebral artery dissection causing bilateral internuclear ophthalmoplegia<...
TY - JOUR. T1 - Left vertebral artery dissection causing bilateral internuclear ophthalmoplegia. AU - Jickling, Glen. AU - Leung, Kelvin. AU - Gan, Kenman. AU - Shuaib, Ashfaq. AU - Lewis, James. AU - Mouradian, Mikael S.. PY - 2008/9. Y1 - 2008/9. N2 - A 21-year-old woman presented to the emergency department 1 day after a fall. On the day of presentation, she awoke with horizontal diplopia and posterior neck pain. Based on clinical findings, she was diagnosed with bilateral internuclear ophthalmoplegia. A conventional angiogram identified a left vertebral artery dissection. She was started on anticoagulant therapy, with gradual improvement of her diplopia over several months. Diplopia is frequently seen in the emergency department. Internuclear ophthalmoplegia is a cause of binocular diplopia and is important to recognize because it indicates a brainstem lesion requiring neurologic evaluation.. AB - A 21-year-old woman presented to the emergency department 1 day after a fall. On the day of ...
https://ucdavis.pure.elsevier.com/en/publications/left-vertebral-artery-dissection-causing-bilateral-internuclear-o
Anticipation of autosomal dominant progressive external ophthalmoplegia with hypogonadismAnticipation of autosomal dominant progressive external ophthalmoplegia with hypogonadism
A large Swedish family with members affected by progressive external ophthalmoplegia with hypogonadism were followed-up and reviewed. Hypogonadism included delayed sexual maturation, primary amenorrhea, early menopause, and testicular atrophy. Cataracts, cerebellar ataxia, neuropathy, hypoacusia, pes cavus, tremor, parkinsonism, depression, and mental retardation were other features observed in this family. Muscle biopsy samples of advanced cases showed ragged-red fibers, focal cytochrome c oxidase deficiency, and multiple mtDNA deletions by Southern blot analysis. An autosomal dominant mode of inheritance was evident with anticipation in successive generations. Linkage analysis excluded the chromosome 10q23.3-q24.3 region reported as being linked to the disease in a Finnish family with autosomal dominant progressive external ophthalmoplegia. We report for the first time clinical evidence for anticipation in a family with autosomal dominant progressive external ophthalmoplegia. We hypothesize ...
http://uu.diva-portal.org/smash/record.jsf?pid=diva2:84322
Chronic Progressive External Ophthalmoplegia(CPEO): A not so rare mitochondrial myopathy-PJMS-IP Innovative Publication Pvt. Ltd
Chronic Progressive External Ophthalmoplegia(CPEO): A not so rare mitochondrial myopathy-PJMS-Print ISSN No:-2249-8176 Online ISSN No:-2348-7682Article DOI No:-10.18231,Panacea Journal of Medical Sciences-IP Innovative Publication Pvt Limited, Medical Journals Publication, Open Access Journals, Print Journals,Indian
https://www.innovativepublication.com/journal-article-details/PJMS/article/3304/volume/102/issue/288
Chronic progressive external ophthalmoplegia definition | Drugs.comChronic progressive external ophthalmoplegia definition | Drugs.com
Definition of chronic progressive external ophthalmoplegia. Provided by Stedmans medical dictionary and Drugs.com. Includes medical terms and definitions.
https://www.drugs.com/dict/chronic-progressive-external-ophthalmoplegia.html
Chronic Progressive External Ophthalmoplegia: Disease Bioinformatics: Novus BiologicalsChronic Progressive External Ophthalmoplegia: Disease Bioinformatics: Novus Biologicals
Learn more about Chronic Progressive External Ophthalmoplegia from related diseases, pathways, genes and PTMs with the Novus Bioinformatics Tool.
https://www.novusbio.com/diseases/chronic-progressive-external-ophthalmoplegia
Tolosa-Hunt Syndrome Differential DiagnosesTolosa-Hunt Syndrome Differential Diagnoses
Tolosa-Hunt syndrome (THS) is a painful ophthalmoplegia caused by nonspecific inflammation of the cavernous sinus or superior orbital fissure. See the image below.
https://emedicine.medscape.com/article/1146714-differential
Tolosa-Hunt Syndrome: Background, Pathophysiology, EpidemiologyTolosa-Hunt Syndrome: Background, Pathophysiology, Epidemiology
Tolosa-Hunt syndrome (THS) is a painful ophthalmoplegia caused by nonspecific inflammation of the cavernous sinus or superior orbital fissure. See the image below.
https://emedicine.medscape.com/article/1146714-overview
Tolosa-Hunt Syndrome: Background, Pathophysiology, EpidemiologyTolosa-Hunt Syndrome: Background, Pathophysiology, Epidemiology
Tolosa-Hunt syndrome (THS) is a painful ophthalmoplegia caused by nonspecific inflammation of the cavernous sinus or superior orbital fissure. See the image below.
https://emedicine.staging.medscape.com/article/1146714-overview
Mechanisms of vertical fusional vergence in patients with congenital superior oblique paresis investigated with an eye...
TY - JOUR. T1 - Mechanisms of vertical fusional vergence in patients with congenital superior oblique paresis investigated with an eye-tracking haploscope. AU - Irsch, Kristina. AU - Guyton, David Lee. AU - Park, Hee Jung S. AU - Ying, Howard S.. PY - 2015. Y1 - 2015. N2 - PURPOSE. To determine the mechanisms of vertical fusional vergence in patients with congenital unilateral superior oblique paresis (SOP) and to discuss the implications of these mechanisms. METHODS. Eleven patients were examined with our eye-tracking haploscope. RESULTS. Three different fusion mechanisms were found, producing significantly different cyclovergence to vertical vergence ratios (P ,0.05): primary use of the vertical rectus muscles in seven patients (ratio: 0.36 6 1.6), primary use of the oblique muscles in one patient (0.04), and use of the superior oblique muscle in the higher eye and the superior rectus muscle in the lower eye in three patients (1.15 6 0.32). Lancaster red-green testing showed alignment ...
https://jhu.pure.elsevier.com/en/publications/mechanisms-of-vertical-fusional-vergence-in-patients-with-congeni-5
What does kearns-sayre syndrome mean?What does kearns-sayre syndrome mean?
Definition of kearns-sayre syndrome in the Definitions.net dictionary. Meaning of kearns-sayre syndrome. What does kearns-sayre syndrome mean? Information and translations of kearns-sayre syndrome in the most comprehensive dictionary definitions resource on the web.
http://www.definitions.net/definition/kearns-sayre%20syndrome
External Ophthalmoplegia Associated With Hashimotos Thyroiditis and Recovered on Corticosteroid TreatmentExternal Ophthalmoplegia Associated With Hashimotos Thyroiditis and Recovered on Corticosteroid Treatment
Five-year follow-up of a young male patient is presented. Total external ophthalmoplegia developed 1 week after an upper respiratory tract infection. After 3 years of the course, hyperthyreosis and clinical signs of thyroid-associated ophthalmopathy occurred. Hashimotos thyroiditis and ultrastructural signs of mitochondrial damage of striated muscle were found by histological investigations. The paresis of the external ocular muscles recovered after long-term corticosteroid treatment. On the basis of clinical symptoms and histological results, the authors supposed that an immunological reaction had caused mitochondrial damage in the striated muscles, which also resulted in thyroiditis. This case history points that autoimmune mechanism more frequently might participate in the pathogenesis of chronic external ophthalmoplegia, and the symptoms might precede organ-specific or perhaps systemic autoimmune disorders.. ...
http://liu.diva-portal.org/smash/record.jsf?pid=diva2:553097
Medical Genetics Test Details - Baylor Genetics Laboratories - Baylor College of Medicine, Houston, TexasMedical Genetics Test Details - Baylor Genetics Laboratories - Baylor College of Medicine, Houston, Texas
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes and Healthcare Common Procedure Coding System (HCPCS) codes listed, are provided for informational purposes only. The codes reflect our interpretation of CPT/HCPCS coding requirements based upon AMA guidelines published annually. CPT/HCPCS codes are provided only as guidance to assist clients with billing. Baylor Genetics strongly recommends that clients confirm CPT/HCPCS codes with their Medicare Administrative Contractor (MAC) or other payer being billed, as requirements may differ. CPT coding is the sole responsibility of the billing party. Baylor Genetics assumes no responsibility for billing errors due to reliance on the CPT codes listed. Please direct any questions regarding CPT coding to the payer being billed. ...
https://www.bcm.edu/research/medical-genetics-labs/test_detail.cfm?testcode=3069&show=1
Klitorishypertrophie Nivala - Affiliate dating...
but they are mainly a cosmetic nuisance and never become going. Operating on a keloid usually forests more scar tissue to form, so klitotishypertrophie with fairways may have been told that there is nothing that can be done to get rid of them. Facilities may be often be prevented by using a pressure dressing, software gel pad or paper tape over the injury tourist.. These are left on for 23 of 24 athletics each day. Dacryoadenitis Epiphora Dacryocystitis Xerophthalmia. Exophthalmos Enophthalmos Different cellulitis Orbital lymphoma Periorbital klitorishypertrophie nivala. Conjunctivitis allergic Pterygium Pinguecula Subconjunctival back. Cataract Congenital cataract Childhood cataract Aphakia Klitorishypertrophue lentis.. Ophthalmoparesis Chronic progressive external ophthalmoplegia Kearns-Sayre opportunity. Conjugate gaze palsy Convergence insufficiency Internuclear ophthalmoplegia One and a acceptable syndrome. Hemianopsia binasal bitemporal homonymous Quadrantanopia. Teaching Hemeralopia ...
http://danaliz.ru/klitorishypertrophie-nivala.php
Tolosa-Hunt syndrome - WikipediaTolosa-Hunt syndrome - Wikipedia
Tolosa-Hunt syndrome (THS) is a rare disorder characterized by severe and unilateral headaches with orbital pain, along with weakness and paralysis (ophthalmoplegia) of certain eye muscles (extraocular palsies). In 2004, the International Headache Society provided a definition of the diagnostic criteria which included granuloma. Symptoms are usually limited to one side of the head, and in most cases the individual affected will experience intense, sharp pain and paralysis of muscles around the eye. Symptoms may subside without medical intervention, yet recur without a noticeable pattern. In addition, affected individuals may experience paralysis of various facial nerves and drooping of the upper eyelid (ptosis). Other signs include double vision, fever, chronic fatigue, vertigo or arthralgia. Occasionally the patient may present with a feeling of protrusion of one or both eyeballs (exophthalmos). The exact cause of THS is not known, but the disorder is thought to be, and often assumed to be, ...
https://en.wikipedia.org/wiki/Tolosa%E2%80%93Hunt_syndrome
Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 5 disease: Malacards - Research...Progressive External Ophthalmoplegia with Mitochondrial Dna Deletions, Autosomal Dominant 5 disease: Malacards - Research...
UniProtKB/Swiss-Prot : 72 Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant, 5: A disorder characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism ...
https://www.malacards.org/card/progressive_external_ophthalmoplegia_with_mitochondrial_dna_deletions_autosomal_dominant_5
Isolated third nerve palsy: A rare neurological presentation of Burkitts lymphoma<...
TY - JOUR. T1 - Isolated third nerve palsy. T2 - A rare neurological presentation of Burkitts lymphoma. AU - Kalantri, Siddhesh Arun. AU - Nayak, Akshatha. AU - Datta, Saikat. AU - Bhattacharyya, Maitreyee. PY - 2017/1/1. Y1 - 2017/1/1. N2 - Lymphoma patient presenting with isolated third nerve palsy is relatively rare, and diagnosis of underlying disease may be challenging. Until this date, less than 20 cases have been described in the literature. This is the case of a 3-year-old boy who presented to neurologist with ptosis of left eye for 8 days. On examination, abdominal mass was detected, and the child was referred to paediatric surgery department. Laparotomy and excision of the mass was done. Histopathology and immunohistochemistry of the mass confirmed it to be a case of Burkitts lymphoma. At this point, the patient was referred to haematology department. Contrast-enhanced CT brain showed infiltration around left cavernous sinus. Patient was treated with two cycles of R-CODOX-M/R-IVAC. ...
https://manipal.pure.elsevier.com/en/publications/isolated-third-nerve-palsy-a-rare-neurological-presentation-of-bu
High-Field MRI Contribution in Tolosa-Hunt Syndrome (THS). Report of Two Cases and Review of Literature - Open Journal of...High-Field MRI Contribution in Tolosa-Hunt Syndrome (THS). Report of Two Cases and Review of Literature - Open Journal of...
Background: Tolosa Hunt Syndrome is an inflammatory condition of unknown etiology of the cavernous sinus and superior orbital fissure. Because of the difficulty in establishing histological evidence, his diagnosis is based on a set of arguments established by the International Headache Society. MRI allows indirect visualization of the granuloma and plays a key role in diagnosis and follow-up. Aim: To illustrate High-field MRI contribution in Tolosa-Hunt Syndrome (THS). Cases Presentation: Two patients, a 25-year-old female and a 40-year-old male were recruited in this retrospective case report study at the Radiology service of Fann University Hospital (Dakar Senegal). The first patient has been suffering from a right retro-orbital pain and diplopia for 2 months and the second from a painful oculomotor nerve palsy for 3 months. Blood tests, lumbar puncture, thyroid hormone levels and an infectious screen were done. Screening for converting enzymes, and serum antibodies were also done. They underwent a
https://www.scirp.org/journal/paperinforcitation.aspx?paperid=86112
Re: Alternative approaches to Chronic progressive external ophthalmoplegia (CPEO) (Eyesight Forum) 8/14/2011 1846194Re: Alternative approaches to Chronic progressive external ophthalmoplegia (CPEO) (Eyesight Forum) 8/14/2011 1846194
Hi, Did you tried colloidal silver? You can prepare a solution with colloidal silver diluted with purified water in a proportion like 1:50. Use one drop in one eye one time per day to check the result. If things go well rise the number of drops per day and use in both eyes. Hope this help.
https://www.curezone.org/forums/fm.asp?i=1846194
HealthBoards - View Single Post - Chronic Progressive External Ophthalmoplegia (CPEO)HealthBoards - View Single Post - Chronic Progressive External Ophthalmoplegia (CPEO)
Post 4763455 - Health related message boards offering discussions of numerous health topics including allergies, cancer, diabetes, heart disease, exercise, attention deficit disorder, diet, and nutrition.
https://www.healthboards.com/boards/4763455-post10.html
Oculomotor palsy due to diabetes - RightDiagnosis.comOculomotor palsy due to diabetes - RightDiagnosis.com
List of disease causes of Oculomotor palsy due to diabetes, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or symptoms for Oculomotor palsy due to diabetes.
http://www.rightdiagnosis.com/sym/oculomotor_palsy_due_to_diabetes.htm
Minicore myopathy with external ophthalmoplegia | Genetic and Rare Diseases Information Center (GARD) - an NCATS...Minicore myopathy with external ophthalmoplegia | Genetic and Rare Diseases Information Center (GARD) - an NCATS...
A collection of disease information resources and questions answered by our Genetic and Rare Diseases Information Specialists for Minicore myopathy with external ophthalmoplegia
https://rarediseases.info.nih.gov/diseases/10316/index
External ophthalmoplegia Definition & Meaning | Dictionary.comExternal ophthalmoplegia Definition & Meaning | Dictionary.com
External ophthalmoplegia definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now!
https://www.dictionary.com/browse/external-ophthalmoplegia
Ophthalmoplegic | Article about ophthalmoplegic by The Free DictionaryOphthalmoplegic | Article about ophthalmoplegic by The Free Dictionary
Looking for ophthalmoplegic? Find out information about ophthalmoplegic. a paralysis of one or more cranial nerves by which the eye muscles are innervated. Ophthalmoplegia may be congenital-a result of underdevelopment of the... Explanation of ophthalmoplegic
https://encyclopedia2.thefreedictionary.com/ophthalmoplegic
One-and-a-half syndrome secondary to transorbital penetrating injury | NeurologyOne-and-a-half syndrome secondary to transorbital penetrating injury | Neurology
A 46-year-old woman sustained a penetrating left eye (OS) injury after tripping and falling onto a motorcycle antenna. She removed the antenna immediately and presented to the emergency room complaining of diplopia. Examination demonstrated proptosis and subconjunctival hemorrhage OS. Her diplopia was initially attributed to mechanical restriction OS secondary to retrobulbar hemorrhage visualized on CT scan (figure 1). Careful examination, however, revealed left conjugate horizontal gaze palsy and left internuclear ophthalmoplegia. This was consistent with one-and-a-half syndrome from left pons penetrating trauma, confirmed on MRI (figure 2). Two months later, her condition had improved, but she continued to demonstrate abduction paresis OS. ...
http://n.neurology.org/content/90/2/91.full
Fisher one-and-a-half syndrome due to a bulb protuberance cavernoma | Archivos de la Sociedad Española de Oftalmología (English...Fisher one-and-a-half syndrome due to a bulb protuberance cavernoma | Archivos de la Sociedad Española de Oftalmología (English...
The one and a half Fisher syndrome is produced by a unilateral lesion in the dorsal and inferior part of the pons located specifically in the pontine tegmentum. This is an area that contains the medial longitudinal fasciculus (LMF), the paramedian pontine reticular formation (PPRF) and the nucleus of the sixth cranial nerve, responsible for the horizontal movements of the gaze. Clinically it manifests with conjugate gaze palsy with internuclear ophthalmoplegia.. The case is reported on a 60 year-old patient, who presented with binocular diplopia, ophthalmoplegia and paralysis of the gaze conjugated to the left. Imaging studies were performed that showed a hemi-protuberant hematoma secondary to a cavernoma. As expected, he presented with several episodes of re-bleeding with clinical worsening: headache, diplopia, tetraparesis, and hypoaesthesia in the right side of the face, as such that the microsurgical exeresis of the protuberant cavernoma was considered.. ...
https://www.elsevier.es/en-revista-archivos-sociedad-espanola-oftalmologia-english-496-articulo-fisher-one-and-a-half-syndrome-due-bulb-S2173579419300234
Difference between revisions of Congenital Third Nerve Palsy - EyeWikiDifference between revisions of Congenital Third Nerve Palsy - EyeWiki
Cranial nerve three (CN3) palsies are overall rare in the pediatric population with up to 50% diagnosed as congenital, followed by trauma, inflammation, and vascular etiologies .[1] [2] [3] It may also uncommonly present in the setting of migraine, infection, or neoplasm. [1][4] When combined with both congenital sixth and forth nerve palsies, congenital third nerve palsies have an estimated incidence of 7.6 per 100,000. [5]
https://eyewiki.org/w/index.php?title=Congenital_Third_Nerve_Palsy&curid=8299&diff=68219&oldid=65054
T-Cell Lymphoma Presenting as Painful OphthalmoplegiaT-Cell Lymphoma Presenting as Painful Ophthalmoplegia
Localized T-cell lymphoma in the orbit should be treated carefully with planned local radiation plus systemic chemotherapy. However, prognosis is poor once dissemination occurs, and long-term remissions, even with aggressive chemotherapy, are rare.11 Saga et al2 reported two patients with peripheral T-cell lymphoma involving the orbit secondarily from the testicular lymphoma. The patients received chemotherapy and local radiation, but died of progression of the disease. Leidenix et al7 reported the case of primary T-cell lymphoma confined to the orbit in a pediatric patient. The patient received surgical excision, systemic chemotherapy, and local radiation and died of dissemination of the disease. Hassan and Elner6 reported orbital peripheral T-cell lymphoma in a child who responded to local radiation and systemic chemotherapy. T-cell lymphoma is generally rapidly progressive and likely to have a high mortality despite aggressive treatment ...
https://www.ekjo.org/journal/view.php?number=447
Ophthalmoplegia in both eyes and Permanent brain damage - Symptom Checker - check medical symptoms at RightDiagnosisOphthalmoplegia in both eyes and Permanent brain damage - Symptom Checker - check medical symptoms at RightDiagnosis
List of 44 causes for Ophthalmoplegia in both eyes and Permanent brain damage, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
http://wrongdiagnosis.com/cosymptoms/ophthalmoplegia-in-both-eyes/permanent-brain-damage.htm
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 3Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 3
Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
https://pharos.nih.gov/idg/diseases/umls:C1836439
progressive external ophthalmoplegiaprogressive external ophthalmoplegia
a slowly progressing, bilateral myopathy often affecting only the extraocular muscles, but sometimes also the orbicularis oculi. The levators of the upper lids are usually affected first, with ptosis resulting, followed by progressive, total…
https://medicine.enacademic.com/146915/progressive
Tolosa-Hunt syndrome in uraemic patients undergoing maintenance haemodialysis. : Nephrology Dialysis Transplantation - oi
We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time.Find out more ...
http://oxfordindex.oup.com/view/10.1093/ndt/13.9.2370
What is strabismus and how common is it? - AAPOSWhat is strabismus and how common is it? - AAPOS
There are many different types of strabismus. Strabismus is most commonly described by the direction of the eye misalignment; common types of strabismus are esotropia, exotropia, hypotropia, and hypertropia.. Strabismus can also be described by its cause. The 3 cranial nerves (III, IV, VI) responsible for eye movement can be weak or palsied and cause strabismus. Some examples of paralytic strabismus include third nerve palsy and superior oblique palsy.. Special patterns of strabismus can have unique names such as Brown syndrome, and Duane syndrome.. ...
https://aapos.org/terms/faqs/14
A diagnostic conundrum | Practical NeurologyA diagnostic conundrum | Practical Neurology
A 26-year-old man was referred with facial weakness, dysarthria, dysphagia, ophthalmoparesis and severely weak and wasted legs. His symptoms had begun when aged 20 with electric shock pains and paraesthesia in both feet progressing over 6 months to the lower calves. He then developed buttock numbness and occasional faecal incontinence. By age 22, he had diffuse lower limb weakness and wasting, with difficulty standing from a seated position and frequent tripping. He became wheelchair-dependent within 3 years.. Over the same time period, he developed progressive facial weakness, bilateral ptosis, slurred speech, difficulty chewing and swallowing and lost 10 kg of weight. He reported hearing difficulty, and an audiogram showed high-frequency hearing loss. Important negatives included absence of upper limb symptoms, autonomic, cardiac, respiratory or cognitive dysfunction ...
http://pn.bmj.com/content/early/2018/01/23/practneurol-2017-001801
Herpes OphthalmicusHerpes Ophthalmicus
This page includes the following topics and synonyms: Herpes Ophthalmicus, Zoster Ophthalmicus, Herpes Zoster Ophthalmicus, Ophthalmic Herpes Zoster, Hutchinsons Sign.
https://fpnotebook.com/mobile/Neuro/CN/HrpsOphthlmcs.htm
BEYOND Headaches: Migraine Ophthalmoplegic
Take a moment right now to view the free Beyond Headaches Lifestyle tour for the 3 most useful tips when dealing with ophthalmoplegic migraines.
http://www.beyondheadaches.com/Migraine_Ophthalmoplegic.html
DJO | Digital Journal of OphthalmologyDJO | Digital Journal of Ophthalmology
The finding of globe retraction on attempted adduction and grossly normal looking adducting saccades indicated a restrictive etiology rather than a left medial rectus paresis or left internuclear ophthalmoplegia. The orbital CT scan effectively ruled out thyroid orbitopathy or orbital mass. On a subsequent visit, the patient insisted that this was acquired in the past few years and definitely not congenital. He denied any previous operations or trauma to the left eye. It was not until he was getting ready to leave that his wife asked if his ocular motility problems could be related to injections into the eye that he had received 5 years earlier while being treated for iritis OS. His previous ophthalmologist had since left town; however, we were able to obtain his records. These indicated that he had received a series of subconjunctival methylprednisolone injections OS under retrobulbar anaesthesia with xylocaine for iritis ...
http://www.djo.harvard.edu/print.php?url=/physicians/gr/307&print=1
cerebellum | New England Wheelchair Vancerebellum | New England Wheelchair Van
The first signs of Leigh syndrome seen in infancy are usually vomiting, diarrhea, and difficulty swallowing (dysphagia) that leads to eating problems. These problems often result in an inability to grow and gain weight at the expected rate (failure to thrive). Severe muscle and movement problems are common in Leigh syndrome. Affected individuals may develop weak muscle tone (hypotonia), involuntary muscle contractions (dystonia), and problems with movement and balance (ataxia). Loss of sensation and weakness in the limbs (peripheral neuropathy), common in people with Leigh syndrome, may also make movement difficult.. Several other symptoms may occur in people with Leigh syndrome. Many affected individuals develop weakness or paralysis of the muscles that move the eyes (ophthalmoparesis); rapid, involuntary eye movements (nystagmus); or degeneration of the nerves that carry information from the eyes to the brain (optic atrophy). Severe breathing problems are common in people with Leigh syndrome, ...
https://newenglandwheelchairvan.com/tag/cerebellum/
Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis<...
TY - JOUR. T1 - Extensive Involvement of Multiple Cranial and Spinal Nerves in Lymphomatous Meningitis. AU - Cordano, Christian. AU - Nourbakhsh, Bardia. AU - Brown, Ethan. AU - Glastonbury, Christine. PY - 2017/9/1. Y1 - 2017/9/1. KW - B-cell lymphoma. KW - Lymphomatous meningitis. KW - ophthalmoparesis. UR - http://www.scopus.com/inward/record.url?scp=85030784037&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85030784037&partnerID=8YFLogxK. U2 - 10.1017/cjn.2017.50. DO - 10.1017/cjn.2017.50. M3 - Comment/debate. C2 - 28482940. AN - SCOPUS:85030784037. VL - 44. SP - 599. EP - 600. JO - Canadian Journal of Neurological Sciences. JF - Canadian Journal of Neurological Sciences. SN - 0317-1671. IS - 5. ER - ...
https://jhu.pure.elsevier.com/en/publications/extensive-involvement-of-multiple-cranial-and-spinal-nerves-in-ly
A case of Miller Fisher syndrome with anti GQ1b in Thailand. - Oxford Neuroscience
Miller-Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS) and is characterized by the clinical triad of ataxia, ophthalmoplegia, and areflexia. The incidence rate in Thailand has not been established but it occurred approximately 1-5% that of GBS. Here, the authors report a Thai patient diagnosed as MFS that had a positive test of antibodies against the ganglioside GQ1b. These antibodies have diagnostic and pathogenic importance to MFS because of high sensitivity and specificity. All other investigations, such as cerebrospinal fluid analysis, electrophysiological studies, and imaging studies had no significant abnormalities. The patient was successfully treated with intravenous immunoglobulin and fully recovered within one month. After eighteen months follow-up, he is still healthy and has had no recurrent symptoms.
https://www.neuroscience.ox.ac.uk/publications/243048
DMOZ - Health: Conditions and Diseases: Neurological Disorders: Ocular Motility Disorders: Ophthalmoplegia
Paralysis of one or more of the ocular muscles due to disorders of the eye muscles, neuromuscular junction, supporting soft tissue, tendons, or innervation to the muscles.
http://dmoztools.net/Health/Conditions_and_Diseases/Neurological_Disorders/Ocular_Motility_Disorders/Ophthalmoplegia/
Pseudo-Internuclear Ophthalmoplegia | Eccles Health Sciences Library | J. Willard Marriott Digital LibraryPseudo-Internuclear Ophthalmoplegia | Eccles Health Sciences Library | J. Willard Marriott Digital Library
In 1969 this 54 year old man presented with a one month history of blurry vision which started suddenly one afternoon. He said he was just not focusing and he saw two images when he relaxed his sight. He could see clearly covering one eye. Initially, the difficulty in focusing occurred late in the afternoon but as it progressed it appeared earlier and earlier each day. Finally he awoke in the morning with double vision. Past History: Three years prior to admission he had two or three similar transient episodes of blurred vision. On one occasion this occurred at the end of a bowling session when the pins appeared out of focus. Negative for strabismus as a child In 1967 had an episode of chest pain A cardiogram ruled out myocardial infarct Family History: Negative for neurologic disease Symptomatic Inquiry: Negative for generalized fatigue, droopy eyelids, difficulty chewing, swallowing or respiratory difficulty. Neuro-ophthalmic Examination: Visual acuity J1 OU with glasses Visual fields, ...
https://collections.lib.utah.edu/details?id=188590
Conjugate gaze palsy - RightDiagnosis.comConjugate gaze palsy - RightDiagnosis.com
Conjugate gaze palsy symptoms, causes, diagnosis, and treatment information for Conjugate gaze palsy (Supranuclear ocular palsy) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and prognosis.
http://www.rightdiagnosis.com/medical/conjugate_gaze_palsy.htm
Kearns-Sayre syndrome - Rare Disases - Condition | Our HealthKearns-Sayre syndrome - Rare Disases - Condition | Our Health
My aunt has KSS and has been suffering with this for over 30 years. She became a diabetic as a teen and was later diagnosed with KSS. Over the years she has gotten progressively worse. As a result of KSS, she has complete loss of hearing, sight and has also suffers from irregular heart beats which resulted in the need for a pacemaker. Weve noticed that her muscles have become very weak and every month or so she has these episodes I dont know how else to explain them where she becomes almost paralysed....she cant speak, she begins to smack her lips a lot, she becomes complete dead weight. They occur sporadically and if she happens to be walking she fall straight back or if shes sitting shell begin to slide off the chair. This is extremely frightening...many times weve called 911 because we think shes having a stroke. Her doctors havent done much and were pretty much at a loss. Anyone experience anything similar ...
http://www.ourhealth.com/conditions/rare-disases/kearns-sayre-syndrome
2018 ICD-10-CM Codes H49*: Paralytic strabismus2018 ICD-10-CM Codes H49*: Paralytic strabismus
A type 2 excludes note represents not included here. A type 2 excludes note indicates that the condition excluded is not part of the condition it is excluded from but a patient may have both conditions at the same time. When a type 2 excludes note appears under a code it is acceptable to use both the code (H49) and the excluded code together ...
http://www.icd10data.com/ICD10CM/Codes/H00-H59/H49-H52/H49-
Internuclear ophthalmoplegiaInternuclear ophthalmoplegia
... (INO) is a disorder of conjugate lateral gaze in which the affected eye shows impairment of ... "Internuclear Ophthalmoplegia". The Lecturio Medical Concept Library. Retrieved 7 July 2021. (Articles with short description, ... Lana MA, Moreira PR, Neves LB (December 1990). "Wall-eyed bilateral internuclear ophthalmoplegia (Webino syndrome) and ... Multiple sclerosis One and a half syndrome "Internuclear Ophtalmoplegia". Keane JR (May 2005). "Internuclear ophthalmoplegia: ...
https://en.wikipedia.org/wiki/Internuclear_ophthalmoplegia
Chronic progressive external ophthalmoplegiaChronic progressive external ophthalmoplegia
... (CPEO) is a type of eye disorder characterized by slowly progressive inability to ... Those that have diplopia as a result of asymmetric ophthalmoplegia may be corrected with prisms or with surgery to create a ... It is important to differentiate CPEO from other pathologies that may cause an ophthalmoplegia. There are specific therapies ... Treatments used to treat other pathologies causing ophthalmoplegia has not been shown to be effective.[citation needed] ...
https://en.wikipedia.org/wiki/Chronic_progressive_external_ophthalmoplegia
Conjugate eye movementConjugate eye movement
Internuclear ophthalmoplegia: Internuclear ophthalmoplegia affects horizontal gaze, such that one eye is capable of full ... Retrieved from [2] Toral, M., Haugsdal, J., & Wall, M. (2017, June 08). Internuclear Ophthalmoplegia. Retrieved from [3][ ...
https://en.wikipedia.org/wiki/Conjugate_eye_movement
MT-TYMT-TY
Changes in MT-TY may also result in progressive external ophthalmoplegia. Progressive external ophthalmoplegia is characterized ... "Progressive external ophthalmoplegia". Genetics Home Reference. Raffelsberger T, Rossmanith W, Thaller-Antlanger H, Bittner RE ... associated with familial chronic progressive external ophthalmoplegia". Journal of Medical Genetics. 38 (10): 703-5. doi: ...
https://en.wikipedia.org/wiki/MT-TY
MT-TNMT-TN
Mutations in MT-TN have been associated with isolated ophthalmoplegia. Ophthalmoplegia is a condition characterized by eye ... Multiple mutations of 5692A>G and 5703G>A have been found in patients with ophthalmoplegia. Such mutations in MT-TN resulted in ... "Progressive external ophthalmoplegia". Genetics Home Reference. Hao H, Moraes CT (December 1997). "A disease-associated G5703A ...
https://en.wikipedia.org/wiki/MT-TN
Conjugate gaze palsyConjugate gaze palsy
These entities overlap with ophthalmoparesis and ophthalmoplegia. Symptoms of conjugate gaze palsies include the impairment of ... Zee, DS (August 1992). "Internuclear ophthalmoplegia: pathophysiology and diagnosis". Bailliere's Clinical Neurology. 1 (2): ...
https://en.wikipedia.org/wiki/Conjugate_gaze_palsy
OphthalmoparesisOphthalmoparesis
Internal ophthalmoplegia means involvement limited to the pupillary sphincter and ciliary muscle. External ophthalmoplegia ... Ophthalmoplegia is an important finding in orbital cellulitis. The orbit of the eye, including mechanical restrictions of eye ... Complete ophthalmoplegia indicates involvement of both. Ophthalmoparesis can result from disorders of various parts of the eye ... The muscle, as in progressive external ophthalmoplegia or Kearns-Sayre syndrome. The neuromuscular junction, as in myasthenia ...
https://en.wikipedia.org/wiki/Ophthalmoparesis
List of OMIM disorder codesList of OMIM disorder codes
POLG Progressive external ophthalmoplegia, autosomal recessive; 258450; POLG Progressive familial heart block, type IB; 604559 ... C10orf2 Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 4; 610131; POLG2 Progressive ... PGR Progressive external ophthalmoplegia with mitochondrial DNA deletions 3; 609283; SLC25A4 Progressive external ... RRM2B Progressive external ophthalmoplegia, autosomal dominant, with or without hypogonadism; 157640; ...
https://en.wikipedia.org/wiki/List_of_OMIM_disorder_codes
Hubert Maitland TurnbullHubert Maitland Turnbull
with W. Russell Brain: "Exophthalmic ophthalmoplegia". Quarterly Journal of Medicine. 7 (2): 293-324. 1938. Archived from the ...
https://en.wikipedia.org/wiki/Hubert_Maitland_Turnbull
Henry MetzHenry Metz
Metz HS (1976). "Saccadic velocity measurements in internuclear ophthalmoplegia". Am J Ophthalmol. 81 (3): 296-9. PMID 1258953 ...
https://en.wikipedia.org/wiki/Henry_Metz
Hereditary inclusion body myopathyHereditary inclusion body myopathy
Other Names: IBM3; Myopathy with congenital joint contractures, ophthalmoplegia, and rimmed vacuoles; Inclusion body myopathy ... "OMIM# 605637 - Myopathy, Proximal, and Ophthalmoplegia; MYPOP". Online Mendelian Inheritance in Man. Retrieved 19 September ... Myopathy With Congenital Joint Contractures, Ophthalmoplegia, And Rimmed Vacuoles Inclusion Body Myopathy 3, Autosomal Dominant ... Hereditary inclusion body myopathy-joint contractures-ophthalmoplegia syndrome". OrphaNet. Retrieved 19 September 2016. " ...
https://en.wikipedia.org/wiki/Hereditary_inclusion_body_myopathy
Chuan-Pu LeeChuan-Pu Lee
"Progressive Ophthalmoplegia, Glycogen Storage, and Abnormal Mitochondria". Archives of Neurology. 29 (3): 170-179. doi:10.1001/ ... "Progressive Ophthalmoplegia, Glycogen Storage, and Abnormal Mitochondria" (1973, with Salvatore DiMauro, Donald L. Schotland, ...
https://en.wikipedia.org/wiki/Chuan-Pu_Lee
Hutchinsons faciesHutchinson's facies
Hutchinson, J. (1913). "Ophthalmoplegia externa in connection with inherited syphilis". Syphilis. Funk & Wagnalls Co. pp. 483- ... It is named in honour of the English physician Jonathan Hutchinson (1828-1913). When the ophthalmoplegia is complete, the ... Hutchinson's facies is a facial appearance involving drooping eyelids and immobile eyes in external ophthalmoplegia. This sign ... Hutchinson, J. (1879). "On Ophthalmoplegia Externa, or Symmetrical Immobility (partial) of the Eyes, with Ptosis". Medico- ...
https://en.wikipedia.org/wiki/Hutchinson's_facies
Posterior clinoid processesPosterior clinoid processes
Nagaseki Y, Shimizu T, Kakizawa T, Fukamachi A, Nukui H (1989). "Primary internal ophthalmoplegia due to head injury". Acta ... This can cause injury to the pupillomotor fibres of the oculomotor nerve, consequently leading to internal ophthalmoplegia The ...
https://en.wikipedia.org/wiki/Posterior_clinoid_processes
Twinkle (protein)Twinkle (protein)
Hirano M, DiMauro S (December 2001). "ANT1, Twinkle, POLG, and TP: new genes open our eyes to ophthalmoplegia". Neurology. 57 ( ... "Entrez Gene: PEO1 progressive external ophthalmoplegia 1". "TWNK gene". Genetics Home Reference. Diray-Arce, J; Liu, B; Cupp, ... Baloh RH, Salavaggione E, Milbrandt J, Pestronk A (July 2007). "Familial parkinsonism and ophthalmoplegia from a mutation in ... Infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) are associated with multiple ...
https://en.wikipedia.org/wiki/Twinkle_(protein)
Kearns-Sayre syndromeKearns-Sayre syndrome
Suspicion for myopathies should be increased in patients whose ophthalmoplegia does not match a particular set of cranial nerve ... KSS is a more severe syndromic variant of chronic progressive external ophthalmoplegia (abbreviated CPEO), a syndrome that is ... These most often occur years after the development of ptosis and ophthalmoplegia. Atrioventricular (abbreviated "AV") block is ... KEARNS TP; SAYRE GP (1958). "Retinitis Pigmentosa, External Ophthalmoplegia, and Complete Heart Block Unusual Syndrome with ...
https://en.wikipedia.org/wiki/Kearns–Sayre_syndrome
One and a half syndromeOne and a half syndrome
Internuclear ophthalmoplegia Wall M, Wray S (1983). "The one-and-a-half syndrome--a unilateral disorder of the pontine ... More formally, it is characterized by "a conjugate horizontal gaze palsy in one direction and an internuclear ophthalmoplegia ...
https://en.wikipedia.org/wiki/One_and_a_half_syndrome
ArthrogryposisArthrogryposis
... ophthalmoplegia retinopathy, also known as Oculomelic amyoplasia. Arthrogryposis renal dysfunction cholestasis ... ORPHANET - About rare diseases - About orphan drugs Arthrogryposis ophthalmoplegia retinopathy at NIH's Office of Rare Diseases ... ophthalmoplegia, and retinopathy: confirmation of a new type of arthrogryposis". Journal of Medical Genetics. 30 (1): 78-80. ...
https://en.wikipedia.org/wiki/Arthrogryposis
Krembil Research InstituteKrembil Research Institute
Richardson, J. C.; Steele, J; Olszewski, J (1963). "Supranuclear Ophthalmoplegia, Pseudobulbar Palsy, Nuchal Dystonia and ...
https://en.wikipedia.org/wiki/Krembil_Research_Institute
Guillain-Barré syndromeGuillain-Barré syndrome
BBE is characterized by the rapid onset of ophthalmoplegia, ataxia, and disturbance of consciousness, and may be associated ... Fisher M (July 1956). "An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia ... ataxic hypersomnolence without ophthalmoplegia". J Neurol Neurosurg Psychiatry. 84 (11): 1206-7. doi:10.1136/jnnp-2013-304993. ...
https://en.wikipedia.org/wiki/Guillain–Barré_syndrome
Progressive supranuclear palsyProgressive supranuclear palsy
Richardson JC, Steele J, Olszewski J (1963). "Supranuclear Ophthalmoplegia, Pseudobulbar Palsy, Nuchal Dystonia and Dementia. A ...
https://en.wikipedia.org/wiki/Progressive_supranuclear_palsy
Multiple sclerosis signs and symptomsMultiple sclerosis signs and symptoms
Internuclear ophthalmoplegia is a disorder of conjugate lateral gaze. The affected eye shows impairment of adduction. The ... Menon GJ, Thaller VT (2002). "Therapeutic external ophthalmoplegia with bilateral retrobulbar botulinum toxin- an effective ... Internuclear ophthalmoplegia occurs when MS affects a part of the brain stem called the medial longitudinal fasciculus, which ...
https://en.wikipedia.org/wiki/Multiple_sclerosis_signs_and_symptoms
Machado-Joseph diseaseMachado-Joseph disease
MJD causes ophthalmoplegia and mixed sensory and cerebellar ataxia. Symptoms of MJD are memory deficits, spasticity, difficulty ...
https://en.wikipedia.org/wiki/Machado–Joseph_disease
Akinetic mutismAkinetic mutism
It is characterized by vertical gaze palsy and ophthalmoplegia. This state of akinetic mutism varies in intensity, but it is ...
https://en.wikipedia.org/wiki/Akinetic_mutism
Zenon MariakZenon Mariak
Mariak, Zenon; Mariak, Zofia; Lewko, J.; Łebkowski, Wojciech (September 15, 1992). "Internal ophthalmoplegia as a direct ...
https://en.wikipedia.org/wiki/Zenon_Mariak
Sensory ataxic neuropathy, dysarthria, and ophthalmoparesisSensory ataxic neuropathy, dysarthria, and ophthalmoparesis
"POLG mutations causing ophthalmoplegia, sensorimotor polyneuropathy, ataxia, and deafness". Neurology. 62 (2): 316-318. doi: ... presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia". ...
https://en.wikipedia.org/wiki/Sensory_ataxic_neuropathy,_dysarthria,_and_ophthalmoparesis
Mitochondrial neurogastrointestinal encephalopathy syndromeMitochondrial neurogastrointestinal encephalopathy syndrome
Ocular symptoms may include retinal degeneration, ophthalmoplegia, and ptosis. Those with MNGIE are often thin and experience ... It has been previously referred to as polyneuropathy, ophthalmoplegia, leukoencephalopathy, and POLIP syndrome. The disease ...
https://en.wikipedia.org/wiki/Mitochondrial_neurogastrointestinal_encephalopathy_syndrome
Recurrent painful ophthalmoplegic neuropathyRecurrent painful ophthalmoplegic neuropathy
Ophthalmoplegia usually occurs either concurrently or within 1 week after the onset of headache, and less commonly up to 2 ... Similar to headache, ophthalmoplegia usually resolve gradually and completely over time, but recovery may be incomplete after ... Therefore, it was postulated that migraine caused ophthalmoplegia in RPON. However, the major argument against a migrainous ... Depending on the severity of symptoms, various treatment options are available to people with persistent ophthalmoplegia. For ...
https://en.wikipedia.org/wiki/Recurrent_painful_ophthalmoplegic_neuropathy
Centronuclear myopathyCentronuclear myopathy
Involvement of the facial muscles may cause ophthalmoplegia or ptosis. A mutation in the RYR1 gene causing CNM may also cause ...
https://en.wikipedia.org/wiki/Centronuclear_myopathy
Idiopathic orbital inflammatory diseaseIdiopathic orbital inflammatory disease
Occasionally, ptosis, chemosis, motility dysfunction (ophthalmoplegia), and optic neuropathy are seen. In the setting of ...
https://en.wikipedia.org/wiki/Idiopathic_orbital_inflammatory_disease
Supranuclear ophthalmoplegia: MedlinePlus Medical EncyclopediaSupranuclear ophthalmoplegia: MedlinePlus Medical Encyclopedia
Supranuclear ophthalmoplegia is a condition that affects the movement of the eyes. ... supranuclear ophthalmoplegia; Whipple disease - supranuclear ophthalmoplegia; Dementia - supranuclear ophthalmoplegia ... Progressive supranuclear palsy - supranuclear ophthalmoplegia; Encephalitis - supranuclear ophthalmoplegia; ... People with supranuclear ophthalmoplegia are unable to move their eyes at will in all directions, especially looking upward. ...
https://medlineplus.gov/ency/article/001624.htm
A Young Woman With Painful Monocular OphthalmoplegiaA Young Woman With Painful Monocular Ophthalmoplegia
Cite this: A 36-Year-Old Woman With Painful Swelling and Ophthalmoplegia of the Right Eye - Medscape - Jun 11, 2014. ... A 36-Year-Old Woman With Painful Swelling and Ophthalmoplegia of the Right Eye ... A 36-Year-Old Woman With Painful Swelling and Ophthalmoplegia of the Right Eye. ... has complete external ophthalmoplegia with moderate proptosis. ...
https://reference.medscape.com/viewarticle/826346_5
Morphometric and biochemical study of muscle mitochondria in adult chronic progressive external ophthalmoplegia<...
Morphometric and biochemical study of muscle mitochondria in adult chronic progressive external ophthalmoplegia. In: Journal of ... Morphometric and biochemical study of muscle mitochondria in adult chronic progressive external ophthalmoplegia. Journal of ... Morphometric and biochemical study of muscle mitochondria in adult chronic progressive external ophthalmoplegia. / Federico, A ... title = "Morphometric and biochemical study of muscle mitochondria in adult chronic progressive external ophthalmoplegia", ...
https://moh-it.pure.elsevier.com/en/publications/morphometric-and-biochemical-study-of-muscle-mitochondria-in-adul
The Neuro-Ophthalmology of Multiple SclerosisThe Neuro-Ophthalmology of Multiple Sclerosis
Internuclear ophthalmoplegia *. Internuclear ophthalmoplegia is common in MS and results from damage to interneurons travelling ... Bilateral internuclear ophthalmoplegia in a patient with multiple sclerosis.. (A) In primary gaze, the patient has an exotropia ... Bilateral internuclear ophthalmoplegia in a patient with multiple sclerosis.. (A) In primary gaze, the patient has an exotropia ... Internuclear Ophthalmoplegia. INO is a horizontal gaze abnormality characterized by impaired adduction of the involved eye, ...
https://www.medscape.com/viewarticle/774939_4
IMSEAR at SEARO: Mitochondrial myopathy with chronic progressive external ophthalmoplegia.
Mitochondrial myopathy with chronic progressive external ophthalmoplegia.. Authors: Gunasekera, Harsha. Ranawaka, Udaya. ... Gunasekera H, Ranawaka U, Wijesekera J. Mitochondrial myopathy with chronic progressive external ophthalmoplegia. The Ceylon ...
https://imsear.searo.who.int/handle/123456789/48781
G.P.3.04 Autosomal dominant Progressive External Ophthalmoplegia (adPEO) due to mutations in the PEO1 gene: A clinical,...
G.P.3.04 Autosomal dominant Progressive External Ophthalmoplegia (adPEO) due to mutations in the PEO1 gene: A clinical, ... G.P.3.04 Autosomal dominant Progressive External Ophthalmoplegia (adPEO) due to mutations in the PEO1 gene: A clinical, ...
https://www.wrh.ox.ac.uk/publications/218840
Vertical Gaze Ophthalmoplegia and the Vascular Anatomy of the Midbrain and Diencephalon | Eccles Health Sciences Library | J....Vertical Gaze Ophthalmoplegia and the Vascular Anatomy of the Midbrain and Diencephalon | Eccles Health Sciences Library | J....
Since Parinauds description there have been numerous reports of vertical gaze ophthalmoplegia (VGO) and much has been learned ... Vertical Gaze Ophthalmoplegia; Vascular Anatomy; Midbrain; Diencephalon; Vertical Gaze Ophthalmoplegia; Posterior ... Vertical Gaze Ophthalmoplegia and the Vascular Anatomy of the Midbrain and Diencephalon. Download File , Share , Reference URL ... Since Parinauds description there have been numerous reports of vertical gaze ophthalmoplegia (VGO) and much has been learned ...
https://collections.lib.utah.edu/details?id=183586&facet_format_t=%22application%2Fpdf%22&facet_setname_s=%22ehsl_novel_nam%22&q=identifier_t%3A19860224_nanos_smoothpursuitsympos_07%2A&sort=facet_title_s+asc
Third nerve palsy versus internuclear ophthalmoplegia | NeurodiemThird nerve palsy versus internuclear ophthalmoplegia | Neurodiem
... describes how to differentiate internuclear ophthalmoplegia from third nerve palsy. ... Andrew Lee, MD, describes how to differentiate internuclear ophthalmoplegia from third nerve palsy. ...
https://www.neurodiem.dk/talk/third-nerve-palsy-versus-internuclear-ophthalmoplegia-s57NSSINp2BDZ2hanHv4H?locale=en-GB
Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021 | MMWRClinical Guidelines for Diagnosis and Treatment of Botulism, 2021 | MMWR
Facial paralysis, ophthalmoplegia, slurred speech, and inability to respond to requests because of muscle weakness might lead ... The most common signs were descending paralysis, ptosis, and ophthalmoplegia.. Signs and symptoms of botulism evolve over a ...
https://www.cdc.gov/mmwr/volumes/70/rr/rr7002a1.htm
Chronic Progressive External Ophthalmoplegia (CPEO) Treatment & Management: Approach Considerations, Medical Care, Surgical CareChronic Progressive External Ophthalmoplegia (CPEO) Treatment & Management: Approach Considerations, Medical Care, Surgical Care
Chronic progressive external ophthalmoplegia (CPEO) is a disorder characterized by slowly progressive paralysis of the ... encoded search term (Chronic Progressive External Ophthalmoplegia (CPEO)) and Chronic Progressive External Ophthalmoplegia ( ... Chronic Progressive External Ophthalmoplegia (CPEO) Treatment & Management. Updated: Mar 06, 2023 * Author: Michael Mercandetti ... Chronic Progressive External Ophthalmoplegia in the Absence of Ptosis. J Neuroophthalmol. 2016 Sep. 36 (3):270-4. [QxMD MEDLINE ...
https://emedicine.staging.medscape.com/article/1215103-treatment
What Are the Toxicological Effects of Ethylene Glycol Poisoning?What Are the Toxicological Effects of Ethylene Glycol Poisoning?
Ophthalmoplegia. *Visual disturbances. Such adverse effects are uncommon, but delayed treatment might contribute to their ...
https://www.atsdr.cdc.gov/csem/ethylene-propylene-glycol/toxicological_effects.html
The Lancet, 29 August 1891, Volume 138, Issue 3548 - Originally published as Volume 2, Issue 3548, Pages 473-524The Lancet, 29 August 1891, Volume 138, Issue 3548 - Originally published as Volume 2, Issue 3548, Pages 473-524
A CASE OF UNIOCULAR PROPTOSIS WITH INTRACRANIAL BRUIT AND OPHTHALMOPLEGIA; LIGATURE OF CAROTID;. RECOVERY. *G. Wherry ...
https://www.thelancet.com/journals/lancet/issue/vol138no3548/PIIS0140-6736
Table 4 - Potential Role of Deer Tick Virus in Powassan Encephalitis Cases in Lyme Disease-endemic Areas of New York, USA -...
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https://wwwnc.cdc.gov/eid/article/19/12/13-0903-t4
Benign food-borne type B botulism presenting as unilateral internal ophthalmoplegia: a case report. | BMC Neurol;22(1): 444,...Benign food-borne type B botulism presenting as unilateral internal ophthalmoplegia: a case report. | BMC Neurol;22(1): 444,...
Benign food-borne type B botulism presenting as unilateral internal ophthalmoplegia: a case report. ... Benign food-borne type B botulism presenting as unilateral internal ophthalmoplegia: a cas ... even in the case of unilateral/asymmetrical internal ophthalmoplegia without generalized progressive involvement of the ...
https://pesquisa.bvsalud.org/portal/resource/pt/mdl-36443684
Ophthalmoplastic Definition & Meaning | Merriam-Webster MedicalOphthalmoplastic Definition & Meaning | Merriam-Webster Medical
The meaning of OPHTHALMOPLASTIC is of or relating to plastic surgery of the eye or its adnexa. How to use ophthalmoplastic in a sentence.
https://www.merriam-webster.com/medical/ophthalmoplastic
Medical Definition of Kearns-Sayre syndromeMedical Definition of Kearns-Sayre syndrome
Ophthalmoplegia-plus syndrome; Ophthalmoplegia with myopathy; and Ophthalmoplegia with ragged-red fibers. ... Progressive paralysis of certain eye muscles (chronic progressive external ophthalmoplegia, or CPEO); *Abnormal accumulation of ...
https://www.medicinenet.com/kearns-sayre_syndrome/definition.htm
DeCS 2011 - December 22, 2011 versionDeCS 2011 - December 22, 2011 version
Ocular Muscular Dystrophy use Ophthalmoplegia, Chronic Progressive External Ocular Physiologic Processes use Ocular ...
https://decs.bvs.br/I/DeCS2011_Alfab-O.htm
DICER1 Tumor Predisposition - GeneReviews® - NCBI BookshelfDICER1 Tumor Predisposition - GeneReviews® - NCBI Bookshelf
Immediate clinical eval for signs/symptoms of (e.g.) cortisol excess (e.g., Cushing syndrome), ophthalmoplegia, strabismus, & ... ophthalmoplegia, and diabetes insipidus; ACTH levels are elevated in the majority of individuals [de Kock et al 2014a]. ...
https://www.ncbi.nlm.nih.gov/books/NBK196157/
Mitochondrial Myopathy - Neuromuscular DiseasesMitochondrial Myopathy - Neuromuscular Diseases
... and progressive external ophthalmoplegia (PEO).. The mitochondrial myopathies affect the mitochondria either through a defect ...
http://www.bellaonline.com/articles/art173556.asp
Chronic RhinosinusitisChronic Rhinosinusitis
Ophthalmoplegia *Meningisimus. VIII. Diagnosis *At least 12 consecutive weeks of findings AND ...
https://fpnotebook.com/ent/Sinus/ChrncRhnsnsts.htm
Cold Agglutinin Disease: Practice Essentials, Pathophysiology, EtiologyCold Agglutinin Disease: Practice Essentials, Pathophysiology, Etiology
Cold agglutinins are seen in CANOMAD syndrome (chronic ataxic neuropathy ophthalmoplegia M-protein agglutination disialosyl ... Delval A, Stojkovic T, Vermersch P. Relapsing sensorimotor neuropathy with ophthalmoplegia, antidisialosyl antibodies, and ... antibodies). This syndrome is described by gait and upper-limb ataxia; cranial nerve involvement with external ophthalmoplegia ...
https://emedicine.medscape.com/article/135327-overview
Eye Health Conditions | Case Definitions and Data Indicators | Project Description | Vision and Eye Health Surveillance System ...Eye Health Conditions | Case Definitions and Data Indicators | Project Description | Vision and Eye Health Surveillance System ...
... internal ophthalmoplegia, paresis of accommodation, or spasm of accommodation.. ...
https://www.cdc.gov/visionhealth/vehss/project/case-definitions-data/diagnosis.html
Third Cranial (Oculomotor) Nerve Disorders - Neurologic Disorders - Merck Manuals Professional EditionThird Cranial (Oculomotor) Nerve Disorders - Neurologic Disorders - Merck Manuals Professional Edition
Staff Profile - Faculty of Medical Sciences - Newcastle UniversityStaff Profile - Faculty of Medical Sciences - Newcastle University
Opening Ones Eyes to Mosaicism in Progressive External Ophthalmoplegia. Neurology Genetics 2017, 3(6), e202. ...
https://www.ncl.ac.uk/medical-sciences/people/profile/dougturnbull.html
Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish...Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish...
... in patients with progressive external ophthalmoplegia (PEO). Phenotypes other than PEO were recently documented in patients ...
https://pubmed.ncbi.nlm.nih.gov/16401742/
Articles by Bipasha Mukherjee : Indian Journal of OphthalmologyArticles by Bipasha Mukherjee : Indian Journal of Ophthalmology
Acute visual loss with ophthalmoplegia after spinal surgery: Report of a case and review of the literature. Mukherjee, Bipasha ...
https://journals.lww.com/ijo/pages/author.aspx?firstName=Bipasha&lastName=Mukherjee
KEGG ORTHOLOGY: K05863
Progressive external ophthalmoplegia. Brite. KEGG Orthology (KO) [BR:ko00001]. 09130 Environmental Information Processing. ...
https://www.genome.jp/dbget-bin/www_bget?ko:K05863
Encyclopedia of the Neurological Sciences - Elsevier Science & Technology - Literati by Credo
Ophthalmoplegia. *Opioids. *Oppenheim, Hermann. *Optical Coherence Tomography. *Optic Chiasm and Tract. *Optic Nerve (Cranial ...
https://corp.credoreference.com/component/booktracker/edition/9863.html
InternuclearChronic Progressive ExternalMitochondrialSyndromeProgressiveRagged-red fiEncephalomyopathyDiagnosisGazeRespiratorySymptomsIntellectualTypeTreatmentCaseMovementAtaxiaParalysisWeaknessPtosis and OphthalmoplegiaMyopathyNystagmusSymptomsDysarthriaSupranuclear ophthalmoplegiaCongenitalDeletionsOnsetDysfunctionHorizontalDeficits
Internuclear5
  • [ 100 ] The predominant abnormalities of efferent ocular function encountered in MS include internuclear ophthalmoplegia (INO), saccadic abnormalities, nystagmus, abnormalities of the vestibulo-ocular reflex (VOR) and smooth pursuit abnormalities. (medscape.com)
  • Bilateral internuclear ophthalmoplegia in a patient with multiple sclerosis. (medscape.com)
  • Andrew Lee, MD, describes how to differentiate internuclear ophthalmoplegia from third nerve palsy. (neurodiem.dk)
  • Lesion of the medial longitudinal fasciculus (MLF) resulting in internuclear ophthalmoplegia (INO). (medscape.com)
  • She had two relapses while on fingolimod including internuclear ophthalmoplegia in one instance and right hemihypesthesia in the other. (biomedcentral.com)
Chronic Progressive External6
  • IMSEAR at SEARO: Mitochondrial myopathy with chronic progressive external ophthalmoplegia. (who.int)
  • Gunasekera H, Ranawaka U, Wijesekera J. Mitochondrial myopathy with chronic progressive external ophthalmoplegia. (who.int)
  • For ptosis, adhesive tape and lid crutches can be used to assist patients with advanced chronic progressive external ophthalmoplegia (CPEO). (medscape.com)
  • It is imperative that patients with chronic progressive external ophthalmoplegia (CPEO) receive regularly scheduled follow-up care in all areas, especially with cardiology, as primary cardiac dysfunction can occur at any time. (medscape.com)
  • Available at https://eyewiki.aao.org/Chronic_Progressive_External_Ophthalmoplegia_(CPEO) . (medscape.com)
  • Neuropsychological testing of patients with chronic progressive external ophthalmoplegia and Kearns-Sayre Syndrome reveals distinct frontal and parieto-occipital deficits. (mpg.de)
Mitochondrial2
  • Both dominant and recessive mutations were reported in the gene encoding the mitochondrial (mt) DNA polymerase gamma (POLG) in patients with progressive external ophthalmoplegia (PEO). (nih.gov)
  • A mitochondrial DNA depletion syndrome that is characterized by onset in childhood or adulthood of progressive external ophthalmoplegia (PEO), muscle weakness and atrophy, exercise intolerance, and respiratory insufficiency due to muscle weakness, and has_material_basis_in autosomal recessive inheritance of homozygous mutation in the mitochondrial genome maintenance exonuclease 1 gene on chromosome 20p11. (zfin.org)
Syndrome1
  • Available at https://www.businesswire.com/news/home/20210104005195/en/Taysha-Gene-Therapies-Announces-Collaboration-with-AllStripes-on-SURF1-Associated-Leigh-Syndrome-Clinical-Development-and-Natural-History#:~:text=TSHA-104%20is%20an%20investigational%20AAV9-based%20 . (medscape.com)
Progressive3
  • The importance of what has been described here lies in underlining that it is always advisable to consider food -borne botulinum intoxication, even in the case of unilateral/asymmetrical internal ophthalmoplegia without generalized progressive involvement of the voluntary muscles . (bvsalud.org)
  • and progressive external ophthalmoplegia (PEO). (bellaonline.com)
  • Two patients had progressive external ophthalmoplegia, and one patient had vestibular dysfunction and ataxia. (molvis.org)
Ragged-red fi1
Encephalomyopathy1
  • Patient has encephalomyopathy, suprarenal insufficiency, ophthalmoplegia & mental retardation. (mitomap.org)
Diagnosis1
  • Re: Help me diagnosis cause of ophthalmoplegia an. (curezone.org)
Gaze1
  • Since Parinaud's description there have been numerous reports of vertical gaze ophthalmoplegia (VGO) and much has been learned about the physiology of vertical gaze. (utah.edu)
Respiratory2
  • Systemic toxicity includes neurotoxic cases of envenomation, with 81 410-137 880 deaths each symptoms such as ptosis, ophthalmoplegia, respiratory year worldwide ( 1 , 2 ). (who.int)
  • Systemic toxicity includes neurotoxic symptoms such as ptosis, ophthalmoplegia, respiratory failure and paralysis (9). (who.int)
Symptoms1
  • Treatment depends on the cause and symptoms of the supranuclear ophthalmoplegia. (medlineplus.gov)
Intellectual1
  • A rare X-linked syndromic intellectual disability characterized by intellectual deficit, growth retardation with short stature, deafness and ophthalmoplegia. (orpha.net)
Type1
  • Benign food-borne type B botulism presenting as unilateral internal ophthalmoplegia: a case report. (bvsalud.org)
Treatment1
  • 2021 · цитируется: 2 - the role of systemic steroids in the treatment of ophthalmoplegia in the setting of herpes zoster ophthalmicus (hzo) is controversial. (billybauerband.com)
Case2
  • We report a case of herpes zoster ophthalmicus-related ophthalmoplegia (hzoro) in which systemic steroid led to complete resolution of external. (billybauerband.com)
  • Method: we report a case of herpes zoster ophthalmicus-related ophthalmoplegia (hzoro) in which. (billybauerband.com)
Movement1
  • Supranuclear ophthalmoplegia is a condition that affects the movement of the eyes. (medlineplus.gov)
Ataxia7
  • Female patient presents respiratory infection 1 month before the appearance of following triad: ophthalmoplegia, ataxia, and hyporeflexia. (scielo.org.mx)
  • This diagnosis was based on a neurological examination that permitted identifying the classic triad consisting of acute ophthalmoplegia, areflexia, and ataxia, not responsive to immunotherapy treatment and with progression to a classic GBS. (scielo.org.mx)
  • These include Leber hereditary optic neuropathy (LHON), mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes (MELAS), Kearns-Sayre syndrome (KSS), Pearson syndrome, progressive external ophthalmoplegia (PEO), neuropathy ataxia retinitis pigmentosia (NARP), myoclonus epilepsy with ragged red fibers (MERRF) and Leigh syndrome. (seattlechildrens.org)
  • They include myocerebrohepatopathy spectrum (MCHS) disorders, Alpers-Huttenlocher syndrome, myoclonus epilepsy myopathy and sensory ataxia (MEMSA) and autosomal recessive and dominant progressive external ophthalmoplegia (PEO). (seattlechildrens.org)
  • Sensorineural deafness along with other extra-ocular manifestations may appear, such as chronic progressive external ophthalmoplegia , proximal myopathy , ataxia and axonal sensory motor polyneuropathy beginning in the second to third decades of life. (adoaa.org)
  • Wernicke Encephalopathy Wernicke encephalopathy is characterized by acute onset of confusion, nystagmus, partial ophthalmoplegia, and ataxia due to thiamin deficiency. (merckmanuals.com)
  • Dosage & schedule of administration include guillain-barr syndrome miller-fisher variant ataxia, areflexia, ophthalmoplegia, weakness is present, mg tolazoline may be required include angiography to be as acute coronary ischemia, usually in the filtrate or dialysate, and the duration of stay and resource use, and identification of stenoses of the entire adrenal gland is destroyed and thyroid see figure athis refers to a reduction of about bpm. (aaan.org)
Paralysis4
  • Signs and symptoms tend to begin in early adulthood and most commonly include weakness or paralysis of the muscles that move the eye (ophthalmoplegia) and drooping of the eyelids (ptosis). (nih.gov)
  • PEO is characterized by ptosis, impaired eye movements due to paralysis of the extraocular muscles (ophthalmoplegia), oropharyngeal weakness, and variably severe proximal limb weakness with exercise intolerance. (nih.gov)
  • Systemic toxicity includes neurotoxic symptoms such as ptosis, ophthalmoplegia, respiratory failure and paralysis (9). (who.int)
  • Sauvineau ophthalmoplegia - ocular muscle paralysis caused by a lesion in the medial longitudinal fasciculus. (thefreedictionary.com)
Weakness2
  • Weakness can also affect the muscles of the face and muscles that control eye movement (ophthalmoplegia), sometimes causing droopy eyelids ( ptosis ). (medlineplus.gov)
  • In one of the six cases, TGen researchers found a unique disease-causing variant, or mutation, in the CACNA1S gene for a child with severe muscle weakness in addition to ophthalmoplegia, or the inability to move his eyes. (azbio.org)
Ptosis and Ophthalmoplegia2
  • Fig. 1 Picture of patient exhibiting bilateral ptosis and ophthalmoplegia at the time of admission. (ablkinase.com)
  • 11 In this retrospective study, his research group reported 256 cases of new-onset diplopia, ptosis and ophthalmoplegia within eight months following statin administration. (reviewofoptometry.com)
Myopathy3
  • Short-chain acyl-CoA dehydrogenase deficiency: a cause of ophthalmoplegia and multicore myopathy. (harvard.edu)
  • To our knowledge, this is the first reported case of severe congenital myopathy with ophthalmoplegia resulting from pathogenic variants in CACNA1S ," said Dr. Jesse Hunter, a TGen Senior Post-Doctoral Fellow, and the study's lead author. (azbio.org)
  • It is a mitochondrial myopathy characterized by ophthalmoplegia, retinitis pigmentosa, and cardiac defects. (picmonic.com)
Nystagmus2
  • [1] Neuro-ophthalmologic findings have also been reported in patients with AGA, including findings of retinopathy, ophthalmoplegia and diplopia, cerebellar ocular dysfunction, and nystagmus. (aao.org)
  • Forty-six (81%) of the patients had one or more ophthalmological findings such as ptosis (n = 16), reduced eye motility (n = 22) including severe external ophthalmoplegia (n = 9), strabismus (n = 4), nystagmus (n = 9), low VA (n = 21), refractive errors (n = 26), photophobia (n = 4), and partial or total optic atrophy (n = 25). (bmj.com)
Symptoms2
  • In March 2011, the patient complained of mild pain in left eye, moderate periorbital swelling, and ophthalmoplegia without other neurological symptoms. (hindawi.com)
  • Systemic toxicity includes neurotoxic cases of envenomation, with 81 410-137 880 deaths each symptoms such as ptosis, ophthalmoplegia, respiratory year worldwide ( 1 , 2 ). (who.int)
Dysarthria1
  • Since then, multiple point variants of mtDNA and nuclear genes have been identified to cause mitochondrial PEO and PEO-plus syndromes, including mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) and sensory ataxic neuropathy dysarthria ophthalmoplegia (SANDO). (nih.gov)
Supranuclear ophthalmoplegia4
  • An 85-year-old man developed l-dopa responsive parkinsonism indistinguishable from Parkinson's disease and subsequent dementia, followed by supranuclear ophthalmoplegia and neck dorsiflexion at the terminal stage. (iospress.com)
  • Supranuclear ophthalmoplegia is a condition that affects the movement of the eyes. (healthmedicinet.com)
  • A brain injury (such as stroke ) also can cause supranuclear ophthalmoplegia. (healthmedicinet.com)
  • The treatment depends on the cause of the supranuclear ophthalmoplegia. (healthmedicinet.com)
Congenital1
  • Strabismus and ophthalmoplegia are The congenital myasthenic syndromes are genetically and clinically heterogeneous. (webhelpusa.com)
Deletions1
  • Unlike many syndromes of external ophthalmoplegia with deletions in mitochondria, no nuclear DNA mutations have been associated with this disorder. (arizona.edu)
Onset2
  • The subpopulation of patients with long-standing TPPV showed ophthalmoplegia, while its appearance rate was less in the patients with an older age at onset than in those with a younger age at onset. (elsevier.com)
  • We describe a case orbital infection caused by Scopulariopsis in a patient with uncontrolled diabetes who presented with acute onset of unilateral painful ophthalmoplegia, defective vision and drooping of eyelid. (ijmedicine.com)
Dysfunction1
  • Clinical improvement of her ophthalmoplegia and of neurological dysfunction of the upper extremities was noted after prompt and aggressive treatment with intravenous pulsed methylprednisolone and cyclophosphamide. (koreamed.org)
Horizontal1
  • A patient positive for AGA and a mixed-type thymoma was found to have almost complete bilateral ophthalmoplegia for horizontal and upward ocular movements. (aao.org)
Deficits1