Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)
Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).
Cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. Can cause local irritation.
An absorbable suture material used also as ligating clips, as pins for internal fixation of broken bones, and as ligament reinforcement for surgically managed ligament injuries. Its promising characteristics are elasticity, complete biodegradability, and lack of side effects such as infections.
Amino derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the amino caproic acid structure.
Enzymes which are immobilized on or in a variety of water-soluble or water-insoluble matrices with little or no loss of their catalytic activity. Since they can be reused continuously, immobilized enzymes have found wide application in the industrial, medical and research fields.
A genus of gram-negative, aerobic, rod-shaped bacteria widely distributed in SOIL and WATER. Its organisms are also found in raw meats, MILK and other FOOD, hospital environments, and human clinical specimens. Some species are pathogenic in humans.
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.
A polyester used for absorbable sutures & surgical mesh, especially in ophthalmic surgery. 2-Hydroxy-propanoic acid polymer with polymerized hydroxyacetic acid, which forms 3,6-dimethyl-1,4-dioxane-dione polymer with 1,4-dioxane-2,5-dione copolymer of molecular weight about 80,000 daltons.
Fastening devices composed of steel-tantalum alloys used to close operative wounds, especially of the skin, which minimizes infection by not introducing a foreign body that would connect external and internal regions of the body. (From Segen, Current Med Talk, 1995)
An encapsulated lymphatic organ through which venous blood filters.
Pathologic process consisting of a partial or complete disruption of the layers of a surgical wound.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.
Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.
Adherence of cells to surfaces or to other cells.
A group of compounds having the general formula CH2=C(CN)-COOR; it polymerizes on contact with moisture; used as tissue adhesive; higher homologs have hemostatic and antibacterial properties.
Polymers where the main polymer chain comprises recurring amide groups. These compounds are generally formed from combinations of diamines, diacids, and amino acids and yield fibers, sheeting, or extruded forms used in textiles, gels, filters, sutures, contact lenses, and other biomaterials.
The outer margins of the ABDOMEN, extending from the osteocartilaginous thoracic cage to the PELVIS. Though its major part is muscular, the abdominal wall consists of at least seven layers: the SKIN, subcutaneous fat, deep FASCIA; ABDOMINAL MUSCLES, transversalis fascia, extraperitoneal fat, and the parietal PERITONEUM.
Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The process of breakdown of food for metabolism and use by the body.
Polyester polymers formed from terephthalic acid or its esters and ethylene glycol. They can be formed into tapes, films or pulled into fibers that are pressed into meshes or woven into fabrics.
A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.
The in vitro formation of clusters consisting of a cell (usually a lymphocyte) surrounded by antigenic cells or antigen-bearing particles (usually erythrocytes, which may or may not be coated with antibody or antibody and complement). The rosette-forming cell may be an antibody-forming cell, a memory cell, a T-cell, a cell bearing surface cytophilic antibodies, or a monocyte possessing Fc receptors. Rosette formation can be used to identify specific populations of these cells.
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the cytoplasm is typically pale blue with azurophilic (if any) granules. Most lymphocytes can be classified as either T or B (with subpopulations of each), or NATURAL KILLER CELLS.
One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.
Procedures for collecting, preserving, and transporting of specimens sufficiently stable to provide accurate and precise results suitable for clinical interpretation.
The first stomach of ruminants. It lies on the left side of the body, occupying the whole of the left side of the abdomen and even stretching across the median plane of the body to the right side. It is capacious, divided into an upper and a lower sac, each of which has a blind sac at its posterior extremity. The rumen is lined by mucous membrane containing no digestive glands, but mucus-secreting glands are present in large numbers. Coarse, partially chewed food is stored and churned in the rumen until the animal finds circumstances convenient for rumination. When this occurs, little balls of food are regurgitated through the esophagus into the mouth, and are subjected to a second more thorough mastication, swallowed, and passed on into other parts of the compound stomach. (From Black's Veterinary Dictionary, 17th ed)
A vinyl polymer made from ethylene. It can be branched or linear. Branched or low-density polyethylene is tough and pliable but not to the same degree as linear polyethylene. Linear or high-density polyethylene has a greater hardness and tensile strength. Polyethylene is used in a variety of products, including implants and prostheses.
Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.
Procedure whereby plasma is separated and extracted from anticoagulated whole blood and the red cells retransfused to the donor. Plasmapheresis is also employed for therapeutic use.
Restoration of integrity to traumatized tissue.
An enzyme of the oxidoreductase class that catalyzes the conversion of beta-D-glucose and oxygen to D-glucono-1,5-lactone and peroxide. It is a flavoprotein, highly specific for beta-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide produced in the reaction. (From Enzyme Nomenclature, 1992) EC 1.1.3.4.
Lymphoid cells concerned with humoral immunity. They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation.
Method of analyzing chemicals using automation.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
T-cell enhancement of the B-cell response to thymic-dependent antigens.
Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION.
A series of steps taken in order to conduct research.
Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.
The maximum stress a material subjected to a stretching load can withstand without tearing. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed, p2001)
A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.
Foodstuff used especially for domestic and laboratory animals, or livestock.
Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)
The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.
Elements of limited time intervals, contributing to particular results or situations.
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
Infection occurring at the site of a surgical incision.
Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
Substances that are recognized by the immune system and induce an immune reaction.
The demonstration of the cytotoxic effect on a target cell of a lymphocyte, a mediator released by a sensitized lymphocyte, an antibody, or complement.
White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).
Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
Deoxyribonucleic acid that makes up the genetic material of bacteria.
The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)
Serum containing GAMMA-GLOBULINS which are antibodies for lymphocyte ANTIGENS. It is used both as a test for HISTOCOMPATIBILITY and therapeutically in TRANSPLANTATION.
Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.
Chemical substances that attract or repel cells. The concept denotes especially those factors released as a result of tissue injury, microbial invasion, or immunologic activity, that attract LEUKOCYTES; MACROPHAGES; or other cells to the site of infection or insult.
Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell.
A species of mosquito in the genus Anopheles and the principle vector of MALARIA in Africa.
A group of differentiation surface antigens, among the first to be discovered on thymocytes and T-lymphocytes. Originally identified in the mouse, they are also found in other species including humans, and are expressed on brain neurons and other cells.
Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER).
Microscopy in which the object is examined directly by an electron beam scanning the specimen point-by-point. The image is constructed by detecting the products of specimen interactions that are projected above the plane of the sample, such as backscattered electrons. Although SCANNING TRANSMISSION ELECTRON MICROSCOPY also scans the specimen point by point with the electron beam, the image is constructed by detecting the electrons, or their interaction products that are transmitted through the sample plane, so that is a form of TRANSMISSION ELECTRON MICROSCOPY.
Proteins that share the common characteristic of binding to carbohydrates. Some ANTIBODIES and carbohydrate-metabolizing proteins (ENZYMES) also bind to carbohydrates, however they are not considered lectins. PLANT LECTINS are carbohydrate-binding proteins that have been primarily identified by their hemagglutinating activity (HEMAGGLUTININS). However, a variety of lectins occur in animal species where they serve diverse array of functions through specific carbohydrate recognition.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.
Substances that stimulate mitosis and lymphocyte transformation. They include not only substances associated with LECTINS, but also substances from streptococci (associated with streptolysin S) and from strains of alpha-toxin-producing staphylococci. (Stedman, 25th ed)
Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
The reduction or regulation of the population of mosquitoes through chemical, biological, or other means.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.
A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
An increased reactivity to specific antigens mediated not by antibodies but by cells.
Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.
Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.
Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.
The number of WHITE BLOOD CELLS per unit volume in venous BLOOD. A differential leukocyte count measures the relative numbers of the different types of white cells.
The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.
CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.
Characteristics or attributes of the outer boundaries of objects, including molecules.
The movement of leukocytes in response to a chemical concentration gradient or to products formed in an immunologic reaction.
Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed)
A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.
A single, unpaired primary lymphoid organ situated in the MEDIASTINUM, extending superiorly into the neck to the lower edge of the THYROID GLAND and inferiorly to the fourth costal cartilage. It is necessary for normal development of immunologic function early in life. By puberty, it begins to involute and much of the tissue is replaced by fat.
Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
The rate dynamics in chemical or physical systems.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.
They are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.
Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.
The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.
Any liquid or solid preparation made specifically for the growth, storage, or transport of microorganisms or other types of cells. The variety of media that exist allow for the culturing of specific microorganisms and cell types, such as differential media, selective media, test media, and defined media. Solid media consist of liquid media that have been solidified with an agent such as AGAR or GELATIN.
A method (first developed by E.M. Southern) for detection of DNA that has been electrophoretically separated and immobilized by blotting on nitrocellulose or other type of paper or nylon membrane followed by hybridization with labeled NUCLEIC ACID PROBES.
Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.
The functional hereditary units of BACTERIA.
Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.
The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Established cell cultures that have the potential to propagate indefinitely.
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.

Interleukin-10 and antigen-presenting cells actively suppress Th1 cells in BALB/c mice infected with the filarial parasite Brugia pahangi. (1/451)

Infection with the third-stage larvae (L3) of the filarial nematode Brugia results in a Th2-biased immune response in mice and humans. Previously we have shown that the production of interleukin 4 (IL-4) is critical for down-regulating polyclonal Th1 responses in L3-infected mice. However, the in vitro neutralization of IL-4 did not fully recover the defective polyclonal Th1 responses, nor did it result in the production of any antigen (Ag)-specific Th1 cytokines, suggesting that perhaps infection with L3 does not result in priming of Th1 cells in vivo. In this study, we analyzed the role of IL-10 and Ag-presenting cells (APCs) in the spleen as additional factors controlling the Th2 bias in infected mice. Our data show that IL-10 and APCs also contribute to the suppression of mitogen-driven Th1 responses of spleen cells from infected mice. In addition, the neutralization of IL-10 or the replacement of the resident APC population from spleen cell cultures resulted in the production of Ag-specific Th1 cytokines. Irradiated spleen cells from either L3-infected or uninfected mice were able to restore Ag-specific Th1 responses in vitro. Therefore, it appears that Brugia-reactive Th1 cells are primed following infection with L3, but are actively suppressed in vivo by a mechanism that involves IL-10 and the resident APC population, but not IL-4. These results indicate that a complex interplay of cytokines and cell populations underscores the Th2-polarized response in L3-infected mice.  (+info)

Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. (2/451)

Sequence-specific pyrrole-imidazole polyamides can be designed to interfere with transcription factor binding and to regulate gene expression, both in vitro and in living cells. Polyamides bound adjacent to the recognition sites for TBP, Ets-1, and LEF-1 in the human immunodeficiency virus, type 1 (HIV-1), long terminal repeat inhibited transcription in cell-free assays and viral replication in human peripheral blood lymphocytes. The DNA binding activity of the transcription factor Ets-1 is specifically inhibited by a polyamide bound in the minor groove. Ets-1 is a member of the winged-helix-turn-helix family of transcription factors and binds DNA through a recognition helix bound in the major groove with additional phosphate contacts on either side of this major groove interaction. The inhibitory polyamide possibly interferes with phosphate contacts made by Ets-1, by occupying the adjacent minor groove. Full-length Ets-1 binds the HIV-1 enhancer through cooperative interactions with the p50 subunit of NF-kappaB, and the Ets-inhibitory polyamide also blocks formation of ternary Ets-1. NF-kappaB.DNA complexes on the HIV-1 enhancer. A polyamide bound adjacent to the recognition site for NF-kappaB also inhibits NF-kappaB binding and ternary complex formation. These results broaden the application range of minor groove-binding polyamides and demonstrate that these DNA ligands are powerful inhibitors of DNA-binding proteins that predominantly use major groove contacts and of cooperative protein-DNA ternary complexes.  (+info)

Sensitivity issues in DNA array-based expression measurements and performance of nylon microarrays for small samples. (3/451)

DNA or oligonucleotide arrays are widely used for large-scale expression measurements, using various implementations: macroarrays in which DNA is spotted onto nylon membranes of relatively large dimensions (with radioactive detection) on the one hand; microarrays on glass slides and oligonucleotide chips, both used with fluorescent probes, on the other hand. Nylon micro-arrays with colourimetric detection have also been described recently. The small physical dimensions of miniaturized systems allow small hybridization volumes (2-100 microl) and provide high probe concentrations, in contrast to macroarrays. We show, however, that actual sensitivity (defined as the amount of sample necessary for detection of a given mRNA species) is in fact similar for all these systems and that this is mostly due to the very different amounts of target material present on the respective arrays. We then demonstrate that the combination of nylon microarrays with(33)P-labelled radioactive probes provides 100-fold better sensitivity, making it possible to perform expression profiling experiments using submicrogram amounts of unamplified total RNA from small biological samples. This has important implications in basic and clinical research and makes this alternative approach particularly suitable for groups operating in an academic context.  (+info)

Functional and morphologic characteristics of the leukemic cells of a patient with acute monocytic leukemia: correlation with clinical features. (4/451)

The clinical course of a patient with acute monocytic leukemia and prominent infiltration of the skin and testes is described. In vitro studies demonstrated that the circulating monocyte precursors were capable of adherence to nylon fibers, and phagocytosis of bacteria and latex particles. In vivo, migration of leukemic cells to skin windows was observed. Extreme nuclear folding, marked surface activity, and morphologic features suggesting nuclear and cytoplasmic maturation were seen by light and electron microscopy. The presence of morphologically and functionally more differentiated monocytic cells may account for the marked tiuuse invasion in this patient and, possibly, in other patients with monocytic leukemia.  (+info)

In vitro cytotoxicity of textile paint components linked to the "Ardystil syndrome". (5/451)

The spraying of a paint formula (Acramin F system) had led to severe pulmonary disease in textile printing sprayers in Spain and Algeria (Ardystil syndrome). In order to elucidate the underlying mechanisms of the toxicity of this paint and its main polymeric components, Acramin FWR, Acramin FWN, Acrafix FHN, and Acramoll W, we have undertaken studies using a battery of different cell-types and assessing in vitro cytotoxicity by measuring LDH leakage. This study shows that, as in in vivo studies, the three polycationic paint components, Acramin FWR (a polyurea), Acramin FWN (a polyamide-amine), and Acrafix FHN (a polyamine) exhibited considerable cytotoxicity (LC50 generally below 100 microg/ml for an incubation of 20-24 h) in vitro, while Acramoll W, which is not a polycation, was almost non-toxic (in the concentration range tested). The cytotoxicity was comparable in primary cultures of rat and human type II pneumocytes and alveolar macrophages as well as in the pulmonary cell line A549 and the hepatic cell line HepG2. In human erythrocytes, the toxicity was less pronounced. We speculate that the multiple positive charges play an important role in the toxic mechanism. It is concluded that Acramin FWR and Acramin FWN have similar intrinsic toxicity and that these polymeric compounds, which have no irritant properties or systemic toxicity when given orally, exert a high, unexpected, degree of cytotoxicity.  (+info)

Local anaesthetic effect of topical amethocaine gel in neonates: randomised controlled trial. (6/451)

AIM: To assess the efficacy of amethocaine as a topical local anaesthetic in neonates. METHODS: A randomised, double blind controlled trial compared 4% amethocaine gel (Ametop) with placebo in 60 healthy neonates (29 to 42 weeks of gestation) in the first week after birth. Either 1.5 g 4% w/w amethocaine (gel) or 1.5 g placebo gel were applied to the dorsum of one foot. No gel was applied to the other foot. Each foot was occluded and left for one hour. Local anaesthesia was then assessed by eliciting the cutaneous withdrawal reflex in response to stimulation with a series of graded nylon filaments (von Frey hairs). The reflex was first elicited from the control and then the treated foot. The difference in filament thickness and deforming weight required to elicit the reflex was recorded. RESULTS: In infants treated with amethocaine, 17 of 31 (54. 8%) showed evidence of local anaesthetic action compared with five of 29 (17.2%) in the placebo group (p=0.003). The mean difference in deforming weight required to elicit the reflex was 18.8 g in the amethocaine group compared with 3.9 g in the placebo group (p=0.02). The apparent local anaesthetic action of the placebo can be explained by habituation to repeated stimulation. CONCLUSIONS: It is concluded that topical amethocaine gel has a local anaesthetic action on neonatal skin which merits further investigation. An effective and safe surface local anaesthetic would be valuable for the relief of procedure related pain in neonates.  (+info)

In-source decay of hyperbranched polyesteramides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. (7/451)

Hyperbranched polyesteramides (DA2), prepared from hexahydrophthalic anhydride (D) and diisopropanolamine (A) have been characterized, by use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), field desorption (FD)-MS, and electrospray ionization (ESI)-MS. MALDI of polyesteramides produces protonated molecules. The spectra show a complex chemical composition distribution and end-group distribution which are mainly composed of two series of homologous oligomers DnA(n)+1 - mH2O and DnA(n) - mH2O, where m = 1-2. Signals from protonated molecules DnAn+1 and DnAn are almost absent in the MALDI spectrum, whereas these ions are responsible for the base peak of DnA(n)+1 - mH2O and DnA(n) - mH2O (m = 1-2) clusters in the ESI spectrum. The absence of -OH end-groups signals in the MALDI spectrum is due to a metastable decay of protonated DnA(n)+1 and DnAn ions in the ion source of the MALDI mass spectrometer prior to ion extraction. In-source decay results in the formation of protonated lower DnA(n)+1 - mH2O and DnA(n) - mH2O oligomers and their corresponding neutrals, leading to wrong conclusions concerning the relative end-group distribution as a function of the degree of polymerization and the chemical composition.  (+info)

Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates. (8/451)

BACKGROUND: Pyrrole-imidazole polyamides are synthetic ligands that recognize predetermined sequences in the minor groove of DNA with affinities and specificities comparable to those of DNA-binding proteins. As a result of their DNA-binding properties, polyamides could deliver reactive moieties for covalent reaction at specific DNA sequences and thereby inhibit DNA-protein interactions. Site-specific alkylation of DNA could be a useful tool for regulating gene expression. As a minimal first step, we set out to design and synthesize a class of hairpin polyamides equipped with DNA alkylating agents and characterize the specificity and yield of covalent modification. RESULTS: Bis(dichloroethylamino)benzene derivatives of the well-characterized chlorambucil (CHL) were attached to the gamma turn of an eight-ring hairpin polyamide targeted to the HIV-1 promoter. We found that a hairpin polyamide-CHL conjugate binds and selectively alkylates predetermined sites in the HIV promoter at subnanomolar concentrations. Cleavage sites were determined on both strands of a restriction fragment containing the HIV-1 promoter, revealing good specificity and a high yield of alkylation. CONCLUSIONS: The ability of polyamide-CHL conjugates to sequence specifically alkylate double-stranded DNA in high yield and at low concentrations sets the stage for testing their use as regulators of gene expression in cell culture and ultimately in complex organisms.  (+info)

We investigated sequence-specific DNA alkylation using conjugates between the N-methylpyrrole (Py)-N-methylimidazole (Im) polyamide and the DNA alkylating agent, chlorambucil, or 1-(chloromethyl)-5-hydroxy-1, 2-dihydro-3H-benz[e]indole (seco-CBI). Polyamide-chlorambucil conjugates 1-4 differed in the position at which the DNA alkylating chlorambucil moiety was bound to the Py-Im polyamide. High-resolution denaturing polyacrylamide gel electrophoresis (PAGE) revealed that chlorambucil conjugates 1-4 alkylated DNA at the sequences recognized by the Py-Im polyamide core moiety. Reactivity and sequence specificity were greatly affected by the conjugation position, which reflects the geometry of the alkylating agent in the DNA minor groove. Polyamide-seco-CBI conjugate 5 was synthesized to compare the efficacy of chlorambucil with that of seco-CBI as an alkylating moiety for Py-Im polyamides. Denaturing PAGE analysis revealed that DNA alkylation activity of polyamide-seco-CBI conjugate 5 was similar ...
A new upper limit of binding site size is defined for the 2:1 overlapped polyamide:DNA motif. Eight-ring polyamides composed of four-ring subunits containing pyrrole (Py) and imidazole (Im) amino acids linked by a central beta-alanine (beta) spacer (4-beta-4 ligands) were designed for recognition of eleven base pair sequences as antiparallel dimer (4-beta-4)(2) DNA complexes in the minor groove. The DNA binding properties of three polyamides, ImPyPyPy-beta-PyPyPyPy-beta-Dp, ImImPyPy-beta-PyPyPyPy-beta-Dp, and ImImImPy-beta-PyPyPyPy-beta-Dp, were analyzed by footprinting experiments on DNA fragments containing the respective match sites 5-AGTAATTTACT-3, 5-AGGTATTACCT-3 (Dp = dimethylaminopropylamide). Quantitative footprint titrations reveal that each polyamide binds its respective target site with subnanomolar affinity and 7-fold to over 30-fold specificity over double-base-pair mismatch sites. A 20-fold decrease in binding affinity is observed for placement of a side-by-side beta-beta ...
Gene expression is controlled by transcription factors that regulate the rates at which genes are expressed either by recruiting or inhibiting protein complexes that bind to the promoters or enhancers of target genes. Molecules that can specifically modulate these protein-DNA interfaces show promise as tools for understanding gene regulation pathways and may have application in human medicine. Hairpin pyrrole-imidazole polyamides are programmable oligomers that bind the DNA minor groove in a sequence-specific manner with affinities comparable to those of natural DNA-binding proteins. These cell-permeable small molecules have been shown to enter the nuclei of live cells, disrupt protein-DNA interactions, and downregulate endogenous gene expression. This thesis describes the use of polyamides to modulate gene expression in order to probe gene regulation mechanisms of several different biologically relevant systems. A polyamide is designed to target the glucocorticoid receptor transcription factor ...
This chapter describes three complementary footprinting methods and the protocols used for analysis of polyamide : DNA complexes: (1) MPE-Fe(II) footprinting, (2) affinity cleavage, and (3) quantitative DNase I footprint titration. Footprinting with methidiumpropyl-EDTA-Fe(II) [MPE-Fe(II)] is used to identify high-affinity polyamide-binding sites to near nucleotide resolution. Affinity cleavage is used to determine the orientation of the bound polyamide in the minor groove of DNA. Quantitative DNase I footprinting is used to determine equilibrium association constants (K_a) for polyamide-DNA complexes at previously identified match and mismatch sites. A pivotal step in the discovery-evaluation process of new polyamide motifs is the characterization of the affinity and specificity of next-generation molecules following the design-sythesis phase. In the design phase, it is often the case that the sequence preference, as well as the energetics of any new molecule binding at each potential site, is ...
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Polyamides containing N-methylimidazole and N-methylpyrrole amino acids are synthetic ligands that bind DNA by forming side-by-side complexes in the minor groove. Sequence-specificity depends on side-by-side aromatic amino acid pairings: imidazole (Im) opposite pyrrole (Py) targets a G•C base pair, Py/Im targets C•G and Py/Py targets T•A and A•T. This thesis describes work centered on the design of polyamide motifs that increase the binding site size limit, binding affinity and sequence repertoire of polyamides. In addition, polyamides were designed to bind within the regulatory regions of selected genes, which allowed investigations of polyamides as regulators of gene expression ...
Nylon fibers are protected from colorant staining by treating them with at least 2% we/wt (weight dry SAC/weight dry nylon fiber) of sulfonated aromatic aldehyde condensation product. The treated fibers are then fixed by the wet heat method.
DataMed is a prototype biomedical data search engine. Its goal is to discover data sets across data repositories or data aggregators. In the future it will allow searching outside these boundaries. DataMed supports the NIH-endorsed FAIR principles of Findability, Accessibility, Interoperability and Reusability of datasets with current functionality assisting in finding datasets and providing access information about them.
17. A method for improving the salt stress crack behavior of a polyamide composition, comprising (a) providing a polyamide composition comprising nylon-66, nylon-6/66 or nylon 66/6T, and optionally up to 40 weight %, based on the total polyamide component, of nylon-6, nylon-610, nylon-612, nylon-11, nylon-12 or mixtures thereof; (b) melt blending the polyamide with an ionomer comprising at least one copolymer comprising copolymerized units of ethylene, 3 to 20 weight % of copolymerized units of at least one α,β-unsaturated C3-C8 monocarboxylic acid and 0 to 30 weight % of copolymerized units of alkyl acrylate or alkyl methacrylate; and 30 to 90% of the total monocarboxylic acid functionalities are neutralized to salts with a mixture of zinc cations and sodium or lithium cations, wherein the salts comprise from 20 to 90% equivalents of zinc; to provide a molten blend composition comprising about 60 to about 80 weight % of the polyamide and about 20 to about 40 weight % of the ionomer; (c) ...
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There are a number of polyamides that have been employed as stationary phases in TLC, (e.g. polyamide 6,6 (Nylon 6,6) polyhexamethylenediamine, polyamide 6, (Nylon 6), aminopolycapro-lactame and polyamide 11 (Nylon 11) and polyaminoundecanoic acid. Polyamides can be produced. by polycondensing a dicarboxylic acid with a diamine and they can be represented by the following formula.. -[NH-(CH2)6-NH-CO-(CH2)x-C)]n. (if x = 4 then the product is Nylon 6,6, if x = 8 then the product is Nylon 6,10 etc.).. The polyamide material is interesting from a chromatographic point of view in that it can exhibit dispersive interactions with its aliphatic chains, polar characteristics due to interactions with the CO and the amino groups and even offer ion exchange capabilities if appropriately buffered. Nevertheless, the polar characteristics of the polyamides are the most commonly exploited and such materials have been used successfully for the separation of phenols, sulfonic acids, anilines, carbohydrates and a ...
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Oxygen barrier polyamide compositions exhibiting high oxygen scavenging capability suitable for extended shelf-life, packaging applications. Thus a polyamide composition comprises a polyamide homopolymer, copolymer, or blends thereof, and at least one polyamide reactive, oxidizable polydiene or oxidizable polyether. The polyamide products are particularly suited to making barrier packaging articles such as monolayer or multi-layer films, sheets, thermoformed containers and coinjection/coextrusion blow molded bottles comprising PET, polyolefin or polycarbonate as structural layers. Such articles are useful in a variety of oxygen-sensitive food, beverage, pharmaceutical and health care product packaging applications.
Title:Catalytic Synthesis of Bulk Hydrophilic Acetaldehyde-Modified Polyamide 46. VOLUME: 11 ISSUE: 2. Author(s):Hamidreza Barghi, Mikael Skrifvars and Mohammad J. Taherzadeh. Affiliation:School of Engineering, University of Borås, SE-50190 Boras, Sweden and Department of Chemical and Biological Engineering, Chalmers University of Technology, SE-41296 Gothenburg, Sweden.. Keywords:Hydroxylation, Lewis acid, nucleophilic substitute reaction, polyamides, synthesis.. Abstract:Hydrophilization of Polyamide 46 (PA46) via modification with acetaldehyde in continuous phase was studied. The chemical modification of PA 46 with acetaldehyde resulted in a water-swollen polymer with hydrophilic property. The polyamide 46 undergoes a nucleophilic addition with acetaldehyde in the presence of aluminum chloride as a catalyst. The extent of bulk hydroxyethylation using AlCl3 resulted in 95.65% modification counted as total N-hydroxyethylated polyamide 46. The modification resulted in improved hydrophilic ...
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PubMed Central Canada (PMC Canada) provides free access to a stable and permanent online digital archive of full-text, peer-reviewed health and life sciences research publications. It builds on PubMed Central (PMC), the U.S. National Institutes of Health (NIH) free digital archive of biomedical and life sciences journal literature and is a member of the broader PMC International (PMCI) network of e-repositories.
305346410 - EP 0972779 A2 2000-01-19 - Oligonucleotide-polyamide conjugates - Oligonucleotide-polyamide conjugates of the formula X-L-Y, where X is a polyamide, Y is an oligonucleotide, and L is a linker which forms a covalent bond with the amino-terminus of the polyamide X and the 3 phosphate group of the oligonucleotide Y. Conjugates may be synthesized by assembling a polyamide on a solid support matrix, adding a suitable linker molecule, followed by synthesis of the oligonucleotide. Methods for detecting specific polynucleotides with oligonucleotide-polyamide conjugates are also described. IMAGE [origin: WO8903849A1] Oligonucleotide-polyamide conjugates of the formula X-L-Y, where X is a polyamide, Y is an oligonucleotide, and L is a linker which forms a covalent bond with the amino-terminus of the polyamide X and the 3 phosphate group of the oligonucleotide Y. Conjugates may be synthesized by assembling a polyamide on a solid support matrix, adding a suitable linker molecule, followed by
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in which [0024]PA represents a polyamide block; [0025]PE represents a polyether block; and [0026]n represents the number of -PA-PE- units of the said copolymer,and in which [0027]the said blocks originate either entirely from polytrimethylene ether glycol (PO3G) or they originate from a blend or a copolymer of PO3G and of at least one from polyethylene ether glycol (PEG), polypropylene ether glycol (PPG), polytetramethylene ether glycol (PTMG), polyhexamethylene ether glycol and copolymers of tetrahydrofuran (THF) and of 3-alkyltetrahydrofuran (3MeTHF);as waterproof-breathable product or as additive conferring water-breathable properties on thermoplastic polymers in order to form a membrane for selective diffusion according to the nature of the gas;as additive in polyamide 6, polyamide 6.6 or copolyamide based on 6/6.6 intended to be converted to a film in order to improve the mechanical properties and/or the convertibility of the said polyamide ...
The polyester-grafted polyamide of the present invention comprises a polyamide as the backbone and a thermoplastic polyester as the graft and has a number-average molecular weight in terms of standard polymethyl methacrylate of 50,000 to 500,000 as determined by gel permeation chromatography using 1,1,1,3,3,3-hexafluoro-2-propanol. The polyester-grafted polyamide is useful as a modifier for polyesters and polyamides.
Linear polyamides are one of the more important classes of polymeric materials, with wide application in the fields of fibres and plastics. This review will be of interest to everyone who works with or studies polyamides. It is accompanied by around 400 abstracts compiled from the Polymer Library.
Linear polyamides are one of the more important classes of polymeric materials, with wide application in the fields of fibres and plastics. This review will be of interest to everyone who works with or studies polyamides. It is accompanied by around 400 abstracts compiled from the Polymer Library.
Polyamide Epoxy Definition - A polyamide epoxy is a polymer that employs a polyamide resin as a curing agent. A polyamide in an epoxy is essentially...
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Polyamides are a class of DNA minor groove binders that were developed from the natural product Distamycin A. PA25 (20-ring PA) showed better activity (3-fold) in the elimination of HPV16 episomes than PA1 (14-ring PA). Binding studies of PA1 and PA25 were performed in the long control region of HPV16 (7348-122 bp). PA1 showed similar binding affinity to perfect match and single mismatch binding sites. PA1 bound to double, triple, and quadruple mismatch sites with lower affinity. PA25 bound with similar binding affinity to perfect through triple mismatch binding sites. PA25 bound quadruple mismatch sites and nonspecifically. Therefore, it was concluded that PA25 is better at accommodating mismatches in its binding sites. The serine hydrolase family has a catalytic triad that consists of Serine, Histidine, and Glutamic/Aspartic Acid. Acetylcholinesterase (AChE) belongs to the serine hydrolase family. AChE hydrolyzes acetylcholine to stop signal transmission between neurons and thus is a drug target for
Polyamide is based on Nylon 6. Due to its activation process it exhibits a constant selectivity toward flavones, chalkones, anthraquinones, aromatic nitro compounds, DNP amino acids, phenols, carbonic acids, acid amides, sulphonic acids and amides of sulphonic acids as well as towards amines and quinones. Forces which contribute to the separation involve hydrogen bonding between the nitro groups, the phenolic protons, the carboxyl groups etc. of the sample and the free amino groups of the adsorbent.. Shop Polyamide Online. ...
As a commentator up-thread noted, any slip-and-slide model of sequence-specific DNA binding activity by transcription factors fails the sniff test: how is the activator (or repressor) able to effectively scan the nucleotide side-groups to achive site-specificity when the latter are coated with histones (in most eukaryotes) and with other attendant DNA-binding molecules (in all organisms). The notion that the chromosomal DNA molecule exists in all of its double-helical beauty for all proteins to probe seems rather tired and readily debunked to my mind. Ive been a hesitant skeptic of the histone code as anything other than correlative observations, but given the ubiquitous habit of histone compaction of large chromosomal segments, some portions of which obviously remain accessible to transcription factors, it seems clear to me that were missing some vital pieces of the puzzle.. Delete ...
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TY - JOUR. T1 - Towards high-performance materials based on carbohydrate-derived polyamide blends. AU - Wróblewska, Ola. AU - Leoné, Nils. AU - de Wildeman, Stefaan. AU - Bernaerts, Katrien. PY - 2019/3/4. Y1 - 2019/3/4. N2 - A bio-derived monomer called 2,3:4,5-di-O-isopropylidene-galactarate acid/ester (GalXMe) has great potential in polymer production. The unique properties of this molecule, such as its rigidity and bulkiness, contribute to the good thermal properties and appealing transparency of the material. The main problem, however, is that like other biobased materials, the polymers derived thereof are very brittle. In this study, we report on the melt blending of GalXMe polyamides (PAs) with different commercial PA grades using extrusion as well as blend characterization. Biobased PA blends showed limited to no miscibility with other polyamides. However, their incorporation resulted in strong materials with high Young moduli. The increase in modulus of the prepared GalXMe blends with ...
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This research project is directed towards establishing the relationship between the surface areas of intermediately sized molecules (50-300A{dollar}\sp2{dollar}) and their lateral diffusion coefficients in lipid bilayer membranes. Synthetic methods were developed to allow for the preparation of two series of macrocyclic polyamide amphiphiles, with and without fluorescent nitrobenzoxadiazole (NBD) labels, using macrocyclic polyamine aza-crown ethers as starting materials.;The geometry of the macrocyclic polyamides were determined using variable temperature NMR, which has indicated that both the C(O)-N bond and NBD-N bond in the smallest, labelled macrocyclic polyamide exhibit partial double bond character. As a consequence of this restricted bond rotation, both the amide groups and the NBD-N groups of macrocyclic polyamides can be considered as rigid planar moieties.;The surface areas occupied by the macrocyclic polyamides at the air-water interface were determined using a Langmuir film balance, and were
Cure characteristics and mechanical properties of short nylon fiber reinforced acrylonitrile butadiene rubber-reclaimed rubber composites were studied. Minimum torque, (maximum-minimum) torque and cure rate increased with fiber concentration. Scorch time and cure time decreased by the addition of fibers. Properties like tensile strength, tear strength, elongation at break, abrasion loss and heat build up were studied in both orientations of fibers. Tensile and tear properties were enhanced by the addition of fibers and were higher in the longitudinal direction. Heat build up increased with fiber concentration and were higher in the longitudinal direction. Abrasion resistance was improved in presence of short fibers and was higher in the longitudinal direction. Resilience increased on the introduction of fibers. Compression set was higher for blends ...
TY - JOUR. T1 - Separation of Lymphocyte-T and Lymphocyte-B by Nylon Fiber Columns. AU - Stewart, Keith Nicol. PY - 1981. Y1 - 1981. M3 - Comment/debate. VL - 38. SP - 123. EP - 125. JO - Medical Laboratory Sciences. JF - Medical Laboratory Sciences. SN - 0308-3616. IS - 2. ER - ...
Due to their inherent stability under ambient conditions, conductive polyheterocycles has become a topic of great research interest. Simultaneous chemical copolymerization and oxidation of pyrrole and N-methylpyrrole by bromine and iodine has been carried out. The composition of the copolymers can be effectively controlled by varying the monomer feed ratio. From elemental analysis the copolymer composition and the monomer reactivity ratios have been determined. As the copolymer composition changes, the IR absorption spectra show changes in the intensity of certain bands. In bromine-induced polymerization, the electrical conductivity, thermal stability, and bromine content of the copolymer complex decrease with increase in N-methylpyrrole fraction. X-ray photoelectron spectroscopy data suggest that a fixed fraction of bromine is incorporated as covalent bromide in the copolymer complex. When iodine is used, the halogen content do not show substantial differences among the copolymers but the ...
A unique hyperbranched polymeric system with a linear poly-2-dimethylaminoethyl methacrylate (pDMAEMA) block and a hyperbranched polyethylene glycol methyl ether methacrylate (PEGMEMA) and ethylene dimethacrylate (EGDMA) block was designed and synthesized via deactivation enhanced atom transfer radical polymerisation (DE-ATRP) for efficient gene delivery. Using this unique structure, with a linear pDMAEMA block, which efficiently binds to plasmid DNA (pDNA) and hyperbranched polyethylene glycol (PEG) based block as a protective shell, we were able to maintain high transfection levels without sacrificing cellular viability even at high doses. The transfection capability and cytotoxicity of the polymers over a range of pDNA concentration were analysed and the results were compared to commercially available transfection vectors such as polyethylene imine (branched PEI, 25 kDa), partially degraded poly(amido amine) dendrimer (dPAMAM; commercial name: SuperFect (R)) in fibroblasts and adipose tissue ...
To investigate the biochemical and cellular basis for the rise in polymorphonuclear leukocyte (PMN) count during epinephrine administration, PMN from subjects receiving epinephrine were studied for their capacity to adhere to nylon wool fibers and endothelial cell monolayers. After administration of epinephrine, the PMN count increased by 80% at 5 min, and isolated PMN adherence to nylon fibers fell from a base line of 44±2-18±3%. In contrast, when subjects were infused with the β-antagonist propanolol before receiving epinephrine, the PMN count failed to rise and PMN adherence was normal. Exposure of PMN endothelial cell monolayers to 0.1 μM epinephrine led to diminished PMN adherence that could be blocked by 10 μM propanolol but not by 10 μM phentolamine. Sera obtained from subjects 5 min after receiving epinephrine or from supernates derived from endothelial cell monolayers exposed to 90 nM epinephrine inhibited PMN adherence to nylon fibers. Addition of anticyclic AMP antisera but not ...
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3,271,237 PROCESS FOR THE PRODUCTION OF A FIBROUS POLYAMIDE LAMINAR STRUCTURE Erwin Summer and Klaus Gerlach, Obernau am Main, and Klaus Boehme, Erlenbach am Main, Germany, assignors to Vereinigte Glanzstofi-Fabriken AG., Wuppertal-Elberfeld, Germany No Drawing. Filed Sept. 15, 1964, Ser. No. 396,729 Claims priority, application Germany, Sept. 17, 1963, V 24,598 9 Claims. (Cl. 162-146) The invention relates to a process for the production of a fibrous polyamide laminar structure such as paper or non-woven textile fabrics, web-s, fleeces or sheets having a relatively smooth surface. The invention also relates to the products obtained by the process, including both paper and textile types of products. More particularly, the invention is concerned with the production of such non-woven fibrous products on a papermaking machine, wherein the fibers consist essentially of a polyamide. It is well known that synthetic fibers can be waterlaid form an aqueous dispersion onto a papermaking machine in order ...
TY - JOUR. T1 - Influence of calcium carbonate on polyamide 12 regarding melting, formability and crystallization properties. AU - Ippolito, Fabio. AU - Rentsch, Samuel. AU - Hübner, Gunter. AU - Claypole, Timothy. AU - Gane, Patrick. PY - 2019/5/1. Y1 - 2019/5/1. N2 - Controlling and adjusting the thermal properties of a compound to improve the additive manufacturing process of a polymer matrix through selective laser sintering is of key importance to achieve an optimized final part density as well as hardness. In the past, the purpose of adding mineral fillers to polymers was primarily one of cost reduction. Today, however, fillers are more often used to fulfil a functional role, such as improved thermal or mechanical properties of the polymer composite [1]. In this study, the influence of calcium carbonate as a mineral filler particle on the thermal properties in compression-molded polyamide 12 was investigated. The particle size distribution and the filler amount within the polyamide 12 ...
In a study in Occupational and Environmental Medicine, researchers found out that women during her mid 30s exposed to petrol products and synthetic fibers could treble the risk of developing breast
Mani brand 7-0 black mono, nylon sutures with both single and double arms. Trape spatula, Lancet, Cut Taper, and Reverse Cut needles ranging in length, curve, and diameter. Sold 12 per box.
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Amoeba (ARES) STRIKER AS03 Sniper Rifle (Urban Grey) 1/1 Scale High Performance Spring Powered Bolt Action Sniper Rifle Nylon Fiber Body & Handguard Nylon Fiber Pistol Grip (With Storage Compartment on grip) Metal Upper Receiver With Top Rail Metal Out
A carpet and upholstery protector that helps shield fibres from liquid stains. Spills will bead up upon contact with the surface allowing for fast damp sponge spill removal before they are absorbed. It is safe to use on nylon, wool, olefin, polyester, polyamide, poly-cotton and linen fibers. It is suitable to be mill applied to new carpet or fabric at ambient temperature. Alternatively, it can be applied to new carpet, rugs and upholstery (fabric rolls or furniture) as an aftermarket product. It can be applied via a simple hand pump or motorized flat jet sprayer to clean, wet or dry carpets.. A carpet and upholstery protector that helps shield fibres from liquid stains. Spills will bead up upon contact with the surface allowing for fast damp sponge spill removal before they are absorbed. It is safe to use on nylon, wool, olefin, polyester, polyamide, poly-cotton and linen fibres. It is suitable to be mill applied to new carpet or fabric at ambient temperature. Alternatively, it can be applied to ...
A set of aminoalkylamine substituted anthraquinones (AAQs) was successfully synthesised by aminating 1- or 1,5-chloroanthraquinones in a single reaction step. These substituted anthraquinones, 1C3 or 1,5C3, were tethered to minor groove binding polyamides with between 1 - 3 N-methyl pyrrole units (Py) to produce a library of Py-AAQ compounds. It was envisaged that these compounds could improve cytotoxicity through bimodal damage to DNA relative to the individual polyamide or AAQ moieties. A set of py-AAQ platinum complexes was also successfully synthesised by a platinum-mediated alkylamine to nitrile addition. The additional conjugation of a platinum nitrile complex to Py-AAQ conjugates was predicted to generate agents that are more cytotoxic than the Py-AAQ conjugates by damaging DNA via a minor groove binding (MGB)-intercalation-platination mechanism. All newly synthesised Py-AAQs and associated imino coordinated platinum(II) complexes were examined for cytotoxic activity in DLD-1 colon and ...
An improved composite polyamide membrane and methods of making the membrane are described. This improved membrane is prepared using a cationic polymeric wetting agent in an aqueous solution containing a polyfunctional amine reactant which is interfacially polymerized with an acyl halide to form a thin film polyamide discriminating layer on a microporous support. Alternatively, the wetting agent can be applied directly to the substrate and the interfacial polymerization can occur on said treated substrate. The resulting membrane exhibits an unexpected combination of high water flux, high rejection of divalent anion salts, variable sodium chloride rejection and good caustic resistance at low operating pressures. In one embodiment of this invention, a porous substrate is first treated with an aqueous piperazine solution containing a copolymer of vinylbenzyl dimethyl sulfonium chloride and methacrylic acid and then the coated microporous support is contacted with trimesoyl chloride in an organic
Add a touch of style and sophistication to your new season silhouettes with this shiny black silk mini skirt from Givenchys SS18 collection. Designed for a flattering high rise finish and detailed with a sultry scalloped lace hem; this fitted Givenchy skirt showcases the luxury French fashion houses unrivaled Italian craftsmanship. Size: 40. Gender: Female. Material: Silk/Cotton/Polyamide/Acetate.
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picture of crusher for hard resin like non reactive polyamide. This dictionary contains the following one hundred and- picture of crusher for hard resin like non reactive polyamide , he hi ho id if in is it kg km ko ky la lp ma me mi mo mr ms mu my na no nu ny od of hank hard hare hark harm harp hart hash hasp hast hate hath hats haul have lido lids lied lief lien lies lieu life lifo lift like ...
A method of bookbinding comprising the steps of a) applying a film comprising at least one hot melt polyamide at an application temperature of between about 175 C. and about 190 C. to the backbone of a book block said film having a tensile strength greater than about 400 psi and a Youngs modulus of less than about 12,000 psi and b) covering said book block having said film of polyamide with a book cover having a portion thereof in substantially parallel relation to said film.
Thank you for your interest in spreading the word about Biochemical Journal.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
Life-size, disarticulated full human skeleton consisting of 53 durable plastic pieces. One hand and foot are articulated on wire, while the other pair is loosely articulated on nylon filament. The vertebral column is also strung on nylon filament. Item #246777 skeleton comes with a black plastic sto...
In ,1993Feb26.124033.770 at otago.ac.nz, bioc07 at otago.ac.nz writes: , By an act of omission, an acrylamide gel containing DNA was , electroblotted before the DNA could be stained with EthBr. Is there an , easy way to stain the membrane after Southern blotting to get the , position of the markers and such. I suggest that EthBr staining (for locating MW markers) can be avoided totally by simply running end-labelled MW markers (Maniatis) which then produce bands directly on the autorad. We rountinely do this for all of our DNA blots. Bob Rutledge Petawawa National Forestry Institute brutledge at pnfi.forestry.ca ...
Transcription Factor-DNA Binding Motifs in Saccharomyces cerevisiae: Tools and Resources.s profile, publications, research topics, and co-authors
Revision date indicates the date the MSDS or SDS was last revised. MSDS / SDS are dated when they are originally issued AND when any significant change has been made to the chemical compound or research has revealed a health or physical hazard different from what was originally stated. Additional information regarding MSDS / SDS is available at https://www.osha.gov ...
R. Ukielski, M. Piątek: The effect of polyamide PA12 and polyester PBT blocks lengths on the structure and propertries of multiblock terpoly(amide-block-ester-block-amide) (TPAEA), Polimery, No 11-12/2007, 848. The ternary multiblock system terpoly(amide-b-ester-b-amide) (TPAEA) of the chemical structure: poly[(oligoamide-6.36)-block-(tetramethylene terephthalate)-block-laurolactam)]...
The use of heat treatment to improve solute rejection and fouling resistance of a polyamide reverse osmosis (RO) membrane was investigated in this study. Heat treatment was carried out by immersing the membrane samples in Milli-Q water at 70 °C for a specific duration. Heat treatment (24 h) reduced the pure water permeability from 4.1 to 2.8 L/m2hbar but improved conductivity rejection from 95.5 to 97.0%. As a result, a correlation was observed between changes in the two parameters. Marginal changes in the membrane surface characteristics (i.e. zeta potential, hydrophobicity, chemistry and roughness) were observed as a result of heat treatment. Heat treatment significantly improved the fouling resistance property of the RO membrane. When the secondary effluent was filtrated at an elevated permeated flux, the virgin RO membrane exhibited 30% flux decline while the heat-treated membrane showed only 12% flux decline. This is possibly because heat treatment resulted in a denser cross-linked active ...
Buy 119050020 - DURATOOL - Machine Screw, M5, Nylon 6.6 (Polyamide 6.6), 20 mm, Cheese Head Slotted at Farnell element14. order 119050020 now! great prices with fast delivery on DURATOOL products.
CWI Medical carries Fingertip Bandages such by Pro Advantage and Dynarex. Our fabric adhesive bandages are made with cotton and nylon fibers, allowing the fabric to move with the skin for less irritation and pull
A stain resistant composition for fibers having polyamide linkages prepared by polymerizing an α-substituted acrylic acid or ester in the presence of a sulfonated aromatic formaldehyde condensation plymer, or by polymerization of a sulfonated hydroxyaromatic ester of an α-substituted acrylic acid or acrylic acid, and methods for making and applying the composition.
Colouring of high molecular weight organic substances with the pigment colourant of formula (1) is carried out, for example, by mixing such a pigment colourant with the substrates using rolling mills, mixing or grinding apparatuses, as a result of which the pigment colourant is dissolved or finely divided in the high molecular weight material. The high molecular weight material with the admixed pigment colourant is subsequently processed by methods known perse, for example calendering, compression moulding, extrusion, coating, spinning, casting or by injection moulding, whereby the coloured material acquires its final form. The admixture of the pigment colourant may also be carried out immediately prior to the actual processing step, for example by continuously feeding a solid pigment colourant, for example a pulverulent pigment colourant, and, at the same time, a granulated or powdered high molecular weight organic material, and optionally also additional ingredients, for example additives, ...
Our highly breathable, comfortable, do-it-all merino wool T-shirt, the Tech Lite Short Sleeve Low Crewe PCT Sketchbook is a go-to top for four seasons worth of trails, travels and active pursuits. With capabilities as varied as the adventures youll take it on, the Tech Lite features a soft, open neck as well as our jersey corespun fabric - nylon fibers wrapped in merino wool to provide added strength and durability while maintaining next-to-skin softness. The contemporary graphic by Lindsey Fox is inspired by one the worlds great long trails.
Our highly breathable, comfortable, do-it-all merino wool T-shirt, the Tech Lite Short Sleeve Low Crewe Cadence Paths is a go-to top for four seasons worth of trails, travels and active pursuits. With capabilities as varied as the adventures youll take it on, the Tech Lite features a soft, open neck as well as our jersey corespun fabric - nylon fibers wrapped in merino wool to provide added strength and durability while maintaining next-to-skin softness. The contemporary graphic by Damon Watters gets you on the two-wheel wavelength.
A process for preparing a polyamide by reacting a mixture which comprises a monomer which has a nitrile group and has at least one other functional group capable of forming a carboxamide group, and comprises water, in the presence of titanium dioxide as catalyst, which comprises using titanium dioxide whose BET surface area, determined to the German standard DIN 66 131 volumetrically by the multipoint method, is in the range from 5 to 35 m2/g.
Patent No. U.S. 7,820,757 B2 BASF has been awarded a patent for a process for producing a polyamide with titanium dioxide pigments comprised of dispersing the titanium dioxide pigments in a mixture containing water and caprolac
This report studies sales (consumption) of Global Bio-Polyamide, Specialty Polyamide & Precursors Market, especially in United States, China, Europe and...
The Nylons are an a cappella group founded in 1978 in Toronto, Ontario, Canada, best known for their covers of pop songs such ... The Nylons appeared in Season 3 of the show on the "Treasure Island" episode, singing "The Lion Sleeps Tonight". These songs ... The Nylons original lineup consisted of Claude Morrison (tenor), Paul Cooper (baritone; born James Paul Cooper in Pikeville, ... In October 24, 1992, The Nylons sang "O Canada" at Atlanta-Fulton County Stadium in Atlanta, Georgia, preceding Game 6 of the ...
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Most of the readers here probably know that this is not the first time that plastic coolant fittings have failed in a spectacular fashion. In the early 2000s Ford settled a class action lawsuit brought by owners of various vehicles that had 4.6L V-8s with intake manifolds made of Nylon. These intake manifolds failed at the coolant passage. The intake manifold was replaced with a new design in which the coolant passage was made of… you guessed it, aluminum.. DuPont was at the forefront of the drive to use Nylon, specifically Glass Fiber reinforced Nylon 6/6 for engine parts starting with radiator end caps which were first adopted by Ford in 1986. Later, in 1996, the first intake manifolds manufactured from the same material started appearing on cars. Nylon intake manifolds have since become ubiquitous and I think that the technology is proven at this point. There are several advantages of using plastic in place of steel or aluminum for intake manifolds. The plastic intake manifolds are ...
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Real-time temperature dependence of X-ray diffraction patterns for nylons 65 and 56 was studied by synchrotron radiation to ... CitacióFranco, M. [et al.]. Synchrotron radiation studies on even-odd and odd-even nylons. "IOP Conference Series: Materials ... Significant differences were found between the temperature dependence of both nylons, although a transition towards a ... fiber diffraction patterns of this sheet structure were observed in several polyamides derived from odd units such as nylons 65 ...
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Synthetic polyamides, nylons, especially those having relatively simple repeating units, are generally hard to be decomposed ...
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  • However, typical fiber diffraction patterns of this sheet structure were observed in several polyamides derived from odd units such as nylons 65 and 56. (upc.edu)
  • Real-time temperature dependence of X-ray diffraction patterns for nylons 65 and 56 was studied by synchrotron radiation to gain understanding of the Brill transition usually occurring in polyamides. (upc.edu)
  • Synthetic polyamides, nylons, especially those having relatively simple repeating units, are generally hard to be decomposed under natural environmental conditions either through biological or through hydrolytic processes. (nii.ac.jp)
  • Although nylon polymers have found over the years significant commercial applications in fabrics and fibers, their application in electronic devices was hindered because it was impossible to create high quality thin films of ferroelectric nylons by solution processing. (mpg.de)
  • The scientists subjected the prototypes of the capacitors to extended stress cycles and demonstrated robustness of ferroelectric nylons under millions of operation cycles. (mpg.de)
  • Volume 4 on Nylons is a unique compilation and covers many of the recent technical research accomplishments in the area of engineering polymers, such as nitrogen containing main chain polymers (Nylons). (barnesandnoble.com)
  • This book summarizes many of the recent technical research accomplishments in the area of engineering polymers, such as oxygen containing main chain polymers (nylons). (wiley-vch.de)
  • Nylons, a family of synthetic polymers, were first introduced in the 1940s' for women's stockings and are nowadays among the most widely used synthetic fibers in textiles. (mpg.de)
  • The most important amide polymers are the nylons, an extremely versatile class of material that is an indispensable fibre and plastic . (britannica.com)
  • Wearing a pair of sheer nylons can't hurt anything, but if they are super conservative not wearing them could have them question if you're the right fit for the workplace environment. (weddingbee.com)
  • Them you need a pair of sheer champagne seamed nylons to finish your look. (whatkatiedid.com)
  • Watch full-lenght movie in HDV quality!Barbara looks like a doll in her electric blue satin gown, but soon this wicked prankster rides it up to show off the tops of her sheer gartered nylons and bare buttocks. (girlslovemature.com)
  • Our sheer compression socks blend in with any outfit, just like regular nylons. (spressowear.ca)
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  • Dead Stock 50's/60's Sheer Nylons. (ladolcevitaathens.com)
  • Label: Round The Clock - They Fit Dead Stock Sheer Nylons - Rhapsody Size: 9 - Trim Slim Condition: Unworn -See more Vintage Lingerie at: www.americanvintageclassics.com RWL305. (ladolcevitaathens.com)
  • EASY TO INSTALL : Since it's solar powered and requires no wiring, This sun visor have a vanity light , ✐ Material: Primary: Gold, Dead Stock 50's60's Sheer Nylons . (ladolcevitaathens.com)
  • To ensure authenticity of items being purchased, Dead Stock 50's60's Sheer Nylons . (ladolcevitaathens.com)
  • I think my sheer white panties are so cute and I know how much you like panties under my nylons. (sadiespanties.com)
  • poll: Should I wear nylons to a big interview? (weddingbee.com)
  • However, should I wear nylons? (weddingbee.com)
  • where I am from is pretty conservative and I dont think I have ever seen a woman wear nylons. (weddingbee.com)
  • I'd definitely wear nylons since I know a few people who work for hospitals and nylons are hospital policy. (weddingbee.com)
  • OK I'm going to wear nylons then! (weddingbee.com)
  • In fall and winter 2016, The Nylons toured and performed their farewell show throughout Canada. (wikipedia.org)
  • 2,5 kg Mega Sexy Nylons Rock'n'Roll Latex Fotografie vom Goliath. (burlesque-fashion.de)
  • Watch full-lenght movie in HDV quality!When it comes to sexy soft stockings no floozy in nylons looks better inthem than Stella here and that should make you pop a boner right away. (girlslovemature.com)
  • It you have a seepage pit for your septic system, you have to make sure that plastics and nylons do not make it in there or you will have issues to deal with that may be require costly replacements or repairs. (septictankcare.net)
  • As plastics the nylons still find employment as an engineering plastic-for example, in bearings, pulleys, gears, zippers, and automobile fan blades. (britannica.com)
  • The Nylons is the debut album from the Canadian a cappella quartet The Nylons released on Attic Records. (wikipedia.org)
  • Molybdenum disulphide-filled and oil-filled nylons have enhanced wear properties, while heat stabilized nylon will withstand higher operating temperatures. (skjdindia.com)
  • Nylons unterm rock pornokino in berlin, beliebte Suchen Sm Sex Sex Gratis Nylon. (buffaloqtl.org)
  • Nylon was first used commercially in a nylon- bristled toothbrush in 1938, [11] [12] followed more famously in women's stockings or "nylons" which were shown at the 1939 New York World's Fair and first sold commercially in 1940. (wikipedia.org)
  • Caro socks "Nylons", light blue/white/pink Smart stockings for riders made of high elastic material that adapts perfectly to the foot. (strato.de)
  • They may have revolutionized women's fashion, but do nylons really need to stick around for another 75 years? (dw.com)
  • For example, polyesters have oxygen atoms and nylons have nitrogen atoms in the backbone in addition to carbon atoms (Figure 4). (encyclopedia.com)
  • This final volume in the Handbook of Engineering and Speciality Thermoplastics covers Nylons and details the developments of the last decade with respect to their polymerization, properties, synthesis, and applications. (barnesandnoble.com)
  • Products using Shakespeare® Nylons exhibit excellent dimensional stability and thermal properties, suitable for either large or micro precision parts. (shakespearenylons.com)
  • Metalon MC is better impact strength and fatigue resistance compared with other cast nylons in the range. (metalonplastics.com)
  • well do what you love to do when you see a pair of panties under nylons. (sadiespanties.com)
  • Our injection molding grade nylons are suitable for large and micro precision parts, and are designed to offer exceptional dimensional stability, optimal viscosity and prime thermal properties. (shakespearenylons.com)
  • Watch her spread-eagling in her good nylons while drilling her insane little pooper! (girlslovemature.com)
  • There were less conservative firms but if you are right and this is a conservative area then I wouldn't risk it for the cost of a pair of nylons. (weddingbee.com)
  • The way this hottie models these silky stocking nylons is enough to make you want to jump in there and start wild hardcore fucking her until you break a sweat. (girlslovemature.com)
  • Having spent my early life in single sex boarding schools (I'm male), I had always fantasised about the tactile mystery of women in nylons, as well as the female anatomy in general. (experienceproject.com)
  • The hottest girls getting off in their nylons in front of your eyes. (nylonup.com)
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  • I've worked in Bay street (Canada's version of Wall Street) law firms and part of our dress code always included nylons with skirts. (weddingbee.com)
  • Significant differences were found between the temperature dependence of both nylons, although a transition towards a monoclinic structure characterized by a single equatorial reflection around 0.425-0.420 nm was observed to occur at high temperatures. (upc.edu)
  • The Nylons (1982) One Size Fits All (1982) - #59 AUS Seamless (1984) - #133 Billboard 200 Happy Together (1987) - #43 Billboard 200 Rockapella (1989) 4 on the Floor (1991, live) Live to Love (1992) The Best of the Nylons (1993) Illustrious (1993) Another Fine Mesh (1994) Harmony: The Christmas Songs (1994) Because. (wikipedia.org)
  • In October 24, 1992, The Nylons sang "O Canada" at Atlanta-Fulton County Stadium in Atlanta, Georgia, preceding Game 6 of the 1992 World Series, in which their hometown team, the Toronto Blue Jays, won their first championship. (wikipedia.org)
  • On May 30, 2014, the Nylons performed a show in Toronto which included the participation of every living past or present member of the band. (wikipedia.org)