Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).Spinal Cord: A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.Paraplegia: Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.Quadriplegia: Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts.Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.Recovery of Function: A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.Spinal Cord Compression: Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence.Cervical Vertebrae: The first seven VERTEBRAE of the SPINAL COLUMN, which correspond to the VERTEBRAE of the NECK.Nerve Regeneration: Renewal or physiological repair of damaged nerve tissue.Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.Autonomic Dysreflexia: A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a STROKE. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20(3):355-60)Spinal Cord Neoplasms: Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.Spinal Cord Regeneration: Repair of the damaged neuron function after SPINAL CORD INJURY or SPINAL CORD DISEASES.Urinary Bladder, Neurogenic: Dysfunction of the URINARY BLADDER due to disease of the central or peripheral nervous system pathways involved in the control of URINATION. This is often associated with SPINAL CORD DISEASES, but may also be caused by BRAIN DISEASES or PERIPHERAL NERVE DISEASES.Spinal Cord Ischemia: Reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with ARTERIOSCLEROSIS, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to INFARCTION of spinal cord tissue.Thoracic Vertebrae: A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)Wheelchairs: Chairs mounted on wheels and designed to be propelled by the occupant.Locomotion: Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.Injections, Spinal: Introduction of therapeutic agents into the spinal region using a needle and syringe.Contusions: Injuries resulting in hemorrhage, usually manifested in the skin.Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Spinal Injuries: Injuries involving the vertebral column.Electric Stimulation Therapy: Application of electric current in treatment without the generation of perceptible heat. It includes electric stimulation of nerves or muscles, passage of current into the body, or use of interrupted current of low intensity to raise the threshold of the skin to pain.Motor Neurons: Neurons which activate MUSCLE CELLS.Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Axons: Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body.Injury Severity Score: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.Pressure Ulcer: An ulceration caused by prolonged pressure on the SKIN and TISSUES when one stays in one position for a long period of time, such as lying in bed. The bony areas of the body are the most frequently affected sites which become ischemic (ISCHEMIA) under sustained and constant pressure.Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)Myelitis: Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.Laminectomy: A surgical procedure that entails removing all (laminectomy) or part (laminotomy) of selected vertebral lamina to relieve pressure on the SPINAL CORD and/or SPINAL NERVE ROOTS. Vertebral lamina is the thin flattened posterior wall of vertebral arch that forms the vertebral foramen through which pass the spinal cord and nerve roots.Spinal Nerve Roots: Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Athletic Injuries: Injuries incurred during participation in competitive or non-competitive sports.Motor Activity: The physical activity of a human or an animal as a behavioral phenomenon.Spinal Nerves: The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The spinal nerve plexuses and the spinal roots are also included.Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.Electromyography: Recording of the changes in electric potential of muscle by means of surface or needle electrodes.Pyramidal Tracts: Fibers that arise from cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord. Many authorities say the pyramidal tracts include both the corticospinal and corticobulbar tracts.Cordotomy: Any operation on the spinal cord. (Stedman, 26th ed)Chondroitin ABC Lyase: An enzyme that catalyzes the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups. (Enzyme Nomenclature, 1992)Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.Reperfusion Injury: Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.Lumbosacral Region: Region of the back including the LUMBAR VERTEBRAE, SACRUM, and nearby structures.Reflex: An involuntary movement or exercise of function in a part, excited in response to a stimulus applied to the periphery and transmitted to the brain or spinal cord.Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.Urinary Catheterization: Passage of a CATHETER into the URINARY BLADDER or kidney.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Posterior Horn Cells: Neurons in the SPINAL CORD DORSAL HORN whose cell bodies and processes are confined entirely to the CENTRAL NERVOUS SYSTEM. They receive collateral or direct terminations of dorsal root fibers. They send their axons either directly to ANTERIOR HORN CELLS or to the WHITE MATTER ascending and descending longitudinal fibers.Anterior Horn Cells: MOTOR NEURONS in the anterior (ventral) horn of the SPINAL CORD which project to SKELETAL MUSCLES.Neck Injuries: General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck.Hindlimb: Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)Gait Disorders, Neurologic: Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.Ganglia, Spinal: Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.Spinal Canal: The cavity within the SPINAL COLUMN through which the SPINAL CORD passes.Myelin Sheath: The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.Neuronal Plasticity: The capacity of the NERVOUS SYSTEM to change its reactivity as the result of successive activations.Spinal NeoplasmsOligodendroglia: A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.Evoked Potentials, Somatosensory: The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.Anesthesia, Spinal: Procedure in which an anesthetic is injected directly into the spinal cord.Neuroprotective Agents: Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Respiratory Paralysis: Complete or severe weakness of the muscles of respiration. This condition may be associated with MOTOR NEURON DISEASES; PERIPHERAL NERVE DISEASES; NEUROMUSCULAR JUNCTION DISEASES; SPINAL CORD DISEASES; injury to the PHRENIC NERVE; and other disorders.Hyperalgesia: An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.Neuroglia: The non-neuronal cells of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, participate in the BLOOD-BRAIN BARRIER and BLOOD-RETINAL BARRIER, form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.Spinal DiseasesAstrocytes: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.Glial Fibrillary Acidic Protein: An intermediate filament protein found only in glial cells or cells of glial origin. MW 51,000.Walking: An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.Urinary Bladder: A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.Pain Measurement: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.Neurologic Examination: Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.Umbilical Cord: The flexible rope-like structure that connects a developing FETUS to the PLACENTA in mammals. The cord contains blood vessels which carry oxygen and nutrients from the mother to the fetus and waste products away from the fetus.Myelography: X-ray visualization of the spinal cord following injection of contrast medium into the spinal arachnoid space.Analysis of Variance: A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.Spinal Fusion: Operative immobilization or ankylosis of two or more vertebrae by fusion of the vertebral bodies with a short bone graft or often with diskectomy or laminectomy. (From Blauvelt & Nelson, A Manual of Orthopaedic Terminology, 5th ed, p236; Dorland, 28th ed)Rehabilitation Centers: Facilities which provide programs for rehabilitating the mentally or physically disabled individuals.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Muscle, Skeletal: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.Spinal Stenosis: Narrowing of the spinal canal.Ossification, Heterotopic: The development of bony substance in normally soft structures.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Physical Stimulation: Act of eliciting a response from a person or organism through physical contact.Gliosis: The production of a dense fibrous network of neuroglia; includes astrocytosis, which is a proliferation of astrocytes in the area of a degenerative lesion.Urodynamics: The mechanical laws of fluid dynamics as they apply to urine transport.Magnetic Resonance Imaging: Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.Afferent Pathways: Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.Sensation: The process in which specialized SENSORY RECEPTOR CELLS transduce peripheral stimuli (physical or chemical) into NERVE IMPULSES which are then transmitted to the various sensory centers in the CENTRAL NERVOUS SYSTEM.Trauma Severity Indices: Systems for assessing, classifying, and coding injuries. These systems are used in medical records, surveillance systems, and state and national registries to aid in the collection and reporting of trauma.Reflex, Abnormal: An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes.Microglia: The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.Forelimb: A front limb of a quadruped. (The Random House College Dictionary, 1980)Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)Hematoma, Epidural, Spinal: A rare epidural hematoma in the spinal epidural space, usually due to a vascular malformation (CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS) or TRAUMA. Spontaneous spinal epidural hematoma is a neurologic emergency due to a rapidly evolving compressive MYELOPATHY.Epidural Space: Space between the dura mater and the walls of the vertebral canal.H-Reflex: A monosynaptic reflex elicited by stimulating a nerve, particularly the tibial nerve, with an electric shock.Efferent Pathways: Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. Such impulses are conducted via efferent neurons (NEURONS, EFFERENT), such as MOTOR NEURONS, autonomic neurons, and hypophyseal neurons.Leg Injuries: General or unspecified injuries involving the leg.Spinal Cord Stimulation: Application of electric current to the spine for treatment of a variety of conditions involving innervation from the spinal cord.Urethra: A tube that transports URINE from the URINARY BLADDER to the outside of the body in both the sexes. It also has a reproductive function in the male by providing a passage for SPERM.Accidents, Traffic: Accidents on streets, roads, and highways involving drivers, passengers, pedestrians, or vehicles. Traffic accidents refer to AUTOMOBILES (passenger cars, buses, and trucks), BICYCLING, and MOTORCYCLES but not OFF-ROAD MOTOR VEHICLES; RAILROADS nor snowmobiles.Lumbar Vertebrae: VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.Mice, Inbred C57BLUrination: Discharge of URINE, liquid waste processed by the KIDNEY, from the body.Spine: The spinal or vertebral column.Lung Injury: Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES.Disability Evaluation: Determination of the degree of a physical, mental, or emotional handicap. The diagnosis is applied to legal qualification for benefits and income under disability insurance and to eligibility for Social Security and workmen's compensation benefits.Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.Behavior, Animal: The observable response an animal makes to any situation.Evoked Potentials, Motor: The electrical response evoked in a muscle or motor nerve by electrical or magnetic stimulation. Common methods of stimulation are by transcranial electrical and TRANSCRANIAL MAGNETIC STIMULATION. It is often used for monitoring during neurosurgery.Exercise Therapy: A regimen or plan of physical activities designed and prescribed for specific therapeutic goals. Its purpose is to restore normal musculoskeletal function or to reduce pain caused by diseases or injuries.Activities of Daily Living: The performance of the basic activities of self care, such as dressing, ambulation, or eating.Phrenic Nerve: The motor nerve of the diaphragm. The phrenic nerve fibers originate in the cervical spinal column (mostly C4) and travel through the cervical plexus to the diaphragm.Neurons, Afferent: Neurons which conduct NERVE IMPULSES to the CENTRAL NERVOUS SYSTEM.Myelin Proteins: MYELIN-specific proteins that play a structural or regulatory role in the genesis and maintenance of the lamellar MYELIN SHEATH structure.Ejaculation: The emission of SEMEN to the exterior, resulting from the contraction of muscles surrounding the male internal urogenital ducts.Syringomyelia: Longitudinal cavities in the spinal cord, most often in the cervical region, which may extend for multiple spinal levels. The cavities are lined by dense, gliogenous tissue and may be associated with SPINAL CORD NEOPLASMS; spinal cord traumatic injuries; and vascular malformations. Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile sense preserved (sensory dissociation). Lower extremity spasticity and incontinence may also develop. (From Adams et al., Principles of Neurology, 6th ed, p1269)Physical Therapy Modalities: Therapeutic modalities frequently used in PHYSICAL THERAPY SPECIALTY by PHYSICAL THERAPISTS or physiotherapists to promote, maintain, or restore the physical and physiological well-being of an individual.Movement: The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.Muscle Relaxants, Central: A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)Wounds, Stab: Penetrating wounds caused by a pointed object.Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Tibial Nerve: The medial terminal branch of the sciatic nerve. The tibial nerve fibers originate in lumbar and sacral spinal segments (L4 to S2). They supply motor and sensory innervation to parts of the calf and foot.Nerve Fibers, Myelinated: A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.Orthotic Devices: Apparatus used to support, align, prevent, or correct deformities or to improve the function of movable parts of the body.Decompression, Surgical: A surgical operation for the relief of pressure in a body compartment or on a body part. (From Dorland, 28th ed)Gait: Manner or style of walking.Nociceptors: Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.Peripheral Nerves: The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.Posture: The position or attitude of the body.Biomechanical Phenomena: The properties, processes, and behavior of biological systems under the action of mechanical forces.Cats: The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)Pain Threshold: Amount of stimulation required before the sensation of pain is experienced.Ergometry: Any method of measuring the amount of work done by an organism, usually during PHYSICAL EXERTION. Ergometry also includes measures of power. Some instruments used in these determinations include the hand crank and the bicycle ergometer.Weight-Bearing: The physical state of supporting an applied load. This often refers to the weight-bearing bones or joints that support the body's weight, especially those in the spine, hip, knee, and foot.Central Nervous System: The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.Sacrum: Five fused VERTEBRAE forming a triangle-shaped structure at the back of the PELVIS. It articulates superiorly with the LUMBAR VERTEBRAE, inferiorly with the COCCYX, and anteriorly with the ILIUM of the PELVIS. The sacrum strengthens and stabilizes the PELVIS.Eye Injuries: Damage or trauma inflicted to the eye by external means. The concept includes both surface injuries and intraocular injuries.Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)Robotics: The application of electronic, computerized control systems to mechanical devices designed to perform human functions. Formerly restricted to industry, but nowadays applied to artificial organs controlled by bionic (bioelectronic) devices, like automated insulin pumps and other prostheses.Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Cell Transplantation: Transference of cells within an individual, between individuals of the same species, or between individuals of different species.Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.Stem Cell Transplantation: The transfer of STEM CELLS from one individual to another within the same species (TRANSPLANTATION, HOMOLOGOUS) or between species (XENOTRANSPLANTATION), or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). The source and location of the stem cells determines their potency or pluripotency to differentiate into various cell types.Thoracic Injuries: General or unspecified injuries to the chest area.Urinary Bladder Diseases: Pathological processes of the URINARY BLADDER.Sciatic Nerve: A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.Spinal Fractures: Broken bones in the vertebral column.Electrodes, Implanted: Surgically placed electric conductors through which ELECTRIC STIMULATION is delivered to or electrical activity is recorded from a specific point inside the body.Functional Laterality: Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot.Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).Wallerian Degeneration: Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.Interneurons: Most generally any NEURONS which are not motor or sensory. Interneurons may also refer to neurons whose AXONS remain within a particular brain region in contrast to projection neurons, which have axons projecting to other brain regions.Nerve Tissue ProteinsVeterans: Former members of the armed services.Craniocerebral Trauma: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.Ependyma: A thin membrane that lines the CEREBRAL VENTRICLES and the central canal of the SPINAL CORD.Leg: The inferior part of the lower extremity between the KNEE and the ANKLE.Neural Stem Cells: Self-renewing cells that generate the main phenotypes of the nervous system in both the embryo and adult. Neural stem cells are precursors to both NEURONS and NEUROGLIA.Neural Conduction: The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.Neural Pathways: Neural tracts connecting one part of the nervous system with another.Animals, Newborn: Refers to animals in the period of time just after birth.Ischium: One of three bones that make up the coxal bone of the pelvic girdle. In tetrapods, it is the part of the pelvis that projects backward on the ventral side, and in primates, it bears the weight of the sitting animal.Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.Methylprednisolone Hemisuccinate: A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.Analgesics: Compounds capable of relieving pain without the loss of CONSCIOUSNESS.Abdominal Injuries: General or unspecified injuries involving organs in the abdominal cavity.Neural Prostheses: Medical devices which substitute for a nervous system function by electrically stimulating the nerves directly and monitoring the response to the electrical stimulation.Wounds, Nonpenetrating: Injuries caused by impact with a blunt object where there is no penetration of the skin.AccidentsStilbamidines: STILBENES with AMIDINES attached.DislocationsBrain: The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.Hyperesthesia: Increased sensitivity to cutaneous stimulation due to a diminished threshold or an increased response to stimuli.Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.Cauda Equina: The lower part of the SPINAL CORD consisting of the lumbar, sacral, and coccygeal nerve roots.Cell Count: The number of CELLS of a specific kind, usually measured per unit volume or area of sample.Evoked Potentials: Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.Man-Machine Systems: A system in which the functions of the man and the machine are interrelated and necessary for the operation of the system.Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Arm Injuries: General or unspecified injuries involving the arm.Neurotrophin 3: A neurotrophic factor involved in regulating the survival of visceral and proprioceptive sensory neurons. It is closely homologous to nerve growth factor beta and BRAIN-DERIVED NEUROTROPHIC FACTOR.GAP-43 Protein: A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.Rats, Long-Evans: An outbred strain of rats developed in 1915 by crossing several Wistar Institute white females with a wild gray male. Inbred strains have been derived from this original outbred strain, including Long-Evans cinnamon rats (RATS, INBRED LEC) and Otsuka-Long-Evans-Tokushima Fatty rats (RATS, INBRED OLETF), which are models for Wilson's disease and non-insulin dependent diabetes mellitus, respectively.Schwann Cells: Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons.Nerve Fibers: Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.Hand Injuries: General or unspecified injuries to the hand.Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Urinary Bladder Calculi: Stones in the URINARY BLADDER; also known as vesical calculi, bladder stones, or cystoliths.
... caused by the organism Treponema pallidum Spinal cord injury Myelomeningocele Syringomyelia Intra-articular steroid injections ... Loss of peripheral sensation and proprioception leads to repetitive microtrauma to the joint in question; this damage goes ... Patients with neurosyphilis tend to have knee involvement, and patients with syringomyelia of the spinal cord may demonstrate ...
Krembil Research Institute
... spinal cord injuries, cerebral ischemia (stroke), vascular brain malformations, aneurysms, brain tumours and pain disorders. ... Krembil scientists are at work on a diverse array of human healthcare questions within multiple research programs. At the ... spinal cord injuries, neurophthalmologic and other ocular disorders, multiple sclerosis and autoimmune disorders. The ... A. Lozano & S. Kennedy, 2003) Neural adult stem cell transplantation findings show promising results in repairing spinal cord ...
... spinal cord injury, sports injuries, or stroke. A Cochrane review published in 2016 has raised questions about the ethical ... There is some evidence that HBOT is effective for late radiation tissue injury of bone and soft tissues of the head and neck. ... The larger units may be rated for lower pressures if they are not primarily intended for treatment of diving injuries. A rigid ... Some people with radiation injuries of the head, neck or bowel show an improvement in quality of life. Importantly, no such ...
Mobility assistance dog
Hox genes in amphibians and reptiles
... it may be possible to heal injuries of the spinal cord or brain, repair damaged organs and reduce scarring and fibrosis after ... This raises a question as to why humans which also possess an analog to these genes cannot regrow and regenerate limbs. Beside ... Some amphibians and reptiles have the ability to regenerate limbs, eyes, spinal cords, hearts, intestines, and upper and lower ... The cells at the site of the injury have the ability to undifferentiate, reproduce rapidly, and differentiate again to create a ...
Sexuality after spinal cord injury
People with SCI who wish to be parents may question their ability to raise children and opt not to have them, but studies have ... ISBN 978-1-60406-727-9. Field-Fote, E. (26 March 2009). "Spinal cord injury: An overview". In Field-Fote, E. Spinal Cord Injury ... University of Alabama at Birmingham Spinal Cord Injury Model System video series Sexuality and spinal cord injury: Where we are ... ISBN 1-4557-2807-1. Elliott, S. (26 March 2009). "Sexuality after spinal cord injury". In Field-Fote, E. Spinal Cord Injury ...
Degrees of freedom problem
... additional DOFs allow patients with brain or spinal cord injury to often retain movement while relying on a reduced set of ... Finally, the very nature of the DOF problem poses questions. For example, does the nervous system really have difficulty in ... In the latter 19th and early 20th centuries, many scientists believed that all motor control came from the spinal cord, as ... Hart, C.B. (2010). "A Neural Basis for Motor Primitives in the Spinal Cord". Journal of Neuroscience. 30 (4): 1322-1336. doi: ...
... sustained life-threatening injuries after the 200 km per hour impact. Bailey's spinal cord was severed, causing instant ... The most telling question and answer in the inquest was when the driver was asked; 'You would not want to be driving while you ... Jet later died at Brisbane's Mater Children's Hospital on the night of 28 February due to massive internal injuries after life ...
... spinal cord injury, or peripheral neuropathy. Upper-limb orthoses Clavicular and shoulder orthoses Arm orthoses Functional arm ... a material of choice for construction necessitated the idea of creating a plaster of Paris mould of the body part in question. ... or have experienced a spinal cord injury or stroke. Equally, orthoses are sometimes used prophylactically or to optimise ... Spinal orthoses may also be used in the treatment of spinal fractures. A Jewett brace, for instance, may be used to facilitate ...
However, the human trial was not initiated until October 13, 2010 in Atlanta for spinal cord injury research. On November 14, ... There are thus questions about the "completeness" of reprogramming and the somatic memory of induced pluripotent stem cells. ... Osteoarthritis Stroke and traumatic brain injury repair Learning disability due to congenital disorder Spinal cord injury ... "Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A ...
Research is underway to potentially use stem cell therapy to treat heart disease, diabetes, and spinal cord injuries. ... While many of these views are religious in origin, the questions raised by cloning are faced by secular perspectives as well. ... "Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice". Proc. Natl. Acad. Sci. U.S.A ... showing the potential for regenerative medicine in brain and neural injuries. In bioethics, the ethics of cloning refers to a ...
Better Half (House)
Park suggests the woman has a spinal cord injury which blocks the sensation from her genitals. Adams thinks it might be ... Foreman starts to question the Alzheimer's diagnosis and reminds House that the symptoms only started after he was admitted. ... He asks about her eye injury from Andres' attack. She asks Joseph to leave and when he does (after kissing her goodbye), she ... He tells her that she has to sit, focus, and answer their questions. House and Foreman realize that Andres is probably confused ...
"Difficulty in brainstem death testing in the presence of high spinal cord injury". British Journal of Anaesthesia. 92 (5): 760- ... "Frequently Asked Questions About Donation". DNR will be honored. You can still be a tissue donor.. ... these cells come from the spinal cord. Sometimes these body movements can cause false hope for family members. ... raising questions of legal death. This gained greater urgency with the widespread use of life support equipment, as well as ...
Kathryn Holloway (volleyball)
It can be used by an athlete with a spinal cord injury to increase their blood pressure and is performed by causing a painful ... of the examination shall inform the Technical Delegate to withdraw the athlete from the particular competition in question. Any ... "Boosting in Athletes with High Level Spinal Cord Injury: Incidence, Knowledge and Attitudes of Athletes in Paralympic Sport" ( ... but many competitors with spinal injuries are still thought to be using it as a performance enhancer. Athletes with spinal ...
Erythropoietin in neuroprotection
These results suggested that RhEpo has both an acute and delayed beneficial action in ischemic spinal cord injury. In contrast ... However it has been questioned whether EpoR may or may not be a determining factor for the nervous system function. The ... The reported presence of Epo within the spinal fluid of infants and the expression of Epo-R in the spinal cord, suggested a ... Epo has a favorable response in brain and spinal cord injuries like mechanical trauma or subarachnoid hemorrhages. Research ...
... the laminectomy is performed below the termination of the spinal cord (conus), potentially reducing the risk of injury. ... or not to undergo such post-rhizotomy orthopaedic surgery depends on the circumstances of the rhizotomy recipient in question. ... to expose the spinal cord and spinal nerves underneath. Ultrasound and an x-ray locate the tip of the spinal cord, where there ... is a term referring to a neurosurgical procedure that selectively destroys problematic nerve roots in the spinal cord. This ...
... such as spinal cord injury. If polydendrocytes were capable of giving rise to myelinating oligodendrocytes, one would expect ... Another unanswered question is whether the polydendrocyte pool eventually becomes depleted after they are used to generate ... In the embryonic spinal cord, a major source of polydendrocytes is the ventral ventricular zone of the pMN domain marked by the ... "Gliogenesis in rat spinal cord: Evidence for origin of astrocytes and oligodendrocytes from radial precursors". Journal of ...
It was later reported that Sorensen had suffered a C-1 vertebrae fracture with spinal cord edema. Sorensen's doctors estimated ... On March 18, 2013, Jesse was on the TNA YouTube show The List, hosted by Robbie E & So Cal Val speaking of return questions and ... Sorensen made an appearance on July 8 at Destination X, addressing his neck injury and saying he hoped Zema Ion would win the ... he suffered a severe neck injury that took him out of action for over a year. Throughout 2008, Sorensen competed in various ...
Leahy War Victims Fund
Priestley received injuries in a race-car accident Quoted in Cnn.com article on actor Christopher Reeve's spinal cord injury ... More recently, questions about ethics of surgeon investigators in the Pro Disc study have been raised, specifically in a New ... He has been consulted numerous times regarding the spinal injuries of such high-profile celebrities as Christopher Reeve and ... He served as President of the American Spinal Injury Association from 2003 to 2005. Zigler's role as Principal Investigator for ...
... fractures in delicate areas such as the spinal cord, massive confusion, in-cohesive, unable to answer simple questions, ... They have minor injuries; first aid and home care are sufficient, a doctor's care is not required. Injuries are along the lines ... The Injury Severity Score (ISS) is another example of a trauma scoring system. This assigns a score from 0 to 75 based on ... Some crippling injuries, even if not life-threatening, may be elevated in priority based on the available capabilities. During ...
Steven Fletcher (politician)
The Jungle (The Killing)
He also notes vaginal bruising, a broken finger, and a spinal cord nicked by a serrated edge. Holder asks if he left a 'Calling ... She avoids the question. The dead girl is identified as Ashley Kwon, and Holder meets with her parents to tell them she is dead ... He announces the cause of death multiple sharp force injuries across the neck region. ...
... in the pain signaling pathways of the spinal cord and brain. In the case of traumatic brain injury, the injection of a NAAG ... Coyle, J.T. (1997). "The nagging question of the function of N-acetylaspartylglutamate". Neurobiology of Disease. 4 (3-4): 231- ... Future research focuses on the role of NAAG in pain perception, brain injury, and schizophrenia while developing NAAG peptidase ... Stimulation of the mGluR3 by NAAG has been, however, questioned, finding relevant glutamate contamination in commercially ...
Urinary tract infection
Persons with spinal cord injury are at increased risk for urinary tract infection in part because of chronic use of catheter, ... Holt, JD; Garrett, WA; McCurry, TK; Teichman, JM (15 February 2016). "Common Questions About Chronic Prostatitis". American ... Eves, FJ; Rivera, N (April 2010). "Prevention of urinary tract infections in persons with spinal cord injury in home health ... those with spinal cord injuries, and those who have urinary catheters. Pregnancy is an exception and it is recommended ...
A main focus of neuroscience is the biology and physiology of the human brain and spinal cord. Some related clinical ... Review of systems (ROS) or systems inquiry: a set of additional questions to ask, which may be missed on HPI: a general enquiry ... Physical medicine and rehabilitation (or physiatry) is concerned with functional improvement after injury, illness, or ... Neurological (consciousness, awareness, brain, vision, cranial nerves, spinal cord and peripheral nerves) ...
Amyotrophic lateral sclerosis
A few people with ALS have symptoms that are limited to one spinal cord region for at least 12 to 24 months before spreading to ... Head injury. A 2015 review found that moderate to severe traumatic brain injury is a risk factor for ALS, but whether ... is a 12-item questionnaire that replaces the single question about breathing with a question each about dyspnea, orthopnea, and ... Typical or "classical" ALS involves neurons in the brain (upper motor neurons) and in the spinal cord (lower motor neurons).[27 ...
... for example when the tumor is wrapped around a vulnerable structure such as the spinal cord or a major organ or blood vessel.[ ... "What Questions Should I Ask My Doctor?: Questions to ask after treatment ends". Rtanswers.com. 2010-09-22. Archived from the ... In the CNS for example, cranial nerve injury typically presents as a visual acuity loss 1-14 years post treatment. In the ... When Dupuytren's disease is at the nodules and cords stage or fingers are at a minimal deformation stage of less than 10 ...
Spinal cord injury. These conditions can impair coughing, swallowing, clearing the airways, and in the worst cases, breathing. ... Questions & Answers: Flu Shot Archived 1 October 2015 at the Wayback Machine CDC publication updated 24 July 2006. Retrieved 19 ... Centers for Disease Control and Prevention: "QUESTIONS & ANSWERS: Novel H1N1 Flu (Swine Flu) and You" Archived 4 March 2010 at ...
Posttraumatic stress disorder
Head injury. *Spinal cord injury. Demographic. *Geriatric trauma. *Pediatric trauma. Complications. *Posttraumatic stress ... The success of exposure-based therapies has raised the question of whether exposure is a necessary ingredient in the treatment ... doi:10.1016/j.injury.2012.02.015. PMID 22409991.. *^ Kassam-Adams N, Marsac ML, Hildenbrand A, Winston F (December 2013). " ... "The Operational Stress Injury Social Support (OSISS) Program for Canadian Veterans". Archived from the original on 6 July 2011. ...
سرطان پروستات - ویکیپدیا، دانشنامهٔ آزاد
Spinal cord compression can occur with metastases to the spine and can be treated with steroids, surgery, or radiation therapy ... "WHO Disease and injury country estimates". World Health Organization. 2009. Archived from the original on 2009-11-11. Retrieved ... Most of those who are newly diagnosed and made a treatment choice can not correctly answer over half of the questions. ... Prostate cancer in the spine can also compress the spinal cord, causing tingling, leg weakness and urinary and fecal ...
Acute lymphoblastic leukemia
Cancer spreading into the Central nervous system (brain or spinal cord) has worse outcomes. ... This result is questioned as no causal mechanism linking electromagnetic radiation with cancer is known. ... "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015 ... also known as a spinal tap) can determine whether the spinal column and brain have been invaded. Brain and spinal column ...
Serotonin-norepinephrine reuptake inhibitor
... projections from the medial and dorsal raphe and the descending projections from the caudal raphe into the spinal cord. ... Dosages fluctuate depending on the SNRI used due to varying potencies of the drug in question as well as multiple strengths for ... The implication behind these findings suggests use of SNRIs as potential anti-inflammatories following brain injury or any ...
This is the only cervical spinal cord disease seen in horses less than 1 month of age, and a radiograph can diagnose the ... "Frequently Asked Questions:"What types of classes are seen at Arabian horse shows?". Arabian Horse Association. Archived from ... and often are misdiagnosed as suffering from a head injury caused by an accident. Severity varies, with some foals having fast ... "Frequently Asked Questions: Military/Government". The Papers of George Washington. University of Virginia. Archived from the ...
Spinal cord. *Myelitis: Poliomyelitis. *Demyelinating disease *Transverse myelitis. *Tropical spastic paraparesis. *Epidural ... Exposure to pesticides and a history of head injury have each been linked with Parkinson disease (PD), but the risks are modest ... Palliative care team members can help answer questions and guide people with Parkinson's on these complex and emotional topics ... GBD 2015 Disease Injury Incidence Prevalence Collaborators (October 2016). "Global, regional, and national incidence, ...
Taylor, RG; Gleave, JRW (1957). "Incomplete Spinal Cord Injuries". Bone & Joint Journal. 39-B (3): 438-450. doi:10.1302/0301- ... the question of whether the pressure waves satisfy the definition of "shock wave" is unimportant, and one can consider the ... This is consistent with other work showing remote spinal cord injuries from ballistic impacts. ... that a focusing effect from concave surfaces can concentrate the pressure wave on the spinal cord producing significant injury. ...
"Difficulty in brainstem death testing in the presence of high spinal cord injury". British Journal of Anaesthesia. 92 (5): 762 ... "Frequently Asked Questions About Donation". DNR will be honored. You can still be a tissue donor.. ... these cells come from the spinal cord. Sometimes these body movements can cause false hope for family members. ... raising questions of legal death. This gained greater urgency with the widespread use of life support equipment, as well as ...
Then the brain's connection to the cranial nerves and spinal cord are severed, and the brain is lifted out of the skull for ... Making a decision as to what order the organs are to be removed will depend highly on the case in question. Organs can be ... mode and manner of death or to evaluate any disease or injury that may be present for research or educational purposes. (The ... Forensic science involves the application of the sciences to answer questions of interest to the legal system. ...
There is also FacingDisability for Families Facing Spinal Cord Injuries , which has a peer counseling program in addition to ... "Questions & Answers on Sponsorship", Alcoholics Anonymous World Services, Inc. 2005, p. 7. ... 1,000 videos drawn from interviews of people with spinal cord injuries, their families, caregivers and experts. ... The Operational Stress Injury Social Support (OSISS) Program for Canadian Veterans. Archived 2011-07-06 at the Wayback Machine ...
Other neurological disorder: damage to cervical and lumbosacral spinal cord, motor/sensory deficits, absent deep tendon ... "Varicella Treatment Questions & Answers". CDC Guidelines. CDC. Archived from the original on 17 July 2007. Retrieved 23 August ... keeping the fingernails short to decrease injury from scratching, and the use of paracetamol (acetaminophen) to help with ... and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic ...
Assisted death in the United States
National Spinal Cord Injury Association. *World Association of Persons with Disabilities. *American Association of People with ... Public support for assisted death ranges from around 45% to 75% depending on how in-depth the questions are and how they are ... In 1991, a ballot question asked if terminally ill adults should be allowed to receive physician assisted death.The initiative ...
Multiple system atrophy
Spinal cord. *Myelitis: Poliomyelitis. *Demyelinating disease *Transverse myelitis. *Tropical spastic paraparesis. *Epidural ... One particularly serious problem, the drop in blood pressure upon standing up (with risk of fainting and thus injury from ... The region in question includes the SHC2 gene which, in mice and rats, appears to have some function in the nervous system. The ... Palsy of the vocal cords is an important and sometimes initial clinical manifestation of the disorder. ...
Functional magnetic resonance imaging
This is a type of specialized brain and body scan used to map neural activity in the brain or spinal cord of humans or other ... It never stops functioning and firing neuronal signals, as well as using oxygen as long as the person in question is alive. In ... Clinicians also use fMRI to anatomically map the brain and detect the effects of tumors, stroke, head and brain injury, or ... Lastly, there is an ethical question relating to fMRI scanning. This testing of BOLD has led to controversy over if fMRIs are ...
"Mechanism of Injury for Pulmonary Over-Inflation Syndrome". DAN Medical Frequently Asked Questions. Diver's Alert Network. ... Foley catheterization may be necessary for spinal cord AGE if the person is unable to urinate. ... Lung injuries can also occur during rapid decompression, although the risk of injury is lower than with explosive decompression ... lung over-pressure injury (LOP) and burst lung. Consequent injuries may include arterial gas embolism, pneumothorax, ...
Oliver Sacks has reported the case of a young woman who lost her proprioception due to a viral infection of her spinal cord.[31 ... This is because this discovery questions a long-lasting a priori that we have on plants. In some cases this has led to a shift ... particularly as physical therapy for ankle or knee injuries. Slacklining is another method to increase proprioception. ... even at the spinal cord level), as ankle sprain events occur in perhaps 100 ms or less. In accordance, a model has been ...
جراحی مغز و اعصاب - ویکیپدیا، دانشنامهٔ آزاد
Traumatic injuries of peripheral nerves. *Tumors of the spine, spinal cord and peripheral nerves ... http://www.aans.org/medical_students/questions.asp *↑ "The society of British neurological surgeons". Retrieved 11/03/2011. ... Some indications for spine surgery include spinal cord compression resulting from trauma, arthritis of the spinal discs, or ... Al-Zahrawi performed surgical treatments of head injuries, skull fractures, spinal injuries, hydrocephalus, subdural effusions ...
Chronic fatigue syndrome
Spinal cord. *Myelitis: Poliomyelitis. *Demyelinating disease *Transverse myelitis. *Tropical spastic paraparesis. *Epidural ... "PM & R : the journal of injury, function, and rehabilitation. 2 (5): 338-346. doi:10.1016/j.pmrj.2010.04.008. PMC 2933136 . ... "News & Events - Drug Development for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome (ME and CFS): Questions and Answers ...
Soon after describing Stegosaurus, Marsh noted a large canal in the hip region of the spinal cord, which could have ... This study showed that 9.8% of Stegosaurus specimens examined had injuries to their tail spikes. Additional support for this ... The thermoregulation hypothesis has been seriously questioned, since other stegosaurs such as Kentrosaurus, had more low ... Buchholz (née Giffin) EB (1990). "Gross Spinal Anatomy and Limb Use in Living and Fossil Reptiles". Paleobiology. 16 (4): 448- ...
They are attached at the back (side nearest the spinal cord) to the arytenoids cartilages, and at the front (side under the ... When vocal injury is done, often an ENT specialist may be able to help, but the best treatment is the prevention of injuries ... although in strictly scientific usage acoustic authorities would question most of them. The main point to be drawn from these ... Vocal cord nodules and polypsEdit. Vocal nodules are caused over time by repeated abuse of the vocal cords which results in ...
... post-spinal cord injury spasticity, spasms of the head and neck, eyelid, vagina, limbs, jaw, and vocal cords.[ ... "Ten Common Questions (and Their Answers) About Off-label Drug Use". Mayo Clinic Proceedings. 87 (10): 982-990. doi:10.1016/j. ... "Efficacy and Safety of Botulinum Toxin Type A in Spasticity Caused by Spinal Cord Injury: A Randomized, Controlled Trial". ... Other tests, such as brain scan and spinal fluid examination, may help to rule out other causes. If the symptoms of botulism ...
Wikipedia:WikiProject Medicine/Cochrane/Cochrane Review List/Musculoskeletal, Oral, Skin and Sensory
Positioning and spinal bracing for pain relief in metastatic spinal cord compression in adults PMID 26400848 https://doi.org/ ... Repositioning for pressure injury prevention in adults PMID 24700291 https://doi.org/10.1002/14651858.CD009958.pub2 ... Questions. Cochrane Musculoskeletal, Oral, Skin and Sensory Network: Reviews to be considered for Wikipedia ... Interventions for the treatment of metastatic extradural spinal cord compression in adults PMID 26337716 https://doi.org/ ...
spinal cord anterior/posterior patterning. • cell development. • negative regulation of cell differentiation. • positive ... Age-reversal effects of 'young blood' molecule GDF-11 called into question, retrieved 20 May 2015. ... "GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice" ... spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos". Developmental Biology. 208 (1): 222-32. doi:10.1006 ...
... spinal cord injury, or peripheral neuropathy. Types of upper-limb orthoses. *Upper-limb orthoses *Clavicular and shoulder ... a material of choice for construction necessitated the idea of creating a plaster of Paris mould of the body part in question. ... or have experienced a spinal cord injury or stroke. Equally, orthoses are sometimes used prophylactically or to optimise ... Spinal orthoses may also be used in the treatment of spinal fractures. A Jewett brace, for instance, may be used to facilitate ...
Update on the pathophysiology and management of syringomyelia unrelated to Chiari malformation | Neurología (English Edition)
el Masry and Biyani6 and Curati et al.7 suggest that complete spinal cord lesions (grade A on the American Spinal Injury ... fluid-filled cyst within the spinal cord. Although this is the most widely accepted definition, some authors question its ... Spinal cord injury is the cause most frequently addressed in the literature, with syringomyelia developing in 0.5%-4.5% of ... Presence of complete spinal cord injury is probably the most significant risk factor. ...
Factsheet #1: Common Questions about Spinal Cord Injury
Common Questions about Spinal Cord Injury. 1. What is Spinal Cord Injury?. Spinal Cord Injury (SCI) is damage to the spinal ... not sustain a spinal cord injury if only the bones around the spinal cord (the vertebrae) are damaged, but the spinal cord is ... Spinal Cord Injury Resource Center (NSCIRC) provides information and referral on many subjects related to spinal cord injury. ... 2. What is the spinal cord and the vertebra?. The spinal cord is the major bundle of nerves that carry nerve impulses to and ...
UAB - Spinal Cord Injury Model System - Question
Question about spinal cord injuries from IED - (#38738) - Community Advice
My characters injury is going to be a spinal cord injury. Ive been trying to do research online about spinal cord injuries ... My first question is it possible to have a temporary spinal cord injury from an IED instead of a permanent injury? If its a ... Question about spinal cord injuries from IED. Started by valerielynn82 on 04/14/2011 4:29pm ... temporary spinal cord injury would the person automatically regain feeling in their extremities or would they regain feeling ...
Adult (Fetal) Stem Cell Trial for Spinal Cord Injury Presents New Ethical Questions | National Review
Adult (Fetal) Stem Cell Trial for Spinal Cord Injury Presents New Ethical Questions By Wesley J. Smith * About Wesley J. Smith ... Adult (Fetal) Stem Cell Trial for Spinal Cord Injury Presents New Ethical Questions. * ... "This IND is a significant step forward for our spinal cord injury program," said Stephen Huhn, MD, FACS, FAAP, Vice President, ... sites for its Phase I/II clinical trial for chronic spinal cord injury, which is currently underway in Switzerland and Canada. ...
Common Questions on Spinal Cord Injuries - Burke Rehabilitation Hospital
What is Spinal Cord Injury?. After a spinal cord injury, a persons sensory, motor, and reflex messages are affected. Severe ... Spinal Cord Injury (SCI), although not the most common injury in the United States, has a significant impact on the lives of ... What is the Spinal Cord?. The spinal cord provides the communication between the brain and the muscles and organs of the body, ... We recognize September as Spinal Cord Injury Awareness Month. Whether youre dealing with an injury, supporting a family member ...
Common Spinal Cord Injury Questions Answered
... can be described as injury or damage to the patients spinal cord of a person resulting in the loss of functions like ... Spinal Injuries Simply put Spinal Cord Injury (SCI) can be described as injury or damage to the patients spinal cord of a ... Is spinal cord injury curable?. No. As of today, there is no known cure for spinal cord injury. Research is still on to find ... Do people with spinal cord injury ever improve?. Due to the swelling of the patients spinal cord at the site of the injury, ...
The CatWalk Spinal Cord Injury Research Trust - Questions - Givealittle
The CatWalk Trust is committed to a world where spinal cord injury does not mean paralysis for life. - Givealittle is the place ... The CatWalk Spinal Cord Injury Research Trust. Please resolve the following errors. ... Frequent questions General help Tips for success Report a page Contact Givealittle ...
Ten frequently asked questions concerning cure of spinal cord injury
Please ask and comment... 1. Will there be a cure for spinal cord injury? • The answer to this question of course depend on ... If a cure means eradication of spinal cord injury, I think that it is unlikely in my lifetime. If a cure means complete ... Let me try to recap some of these questions to stimulate discussion. ... restoration of all function to normal or pre-injury levels for all people with ...
Frequently Asked Questions - Center for Spinal Cord Injury | Kennedy Krieger Institute
Home Patient Care Centers & Programs Center for Spinal Cord Injury Frequently Asked Questions ... Talk to your friends and family about the importance of spinal cord injury and paralysis research. Most people are unaware of ... The International Center for Spinal Cord Injury team is not only conducting our own clinical research, we are actively engaging ... At the International Center for Spinal Cord Injury (ICSCI), we are constantly assessing our therapeutic interventions ...
CAM LLP | 5 Common Questions about Spinal Cord Injury (SCI) Treatments
We have put together a list of answers to common questions that those with a spinal cord injury may have on their road to ... What is Spinal Cord Injury?. A spinal cord injury can be defined or described as damage to any part of the spinal cord or ... What are the treatment stages of Spinal Cord Injury?. There are three primary treatment stages of spinal cord injury: ... What are the treatments for Spinal Cord Injury?. The treatments involved with spinal cord injuries are sometimes different ...
Common Questions about Spinal Cord Injury | Answers | Spinal Cord Injury Zone!
Spinal Cord Injury (SCI) is damage to the spinal cord that results in a loss of function such as mobility or feeling. ... The mission of The Spinal Cord Injury Zone is to archive important Spinal Cord Injury News and Spinal Cord Injury Information ... 1. What is Spinal Cord Injury?. Spinal Cord Injury (SCI) is damage to the spinal cord that results in a loss of function such ... Spinal Cord Injury Zone / Answers / 2005 / May / 2nd Common Questions about Spinal Cord Injury. Published: May 2, 2005 , Source ...
Answers to Questions on Exercise & Nutrition after SCI | Answers | Spinal Cord Injury Zone!
The mission of The Spinal Cord Injury Zone is to archive important Spinal Cord Injury News and Spinal Cord Injury Information ... The Spinal Cord Injury Zone is 100% not-for-profit, all proceeds are donated to spinal cord injury related charities. ... The Spinal Cord Injury Zone website is a not-for-profit Spinal Cord Injury educational Knowledge Base. ... Sign up to receive updates on new spinal cord related articles and find out whats new on the Spinal Cord Injury Zone! ...
Autonomic Dysreflexia in Spinal Cord Injury: Overview, Pathophysiology, Causes of Autonomic Dysreflexia
All caregivers, practitioners, and therapists who interact with individuals with spinal cord injuries must be aware of this ... Autonomic dysreflexia is a potentially dangerous clinical syndrome that develops in individuals with spinal cord injury, ... Need a Curbside Consult? Share cases and questions with Physicians on Medscape consult. Share a Case ... encoded search term (Autonomic Dysreflexia in Spinal Cord Injury) and Autonomic Dysreflexia in Spinal Cord Injury What to Read ...
Geron Corp. Begins First Embryonic Stem Cell Treatment on Patient for Spinal Cord Injuries - ABC News
has started the first embryonic stem-cell treatment on a patient with spinal cord injuries. It is the first time this treatment ... If the stem cell therapy, which in this case is for the treatment of spinal cord injuries, is deemed safe, it will be seen as a ... The researchers involved with the trial hope that they will travel to the site of a recent spinal cord injury and release ... "There is great hope that these revolutionary treatments will be effective, not only in spinal cord injury but also in other ...
Frequently Asked Questions About Spinal Cord Injuries
Our Houston spine injury lawyers answer some of the most frequently asked questions on our blog. ... Plenty of individuals have questions regarding spine injuries. ... What Causes a Spinal Cord Injury?. Spinal cord injuries are ... a spinal cord injury.. What Can a Spinal Cord Injury Do to the Body?. A serious spinal cord injury can result in paralysis. ... What Is the Cost of Living with a Spinal Cord Injury?. Living with a spinal cord injury can result in millions of dollars ...
Frequently Asked Questions about Spinal Cord Injuries
... the average family cant cover the costs associated with a spinal cord injury, which can run more than $1 million the first ... Why are spinal cord injuries so serious?. A spinal cord injury includes damage to any part of the spinal cord or the nerves ... How do most spinal cord injuries occur?. Motor vehicle accidents are one of the most common sources of spinal cord injuries. ... How does paralysis relate to a spinal cord injury?. The higher on the spinal cord an injury occurs, the more extensive the ...
Answers - The Most Trusted Place for Answering Life's Questions
In Spinal Cord Spinal cord injuries can result in? Depending on the type of spinal cord injury, the result can be a total loss ... In Spinal Cord Treatment for spinal cord injury? There are various treatments available for spinal chord injury. Ifyou feel ... Incomplete spinal cord injury? An incomplete spinal cord injury happens when only part of the spinal cord is damaged. This will ... In Spinal Cord What is the prognosis for spinal cord injuries? prognosis.depends on the location and extent of injury. Injuries ...
Spinal Cord Injury - Practice Questions
Spinal Cord Injury. Practice Questions. Click on the Practice Question to view the synthesis of the literature and the practice ... Q: In individuals with spinal cord injuries, does the presence of a pressure injury alter calorie and protein requirements? ... Q: What metabolic changes occur (i.e. energy expenditure, nitrogen balance) after spinal cord injury (SCI)? Is there a ... Q: Do individuals with spinal cord injuries (SCI) have an increased prevalence of cardiovascular disease (CVD)/cardiometabolic ...
Spinal Cord Injury, Questions | EM Lyceum
... traumatic spinal cord injury? 2. How do you treat neurogenic shock? 3. What is your management and disposition for elderly ... I think the most important questions for EPs include what the incidence is of Cervicoligamentous injury or spinal cord injury ... Spinal Cord Injury, Questions. Posted on March 4, 2015 by emlyceum 1. What imaging do you use for patients with possible acute ... what is the risk of clinically important spinal cord injury or Cervicoligamentous injury in a patient with a negative CT after ...
Frequently Asked Questions - Spinal Cord Injury Lawyer
Catastrophic injuries like spinal cord injuries (SCI) and traumatic brain injuries (TBI) are often worth significantly more ... the more severe the injury, the more money the case is worth. For example, successful spinal cord injury lawsuits typically ... How much does a personal injury lawyer cost? Often, personal injury lawyers do not take money upfront. Personal injury lawyers ... Can I file a personal injury lawsuit without a lawyer? Yes, you can file a personal injury lawsuit without a lawyer. However, ...
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... or from spinal cord injury survivors who go to other doctors or... ... Big Questions. You cant undo your spinal cord injury, but taking these steps will help minimize your risk for bladder cancer. ... Consortium for Spinal Cord Medicine. (2006). Bladder management for adults with spinal cord injury: A clinical practice ... Bladder Cancer After Spinal Cord Injury. Bladder Cancer. You may have heard it from physicians, from family members who have ...
Spinal Cord Injury Attorney on Frequently Asked Questions
Spinal cord injury attorney answers common questions about spine injuries and provides information about injury compensation. ... What are the medical costs associated with spinal cord injuries?. How severe are spinal cord injuries?. Spinal cord injuries ... How to Contact a Spinal Cord Injury Lawyer Near Me. If you have a question about spinal cord injuries that we did not answer ... Frequently Asked Questions about Spinal Cord Injuries. *How severe are spinal cord injuries? ...
Teenager's miraculous recovery from traumatic brain injuries - Brain and Spinal Cord
Frequently Asked Questions. Car Crash Traumatic Brain Injury Yes, a car crash can cause a traumatic brain injury (TBI) in many ... Brain and Spinal Cord Injury Rehabilitation puts most families in crushing debt. Often, a lawsuit is the only way to finance it ... Spinal Cord Injury *Spinal Cord Injury Treatment ». *Spinal Cord Injury Prognosis ». *Spinal Cord Levels » ... TBI Traumatic Brain Injury A traumatic brain injury (TBI) occurs when there is a "bump, blow, or jolt to the head" that causes ...
How Can A Brain And Spinal Cord Injury Lawyer Help Me? | Brain Injury | Brain & Spinal Cord Injury Information
Your lawyer will represent your interests and fight to hold the at-fault party liable for your injuries. The law firm may be ... A brain and spinal cord injury attorney can help you protect your rights and pursue a fair payout following an accident. ... Home » Frequently Asked Questions » How Can a Brain and Spinal Cord Injury Lawyer Help Me? ... Your Brain & Spinal Cord Injury Lawyer Will Protect Your Rights. Like many personal injury cases, brain and spinal cord injury ...
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What is the role of CT scanning in the workup of spinal cord injury (SCI)?
Need a Curbside Consult? Share cases and questions with Physicians on Medscape consult. Share a Case ... The epidemiology of spinal cord injury. Stover SL, DeLisa JA, Whiteneck GG, eds. Spinal Cord Injury. Gaithersburg, Md: Aspen; ... National Spinal Cord Injury Statistical Center (NSCIS). Spinal cord injury facts and figures at a glance. February 2011. [Full ... Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. ...
What are the categories of the American Spinal Injury Association (ASIA) Impairment Scale of spinal cord injury (SCI)?
The extent of injury is defined by the American Spinal Injury Association (ASIA) Impairment Scale (modified from the Frankel ... The epidemiology of spinal cord injury. Stover SL, DeLisa JA, Whiteneck GG, eds. Spinal Cord Injury. Gaithersburg, Md: Aspen; ... National Spinal Cord Injury Statistical Center (NSCIS). Spinal cord injury facts and figures at a glance. February 2011. [Full ... Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. ...
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... frequently asked questions about spinal cord injuries in Virginia. ... The experienced attorneys at Cooper Hurley Injury Lawyers answer clients ... Questions About Spinal Cord Injury. What are the symptoms of a spinal cord injury?. Depending on the part of your spine that ... How is a spinal cord injury treated?. There is no cure for spinal cord injuries. Treatment is available that can help reduce ...
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Damage to the spinal cord9
- Spinal Cord Injury (SCI) is damage to the spinal cord that results in a loss of function such as mobility or feeling. (makoa.org)
- It is when doctors make every effort to reduce/prevent shock, maintain the ability for the patient to breathe while immobilizing the neck to prevent any further damage to the spinal cord, and prevent the risk of ulcers, blood clots, bladder issues and more. (camllp.com)
- Paraplegia , on the other hand, is the result of damage to the spinal cord below the cervical area but above the waist (also known as the thoracic region). (hauptman-obrien.net)
- According to the National Institute of Neurological Disorders and Stroke, damage to the spinal cord can be complete or incomplete. (defranciscolaw.com)
- Spinal cord injury is damage to the spinal cord that causes loss of sensation (feeling) and motor (muscular) control. (faqs.org)
- A Spinal Cord Injury (SCI) causes damage to the spinal cord, resulting in a loss of mobility or feeling. (gorenlaw.com)
- Spinal cord injury is a broad term for damage to the spinal cord. (coloplast.co.uk)
- Possibly even simple therapies such as exercise or just breathing will play a role in preventing long-term hypoxia and damage to the spinal cord. (eurekalert.org)
- Spinal cord injury (SCI) is caused by direct mechanical damage to the spinal cord that usually results in complete or incomplete loss of neural functions such as mobility and sensory function [ 8 ]. (hindawi.com)
Cervical spinal cord i3
- A 36 year old motorcyclist sustained an isolated cervical spinal cord injury at C5/6 level discovered on MRI after falling off his motorcycle in a road traffic collision. (bestbets.org)
- Selection of 34 patients from 114 patients with cervical spinal cord injury, who sustained hyperextension spinal cord injury with no bone damage and no previous history of vertebral or cord disease were selected. (bestbets.org)
- A non-surgical model of cervical spinal cord injury induced with focused ultrasound and microbubbles. (fusfoundation.org)
- Sygen is an experimental drug that is being given to reducing the loss of function.There is spine specialist in NJ that has experience with spinal cord injuries. (tripr.tv)
- Medications such as sedatives and sometimes special bracing equipment are used to stop the patient from moving in order to decrease inflammation of cells and site of injury, as well as align the spine to avoid any possible complications. (camllp.com)
- For the best interests of the person who has been injured, a personal injury lawyer should be contacted shortly after the doctor has determined that the spine has in fact been seriously injured. (camllp.com)
- The CDC says that alcohol plays a role in 25 percent of spine injuries. (dudeklawfirm.com)
- Cervical spine injury is highly dependent on the mechanism of injury following blunt and penetrating assault. (medscape.com)
- Depending on the part of your spine that has been damaged, spinal cord injury may have several symptoms. (cooperhurley.com)
- Injuries to your cervical spine may result in quadriplegia or paraplegia . (cooperhurley.com)
- For example, people with a T4 injury (damage to vertebrae in the thoracic segment of the spine) may be unable to control their bladder and may struggle with breathing problems. (defranciscolaw.com)
- However, studies show that more women have experienced spine injuries in recent years and victims have included more older people injured in falls. (klinespecter.com)
- The spinal cord is protected by the bones of the spine and is cushioned by a clear fluid called cerebral spinal fluid. (coloplast.co.uk)
- Rehabilitation nurse (retired-challenged) helps rebuild shattered lives from traumatic brain and spine injuries, illnesses (physical and mental), diseases, pain, catastrophic and other injuries. (braininjuryselfrehabilitation.com)
- A spinal Cord Injury is an amazingly genuine kind of injury when spine that breaks or separates vertebrae. (authorstream.com)
- Currently, stem cell treatments for spine problems, specifically for spinal cord injury, are in the early stages. (spinerf.org)
- The primary options for treatment of spinal cord injury include structural stabilization of the bones of the spine, but little therapy for the damaged cord itself is currently available. (fusfoundation.org)
- The incidence of spinal cord injuries peaks among people in their early 20s, with a small increase in the elderly population due to falls and degenerative diseases of the spine. (healthofchildren.com)
- The most common injury level for the five to 13 age group is the high cervical spine (C1-C4). (healthofchildren.com)
- The level of injury is very helpful in predicting what parts of the body might be affected by paralysis and loss of function. (makoa.org)
- Talk to your friends and family about the importance of spinal cord injury and paralysis research. (kennedykrieger.org)
- A serious spinal cord injury can result in paralysis. (fibichlaw.com)
- Paralysis can be either total or partial, and can be categorized as paraplegia or quadriplegia depending on the location and severity of the injury. (fibichlaw.com)
- With total paralysis, the victim loses control over both sides of the body below the point of the injury. (fibichlaw.com)
- How does paralysis relate to a spinal cord injury? (hauptman-obrien.net)
- A severe spinal cord injury can result in paralysis. (hauptman-obrien.net)
- For example, an injury high on the spinal cord (the so-called cervical region) can result in quadriplegia , or paralysis from the neck down, including the arms, torso and legs. (hauptman-obrien.net)
- Injuries lower on the spinal canal typically result in less paralysis or loss of motor ability and/or sensation throughout the body and extremities. (hauptman-obrien.net)
- Injuries higher on the spinal canal typically result on more extensive paralysis. (hauptman-obrien.net)
- As such, someone with an incomplete injury may not suffer from paralysis. (defranciscolaw.com)
- More than 11,000 people suffer a spinal cord injury each year in the United States, with many experiencing severe chronic pain, paralysis and death. (klinespecter.com)
- Injury to the spinal cord, which consists of a bundle of nerves that runs from the base of the brain and down the back, can result in loss of sensation and movement, including paralysis of all four limbs, or quadriplegia , and paralysis of the lower half of the body, paraplegia . (klinespecter.com)
- A missed spinal fracture can result in permanent paralysis. (1stclaims.co.uk)
- Spinal cord injuries can lead to paralysis. (1stclaims.co.uk)
- Paralysis is a life changing injury to suffer. (1stclaims.co.uk)
- When you make a paralysis compensation claim, your lawyer will have to show the court that your injuries have occurred as a direct result of the negligence of a third party. (1stclaims.co.uk)
- If you are successful in your paralysis compensation claim you will receive an amount of monetary compensation which will be calculated by taking into account the extent of your injuries - both physical and psychological and by taking into account any financial losses which you have incurred as a direct result of your injuries. (1stclaims.co.uk)
- The amount which is awarded to the winning party in paralysis compensation cases is likely to be large as it will assess effects of your injury such as inability to work, loss of earnings, adaptations to your home and so on, over an extended period of time. (1stclaims.co.uk)
- The study also shows that the elderly are most often victims of these spinal cord injuries whose symptoms range from temporary numbness to paralysis. (prweb.com)
- Severe injury to the spinal cord causes paralysis and complete loss of sensation to the parts of the body controlled by the spinal cord segments below the point of injury. (healthofchildren.com)
- Spinal cord injury is not always obvious: numbness or paralysis may result immediately after SCI or later on as swelling gradually occurs in or around the spinal cord. (healthofchildren.com)
- Yes, a car crash can cause a traumatic brain injury (TBI) in many ways. (brainandspinalcord.org)
- A traumatic brain injury (TBI) occurs when there is a "bump, blow, or jolt to the head" that causes issues with the functions of the. (brainandspinalcord.org)
- Can a Fall Cause Traumatic Brain Injury? (brainandspinalcord.org)
- A typology of alcohol use patterns among persons with recent traumatic brain injury or spinal cord injury: implications for treatment matching. (medscape.com)
- Also, recent research suggests that in the case of traumatic brain injury, axons can continue to degenerate even years after injury and may play a role in the development of Alzheimer's disease-like changes in the brain. (medicalnewstoday.com)
- Every year in the United States, there are more than 1.5 million cases of traumatic brain injury, at an annual healthcare cost of over $60 billion. (medicalnewstoday.com)
- What is an Acute Spinal Cord Injury? (answers.com)
- Blood pressure management after acute spinal cord injury. (medscape.com)
- Furlan JC, Fehlings MG. Cardiovascular complications after acute spinal cord injury: pathophysiology, diagnosis, and management. (medscape.com)
- Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers. (sigmaaldrich.com)
- Administration of methylprednisolone (MP) for the treatment of acute spinal cord injury (SCI) is not recommended. (medscape.com)
- The first Phase I trial, sponsored by GERON Corporation, began in 2009 and involved the transplantation of embryonic-derived stem cells into patients with acute spinal cord injury. (spinerf.org)
- Noninvasive, targeted gene therapy for acute spinal cord injury using LIFU-mediated BDNF-loaded cationic nanobubble destruction. (fusfoundation.org)
International Center for Spinal Cord I2
- At the International Center for Spinal Cord Injury (ICSCI), we are constantly assessing our therapeutic interventions' effectiveness, continuing to develop new and improved technology, and testing new clinical interventions, in order to improve patient care and advance the field of spinal cord rehabilitation and restoration. (kennedykrieger.org)
- The International Center for Spinal Cord Injury team is not only conducting our own clinical research, we are actively engaging with the wider medical and rehabilitation community to share our research with other similar centers and to learn about the latest research breakthroughs happening in clinics and laboratories all over the world. (kennedykrieger.org)
- A person can 'break their back or neck' yet not sustain a spinal cord injury if only the bones around the spinal cord (the vertebrae) are damaged, but the spinal cord is not affected. (makoa.org)
- The spinal cord is protected by 33 vertebrae, ring-shaped bones that protect the spinal cord from injury. (klinespecter.com)
- Damage to the vertebrae, the bones protecting the spinal cord, can occur without there being a spinal cord injury. (klinespecter.com)
- During the lumbar puncture procedure, an experienced anesthesiologist injects the stem cells into the spinal canal through the lower vertebrae under local anesthesia. (cellmedicine.com)
- With no currently available drug treatment for spinal cord injury, there is a need for additional therapeutic candidates. (sigmaaldrich.com)
- Thanks to this animal model, it was clear that CBP is a key molecule, capable of becoming a therapeutic target to increase regeneration after spinal cord injury. (ndtv.com)
- It is thus important to pursue research on all aspects of spinal cord injury, hoping that understanding basic mechanisms involved in spinal cord injury will continue to establish therapeutic strategies designed to alleviate such sensorimotor deficits and favor a better social reintegration of SCI patients. (jneurosci.org)
- While these studies have so far shown no untoward effects of stem cells after transplantation into the spinal cord, the therapeutic benefits are yet to be fully understood. (spinerf.org)
- Cell transplantation, as a therapeutic intervention for spinal cord injury (SCI), has been extensively studied by researchers in recent years. (hindawi.com)
- Our goal is to progress this treatment forward for use as a therapeutic following spinal cord injury. (medindia.net)
- Focused ultrasound is an early-stage, noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with spinal cord injury. (fusfoundation.org)
- For certain patients, focused ultrasound could provide a noninvasive means of delivering therapeutic agents to the injured cord to improve recovery. (fusfoundation.org)
- As a first action under this IND, the Company is working to open U.S. sites for its Phase I/II clinical trial for chronic spinal cord injury, which is currently underway in Switzerland and Canada. (nationalreview.com)
- 3. Will a cure work for chronic spinal cord injury? (rutgers.edu)
- Third, while chronic spinal cord injury studies in animals are still very limited, the fact that many people continue to recover some function years after injury provide hope that these therapies will also work in chronic spinal cord injury. (rutgers.edu)
- After time, the injury either heals (if it was not severe) or it becomes chronic, and perhaps permanent. (answers.com)
- Association between mobility mode and C-reactive protein levels in men with chronic spinal cord injury. (medscape.com)
- We've shown for the first time that spinal cord injuries (SCI) lead to a chronic state of poor blood flow and lack of oxygen to neuronal networks in the spinal cord," says co-principal investigator Karim Fouad, professor, Faculty of Rehabilitation Medicine and Canada Research Chair for spinal cord injury. (eurekalert.org)
- Published in Nature Medicine on May 1, 2017, the study demonstrates chronic ischemic hypoxia (lack of blood and oxygen) after spinal cord injury and how blood flow plays a key role in the cause and treatment of motor disorders. (eurekalert.org)
- This surprising finding led them to make basic measurements of blood flow and oxygenation below the spinal cord, which led to the discovery of the chronic ischemic hypoxia. (eurekalert.org)
- Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury. (clinicaltrials.gov)
- Recently, the investigators demonstrated that daily (5 consecutive days) of intermittent hypoxia stimulated walking enhancement in persons with chronic spinal cord injury. (clinicaltrials.gov)
- The investigators hypothesize that repetitive exposures (3 times per week for 4 weeks) to modest bouts of low oxygen will enhance and prolong walking recovery in persons with chronic spinal cord injury. (clinicaltrials.gov)
- yet so often remain compromised after chronic injury. (clinicaltrials.gov)
- By providing input above and below the level of injury, activity based rehabilitation promotes neural recovery and reorganization while offsetting chronic complications, improving function, and facilitating achievement of milestones. (acrm.org)
- More recently, Stem Cells Inc. has begun another study transplanting stem cells for chronic spinal cord injury (four months to two years after injury). (spinerf.org)
Bundle of nerves4
- The spinal cord is the major bundle of nerves that carry nerve impulses to and from the brain to the rest of the body. (makoa.org)
- An injury to the spinal cord, the bundle of nerves residing in the backbone, can result in the loss of motor control and sensation, it can render the injured person fully or partly paralyzed, and can do permanent and serious harm to bodily functions, such as breathing. (lawinfo.com)
- The spinal cord is made up of a bundle of nerves that run from the base of the brain down the middle of the back to a point just above the waist. (klinespecter.com)
- The spinal cord is simply a bundle of nerves. (gorenlaw.com)
- Depending on your level of injury, severity, and complications, you may need to see a variety of specialists and therapists over your lifetime. (craighospital.org)
- Other injuries cause lifelong disability, and complications from severe spinal cord injuries can lead to infection and death. (dudeklawfirm.com)
- Are There Likely Complications With This Type of Injury? (defranciscolaw.com)
- Because certain areas of the body can be cut off from nerve communications with the brain due to this type of injury, there are a lot of complications that may arise. (defranciscolaw.com)
- Many people who suffer from a spinal injury may also experience depression due to the changes in lifestyle required to cope with the initial injury and following complications. (defranciscolaw.com)
- People with spinal cord injuries may also suffer bowel or bladder complications, or experience problems breathing and require a respirator or other breathing apparatus. (klinespecter.com)
- Spinal cord injuries also can lead to many complications, including pressure sores and increased susceptibility to respiratory diseases. (healthofchildren.com)
- In either case, the time between injury and treatment is critical and can significantly influence the extent of complications and the level of recovery. (healthofchildren.com)
Patients with spinal2
American Spinal Injury Association3
- American Spinal Injury Association. (medscape.com)
- What are the categories of the American Spinal Injury Association (ASIA) Impairment Scale of spinal cord injury (SCI)? (medscape.com)
- He serves as chair of the advocacy committees for the American Spinal Injury Association and the Academy of Spinal Cord Injury Professionals. (cdc.gov)
Levels of spinal cord i1
- Injuries in the thoracic region usually affect the chest and the legs and result in paraplegia. (makoa.org)
- Injuries at the thoracic level and below result in paraplegia, with the hands not affected. (makoa.org)
- The profound consequences of permanent spinal injury (leading to problems like paraplegia) have motivated a lot of biomedical research, but best is to avoid the accident. (answers.com)
- Paraplegia is a common result of injuries throughout the thoracic level of the spinal cord. (cooperhurley.com)
- Severe spinal cord injuries can also affect a person's automatic activity such as breathing and bowel or bladder activity. (burke.org)
- On the other hand, I believe that there will be effective therapies that will restore function to people with spinal cord injury, including touch and pain sensations, bladder and bowel function, erection and ejaculation, and motor control including long-distance walking. (rutgers.edu)
- Depending on the level of injury, the brain may not be able to communicate with the bladder or bowels, and changes in control may require new techniques to avoid infection. (hauptman-obrien.net)
- You may have heard it from physicians, from family members who have been doing their reading, or from spinal cord injury survivors who go to other doctors or who were treated at different hospitals or rehabilitation centers: "You're going to develop cancer of the bladder if you keep that catheter in. (craighospital.org)
- Is the risk of bladder cancer higher in spinal cord injury survivors? (craighospital.org)
- Just how much more common is bladder cancer among spinal cord injury survivors? (craighospital.org)
- The truth is that bladder cancer is more common people with spinal cord injury than in the general population. (craighospital.org)
- In spinal cord injury, the incidence of bladder cancer varies with each study. (craighospital.org)
- However, multiple studies have found an increased rate of bladder cancer (Consortium for Spinal Cord Medicine, 2006). (craighospital.org)
- However, it should also be noted that squamous cell cancer is rare, so even though there is a greater incidence in those with spinal cord injury, the number of individuals who develop squamous cell bladder cancer is actually low" (Consortium of Spinal Cord Injury, 2006, p. 23). (craighospital.org)
- Many scientists and researchers suspect that spinal cord injury, because of the way it changes the urinary system and alters the environment inside the bladder, may increase the amount and types of irritation the bladder is subject to. (craighospital.org)
- In addition to the irritation they cause, some researchers suspect that urinary tract infections cause the release of a substance in the bladder, called nitrosamine (Consortium of Spinal Cord Injury, 2006). (craighospital.org)
- All spinal cord injuries may result in a loss of bladder control, sexual function, sensation, motor skills, and involuntary functions. (cooperhurley.com)
- For example, someone with a spinal cord injury may no longer be able to control his or her bowel, respiratory system or bladder. (defranciscolaw.com)
- Treating your spinal cord injury often includes physical and occupational therapy, bowel and bladder management training, respiratory system improvement, and working with our multidisciplinary team to get the education and skills you need to transition home or to further care. (hfsc.org)
- We took the approach of repositioning existing pharmacological agents to serve as acute treatments for spinal cord injury and previously found imatinib to have positive effects on locomotor and bladder function in experimental spinal cord injury when administered immediately after the injury. (sigmaaldrich.com)
- Here, we show that imatinib improves hind limb locomotion and bladder recovery when initiation of treatment was delayed until 4 h after injury and that bladder function was improved with a delay of up to 24 h. (sigmaaldrich.com)
- The extent to which a spinal cord injury will lead to bladder and bowel problems depends largely on two factors: whether the injury is complete or incomplete and the level of the spinal cord injury (high/low). (coloplast.co.uk)
- Learn more about spinal cord injury and bladder problems and how to take care of your bladder . (coloplast.co.uk)
- About 80% of people with a spinal cord injury (SCI) will experience bladder dysfunction. (coloplast.co.uk)
- The impact of a spinal cord injury on the bladder can result in involuntary messages to contract the bladder being received by the bladder causing leakage, or wetting. (coloplast.co.uk)
- Most people with a spinal cord injury will experience bladder dysfunction known as neurogenic bladder, which means they have a decreased ability to control their bladder. (coloplast.co.uk)
- Spinal cord injury organizations are working with CDC to increase awareness and educate health care providers about a rational approach to bladder management in spinal cord injury patients in acute care hospitals. (cdc.gov)
- For any spinal cord-injured patient today, it would be considered extraordinary to regain even one of these functions, especially bladder function. (medindia.net)
- Following, our experienced personal injury lawyers present the answers to some frequently asked questions about spinal cord injuries and related lawsuits. (hauptman-obrien.net)
- Often, personal injury lawyers do not take money upfront. (spinalcordinjurylawyers.com)
- Personal injury lawyers usually charge their clients a small percentage of their awarded compensation after the lawsuit is complete. (spinalcordinjurylawyers.com)
- Personal injury lawyers may also deduct any upfront costs from the total awarded compensation. (spinalcordinjurylawyers.com)
- If you have questions about your spinal cord injury, caused by the negligence of another, that you would like to have answered by one of our Norfolk spinal cord injury lawyers , please contact Cooper Hurley Injury Lawyers today to schedule a free consultation . (cooperhurley.com)
- He has more than 20 years of experience handling personal injury cases and recently handled the largest auto accident settlement in 2010, according to VA Lawyers Weekly. (cooperhurley.com)
- In 2014, Mr. O'Mara joined Cooper Hurley Injury Lawyers as an associate attorney. (cooperhurley.com)
- Greene & Schultz Trial Lawyers has experience helping clients with their Spinal Cord Injury needs in Indianapolis, Indiana. (lawinfo.com)
- At Hull & Zimmerman, P.C., we are honored to help accident victims in their time of need, and take our responsibility as personal injury lawyers incredibly seriously. (hullandzimmerman.com)
Cure for spinal cord inj2
Severe spinal cord inj2
- According to the Christopher and Dana Reeve Foundation , severe spinal cord injuries cost more than $1 million the first year and incur high annual costs each year after. (hauptman-obrien.net)
- Less severe spinal cord injuries can lead to either complete loss of movement with some feeling, or loss of feeling in the arms but not the legs. (1stclaims.co.uk)
Cause of spinal cord inj2
- The Mayo Clinic of physicians, scientists and researchers lists car accidents as the leading cause of spinal cord injuries. (camllp.com)
- According to the Centers for Disease Control, auto accidents such as car accidents and motorcycle accidents are the number one cause of spinal cord injuries. (dudeklawfirm.com)
Individuals with spinal cord inj3
- All caregivers, practitioners, and therapists who interact with individuals with spinal cord injuries must be aware of this syndrome, recognize the symptoms, and understand the causes and treatment algorithm. (medscape.com)
- In individuals with spinal cord injuries, does the presence of a pressure injury alter calorie and protein requirements? (pennutrition.com)
- Do individuals with spinal cord injuries (SCI) have an increased prevalence of cardiovascular disease (CVD)/cardiometabolic risk? (pennutrition.com)
Serious spinal cord inj1
Sustain a spinal cord i1
- We are leaving behind the days of using pills to treat symptoms, and entering a new era where we're using living human cells to permanently restore organ function damaged by a disease or an injury," said Tom O'Karma, president and CEO of Geron Corporation, the company conducting the trial. (go.com)
- How long does a spinal cord injury take to show signs or symptoms? (hauptman-obrien.net)
- In most cases, the signs and symptoms of a spinal cord injury are instantly apparent. (hauptman-obrien.net)
- I think the most important questions for EPs include what the incidence is of Cervicoligamentous injury or spinal cord injury with negative CT, and what are risk factors (possibly mechanism of injury, age, etc) and clinical factors (I.e possibly severity of neck pain after collar removal, focal neuro symptoms, etc) that alter the probability of having this. (emlyceum.com)
- Mental Confusion ADD symptoms, speech probs- from back injury? (spineuniverse.com)
- What other symptoms are there in spinal cord injuries? (klinespecter.com)
- This study proposes to test the efficacy of Venlafaxine HCI in reducing mild to moderate symptoms of depression among persons with Spinal Cord Injury (SCI). (clinicalconnection.com)
- Autonomic Dysreflexia presents with a unique and bewildering set of symptoms, and studies have shown that non-specialty healthcare providers receive little or no training in recognition and treatment of Autonomic Dysreflexia - nor do they see sufficient numbers of spinal cord injury patients to maintain competency once this training has been given. (cdc.gov)
- SCI symptoms usually appear immediately after the injury. (healthofchildren.com)
- However, symptoms can develop slowly, if an infection or tumor is gradually increasing pressure on the spinal cord. (healthofchildren.com)
- These are what I call the first generation therapies which include treatments like weight-supported treadmill ambulation training, decompression and untethering of a spinal cord that is compressed. (rutgers.edu)
- These include possible combination cell transplant therapies with growth factors and other treatments that stimulate regeneration of the spinal cord. (rutgers.edu)
- What are the treatments for Spinal Cord Injury? (camllp.com)
- There are various treatments available for spinal chord injury. (answers.com)
- Some of these treatments could be planned concurrently with neurosurgical approaches that are themselves beneficial to decrease secondary damage (e.g., decompression/reconstructive spinal surgery). (jneurosci.org)
- Guidelines related to spinal cord injuries treatments are focused on avoidance of secondary injury from compressive lesions and hemodynamic instability. (medscape.com)
- Research within the Krembil is directed at the development of treatments for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease), epilepsy, stroke, brain tumours, concussions, spinal cord injuries, neurophthalmologic and other ocular disorders, multiple sclerosis and autoimmune disorders. (wikipedia.org)
- At the Krembil, neuroscientists explore the function of the nervous system as they develop treatments for neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, epilepsy, spinal cord injuries, cerebral ischemia (stroke), vascular brain malformations, aneurysms, brain tumours and pain disorders. (wikipedia.org)
- Afferents below the lesion undergo specific rearrangements soon after injury, and without them regained motor function cannot be maintained, even if detour circuits have formed. (eurekalert.org)
- Finally, rehabilitative approaches based on the presence of functional networks (i.e., central pattern generator) below the lesion combined with the above neurobiological approaches may produce significant functional recovery of some sensorimotor functions, such as locomotion, by ensuring an optimal function of endogenous spinal networks and establishing new dynamic interactions with supralesional structures. (jneurosci.org)
- The repair of the spinal cord requires a good knowledge of the mechanisms of the lesion itself, of axonal growth, of anatomical and functional organization of the spinal cord, as well as of other structures of the CNS. (jneurosci.org)
- Figure 1 schematically represents (left) a spinal lesion that usually results in a cavitation with various degrees of local damage. (jneurosci.org)
Nerves after a spinal cord i1
- The most common causes of spinal cord injuries are road traffic accidents, sporting accidents, work accidents, industrial disease and medical negligence . (1stclaims.co.uk)
- Contact 1stClaims today if you want to know more about claiming for spinal injury following medical negligence. (1stclaims.co.uk)
- Because many spinal cord injuries are caused by accidents or medical negligence, a back injury lawyer experienced with spinal cord injuries can help your family cope with the financial burden associated with the injury. (gorenlaw.com)
- SCI can be divided into two types of injury - complete and incomplete. (makoa.org)
- An incomplete injury means that there is some functioning below the primary level of the injury. (makoa.org)
- A person with an incomplete injury may be able to move one limb more than another, may be able to feel parts of the body that cannot be moved, or may have more functioning on one side of the body than the other. (makoa.org)
- Remember that in incomplete injuries there will be some variation in these prognoses. (makoa.org)
- Spinal cord injuries are divided into two types - incomplete and complete. (tripr.tv)
- In the case of incomplete injuries, some functioning may be restored after months and even years. (tripr.tv)
- Incomplete spinal cord injury? (answers.com)
- An incomplete spinal cord injury happens when only part of the spinal cord is damaged. (answers.com)
- WebMD points out that incomplete injuries are classified depending on where the damage occurred and what functions the person is still able to perform. (defranciscolaw.com)
- Incomplete injuries, where only part of the neuronal connections are damaged, frequently recover spontaneously," adds Takeoka. (eurekalert.org)
- Spinal string harm is the aftereffect of traumatic harm, for example, a wound or injury, an incomplete tear or a total tear in the spinal string. (authorstream.com)
- S4-S5 indicate an incomplete injury. (studystack.com)
Brain and the spinal cord3
- The brain and the spinal cord constitute the Central Nervous System. (makoa.org)
- Spinal cord injury disconnects communication between the brain and the spinal cord, disrupting control over part of the body. (eurekalert.org)
- The brain and the spinal cord play a key role in controlling bodily functions. (coloplast.co.uk)
- It is important to contact a personal injury lawyer as soon as possible. (spinalcordinjurylawyers.com)
- How can a lawyer help me with my personal injury case? (spinalcordinjurylawyers.com)
- Specifically, hiring a lawyer who has experience handling cases with your type of injury will help maximize the chances of you winning your case. (spinalcordinjurylawyers.com)
- How much does a personal injury lawyer cost? (spinalcordinjurylawyers.com)
- Can I file a personal injury lawsuit without a lawyer? (spinalcordinjurylawyers.com)
- The personal injury lawsuit process is complex, and you are subject to all of the same rules and regulations without a lawyer as you would be with a lawyer. (spinalcordinjurylawyers.com)
- After you experience a catastrophic injury, it is essential to discuss the facts of your injury with an experienced lawyer to determine if you have a case. (spinalcordinjurylawyers.com)
- Personal injury lawyer Frederick M. Dudek has litigated many cases on behalf of people with spinal cord injuries . (dudeklawfirm.com)
- How Can A Brain And Spinal Cord Injury Lawyer Help Me? (brainandspinalcord.org)
- If you need to file a lawsuit in your case, having a brain and spinal cord injury lawyer on your side already can make this process much easier. (brainandspinalcord.org)
- Is you have suffered a spinal cord injury , it is in your best interest to consult a Washington lawyer. (lawinfo.com)
- If you or someone you know has suffered a spinal cord injury, you may want to contact a spinal cord lawyer for a free evaluation of your case. (klinespecter.com)
- Call (888) 777-7098 to get connected with an Easton spinal cord injury lawyer here at Drake, Hileman & Davis, PC. (dhdlaw.com)
- If you'd like to setup a free consultation with an Easton spinal cord injury lawyer, call (888) 777-7098 today. (dhdlaw.com)
- Spinal cord injuries can result in emotional and financial burdens not just for victims, but also their families,' says New York personal injury lawyer Kenneth A. Wilhelm. (prweb.com)
- In fact, in most people with SCI, the spinal cord is intact, but the damage to it results in loss of functioning. (makoa.org)
- The spinal cord provides the communication between the brain and the muscles and organs of the body, much like a telephone between two people. (burke.org)
- Do people with spinal cord injury ever improve? (tripr.tv)
- Can people with spinal cord injury hold jobs? (tripr.tv)
- There is no reason why people with spinal cord injuries cannot be employed productively. (tripr.tv)
- Americans with Disabilities Act envisages the inclusion of people suffering from spinal cord injuries in the mainstream of society. (tripr.tv)
- Is it possible for people with spinal cord injuries to have sex and children? (tripr.tv)
- If a cure means complete restoration of all function to 'normal' or pre-injury levels for all people with spinal cord injury, I think that that this is unlikely because we probably will not have therapies that can completely reverse aging and changes of the body due to the injury. (rutgers.edu)
- Clinical research involves people (research participants) and is designed to answer specific medical questions. (kennedykrieger.org)
- While many people may have a basic understanding of a spinal cord injury, there are some things that not a lot of people understand. (fibichlaw.com)
- Because of this, we want to make sure people understand the potential issues that are associated with spinal cord injury, the severity of the injuries, and the potential expenses victims can expect. (fibichlaw.com)
- Most states have a statute of limitations of 2 years for personal injury cases, meaning people only have two years to file a claim after the day they were injured. (spinalcordinjurylawyers.com)
- People with spinal cord injuries who use indwelling catheters have higher rates of developing this type of cancer (Consortium of Spinal Cord Injury, 2006). (craighospital.org)
- Mary Free Bed's John F. Butzer Center for Research & Innovation is engaged in research efforts to improve the quality of life for people living with spinal cord injury. (maryfreebed.com)
- The hospital has been awarded a three-year, $400,000 grant from the Craig H. Neilsen Foundation to measure how physical activity impacts the lives of people with spinal cord injury. (maryfreebed.com)
- Mary Free Bed Rehabilitation Hospital and the Mary Free Bed YMCA have collaborated to offer an FES cycling program for people with traumatic spinal cord injury. (maryfreebed.com)
- Project Walk, the world leader in spinal cord injury recovery, provides an improved quality of life for people with a spinal cord injury through intense activity-based recovery programs, education, training, research and development. (prweb.com)
- Most people with spinal cord injury go through a rehabilitation programme with the goal of living as full and independent a life as possible. (coloplast.co.uk)
- The spinal cord research registry contains the names of people who are diagnosed with a spinal cord injury and would like to be informed about the research studies at NewYork-Presbyterian Hospital/Columbia University Medical Center. (nyp.org)
- The findings explained why people who have led an 'active lifestyle' recover more after spinal cord injury than those with 'less active' lifestyles. (ndtv.com)
- Once verified, it could potentially be combined with neurorehabilitation to treat people who have suffered a spinal cord injury. (ndtv.com)
- According to the National Spinal Cord Injury Statistical Center, estimates from several studies suggest that the number of people in the U.S. living with spinal cord injury is between 243,000 and 347,000. (medicalnewstoday.com)
- The following is a list of general questions that pertain to the majority of people. (braininjuryselfrehabilitation.com)
- It's also possible that CTGF doesn't switch on in people after an injury in the same way it does in the fish. (nih.gov)
- There are currently no drug therapies available that improve the very limited natural recovery from spinal cord injuries that patients experience," said Lyn Jakeman, PhD, a program director at the NIH's National Institute of Neurological Disorders and Stroke, Bethesda, Md. "This is a great step toward identifying a novel agent for helping people recover. (medindia.net)
- Traumatic spinal cord injury (SCI) brings about dramatic and long-term change in both the biological body and the social, psychological and occupational worlds that people inhabit. (helpforheroes.org.uk)
- People with spinal injury go through complex psychological states and it may take many years for them to reach psychological stability and acceptance (Dickson et al. (helpforheroes.org.uk)
- At Fibich, Leebron, Copeland & Briggs, our Houston spinal cord injury attorneys understand that this type of situation can be difficult. (fibichlaw.com)
- If the injury was caused by another's negligence, the Omaha attorneys at Hauptman, O'Brien, Wolf & Lathrop are here to help you understand your legal options and pursue compensation on your behalf. (hauptman-obrien.net)
- Our spinal cord injury attorneys have offices in Norfolk and Virginia Beach, serving the Hampton Roads area, Chesapeake, Portsmouth, and Newport News, Virginia. (cooperhurley.com)
- Lead Counsel independently verifies Spinal Cord Injury attorneys in Washington by conferring with District of Columbia bar associations and conducting annual reviews to confirm that an attorney practices in their advertised practice areas and possesses a valid bar license for the appropriate jurisdictions. (lawinfo.com)
- Please contact our New York personal injury attorneys TOLL FREE 24 hours a day, 7 days a week at 1-800-WORK-4-YOU (1-800-967-5496). (prweb.com)
- Our spinal cord injury attorneys work on a contingent-fee basis, taking a percentage of the amount recovered to pay our fee. (gorenlaw.com)
- Briefly, autonomic dysreflexia develops in individuals with a neurologic level of spinal cord injury at or above the sixth thoracic vertebral level (T6). (medscape.com)
- The spinal cord is soft and fragile, but well protected by surrounding bones in the vertebral column. (answers.com)
- This entry was posted in Uncategorized and tagged canadian , collar , neurogenic shock , nexus , spina cord injury , vertebral compression . (emlyceum.com)
- In studies of contusion SCI in the rat using mitogen-expanded cells, we have shown that SC transplantation at seven days after injury significantly fosters axon regeneration and myelination, improves host tissue preservation, 4 and reduces cavitation 4,14 in a thoracic SCI paradigm and increases numbers of preserved NeuN positive neurons rostral and caudal to the injury/graft site 17 after cervical SCI. (genengnews.com)
- The primary end-point was to evaluate the safety through a one year follow-up when ahSCs were administered at one of three doses within 72 days of injury to participants with complete thoracic SCI. (genengnews.com)
- In general, the higher in the spinal column the injury occurs, the more dysfunction a person will experience. (makoa.org)
- When a spinal cord injury occurs, communication can be stopped, resulting in a loss of function in the body and a loss of independence for the patient. (burke.org)
- The higher on the spinal cord an injury occurs, the more extensive the damage may be. (hauptman-obrien.net)
- The degree of disability depends on the extent of the injury and where along the spinal cord it occurs. (coloplast.co.uk)
- Axon damage occurs not only in strokes and brain and spinal cord injuries, but also in many other diseases, including multiple sclerosis and a range of neurodegenerative disorders. (medicalnewstoday.com)
- Arachnoiditis occurs when injury to the spinal cord causes the inflammation of the membrane that surrounds these important nerves. (hullandzimmerman.com)
- The common causes of spinal cord injury are traumatic incidents like a gunshot, automobile accidents, falls, etc. and diseases like spina bifida, polio, Friedreich's Ataxia, etc. (tripr.tv)
- According to the National Spinal Cord Injury Association (NSCIA), spinal cord injuries are caused in the United States by motor vehicle accidents (44%), acts of violence (24%), falls (22%), sports (8%), and other causes (2%) such as abscesses, tumors, polio , spina bifida and Friedrich's Ataxia, a rare inherited disorder. (healthofchildren.com)
- While this growth factor by itself is unlikely to produce significant spinal cord regeneration in human patients, the findings do offer a promising lead for researchers pursuing the next generation of regenerative therapies. (nih.gov)
- Injury-induced ctgfa directs glial bridging and spinal cord regeneration in zebrafish . (nih.gov)
- Based on their clear role in successful axon regeneration, the idea arose to test whether purified populations of SCs could mediate re-growth of axons and myelin in the damaged spinal cord, where they are not present normally. (genengnews.com)
Human spinal cord2
Flexors and legs2
- What's particularly encouraging to those looking for ways to help the 12,000 Americans who suffer spinal cord injuries each year is that humans also produce a form of CTGF. (nih.gov)
- There needs to be a balance between removing catheters to prevent infections and ensuring spinal cord injury patients do not suffer unintended consequences that could threaten their lives. (cdc.gov)
Causes of spinal1
Percent of spinal2
- Approximately 90 percent of spinal cord injuries are due to traumatic events, with motor vehicles accidents causing approximately 38 percent of SCIs, according to the National Spinal Cord Injury Statistic Center (NSCISC). (burke.org)
- Fifty to ninety percent of spinal cord injury patients are susceptible to Autonomic Dysreflexia. (cdc.gov)
Recovery from spinal1
- Injuries to the five Lumbar vertebra (L-1 thru L-5) and similarly to the five Sacral Vertebra (S-1 thru S-5) generally result in some loss of functioning in the hips and legs. (makoa.org)
- After partial disruption of the BBB by compression of the lumbar spinal cord, permeability to TNF was increased not only in the lumbar spinal cord but also in brain and distal spinal cord segments, where the BBB remained intact. (jneurosci.org)
- Depending on the injury's severity, some indicators may not be noticeable until days or weeks following the injury. (hauptman-obrien.net)
- Whilst spinal cord injuries can differ in severity, largely whatever the nature of the injury the impact on the victim's life can be substantial. (1stclaims.co.uk)
- The location and extent of the trauma determines the severity of the injury. (gorenlaw.com)
- Your sexual response will depend on the location and severity of your spinal cord injury (SCI). (drugs.com)
- The lead author Yaqing (Celia) Li, rehabilitation science post-doctoral fellow, and David Bennett, co-principal investigator and professor, Faculty of Rehabilitation Medicine, were looking at the injured spinal cord of a rat under a microscope and noticed the capillaries contracting in response to application of dietary amino acids like tryptophan. (eurekalert.org)
- Most studies show that the incidence of SCI in males is at least twice as much as injury among females. (burke.org)
- It is estimated that the worldwide annual incidence of spinal cord injury (SCI) is 22 per million of population and that there are actually ∼2.5 million survivors of SCI ( http://www.rickhansenregistry.org/page192.htm ). (jneurosci.org)