A genus of parasitic nematodes whose organisms live and breed in skin and subcutaneous tissues. Onchocercal microfilariae may also be found in the urine, blood, or sputum.
A species of parasitic nematodes widely distributed throughout central Africa and also found in northern South America, southern Mexico, and Guatemala. Its intermediate host and vector is the blackfly or buffalo gnat.
Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
Several species of the genus Simulium (family Simuliidae) that act as intermediate hosts (vectors) for the parasitic disease ONCHOCERCIASIS.
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
The prelarval stage of Filarioidea in the blood and other tissues of mammals and birds. They are removed from these hosts by blood-sucking insects in which they metamorphose into mature larvae.
Any part or derivative of a helminth that elicits an immune reaction. The most commonly seen helminth antigens are those of the schistosomes.
Pharmacological agents destructive to nematodes in the superfamily Filarioidea.
Deoxyribonucleic acid that makes up the genetic material of helminths.
Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.
Skin diseases caused by ARTHROPODS; HELMINTHS; or other parasites.
Immunoglobulins produced in a response to HELMINTH ANTIGENS.
A genus of parasitic nematodes found throughout the rain-forest areas of the Sudan and the basin of the Congo. L. loa inhabits the subcutaneous tissues, which it traverses freely.
A republic in central Africa lying east of CHAD and the CENTRAL AFRICAN REPUBLIC and west of NIGERIA. The capital is Yaounde.
Proteins found in any species of helminth.
A superfamily of nematodes of the suborder SPIRURINA. Its organisms possess a filiform body and a mouth surrounded by papillae.
A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984)
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Drugs used to treat or prevent parasitic infections.
Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
A genus of parasitic nematodes whose organisms are distributed in Central and South America. Characteristics include a smooth cuticle and an enlarged anterior end.
A filarial nematode parasite of mammalian blood with the vector being a tick or small fly.
A republic in western Africa, lying between GHANA on its west and BENIN on its east. Its capital is Lome.
A parasitic infection caused by the nematode Loa loa. The vector in the transmission of this infection is the horsefly (Tabanus) or the deerfly or mango fly (Chrysops). The larvae may be seen just beneath the skin or passing through the conjunctiva. Eye lesions are not uncommon. The disease is generally mild and painless.
A genus of filarial nematodes. Various immature species have been found to infect the eyes or subcutaneous tissue in humans.
Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
I'm sorry for any confusion, but "Guatemala" is not a medical term and does not have a medical definition. Guatemala is the name of a country located in Central America, known officially as the Republic of Guatemala. If you have any questions related to medical topics or definitions, I would be happy to help with those!
Inflammation of the cornea.
Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
I'm sorry for any confusion, but "Ecuador" is a country in South America and not a medical term. The term you might be looking for is "ecdysone," which is a hormone found in arthropods that controls their molting process.
A TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.
A republic in western Africa, south of GUINEA and east of COTE D'IVOIRE. Its capital is Monrovia.
A species of parasitic nematode causing Malayan filariasis and having a distribution centering roughly on the Malay peninsula. The life cycle of B. malayi is similar to that of WUCHERERIA BANCROFTI, except that in most areas the principal mosquito vectors belong to the genus Mansonia.
Insects that transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.
A republic in western Africa, south of SENEGAL and MALI, east of GUINEA-BISSAU. Its capital is Conakry.
A plant family of the order Magnoliales, subclass Magnoliidae, class Magnoliopsida. They are trees and shrubs having an elongated conelike floral axis with fragrant flowers that have six tepals (sepals and petals that are not distinctly different) and many spirally arranged stamens.
A white threadlike worm which causes elephantiasis, lymphangitis, and chyluria by interfering with the lymphatic circulation. The microfilaria are found in the circulating blood and are carried by mosquitoes.
A genus of parasitic nematodes found in the peritoneal cavity of wild or domestic cattle or equines.
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
The geographical area of Africa comprising BENIN; BURKINA FASO; COTE D'IVOIRE; GAMBIA; GHANA; GUINEA; GUINEA-BISSAU; LIBERIA; MALI; MAURITANIA; NIGER; NIGERIA; SENEGAL; SIERRA LEONE; and TOGO.
Inflammation of the choroid in which the sensory retina becomes edematous and opaque. The inflammatory cells and exudate may burst through the sensory retina to cloud the vitreous body.
The reduction or regulation of the population of noxious, destructive, or dangerous insects through chemical, biological, or other means.
Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.

Pathogenesis of onchocercal keratitis (River blindness). (1/97)

Onchocerciasis is a major cause of blindness. Although the World Health Organization has been successful in reducing onchocerciasis as a public health problem in parts of West Africa, there remain an estimated 17 million people infected with Onchocerca volvulus, the parasite that causes this disease. Ocular pathology can be manifested in any part of the eye, although disease manifestations are frequently characterized as either posterior or anterior eye disease. This review focuses on onchocerca-mediated keratitis that results from an inflammatory response in the anterior portion of the eye and summarizes what is currently known about human disease. This review also describes studies with experimental models that have been established to determine the immunological mechanisms underlying interstitial keratitis. The pathogenesis of keratitis is thought to be due to the host inflammatory response to degenerating parasites in the eye; therefore, the primary clinical symptoms of onchocercal keratitis (corneal opacification and neovascularization) are induced after injection of soluble O. volvulus antigens into the corneal stroma. Experimental approaches have demonstrated an essential role for sensitized T helper cells and shown that cytokines can regulate the severity of keratitis by controlling recruitment of inflammatory cells into the cornea. Chemokines are also important in inflammatory cell recruitment to the cornea, and their role in onchocerciasis is being examined. Further understanding of the molecular basis of the development of onchocercal keratitis may lead to novel approaches to immunologically based intervention.  (+info)

A new technique for the determination of microfilarial densities in onchocerciasis. (2/97)

Precise measurement of the parasite load in helminthic infections makes it possible to correlate morbidity, the individual response to treatment, and the best control methods. A membrane filtration technique was recently developed for quantifying Wuchereria bancrofti microfilaraemia. The present paper describes its application to onchocerciasis in a study on 107 patients in northern Togo. The technique is cheap and simple to apply under field conditions, and is extremely efficient at recovering microfilariae from skin snips.  (+info)

Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship. (3/97)

Filarial nematodes are important and widespread parasites of animals and humans. We have been using the African bovine parasite Onchocerca ochengi as a chemotherapeutic model for O. volvulus, the causal organism of 'river blindness' in humans, for which there is no safe and effective drug lethal to adult worms. Here we report that the antibiotic, oxytetracycline is macrofilaricidal against O. ochengi. In a controlled trial in Cameroon, all adult worms (as well as microfilariae) were killed, and O. ochengi intradermal nodules resolved, by nine months' post-treatment in cattle treated intermittently for six months. Adult worms removed from concurrent controls remained fully viable and reproductively active. By serial electron-microscopic examination, the macrofilaricidal effects were related to the elimination of intracellular micro-organisms, initially abundant. Analysis of a fragment of the 16S rRNA gene from the O. ochengi micro-organisms confirmed them to be Wolbachia organisms of the order Rickettsiales, and showed that the sequence differed in only one nucleotide in 858 from the homologous sequence of the Wolbachia organisms of O. volvulus. These data are, to our knowledge, the first to show that antibiotic therapy can be lethal to adult filariae. They suggest that tetracycline therapy is likely to be macrofilaricidal against O. volvulus infections in humans and, since similar Wolbachia organisms occur in a number of other filarial nematodes, against those infections too. In that the elimination of Wolbachia preceded the resolution of the filarial infections, they suggest that in O. ochengi at least, the Wolbachia organisms play an essential role in the biology and metabolism of the filarial worm.  (+info)

Onchocerca ochengi transmission dynamics and the correlation of O. ochengi microfilaria density in cattle with the transmission potential. (4/97)

The intensity of natural transmission of Onchocerca ochengi and Onchocerco volvulus by anthropo-boophilic Simulium damnosum s.l. was studied longitudinally in two cattle watering sites of a cattle ranch within a predominantly cattle populated area of the Guinea savanna of Cameroon and related to cattle O. ochengi skin microfilaria abundance. During the 12 months study period, a total of 4696 flies was individually dissected to examine the monthly transmission potential (MTP) of O. ochengi and O. volvulus. The estimated Simulium damnosum s.l. annual biting rates (ABR) on human baits were 47529 flies at the bank of the Vina "du sud" river. The ABR at the lake, which was situated at about 2 km upland from the perennial river, was 8579. The monthly parous rate was highly correlated with monthly biting rate. The annual transmission potentials (ATP) of O. ochengi were calculated to be 7732 and 1669 at the riverbank and the lake, respectively. Transmission occurred mainly in the dry season, peaking in the months of January to mid-March when dermal microfilaria density in the animals was also the highest. The O. ochengi microfilaria uptake by the fly vectors was host microfilaria density-dependent. The MTP of O. ochengi was positively correlated with dermal microfilaria density. The mean number of microfilariae per fly taken up during a blood meal was high during the dry season as was the mean number of infective larvae per fly but declined significantly with the onset of the early rains. A similar seasonality of transmission was also observed for O. volvulus that was concurrently transmitted by the same vector flies, but its ATP was comparatively much lower: 1332 infective larvae per man per year at the riverbank and 107 around the lake. The population dynamics of cattle microfilariae therefore plays an important role in the regulation of O. ochengi transmission.  (+info)

Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis. (5/97)

Onchocerciasis is a debilitating parasitic infection caused by the filarial nematode Onchocerca volvulus. Infections are chronic, and persistence of the parasites for several years argues for highly adapted mechanisms of immune evasion. Due to the restricted host repertoire of O. volvulus, we have used the cattle parasite Onchocerca ochengi to investigate the nature of immunomodulation underpinning these long-term infections. Cattle were infected with a single inoculation of 350 infective-stage larvae under laboratory conditions (n = 6). Intradermal nodules containing immature adult worms were detected from 110 days postinfection, and microfilariae in skin were detected from day 280 postinfection. Parasite-specific responses during early infection were nonpolarized with respect to the major Th cytokines (interleukin-4 [IL-4], IL-2, and gamma interferon [IFN-gamma]) produced by antigen-stimulated peripheral blood mononuclear cells (PBMC) or serum antibody isotypes. Antigen-induced proliferation of PBMC peaked shortly after exposure and remained high during the prepatent infection. As the parasites matured and animals developed patent infections, there was a profound down-regulation of lymphoproliferation, accompanied by sharp falls in the expression of both IL-4 and IFN-gamma and a gradual decline in IL-2. Levels of immunoglobulin G2 (IgG2) fell, while those of IgG1 remained high. We conclude that neither a classical Th2 response nor a simple Th1-to-Th2 switch is sufficient to explain the immunomodulation associated with patent Onchocerca infections. Instead, there is an initial Th0 response, which matures into a response with some, but not all of the features of a Th2 response. The natural host-parasite relationship of O. ochengi in cattle may be useful as both a descriptive and predictive tool to test more refined models of immunomodulation in onchocerciasis.  (+info)

Expression and secretion of a larval-specific chitinase (family 18 glycosyl hydrolase) by the infective stages of the parasitic nematode, Onchocerca volvulus. (6/97)

A recently reported chitinase gene, expressed in the infective, third-stage (L3) larvae of the human filarial parasite Onchocerca volvulus, belongs to the family 18 glycosyl hydrolases and has been designated Ov-chi-1. The gene product of Ov-chi-1 is chitinolytic. Allosamidin ablates activity of the native enzyme in a dose-dependent manner but did not significantly inhibit the moulting of L3 larvae. Mono-specific antibodies were used to characterize Ov-CHI-1 as a 60-kDa protein expressed almost exclusively in L3 stages. Immunoelectron microscopy showed that Ov-CHI-1 expression is initiated in late L2 larvae and increases markedly in infective, L3 larvae. It is synthesized exclusively in the glandular esophagus and stored within discrete secretory granules. Secretion occurs through de-granulation during post-infective development, and the primary route of transport appears to be via the pseudo-coelom. An orthologue of Ov-chi-1 was detected in Caenorhabditis elegans by BLAST analysis. It is constitutively expressed at a low level and is overexpressed in dauer larvae and embryonated eggs. It is chitinolytic. We conclude that Ov-CHI-1 is a highly stage-specific enzyme that may have a role in infectivity of the parasite, aiding escape from the vector or participating in early post-infective migration and/or development. The identification of an orthologue in C. elegans opens the way for further studies into the biological function(s) of this intriguing parasite product.  (+info)

Community-based ivermectin therapy for onchocerciasis: comparison of three methods of dose assessment. (7/97)

A new method of assessment based on mid-upper arm circumference (MUAC) is described for dosage adjustment for community-based ivermectin distribution. We studied 878 subjects eligible for ivermectin dosing in Awhum, Nigeria. In a previous preliminary study of 40 persons, MUAC (in cm) correlated with weight (kg) in the first 20 male (r = 0.97, r2 = 0.95, P < 0.0001) and the first 20 female subjects (r = 0.94, r2 = 0.88, P < 0.0001). We therefore studied the use of height, physical appearance, and MUAC for calculating the dose of ivermectin. The MUAC-based schedule underdosed only 4.1% of the population. The methods based on height underdosed 3.3% and 21.1%, and assignment based on physical appearance underdosed 10.2% of the population studied. This MUAC-based method (13-15 cm, 0.5 tablet; 16-20 cm, 1.0 tablet; 21-27 cm, 1.5 tablets; > or = 28 cm, 2.0 tablets) is more convenient and corresponds closely to dosing by weight. An adaptation of this method with reference to other prevalent tropical diseases and their respective drugs is therefore advocated.  (+info)

Sensitive and specific serodiagnosis of onchocerciasis with recombinant hybrid proteins. (8/97)

Onchocerciasis remains a major health hazard in many tropical countries. However, the existing tools for diagnosis of the disease have limitations, particularly regarding the detection of low level or early infections. To design an optimized reagent, we exploited the high antibody reactivity of patient sera against the Onchocerca volvulus proteins Ov20 and Ov33, which have been described as highly sensitive and specific immunodiagnostic reagents for producing hybrid proteins. The construct OvH2 was composed of Ov20 fused to Ov33, while OvH3 consisted of the C-terminus of Ov20 linked to Ov33. When these constructs were tested with sera from patients with onchocerciasis and control sera, OvH2 showed a sensitivity of 98.5% and a specificity of 97.7% and OvH3 showed a sensitivity of 98.5% and a specificity of 95.35%. All non-responders were from Ecuador. These results surpass those of existing single recombinant antigens, suggesting that our hybrid proteins combined the sensitivity of the two parent proteins. Tests based on OvH2 should prove suitable for monitoring onchocerciasis control programs and individual diagnosis.  (+info)

Onchocerca is a genus of filarial nematode worms that are the causative agents of onchocerciasis, also known as river blindness. The most common species to infect humans is Onchocerca volvulus. These parasites are transmitted through the bite of infected blackflies (Simulium spp.) that breed in fast-flowing rivers and streams.

The adult female worms live in nodules beneath the skin, while the microfilariae, which are released by the females, migrate throughout various tissues, including the eyes, where they can cause inflammation and scarring, potentially leading to blindness if left untreated. The infection is primarily found in Africa, with some foci in Central and South America. Onchocerciasis is considered a neglected tropical disease by the World Health Organization (WHO).

'Onchocerca volvulus' is a species of parasitic roundworm that is the causative agent of human river blindness, also known as onchocerciasis. This disease is named after the fact that the larval forms of the worm are often found in the rivers and streams where the blackfly vectors breed.

The adult female worms measure about 33-50 cm in length and live in nodules beneath the skin, while the much smaller males (about 4 cm long) move between the nodules. The females release microfilariae, which are taken up by blackflies when they bite an infected person. These larvae then develop into infective stages within the blackfly and can be transmitted to another human host during a subsequent blood meal.

The infection leads to various symptoms, including itchy skin, rashes, bumps under the skin (nodules), and in severe cases, visual impairment or blindness due to damage caused to the eyes by the migrating larvae. The disease is prevalent in certain regions of Africa, Latin America, and Yemen. Preventive measures include avoiding blackfly bites, mass drug administration with anti-parasitic drugs, and vector control strategies.

Onchocerciasis is a neglected tropical disease caused by the parasitic worm Onchocerca volvulus. The infection is primarily transmitted through the bites of infected blackflies (Simulium spp.) that breed in fast-flowing rivers and streams. The larvae of the worms mature into adults in nodules under the skin, where females release microfilariae that migrate throughout the body, including the eyes.

Symptoms include severe itching, dermatitis, depigmentation, thickening and scarring of the skin, visual impairment, and blindness. The disease is also known as river blindness due to its association with riverside communities where blackflies breed. Onchocerciasis can lead to significant social and economic consequences for affected individuals and communities. Preventive chemotherapy using mass drug administration of ivermectin is the primary strategy for controlling onchocerciasis in endemic areas.

Simuliidae is a family of small, robust two-winged flies known as black flies or buffalo gnats. The term "Simuliidae" itself is the taxonomic name for this group of insects. They are called black flies because many species are dark in color, and they are often referred to as gnats or buffalo gnats due to their small size and annoying biting behavior.

Black flies are well-known for their medical significance, as they can transmit several diseases to humans and animals, including onchocerciasis (river blindness), leucocytozoonosis, and various forms of bacterial infections. The female black flies feed on blood from hosts, while males primarily feed on nectar.

These insects are typically found near bodies of water, where their larvae develop in flowing or standing waters with high oxygen levels. They have aquatic habits and undergo a complete metamorphosis during their life cycle, transforming from an egg to larva, then pupa, and finally into an adult fly.

In summary, Simuliidae is the medical term for black flies or buffalo gnats, which are small, robust two-winged flies with a medical significance due to their ability to transmit diseases to humans and animals.

Ivermectin is an anti-parasitic drug that is used to treat a variety of infections caused by parasites such as roundworms, threadworms, and lice. It works by paralyzing and killing the parasites, thereby eliminating the infection. Ivermectin is available in various forms, including tablets, creams, and solutions for topical use, as well as injections for veterinary use.

Ivermectin has been shown to be effective against a wide range of parasitic infections, including onchocerciasis (river blindness), strongyloidiasis, scabies, and lice infestations. It is also being studied as a potential treatment for other conditions, such as COVID-19, although its effectiveness for this use has not been proven.

Ivermectin is generally considered safe when used as directed, but it can cause side effects in some people, including skin rashes, nausea, and diarrhea. It should be used with caution in pregnant women and people with certain medical conditions, such as liver or kidney disease.

Microfilaria is the larval form of certain parasitic roundworms (nematodes) belonging to the family Onchocercidae. These worms include species that cause filariasis, which are diseases transmitted through the bite of infected mosquitoes or blackflies. The microfilariae are found in the blood or tissue fluids of the host and can measure from 200 to 300 microns in length. They have a distinct sheath and a characteristic tail taper, which helps in their identification under a microscope. Different filarial species have specific microfilariae characteristics, such as size, shape, and lifestyle patterns (nocturnal or diurnal periodicity). The presence of microfilariae in the host's blood or tissue fluids is indicative of an ongoing infection with the respective filarial parasite.

Helminth antigens refer to the proteins or other molecules found on the surface or within helminth parasites that can stimulate an immune response in a host organism. Helminths are large, multicellular parasitic worms that can infect various tissues and organs in humans and animals, causing diseases such as schistosomiasis, lymphatic filariasis, and soil-transmitted helminthiases.

Helminth antigens can be recognized by the host's immune system as foreign invaders, leading to the activation of various immune cells and the production of antibodies. However, many helminths have evolved mechanisms to evade or suppress the host's immune response, allowing them to establish long-term infections.

Studying helminth antigens is important for understanding the immunology of helminth infections and developing new strategies for diagnosis, treatment, and prevention. Some researchers have also explored the potential therapeutic use of helminth antigens or whole helminths as a way to modulate the immune system and treat autoimmune diseases or allergies. However, more research is needed to determine the safety and efficacy of these approaches.

Filaricides are a type of medication used to treat infections caused by filarial worms, which are parasitic roundworms that can infect humans and animals. These medications work by killing or inhibiting the development of the larval stages of the worms, thereby helping to eliminate the infection and prevent further transmission.

Filaricides are often used to treat diseases such as onchocerciasis (river blindness), lymphatic filariasis (elephantiasis), and loiasis (African eye worm). Examples of filaricides include ivermectin, diethylcarbamazine, and albendazole. It is important to note that these medications should only be used under the guidance of a healthcare professional, as they can have serious side effects if not used properly.

Helminth DNA refers to the genetic material found in parasitic worms that belong to the phylum Platyhelminthes (flatworms) and Nematoda (roundworms). These parasites can infect various organs and tissues of humans and animals, causing a range of diseases.

Helminths have complex life cycles involving multiple developmental stages and hosts. The study of their DNA has provided valuable insights into their evolutionary history, genetic diversity, and mechanisms of pathogenesis. It has also facilitated the development of molecular diagnostic tools for identifying and monitoring helminth infections.

Understanding the genetic makeup of these parasites is crucial for developing effective control strategies, including drug discovery, vaccine development, and disease management.

Mansonelliasis is a parasitic infection caused by the nematode (roundworm) species Mansonella perstans, M. ozzardi, or M. streptocerca. These parasites are transmitted to humans through the bite of infected blackflies or midges. The infection can cause a range of symptoms including fever, headache, pruritus (severe itching), and rash. In some cases, there may be no symptoms at all. Chronic infections can lead to more serious complications such as endocarditis, hepatomegaly (enlarged liver), and splenomegaly (enlarged spleen). However, mansonelliasis is often overlooked or misdiagnosed due to its nonspecific symptoms and the limited availability of diagnostic tests.

Parasitic skin diseases are conditions caused by parasites living on or in the skin. These parasites can be insects, mites, or fungi that feed off of the host for their own survival. They can cause a variety of symptoms including itching, rashes, blisters, and lesions on the skin. Examples of parasitic skin diseases include scabies, lice infestations, and ringworm. Treatment typically involves the use of topical or oral medications to kill the parasites and alleviate symptoms.

Antibodies are proteins produced by the immune system in response to the presence of a foreign substance, known as an antigen. They are capable of recognizing and binding to specific antigens, neutralizing or marking them for destruction by other immune cells.

Helminths are parasitic worms that can infect humans and animals. They include roundworms, tapeworms, and flukes, among others. Helminth infections can cause a range of symptoms, depending on the type of worm and the location of the infection.

Antibodies to helminths are produced by the immune system in response to an infection with one of these parasitic worms. These antibodies can be detected in the blood and serve as evidence of a current or past infection. They may also play a role in protecting against future infections with the same type of worm.

There are several different classes of antibodies, including IgA, IgD, IgE, IgG, and IgM. Antibodies to helminths are typically of the IgE class, which are associated with allergic reactions and the defense against parasites. IgE antibodies can bind to mast cells and basophils, triggering the release of histamine and other inflammatory mediators that help to protect against the worm.

In addition to IgE, other classes of antibodies may also be produced in response to a helminth infection. For example, IgG antibodies may be produced later in the course of the infection and can provide long-term immunity to reinfection. IgA antibodies may also be produced and can help to prevent the attachment and entry of the worm into the body.

Overall, the production of antibodies to helminths is an important part of the immune response to these parasitic worms. However, in some cases, the presence of these antibodies may also be associated with allergic reactions or other immunological disorders.

"Loa" is a term used in tropical medicine, specifically in the context of parasitic diseases. It refers to a type of filarial worm that can infect humans and cause a disease known as loiasis (also called "loa loa" or "African eye worm"). The Loa loa parasite is transmitted to humans through the bite of deerfly or mango fly, which acts as a vector.

The adult Loa loa worms typically reside in the subcutaneous tissue of the human host, where they can cause various symptoms such as localized itching, skin rashes, and arthralgias (joint pain). The parasite is also known to migrate through various tissues, including the eye, which can result in the appearance of a visible, moving worm under the conjunctiva. This is how loiasis earned its colloquial name "African eye worm."

Loiasis is primarily found in the rainforest regions of West and Central Africa. While not typically life-threatening on its own, loiasis can complicate the treatment of other filarial diseases such as onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis), due to potential adverse reactions to the medications used to treat these conditions.

I'm not aware of any medical condition or term that is specifically associated with or referred to as "Cameroon." Cameroon is a country located in Central Africa, known for its rich biodiversity and cultural diversity. If you have more context about why you are looking for a medical definition of "Cameroon," I may be able to provide a more helpful response.

Helminth proteins refer to the proteins that are produced and expressed by helminths, which are parasitic worms that cause diseases in humans and animals. These proteins can be found on the surface or inside the helminths and play various roles in their biology, such as in development, reproduction, and immune evasion. Some helminth proteins have been identified as potential targets for vaccines or drug development, as blocking their function may help to control or eliminate helminth infections. Examples of helminth proteins that have been studied include the antigen Bm86 from the cattle tick Boophilus microplus, and the tetraspanin protein Sm22.6 from the blood fluke Schistosoma mansoni.

Filarioidea is a superfamily of parasitic nematode (roundworm) worms, many of which are important pathogens in humans and animals. They are transmitted to their hosts through the bite of insect vectors, such as mosquitoes or flies. The filarioid worms can cause a range of diseases known as filariases. Some examples include Wuchereria bancrofti, Brugia malayi, and Onchocerca volvulus, which cause lymphatic filariasis (elephantiasis) and river blindness, respectively. The adult worms live in the lymphatic system or subcutaneous tissues of their hosts, where they produce microfilariae, the infective stage for the insect vector.

The medical definition of Filarioidea is: A superfamily of parasitic nematode worms that includes several important human pathogens and causes various filariases. The adult worms live in the lymphatic system or subcutaneous tissues, while the microfilariae are taken up by insect vectors during a blood meal and develop into infective larvae inside the vector. These larvae are then transmitted to a new host through the bite of the infected vector.

Wolbachia is a genus of intracellular bacteria that naturally infects a wide variety of arthropods (insects, spiders, mites) and filarial nematodes (roundworms). These bacteria are transmitted vertically from mother to offspring, often through the cytoplasm of eggs. Wolbachia can manipulate the reproductive biology of their hosts in various ways, such as feminization, parthenogenesis, male killing, and cytoplasmic incompatibility, which favor the spread and maintenance of the bacteria within host populations. The interactions between Wolbachia and their hosts have implications for insect pest management, disease transmission, and evolutionary biology.

Diethylcarbamazine (DECT or DEC) is an anti-parasitic medication used to treat infections caused by roundworms, including lymphatic filariasis (elephantiasis) and river blindness (onchocerciasis). It works by killing the parasitic worms, thus helping to prevent the progression of these diseases.

Diethylcarbamazine is typically available as a prescription oral medication in the form of tablets or capsules. The dosage and duration of treatment will depend on the type and severity of the infection being treated. It's important to note that DEC should only be taken under the supervision of a healthcare professional, as it may have side effects and potential drug interactions.

Medical Citation:
"Diethylcarbamazine." National Center for Biotechnology Information. PubChem Compound Database. U.S. National Library of Medicine. . Accessed on April 18, 2023.

Antiparasitic agents are a type of medication used to treat parasitic infections. These agents include a wide range of drugs that work to destroy, inhibit the growth of, or otherwise eliminate parasites from the body. Parasites are organisms that live on or inside a host and derive nutrients at the host's expense.

Antiparasitic agents can be divided into several categories based on the type of parasite they target. Some examples include:

* Antimalarial agents: These drugs are used to treat and prevent malaria, which is caused by a parasite that is transmitted through the bites of infected mosquitoes.
* Antiprotozoal agents: These drugs are used to treat infections caused by protozoa, which are single-celled organisms that can cause diseases such as giardiasis, amoebic dysentery, and sleeping sickness.
* Antihelminthic agents: These drugs are used to treat infections caused by helminths, which are parasitic worms that can infect various organs of the body, including the intestines, lungs, and skin. Examples include roundworms, tapeworms, and flukes.

Antiparasitic agents work in different ways to target parasites. Some disrupt the parasite's metabolism or interfere with its ability to reproduce. Others damage the parasite's membrane or exoskeleton, leading to its death. The specific mechanism of action depends on the type of antiparasitic agent and the parasite it is targeting.

It is important to note that while antiparasitic agents can be effective in treating parasitic infections, they can also have side effects and potential risks. Therefore, it is essential to consult with a healthcare provider before starting any antiparasitic medication to ensure safe and appropriate use.

Anthelmintics are a type of medication used to treat infections caused by parasitic worms, also known as helminths. These medications work by either stunting the growth of the worms, paralyzing them, or killing them outright, allowing the body to expel the worms through normal bodily functions. Anthelmintics are commonly used to treat infections caused by roundworms, tapeworms, flukeworms, and hookworms. Examples of anthelmintic drugs include albendazole, mebendazole, praziquantel, and ivermectin.

Mansonella is a genus of filarial nematodes (roundworms) that are transmitted to humans through the bites of infected blackflies or mosquitoes. There are several species within this genus, including M. perstans, M. ozzardi, and M. streptocerca, which can cause different clinical manifestations in humans.

Mansonella perstans is the most widespread species, found mainly in Africa and some parts of Central and South America. The adult worms reside in the abdominal cavity and the thoracic cavity, where they release microfilariae into the bloodstream. This species does not usually cause severe symptoms, but chronic infection can lead to general malaise, fatigue, and peripheral eosinophilia (high levels of eosinophils in the blood).

Mansonella ozzardi is found primarily in Central and South America, and its vectors are mosquitoes. The adult worms reside in the body cavities, subcutaneous tissues, and the peritoneal cavity. Infection with M. ozzardi can cause dermatological manifestations such as pruritus (itching), papular rash, and calcified nodules under the skin.

Mansonella streptocerca is transmitted through bites of infected midges in West and Central Africa. The adult worms live in the subcutaneous tissues, particularly around the head and neck regions, leading to pruritus, papular rash, and lymphadenopathy (swollen lymph nodes).

Diagnosis of Mansonella infections is typically made through the detection of microfilariae in blood samples, often obtained during nighttime due to the nocturnal periodicity of some species. Treatment usually involves the administration of antiparasitic drugs such as ivermectin or diethylcarbamazine.

Dipetalonema is a genus of parasitic nematodes (roundworms) that can infect various mammals, including humans. Two species within this genus, Dipetalonema perstans and Dipetalonema streptocerca, are known to cause human filariasis, a group of tropical diseases characterized by the presence of parasitic worms in the lymphatic system.

Dipetalonema perstans is also known as "persistent strongyloides" and can cause a condition called "tropical pulmonary eosinophilia." This species has a complex life cycle involving mosquitoes as intermediate hosts. The adult worms reside in the abdominal cavity of the human host, where they produce microfilariae that circulate in the bloodstream. When an infected mosquito takes a blood meal, it ingests the microfilariae, which then develop into infective larvae inside the mosquito. Upon subsequent bites by the mosquito, these infective larvae enter the human host and migrate to the abdominal cavity, where they mature into adults and continue the life cycle.

Dipetalonema streptocerca is primarily found in West Africa and causes a condition known as "cutaneous filariasis" or "subcutaneous filariasis." This species has a similar life cycle to D. perstans, but it involves biting midges (culicoides) instead of mosquitoes as intermediate hosts. The adult worms reside in the subcutaneous tissue, where they produce microfilariae that circulate in the skin. Infective larvae develop inside the biting midge and are transmitted to humans during blood feeding.

The symptoms of Dipetalonema infections can vary widely depending on the species and the severity of the infection. Some people may not experience any symptoms, while others may have fever, cough, wheezing, skin rashes, or lymphatic swelling (lymphedema). Treatment typically involves administration of anti-parasitic drugs such as diethylcarbamazine or ivermectin.

I'm sorry for any confusion, but "Togo" is not a medical term. It is the name of a country in West Africa, known officially as the Togolese Republic. If you have any questions about medical terminology or health-related topics, please don't hesitate to ask!

Loiasis is a tropical parasitic infection caused by the filarial nematode worm, Loa loa. It is also known as "African eye worm" due to the migration of the adult worm through the subconjunctival tissues of the eye, which is a common symptom. The infection is transmitted through the bite of deerfly or mango fly (Chrysops spp.).

After transmission, the larval form of the parasite migrates through the soft tissues and matures into an adult worm that lives in the subcutaneous tissue. Adult worms can be up to 7 cm long and may cause localized itching or a transient subconjunctival migration, which is painless but alarming to the patient.

Loiasis is usually asymptomatic, but severe symptoms such as Calabar swellings (recurrent angioedema), arthralgia, pruritus, and cardiac or respiratory complications can occur in heavy infections. Diagnosis is made by detecting microfilariae or adult worms in the blood, skin snips, or eye fluid. Treatment typically involves diethylcarbamazine citrate (DEC) therapy, but ivermectin and albendazole can also be used. Preventive measures include avoiding fly bites through the use of protective clothing, insect repellents, and bed nets.

Dirofilaria is a genus of parasitic nematode (roundworm) that can cause heartworm disease in animals such as dogs, cats, and ferrets. The most common species to infect pets is Dirofilaria immitis. These worms are transmitted through the bite of an infected mosquito. The larvae enter the host's body and migrate to the heart and pulmonary arteries, where they mature into adults and produce offspring (microfilaria). The presence of these worms can lead to serious health problems and even death in severe cases if left untreated. Regular prevention through veterinarian-prescribed medication is recommended for pets at risk of infection.

Antinematodal agents are a type of medication used to treat infections caused by nematodes, which are also known as roundworms. These agents work by either killing the parasitic worms or preventing them from reproducing. Some examples of antinematodal agents include albendazole, ivermectin, and mebendazole. These medications are used to treat a variety of nematode infections, such as ascariasis, hookworm infection, and strongyloidiasis. It is important to note that the use of antinematodal agents should be under the guidance of a healthcare professional, as they can have side effects and may interact with other medications.

I'm sorry for any confusion, but "Guatemala" is not a medical term or concept. It is the name of a country located in Central America. If you have any questions related to medical terminology or health-related topics, I would be happy to help with those!

Keratitis is a medical condition that refers to inflammation of the cornea, which is the clear, dome-shaped surface at the front of the eye. The cornea plays an essential role in focusing vision, and any damage or infection can cause significant visual impairment. Keratitis can result from various causes, including bacterial, viral, fungal, or parasitic infections, as well as trauma, allergies, or underlying medical conditions such as dry eye syndrome. Symptoms of keratitis may include redness, pain, tearing, sensitivity to light, blurred vision, and a feeling of something foreign in the eye. Treatment for keratitis depends on the underlying cause but typically includes antibiotics, antivirals, or anti-fungal medications, as well as measures to alleviate symptoms and promote healing.

Filariasis is a parasitic disease caused by infection with roundworms of the Filarioidea type. The infection is spread through the bite of infected mosquitoes and can lead to various symptoms depending on the type of filarial worm, including lymphatic dysfunction (elephantiasis), eye damage (onchocerciasis or river blindness), and tropical pulmonary eosinophilia. The disease is prevalent in tropical areas with poor sanitation and lack of access to clean water. Preventive measures include wearing protective clothing, using insect repellents, and sleeping under mosquito nets. Treatment typically involves the use of antiparasitic drugs such as diethylcarbamazine or ivermectin.

I apologize for any confusion, but "Ecuador" is not a medical term or concept. It is the name of a country located in South America, officially known as the "República del Ecuador." If you have any questions related to medicine or health, I would be happy to try and help answer those for you!

Oxytetracycline is a broad-spectrum antibiotic, which is part of the tetracycline class. It works by inhibiting bacterial protein synthesis, thereby preventing bacterial growth and reproduction. Medical definition: "A linear tetra cyclic amide antibiotic derived from Streptomyces rimosus, with a wide range of antibacterial activity against both Gram-positive and Gram-negative organisms. It is used especially in the treatment of rickettsial infections, respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases." (Source: Dorland's Illustrated Medical Dictionary)

I'm sorry for any confusion, but "Liberia" is not a medical term. It is a country in West Africa, bordering the North Atlantic Ocean, between Côte d'Ivoire and Sierra Leone. Established in 1847, it was the first African republic to proclaim its independence, and is known for its unique history of being settled by freed slaves from the United States. Is there a different term or concept you would like me to define or provide information about?

'Brugia malayi' is a species of parasitic nematode (roundworm) that can infect humans and cause the tropical disease known as lymphatic filariasis. The adult worms typically reside in the lymphatic vessels, where they can cause inflammation, obstruction, and damage to the lymphatic system.

The life cycle of 'Brugia malayi' involves several stages, including microfilariae (immature worms) that are transmitted to a human host through the bite of an infected mosquito vector. Once inside the human body, the microfilariae migrate to the lymphatic vessels and mature into adult worms over a period of several months.

The symptoms of lymphatic filariasis can range from mild to severe, depending on the extent of the infection and the individual's immune response. In some cases, the disease can lead to chronic swelling and deformity of the affected limbs or genitalia, a condition known as elephantiasis.

Preventive measures for lymphatic filariasis include avoiding mosquito bites through the use of insect repellent, long-sleeved clothing, and bed nets, as well as mass drug administration programs to eliminate the parasite from affected communities.

Insect vectors are insects that transmit disease-causing pathogens (such as viruses, bacteria, parasites) from one host to another. They do this while feeding on the host's blood or tissues. The insects themselves are not infected by the pathogen but act as mechanical carriers that pass it on during their bite. Examples of diseases spread by insect vectors include malaria (transmitted by mosquitoes), Lyme disease (transmitted by ticks), and plague (transmitted by fleas). Proper prevention measures, such as using insect repellent and reducing standing water where mosquitoes breed, can help reduce the risk of contracting these diseases.

I'm sorry for any confusion, but "Guinea" is not a medical term. It is a geographical term referring to a region on the west coast of Africa, as well as the country of Equatorial Guinea and its neighboring countries. Additionally, "Guinea" can also refer to a unit of currency in Liberia.

If you have any medical concerns or questions, I would be happy to try to help answer them for you.

I'm sorry for any confusion, but "Magnoliaceae" is not a medical term. It is a taxonomic category in botany, referring to the magnolia family of flowering plants. This family includes around 220 species of trees and shrubs, many of which are known for their large, fragrant flowers. The plants are primarily native to Asia and the Americas. If you have any questions about a medical term or concept, I'd be happy to help with that instead!

Wuchereria bancrofti is a parasitic roundworm that causes lymphatic filariasis, also known as elephantiasis. It is transmitted to humans through the bite of infected mosquitoes. The worms infect the lymphatic system and can lead to chronic swelling of body parts such as the limbs, breasts, and genitals, as well as other symptoms including fever, chills, and skin rashes. Wuchereria bancrofti is a significant public health problem in many tropical and subtropical regions around the world.

Setaria nematodes are a type of roundworm that belongs to the family Setariidae. These parasitic worms primarily infect birds, but some species can also infect mammals, including humans. The most common Setaria nematode that infects humans is Setaria digitata, which is found mainly in Asia and is transmitted through the consumption of raw or undercooked freshwater snails or fish.

In humans, Setaria nematodes typically cause mild symptoms or are asymptomatic. However, in some cases, they can lead to the development of eosinophilic meningitis, an inflammation of the membranes surrounding the brain and spinal cord, which can cause headaches, stiff neck, fever, and other neurological symptoms.

Setaria nematodes have a complex life cycle that involves several hosts, including snails, fish, and birds. Humans can become accidental hosts when they ingest infective larvae present in contaminated food or water. Once inside the human body, the larvae migrate to various tissues, such as the brain, eyes, or subcutaneous tissue, where they mature into adults and produce eggs. The eggs are then excreted from the body through feces or other bodily fluids.

Preventing Setaria nematode infections involves avoiding the consumption of raw or undercooked freshwater snails or fish and practicing good hygiene, such as washing hands thoroughly before eating or preparing food. In cases where infection occurs, treatment typically involves administering anthelmintic drugs to kill the worms and alleviate symptoms.

In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.

"Western Africa" is a geographical region that consists of several countries located in the western part of the African continent. The United Nations defines Western Africa as the 16 countries of Benin, Burkina Faso, Cape Verde, Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, and Togo.

The region is characterized by a diverse range of cultures, languages, and ethnic groups, as well as a variety of landscapes, including coastal areas, savannas, and deserts. Western Africa has a rich history, with many ancient kingdoms and empires having existed in the region, such as the Ghana Empire, Mali Empire, and Songhai Empire.

In medical contexts, "Western Africa" may be used to describe the epidemiology, distribution, or characteristics of various health conditions or diseases that are prevalent in this geographical region. For example, certain infectious diseases such as malaria, HIV/AIDS, and Ebola virus disease are more common in Western Africa than in other parts of the world. Therefore, medical researchers and practitioners may use the term "Western Africa" to refer to the specific health challenges and needs of the populations living in this region.

Chorioretinitis is a medical term that refers to the inflammation of the choroid and the retina, which are both important structures in the eye. The choroid is a layer of blood vessels that supplies oxygen and nutrients to the retina, while the retina is a light-sensitive tissue that converts light into electrical signals that are sent to the brain and interpreted as visual images.

Chorioretinitis can be caused by various infectious and non-infectious conditions, such as bacterial, viral, fungal, or parasitic infections, autoimmune diseases, or cancer. The symptoms of chorioretinitis may include decreased vision, floaters, blurry vision, sensitivity to light, and eye pain. Treatment for chorioretinitis depends on the underlying cause and may include antibiotics, antiviral medications, corticosteroids, or other immunosuppressive therapies. It is important to seek medical attention promptly if you experience any symptoms of chorioretinitis, as timely diagnosis and treatment can help prevent permanent vision loss.

'Insect control' is not a term typically used in medical definitions. However, it generally refers to the methods and practices used to manage or reduce the population of insects that can be harmful or disruptive to human health, food supply, or property. This can include various strategies such as chemical pesticides, biological control agents, habitat modification, and other integrated pest management techniques.

In medical terms, 'vector control' is a more relevant concept, which refers to the specific practices used to reduce or prevent the transmission of infectious diseases by insects and other arthropods that act as disease vectors (such as mosquitoes, ticks, and fleas). Vector control measures may include the use of insecticides, larvicides, biological control agents, environmental management, personal protection methods, and other integrated vector management strategies.

A larva is a distinct stage in the life cycle of various insects, mites, and other arthropods during which they undergo significant metamorphosis before becoming adults. In a medical context, larvae are known for their role in certain parasitic infections. Specifically, some helminth (parasitic worm) species use larval forms to infect human hosts. These invasions may lead to conditions such as cutaneous larva migrans, visceral larva migrans, or gnathostomiasis, depending on the specific parasite involved and the location of the infection within the body.

The larval stage is characterized by its markedly different morphology and behavior compared to the adult form. Larvae often have a distinct appearance, featuring unsegmented bodies, simple sense organs, and undeveloped digestive systems. They are typically adapted for a specific mode of life, such as free-living or parasitic existence, and rely on external sources of nutrition for their development.

In the context of helminth infections, larvae may be transmitted to humans through various routes, including ingestion of contaminated food or water, direct skin contact with infective stages, or transmission via an intermediate host (such as a vector). Once inside the human body, these parasitic larvae can cause tissue damage and provoke immune responses, leading to the clinical manifestations of disease.

It is essential to distinguish between the medical definition of 'larva' and its broader usage in biology and zoology. In those fields, 'larva' refers to any juvenile form that undergoes metamorphosis before reaching adulthood, regardless of whether it is parasitic or not.

... armillata Onchocerca cervicalis Onchocerca dukei Onchocerca fasciata Onchocerca flexuosa Onchocerca gibsoni ... Onchocerca gutturosa Onchocerca jakutensis Onchocerca linealis Onchocerca lupi Onchocerca ochengi Onchocerca ramachandrini ... Onchocerca is a genus of parasitic roundworm. It contains one human parasite - Onchocerca volvulus - which is responsible for ... Onchocerca tubingensis Onchocerca volvulus Wikispecies has information related to Onchocerca. "Medical Microbiology" Archived 7 ...
... is a species of nematodes belonging to the family Onchocercidae. The species is found in Australia. " ... "Onchocerca gibsoni". www.gbif.org. Retrieved 4 October 2021. v t e (Articles with short description, Short description is ...
... is a filarial (arthropod-borne) nematode (roundworm) that causes onchocerciasis (river blindness), and is ... John O'Neill, an Irish surgeon, first described Onchocerca volvulus in 1874, when he found it to be the causative agent of ' ... Greene, B.M.; Gbakima, A.A.; Albiez, E.J.; Taylor, H.R. (1985). "Humoral and cellular immune responses to Onchocerca volvulus ... "Onchocerca volvulus". NCBI Taxonomy Browser. 6282. (CS1 Dutch-language sources (nl), Articles with short description, Short ...
... is a species of nematodes belonging to the family Onchocercidae. The species is found Africa and Northern ... "Onchocerca gutturosa Neumann, 1910". www.gbif.org. Retrieved 4 October 2021. v t e (Articles with short description, Short ...
"Zoonotic Onchocerca lupi infection in a 22-month-old child in Arizona: first report in the United States and a review of the ... Onchocerca lupi is a nematode that causes ocular onchocerciasis, an eye disease, in canines and felines. The parasite was first ... The other Onchocerca spp., O. volvulus, is a human parasite that causes ocular onchocerciasis in human and affects 37 million ... "Onchocerca lupi infection in Turkey: a unique case of a rare human parasite." Acta Parasitologica 58.3 (2013): 384-388. Mowlavi ...
... is the name of a nematode. It was discovered in 1974 and published by O. Bain und H. Schulz-Key in ... The Free Dictionary H Schulz-Key, O Bain: A fourth species of Onchocerca, O. garmsi n.sp. from the European deer (author's ... The adult worms of Onchocerca tubingensis are found in subcutaneous nodules on the caudal part of the back, while the ... transl) Archived 2012-04-06 at the Wayback Machine Schulz-Key, H; Bain, O (1976). "A fourth species of Onchocerca, O. Garmsi n. ...
Robles was the first person to describe the etiology of the disease, correctly attributing it to infection with Onchocerca ... Puente Rodolfo Robles Fee, W. T. (September 1919). "The Epidemic of Filaria-Onchocerca". California State Journal of Medicine. ... Onchocerca volvulus Transmission Has Been Eliminated from the Central Endemic Zone". The American Journal of Tropical Medicine ...
Onchocerca originated in Africa and was exported to the Americas by the slave trade, as part of the Columbian exchange that ... Onchocerca ochengi, the closest relative of O. volvulus, lives in intradermal cavities in cattle, and is also spread by black ... 2010). "Lack of Onchocerca volvulus transmission in the northern focus in Chiapas". Am. J. Trop. Med. Hyg. 83 (1): 15-20. doi: ... The Onchocerca volvulus main habitat is fast flowing rivers, Onchocerciasis is more commonly found along the large rivers in ...
Onchocerca ochengi causes lymphatic filariasis in cattle. James WD, Berger T, Elston D (2015). Andrews' Diseases of the Skin: ...
... with a relatively high level of infection by the parasitic worm Onchocerca volvulus, the causative agent of river blindness. ... "The Effects of Drugs on Onchocerca volvulus: 4. Trials of Melarsonyl Potassium". World Health Organization Bulletin. 42 (1): ...
The causative agent of canine onchocerciasis is Onchocerca lupi. The disease occurs in North America and some European ... Z. Egyed et al.: Morphologic and genetic characterization of Onchocerca lupi infecting dogs. In: Veterinary Parasitology 102 ( ...
Brumpt E (1919) Une nouvelle filaire pathogène parasite de l'homme (Onchocerca caecutiens, n.sp.). Bull Soc Path Exot 12: 464- ... Filarial worm infection of an adult Onchocerca in America, 2. Erisipela de la costa, an oedema of the face, 3. Conjunctivitis ...
Yagi K, Bain O, Shoho C. "Onchocerca suzukii n. sp. and O. skrjabini (=O. tarsicola) from a relict bovid, Capricornis crispus, ...
Onchocercal keratitis, which follows Onchocerca volvulus infection by infected blackfly bite. These blackfly, Simulium, usually ...
They also transmit Onchocerca nematode worms to cattle causing bovine onchocerciasis. The former suborder Cyclorrhapha is now ...
ISBN 978-3-662-00226-1. Duke, BO (1968). "Reinfections with Onchocerca volvulus in cured patients exposed to continuing ... Premunity occurs in infections of babesiosis, malaria Onchocerca volvulus, and Trichomonas. Herd immunity Adaptive immune ...
Onchocerca Onchocerca gibsoni (parasite of cattle in Asia and Australia) Onchocerca gutturosa (parasite of cattle in Africa, ... Onchocerca lupi (parasite of canines in the United States, Greece, Portugal, Germany, Hungary, Switzerland, and Canada), cause ... Europe, and North America) Onchocerca volvulus (parasite of humans in Africa, six countries in Latin America, and Yemen), cause ... Isolation of Onchocerca lupi in dogs and black flies, California, USA. Emerg Infect Dis 2015 May 5. https://dx.doi.org/10.3201/ ...
On the anatomy and possible mode of transmission of Filaria (Onchocerca) gibsoni. (1910). Royal Society of New South Wales. The ...
The other two are Mansonella streptocerca and Onchocerca volvulus (causes river blindness). Maturing larvae and adults of the " ... and Onchocerca volvulus in rain forest villages of Cameroon". Medical Microbiology and Immunology. 192 (1): 15-21. doi:10.1007/ ...
Wuchereria and Onchocerca are directly transmitted by mosquitoes. In the developing world, the use of contaminated water is a ... Onchocerca volvulus infection) Soil-transmitted helminthiasis - this includes ascariasis (Ascaris lumbricoides infection), ...
Examination of skin snips will identify microfilariae of Onchocerca volvulus and M. streptocerca. Skin snips can be obtained ... Additionally, to differentiate the skin-dwelling filariae M. streptocerca and Onchocerca volvulus, a nested polymerase chain ... "The morphological discrimination of microfilariae of Onchocerca volvulus from Mansonella ozzardi" (PDF). Parasitology. 127 (Pt ...
... yet unlike other Black flies these species are not carriers of Onchocerca volvulus. List of Ethiopian rivers Schütt, Brigitta, ...
Onchocerca volvulus] is involved in some way, but it is a little puzzling because [the worm] is fairly common in areas that do ... "We could not establish any hint that Onchocerca volvulus is actually going into the brain, but what we cannot exclude is that ... but it is believed to be connected to infestations of the parasitic worm Onchocerca volvulus, which is prevalent in all ... "Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus". Science Translational Medicine. 9 ( ...
... a disease caused by the parasitic worm Onchocerca volvulus. In a 2017 publication in the journal Science Translational Medicine ... "Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus". Science Translational Medicine. 9 ( ...
Onchocerca volvulus manifests itself in the eyes, causing "river blindness" (onchocerciasis), one of the leading causes of ... Intradermal onchocerciasis of cattle results in losses in leather due to Onchocerca dermata, O. ochengi, and O. dukei. O. ... Subcutaneous filariasis is caused by Loa loa (the eye worm), Mansonella streptocerca, and Onchocerca volvulus. These worms ...
... the Onchocerca volvulus, Necator americanus, Wuchereria bancrofti and Dracunculus medinensis are human parasites. Some of ...
Onchocerca force their own way out of the insect's head into the pool of blood. Triatomine bugs are responsible for the ...
... double-blind study of moxidectin in Onchocerca volvulus infection". PLOS Neglected Tropical Diseases. 8 (6): e2953. doi:10.1371 ...
Irvine M, Huima T, Prince AM, Lustigman S (May 1994). "Identification and characterization of an Onchocerca volvulus cDNA clone ... and an Onchocerca volvulus antigen. Goetinck S, Waterston RH (October 1994). "The Caenorhabditis elegans muscle-affecting gene ...
The other two filarial nematodes are Loa loa (the African eye worm), and Onchocerca volvulus (river blindness). The worm is ... M. streptocerca infections fortunately do not cause any nodules, skin disease, or ocular infections like that of Onchocerca ...
Onchocerca armillata Onchocerca cervicalis Onchocerca dukei Onchocerca fasciata Onchocerca flexuosa Onchocerca gibsoni ... Onchocerca gutturosa Onchocerca jakutensis Onchocerca linealis Onchocerca lupi Onchocerca ochengi Onchocerca ramachandrini ... Onchocerca is a genus of parasitic roundworm. It contains one human parasite - Onchocerca volvulus - which is responsible for ... Onchocerca tubingensis Onchocerca volvulus Wikispecies has information related to Onchocerca. "Medical Microbiology" Archived 7 ...
A genomic comparison of 27 global isolates of Onchocerca volvulus, the agent of river blindness, elucidates its evolutionary ... Ongoing elimination efforts have altered the global distribution of Onchocerca volvulus, the agent of river blindness, and ...
... of Onchocerca volvulus from skin and eyes of onchocerciasis patients while adult filaria remains alive and reproductive, and ... Chemokines and cytokines in patients with an occult Onchocerca volvulus infection Microbes Infect. 2012 May;14(5):438-46. doi: ... Repeated ivermectin treatment will clear microfilaria (Mf) of Onchocerca volvulus from skin and eyes of onchocerciasis patients ...
This study analysed the impact and the extent by which parental Onchocerca volvulus infection, intensity of transmission of O. ... This study analysed the impact and the extent by which parental Onchocerca volvulus infection, intensity of transmission of O. ... Impact of parental onchocerciasis and intensity of transmission on development and persistence of Onchocerca volvulus infection ...
Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca ... Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca ... Onchocerca volvulus, the infectious agent of onchocerciasis. We therefore sought to determine whether antibodies produced by ...
Canine Infections with Onchocerca lupi Nematodes, United States, 2011-2014 Cite CITE. Title : Canine Infections with Onchocerca ... The Onchocerca lupi nematode infects dogs, cats, and humans, but whether it can be spread by coyotes has been unknown. We ... "Onchocerca lupi Nematodes in Dogs Exported from the United States into Canada" 22, no. 8 (2016). Verocai, Guilherme G. et al. " ... The Onchocerca lupi nematode is an emerging helminth capable of infecting pets and humans. We detected this parasite in 2 dogs ...
Onchocerca volvulus. Search for this term in our Faculty Database. View this term at the NCBI website ... Mesh term Onchocerca. Browse to parent terms:. Filarioidea. Description. A genus of parasitic nematodes whose organisms live ...
The nematode Onchocerca flexuosa is a Wolbachia-free parasite that causes onchocerciasis in deer. ... There are 2 genome projects for Onchocerca flexuosa:*PRJEB512: Wellcome Trust Sanger Institute (Strain Spain/Cordoba) ...
Onchocerca fasciata is a prevalent filarial species in camelids of Asia and Africa forming nodules in the skin of dromedary and ... Dohnal J, Blinn J, Wahl G, Schulz-Key H. Distribution of microfilariae of Onchocerca lienalis and Onchocerca gutturosa in the ... Hussein HS, Atta el Mannan AM, el Sinnary K. Onchocerca armillata Railliet and Henry, 1909 and Onchocerca gutturosa (Neumann, ... is a distinctive feature in species of the genus Onchocerca. In females of O. fasciata, the longest Onchocerca species reaching ...
Onchocerca volvulus. Like the deer fly and loa loa worm, the worm-like Onchocerca volvulus parasite is passed to a new host ...
Onchocerca ochengi Onchocerca dukei Onchocerca gutturosa Onchocerca armillata Setaria spec. Dipetalonema spec. Filarial species ... You are here: Home1 / Tübingen students in the Programme Onchocercoses Lab2 / TUCSEN-Onchocerca-ochengi-Mf-2015 ... Onchocerca hamoni (reedbok) - vector ?? Onchocerca ochengi (substrain?) (hartebeest) - vector Simulium damnosum s.l. ... As the life-expectancy of adult Onchocerca volvulus is about 10 to 15 years, it is expected that the endemicity of human ...
Motile Onchocerca volvulus Microfilariae in the Anterior Chamber of the Eye Michael E. Gyasi ...
The genus Onchocerca encompasses parasitic nematodes including Onchocerca volvulus, causative agent of river blindness in ... The genus Onchocerca encompasses parasitic nematodes including Onchocerca volvulus, causative agent of river blindness in ... Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs. Colella, Vito;Maia, Carla;Pereira, ... Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs..pdf accesso aperto ...
Other parasitic nematodes included non-Onchocerca nematodes identified as belonging to parasitic taxa.. ** Other parasitic ...
... Author: Manchang, T. ... Immune recognition of Onchocerca volvulus proteins in the human host and animal models of onchocerciasis. DSpace Repository. ...
Onchocerca volvulus. Syphilis. Trichinella spiralis. SARS-CoV-2 (COVID-19). Fungal. Histoplasma capsulatum. ...
Onchocerciasis drug discovery studies have so far been based on in vivo models using Onchocerca species which are not the ... Onchocerca volvulus afflicts some 37 million people worldwide, and is the second leading infectious cause of blindness globally ... Onchocerca ochengi: mimic, model or modulator of O. volvulus? Parasitol Today. 1992;8(10):337-9. doi:10.1016/0169-4758(92)90068 ... Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi. BMC Complement Altern ...
Parasite Antigens Are Present in Breast Milk of Women Infected with Onchocerca volvulus ...
A Reevaluation of the Tolerability and Effects of Single-Dose Ivermectin Treatment on Onchocerca volvulus Microfilariae in the ... A Reevaluation of the Tolerability and Effects of Single-Dose Ivermectin Treatment on Onchocerca volvulus Microfilariae in the ... A Reevaluation of the Tolerability and Effects of Single-Dose Ivermectin Treatment on Onchocerca volvulus Microfilariae in the ... A Reevaluation of the Tolerability and Effects of Single-Dose Ivermectin Treatment on Onchocerca volvulus Microfilariae in the ...
Project Title: ASSESSMENTS OF ONCHOCERCA VOLVULUS INFECTION IN HUMANS AND BLACKFLIES AND ONCHOCERCIASIS RESPONSE TO IVERMECTIN ... ASSESSMENTS OF ONCHOCERCA VOLVULUS INFECTION IN HUMANS AND BLACKFLIES AND ONCHOCERCIASIS RESPONSE TO IVERMECTIN AMONG VILLAGERS ... Complete Project Topic Material(s) for ASSESSMENTS OF ONCHOCERCA VOLVULUS INFECTION IN HUMANS AND BLACKFLIES AND ONCHOCERCIASIS ... NOTE: By purchasing this "ASSESSMENTS OF ONCHOCERCA VOLVULUS INFECTION IN HUMANS AND BLACKFLIES AND ONCHOCERCIASIS RESPONSE TO ...
Keywords: transmission / Onchocerca ochengi / Onchocerca volvulus / microfilariae density / Simulium damnosum s.l. Résumé:. ... Mots clé : transmission / Onchocerca ochengi / Onchocerca volvulus / densité microfilarienne / Simulium damnosum s.I. ... The intensity of natural transmission of Onchocerca ochengi and Onchocerca volvulus by anthropo-boophilic Simulium damnosum s.l ... Lintensité de la transmission naturelle de Onchocerca ochengi et Onchocerca volvulus par lanthropo-boophile Simulium damnosum ...
Dive into the research topics of Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and ... T1 - Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and its overexpression and promoter ... Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and its overexpression and promoter ... Gene structure of the extracellular glutathione S-transferase from Onchocerca volvulus and its overexpression and promoter ...
... the presence of Onchocerca flexuosa (Wedl, 1856) was discovered and investigated in 110 red deer (Cervus elaphus) shot in the ... Between 2005 and 2007, the presence of Onchocerca flexuosa (Wedl, 1856) was discovered and investigated in 110 red deer (Cervus ... Levels of Infection, Pathology and Nodule Size of Onchocerca flexuosa (Nematoda: Onchocercidae) in Red Deer (Cervus elaphus) ... Pathology and Nodule Size of Onchocerca flexuosa (Nematoda: Onchocercidae) in Red Deer (Cervus elaphus) from Northern Spain" ( ...
Aqueous Humor and Serum IgE Antibody in Experimental Ocular Onchocerca Infection of Guinea Pigs ... in Experimental Ocular Onchocerca Infection of Guinea Pigs in another window ... in Experimental Ocular Onchocerca Infection of Guinea Pigs ...
Onchocerca larval migration. Laryngeal paralysis. Facial pruritis incorporated with skin allergies (urticaria) ...
... and Onchocerca ochengi (Howe et al., 2017)) were included to distinguish GI-nematode specific proteins. Genomes for relevant ...
Ocular zoonotic onchocerca infection in a resident of Oregon. Am J Trop Med Hyg. 2012 Dec. 87(6):1073-5. [QxMD MEDLINE Link]. [ ... Zoonotic Onchocerca lupi infection in a 22-month-old child in Arizona: first report in the United States and a review of the ... Effects of standard and high doses of ivermectin on adult worms of Onchocerca volvulus: a randomised controlled trial. Lancet. ... Moxidectin, a macrocyclic lactone, is an anthelmintic indicated for the treatment of onchocerciasis due to Onchocerca volvulus ...
Onchocerca ochengi: A0A182EJC5; Litomosoides sigmodontis: A0A3P6U6X0; Brugia timori: A0A0R3Q8V2; Phocoena sinus: A0A8C9B3Q4; ... Onchocerca volvulus: A0A044TMQ9; Brugia pahangi: A0A0N4TLS2; Brugia malayi: A0A4E9FFK1, A0A0K0JD75; Acanthocheilonema viteae: ... Onchocerca flexuosa: A0A238BX73; Alligator sinensis: A0A1U7RE43; Phascolarctos cinereus: A0A6P5LL69; Orthonyx spaldingii: ...
Categories: Onchocerca Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 22 ...
  • Onchocerciasis is a dermatitis in equines and ruminants caused by microfilariae produced by adult Onchocerca . (merckvetmanual.com)
  • The survey result revealed that none of the study participants regardless of age, sex, and location demonstrated skin snip Onchocerca microfilariae. (hindawi.com)
  • Female Onchocerca volvulus worms produce thousands of microfilariae which exit the nodules, move into the dermis, and enter the eye causing cutaneous and eye disease [ 1 , 2 ]. (hindawi.com)
  • Cell/antibody interactions in vitro against microfilariae of Onchocerca gibsoni / by Syamsul Bahri Siregar. (who.int)
  • The genus Onchocerca encompasses parasitic nematodes including Onchocerca volvulus, causative agent of river blindness in humans, and the zoonotic Onchocerca lupi infecting dogs and cats. (uniba.it)
  • The sequence of this 46-kD Ro/SS-A protein (calreticulin) has significant homology to lambda Ral-1, a recombinant cDNA clone corresponding to a major antigen of the nematode, Onchocerca volvulus, the infectious agent of onchocerciasis. (jci.org)
  • The nematode Onchocerca flexuosa is a Wolbachia-free parasite that causes onchocerciasis in deer. (wormbase.org)
  • Onchocerciasis, caused by the parasitic nematode, Onchocerca volvulus afflicts some 37 million people worldwide, and is the second leading infectious cause of blindness globally. (biomedcentral.com)
  • Onchocerciasis is a neglected tropical disease caused by the filarial nematode, Onchocerca volvulus . (biomedcentral.com)
  • Two highly similar genes encoding unique extracellular, glycosylated glutathione S-transferases (GSTs) of the human-pathogenic nematode, Onchocerca volvulus (Ov-GST1a and Ov-GST1b), have been isolated and characterised. (aber.ac.uk)
  • Onchocerciasis (river blindness) is a neglected tropical parasitic disease (NTD) caused by a filarial nematode worm called Onchocerca volvulus encapsulated in nodules under the skin. (hindawi.com)
  • It contains one human parasite - Onchocerca volvulus - which is responsible for the neglected disease Onchocerciasis, also known as "river blindness" because the infected humans tend to live near rivers where host black flies live. (wikipedia.org)
  • Repeated ivermectin treatment will clear microfilaria (Mf) of Onchocerca volvulus from skin and eyes of onchocerciasis patients while adult filaria remains alive and reproductive, and such occult O. volvulus infection may persist for years. (nih.gov)
  • Onchocerciasis drug discovery studies have so far been based on in vivo models using Onchocerca species which are not the closest to O. volvulus, and which may therefore, not adequately mimic the natural infection in humans. (biomedcentral.com)
  • NOTE: By purchasing this "ASSESSMENTS OF ONCHOCERCA VOLVULUS INFECTION IN HUMANS AND BLACKFLIES AND ONCHOCERCIASIS RESPONSE TO IVERMECTIN AMONG VILLAGERS AROUND GURARA DAM, KADUNA STATE, NIGERIA" CodeMint project, it means you have read and agreed to our Terms of Use and our Privacy Policy . (codemint.net)
  • Moxidectin, a macrocyclic lactone, is an anthelmintic indicated for the treatment of onchocerciasis due to Onchocerca volvulus in patients aged 12 years and older. (medscape.com)
  • Onchocerciasis, commonly known as river blindness, is a neglected tropical disease (NTD) caused by the parasitic worm Onchocerca volvulus . (nri.org)
  • Although the Onchocerciasis Control Programme (OCP) in West Africa (1975-2002) has greatly improved the situation in its 11 participating countries, infection by Onchocerca volvulus (the causal agent of River Blindness ) still poses an important public health problem in many areas of Africa, Yemen, and Latin America. (imperial.ac.uk)
  • Onchocerciasis or "river blindness" is caused by the parasitic worm Onchocerca volvulus. (who.int)
  • Onchocerciasis - or "river blindness" - is a parasitic disease caused by the filarial worm Onchocerca volvulus transmitted by repeated bites of infected blackflies (Simulium spp. (who.int)
  • Onchocerca armillata Onchocerca cervicalis Onchocerca dukei Onchocerca fasciata Onchocerca flexuosa Onchocerca gibsoni Onchocerca gutturosa Onchocerca jakutensis Onchocerca linealis Onchocerca lupi Onchocerca ochengi Onchocerca ramachandrini Onchocerca tubingensis Onchocerca volvulus Wikispecies has information related to Onchocerca. (wikipedia.org)
  • Onchocerca lupi infectionisreportedprimarilyinsymp- by comparing them with sequences available in GenBank. (cdc.gov)
  • Gilleard, J. S. 2016, Onchocerca lupi Nematodes in Dogs Exported from the United States into Canada. (cornell.edu)
  • This study analysed the impact and the extent by which parental Onchocerca volvulus infection, intensity of transmission of O. volvulus infective 3rd-stage larvae (L3) and anthropometric factors may influence the acquisition, development and persistence of O. volvulus infection in offspring. (nih.gov)
  • Levels of Infection, Pathology and Nodule Size of Onchocerca flexuosa " by Ramon A. Carreno, María del Rosario Hidalgo-Argüello et al. (owu.edu)
  • Moreover there seems to be an association between epilepsy and the degree of infection with Onchocerca volvulus. (kit.nl)
  • The intensity of natural transmission of Onchocerca ochengi and Onchocerca volvulus by anthropo-boophilic Simulium damnosum s.l. was studied longitudinally in two cattle watering sites of a cattle ranch within a predominantly cattle populated area of the Guinea savanna of Cameroon and related to cattle O. ochengi skin microfilaria abundance. (vetres.org)
  • Dynamique de la transmission de Onchocerca ochengi et corrélation entre la densité de leurs microfilaires chez les bovins et le potentiel de transmission. (vetres.org)
  • L'intensité de la transmission naturelle de Onchocerca ochengi et Onchocerca volvulus par l'anthropo-boophile Simulium damnosum s.I. a été étudiée longitudinalement à deux points d'eau d'un élevage de bovins, situé dans une région de savane guinéenne du Cameroun comportant une population principalement bovine, et a été corrélée à l'abondance en microfilaires de O. ochengi dans la peau des bovins. (vetres.org)
  • Le captage des microfilaires de O. ochengi par les mouches vecteurs était dépendant de la densité en microfilaires dans le derme de l'hôte. (vetres.org)
  • Le PTM de O. ochengi était positivement corrélé à la densité en microfilaires du derme. (vetres.org)
  • Between 2005 and 2007, the presence of Onchocerca flexuosa (Wedl, 1856) was discovered and investigated in 110 red deer (Cervus elaphus) shot in the Riaño Regional Hunting Reserve, in the province of León (north-western Spain). (owu.edu)
  • Onchocerca fasciata is a prevalent filarial species in camelids of Asia and Africa forming nodules in the skin of dromedary and Bactrian camels. (biomedcentral.com)
  • Zoonotic onchocercosis has been attributed to species aries of Amaxades (25°0427E, 41°0712N, altitude 56 that primarily infest cattle ( Onchocerca gutturosa ), m), a small village of 1,000 inhabitants between Xanthi horses ( O. cervicalis ), the European deer ( O. jakutensis ), and Komotini, on the border between Greece and Turkey. (cdc.gov)
  • The worm (Onchocerca volvulus) is transmitted to humans as immature larvae through bites of infected black flies. (medindia.net)
  • The most consistent finding in cases is a higher incidence of exposure to a parasite called Onchocerca volvulus than in community controls of the same ages. (cdc.gov)
  • This study has provided new data on the kinetics of Mf in the skin and eyes after IVM treatment of persons with light to moderate intensity Onchocerca volvulus infections that are common in Africa at this time. (wustl.edu)
  • Thus, diagnosis of Onchocerca -associated dermatitis may be based on responsiveness to microfilaricidal treatment. (merckvetmanual.com)
  • The taxonomic status of the three species of Onchocerca currently recognized in the USA, and other previously recognized species, is under debate. (merckvetmanual.com)
  • The WHO estimates that at least 12-15 years of annual treatment are required in high and moderate endemic areas to eliminate transmission, corresponding to the lifespan of the adult Onchocerca volvulus . (nri.org)
  • Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca volvulus. (jci.org)
  • It contains one human parasite - Onchocerca volvulus - which is responsible for the neglected disease Onchocerciasis, also known as "river blindness" because the infected humans tend to live near rivers where host black flies live. (wikipedia.org)
  • Onchocerca volvulus is a parasitic worm that causes river blindness, transmitted by blackflies and characterized by nodules under the skin, itching, and potential loss of vision. (hbot-india.com)
  • Human onchocerciasis (river blindness) caused by Onchocerca volvulus is endemic in 30 countries of sub-Saharan Africa and Yemen. (biomedcentral.com)
  • Many studies have reported an association between Nodding syndrome and Onchocerca volvulus , a parasitic worm that can also cause river blindness. (nih.gov)
  • These flies transmit Onchocerca volvulus , the tiny parasitic worm responsible for river blindness. (nih.gov)
  • Onchocerciasis, or river blindness , is a filarial infection caused by the parasitic nematode, Onchocerca volvulus , carried by black flies of the genus Simulium . (encyclopedia.com)
  • Onchocerciasis, commonly known as "river blindness", is caused by the parasitic worm Onchocerca volvulus . (who.int)
  • Onchocerciasis - or "river blindness" - is a parasitic disease caused by the filarial worm Onchocerca volvulus transmitted by repeated bites of infected blackflies ( Simulium spp. (who.int)
  • Multivalent vaccines are being developed against Onchocerca volvulus, the causative agent of river blindness, and against Stongyloides stercoralis. (jefferson.edu)
  • Onchocerciasis, or river blindness, is caused by infection by the filarial worm Onchocerca volvulus which is transmitted by female black flies of the genus Simulium . (biomedcentral.com)
  • Organisms/diseases covered include Plasmodium (malaria), Dracunculus (Guinea worm), Onchocerca (river blindness), Wuchereria (lymphatic filarisis), and poliovirus (polio), and touch on measles and smallpox as examples of possible recurrence. (teambasedlearning.org)
  • There were hints that the syndrome might be caused by a parasitic worm called Onchocerca volvulus , which is transmitted through the bites of blackflies. (nih.gov)
  • We enrolled participants (aged ≥12 years) with at least 10 Onchocerca volvulus microfilariae per mg skin who were not co-infected with Loa loa or lymphatic filariasis microfilaraemic. (qxmd.com)
  • An experimental model of human onchocercal keratitis was produced by injecting guinea pigs subconjunctivally with microfilariae (Mf) of Onchocerca lienalis . (jamanetwork.com)
  • Dermatitis caused by neck threadworm microfilariae, Onchocerca sp. (nih.gov)
  • The N-terminal region of the cathepsin D-like aspartic protease from the human filarial parasite Onchocerca volvulus was expressed as His-tag fusion protein. (edu.au)
  • The parasite Onchocerca volvulus is well-known in its endemic areas in South and Central America and West Africa. (ima.org.il)
  • This examined 38 matched cases and controls and examined dietary as well as infectious disease factors, looking at issues such as vitamin deficiencies, a history of hunger, and current infection with the parasite Onchocerca volvulus . (scienceblogs.com)
  • Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial. (qxmd.com)
  • Hyperbaric oxygen therapy may potentially alleviate symptoms of Onchocerca volvulus infection by enhancing the immune response, promoting wound healing, and inhibiting bacterial growth in affected tissues. (hbot-india.com)
  • Zoonotic onchocercosis has been attributed to species aries of Amaxades (25°0427E, 41°0712N, altitude 56 that primarily infest cattle ( Onchocerca gutturosa ), m), a small village of 1,000 inhabitants between Xanthi horses ( O. cervicalis ), the European deer ( O. jakutensis ), and Komotini, on the border between Greece and Turkey. (cdc.gov)
  • Only 3 previous reports exist of human infection of the eye caused by zoonotic Onchocerca, 2 involving the subconjunctiva and 1 the cornea. (nih.gov)
  • Zoonotic Onchocerca (Nematoda:Filarioidea) in the cornea of a Colorado resident. (nih.gov)
  • Subconjunctival zoonotic Onchocerca in an Albanian man. (nih.gov)
  • Persons between 3 and 100 years of age diagnosed with or suspected of infection with Wuchereria bancrofti, Bugia malayi, Onchocerca volvulus, Loa loa, or other parasitic worms may be eligible for this study. (nih.gov)
  • The principle was that, by controlling breeding sites of the flies for long enough, transmission could be interrupted while waiting for the adult parasites of Onchocerca volvulus to die (in infected individuals). (cehjournal.org)
  • Onchocerca jakutensis ocular infection in Poland: a new vector-borne human health risk? (nih.gov)
  • IgG from Onchocerca -infected humans and cattle showed similar cross-reaction with both respective galectins. (biomedcentral.com)
  • Molecular approaches to the population biology of Onchocerca ocheng i in cattle (Prof. R. Post, British Mus. (uni-tuebingen.de)
  • Besides triggering allergic itching, Culicoides transmit Onchocerca larvae which move across the horse's skin, triggering crusting and itching. (eclipsemagazine.co.uk)
  • Infection by Onchocerca volvulus may be an underlying risk factor for the high burden and based upon epidemiological associations, has been proposed to cause a group of disorders-Onchocerca associated epilepsies (OAE) like nodding syndrome (NS). (ox.ac.uk)
  • To improve our understanding of the disease spectrum, we described the clinical, electroencephalographic (EEG) and magnetic resonance imaging (MRI) features of children with epilepsy and sero-positive for Onchocerca volvulus (possible OAEs other than nodding syndrome). (ox.ac.uk)
  • Overall, current infection with Onchocerca volvulus diagnosed by skin snip was more prevalent among the 38 case-patients (76.3%) than the controls (47.4%) (matched odds ratio [mOR] = 3.2). (cdc.gov)
  • Epilepsy in Onchocerca volvulus Sero-Positive Patients From Northern Uganda-Clinical, EEG and Brain Imaging Features. (ox.ac.uk)
  • Moreover there seems to be an association between epilepsy and the degree of infection with Onchocerca volvulus. (kit.nl)
  • According to the researchers, the immune system creates antibodies to fight off the parasite following infection with Onchocerca volvulus . (nih.gov)
  • To enhance the immune response for our vaccine design, truncated (residues 10-153) Onchocerca volvulus activation-associated secreted protein-1 (Ov-ASP-1) has been utilized as an adjuvant at N terminal of both the MEVs. (biorxiv.org)
  • The effects of drugs on onchocerca volvulus: II. (who.int)
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