Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Software: Sequential operating programs and data which instruct the functioning of a digital computer.NewsNewspapers: Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster's 3d ed)Mass Media: Instruments or technological means of communication that reach large numbers of people with a common message: press, radio, television, etc.Truth Disclosure: Truthful revelation of information, specifically when the information disclosed is likely to be psychologically painful ("bad news") to the recipient (e.g., revelation to a patient or a patient's family of the patient's DIAGNOSIS or PROGNOSIS) or embarrassing to the teller (e.g., revelation of medical errors).Journalism, Medical: The collection, writing, and editing of current interest material on topics related to biomedicine for presentation through the mass media, including newspapers, magazines, radio, or television, usually for a public audience such as health care consumers.Histamine Release: The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.Television: The transmission and reproduction of transient images of fixed or moving objects. An electronic system of transmitting such images together with sound over a wire or through space by apparatus that converts light and sound into electrical waves and reconverts them into visible light rays and audible sound. (From Webster, 3rd ed)Journalism: The collection, preparation, and distribution of news and related commentary and feature materials through such media as pamphlets, newsletters, newspapers, magazines, radio, motion pictures, television, and books. While originally applied to the reportage of current events in printed form, specifically newspapers, with the advent of radio and television the use of the term has broadened to include all printed and electronic communication dealing with current affairs.Calcium: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.Public Opinion: The attitude of a significant portion of a population toward any given proposition, based upon a measurable amount of factual evidence, and involving some degree of reflection, analysis, and reasoning.Delayed-Action Preparations: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.Communications Media: The means of interchanging or transmitting and receiving information. Historically the media were written: books, journals, newspapers, and other publications; in the modern age the media include, in addition, radio, television, computers, and information networks.Ryanodine Receptor Calcium Release Channel: A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.Cells, Cultured: Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.Neurotransmitter Agents: Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Communication: The exchange or transmission of ideas, attitudes, or beliefs between individuals or groups.Radio: The transmission and reception of electric impulses or signals by means of electric waves without a connecting wire, or the use of these waves for the wireless transmission of electric impulses into which sound is converted. (From Webster's 3d)Kinetics: The rate dynamics in chemical or physical systems.Virus Release: Release of a virus from the host cell following VIRUS ASSEMBLY and maturation. Egress can occur by host cell lysis, EXOCYTOSIS, or budding through the plasma membrane.Health Communication: The transfer of information from experts in the medical and public health fields to patients and the public. The study and use of communication strategies to inform and influence individual and community decisions that enhance health.Bibliometrics: The use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Formerly called statistical bibliography. (from The ALA Glossary of Library and Information Science, 1983)Rats, Sprague-Dawley: A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.Dose-Response Relationship, Drug: The relationship between the dose of an administered drug and the response of the organism to the drug.Information Dissemination: The circulation or wide dispersal of information.Physician-Patient Relations: The interactions between physician and patient.Acetylcholine: A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.Calcium Signaling: Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.Adenosine Triphosphate: An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.Electric Stimulation: Use of electric potential or currents to elicit biological responses.Synaptic Transmission: The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.Public Relations: Relations of an individual, association, organization, hospital, or corporation with the publics which it must take into consideration in carrying out its functions. Publics may include consumers, patients, pressure groups, departments, etc.Rats, Wistar: A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.Calcium Channels: Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.Exocytosis: Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.Norepinephrine: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.Sarcoplasmic Reticulum: A network of tubules and sacs in the cytoplasm of SKELETAL MUSCLE FIBERS that assist with muscle contraction and relaxation by releasing and storing calcium ions.Glutamic Acid: A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM.Presynaptic Terminals: The distal terminations of axons which are specialized for the release of neurotransmitters. Also included are varicosities along the course of axons which have similar specializations and also release transmitters. Presynaptic terminals in both the central and peripheral nervous systems are included.Role Playing: The adopting or performing the role of another significant individual in order to gain insight into the behavior of that person.Rabbits: The species Oryctolagus cuniculus, in the family Leporidae, order LAGOMORPHA. Rabbits are born in burrows, furless, and with eyes and ears closed. In contrast with HARES, rabbits have 22 chromosome pairs.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Dopamine: One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.Information Science: The field of knowledge, theory, and technology dealing with the collection of facts and figures, and the processes and methods involved in their manipulation, storage, dissemination, publication, and retrieval. It includes the fields of COMMUNICATION; PUBLISHING; LIBRARY SCIENCE; and informatics.Advertising as Topic: The act or practice of calling public attention to a product, service, need, etc., especially by paid announcements in newspapers, magazines, on radio, or on television. (Random House Unabridged Dictionary, 2d ed)Chemistry, Pharmaceutical: Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.Nitric Oxide: A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.Synaptic Vesicles: Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.Arachidonic Acid: An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.Parental Notification: Reporting to parents or guardians about care to be provided to a minor (MINORS).United StatesMicrodialysis: A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.Membrane Potentials: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).Inositol 1,4,5-Trisphosphate: Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.Ryanodine: A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.Neurons: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.Tobacco Industry: The aggregate business enterprise of agriculture, manufacture, and distribution related to tobacco and tobacco-derived products.Persuasive Communication: A mode of communication concerned with inducing or urging the adoption of certain beliefs, theories, or lines of action by others.Enzyme Inhibitors: Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.Serotonin: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.Inositol 1,4,5-Trisphosphate Receptors: Intracellular receptors that bind to INOSITOL 1,4,5-TRISPHOSPHATE and play an important role in its intracellular signaling. Inositol 1,4,5-trisphosphate receptors are calcium channels that release CALCIUM in response to increased levels of inositol 1,4,5-trisphosphate in the CYTOPLASM.Drug Compounding: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)Consumer Advocacy: The promotion and support of consumers' rights and interests.Secretory Rate: The amount of a substance secreted by cells or by a specific organ or organism over a given period of time; usually applies to those substances which are formed by glandular tissues and are released by them into biological fluids, e.g., secretory rate of corticosteroids by the adrenal cortex, secretory rate of gastric acid by the gastric mucosa.Publishing: "The business or profession of the commercial production and issuance of literature" (Webster's 3d). It includes the publisher, publication processes, editing and editors. Production may be by conventional printing methods or by electronic publishing.Guinea Pigs: A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.Drug Carriers: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Potassium: An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.Medical Tourism: Travel to another country for the purpose of medical treatment.Synapses: Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.Consumer Health Information: Information intended for potential users of medical and healthcare services. There is an emphasis on self-care and preventive approaches as well as information for community-wide dissemination and use.Cytochromes c: Cytochromes of the c type that are found in eukaryotic MITOCHONDRIA. They serve as redox intermediates that accept electrons from MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III and transfer them to MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX IV.Humanism: An ethical system which emphasizes human values and the personal worth of each individual, as well as concern for the dignity and freedom of humankind.Calcimycin: An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.Solubility: The ability of a substance to be dissolved, i.e. to form a solution with another substance. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Egtazic Acid: A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.Terminally Ill: Persons with an incurable or irreversible illness at the end stage that will result in death within a short time. (From O'Leary et al., Lexikon: Dictionary of Health Care Terms, Organizations, and Acronyms for the Era of Reform, 1994, p780)Neuromuscular Junction: The synapse between a neuron and a muscle.Tablets: Solid dosage forms, of varying weight, size, and shape, which may be molded or compressed, and which contain a medicinal substance in pure or diluted form. (Dorland, 28th ed)Public Policy: A course or method of action selected, usually by a government, from among alternatives to guide and determine present and future decisions.Health Education: Education that increases the awareness and favorably influences the attitudes and knowledge relating to the improvement of health on a personal or community basis.gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.Rats, Inbred Strains: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding.Mitochondria: Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed)Hydrogen-Ion Concentration: The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Patch-Clamp Techniques: An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.Nerve Endings: Branch-like terminations of NERVE FIBERS, sensory or motor NEURONS. Endings of sensory neurons are the beginnings of afferent pathway to the CENTRAL NERVOUS SYSTEM. Endings of motor neurons are the terminals of axons at the muscle cells. Nerve endings which release neurotransmitters are called PRESYNAPTIC TERMINALS.Mast Cells: Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Arachidonic AcidsCytosol: Intracellular fluid from the cytoplasm after removal of ORGANELLES and other insoluble cytoplasmic components.Cell Membrane: The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells.Neutrophils: Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.Calcium Channel Blockers: A class of drugs that act by selective inhibition of calcium influx through cellular membranes.Social Conditions: The state of society as it exists or in flux. While it usually refers to society as a whole in a specified geographical or political region, it is applicable also to restricted strata of a society.Public Health: Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.Drug Delivery Systems: Systems for the delivery of drugs to target sites of pharmacological actions. Technologies employed include those concerning drug preparation, route of administration, site targeting, metabolism, and toxicity.Cattle: Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor.Phospholipases A: Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates.Stimulation, Chemical: The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.Apoptosis: One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.Perfusion: Treatment process involving the injection of fluid into an organ or tissue.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Phospholipases A2: Phospholipases that hydrolyze the acyl group attached to the 2-position of PHOSPHOGLYCERIDES.Enzyme Activation: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.Australia: The smallest continent and an independent country, comprising six states and two territories. Its capital is Canberra.Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Investments: Use for articles on the investing of funds for income or profit.Methylcellulose: Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.Cytochrome c Group: A group of cytochromes with covalent thioether linkages between either or both of the vinyl side chains of protoheme and the protein. (Enzyme Nomenclature, 1992, p539)Dinoprostone: The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.Electrophysiology: The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.Excitatory Postsynaptic Potentials: Depolarization of membrane potentials at the SYNAPTIC MEMBRANES of target neurons during neurotransmission. Excitatory postsynaptic potentials can singly or in summation reach the trigger threshold for ACTION POTENTIALS.Catecholamines: A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.L-Lactate Dehydrogenase: A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.Excipients: Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.Grief: Normal, appropriate sorrowful response to an immediate cause. It is self-limiting and gradually subsides within a reasonable time.Tetrodotoxin: An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.Glucose: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.Lipopolysaccharides: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)Technology, Pharmaceutical: The application of scientific knowledge or technology to pharmacy and the pharmaceutical industry. It includes methods, techniques, and instrumentation in the manufacture, preparation, compounding, dispensing, packaging, and storing of drugs and other preparations used in diagnostic and determinative procedures, and in the treatment of patients.Mice, Inbred C57BLAction Potentials: Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.Extracellular Space: Interstitial space between cells, occupied by INTERSTITIAL FLUID as well as amorphous and fibrous substances. For organisms with a CELL WALL, the extracellular space includes everything outside of the CELL MEMBRANE including the PERIPLASM and the cell wall.Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).Professional-Family Relations: The interactions between the professional person and the family.Terrorism: The use or threatened use of force or violence against persons or property in violation of criminal laws for purposes of intimidation, coercion, or ransom, in support of political or social objectives.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.Cyclic AMP: An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.Chelating Agents: Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.Ruthenium Red: An inorganic dye used in microscopy for differential staining and as a diagnostic reagent. In research this compound is used to study changes in cytoplasmic concentrations of calcium. Ruthenium red inhibits calcium transport through membrane channels.Information Services: Organized services to provide information on any questions an individual might have using databases and other sources. (From Random House Unabridged Dictionary, 2d ed)Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Editorial Policies: The guidelines and policy statements set forth by the editor(s) or editorial board of a publication.Medical Oncology: A subspecialty of internal medicine concerned with the study of neoplasms.Islets of Langerhans: Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.Cell Membrane Permeability: A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.Polyglycolic Acid: A biocompatible polymer used as a surgical suture material.Particle Size: Relating to the size of solids.Adenosine: A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.Prostaglandins: A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes.Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits the enzyme cyclooxygenase necessary for the formation of prostaglandins and other autacoids. It also inhibits the motility of polymorphonuclear leukocytes.Homicide: The killing of one person by another.Hippocampus: A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation.Potassium Chloride: A white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.Substance P: An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses.Endothelium, Vascular: Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.Magnesium: A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.Polymers: Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).Thapsigargin: A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM.Peptides: Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.Dogs: The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)Microscopy, Confocal: A light microscopic technique in which only a small spot is illuminated and observed at a time. An image is constructed through point-by-point scanning of the field in this manner. Light sources may be conventional or laser, and fluorescence or transmitted observations are possible.Receptors, Presynaptic: Neurotransmitter receptors located on or near presynaptic terminals or varicosities. Presynaptic receptors which bind transmitter molecules released by the terminal itself are termed AUTORECEPTORS.Gonadotropin-Releasing Hormone: A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.Membrane Proteins: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.Basophils: Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes.Recombinant Proteins: Proteins prepared by recombinant DNA technology.Fluorescent Dyes: Agents that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.Microspheres: Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.Blood Platelets: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.Oxytocin: A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.TritiumCorpus Striatum: Striped GRAY MATTER and WHITE MATTER consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the THALAMUS in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The WHITE MATTER is the INTERNAL CAPSULE.Interleukin-1: A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.Bradykinin: A nonapeptide messenger that is enzymatically produced from KALLIDIN in the blood where it is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Bradykinin is also released from MAST CELLS during asthma attacks, from gut walls as a gastrointestinal vasodilator, from damaged tissues as a pain signal, and may be a neurotransmitter.Attitude to Health: Public attitudes toward health, disease, and the medical care system.Caspases: A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.Taxes: Governmental levies on property, inheritance, gifts, etc.Macrophages: The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)Mice, Knockout: Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes.Planning Techniques: Procedures, strategies, and theories of planning.Interleukin-8: A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.Hydrolysis: The process of cleaving a chemical compound by the addition of a molecule of water.Cell Degranulation: The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.Cytokines: Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.Myocardium: The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.Pituitary Gland, Anterior: The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION.New South Wales: A state in southeastern Australia. Its capital is Sydney. It was discovered by Captain Cook in 1770 and first settled at Botany Bay by marines and convicts in 1788. It was named by Captain Cook who thought its coastline resembled that of South Wales. (From Webster's New Geographical Dictionary, 1988, p840 & Room, Brewer's Dictionary of Names, 1992, p377)Adenosine Diphosphate: Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.Osmolar Concentration: The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent.Radioimmunoassay: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.Blotting, Western: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.Protein Kinase C: An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.Secretory Vesicles: Vesicles derived from the GOLGI APPARATUS containing material to be released at the cell surface.Carrier Proteins: Transport proteins that carry specific substances in the blood or across cell membranes.Anthropology, Cultural: It is the study of social phenomena which characterize the learned, shared, and transmitted social activities of particular ethnic groups with focus on the causes, consequences, and complexities of human social and cultural variability.Peptide Termination Factors: Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRANSLATIONAL) on RIBOSOMES. They include codon-specific class-I release factors, which recognize stop signals (TERMINATOR CODON) in the MESSENGER RNA; and codon-nonspecific class-II release factors.Cell Survival: The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.Biological Transport: The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments.Education: Acquisition of knowledge as a result of instruction in a formal course of study.Commerce: The interchange of goods or commodities, especially on a large scale, between different countries or between populations within the same country. It includes trade (the buying, selling, or exchanging of commodities, whether wholesale or retail) and business (the purchase and sale of goods to make a profit). (From Random House Unabridged Dictionary, 2d ed, p411, p2005 & p283)Hospices: Facilities or services which are especially devoted to providing palliative and supportive care to the patient with a terminal illness and to the patient's family.
"Media Centre > News > release". Xstrata. Retrieved 19 April 2011. "Xstrata wins Falconbridge battle". BBC News. 15 August 2006 ... "Xstrata to buy Australian rival". BBC News. 7 April 2003. Retrieved 19 April 2011. "BHP trumps Xstrata's WMC bid". Australia: ...
News release. April 9, 2013. Retrieved July 10, 2013. ... which will be labelled as ANSI/TIA-942-B is slated for release ...
"News Release". www.edah.org. Retrieved 2017-08-30. Berman, Rabbi Saul J. "The Emergence, Role, and Closing of Edah , The Jewish ... In a news release, leaders of the organization acknowledged that it had made significant achievements, but given limited ...
"Panasas Accelerates pNFS Adoption". News release. Panasas. May 23, 2007. Retrieved July 19, 2013. "Panasas ActiveStor 14 ...
"IOCELL Networks Purchases Innovative NDAS Technology". News release. IOCELL. August 4, 2011. Retrieved June 1, 2013. "Network ...
"Intel Refreshes Ultimate Enthusiast Processor Lineup with Six-Core Offerings". News release. Intel. November 14, 2011. ... Intel X79 SATA AHCI RAID Mode Notice Archived 2014-03-26 at Archive.is Official Release Date and Ivy Bridge vs Sandy Bridge ... The X79 chipset does not support installing Windows XP in AHCI mode for Intel's Serial ATA controllers as Intel won't release ...
News Release. County of Los Angeles. 19 October 2010. Retrieved 23 October 2012. "Minutes" (PDF). Clerk of the Board of ... U.S. News & World Report. 2013. Retrieved 23 September 2013. "Rancho Ranked California's Top Rehabilitation Hospital in Annual ... U.S. News & World Report. 2013. Retrieved 23 September 2013. "Rancho Los Amigos National Rehabilitation Center". Best Hospitals ... News & World Report's America's Best Hospitals: Harbor-UCLA Medical Center was ranked #26 in the Los Angeles metropolitan area ...
Radware "Nortel Networks Completes Acquisition of Alteon WebSystems". News release. Nortel. October 5, 2000. Archived from the ... News release. Nortel. July 28, 2000. Retrieved June 8, 2011. Phil Hochmuth (July 30, 2001). "Nortel's Alteon play gets mixed ... "Alteon Networks and Network Appliance Demonstrate Gigabit Ethernet Connectivity at NetWorld+Interop Atlanta". Press release. ... Press release. October 14, 1996. Archived from the original on January 13, 1997. Retrieved August 27, 2013. Jeff Caruso ( ...
"ABORIGINAL ARTISTS RECEIVE LIFETIME ACHIEVEMENT AWARDS". news release. BC Achievement Foundation. Retrieved 14 September 2013 ... news release. Canada Council for the Arts. Retrieved 14 September 2013. "Honorary degree recipients". University of Victoria. ... "Haida artist Davidson wins B.C.'s Audain Prize". CBC News. Retrieved 2017-03-21. "Robert Davidson, Eagle of the Dawn Artist Ltd ... ISBN 0-295-97259-9. Robert Davidson lands lifetime achievement award By Alex Browne, Arts Reporter, Peace Arch News, 12 June ...
News Release, . (24 July 2013). "Liverpool School of Tropical Medicine Becomes Higher Education Institution". Liverpool School ... Having received news that the RSH greatly appreciated the collection of the hospital's 'tropical' cases into one centre rather ...
News Release. Athens, Georgia: University of Georgia Office of Public Affairs News Service. Retrieved 2008-02-07. Odum School ...
"New Armed Forces Institute of Regenerative Medicine to Lead Way in Caring for Wounded". News Release. U.S. Department of ...
"News release - Federal and provincial governments celebrate the completion of upgrades to Trans-Canada Highway in Saskatchewan ... News Release >. Government of Canada. Archived from the original on February 18, 2008. Retrieved 2009-02-09. Hall, Angela ( ... "Canada News Centre - Federal and provincial governments celebrate the completion of upgrades to Trans-Canada Highway in ...
News Release. Business Wire. Retrieved 22 September 2012. "Opsware Targets BMC and CA". Technology News. Red Orbit. Retrieved ... "Commission clears joint venture @Home Benelux B.V". Press Releases. Europa.eu. Retrieved 22 September 2012. Grice, Corey (11 ... "John O'Farrell Joins Silver Spring Network As Executive Vice President of Business Development". News & Events. Silver Spring ... Home Expands Abroad". Internet News. InternetNews.com. June 19, 2000. Retrieved 22 September 2012. McBride, Sarah. "Andreessen ...
"News Release". Juno Therapeutics. "News Release". Juno Therapeutics. Lombardo, Cara (2018-01-22). "Celgene to Buy Juno ... "News Release". Juno Therapeutics. "MedImmune, Juno Team Up to Study Cancer Immunotherapy Combo". GEN. "Juno Therapeutics Buys ... Biotechnology News. Retrieved 2016-02-11. "Juno Therapeutics Acquires X-Body for $44M+". GEN. "Celgene Launches $1B ...
... news release, June 24, 2009. News Release.>HHS Secretary Sebelius Welcomes Deputy Secretary Bill Corr, Indian Health Service ...
"Three Finalists Selected for MSU President's Position." Press release. MSU News Service. September 9, 2009. Accessed 2013-08-26 ... "Carnegie Recognizes MSU Excellence." Press release. MSU News. January 12, 2011. Accessed 2012-09-27. Schontzler, Gail. "MSU's ... Las Cruces Sun-News. May 7, 2009. "NMSU Provost Offered Montana State's Top Job." Albuquerque Journal. October 14, 2009. ... Tracy Ellig, the number two person in the communications division and director of MSU's news service, was named interim ...
"News Release." United Media: United Feature Syndicate: Newspaper Enterprise Association, 17 July. Grimes, Mary Ann. "News ... "MaryJane Butters is expanding to her first retail branch." Moscow-Pullman Daily News, 23 Aug. 2008. Spurling, Carol. "MaryJane ... Traditional American Farming Techniques, Amazon.com "MaryJane Writes Forewords for Three Great New Books." News from the Book ... "Community Supported Agriculture." Moscow Food Co-Op News, Mar. 2007. Roberts, Tara. "Farm fantasy: Area families get their fill ...
Press Release Newswire, October 8, 2006 The Salem News, Vendors: ITV No Longer in Business, Cate Lecuyer, October 3, 2008 ... Arena Sports Network Announces Airing of Fusion Power Hour Warning Letter, April 19, 2004 Federal Trade Commission news release ... News Release. Federal Trade Commission. November 21, 2007. United States District Court, Northern District of Illinois, Eastern ... The Salem News, July 19, 2008 Infomercial creator pleads guilty, will get year for tax fraud, The Salem News, May 3, 2011 "' ...
News release. Archived from the original on 2011-07-06. Retrieved 200-10-13. Check date values in: ,access-date= (help) Farr, ... 2012 Flock, T. s. "Bratsa Bonifacho: SKALAMERIJA at Foster/White." Seattle Arts News, 2012 Bonifacho: Retrospective: 1973 - ...
News Release. Washington State Secretary of State. Retrieved December 7, 2012. Mapes, Jeff (December 6, 2012). "Same-sex ... The News-Tribune. Retrieved September 18, 2012. Editorial Board (September 16, 2012). "Affirm R-74 because state has no role in ... Official Press Release (December 5, 2012). "Gov. Gregoire and Secretary Reed certify Referendum 74". Governor of Washington. ... Other endorsements included the Tacoma News-Tribune, Spokane's The Spokesman-Review, Vancouver's The Columbian, Yakima Herald- ...
News Release. The Peregrine Fund (2012-08-23). Retrieved on 2013-07-28. Tower of Silence, Karachi Quintana-Murci, Lluís; Chaix ... Parsis - a photographic journey-online book "Falling Indian minority hopes romance can stop decline"-BBC News. ...
External link in ,publisher= (help); Missing or empty ,url= (help) "News Release". "News Release". "News Release". "AMP ... NASA 360 won the Emmy for non-news program editing from the National Capital Chesapeake Bay Chapter of the National Academy of ...
News Release. Athens, Georgia: University of Georgia Office of Public Affairs News Service. Retrieved 2008-02-07. "Owens ... "DesignIntelligence Releases List of Top Landscape Architecture Schools". LAND online: landscape architecture news digest. ... "Survey of Best LA Schools Released". LAND online: landscape architecture news digest. American Society of Landscape Architects ...
... news_c.shtml, 9 Aug 2005, 11:35 AM. Accessed 30 May 2006. State of Tennessee, Department of Corrections. News Release. "Inmate ... Silence, Michael, "Breaking News: Courthouse Shooting," Knox News [online version of Knoxville News Sentinel] http://blogs. ... Fox News Capture Story CNN Capture Story MSNBC Coverage. ... www.wbir.com/news/archive.aspx?storyid=34291, 13 May 2006, 11: ... Knoxville News Sentinel CNN.com . "Courthouse Shooting Leaves Officer Dead." CNN transcript, draft [?]. Tony Harris, host. http ...
"Daily News. Retrieved March 13, 2010.. *^ "CW's Melrose Place Canceled - Ratings". TVbytheNumbers. May 19, 2010. Retrieved ... "Network TV Press Releases". TV by the Numbers. Retrieved November 7, 2013 ... Alyssa.com - NEWS: Romantically Challenged, Alyssa Milano, September 14, 2009 *^ CBS 2009 Fall Preview "Archived copy". ... "Breaking News - CBS Confirms Six Newcomers - TheFutonCritic.com".. *^ "CBS Announces 2009-2010 Schedule - Ratings". ...
Last week Presidential candidate Mitt Romney released his tax returns, and the news channels were abuzz with commentary about ... Typical was a person interviewed in a news report who stated "I pay 28% in taxes and have trouble every month making my rent." ... Leave a Comment / News / By Lonnie Chrisman / 01/30/2012 03/12/2020 ...
Distributing Press Releases, Crisis PR Management, Crafting Your Public Relations Strategy, In-house vs. Out-source, and How to ... Distributing press releases can be a useful marketing activity simply because it allows you to get all the latest news about ... Thanksgiving Day 2010 is coming, so lets the hot news about Thanksgiving Day 2010. 1. Thanksgiving Dinner . (Public Relations ... Distributing Press Releases, Crisis PR Management, Crafting Your Public Relations Strategy, In-house vs. Out-source, and How to ...
More on this News Release. Want to exercise more? Get yourself some competition. University of Pennsylvania ... Trending News Releases. * How flowers adapt to their pollinators University of Vienna ... Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing ... EurekAlert! offers eligible public information officers paid access to a reliable news release distribution service. ...
HTML version of the entire news release The PDF version of the news release Table of Contents Last Modified Date: April 19, ... For further information, see the Technical Note in this news release. Families and Unemployment The number of families with at ... Data in this release are annual averages. Families are classified either as married- couple families or as families maintained ... For release 10:00 a.m. (EDT) Thursday, April 19, 2018 USDL-18-0589 Technical information: (202) 691-6378 * [email protected] * ...
News Releases 2018». *Fighting cancer. UTA startup AbeXXa Biologics, reimagining cancer immunotherapy with global ...
An immunotherapy drug embedded in a slow-release hydrogel invented at Rice in collaboration with the University of Texas Health ... Rice News Archives. Rice News Archives. Select Month. January 2019 December 2018 November 2018 October 2018 September 2018 ... The lab tested more common hydrogels but found that they were unable to provide the same controlled release and also failed to ... "The MDP hydrogel provides a unique environment for the release of CDN that other gels just cant match," Hartgerink said. ...
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... are published each month in the Employment Situation news release. - 6 - Technical Note This news release presents statistics ... See box note in the BLS news release USDL 07-0486, "The Employment Situation: March 2007," issued on April 6, 2007, for a ... Employment Situation News Release. Technical information: Household data: (202) 691-6378 USDL 08-0448 http://www.bls.gov/cps/ ... Updated population controls are introduced annually with the release of January data. HOUSEHOLD DATA HOUSEHOLD DATA Table A-3. ...
A video news release (VNR) is a video segment made to look like a news report, but is instead created by a PR firm, advertising ... Video press releases at prREACH "Office of National Drug Control Policy--Video News Release, B-303495, January 4, 2005"} New ... Fake news Infoganda Journalism ethics and standards News propaganda Farsetta, Diane (March 16, 2006). "Fake TV News: Widespread ... May 19, 2004 GAO decision B-304228, "Department of Education--No Child Left Behind Act Video News Release and Media Analysis". ...
Following the release of results, Douglas Bryant. , president and chief executive officer, and Randy Steward. , chief financial ... View source version on businesswire.com: http://www.businesswire.com/news/home/20180207006361/en/ ...
U.S. Department of Labor releases are accessible on the Internet at www.dol.gov. The information in this news release will be ... Please specify which news release when placing your request at (202) 693-7828 or TTY (202) 693-7755. The Labor Department is ... Release Number: 13-40-ATL (35) San-Way Farms Inc. in Florida pays nearly $90,000 in back wages and penalties for violations ... Press Releases. U.S. Department of Labor. Wage and Hour Division. ...
This news release provides the latest developments in the prevention and treatment of HIV and related infectious diseases ... CDC also released a new model of the impact of expanding the reach of key HIV prevention strategies, including testing, ... Press Releases: *Gay and Bisexual Men of Color Face Greatest Risk of HIV ...
This news release highlights new data trends in HIV care by race in observance on National Black HIV/AIDS Awareness Day 2016. ... Press Release: Despite progress, persistent disparities contribute to the HIV burden among African Americans ...
... www.prnewswire.com/news-releases/cti-biopharma-reports-third-quarter-2017-financial-results-300550215.html ... This press release includes forward-looking statements within the meaning of the Safe Harbor provisions of the Private ... has provided in this press release the historical non-GAAP financial measure of operating loss, excluding non-cash share-based ... does not intend to update any of the statements in this press release upon further developments. ...
... Transmission of material in this release is embargoed until USDL-15-0610 8:30 a.m. (EDT), Friday, ... Real Earnings for April 2015 is scheduled to be released on Friday, May 22, 2015 at 8:30 a.m. (EDT). Table A-1. Current and ... Information in this release will be made available to sensory impaired individuals upon request. Voice phone: 202-691-5200; TDD ... There are several characteristics of the series presented in this release that limit their suitability for some types of ...
... Transmission of material in this release is embargoed until USDL-10-1282 8:30 a.m. (EDT), Friday, ... Real Earnings for September 2010 is scheduled to be released on Friday, October 15, 2010 at 8:30 a.m. (EDT). Table A-1. Current ... Information in this release will be made available to sensory impaired individuals upon request. Voice phone: 202-691-5200; TDD ... There are several characteristics of the series presented in this release that limit their suitability for some types of ...
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"In the News" News Releases Publications News&Views WeeklyAt the Forefront Subscribe Brochures & Reports ... Core proteins orchestrate the assembly and release of the infectious virus, as well as the disassembly of viral particles upon ...
The names of the deceased will be withheld for 24 hours pending release by the U.S. Department of Defense. All families have ...
Topics of discussion include the state of HIV research during the past year and newly released research. ... Current News Releases. 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 ...
NEWS RELEASE Trimble Adds Lean Scheduling to Building Construction Portfolio. Cloud-Based LeanSight Production Management ... Print News , Send Link Trimble Inc.. 935 Stewart Drive. Post Office Box 3642. Sunnyvale, CA 94085. 1.408.481.8000 phone. 1.408. ...
News Release. Archive - New Contact Information. For more information about this archival news release, please contact ... www.niehs.nih.gov/news/newsroom/newslist/index.cfm) ) to stay current on NIEHS news, press releases, grant opportunities, ... News Releases. Table of Contents *New Scientific Review of Saccharin to Be Discussed As Board Reviews Proposed Listings for 9th ... Previous Release. NIH Symposium to Outline and Discuss Environmental Genome to Study Chemical Susceptibility ...
News Release. Archive - New Contact Information. For more information about this archival news release, please contact ... www.niehs.nih.gov/news/newsroom/newslist/index.cfm) ) to stay current on NIEHS news, press releases, grant opportunities, ... News Releases. Table of Contents *New Research Outlines Public Health Consequences of World Trade Center Disaster ... Previous Release. Four New Research Centers to Explore Link between Oceans and Human Health ...
  • Creating Publicity, Working With Public Relation Agencies, Creating Buzz, How to Make Your Company Story Newsworthy, Writing & Distributing Press Releases, Crisis PR Management, Crafting Your Public Relations Strategy, In-house vs. Out-source, and How to Get More Out of Your PR Strategy. (articleslash.net)
  • The number of unhealthy air days in nearly three dozen cities soared in the first two years of the Trump administration, according to an annual air pollution report released Wednesday by the Environmental Protection Agency. (ewg.org)
  • Today American Oversight and the Environmental Working Group petitioned the Environmental Protection Agency for release of documents detailing contacts between former EPA chief Scott Pruitt and the chemical industry ahead of the agency's decision to exclude major sources of exposure when evaluating the health risks of asbestos and three other highly toxic chemicals. (ewg.org)
  • During the early hours of January 15, the U.S. Environmental Protection Agency, at the request of state and local authorities, responded to a reported chlorine gas release at a private residence on Camano Island WA, a rural area 60 miles north of Seattle. (environmental-expert.com)
  • The U.S. Environmental Protection Agency (EPA) reached a settlement with Amalgamated Sugar Company LLC (Amalgamated Sugar) for failing to properly report the release of dangerous chlorine gas at its Paul, Idaho facility. (environmental-expert.com)
  • Darigold Inc. failed to immediately notify federal and state emergency authorities of a chlorine gas release in 2012 at a milk facility in Portland, Oregon, according to a settlement with the U.S. Environmental Protection Agency. (environmental-expert.com)
  • Unified Grocers has settled with the U.S. Environmental Protection Agency (EPA) for alleged chemical release reporting, risk management, and emergency planning violations at its warehouse facility in Seattle, Washington and will pay EPA a $110,200 penalty. (environmental-expert.com)
  • A video news release (VNR) is a video segment made to look like a news report, but is instead created by a PR firm, advertising agency, marketing firm, corporation, or government agency. (wikipedia.org)
  • In a report released on April 6, 2006, the Center for Media and Democracy listed detailed information on 77 television stations that it said had broadcast VNRs in the prior 10 months, and which VNRs had been broadcast. (wikipedia.org)
  • BOSTON - Saying that Massachusetts' state trial courts "are already operating on the brink" following cuts of $24.4 million to the judiciary budget in Fiscal Year 2010, the Boston Bar Association today released a report warning that any additional budget cuts -- such as the additional $10 million reduction proposed by House One -- would decimate critical services for the most disadvantaged Massachusetts residents and pose serious risks to public safety. (bostonbar.org)
  • The top Republican on the congressional committee investigating whether Roger Clemens used performance-enhancing drugs released a report Tuesday questioning whether the seven-time Cy Young Award winner lied in his testimony before the panel last month. (deseretnews.com)
  • Davis said in a release accompanying the report. (deseretnews.com)
  • Released this month from the Institute of Food Technologists® (IFT) is a Scientific Status Summary (SSS), a peer-reviewed report published in the Journal of Food Science. (ift.org)
  • By law, facilities are required to report hazardous releases to state and federal emergency response authorities in a timely manner. (environmental-expert.com)
  • List ordered by date released, descending. (epa.gov)
  • Although we are certain the mod will be ready very soon, we will not be setting a firm release date as residual bugs do occasionally pop up, and we want to be as extensive as possible in making the game as balanced and free from bugs as we can. (moddb.com)
  • Those maps not completed will be released at a later date on the website. (moddb.com)
  • Stay up-to-date on the biggest health and wellness news with our weekly recap. (foxnews.com)
  • For more information about this archival news release, please contact Christine Flowers , Director, Office of Communications & Public Liaison at (919) 541-3665. (nih.gov)
  • Four northwest companies (2 in Washington, 1 in Oregon, 1 in Idaho) have agreed to follow federal requirements when it comes to reporting the storage, handling, and accidental release of hazardous chemicals. (environmental-expert.com)
  • The Palm Beach County State Attorney's Office had filed a notice Wednesday saying it believes the videos are public records under Florida law and it plans to release pixilated versions. (go.com)
  • Spokesman Mike Edmondson said the release is not imminent, as the office is processing numerous public records in the case. (go.com)
  • It is with great sadness that the Executive Office and staff of the Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) learned of the passing of Louis Berlinguet this past Sunday at the age of 91. (irsst.qc.ca)
  • The Office of Electricity Delivery and Energy Reliability (OE) has released the third issue of the Energy Emergency Preparedness Quarterly (EEPQ), designed to briefly highlight a few of the energy preparedness activities that occur each quarter. (environmental-expert.com)
  • Remember to keep active on the forums and IRC channel, which is where the latest news can be picked up, as well as new developer diaries to give you more of an insight into SourceForts development. (moddb.com)
  • Latest news and information from the unique perspective of the National Health Federation. (thenhf.com)
  • Today, the IAQ Video Network and Cochrane & Associates announced the release of their latest educational video. (environmental-expert.com)
  • See the navigation bar at the right side of the news release text for links to data tables, contact personnel and their telephone numbers, and supplementary materials. (bea.gov)
  • Technical information: Household data: (202) 691-6378 USDL 08-0448 http://www.bls.gov/cps/ Establishment data: (202) 691-6555 Transmission of material in this release http://www.bls.gov/ces/ is embargoed until 8:30 A.M. (EDT), Media contact: (202) 691-5902 Friday, April 4, 2008. (bls.gov)
  • Download 40dpi JPEG image, brinker_birds.jpg , 76K (Media are welcome to download/publish this image with related news stories. (sandia.gov)
  • ATSDR has issued 1 news release about the Gorham Silver site. (cdc.gov)
  • Transmission of material in this release is embargoed until USDL-15-0610 8:30 a.m. (bls.gov)
  • The new research, which is detailed in Biomaterials , showed that slow-release peptide gels could continuously deliver immunotherapy drugs to tumor sites for long periods of time. (rice.edu)
  • At its recent regular meeting, the board of directors of the Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) appointed some new members to the research ethics committee (REC) for three-year terms. (irsst.qc.ca)
  • Tap water supplies for more than 14 million Americans are contaminated with a cancer-causing industrial solvent made notorious by the book and film "A Civil Action," according to an Environmental Working Group investigation released today. (ewg.org)
  • This release of Plasma brings many improvements to the task manager, KRunner, activities, and Wayland support as well as a much more refined look and feel. (kde.org)
  • News producers may air VNRs, in whole or in part, at their discretion or incorporate them into news reports if they contain information appropriate to a story or of interest to viewers. (wikipedia.org)
  • offers eligible public information officers paid access to a reliable news release distribution service. (eurekalert.org)
  • But the 29-year-old was released from hospital in March of this year, and has since been living in a hostel in the local area, being monitored by a public protection panel. (bbc.co.uk)
  • Tom Bowden said his release made him as much a risk to himself as to the public. (bbc.co.uk)
  • As part of the restoration planning process, the trustees released a draft plan in February 2009 for public review and comment, and held a public meeting to solicit input from stakeholders. (fws.gov)
  • Data in this release are annual averages. (bls.gov)
  • The NASA Planetary Data System announces the fourth release of data from the Mars Science Laboratory (MSL) mission, covering data acquired from Sol 270 through Sol 359 (May 9, 2013, to Aug 10, 2013). (usra.edu)
  • A VNR financed by the Department of Health and Human Services was aired on a number of local news programs around the country, as conventional journalism when in fact, it was produced to promote the new Medicare plan. (wikipedia.org)
  • You will stay abreast of important issues affecting health and health freedom with our complimentary, members-only quarterly flagship Health Freedom News™ magazine . (thenhf.com)
  • The MDP hydrogel provides a unique environment for the release of CDN that other gels just can't match," Hartgerink said. (rice.edu)
  • German Chancellor Angela Merkel says her government wants to secure the release of two foreigners arrested in Iran - believed to be German reporters. (bbc.co.uk)
  • Select a release year. (usitc.gov)
  • Following a rather unfortunate last two months, the SourceForts Team is now back on track with v2.0.0 well on its way, and we hope to give you more news later this year regarding its progress. (moddb.com)
  • Given this year for the first time, this award went to two researchers: Dr. Jérémie Voix, a professor and researcher at the École de technologie supérieure (ÉTS), and Dr. Franck Sgard, a researcher at the Institut de recherche Robert-Sauvé en santé et sécurité du travail (IRSST) and associate professor at the ÉTS and the Université de Sherbrooke. (irsst.qc.ca)
  • Todo lo relacionado al contenido de Red Hat (imágenes y videos) que podrá utilizar en su contenido. (redhat.com)
  • The New York Times reported in March 2005 that "In all, at least 20 federal agencies, including the Defense Department and the Census Bureau, have made and distributed hundreds of television news segments in the past four years, records and interviews show. (wikipedia.org)
  • The names of the deceased will be withheld for 24 hours pending release by the U.S. Department of Defense. (oregon.gov)
  • The Defense Department will establish a new task force to address drinking water contamination from the toxic fluorinated chemicals known as PFAS at military facilities and in nearby communities, according to a news release by Sen. Jeanne Shaheen (D-N.H. (ewg.org)
  • Lawyers representing tobacco-company defendants said they believed the department was required to confer with them before the proposed statements are eventually released publicly. (foxnews.com)