The development by insects of resistance to insecticides.

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... Jennifer R. Gordon, James ... Jennifer R. Gordon and James Ottea "Association of Esterases with Insecticide Resistance in Culex quinquefasciatus (Diptera: ... Jennifer R. Gordon, James Ottea "Association of Esterases with Insecticide Resistance in Culex quinquefasciatus (Diptera: ... However, these management programs have been compromised by development of insecticide resistance. In the current study, ...
Characterization of a B-type esterase involved in insecticide resistance from the mosquito Culex quinquefasciatus Biochem J ( ... Purification and characterization of a carboxylesterase involved in insecticide resistance from the mosquito Culex ... Purification and characterization of a carboxylesterase involved in insecticide resistance from the mosquito Culex ... involved in organophosphate insecticide resistance has been purified and characterized from the mosquito Culex quinquefasciatus ...
This situation of resistance may seriously jeopardize the efficacy of Insecticide Residual Spray (IRS) and Long-Lasting ... which were significantly higher in areas where farmers used insecticides for pests control than in areas where no insecticides ... There is more information on the resistance status to malaria vectors compared to Culicines. It is therefore unfortunate that ... quinquefasciatus to insecticide-impregnated papers (permethrin 0.75%, delthamethrin 0.05%, DDT 4%, and bendiocarb 0.1%) ...
... insecticide resistance, PYRETHROID RESISTANCE, IMPREGNATED BEDNETS, DIELDRIN-RESISTANCE, DDT-RESISTANCE, KDR MUTATION, TREATED ... Culex, drug effects, enzymology, genetics, Drug Resistance, Multiple, genetics, Female, Genotype, Insecticide Resistance, ... Multiple insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasciatus from Benin, West Africa ... Carbamate/OP resistance was present at higher frequency in Culex than in An. gambiae. Dieldrin resistance was present in both ...
quinquefasciatus control in Brazil, the selection of insecticide resistance is likely due in part to the well-designed chemical ... quinquefasciatus in Brazil since the 1950s and insecticide resistance data registered in the literature. As there is no ... There are very few publications about insecticide resistance in Cx. quinquefasciatus from Brazil when compared to Ae. aegypti. ... Nevertheless, resistance to organophosphates, carbamate, DDT, pyrethroids and biolarvicides has been registered in Cx. ...
Mosquitoes Culex pipiens is a major vector species for Japanese encephalitis and filariasis in China, and it is an important ... Insecticide Resistance in Culex pipiens pallens Mosquitoes Zhu, Changliang Nanjing Medical University, Nanjing, China ... Insecticide Resistance in Culex pipiens pallens Mosquitoes. Zhu, Changliang / Nanjing Medical University. $94,638. ... Insecticide Resistance in Culex pipiens pallens Mosquitoes. Zhu, Changliang / Nanjing Medical University. $94,638. ...
RESEARCH NOTE Culex quinquefasciatus Say 1823 is a vector of equine encephalitis and filariasis, and is one of the ... Insecticide Resistance in a Culex quinquefasciatus Strain from Rio de Janeiro, Brazil ... Malathion resistance is not yet extensive in the population, so insecticide rotation of pyrethroids and malation may be the ... If these enzymes are involved in the resistance to an insecticide, the effect will be higher when using the compound that ...
Detection of this altered target site mutation is important in guiding informed decisions for resistance management. In this ... Insecticide resistance to organophosphates and carbamates can be the result of changes in acetylcholinesterase activity ... Insecticide resistance in Culex quinquefasciatus Say, 1823 in Brazil: a review. Lopes RP, Lima JBP, Martins AJ. Lopes RP, et al ... Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de ...
We compared Culex quinquefasciatus mosquitoes harbouring two resistance alleles ace-1 R and Kdr R (conferring resistance to ... Each resistance allele was associated with fitness costs (survival to adulthood) in an insecticide-free environment, with the ... The two insecticides combined in an additive, synergistic and antagonistic manner depending on a mosquitos resistance status, ... Insecticide resistance mutations interacted to positively or negatively influence a mosquitos fitness, both in the presence or ...
Global spread and genetic variants of the two CYP9M10 haplotype forms associated with insecticide resistance in Culex ... haplotype forms associated with insecticide resistance in ,i,Culex quinquefasciatus,/i, Say . Opens in a new window. ...
Full text: Available Index: LILACS (Americas) Main subject: Insecticide Resistance / Culex Limits: Animals Country/Region as ... Full text: Available Index: LILACS (Americas) Main subject: Insecticide Resistance / Culex Limits: Animals Country/Region as ... Animals , Culex/drug effects , Insecticide Resistance , Acetylcholinesterase/drug effects , Brazil , Esterases/drug effects ... Insecticide resistance in a Culex quinquefasciatus strain from Rio de Janeiro, Brazil ...
... but this fact did not seem to contribute to resistance. Pyrethroid resistance in An. gambiae appears to threaten the future of ... A trial to test the continuing efficacy of insecticide-treated nets (ITN) and indoor residual spraying (IRS) was undertaken in ... The pyrethroid knockdown resistance gene (kdr) has become widespread in Anopheles gambiae in West Africa. ... Experimental hut results of lambdacyalothrin (insecticide)-treated nets (ITNs) and indoor residual spraying (IRS) against Culex ...
Insecticide susceptibility of ,i,Culex quinquefasciatus,/i, was assessed with permethrin (1%), DDT (4%), bendiocarb (0.1%), ... Additional studies with ,i,Culex,/i, species are recommended to know whether the difference in blood feeding is interspecific ( ... PermaNet 3.0 unwashed deterred 16.84% ,i,Culex,/i, mosquitoes. After 20 washes, it deterred 5.79% mosquitoes compared to 6.84% ... quinquefasciatus,/i, was resistant to tested insecticides (6%-50% mortality). PermaNet 3.0 is a good control tool against ...
In the mosquito Culex pipiens (L.) (Diptera: Culicidae) esterases contribute to insecticide resistance by their increased ... To provide resistance assessment for the national insecticide resistance management program, we collected a total of 42 samples ... These data suggest that lack of fitness costs related to insecticide resistance may accelerate the development of insecticide ... KEYWORDS: Diatraea saccharalis, Bt corn, resistance monitoring, insecticide resistance management, cornstalk borers. ...
However, high temephos resistance ratios were still detected between 2001 and 2004. Field-simulated assays confirmed a low ... Data are discussed in the context of historic application of insecticides in Brazil. ... Aedes aegypti resistance to temephos, used since 1967, was detected in several municipalities in 2000. Organophosphates were ... Insecticide resistance in the mosquito Culex pipiens: what have we learned about adaptation? Genetica 112-113 : 287-296.. ...
Independent duplications of the acetylcholinesterase gene conferring insecticide resistance in the mosquito Culex pipiens. ... Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens. ... Resistance Gene Replacement in the mosquito Culex pipiens: fitness estimation from long-term cline series. ... GENE-dosage effects on fitness in recent adaptive duplications: ace-1 in the mosquito Culex pipiens. ...
Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus. ... Insecticide resistance in Anopheles gambiae from the northern Democratic Republic of Congo, with extreme knockdown resistance ( ... Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: evidence from health ... LLIN Evaluation in Uganda Project (LLINEUP): a cross-sectional survey of species diversity and insecticide resistance in 48 ...
Experimental hut results of lambdacyalothrin (insecticide)-treated nets (ITNs) and indoor residual spraying (IRS) against Culex ... His current research interests are on insecticide resistance in Anopheles gambiae and identifying alternative insecticides to ... funestus and necessitated a switch to an alternative class of insecticide to which there was no resistance (6). During the last ... Reduced Efficacy of Insecticide-treated Nets and Indoor Residual Spraying for Malaria Control in Pyrethroid Resistance Area, ...
Insecticide resistance in Culex pipiens from New York. J Am Mosq Control Assoc 21: 305-309.[Crossref]. [Google Scholar] ...
"Population genetics of insecticide resistance in the mosquito Culex pipiens" (PDF). Biol. J. Linn. Soc. 68 (1-2): 147-57. doi: ... Walls of properties are sprayed with an insecticide, the mosquitoes die when they land on the surface covered in insecticide. ... in the mosquitoes Culex salinarius Coquillett and Culex tarsalis Coquillett" (PDF). Journal of the Florida Anti-Mosquito ... Shifting the water with larvae to another vessel and pouring a few drops of kerosene oil or insecticide/larvicide in it is ...
"Forty years of erratic insecticide resistance evolution in the mosquito Culex pipiens". PLOS Genetics. 3 (11): e205. doi: ... Pan D, Xue W, Zhang W, Liu H, Yao X (October 2012). "Understanding the drug resistance mechanism of hepatitis C virus NS3/4A to ... These same problems occur in agriculture with pesticide and herbicide resistance. It is possible that we are facing the end of ... Schenk MF, Szendro IG, Krug J, de Visser JA (June 2012). "Quantifying the adaptive potential of an antibiotic resistance enzyme ...
Malaria mortality rates in sub-Saharan Africa have declined significantly in recent years as a result of increased insecticide- ... Multiple insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasciatus from Benin, West Africa. Acta Trop. ... Insecticide resistance bioassays. To test if metabolic insecticide resistance (P450-related) and overall insecticide resistance ... have been associated with insecticide resistance in anophelines. Insecticide resistance ultimately is the combination of ...
Read chapter Genetics and Biochemistry of Insecticide Resistance in Arthropods: Prospects for the Future: Based on a symposium ... Comparative modification of insecticide-resistance spectrum of Culex pipiens fatigans Wied. by selection with temephos and ... 80 MECHANISMS OF RESISTANCE TO PESTICIDES INSECTICIDE RESISTANCE IN ARTHROPODS Insecticides oPs Carban,~1es - \ Pyrethroids DOT ... one gene for target-site resistance to each insecticide type, and one major gene for metabolic resistance to all insecticides. ...
Monitoring of insecticide resistance in Anopheles sacharovi (Favre 1903) in borderline of Armenia, Naxcivan & Turkey, 2001.. ... Field evaluation of malathion fogging against Japanese encephalitis vector, Culex tritaeniorhynchus. Interestingly enough, not ...
Resistance to neurotoxic insecticides in populations of the coffee leafminer Leucoptera coffeella , IntechOpen, Published on: ... 46] studied the resistance of pyrethroids to Culex pipiens (Diptera: Culicidae) and found different frequencies of resistance ... Spatial dependence of insecticide resistance. To determine the spatial dependence of L. coffeella insecticide resistance, the ... Despite the abamectin insecticide not being among those at risk of resistance in L. coffeella, this insecticide has not been ...
The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the lo... ... Amplification of a serine esterase gene is involved in insecticide resistance in Sri Lankan Culex tritaeniorhynchus. Insect ... Multiple resistance is the resistance to an insecticide through multiple resistance mechanisms. Additional resistance ... Insecticide Resistance Surveillance. The most fundamental feature of insecticide resistance problems may be that each such ...
Insecticide resistance in the mosquito Culex pipiens: What have we learned about adaptation?. M Raymond, C Berticat, M Weill, N ... Insecticide resistance genes induce a mating competition cost in Culex pipiens mosquitoes. C Berticat, G Boquien, M Raymond, C ... Amplification of an esterase gene is responsible for insecticide resistance in a California Culex mosquito. C Mouches, N ... Tracking the evolution of insecticide resistance in the mosquito Culex pipiens. T Lenormand, D Bourguet, T Guillemaud, M ...
1999). Tracking the evolution of insecticide resistance in the mosquito Culex pipiens. Nature 400, 861-864. ... 2012). Association mapping of plant resistance to insects. Trends Plant Sci. 17, 311-319. ... 2011). Exceptional diversity, maintenance of polymorphism, and recent directional selection on the APL1 malaria resistance ... or on physiological mechanisms of susceptibility or resistance to plant compounds, plant varieties or insecticidal molecules ( ...
For instance, rapid evolution of many insecticide resistance genes indicates that the efficacy of insecticides on each Culex ... acts on a wide variety of biological functions in the Culex genome from chromatin organization to insecticide resistance. Table ... 2006 Rapid assay to identify the two genetic forms of Culex (Culex) pipiens L. (Diptera: Culicidae) and hybrid populations. Am ... Multiple adaptive events, involving genes implicated with autogeny, diapause and insecticide resistance were limited to ...
  • Because free-insecticide treated net distribution is planned in Benin (West Africa) during the next few years, we investigated the type, frequency and distribution of insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasciatus mosquitoes in four localities selected on the basis of contrasting agricultural practices, use of insecticides and environment. (lshtm.ac.uk)
  • Molecular and biochemical assays were carried out to identify kdr and Ace.1 mutations in individual mosquitoes and to detect any increase in the activity of enzymes typically involved in insecticide metabolism (oxidase, esterase and glutathion-S-transferases). (lshtm.ac.uk)
  • Mosquitoes Culex pipiens is a major vector species for Japanese encephalitis and filariasis in China, and it is an important vector of West Nile Virus in the USA. (grantome.com)
  • pipiens mosquitoes, and to develop more accurate and cost-effective resistance detection methods that are applicable to field samples. (grantome.com)
  • Here we focus on insecticide resistance at the organism level because mosquitoes may possess compensatory mechanisms under the selection by insecticides. (grantome.com)
  • pipiens pallens mosquitoes, and will lead to novel diagnosis methods for resistance. (grantome.com)
  • We compared Culex quinquefasciatus mosquitoes harbouring two resistance alleles ace-1 R and Kdr R (conferring resistance to carbamate and pyrethroid insecticides, respectively) to mosquitoes bearing only one of the alleles, or neither allele. (biomedcentral.com)
  • In particular, the presence of the Kdr R mutation compensated for the costs of the ace-1 R mutation in an insecticide-free environment, suggesting the strength of selection in untreated areas would be less against mosquitoes resistant to both insecticides than for those resistant to carbamates alone. (biomedcentral.com)
  • Mosquitoes at Ladji had higher oxidase and esterase activity than a laboratory-susceptible strain, but this fact did not seem to contribute to resistance. (cdc.gov)
  • PermaNet 3.0 unwashed deterred 16.84% Culex mosquitoes. (hindawi.com)
  • Many infectious diseases in Africa are caused by Culex mosquitoes [ 10 ] such as West Nile Virus (WVN), Rift Valley Fever (RVF) and Bancroftian filariasis [ 4 ]. (hindawi.com)
  • We tested Anopheles gambiae mosquitoes from Côte d'Ivoire for resistance and screened a subset The Study for target site mutations. (cdc.gov)
  • Mosquitoes were resistant to During May-September 2011, mosquito larvae were insecticides of all approved classes. (cdc.gov)
  • However, these gains are threatened by according to the LIVAK method ( 8 ), and a subsample of the rapid development and spread of insecticide resistance 500 mosquitoes were all found to be the M molecular form among major malaria vectors in Africa ( 3 ). (cdc.gov)
  • Only 4 classes of insecticide, which share thirds of mosquitoes survived the diagnostic dose for 2 modes of action, are approved by the World Health 4 of the 5 insecticides tested (Table 1). (cdc.gov)
  • resistance to DDT and pyrethroids or to organophosphates (Kisumu) mosquitoes to the pyrethroid deltamethrin or and carbamates. (cdc.gov)
  • Whole-genome sequencing reveals high complexity of copy number variation at insecticide resistance loci in malaria mosquitoes. (nih.gov)
  • Indeed, resistance to insecticides has appeared in every major species of arthropod vectors- including mosquitoes, ticks, fleas, lice, and sand flies-and various vectors have developed resistance to every class of pesticide. (nap.edu)
  • However, the mosquitoes that carry the disease soon developed resistance to DDT, and in 1976 WHO shifted its goal from eradication to control. (nap.edu)
  • Amer A, Mehlhorn H (2006a) Repellency effect of forty-one essential oils against Aedes , Anopheles and Culex mosquitoes. (springer.com)
  • Intensive exposure to insecticides has resulted in the evolution of insecticide resistance in the mosquitoes. (bioportfolio.com)
  • israelensis or Lysinibacillus sphaericus in Culex mosquitoes. (ucr.edu)
  • Focal distribution of diflubenzuron resistance mutations in Culex pipiens mosquitoes from Northern Italy. (caa.it)
  • In the Culex pipiens mosquitoes, resistance against diflubenzuron (DFB) was firstly detected in Ravenna (Emilia-Romagna region, Northern Italy), in 2015. (caa.it)
  • Fine-scale spatial and temporal variations in insecticide resistance in Culex pipiens complex mosquitoes in rural south-eastern Tanzania. (harvard.edu)
  • Anopheles funestus group mosquitoes were collected in southern Malawi and the species composition, Plasmodium infection rate, susceptibility to insecticides and molecular bases of the resistance were analysed. (biomedcentral.com)
  • Mosquitoes are one of the organisms subjected to frequent insecticide application due to their status as vectors that carry a wide range of life-threatening diseases. (tubitak.gov.tr)
  • The members of the Culex pipiens complex are the dominant mosquitoes among them. (tubitak.gov.tr)
  • LSTM's Dr Bruno Gomes (http://www.lstmed.ac.uk/about/people/dr-bruno-gomes), the lead author of the paper said: "Mutations in this gene are widely linked with insecticide resistance in mosquitoes and other insects but this is the first record in sandflies. (alphagalileo.org)
  • The two mutations, which are identical to those found in Anopheles and Culex mosquitoes in Africa, co-exist in this species of sandfly in Bihar state, the primary Indian VL focus, and strongly predict survival to DDT and pyrethroids. (alphagalileo.org)
  • Phlebotomine sandflies are very difficult to rear in a laboratory setting, which makes assessment of insecticide resistance using bioassays far more challenging than in mosquitoes, and places a premium on DNA resistance markers which can be applied to any specimen, even those dead and poorly preserved. (alphagalileo.org)
  • Trends in Parasitology February 2011, Vol. 27, No. 2 Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control? (pearltrees.com)
  • A big problem in malaria control is the rapidity with which mosquitoes can develop resistance to insecticides. (royalsocietypublishing.org)
  • Biologists have suggested that effective malaria control, with only weak selection for insecticide resistance, could be achieved if insecticides target only old mosquitoes that have already laid most of their eggs. (royalsocietypublishing.org)
  • We derive, analyse and compare two mathematical models, one for an insecticide that kills on exposure, and the other for an insecticide that targets only older mosquitoes. (royalsocietypublishing.org)
  • Both models predict that insecticide-resistant mosquitoes will become dominant over time but, very importantly, this occurs on a very much slower time scale when the insecticide only affects older mosquitoes. (royalsocietypublishing.org)
  • Numerical simulations show that the effect of targeting only old mosquitoes on the evolution of resistance is dramatic. (royalsocietypublishing.org)
  • because of the potential to slow down or even halt the evolution of insecticide resistance in mosquitoes. (royalsocietypublishing.org)
  • While insecticides are an effective and cheap method of controlling malaria, it is well known that mosquitoes can develop resistance and that this can happen on a surprisingly fast time scale. (royalsocietypublishing.org)
  • propose that the useful lifespan of an insecticide can be enhanced if the insecticide targets only old mosquitoes. (royalsocietypublishing.org)
  • There are two ways in which an insecticide might kill only old mosquitoes and not younger adult mosquitoes. (royalsocietypublishing.org)
  • Such insecticides can uselly be used for fumigation in case of massive outbreaks of mosquitoes as well. (parasitipedia.net)
  • Second, we show that in avian malaria Plasmodium parasites have the ability to increase transmission after being bitten by uninfected Culex mosquitoes. (prolekare.cz)
  • Fotakis EA, Chaskopoulou A, Grigoraki L, Tsiamantas A, Kounadi S, Georgiou L, Vontas J. (2017) Analysis of population structure and insecticide resistance in mosquitoes of the genus Culex, Anopheles and Aedes from different environments of Greece with a history of mosquito borne disease transmission. (forth.gr)
  • In response to this insecticide selection pressure, mosquitoes have evolved several different mechanisms to resist their effect. (ivcc.com)
  • and changes in the metabolic enzymes inside the mosquitoes meaning that insecticides are broken down before they can have their effect. (ivcc.com)
  • In light of widespread insecticide resistance in mosquitoes, however, alternative strategies for reducing transmission by the mosquito vector are urgently needed, including the identification of safe compounds that affect vectorial capacity via mechanisms that differ from fast-acting insecticides. (plos.org)
  • Many mosquitoes of the Culicidae family, such as the mosquitoes of the Culex and Aedes genera, are responsible for the transmission of global diseases such as dengue fever, Zika, chikungunya and West Nile virus fever. (cresa.cat)
  • However, when there is an epidemic outbreak of any of these diseases in a region, zone or city, it may be necessary to apply spray or spray insecticides to eradicate adult mosquitoes in the area and stop or prevent the spread of the disease. (cresa.cat)
  • The applications of these products in an outer zone are only carried out in extreme cases, since insecticides, as well as killing the mosquitoes that interest them, can also affect other species of insects that are beneficial for the environment, they use correctly. (cresa.cat)
  • Currently, the World Health Organization (WHO) allows the use of four types of insecticides to eliminate mosquitoes in case of epidemic outbreaks: pyrethroids (permethrin, deltamethrin and cyhalothrin), carbamates (bendiocarb and propoxur), Organophosphates (pyrimiphos-methyl) and organochlorates (DDT). (cresa.cat)
  • In the case of mosquitoes, the most commonly used insecticides are pyrethroids. (cresa.cat)
  • Currently, the exact doses that make the different species or genera of mosquitoes become resistant to some insecticides are unknown. (cresa.cat)
  • Recently, a study made by researchers from the research line of arbovirus and arthropods of the IRTA-CReSA , the Mosquito Control Service of the Baix Llobregat and the Institute of Global Health (ISGlobal) with international collaboration, has studied the resistance to insecticides of different populations of mosquitoes present in Catalonia. (cresa.cat)
  • During 5 years, researchers have collected samples of mosquitoes from the Culex pipiens , Aedes albopictus and Aedes caspius species, from different parts of Catalonia. (cresa.cat)
  • 1. Harbach RE (1988) The mosquitoes of the subgenus Culex in southwestern Asia and Egypt (Diptera: Culicidae). (ac.ir)
  • Mosquitoes develop impressive resistance mechanisms against many things that are unfavourable to them. (youris.com)
  • Because this bacterium preys on Gram-negative bacteria, our results help to use this bacterium to fight insecticide resistance that caused by the degradation of these chemicals by gram-negative bacteria in the ingestion of these mosquitoes. (iasj.net)
  • Currently, I am characterizing insecticide resistant genes of mosquitoes in aspects of molecular genetics and genomics. (ufl.edu)
  • I would like to compare bacterial communities between preferred and non-preferred habitats by Culex mosquitoes. (ufl.edu)
  • There is more information on the resistance status to malaria vectors compared to Culicines. (biomedcentral.com)
  • For acceptability at community level, nets should as well offer protection to individuals against nuisance vectors such as Culex and Mansonia mosquito species [ 5 , 8 , 9 ]. (hindawi.com)
  • Insecticide resistance in insect vectors of human disease. (ajtmh.org)
  • Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors. (nih.gov)
  • The race is, however, far from over, as emphasized by the emergence of new virulent pathogenic strains, evolution of insecticide-resistant vectors and the adaptations of several pathogenic or competitor species for living in cities. (royalsocietypublishing.org)
  • Here, we present the results of the first genome-wide analysis of population structure and recent natural selection in the Culex pipiens complex, members of which are notorious vectors of West Nile Virus, St. Louise Encephalitis Virus and filariasis worms in the US and worldwide [ 3 - 5 ]. (royalsocietypublishing.org)
  • Toward this goal, insecticides play a major role in controlling major disease vectors-the arthropods that pass pathogens to humans. (nap.edu)
  • The use of insecticides, however, presents a problem parallel to the use of antimicrobials-the chemical agents themselves frequently promote resistance among the vectors they are intended to control. (nap.edu)
  • Research on resistance among vectors now takes two basic approaches. (nap.edu)
  • The second approach to research involves resistance management- that is, developing and implementing control methods that minimize the likelihood that vectors will evolve strong resistance to important insecticides. (nap.edu)
  • The control of filariasis vectors has been enhanced in several areas, but there are main challenges, including increasing resistance to insecticides and lack of cheap and eco-friendly products. (springer.com)
  • Even though chemical vector program has been carried on for long time, these mosquito vectors remain because of repeated use of synthetic products, house hold spray, and insecticides for mosquito control. (hindawi.com)
  • The genera Culex, Aedes and Anopheles are the most important vectors involved in diseases transmission to humans. (thefreelibrary.com)
  • However, these chemical interventions are severely compromised by the development of insecticide resistance in some mosquito vectors and environmental concerns (6-8). (thefreelibrary.com)
  • These results demonstrated that some field strains of Aedes aegypti have developed relatively high resistance to various pyrethroid insecticides, especially fenvalerate, and therefore these insecticides are not recommended to control the vectors of dengue fever in Kaohsiung and Tainan. (ncl.edu.tw)
  • Insecticide resistance is generally considered to undermine control of vector-transmitted diseases because it increases the number of vectors that survive the insecticide treatment. (prolekare.cz)
  • Here, we review evidence that insecticide resistance may have an impact on the quality of vectors and, specifically, on three key determinants of parasite transmission: vector longevity, competence, and behaviour. (prolekare.cz)
  • Insecticide resistance, including resistance to multiple types of insecticides, has arisen in all the insect species that are the major vectors of human diseases ( Table 1 ). (prolekare.cz)
  • 1. Insecticide resistance mechanisms reported to date in natural populations of the main insect vectors of human diseases. (prolekare.cz)
  • 2016. Large-volume gravid traps enhance collection of Culex vectors. (ucr.edu)
  • The findings are of major concern for public health in Italy and Europe, as DFB remains a very important insecticide used for controlling arbovirus mosquito vectors, where alternative larvicides are extremely limited. (caa.it)
  • Malaria vectors have developed resistance to the four families of insecticides available for public health purposes. (biomedcentral.com)
  • The resistance of malaria vectors to insecticide is the main concern in vector control interventions. (biomedcentral.com)
  • Deciphering the dynamics and evolution of insecticide resistance in malaria vectors is crucial for successful vector control. (biomedcentral.com)
  • Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. (re3data.org)
  • Abstract Resistance to pyrethroids, the sole insecticide class recommended for treating bed nets, threatens the control of major malaria vectors, including Anopheles funestus. (pearltrees.com)
  • PLOS 16/12/15 Impact of Insecticide Resistance on the Effectiveness of Pyrethroid-Based Malaria Vectors Control Tools in Benin: Decreased Toxicity and Repellent Effect. (pearltrees.com)
  • PLOS 02/02/17 Genomic Footprints of Selective Sweeps from Metabolic Resistance to Pyrethroids in African Malaria Vectors Are Driven by Scale up of Insecticide-Based Vector Control. (pearltrees.com)
  • Elucidating patterns of genetic structure in malaria vectors to predict the speed and direction of the spread of resistance is essential to get ahead of the 'resistance curve' and to avert a public health catastrophe. (pearltrees.com)
  • Parasites & Vectors (2016) 9:385 Dynamics of pyrethroid resistance in malaria vectors in southern Benin following a large scale implementation of vector control interventions. (pearltrees.com)
  • For this reason, the authors of the study explain that management strategies must be developed taking into account the resistance to insecticides and the possibility that they appear in other species of mosquito disease vectors. (cresa.cat)
  • Background: During the past decade, rapid development of insecticide resistance have been reported among many spe-cies of mosquito vectors against four main categories of insecticides worldwide. (ac.ir)
  • Monitoring of resistance to the pyrethroid cypermetrin in Brazilian Aedes aegypti (Diptera: Culicidae) populations collected between 2001 and 2003. (ajtmh.org)
  • Amer A, Mehlhorn H (2006b) Larvicidal effects of various essential oils against Aedes , Anopheles , and Culex larvae (Diptera, Culicidae). (springer.com)
  • Comparative Bio-Efficacy and Synergism of New Generation Polyfluorobenzyl and Conventional Pyrethroids Against Culex quinquefasciatus (Diptera: Culicidae). (bioportfolio.com)
  • We tested the bio-efficacy of two Culex quinquefasciatus Say (Diptera: Culicidae) laborato. (bioportfolio.com)
  • Oviposition attractancy of dodecanoic, hexadecanoic and tetradecanoic acids against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae). (biomedsearch.com)
  • Larvicidal potential of some plants from west Africa against Culex quinquefasciatus (Say) and anopheles gambiae giles (Diptera: Culicidae). (thefreelibrary.com)
  • In the laboratory, the predation potential of the larvae of A. sulcatus was assessed using the larvae of Culex quinquefasciatus Say 1823 (Diptera: Culicidae) as prey at varying predator and prey densities and available space. (biomedcentral.com)
  • 2. Manimegalai K, Sukanya S (2014) Biolo-gy of the filarial vector, Culex quin-que¬fas¬ciatus (Diptera:Culicidae). (ac.ir)
  • In Brazil, Aedes aegypti resistance to temephos, used since 1967, was detected in several municipalities in 2000. (ajtmh.org)
  • Resistance of Aedes aegypti to organophosphates in several municipalities in the state of Rio de Janeiro and Espírito Santo, Brazil. (ajtmh.org)
  • Aedes aegypti resistance to temephos during 2001 in several municipalities in the States of Rio de Janeiro, Sergipe and Alagoas, Brazil. (ajtmh.org)
  • Quantification methodology for enzyme activity related to insecticide resistance in Aedes aegypti. (ajtmh.org)
  • The objective of this study is to study the resistance development of Aedes aegypti collected from Kaohsiung in 2006 and Tainan in 2007 to frequently used pyrethroid insecticides, and investigate the possible mechanisms involved in resistance development. (ncl.edu.tw)
  • Based on synergist study, the resistance of Chianjen and Per-R42 strains of Aedes aegypti to permethrin, cypermethrin and fenvalerate, is correlated to the degradation of monooxygenase. (ncl.edu.tw)
  • The essential oils (EOs) of Plectranthus amboinicus showed the highest larvicidal activity among four herbal plants studied and β-caryophyllene might be the major component responsible for its differential toxicity to the larvae of Culex quinquefasciatus and Aedes Aegypti . (springer.com)
  • Indeed, it is possible that these insecticides used to Eliminate LF (GPELF) in many African countries can exert indirect selection pressure on mosquito's larvae. (biomedcentral.com)
  • Publications] Kasai, S.: 'P450 monooxygenases are an important mechanism of Permethrin resistance in Culex quinquefasciatus Say larvae. (nii.ac.jp)
  • against the larvae of Culex quinquefasciatus . (hindawi.com)
  • belonging to the family Caesalpiniaceae at various concentrations against the late third instar larvae of Culex quinquefasciatus by following the WHO guidelines. (hindawi.com)
  • The plant species studied were selected on the basis of criteria (Table 1), such as lack of information on activity against Anopheles and Culex larvae, botanical families (Euphorbiaceae, Verbenaceae, and Meliaceae) from which number of larvicidal plant were reported and large distribution in West Africa. (thefreelibrary.com)
  • The bioassay results showed that the larvae collected from different areas of Kaohsiung have developed more than 10-fold resistance to permethrin, cypermethrin, lambda-cyhalothrin, deltamethrin and fenvalerate. (ncl.edu.tw)
  • In particular, the larvae of Chianjen strain had developed 5783-fold resistance to fenvalerate, which is even higher than 3127-fold of Per-R37 strain. (ncl.edu.tw)
  • The larvae of these three strains had developed more than 20-fold resistance to tested insecticides, and the adults had showed less than 31% of mortality after 24-hr exposure to insecticides-impregnated papers. (ncl.edu.tw)
  • 2017. Effects of a larval mosquito biopesticide and Culex larvae on a freshwater nanophytoplankton ( Selenastrum capricornatum ) under axenic conditions. (ucr.edu)
  • Considering the predatory nature of the dytiscid beetles, an assessment of the larvae of Acilius sulcatus Linnaeus 1758 (Coleoptera: Dytiscidae) was made as bio-control agent against the filarial vector Culex quinquefasciatus Say 1823, both under laboratory and field conditions. (biomedcentral.com)
  • The aim of the research was to assess the variation trend of susceptibility levels of Culex quinquefasciatus to two insecticides separately for the field popula-tion compared with subsequent generations of the same sample after multiple colonization.Methods: Larvae and pupae of Cx. (ac.ir)
  • What are the effects of medicinal plants like Ocimum sanctum (tulsi) and Azadirachta indica (neem) extract on the mortality of Culex larvae? (ukessays.com)
  • Also I am interested in the microbial environment of Culex mosquito larvae habitat. (ufl.edu)
  • Presence of insensitive acetylcholinesterase in wild populations of Culex pipiens quinquefasciatus from Benin. (cdc.gov)
  • Seasonal dynamics of insecticide resistance, multiple resistance, and morphometric variation in field populations of Culex pipiens. (semanticscholar.org)
  • have developed resistance against pyrethroids, organochlorine and carbamate. (biomedcentral.com)
  • Due to wide- spread and improper use of insecticides, resistance to pyrethroids is very prevalent in Cx. (grantome.com)
  • One mechanism of resistance to pyrethroids is increased reduction in intrinsic insensitivity of the insect nervous system [ 17 ], and a second mechanism involves increased insecticide metabolism [ 18 ]. (hindawi.com)
  • The target site mutation G119S in the Ace-1 gene ( Ace-1R ) resistance management strategies must reduce the current and L1014F and L1014S kdr mutations were screened by overreliance on pyrethroids. (cdc.gov)
  • The resistance problems continued with the switch to newer insecticides, such as the organophosphates and pyrethroids. (nap.edu)
  • These results indicate the monooxygenase and target site insensitivity might play an important role in resistance developed of Per-R strain to pyrethroids insecticides. (ncl.edu.tw)
  • For example, the kdr mutation is associated with organochlorines and pyrethroids resistance. (biomedcentral.com)
  • Pyrethroids are now being implemented as an alternative in Bihar but because both insecticides attack the same target, the same mutations also compromise the lethality of pyrethroids, at least at lower doses. (alphagalileo.org)
  • We identified a major selective sweep in a genomic region controlling cytochrome P450-based metabolic resistance conferring high resistance to pyrethroids. (pearltrees.com)
  • Such screens can also be impregnated with classical insecticides (e.g. pyrethroids or organophosphates ). (parasitipedia.net)
  • Of the four classes of insecticides available for malaria control, pyrethroids are the only compounds approved for use on long-lasting insecticide-impregnated bed nets (LLINs), due to their relatively low toxicity, and they are heavily used in indoor residual spray (IRS) programs [ 5 ]. (plos.org)
  • The study, published in the PLOS ONE magazine , shows that pyrethroids are the most effective insecticides to eliminate the tiger mosquito , but instead they are not for the common house mosquito ( Culex pipiens ). (cresa.cat)
  • Heightened activities were associated with decreased insecticide susceptibility in HOOD1, THB3, and MINLOVE but not HOOD2. (bioone.org)
  • Finally, naled synergized the toxicity of resmethrin in populations with decreased insecticide susceptibility and increased esterase activity by 2.5- (MINLOVE) to three-fold (THIB). (bioone.org)
  • However, successful implementation of these vector control strategies requires sound knowledge of vector distributions, biology and changing trends on susceptibility status to available insecticide compounds. (biomedcentral.com)
  • and Ace-1R alleles and unprecedentedly high levels of and Hilary Ranson phenotypic resistance to all insecticide classes available for Malaria control depends on mosquito susceptibility to malaria control. (cdc.gov)
  • Susceptibility of field populations of Anopheles gambiae s.l. to organophosphate and carbamate insecticides, Eastern Uganda. (openwetware.org)
  • Either way-and there may be no simple generality-the consequence of the evolution of insecticide resistance for disease ecology deserves additional attention. (prolekare.cz)
  • Dieldrin resistance was present in both species at all four localities. (lshtm.ac.uk)
  • Additional studies with Culex species are recommended to know whether the difference in blood feeding is interspecific (difference in vector behaviour) and not due to intertrial variability. (hindawi.com)
  • Most Culex species rest outdoors, except for C. quinquefasciatus , which is a domestic mosquito, over 50% resting on nonsprayable surfaces in houses, such as mosquito nets, clothes, hangings and furniture [ 13 ]. (hindawi.com)
  • Identifying genetic markers linked to these regulatory alleles is an important next step that would substantially improve insecticide resistance surveillance and population genetic studies in this important vector species. (springer.com)
  • We present the first genome-wide study of recent evolution in Culex pipiens species complex focusing on the genomic extent, functional targets and likely causes of global and local adaptations. (royalsocietypublishing.org)
  • There are over 7740 reported cases of resistance, involving 331 compounds and more than 540 species of insects and mite pests [ 9 ]. (intechopen.com)
  • However, for lack of a better term it is used herein to designate strains of insects that for some reason are able to withstand a larger dose of an insecticide than are other apparently normal insects of the same species. (ufl.edu)
  • There were big differences in the speed of the development of insecticide resistance and the stability of insecticide resistance among insect species and kinds of selected insecticides. (nii.ac.jp)
  • After decades of repeated insecticide use, all of these vector species have demonstrated the capacity to evolve resistance to insecticides. (prolekare.cz)
  • However, the local species composition of this group, their role in malaria transmission, the hybridization between these species, and its impact on the introgression of genes of interests, such as resistance genes, remains largely uncharacterized. (biomedcentral.com)
  • A study led by LSTM identifies a potent molecular mechanism for insecticide resistance in the world's most medically-important sandfly species and develops DNA-diagnostics for monitoring future impact on visceral leishmaniasis control and elimination programs. (alphagalileo.org)
  • Here, using genome-wide transcription and genetic diversity analyses, we show that a shift in the molecular basis of pyrethroid resistance in southern African populations of this species is associated with a restricted gene flow. (pearltrees.com)
  • In some species copy number variation (CNV) of target site loci (e.g. the Ace-1 target site of carbamate insecticides) or detoxification genes has been implicated in the resistance phenotype. (nih.gov)
  • In order to develop field-applicable diagnostics for Vgsc CN, and as a prelude to investigating the possible association of CN with insecticide resistance, three assays were compared for their accuracy in CN estimation in this species. (nih.gov)
  • This study was therefore designed to assess the status of Wuchereria bancrofti infection in Culex quinqefasciatus and Anopheles species after six rounds of MDA in Masasi District, South Eastern Tanzania. (biomedcentral.com)
  • The experiments were done with samples of 100 individuals for each insecticide and species. (cresa.cat)
  • In the case of the common house mosquito, the situation is more complicated, since there are no other effective insecticides for this species. (cresa.cat)
  • additionally, increased HPPD gene expression (target-site based) also contributes to the resistance mechanism in the evolution of herbicide resistance in this naturally occurring weed species. (frontiersin.org)
  • Further analysis confirmed the coincidence of this amino acid substitution with insecticide resistance in several other strains of the same species, and it was also identified in the ace-1 of a resistant strain of A. gambiae . (biomedcentral.com)
  • Consistently high levels of resistance to pyrethroid and carbamate insecticides were recorded and had increased between 2009 and 2014. (biomedcentral.com)
  • Abstract Insecticide resistance in mosquito populations threatens recent successes in malaria prevention. (pearltrees.com)
  • pipiens, characterized novel genes associated with deltamethrin resistance in Cx. (grantome.com)
  • Studying individual genes in cell lines will not reveal resistance at the organismal level because it ignores gene-gene and gene-environment interactions. (grantome.com)
  • The specific aims are: 1) to identify the major candidate genes for resistance to deltamethrin in Cx. (grantome.com)
  • pipiens using transcriptome analysis, 2) to determine the function of the candidate genes in pyrethroid resistance;and 3) to establish association between pyrethroid resistance at organismal level and gene polymorphisms and transcription activity at molecular level. (grantome.com)
  • Metabolic mechanisms of insecticide resistance involving detoxification genes like cytochrome P450 genes, carboxylesterases, and glutathione S-transferases are also important. (springer.com)
  • Multiple adaptive events, involving genes implicated with autogeny, diapause and insecticide resistance were limited to specific populations. (royalsocietypublishing.org)
  • We investigated the hypothesis that observed higher levels of asymmetry displayed by insecticide-resistance genotypes of Lucilia cuprina are restricted to bristle characters, due to the action of resistance genes in bristle cell development, rather than through the disruption of genomic coadaptation. (semanticscholar.org)
  • This change in resistance dynamics is mirrored by prevalent resistance mechanisms, firstly with increased over-expression of key pyrethroid resistance genes ( CYP6Pa / b and CYP6M7 ) in 2014 and secondly, detection of the A296S-RDL dieldrin resistance mutation for the first time. (biomedcentral.com)
  • Genome-wide microarray-based transcription analysis identified overexpression of cytochrome P450 genes as the main mechanism driving this resistance. (pearltrees.com)
  • Heterologous expression of four glutathione transferase genes genetically linked to a major insecticide resistance locus, from the malaria vector Anopheles gambiae. (biomedcentral.com)
  • I have been investigating pesticide resistance and vector competence related genes in local mosquito populations. (ufl.edu)
  • In addition, I worked for DENV genome sequence analysis for investigating differentially expressed genes related to a different vector competence trait to West Nile Virus between two mosquito populations of Culex quinquefasciatus using Illumina RNAseq. (ufl.edu)
  • OBJECTIVE: Vector control is facing a threat due to emergence of resistance to synthetic insecticides. (biomedsearch.com)
  • During the last 10 to 15 years, interest in botanical insecticides has increased to look for substitutions for synthetic insecticides with those based on naturally occurring substances. (ukessays.com)
  • Determination of insecticide resistance and its biochemical mechanisms in 2 strains of Culex quinquefasciatus from Santiago de Cuba]. (cdc.gov)
  • In the diamondback moth, a big difference was found in the sensitivity to sex pheromone between insecticide susceptible and resistant strains. (nii.ac.jp)
  • Wings and bristles: character specificity of the asymmetry phenotype in insecticide-resistant strains of Lucilia cuprina. (semanticscholar.org)
  • The resistance mechanism of permethrin- and deltainethrin-selected high resistant strains (2C1-R and Dec-R) of the house fly Musca domestica vicina was investigated through bioassay, use of different synergists, in vivo test of cuticular penetration and studies on the activities of detoxification enzymes and ATPase. (cnki.com.cn)
  • In the May 8 Nature , Mylene Weill and colleagues at the Institut des Sciences et de l'Evolution , Montpelier, France, identify a mechanism of resistance to organophosphate insecticides, paving the way for a renewed attack on the most common resistant strains ( Nature, 423:136-137, May 8, 2003). (biomedcentral.com)
  • It was discernible that the major resistance mechanism was the MFO-mediated detoxification in the 2C1-R strain and the esterase activity was higher in the Dec-R strain when compared with the NP strain. (cnki.com.cn)
  • It was the latter mechanism of resistance that was the subject of my PhD at the London School of Hygiene & Tropical Medicine during which I purified and characterised esterase enzymes associated with insecticide resistance in populations of the southern house mosquito, Culex quinquefasciatus , from Cuba and South America. (ivcc.com)
  • Because the classic genetic mapping study in our previous studies cannot identify genetic transcripts differentially regulated between susceptible and resistant individuals, this renewal application will use high-throughput transcriptome analysis and population genetic approaches to determine the relationship between pyrethroid resistance at organismal level and transcription activity and gene nucleotide polymorphisms at molecular level. (grantome.com)
  • However in the absence of insecticide pressure, these resistance alleles are often associated with fitness costs that lead to them decreasing in frequency as resistant individuals are out-competed by susceptible rivals. (biomedcentral.com)
  • An early experimental hut trial of ITNs in Côte d'Ivoire demonstrated a survival advantage of homozygotes for kdr resistance ( 8 ), whereas subsequent hut trials in adjacent resistant and susceptible populations showed no apparent difference in the effectiveness of ITNs between the 2 localities ( 9 ). (cdc.gov)
  • To get a clearer understanding of the influence of kdr resistance on the effectiveness of ITN, further experimental hut trials of ITNs against kdr -resistant populations need to be conducted. (cdc.gov)
  • was resistant to tested insecticides (6%-50% mortality). (hindawi.com)
  • We aimed to identify L. coffeella populations resistant to old and new neurotoxic insecticides in regions of Brazil. (intechopen.com)
  • The use of the term "resistant insects" to denote those tolerant to insecticides is probably open to criticism. (ufl.edu)
  • ito & resistant to DDT, and Missiroli (6) told of the failure of DDT to control flies in Italy in 1945-1946 due to their resistance. (ufl.edu)
  • Lindquist and Wilson (56) and Wilson and Gahan (27) have developed a laboratory strain of the house fly, Musca domestica L., that is resistant to DDT and other insecticides. (ufl.edu)
  • Publications] Sarnthoy, O.: 'Cross-resistance of Bacillus thuringiensis resistant population of diamondback moth Plutella xylostella (Lepidoptera : Yponomeutidae). (nii.ac.jp)
  • The presence and distribution of the resistance mutations was highly focal, with a clear pattern of increasing resistant allelic frequencies moving from the Western towards the Eastern provinces of Emilia-Romagna. (caa.it)
  • The very limited insecticide arsenal available (there are still just four classes, only one of which is approved for use on bed nets) is leading to an increasing focus on resistant-management strategies, whereby the useful lifespan of an existing insecticide is enhanced by the way in which the insecticide is used. (royalsocietypublishing.org)
  • Resistant-management strategies may include using different insecticides in space and time and restricting use to specific times and locations. (royalsocietypublishing.org)
  • On one side, you have Whopes directed studies that clearly says that Permanet 3 - and especially Pemanet 3 washed - is not better than P2 on resistant Anopheles and Culex. (malariaworld.org)
  • In fact, it has been shown that the common house mosquito populations in Catalonia are resistant to the four types of insecticides currently permitted. (cresa.cat)
  • In addition, they were strongly resistant to DDT, although this insecticide is not used since the 70s. (cresa.cat)
  • Further evaluation of mesotrione-resistant A. palmeri did not reveal any specific resistance-conferring mutations nor amplification of HPPD gene, the molecular target of mesotrione. (frontiersin.org)
  • compared the sequence of an organophosphate target (the acetylcholinesterase gene ace-1 ) in a resistant and susceptible strain of the mosquito Culex pipiens - vector of the West Nile virus. (biomedcentral.com)
  • If this effect is sufficiently large, the impact of insecticide resistance on disease management may not be as detrimental as previously thought. (prolekare.cz)
  • What is the impact of insecticide resistance on the transmission of vector-borne diseases? (prolekare.cz)
  • Insecticide resistance to organophosphates and carbamates can be the result of changes in acetylcholinesterase activity conferred by the ACE-1 mutation. (cdc.gov)
  • First molecular genotyping of insensitive acetylcholinesterase associated with malathion resistance in Culex quinquefasciatus Say populations in Malaysia. (cdc.gov)
  • Purification, characterization, and kinetic studies of a wild- and an insecticide-insensitive acetylcholinesterase from mosquito (Culex spp. (who.int)
  • an insecticide resistance mechanism called target site resistance. (springer.com)
  • Insecticide resistance present but mechanism unknown or unconfirmed to the best of our knowledge. (prolekare.cz)
  • Ensuring insecticide is sprayed at the correct dose, which has been a focus of LSTM work for several years in Bihar, becomes even more crucial now that sandflies have a demonstrated genetic resistance mechanism. (alphagalileo.org)
  • We have ample evidence on the efficacy of PN3.0 in areas with metabolic-based resistance mechanism. (malariaworld.org)
  • Gene frequency for increased esterases was 0.90, supporting the importance of these enzymes as resistance mechanisms in this strain. (fiocruz.br)
  • The pyrethroid knockdown resistance gene ( kdr ) has become widespread in Anopheles gambiae in West Africa. (cdc.gov)
  • A non-synonymous mutation in the para voltage-gated sodium channel gene reduces pyrethroid-binding affinity, resulting in knockdown resistance ( kdr ). (springer.com)
  • The known insecticide resistance gene CYP6Z1 was differentially expressed exclusively in the context of sublethal permethrin exposure, highlighting the importance of tissue-specificity and environmental conditions in gene expression studies. (springer.com)
  • In a paper (http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005504&rev=1) published in the journal PLOS NTDs, researchers from the Department of Vector Biology of LSTM (UK) and the Rajendra Memorial Research Institute (RMRI, India) identify DNA polymorphisms causing two knockdown resistance (kdr) mutations in the pyrethroid and DDT target site gene of the sandfly Phlebotomus argentipes, the sole vector of VL in India. (alphagalileo.org)
  • PNAS 11/11/16 Restriction to gene flow is associated with changes in the molecular basis of pyrethroid resistance in the malaria vector Anopheles funestus. (pearltrees.com)
  • Insecticide resistance is typically associated with alterations to the insecticidal target-site or with gene expression variation at loci involved in insecticide detoxification. (nih.gov)
  • We show that field-collected Ugandan Culex quinquefasciatus display CNV for the voltage-gated sodium channel gene (Vgsc), target-site of pyrethroid and organochlorine insecticides. (nih.gov)
  • Regarding deltamethrin 0.05%, no significant difference was shown between field strain (58.3%) and 3rd gen-eration (52.7%) compared to the 6th one (33.8%).Conclusion: This finding may reflect the role of the kdr gene in resistance to organochlorine which has cross-re-sistance with pyrethroid insecticides. (ac.ir)
  • Reports of insect resistance began to increase in the 1940s as insecticides and miticides emerged. (intechopen.com)
  • These authors studied insect populations from different locations, using different groups of insecticides with varying mechanisms of action. (intechopen.com)
  • We argue that, in some instances, insecticide resistance is likely to result in a decrease in vector longevity, a decrease in infectiousness, or in a change in behaviour, all of which will reduce the vectorial capacity of the insect. (prolekare.cz)
  • 2016. Oviposition of Culex tarsalis differs on water conditioned by potential fish and insect predators. (ucr.edu)
  • 1995). The control of rice insect pests is mainly depend- and the results confirmed the role of ABC transporter in insecticide ent on the extensive use of chemical insecticides. (deepdyve.com)
  • Some of these insecticides are also known in other areas of insect control, for example in the control of agricultural pests, urban plagues or in humans in the case of lice. (cresa.cat)
  • Resistances occur when a population of insects genetically acquires the ability to tolerate a dose of the product that was originally lethal by the population of the insect. (cresa.cat)
  • The evolutionary dynamics of xenobiotic resistance depends on how resistance mutations influence the fitness of their bearers, both in the presence and absence of xenobiotic selection pressure. (biomedcentral.com)
  • In cases of multiple resistance, these dynamics will also depend on how individual resistance mutations interact with one another, and on the xenobiotics applied against them. (biomedcentral.com)
  • The two insecticides combined in an additive, synergistic and antagonistic manner depending on a mosquito's resistance status, but were not predictable based on the presence/absence of either, or both mutations. (biomedcentral.com)
  • Insecticide resistance mutations interacted to positively or negatively influence a mosquito's fitness, both in the presence or absence of insecticides. (biomedcentral.com)
  • Additional interactions suggest the dynamics of resistance will be difficult to predict in populations where multiple resistance mutations are present or that are subject to treatment by different xenobiotics. (biomedcentral.com)
  • Multiple resistance, where organisms harbour separate mutations conferring resistance against more than one type of xenobiotic, poses an even greater problem. (biomedcentral.com)
  • Southern Côte insecticide resistance have been restricted by the relatively low prevalence of organophosphate/carbamate resistance d'Ivoire and the limited effect that kdr mutations alone have on pyrethroid-based interventions ( 6 ). (cdc.gov)
  • For decades, indoor residual spraying (IRS) targeting sandflies with DDT has been the main control tool in the region and is likely to have selected for the - now widespread - DDT resistance via the kdr mutations detected. (alphagalileo.org)
  • Douris V, Papapostolou KM, Ilias A, Roditakis E, Kounadi S, Riga M, Nauen R, Vontas J. (2017) Investigation of the contribution of RyR target-site mutations in diamide resistance by CRISPR/Cas9 genome modification in Drosophila. (forth.gr)
  • Roditakis E, Mavridis K, Riga M, Vasakis E, Morou E, Rison JL, Vontas J. (2017) Identification and detection of indoxacarb resistance mutations in the para sodium channel of the tomato leafminer, Tuta absoluta. (forth.gr)
  • We want to be ready for resistance mutations to specific repellents. (youris.com)
  • This situation of resistance may seriously jeopardize the efficacy of Insecticide Residual Spray (IRS) and Long-Lasting Insecticide nets ( LLINs ) on which, most African countries including Benin, rely to reduce malaria transmission. (biomedcentral.com)
  • In the latter case, the principal weapon for the control of malaria transmission has been the use of residual insecticides on the interior surfaces of human dwellings. (ciesin.org)
  • Vector control, including indoor residual spraying (IRS) and long-lasting insecticide- treated bed nets (LLINs), is the primary control intervention to prevent malaria transmission. (pearltrees.com)
  • Modeling the impact of these effects on Anopheles population dynamics and Plasmodium transmission predicts that disrupting steroid hormone signaling using 20E agonists would affect malaria transmission to a similar extent as insecticides. (plos.org)
  • Manipulating 20E pathways therefore provides a powerful new approach to tackle malaria transmission by the mosquito vector, particularly in areas affected by the spread of insecticide resistance. (plos.org)
  • When we model the impact of steroid hormone agonists on malaria transmission, we predict that these compounds would provide an important new tool against malaria, particularly in regions of widespread insecticide resistance. (plos.org)
  • The southern house mosquito, Culex quinquefasciatus Say, is a competent vector of human disease and an important target of mosquito abatement programs. (bioone.org)
  • This complex consists of Culex quinquefasciatus (the southern house mosquito) and C. pipiens (the northern house mosquito). (royalsocietypublishing.org)
  • 1) Studies of the risk assessment on the development of insecticide resistance : Laboratory selection of various insecticides by various types o insecticides lead to the development of resistance to the selected insecticides. (nii.ac.jp)
  • worldwide, this method to 1 of 5 insecticides (0.1% bendiocarb, 1.0% fenitrothion, accounts for more than half of malaria control expenditures 0.75% permethrin, 0.05% deltamethrin, 4% DDT) or a ( 1 , 2 ). (cdc.gov)
  • Low levels of resistance were observed for the insecticides chlorantraniliprole (1.02-3.23 times), abamectin (1.19-4.80 times), and deltamethrin (1.05-5.35 times). (intechopen.com)
  • Culex quinquefasciatus , an arboviral and filarial vector, is present year round in several cities of the Republic of Benin. (biomedcentral.com)
  • Thus, the proposed research will greatly enhance the monitoring and management of insecticide resistance. (grantome.com)
  • for recent discussions on the management of insecticide resistance). (royalsocietypublishing.org)
  • Malaria mortality rates in sub-Saharan Africa have declined significantly in recent years as a result of increased insecticide-treated bed net (ITN) usage. (springer.com)
  • Time and mortality curves (LT50) of Brazilian populations of Leucoptera coffeella under the effect of seven insecticides at the recommended doses. (intechopen.com)
  • Those who had a 98 to 100% mortality after 24 hours of being exposed to insecticides were considered susceptible. (cresa.cat)
  • Knockdown and mortality effects of an organophosphate Actellic 300 CS and pyrethroid K-Othrine WG 250 insecticides on the field-collected Culex quinquefasciatus were assessed bimonthly from July to November 2014, using World Health Organization (WHO) cones bioassay test. (readbyqxmd.com)
  • Out of these the major classes of insecticides, the insecticides used in present situation are organophosphates and carbamates. (ukessays.com)
  • 2016. Culex quinquefasciatus larval microbiomes vary with instar and exposure to common wastewater contaminants. (ucr.edu)
  • Bioassays with WHO diagnostic test kits were carried out using pyrethroid, carbarnate, organophosphate and organochlorime insecticides. (lshtm.ac.uk)
  • The bioassays results for three insecticides demonstrated synergism when using PBO and DEF, therefore suggesting that both mixed function oxidase and increased esterases could be acting as resistance mechanisms. (fiocruz.br)
  • 2017. Ovipositional responses of Culex tarsalis to fish-associated semiochemicals in laboratory bioassays. (ucr.edu)
  • But the group writes that there was NO evidence of transmission effect of P3 in areas with metabolic resistance, but still they conclude that here is a new paradigme. (malariaworld.org)
  • 2003). Metabolic re- ABC transporters belong to a large superfamily responsible for sistance and target resistance are the two major mechanisms under- the transport of specific molecules across lipid membranes, in add- lying insecticide resistance. (deepdyve.com)
  • Metabolic resistance relies on ition to insecticide resistance, present in all living organisms (Higgins 1992). (deepdyve.com)
  • Pyrethroid insecticide is currently being promoted worldwide for disease vector control because of their high efficacy, rapid rate of knockdown, and low mammalian toxicity. (grantome.com)
  • It is of particular concern that organophosphate and carbamate resistance associated with the G119S ace - 1 R mutation has recently increased in West Africa in extent and frequency, and is now spreading through the Anopheles gambiae malaria vector population. (biomedcentral.com)
  • Chang CH, MacIntosh D, Lemos B, Zhang Q, Lu C. Characterization of Daily Dietary Intake and the Health Risk of Neonicotinoid Insecticides for the U.S. Population. (harvard.edu)
  • Physiological and Molecular Characterization of Hydroxyphenylpyruvate Dioxygenase (HPPD)-inhibitor Resistance in Palmer Amaranth (Amaranthus palmeri S.Wats. (frontiersin.org)
  • We used the insecticide susceptible laboratory strain "Bleuet" from the University of Montpellier, France, as the reference strain. (fiocruz.br)
  • There seems little doubt therefore that both in the field and in the laboratory there have been developed insects that differ in physiological response to insecticides from other insects that are, as far as can now be shown with one exception, the same morpho- logically. (ufl.edu)
  • and the residual life of this insecticide on different substrates were evaluated under laboratory and field conditions. (biomedcentral.com)
  • The free distribution of Insecticide-Treated Nets (ITN) and the implementation of Indoor Residual Spraying (IRS) as vector control methods against malaria have contributed to the great success of this program. (biomedcentral.com)
  • During the past decade, increased use of insecticide- control paper for 1 hour, according to standard WHO treated bed nets and indoor residual spraying have made procedures ( 7 ). (cdc.gov)
  • The control of mosquito populations with insecticide treated bed nets and indoor residual sprays remains the cornerstone of malaria reduction and elimination programs. (plos.org)
  • The nature and type of local indoor resting wall surfaces to certain level influences the residual bio-efficacy of insecticides used in indoor residual spraying programs. (readbyqxmd.com)
  • o&ce to insecticides by the several insects in an effort to det&crcdne whether sufficient evidence has been presented to warrant a theory as to the cause of this resistance. (ufl.edu)
  • Yet the same compounds had significant repellent action against a wide variety of blood feeding and biting insects, like the Culex mosquito. (youris.com)
  • Prevalence of insecticide resistance in Anopheles multiple insecticide-resistance mechanisms ( 4 ). (cdc.gov)
  • This study reports an increase of resistance intensity and a rise of multiple insecticide resistance in Anopheles funestus in Malawi leading to reduced bed net efficacy. (biomedcentral.com)
  • Furthermore, the 2014 collection exhibited multiple insecticide resistance, notably to DDT, contrary to 2009. (biomedcentral.com)
  • A major threat to further reductions in malaria incidents is the emergence and spread of insecticide resistance (IR) in Anopheles ( An . (springer.com)
  • However, current mosquito control methods are severely threatened by the rapid spread of insecticide resistance in anopheline mosquito populations that transmit the malaria-causing Plasmodium parasites. (plos.org)
  • This is a major limitation, as the increased application of both interventions over the last decade has inevitably led to the emergence and spread of insecticide resistance in natural mosquito populations. (plos.org)
  • pipiens, developed PCR-based knockdown resistance (kdr) mutation detection methods and conducted quantitative trait loci mapping for pyrethroid resistance. (grantome.com)
  • Natural products contain a range of bioactive compounds (6) and related commercial insecticides are commonly perceived as "safe" in comparison to synthetic repellents (10). (thefreelibrary.com)
  • to insecticide-impregnated papers (permethrin 0.75%, delthamethrin 0.05%, DDT 4%, and bendiocarb 0.1%) following WHOPES guidelines. (biomedcentral.com)
  • colony from Mali confirmed the importance of kdr and associated increased permethrin resistance to the CYP9K1 locus on the X chromosome. (springer.com)
  • Yahouédo GA, Chandre F, Rossignol M, Ginibre C, Balabanidou V, Mendez NGA, Pigeon O, Vontas J, Cornelie S. (2017) Contributions of cuticle permeability and enzyme detoxification to pyrethroid resistance in the major malaria vector Anopheles gambiae. (forth.gr)
  • ABC transporters have a modular structure, consist- searching the transcriptome dataset, which may be involved in the ing of two nucleotide-binding domains (NBDs), which bind and insecticide detoxification displayed by these moths. (deepdyve.com)
  • The 2 approaches to malaria prevention, insecticide-treated nets (ITNs) and spraying (IRS), are not mutually exclusive, and in malaria-endemic areas where ITN coverage is still limited, the feasibility of introducing IRS to reduce transmission is being considered, for example, by the President's Initiative Fund ( 4 ). (cdc.gov)
  • Insecticide treated nets are recommended by the World Health Organisation (WHO) for malaria control in malaria endemic countries [ 1 - 3 ] and for control of other diseases of medical importance [ 4 ]. (hindawi.com)
  • New techniques for long-lasting insecticide treatment of nets provide solution for the need to regularly re-treat nets [ 7 ]. (hindawi.com)
  • insecticide-treated bed nets. (cdc.gov)
  • 5. Norris LC, Norris DE (2011) Insecticide resistance in Culex quinquefasciatus mos¬quitoes after the introduction of in¬secticide-treated bed nets in Macha, Zambia. (ac.ir)
  • The next challenge will be to use this molecular understanding to develop novel vector-control methods that avoid or minimize resistance problems. (nap.edu)
  • Vector control, through the use of insecticides, plays a key role in the prevention and control of infectious diseases such as malaria, dengue, and filariasis [1] . (prolekare.cz)
  • Insecticide resistance is a major threat for vector control and prevention of mosquito borne diseases. (caa.it)
  • To fill this knowledge gap and to facilitate the design and implementation of suitable vector control strategies, this study reports an extensive investigation of the dynamic changes in resistance profile and resistance mechanisms associated with ongoing insecticide-based control interventions in Malawi between 2009 and 2014. (biomedcentral.com)
  • 7. Jones CM, Machin C, Mohammed K, Majambere S, Ali AS, Khatib BO, Mcha J, Ranson H, Kelly-Hope LA (2012) In-secticide resistance in Culex quinque-fasciatus from Zanzibar: im¬pli¬ca¬tions for vector control programs. (ac.ir)
  • Université d'Abomey- Calavi (Bénin ) - 2010 - Mémoire en ligne : Tests d'efficacité d'extraits d'huiles végétales sur Anopheles gambiae Giles et Culex quinquefasciatus Say résistants aux pyréthrinoïdes. (pearltrees.com)
  • Indeed, it seems clear that the development of new insecticides will not in itself provide a sustainable solution to the problem of resistance. (royalsocietypublishing.org)
  • The development of new insecticides that can specifically inhibit the G119S mutant form of acetylcholinestease-1 will be crucial in overcoming the spread of resistance," conclude the authors. (biomedcentral.com)
  • At the same time, concerns exist that the world's deadliest animal-the mosquito-is developing resistance to synthetic chemical insecticides, and whether such insecticides have negative effects on humans, animals and the environment. (globe.gov)
  • The long-term goal of this research is to elucidate the genetic and molecular mechanisms of pyrethroid resistance in Cx. (grantome.com)
  • Scientists already have a relatively good understanding of the basic mechanisms underlying resistance to commonly used insecticides, and they are now using recently developed molecular techniques to begin to dissect these mechanisms at the DNA level. (nap.edu)
  • a) Studies on the physiological, biochemical and molecular mechanisms of the development of insecticide resistance. (nii.ac.jp)
  • In order to design more sustainable insecticide resistance management strategies, it is important to investigate the genetic structure of mosquito populations using molecular techniques. (tubitak.gov.tr)