A five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener.
Exclusive legal rights or privileges applied to inventions, plants, etc.
Hydrocarbon-rich byproducts from the non-fossilized BIOMASS that are combusted to generate energy as opposed to fossilized hydrocarbon deposits (FOSSIL FUELS).
The relative amounts of various components in the body, such as percentage of body fat.
Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)
Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
A condition in which the FORAMEN OVALE in the ATRIAL SEPTUM fails to close shortly after birth. This results in abnormal communications between the two upper chambers of the heart. An isolated patent ovale foramen without other structural heart defects is usually of no hemodynamic significance.
Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.
Antisera from immunized animals that is purified and used as a passive immunizing agent against specific BACTERIAL TOXINS.
A genus of gram-positive, facultatively anaerobic, coccoid bacteria. Its organisms occur singly, in pairs, and in tetrads and characteristically divide in more than one plane to form irregular clusters. Natural populations of Staphylococcus are found on the skin and mucous membranes of warm-blooded animals. Some species are opportunistic pathogens of humans and animals.
Infections with bacteria of the genus STAPHYLOCOCCUS.
An antitoxin used for the treatment of TETANUS.
The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.
Services providing pharmaceutic and therapeutic drug information and consultation.
Lipid-laden macrophages originating from monocytes or from smooth muscle cells.
The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Accumulations of microflora that lead to pathological plaque and calculus which cause PERIODONTAL DISEASES. It can be considered a type of BIOFILMS. It is subtly distinguished from the protective DENTAL PELLICLE.
Material applied to the tissue side of a denture to provide a soft lining to the parts of a denture coming in contact with soft tissue. It cushions contact of the denture with the tissues.
Methods of preparing tissue specimens for visualization using an electron microscope, usually a scanning electron microscope. The methods involve the creation of exact copies of the specimens by making a mold or cast (i.e., replica) of the specimen.
It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant & Hackh's Chemical Dictionary, 5th ed)
A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is a non-steroidal anti-inflammatory agent used for analgesia for postoperative pain and inhibits cyclooxygenase activity.
An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)
A non-steroidal anti-inflammatory agent (ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL) similar in mode of action to INDOMETHACIN.
A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.
An anti-inflammatory agent used in the treatment of rheumatoid arthritis. It also has uricosuric properties and has been used to treat gout.
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
A myelin protein found in the periaxonal membrane of both the central and peripheral nervous systems myelin sheaths. It binds to cells surface receptors found on AXONS and may regulate cellular interactions between MYELIN and AXONS.
An abundant cytosolic protein that plays a critical role in the structure of multilamellar myelin. Myelin basic protein binds to the cytosolic sides of myelin cell membranes and causes a tight adhesion between opposing cell membranes.
MYELIN-specific proteins that play a structural or regulatory role in the genesis and maintenance of the lamellar MYELIN SHEATH structure.
A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.
The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
Nucleoside-2',3'-cyclic phosphate nucleotidohydrolase. Enzymes that catalyze the hydrolysis of the 2'- or 3'- phosphate bonds of 2',3'-cyclic nucleotides. Also hydrolyzes nucleoside monophosphates. Includes EC 3.1.4.16 and EC 3.1.4.37. EC 3.1.4.-.
Apparatus, devices, or supplies intended for one-time or temporary use.
Further or repeated use of equipment, instruments, devices, or materials. It includes additional use regardless of the original intent of the producer as to disposability or durability. It does not include the repeated use of fluids or solutions.
Endoscopes for examining the interior of the larynx.
Application of a cauterant to the skin for the purpose of causing a superficial destruction of the epidermis and upper layers of the dermis. After healing, the treated area has new epithelium.
Techniques using energy such as radio frequency, infrared light, laser light, visible light, or acoustic energy to transfer information without the use of wires, over both short and long distances.
The amount of force generated by MUSCLE CONTRACTION. Muscle strength can be measured during isometric, isotonic, or isokinetic contraction, either manually or using a device such as a MUSCLE STRENGTH DYNAMOMETER.
A plant genus of the family RUTACEAE. They bear the familiar citrus fruits including oranges, grapefruit, lemons, and limes. There are many hybrids which makes the nomenclature confusing.

Mammalian staufen is a double-stranded-RNA- and tubulin-binding protein which localizes to the rough endoplasmic reticulum. (1/1530)

Staufen (Stau) is a double-stranded RNA (dsRNA)-binding protein involved in mRNA transport and localization in Drosophila. To understand the molecular mechanisms of mRNA transport in mammals, we cloned human (hStau) and mouse (mStau) staufen cDNAs. In humans, four transcripts arise by differential splicing of the Stau gene and code for two proteins with different N-terminal extremities. In vitro, hStau and mStau bind dsRNA via each of two full-length dsRNA-binding domains and tubulin via a region similar to the microtubule-binding domain of MAP-1B, suggesting that Stau cross-links cytoskeletal and RNA components. Immunofluorescent double labeling of transfected mammalian cells revealed that Stau is localized to the rough endoplasmic reticulum (RER), implicating this RNA-binding protein in mRNA targeting to the RER, perhaps via a multistep process involving microtubules. These results are the first demonstration of the association of an RNA-binding protein in addition to ribosomal proteins, with the RER, implicating this class of proteins in the transport of RNA to its site of translation.  (+info)

The Npc1 mutation causes an altered expression of caveolin-1, annexin II and protein kinases and phosphorylation of caveolin-1 and annexin II in murine livers. (2/1530)

We have previously demonstrated (1) an increased expression of caveolin-1 in murine heterozygous and homozygous Niemann-Pick type C (NPC) livers, and (2) an increased concentration of unesterified cholesterol in a detergent insoluble caveolae-enriched fraction from homozygous livers. To define further the relationship between caveolin-1 function and the cholesterol trafficking defect in NPC, we examined the expression and distribution of additional caveolar and signal transduction proteins. The expression of annexin II was significantly increased in homozygous liver homogenates and the Triton X-100 insoluble floating fraction (TIFF). Phosphoamino acid analysis of caveolin-1 and annexin II from the homozygous TIFF demonstrated an increase in serine and tyrosine phosphorylation, respectively. To determine the basis for increased phosphorylation of these proteins, the expression and distribution of several protein kinases was examined. The expression of PKCalpha, PKCzeta and pp60-src (protein kinases) were significantly increased in both heterozygous and homozygous liver homogenates, while PKCdelta was increased only in homozygous livers. Of the protein kinases analyzed, only CK IIalpha was significantly enriched in the heterozygous TIFF. Finally, the concentration of diacylglycerol in the homozygous TIFF was significantly increased and this elevation may modulate PKC distribution and function. These results provide additional evidence for involvement of a caveolin-1 containing cellular fraction in the pathophysiology of NPC and also suggest that the Npc1 gene product may directly or indirectly, regulate the expression and distribution of signaling molecules.  (+info)

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin. (3/1530)

The assembly and budding of human immunodeficiency virus type 1, encoded solely in the Gag protein precursor Pr55Gag, occur at the plasma membrane of infected cells. However, little is known about the routing of the Gag molecule from its site of synthesis in the cytoplasm to the site of budding, with past studies suggesting that the cytoskeleton, particularly actin, may be involved in the translocation. We have constructed a T7 promoter-driven gag gene fusion with green fluorescent protein (GFP) that expresses Gag-GFP in both cells and supernatant. The distribution of Gag-GFP was the same as Gag only, suggesting that cellular routing was not affected by fusion to GFP, and using colabelling techniques, Gag-GFP was shown to have no particular colocalisation with actin. After detergent extraction of expressing cells, Gag and Gag-GFP remained cell associated, whereas GFP only was wholly released. These data suggest that Gag may associate with other cytoskeletal components or, perhaps more likely, that a partial assembly to a large-molecular-weight intermediate occurs before localisation at the plasma membrane.  (+info)

Contrasting effects of a nonionic surfactant on the biotransformation of polycyclic aromatic hydrocarbons to cis-dihydrodiols by soil bacteria. (4/1530)

The biotransformation of the polycyclic aromatic hydrocarbons (PAHs) naphthalene and phenanthrene was investigated by using two dioxygenase-expressing bacteria, Pseudomonas sp. strain 9816/11 and Sphingomonas yanoikuyae B8/36, under conditions which facilitate mass-transfer limited substrate oxidation. Both of these strains are mutants that accumulate cis-dihydrodiol metabolites under the reaction conditions used. The effects of the nonpolar solvent 2,2,4, 4,6,8,8-heptamethylnonane (HMN) and the nonionic surfactant Triton X-100 on the rate of accumulation of these metabolites were determined. HMN increased the rate of accumulation of metabolites for both microorganisms, with both substrates. The enhancement effect was most noticeable with phenanthrene, which has a lower aqueous solubility than naphthalene. Triton X-100 increased the rate of oxidation of the PAHs with strain 9816/11 with the effect being most noticeable when phenanthrene was used as a substrate. However, the surfactant inhibited the biotransformation of both naphthalene and phenanthrene with strain B8/36 under the same conditions. The observation that a nonionic surfactant could have such contrasting effects on PAH oxidation by different bacteria, which are known to be important for the degradation of these compounds in the environment, may explain why previous research on the application of the surfactants to PAH bioremediation has yielded inconclusive results. The surfactant inhibited growth of the wild-type strain S. yanoikuyae B1 on aromatic compounds but did not inhibit B8/36 dioxygenase enzyme activity in vitro.  (+info)

Lipid exchange between mixed micelles of phospholipid and triton X-100. (5/1530)

If phospholipase catalyzed hydrolysis of phospholipid dissolved in a detergent mixed micelle is limited to the phospholipid carried by a single micelle, then hydrolysis ceases upon exhaustion of that pool. However, if the rate of phospholipid exchange between micelles exceeds the catalytic rate then all of the phospholipid is available for hydrolysis. To determine phospholipid availability we studied the exchange of 1,2-dioleoyl-sn-glycero-3-phosphocholine between mixed micelles of phospholipid and non-ionic Triton detergents by both stopped-flow fluorescence-recovery and nuclear magnetic resonance-relaxation techniques. Stopped-flow analysis was performed by combining mixed micelles of Triton and phospholipid with mixed micelles that contained the fluorescent phospholipid 1-palmitoyl-2-(12-[{7-nitro-2-1, 3-benzoxadiazo-4-yl}amino]dodecanoyl)-sn-glycero-3-phosphocholine (P-2-NBD-PC). The concentration dependence of fluorescence recovery suggested a second-order exchange mechanism that was saturable. The true second-order rate constant depends on the specific mechanism for exchange, which was not determined in this study, but the rate constant will be on the order of 106 to 107 M-1s-1. Incorporation of 1-palmitoyl-2-(16-doxylstearoyl)phosphatidylcholine into micelles increased the rate of proton relaxation and gave a limiting relaxation time of 1.3 ms. The results demonstrate that phospholipid exchange was rapid and that the phospholipid content of a single micelle did not limit the rate of phospholipid hydrolysis by phospholipases.  (+info)

Opposite behavior of two isozymes when refolding in the presence of non-ionic detergents. (6/1530)

GroEL has a greater affinity for the mitochondrial isozyme (mAAT) of aspartate aminotransferase than for its cytosolic counterpart (cAAT) (Mattingly JR Jr, Iriarte A, Martinez-Carrion M, 1995, J Biol Chem 270:1138-1148), two proteins that share a high degree of sequence similarity and an almost identical spatial structure. The effect of detergents on the refolding of these large, dimeric isozymes parallels this difference in behavior. The presence of non-ionic detergents such as Triton X-100 or lubrol at concentrations above their critical micelle concentration (CMC) interferes with reactivation of mAAT unfolded in guanidinium chloride but increases the yield of cAAT refolding at low temperatures. The inhibitory effect of detergents on the reactivation of mAAT decreases progressively as the addition of detergents is delayed after starting the refolding reaction. The rate of disappearance of the species with affinity for binding detergents coincides with the slowest of the two rate-limiting steps detected in the refolding pathway of mAAT. Limited proteolysis studies indicate that the overall structure of the detergent-bound mAAT resembles that of the protein in a complex with GroEL. The mAAT folding intermediates trapped in the presence of detergents can resume reactivation either upon dilution of the detergent below its CMC or by adding beta-cyclodextrin. Thus, isolation of otherwise transient productive folding intermediates for further characterization is possible through the use of detergents.  (+info)

PhoP-PhoQ-regulated loci are required for enhanced bile resistance in Salmonella spp. (7/1530)

As enteric pathogens, Salmonella spp. are resistant to the actions of bile. Salmonella typhimurium and Salmonella typhi strains were examined to better define the bile resistance phenotype. The MICs of bile for wild-type S. typhimurium and S. typhi were 18 and 12%, respectively, and pretreatment of log-phase S. typhimurium with 15% bile dramatically increased bile resistance. Mutant strains of S. typhimurium and S. typhi lacking the virulence regulator PhoP-PhoQ were killed at significantly lower bile concentrations than wild-type strains, while strains with constitutively active PhoP were able to survive prolonged incubation with bile at concentrations of >60%. PhoP-PhoQ was shown to mediate resistance specifically to the bile components deoxycholate and conjugated forms of chenodeoxycholate, and the protective effect was not generalized to other membrane-active agents. Growth of both S. typhimurium and S. typhi in bile and in deoxycholate resulted in the induction or repression of a number of proteins, many of which appeared identical to PhoP-PhoQ-activated or -repressed products. The PhoP-PhoQ regulon was not induced by bile, nor did any of the 21 PhoP-activated or -repressed genes tested play a role in bile resistance. However, of the PhoP-activated or -repressed genes tested, two (prgC and prgH) were transcriptionally repressed by bile in the medium independent of PhoP-PhoQ. These data suggest that salmonellae can sense and respond to bile to increase resistance and that this response likely includes proteins that are members of the PhoP regulon. These bile- and PhoP-PhoQ-regulated products may play an important role in the survival of Salmonella spp. in the intestine or gallbladder.  (+info)

Hydrodynamic properties of human erythrocyte band 3 solubilized in reduced Triton X-100. (8/1530)

The oligomeric state and function of band 3, purified by sulfhydryl affinity chromatography in reduced Triton X-100, was investigated. Size exclusion high-performance liquid chromatography showed that a homogeneous population of band 3 dimers could be purified from whole erythrocyte membranes. The elution profile of band 3 purified from membranes that had been stripped of its cytoskeleton before solubilization was a broad single peak describing a heterogeneous population of oligomers with a mean Stokes radius of 100 A. Sedimentation velocity ultracentrifugation analysis confirmed particle heterogeneity and further showed monomer/dimer/tetramer equilibrium self-association. Whether the conversion of dimer to the form described by a Stokes radius of 100 A was initiated by removal of cytoskeletal components, alkali-induced changes in band 3 conformation, or alkali-induced loss of copurifying ligands remains unclear. After incubation at 20 degrees C for 24 h, both preparations of band 3 converted to a common form characterized by a mean Stokes radius of 114 A. This form of the protein, examined by equilibrium sedimentation ultracentrifugation, is able to self-associate reversibly, and the self-association can be described by a dimer/tetramer/hexamer model, although the presence of higher oligomers cannot be discounted. The ability of the different forms of the protein to bind stilbene disulfonates revealed that the dimer had the highest inhibitor binding affinity, and the form characterized by a mean Stokes radius of 114 A to have the lowest.  (+info)

CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): ABSTRACT MtrA is a member of the AraC family of transcriptional regulators and has been shown to play an important role in enhancing transcription of themtrCDE operon, which encodes a tripartite multidrug efflux pump, when gonococci are exposed to a sublethal level of antimicrobials. Heretofore, the DNA-binding properties of MtrA were unknown. In order to understand howMtrA activatesmtrCDE expression, we successfully purifiedMtrA and found that it could bind specifically to themtrCDE promoter region. The affinity of MtrA for themtrCDE promoter increased 2-fold in the presence of a known effector and sub-strate of the MtrCDE pump, the nonionic detergent Triton X-100 (TX-100). When placed in competition withMtrR, the tran-scriptional repressor ofmtrCDE, MtrA was found to bind with apparent lower affinity thanMtrR to the same region. However, preincubation of MtrA with TX-100 prior to addition of the promoter-containing DNA probe
2440 We previously reported that EGCG inhibits growth and activation of the EGF receptor (EGFR) and downstream signaling pathways in human colon cancer cells (Shimizu et al., Clin. Cancer Res. 11, 2735-2746, 2005), but the precise mechanism is not known. Several proteins, including EGFR, are believed to partition into detergent-insoluble liquid ordered membrane domains enriched in cholesterol, sphingomyelin, and gangliosides, so-called lipid rafts. Therefore, we examined the effects of EGCG on ordered membrane domains in HT29 colon cancer cells. When the cells were first treated with the fluorescent lipid analog DiIC16,, which preferentially incorporates into ordered domains in the plasma membrane, subsequent treatment with EGCG caused a marked increase the sensitivity of the plasma membrane to extraction by cold Triton X-100, indicating that liquid ordered domains are decreased. Pretreatment with EGCG also inhibited subsequent incorporation of DiIC16 into the plasma membrane, indicating that ...
HI there! I have been trying to get protein extract from embryos for immunoprecipitaton. I have tried some of the published protocol, such as embryo extract buffer, PBS with triton-X. Then, homogenized embryos with a pestle. I have not been able to get WHOLE EMBRYOS LYSATE! I need HELP!! If you have a protocol or any SUGGESTIONS. PLEASE HELP! THANKS! Min ...
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Prolonged Gi/o protein-coupled receptor activation has been shown to lead to receptor internalization and receptor desensitization. In addition, it is well established that although acute activation of these receptors leads to inhibition of adenylyl cyclase (AC), long-term activation results in increased AC activity (especially evident on removal of the inhibitory agonist), a phenomenon defined as AC superactivation or sensitization. Herein, we show that chronic exposure to agonists of Gi-coupled receptors also leads to a decrease in cholate detergent solubility of G protein subunits, and that antagonist treatment after such chronic agonist exposure leads to a time-dependent reversal of the cholate insolubility. With Chinese hamster ovary and COS cells transfected with several Gi/o-coupled receptors (i.e., μ- and κ-opioid, and m4-muscarinic), we observed that although no overall change occurred in total content of Gαi- and β1-subunits, chronic agonist treatment led to a marked reduction in ...
Journal article published in Food Research International. Abstract: Recently the use of ozone as sanitizing agent has been proposed on winegrapes in order to
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Description of disease Detergent poisoning. Treatment Detergent poisoning. Symptoms and causes Detergent poisoning Prophylaxis Detergent poisoning
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摘要: 研究了剩余活性污泥中复合水解酶的提取分离及制成洗涤用复合水解酶制剂的方法. 离心脱水的污泥按料液比1∶2加入1%的Triton X-100水溶液搅拌提取60 min,蛋白酶的提取率为71.7%;酶提取液经膜分离和浓缩后用70%乙醇沉淀,沉淀经冷冻干燥得复合水解酶粉末,每千克剩余活性污泥可制备1.7 g复合水解酶粉,其中胶原蛋白酶、碱性蛋白酶、脂肪酶、淀粉酶、纤维素酶的酶活分别为4.216、3.714、11.915、3.060和1.291 U/mg;在复合水解酶液中加入由4%蔗糖、4%甘露醇、30 mmol/L甘氨酸和10 mmol/L MgSO4组成的复合稳定剂可大大延长酶的保存期;再按固体物比4%复合酶粉末、10%硅藻土、10%可溶性淀粉、6%复合稳定剂、70%十水硫酸钠的配方制成洗涤用酶颗粒制剂. 酶颗粒制剂的主要酶种类与酶活性与市售商品洗涤用酶制剂一致,可用于作洗涤的酶添加剂. ...
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Descriere Este un detergent pulbere, care poate fi utilizat pentru prespalare si spalare. Recomandat pentru curatarea tesaturilor colorate. Indeparteaza eficient murdaria persistenta, uleiurile si grasimile. Contine enzime. Nu contine clor sau inalbitori optici.. Mod de ambalare: pachet 18 kg.. ...
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Detergent pentru lemn, progesional, confectionat pe baza unui amestec de uleiuri exotice si extrase radacinoase, ce ajuta la recapatarea luciului supr...
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We couldnt find any Triton X-100 in the lab. Our best guess is that NP-40 was (previously) used instead. -Jkm 18:18, 2 August 2006 (EDT ...
Świadczymy usługi prania tapicerki meblowej i samochodowej. Usługę wykonujemy w lokalizacji klienta. Wyprane przez nas meble są natychmiast suche i gotowe do użytku. ...
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A functionally diverse set of cell surface proteins, including receptors, adhesion molecules, and enzymes, become insoluble to extraction in the detergent Triton X-100 as they traverse the secretory pathway and are delivered to the plasma membrane (PM). Acquisition of resistance to detergent extraction is thought to correspond to assembly into stable microdomains, which can be conceptualized as lipid rafts floating in the membrane (Simons and Ikonen 1997; Pralle et al. 2000). Purification of detergent-resistant membranes shows that they are enriched in sterols, glycosphingolipids, sphingolipids, saturated phospholipids, and glycosyl phosphatidyl inositol (GPI)-anchored proteins (Simons and Ikonen 1997; Brown and London 1998). Lipid rafts, as defined by detergent resistance, have been associated with sorting of proteins bound for the cell surface during exit from the Golgi complex, as well as with organization of signaling molecules on the cell surface (Simons and Ikonen 1997; Stauffer and Meyer ...
A major mouse T-lymphoma surface glycoprotein (gp180) has been identified by labeling cells with 125I and [3H]glucosamine. After ligand-induced receptor patching and/or capping, the amount of gp 180 in the membrane-associated cytoskeleton fraction increases in direct proportion to the percentage of patched/capped cells. There is a parallel increase in the amount of fodrin in the membrane-associated cytoskeleton fraction. Evidence is presented that gp180 is the same as or very similar to the T-lymphocyte-specific glycoprotein T-200. An immunobinding assay of Nonidet P-40-solubilized plasma membrane selectively co-isolates gp180 and fodrin. After induction of receptor rearrangement, double-label immunofluorescence reveals that fodrin accumulated directly beneath gp180 patches and caps. Membrane extraction with Triton X-114 followed by sucrose gradient centrifugation permits isolation of a gp180-fodrin complex with a 1:1 molar ratio and sedimentation coefficient(s) of approximately 20. This complex ...
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There is provided herein a membrane or film comprising one or more aromatic ionomers covalently crosslinked through aryl-aryl (--Ar--Ar--), aryl-ether-aryl (--Ar--O--Ar--), aryl-sulfide-aryl (--Ar--S--Ar--), aryl-sulfone-aryl bonds, or any combination thereof, wherein said one or more aromatic ionomers further comprises at least one electron withdrawing group adapted to improve oxidant resistance of said membrane or film.
Distorted bands from human colon samples - posted in SDS-PAGE and Western Blotting: I have been running western blots for some time now and I am having difficulty running some human colon samples that perhaps I could get advice on. In brief my protocol is as follows: To 0.12g of colon tissue, I add 1ml of RIPA (0.96g Tris, 3.5g NaCL, 0.24g EDTA, 0.3g EGTA, 4g Na Doxycholate, 4ml Triton-X 100, 4ml 10% SDS, made up to 400ml with dH2). I leave the tissue in RIPA for 10 mins on ice, after whic...
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Efficient ethanol plants can convert 90-97 percent of the corns starch content to ethanol. However, not all batches of corn leave the same amount of starch residue. Studies of ethanol yields from different batches show significant variability (Dien et al., March 2002). Even though it is the starch that is turned into ethanol, researchers have been unable to find a correlation between starch content (or even starch extractability) and the final yield of ethanol (Singh and Graeber). Researchers believe some starches are in a more available form (Dien et al., March 2002). ...
Check Analytical Biochemistry 53, 304-308 (1973) and 109, 207-215 (1980). Lena. Markus Zettl wrote: , Markus Zettl schrieb: , , , , I solubilized membrane proteins by Triton X-100 and for further , , aplications I want to get rid of this detergent. Could you tell me a way , , to remove Triton X-100 from my probes leaving membrane proteins in , , native conformation. , , Thanks. -------------- next part -------------- An HTML attachment was scrubbed... URL: http://iubio.bio.indiana.edu/bionet/mm/proteins/attachments/19980129/63198f2c/attachment.html ...
Northstar offers a complete line of highly concentrated biodegradable cleaning detergents at cost-effective prices. We often find that many people are using far more detergent than they need to clean even the dirtiest jobs. Are you using too much? We can help you determine what your cost per application is. Let us know what you are cleaning and our team will help with a recommendation - if you do not see what you are looking for on this list, let us know. We have many options that may not be listed.. ...
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Detergent on pesemiseks ja puhastamiseks ettenähtud aine või segu, mis sisaldab pindaktiivseid aineid ning on mõeldud kasutamiseks koduses majapidamises või institutsioonilistel või tööstuslikel eesmärkidel ...
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Synthetic Detergent Definition - A synthetic detergent is any synthetic substance, other than soap, that is an effective cleanser and functions...
United States: Revenue in the Dishwashing Detergents segment amounts to US$2,637m in 2020. The market is expected to grow annually by 1.7% (CAGR 2020-2023). The Dishwashing Detergents segment covers cleaning products used for washing up and cleaning dishes and cutlery.
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Detergent dezinfectant Evans E-Phos 5L - acid, parfumat, pentru indepartarea depunerilor de piatra, grasimi si murdarie din grupurile sanitare si piscine. ...
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Fast, efficient, thorough and resource-saving: high-pressure cleaning, in combination with perfectly coordinated cleaning agents, is also impressive in the case of very demanding cleaning tasks.. ...
The very fact that SocGen issues notes about geopolitics, and uses the term itself, to an extent solidifies the link between finance and geopolitics.
Aquafresh Active White 125ml Contine microparticule cu efect de albire ce confera dintilor un alb vizibil mai intens, formand o bariera invizibila
Prin navigarea siteului sunt de acord cu prelucrarea datelor cu caracter personal, in conformitate cu Regulamentul general privind protectia datelor („GDPR).OkTermeni si Conditii ...
Read 31 responses to: My daughter is almost 2 yrs old and I was just... Find the best answer on Mamapedia - mom trusted since 2006.
هاند سوب 4 لتر (منظف ايدى ذو رائحة مميزة و رغوة وفيرة يستخدم لتنظيف الوجه والايدى يحتوى على مواد منعمة للبشرة. يتم إضافة 40 جنيه مصاريف شحن داخل القاهرة والجيزة. ...
4O)n) is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. It is closely related to IGEPAL CA-630 or erstwhile Nonidet P-40, which might differ from it mainly in having slightly shorter ethylene oxide chains. Thus Triton X-100 is slightly more hydrophilic than Igepal CA-630; these two detergents may not be considered to be functionally interchangeable for most applications.[2] Triton X-100 was originally a registered trademark of Rohm & Haas Co. It was subsequently purchased by Union Carbide and then acquired by Dow Chemical Company upon the acquisition of Union Carbide. Soon afterward (in 2009), Dow also acquired Rohm & Haas Co. Other trademarks for very similar compounds include Conco NI, Dowfax 9N, Igepal CO, Makon, Neutronyx 600's, Nonipol NO, Plytergent B, Renex 600's, Solar NO, Sterox, Serfonic N, ...
Octoxynol-9 was previously a common spermicide, but was removed from the U.S. market in 2002 after manufacturers failed to ... Active secondary spermicidal ingredients can include octoxynol-9, benzalkonium chloride and menfegol. These secondary ...
... octoxynol MeSH D25.720.741.650 - poloxalene MeSH D25.720.741.667 - poloxamer MeSH D25.720.741.685 - polyhydroxyethyl ...
... octoxynol MeSH D05.750.741.650 - poloxalene MeSH D05.750.741.667 - poloxamer MeSH D05.750.741.685 - polyhydroxyethyl ...
About OCTOXYNOL-9: Octoxynol-9 is an ethoxylated alkyl phenol.. Function(s): Surfactant - Emulsifying Agent; CLEANSING ...
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWGs strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...
Octoxynols (Octoxynol-1, Octoxynol-3, Octoxynol-5, Octoxynol-6, Octoxynol-7, Octoxynol-8, Octoxynol-9, Octoxynol-10, Octoxynol- ... 11, Octoxynol-12, Octoxynol-13, Octoxynol-16, Octoxynol-20, Octoxynol-25, Octoxynol-30, Octoxynol-33, Octoxynol-40, Octoxynol- ... Sodium Octoxynol-2 Ethane Sulfonate, Sodium Octoxynol-2 Sulfate, Sodium Octoxynol-6 Sulfate, Sodium Octoxynol-9 Sulfate) are a ... Octoxynol-9 Carboxylic Acid, Octoxynol-20 Carboxylic Acid, Potassium Octoxynol-12 Phosphate, and Sodium Octoxynol-9 Sulfate ...
... February 16, 2009 , Contact Author , By: Charles Fox, Independent ... Keywords: patents , octoxynol Abstract: Skin-warming foam: Pola Chemical Industries discloses skin-warming cosmetic foam ...
Sodium octoxynol sulfate - Surfactant - SAAPedia - SAAPedia(Surfactant.TOP),Surfactant,Anionic surfactants, Cationic ...
For octoxynol 9. * For preventing pregnancy: * For vaginal dosage form (cream): * Adults and teenagers- * For use with a ...
4O)n) is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. It is closely related to IGEPAL CA-630 or erstwhile Nonidet P-40, which might differ from it mainly in having slightly shorter ethylene oxide chains. Thus Triton X-100 is slightly more hydrophilic than Igepal CA-630; these two detergents may not be considered to be functionally interchangeable for most applications.[2] Triton X-100 was originally a registered trademark of Rohm & Haas Co. It was subsequently purchased by Union Carbide and then acquired by Dow Chemical Company upon the acquisition of Union Carbide. Soon afterward (in 2009), Dow also acquired Rohm & Haas Co. Other trademarks for very similar compounds include Conco NI, Dowfax 9N, Igepal CO, Makon, Neutronyx 600s, Nonipol NO, Plytergent B, Renex 600s, Solar NO, Sterox, Serfonic N, ...
... octoxynol; octoxynol-9; octyl dimethyl PABA; octyl methoxycinnamate; omega-3 polyunsaturated fatty acids; omeprazole; ...
Octoxynol-9:. Octoxynol-9 is a potent contraceptive drug that effectively kills sperm. However, wipes containing octoxynol-9 ... Use of octoxynol-9 in spermicides has been associated with genital irritation and increased vaginal discharge [12]. Octoxynol-9 ...
Octoxynol 9. (29) Sunscreen drug products. (i) Ingredients. Diethanolamine methoxycinnamate Digalloyl trioleate ...
ii) Any ingredients labeled with any of the following or similar claims. Instant protection or protection immediately upon application. Claims for "all-day" protection or extended wear claims citing a specific number of hours of protection that is inconsistent with the directions for application in 21 CFR 201.327. (30) [Reserved] (b) Any OTC drug product that is labeled, represented, or promoted for the uses specified and containing any active ingredient(s) as specified in paragraph (a) of this section is regarded as a new drug within the meaning of section 210(p) of the Federal Food, Drug, and Cosmetic Act (the Act), for which an approved new drug application under section 505 of the Act and part 314 of this chapter is required for marketing. In the absence of an approved new drug application, such product is also misbranded under section 502 of the Act. (c) Clinical investigations designed to obtain evidence that any drug product labeled, represented, or promoted for the OTC uses and ...
Spermicidal agents octoxynol 1-5% or nonoxyl 3-15%ascorbic acid 1-5%Carrier system:propylene glycol 1-5%stearic acid 1-5% ...
Each 0.5-mL dose also contains octoxynol-10 (TRITON® X-100) ≤0.085 mg, α-tocopheryl hydrogen succinate ≤0.1 mg, and polysorbate ...
water, octoxynol-9, sodium citrate, polysorbate 20, propylene glycol, citric acid, diazolidinyl urea, polyquaternium-4, benzyl ...
Octoxynol-9; Denatonium BenzoateUses:Restores lost color to gray hair, gradually. Natural-looking color: Day by day, Grecian ...
... octoxynol 40; purified water; sodium chloride; hydrochloric acid and/or sodium hydroxide to adjust the pH. ...
Look for one that has octoxynol-9. Another common spermicide, nonoxynol-9, can irritate the genitals, which may increase the ...
Octoxynol / pharmacology * Phosphorylation * Precipitin Tests * Protein Synthesis Inhibitors / pharmacology * S-Phase Kinase- ...
Octoxynol. Oligodendroglia / chemistry*, physiology*, ultrastructure. Optic Nerve / chemistry, cytology, physiology. Phenotype ...
... octoxynol-9, purified water, sodium hyaluronate, soluble collagen and trolamine. ... octoxynol-9, purified water, sodium hyaluronate, soluble collagen and trolamine. ...
OCTOXYNOL 9 (UNII: 7JPC6Y25QS). Packaging. #. Item Code. Package Description. Marketing Start Date. Marketing End Date. ...
Octoxynol / pharmacology. Phosphatidylserines / metabolism. Phospholipases / chemistry*, genetics. Plasmids / metabolism. ... 0/Cations; 0/Detergents; 0/Phosphatidylserines; 0/Saccharomyces cerevisiae Proteins; 0/Sphingolipids; 9002-93-1/Octoxynol; EC ...
Octoxynol-2 View Synonyms. View Structure. Detailed Summary. * Info Biological activities and chemical structures (PubChem) ...
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Octoxynol); EC 1.- (Oxidoreductases); EC 1.1.1.57 (Fructuronate Reductase); EC 1.3.3.6 (Acyl-CoA Oxidase); EC 2.3.1.9 (Acetyl- ...
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Octoxynol-9. Propylene Glycol. Sodium Lactate Massengill Disposable - GlaxoSmithKline Cetylpyridinium Chloride. Alcohol. ...
Octoxynol-9. Vinegar New Freshness - C.B. Fleet Sorbic Acid. Polyethylene Glycol. Sodium Citrate. Sodium Lauryl Sulfate. ... Octoxynol-9. Sodium Benzoate Feminique - Quality Health Products Sorbic Acid. ...
  • In my lab days, I always wondered about the wisdom of using nonoxynol-9 as a spermatocide because we used to use a related compound, octoxynol-9 (better known to labbies as Triton X-100), to break open human epithelial cancer cells to examine the proteins inside them. (forbes.com)
  • Women who used Nonoxynol-9 or Octoxynol-9 as spermicides, but became pregnant, did not have an increase in the overall risk of fetal malformations. (cosmeticsinfo.org)
  • 6 . A device according to claim 5 wherein the spermicidal agent is selected from the group consisting of: nonoxynol-9, octoxynol-9, menfegol, benzalkonium chloride and N-docasanol. (google.es)
  • Its efficacy is improved in conjunction spermicides are nonoxynol-9 (N-9), octoxynol-9, menfegol, with mechanical barrier methods such as condom, and benzalkonium chloride. (who.int)
  • The Octoxynol salts and organic acids are then produced from these Octoxynol compounds. (cosmeticsinfo.org)
  • Active secondary spermicidal ingredients can include octoxynol-9, benzalkonium chloride and menfegol. (wikipedia.org)
  • The CIR Expert Panel also concluded that Octoxynol-1, -3, -5, -6, -7, and -8, Sodium Octoxynol-2 Ethane Sulfonate, Sodium Octoxynol-2 Sulfate, and Sodium Octoxynol-6 Sulfate were safe in rinse-off products and safe at concentrations of 5% or less in leave-on products. (cosmeticsinfo.org)
  • Vaccines contain many ingredients that are potentially damaging to fertility including detergents like triton X-100, also known as octoxynol 10 which is a known spermicide and has been used in experiments to "strip" sperm so that they are no longer capable of fertilizing an egg. (drbloem.com)
  • Potassium Octoxynol-12 Phosphate has the ability to enhance the water solubility of other surfactants. (cosmeticsinfo.org)
  • The manufacturing process includes treatment with an organic solvent/detergent mixture, 1,2 composed of tri-n-butyl phosphate, octoxynol 9 and polysorbate 80. (rxlist.com)
  • Stabilizing agents and additional components are present in the following maximum amounts for a 5% solution: 3 mg/mL Albumin (Human), 22.5 mg/mL glycine , 20 mg/mL glucose , 2 mg/mL polyethylene glycol (PEG), 1 µg/mL tri-n-butyl phosphate, 1 µg/mL octoxynol 9, and 100 µg/mL polysorbate 80. (rxlist.com)
  • Octoxynol-8, purified water and sodium phosphate tribasic. (tevacanada.com)
  • Octoxynol-9 was previously a common spermicide, but was removed from the U.S. market in 2002 after manufacturers failed to perform new studies required by the FDA. (wikipedia.org)
  • Dermal exposure at three dose levels to Octoxynol-9 failed to induce any developmenta effects. (cosmeticsinfo.org)
  • Each 0.5-mL dose also contains octoxynol-10 (TRITON X-100) .0.085 mg, -tocopheryl hydrogen succinate .0.1 mg, and polysorbate 80 (Tween 80) .0.415 mg. (whale.to)
  • Octoxynol-9 is an ethoxylated alkyl phenol. (ewg.org)
  • Octoxynol 10 (Triton X-100) is contained in vaccines. (drbloem.com)
  • Many of the Octoxynols, and the Octoxynol acids and salts, clean skin and hair by helping water to mix with oil and dirt so that they can be rinsed away. (cosmeticsinfo.org)
  • No reproductive toxicity was seen in males which received 5% Octoxynol-40 in the diet daily for three months. (cosmeticsinfo.org)
  • In a human skin irritation study, formulations containing 2% Octoxynol-9 were classified as moderately irritating and minimally irritating, respectively, in a 24-hour single-insult, occlusive patch test. (cosmeticsinfo.org)
  • Octoxynols vary in chain length from Octoxynol-1 to Octoxynol-70. (cosmeticsinfo.org)
  • Il s'agit d'une source d'informations unique sur les substances chimiques fabriquées et importées en Europe. (europa.eu)
  • Show all 1 recent products that contain OCTOXYNOL-9. (ewg.org)
  • Last week, an article at Chemical & Engineering News (C&EN), the official organ of the American Chemical Society, delved into the chemistry and safety of these intimate use products. (forbes.com)
  • Written by Dr. Lauren K. Wolf ( @laurenkwolf ), C&EN associate editor and laser chemistry PhD, "Studies Raise Questions About Safety Of Personal Lubricants," discusses recent research on the potential for some products to damage delicate tissue or increase the risks of infectious disease transmission. (forbes.com)
  • The C&EN team took three papers discussed by Wolf and created this graph for some common brands of personal lubricants. (forbes.com)
  • What do Polysorbate 80 and Octoxynol 10 have in common? (drbloem.com)
  • For example, Octoxynol-9 is made by reacting p-(1,1,3,3-tetraemethylbutyl)phenol with 5-18 units of ethylene oxide, resulting in an average value of 9. (cosmeticsinfo.org)
  • No significant effects were noted in short-term oral studies of Octoxynol-9, in subchronic oral studies of Octoxynol-40, or in chronic oral studies of Octoxynol-40. (cosmeticsinfo.org)