Neuroepithelial Bodies
APUD Cells
Neuroepithelial Cells
Neurosecretory Systems
Neoplasms, Neuroepithelial
Chemoreceptor Cells
Lung
Respiratory Mucosa
Na(+)/K(+) -ATPase as a marker for detecting pulmonary sensory receptors. (1/12)
Pulmonary vagal afferents provide some of the most important breathing control inputs to the respiratory center. However, the structure of vagal receptors is not yet well known. Lack of an available and effective method to identify pulmonary receptors is the major limiting factor. Here we describe a new approach using confocal microscopy to examine the structure of immunohistochemically stained airway receptors by using Na(+)/K(+)-ATPase as a marker. This method permits detailed observation of pulmonary receptor structures and their relationship to target tissue in the rabbit. The parent axon has multiple branches that supply the receptor structure. Each structure has multiple endings that form leaf-like terminals. This technique permits examining pulmonary receptor structures in detail, and should assist in identifying the morphology of the receptors and the mechanisms of receptor activation. (+info)An overview of vagal airway receptors. (2/12)
Breathing is critically depending on a variety of sensory feedbacks from multiple sources for its optimal performance. The sensory information from the lung and airways probably provides one of the most important feedbacks to adjust the respiratory controller to generate optimal breathing movements. Since Breuer and Hering made the seminal report regarding role of the vagus nerve in control of breathing in 1868, airway sensory receptors have been a subject for intensive and extensive studies. After more than a century investigation, our knowledge accumulates immensely, however, our understanding of the nature of these sensory receptors is still far from complete. This brief review provides an overview on this topic. (+info)Functional facets of the pulmonary neuroendocrine system. (3/12)
Pulmonary neuroendocrine cells (PNECs) have been around for 60 years in the scientific literature, although phylogenetically they are ancient. Their traditionally ascribed functions include chemoreception and regulation of lung maturation and growth. There is recent evidence that neuroendocrine (NE) differentiation in the lung is regulated by genes and pathways that are conserved in the development of the nervous system from Drosophila to humans (such as achaete-scute homolog-1), or implicated in the carcinogenesis of the nervous or NE system (such as the retinoblastoma tumor suppressor gene). In addition, complex neural networks are in place to regulate chemosensory and other functions. Even solitary PNECs appear to be innervated. For the first time ever, we have mouse models for lung NE carcinomas, including the most common and virulent small cell lung carcinoma. Moreover, PNECs may be important for inflammatory responses, and pivotal for lung stem cell niches. These discoveries signify an exciting new era for PNECs and are likely to have therapeutic and diagnostic applications. (+info)Pulmonary neuroendocrine cells, airway innervation, and smooth muscle are altered in Cftr null mice. (4/12)
The amine- and peptide-producing pulmonary neuroendocrine cells (PNEC) are widely distributed within the airway mucosa of mammalian lung as solitary cells and innervated clusters, neuroepithelial bodies (NEB), which function as airway O2 sensors. These cells express Cftr and hence could play a role in the pathophysiology of cystic fibrosis (CF) lung disease. We performed confocal microscopy and morphometric analysis on lung sections from Cftr-/- (null), Cftr+/+, and Cftr+/- (control) mice at developmental stages E20, P5, P9, and P30 to determine the distribution, frequency, and innervation of PNEC/NEB, innervation and cell mass of airway smooth muscle, and neuromuscular junctions using synaptic vesicle protein 2, smooth muscle actin, and synaptophysin markers, respectively. The mean number of PNEC/NEB in Cftr-/- mice was significantly reduced compared with control mice at E20, whereas comparable or increased numbers were observed postnatally. NEB cells in Cftr null mice showed a significant reduction in intracorpuscular nerve endings compared with control mice, which is consistent with an intrinsic abnormality of the PNEC system. The airways of Cftr-/- mice showed reduced density (approximately 20-30%) of smooth muscle innervation, decreased mean airway smooth muscle mass (approximately 35%), and reduced density (approximately 20%) of nerve endings compared with control mice. We conclude that the airways of Cftr-/- mice exhibit heretofore unappreciated structural alterations affecting cellular and neural components of the PNEC system and airway smooth muscle and its innervation resulting in blunted O2 sensing and reduced airway tonus. Cftr could play a role in the development of the PNEC system, lung innervation, and airway smooth muscle. (+info)Characterization of slowly inactivating KV{alpha} current in rabbit pulmonary neuroepithelial bodies: effects of hypoxia and nicotine. (5/12)
Pulmonary neuroepithelial bodies (NEB) form innervated cell clusters that express voltage-activated currents and function as airway O(2) sensors. We investigated A-type K(+) currents in NEB cells using neonatal rabbit lung slice preparation. The whole cell K(+) current was slowly inactivating with activation threshold of approximately -30 mV. This current was blocked approximately 27% by blood-depressing substance I (BDS-I; 3 microM), a selective blocker of Kv3.4 subunit, and reduced approximately 20% by tetraethylammonium (TEA; 100 microM). The BDS-I-sensitive component had an average peak value of 189 +/- 14 pA and showed fast inactivation kinetics that could be fitted by one-component exponential function with a time constant of (tau1) 77 +/- 10 ms. This Kv slowly inactivating current was also blocked by heteropodatoxin-2 (HpTx-2; 0.2 microM), a blocker of Kv4 subunit. The HpTx-2-sensitive current had an average peak value of 234 +/- 23 pA with a time constant (tau) 82 +/- 11 ms. Hypoxia (Po(2) = 15-20 mmHg) inhibited the slowly inactivating K(+) current by approximately 47%, during voltage steps from -30 to +30 mV, and no further inhibition occurred when TEA was combined with hypoxia. Nicotine at concentrations of 50 and 100 microM suppressed the slowly inactivating K(+) current by approximately 24 and approximately 40%, respectively. This suppression was not reversed by mecamylamine suggesting a direct effect of nicotine on these K(+) channels. In situ hybridization experiments detected expression of mRNAs for Kv3.4 and Kv4.3 subunits, while double-label immunofluorescence confirmed membrane localization of respective channel proteins in NEB cells. These studies suggest that the hypoxia-sensitive current in NEB cells is carried by slowly inactivating A-type K(+) channels, which underlie their oxygen-sensitive potassium currents, and that exposure to nicotine may directly affect their function, contributing to smoking-related lung disease. (+info)Functional live cell imaging of the pulmonary neuroepithelial body microenvironment. (6/12)
(+info)Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. (7/12)
(+info)Recruitment of GABA(A) receptors in chemoreceptor pulmonary neuroepithelial bodies by prenatal nicotine exposure in monkey lung. (8/12)
(+info)Neuroepithelial bodies (NEBs) are clusters of neuroepithelial cells that are found in the airway epithelium, primarily in the intrapulmonary airways. These cells are capable of detecting chemical irritants and mechanical distortion within the airways and play a role in the regulation of breathing. NEBs contain chemoreceptors that respond to changes in oxygen and carbon dioxide levels, as well as other chemicals, and can stimulate neural reflexes that lead to changes in breathing pattern and depth. They are also thought to play a role in the development and maintenance of the airway epithelium. NEBs have been implicated in various respiratory disorders, including chronic obstructive pulmonary disease (COPD) and asthma.
APUD cells are a type of neuroendocrine cell that originated from the neural crest and are widely distributed throughout the body. The term "APUD" is an acronym for "Amine Precursor Uptake and Decarboxylation," which describes the ability of these cells to take up and decarboxylate amino acid precursors to produce biologically active amines, such as serotonin, histamine, and catecholamines.
APUD cells are capable of synthesizing, storing, and releasing hormones or neurotransmitters in response to various stimuli. They can be found in several endocrine and neural tissues, including the thyroid gland, adrenal medulla, pituitary gland, pancreas, lungs, and gastrointestinal tract.
In the gastrointestinal tract, APUD cells are often referred to as enterochromaffin cells or Kulchitsky cells. They play a crucial role in regulating gut motility, secretion, and blood flow through the release of hormones such as serotonin, gastrin, and somatostatin.
It's worth noting that the APUD cell concept has been largely replaced by the more comprehensive neuroendocrine system concept, which encompasses a broader range of cells with neurosecretory functions.
Neuroepithelial cells are stem cells that line the developing central nervous system (CNS) in embryos. These cells have the ability to differentiate into various cell types, including neurons and glial cells, which make up the brain and spinal cord. Neuroepithelial cells form a pseudostratified epithelium, meaning that the nuclei of the cells are at varying heights within the cell layer, giving it a striped appearance. These cells play a crucial role in the development and growth of the CNS.
Neurosecretory systems are specialized components of the nervous system that produce and release chemical messengers called neurohormones. These neurohormones are released into the bloodstream and can have endocrine effects on various target organs in the body. The cells that make up neurosecretory systems, known as neurosecretory cells, are found in specific regions of the brain, such as the hypothalamus, and in peripheral nerves.
Neurosecretory systems play a critical role in regulating many physiological processes, including fluid and electrolyte balance, stress responses, growth and development, reproductive functions, and behavior. The neurohormones released by these systems can act synergistically or antagonistically to maintain homeostasis and coordinate the body's response to internal and external stimuli.
Neurosecretory cells are characterized by their ability to synthesize and store neurohormones in secretory granules, which are released upon stimulation. The release of neurohormones can be triggered by a variety of signals, including neural impulses, hormonal changes, and other physiological cues. Once released into the bloodstream, neurohormones can travel to distant target organs, where they bind to specific receptors and elicit a range of responses.
Overall, neurosecretory systems are an essential component of the neuroendocrine system, which plays a critical role in regulating many aspects of human physiology and behavior.
Neuroepithelial neoplasms are a type of tumor that arises from the neuroepithelium, which is the tissue in the developing embryo that gives rise to the nervous system. These tumors can occur anywhere along the nervous system, including the brain and spinal cord (central nervous system) or the peripheral nerves.
Neuroepithelial neoplasms can be benign or malignant, and they can vary widely in their behavior and prognosis. Some common types of neuroepithelial neoplasms include:
1. Astrocytomas: These are tumors that arise from astrocytes, a type of star-shaped glial cell in the brain. Astrocytomas can be low-grade (slow-growing) or high-grade (fast-growing), and they can occur in different parts of the brain.
2. Oligodendrogliomas: These are tumors that arise from oligodendrocytes, a type of glial cell that provides support and insulation to nerve cells in the brain. Oligodendrogliomas are typically low-grade and slow-growing.
3. Ependymomas: These are tumors that arise from the ependyma, which is the tissue that lines the ventricles (fluid-filled spaces) in the brain and the spinal cord canal. Ependymomas can be benign or malignant, and they can occur in the brain or the spinal cord.
4. Medulloblastomas: These are fast-growing tumors that arise from primitive neuroectodermal cells in the cerebellum (the part of the brain that controls balance and coordination). Medulloblastomas are highly malignant and can spread to other parts of the brain and spinal cord.
5. Glioblastomas: These are the most common and aggressive type of primary brain tumor. They arise from astrocytes and can grow rapidly, invading surrounding brain tissue.
Neuroepithelial neoplasms are typically treated with surgery, radiation therapy, and chemotherapy, depending on the type and location of the tumor. The prognosis varies widely depending on the specific type and stage of the tumor.
Chemoreceptor cells are specialized sensory neurons that detect and respond to chemical changes in the internal or external environment. They play a crucial role in maintaining homeostasis within the body by converting chemical signals into electrical impulses, which are then transmitted to the central nervous system for further processing and response.
There are two main types of chemoreceptor cells:
1. Oxygen Chemoreceptors: These cells are located in the carotid bodies near the bifurcation of the common carotid artery and in the aortic bodies close to the aortic arch. They monitor the levels of oxygen, carbon dioxide, and pH in the blood and respond to decreases in oxygen concentration or increases in carbon dioxide and hydrogen ions (indicating acidity) by increasing their firing rate. This signals the brain to increase respiratory rate and depth, thereby restoring normal oxygen levels.
2. Taste Cells: These chemoreceptor cells are found within the taste buds of the tongue and other areas of the oral cavity. They detect specific tastes (salty, sour, sweet, bitter, and umami) by interacting with molecules from food. When a tastant binds to receptors on the surface of a taste cell, it triggers a series of intracellular signaling events that ultimately lead to the generation of an action potential. This information is then relayed to the brain, where it is interpreted as taste sensation.
In summary, chemoreceptor cells are essential for maintaining physiological balance by detecting and responding to chemical stimuli in the body. They play a critical role in regulating vital functions such as respiration and digestion.
A lung is a pair of spongy, elastic organs in the chest that work together to enable breathing. They are responsible for taking in oxygen and expelling carbon dioxide through the process of respiration. The left lung has two lobes, while the right lung has three lobes. The lungs are protected by the ribcage and are covered by a double-layered membrane called the pleura. The trachea divides into two bronchi, which further divide into smaller bronchioles, leading to millions of tiny air sacs called alveoli, where the exchange of gases occurs.
Respiratory mucosa refers to the mucous membrane that lines the respiratory tract, including the nose, throat, bronchi, and lungs. It is a specialized type of tissue that is composed of epithelial cells, goblet cells, and glands that produce mucus, which helps to trap inhaled particles such as dust, allergens, and pathogens.
The respiratory mucosa also contains cilia, tiny hair-like structures that move rhythmically to help propel the mucus and trapped particles out of the airways and into the upper part of the throat, where they can be swallowed or coughed up. This defense mechanism is known as the mucociliary clearance system.
In addition to its role in protecting the respiratory tract from harmful substances, the respiratory mucosa also plays a crucial role in immune function by containing various types of immune cells that help to detect and respond to pathogens and other threats.
The optic lobe in non-mammals refers to a specific region of the brain that is responsible for processing visual information. It is a part of the protocerebrum in the insect brain and is analogous to the mammalian visual cortex. The optic lobes receive input directly from the eyes via the optic nerves and are involved in the interpretation and integration of visual stimuli, enabling non-mammals to perceive and respond to their environment. In some invertebrates, like insects, the optic lobe is further divided into subregions, including the lamina, medulla, and lobula, each with distinct functions in visual processing.
Serotonin
Hypoxic pulmonary vasoconstriction
Lung
Dysembryoplastic neuroepithelial tumour
Ctenophorus caudicinctus
Neuro-oncology
Hypoxia in fish
Lateral ventricles
Indole-3-acetic acid
Iris cyst
List of MeSH codes (A11)
Neuroectoderm
Epithelium
Neuroendocrine cell
List of MeSH codes (A08)
Nervous tissue
Perivascular space
NTERA-2
Ontogeny
Follower neuron
Astroblastoma
Diktyoma
Brain tumor
Photoreceptor cell
Development of the nervous system in humans
List of MeSH codes (C04)
Radial glial cell
Medulloepithelioma
Zona limitans intrathalamica
Netrin
Neuroepithelial Body Microenvironment Is a Niche for a Distinct Subset of Clara-Like Precursors in the Developing Airways
Hyperplasia of Pulmonary Neuroepithelial Bodies (NEB) in Lungs of Prolyl Hydroxylase −1(PHD-1) Deficient Mice - Nuffield...
Serotonin - Wikipedia
Hyperplasia of pulmonary neuroepithelial bodies (NEB) in lungs of prolyl hydroxylase -1(PHD-1) deficient mice - NDM Research...
TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications | European Respiratory Society
Plasticity in the lung: making and breaking cell identity | Development | The Company of Biologists
Actin
Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs...
ASH1L | Cancer Genetics Web
Neural System Development - Embryology
Ryann Fame's Profile | Stanford Profiles
Engineered Cerebral Organoids Recapitulate Adult Tau Expression and Disease-relevant Changes in Tau Splicing | Research Square
Frontiers | Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived...
Bio2Vec
Apoptosis
Research on the effectiveness and safety of bronchial thermoplasty in patients with chronic obstructive pulmonary disease |...
Namespace
Phenotypic Analysis of Stem Cell Microenvironments Within the Conducting Airway Epithelium - D-Scholarship@Pitt
Tiansong Lin - NeL.edu
May | 2017 | Erk signaling
Dr. Arjun Guha - Publications | InStem
...
Dallas Hyde | UC Davis Profiles
Wyniki wyszukiwania
Búsqueda | BVS Bolivia
Schinzel-Giedion syndrome: MedlinePlus Genetics
Hamartoma: Practice Essentials, Pathophysiology, Etiology
MESH TREE NUMBER CHANGES - 2015 MeSH
MESH TREE NUMBER CHANGES - 2015 MeSH
Dysembryoplastic3
- Are you trying to schedule an appointment for the Dysembryoplastic Neuroepithelial Tumor? (nicklauschildrens.org)
- What are the symptoms of dysembryoplastic neuroepithelial tumor? (nicklauschildrens.org)
- What are dysembryoplastic neuroepithelial tumor care options? (nicklauschildrens.org)
Tumors3
- Children with Schinzel-Giedion syndrome who survive past infancy have a higher than normal risk of developing certain types of brain tumors called neuroepithelial tumors. (medlineplus.gov)
- Primary neuroendocrine tumors of the lung NTLs originate either from Kulchitzky cells, neuroepithelial bodies or from pluripotent stem cells which are present in the bronchial mucosa, with similar pathological features, and being capable of producing and secreting peptide hormones and neuroamines 2. (adventube.ro)
- Gliomas, tumors derived from neuroepithelial cells (astrocytes, oligodendrocytes, and ependymal cells), account for the majority of these primary CNS tumors. (cdc.gov)
NEBs1
- Furthermore, we identified a subpopulation of secretory precursors juxtaposed to presumptive neuroepithelial bodies (NEBs), distinguished by their strong Scgb3a2 and uroplakin 3a (Upk3a) signals and reduced Ccsp (Scgb1a1) expression. (harvard.edu)
Cells16
- Approximately 90% of the serotonin the human body produces is in the gastrointestinal tract's enterochromaffin cells, where it regulates intestinal movements. (wikipedia.org)
- It plays a significant role in eliminating unhealthy or exhausted cells from the body and its involvement in many biological processes has been well characterized. (utoronto.ca)
- Previous results indicated that intrapulmonary conducting airways contain rare populations of stem cells that localized to neuroepithelial body (NEB) microenvironments, and that these cells are activated following injury involving depletion of airway Clara cells. (pitt.edu)
- Sonic hedgehog overexpression regulates the neuroepithelial cells proliferation in the spinal cord of dorsal regions during chicken embryo development. (nel.edu)
- Yang C, Li X, Liu Y, Li H, Guo Z, Lin J. Sonic hedgehog overexpression regulates the neuroepithelial cells proliferation in the spinal cord of dorsal regions during chicken embryo development. (nel.edu)
- The simultaneous presence of neuroepithelial cells and neuroepithelial bodies in the respiratory gas bladder of the longnose gar, Lepisosteus osseus , and the spotted gar, L. oculatus . (krakow.pl)
- A hamartoma (from Greek hamartia, meaning "fault, defect," and -oma, denoting a tumor or neoplasm) is a benign (noncancerous) tumorlike malformation made up of an abnormal mixture of cells and tissues found in areas of the body where growth occurs. (medscape.com)
- Though there offers been progress in understanding the function of NE cells, the physiological part of NE cells in most additional body organs is definitely not well recognized. (brain-tumor-cancer-information.com)
- We investigated whether this sensitivity is maintained in trout chronically exposed (1+ months) to high environmental ammonia [HEA, 250 μmol l -1 (NH 4 ) 2 SO 4 ] in the water, and whether gill neuroepithelial cells (NECs) are involved in ammonia sensing. (silverchair.com)
- As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
- In the ventricular and subventricular regions of trout telencephalon, CBS+ cells, as well as neuroepithelial and glial types, were detected. (intechopen.com)
- As a result of injury, the number of CBS+ neuroepithelial cells in the pallial and subpallial periventricular regions of the telencephalon increases. (intechopen.com)
- In the tectum, a traumatic damage leads to an increase in the CBS expression in radial glia with a simultaneous decrease in the number of CBS immunopositive neuroepithelial cells detected in intact animals. (intechopen.com)
- These markers of senescence specifically appeared in exposed neuroepithelial cells, a type of stem cell that later produces brain cells. (livescience.com)
- The researchers exposed the organoids to valproic acid and found that the drug pushed the organoids' neuroepithelial cells into senescence, just as it had in the mouse embryos. (livescience.com)
- Altered G Protein Coupling in Olfactory Neuroepithelial Cells From Patients With Schizophrenia. (jefferson.edu)
Ciliary body1
- The lens is suspended by ligaments (called zonule fibers) attached to the anterior portion of the ciliary body. (utah.edu)
Respiratory1
- The nose and the oral cavities are the main sites for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry into the body. (wjgnet.com)
Symptoms1
- When your body releases too much histamine or is unable to break it down, it can cause symptoms that we typically associate with allergic reactions, such as: nasal congestion hives headaches itchy skin rapid heartbeat flushing difficulty breathing. (tinkerstorm.de)
PATHWAY1
- In this review, we summarize recent studies that have explored the relationship between the Hippo signaling pathway and growth of optic neuroepithelial compartments. (molcells.org)
20221
- Jun 10, 2022 · How do high levels of histamine affect the body? (tinkerstorm.de)
Histamine2
- Overall it is clear that there is an interconnection in the body between histamine , oestrogen, progesterone and cortisol in regards to systemic functionality. (tinkerstorm.de)
- Histamine is a biogenic amine, widely distributed in the body. (geneceutica.ro)
Iris1
- The sagittal section of the eye also reveals the lens which is a transparent body located behind the iris. (utah.edu)
Systems1
- Schinzel-Giedion syndrome is a severe condition that is apparent at birth and affects many body systems. (medlineplus.gov)
Affects1
- When taken as a treatment for epilepsy or bipolar disorder, valproic acid affects the body in several ways, according to the online medical database StatPearls . (livescience.com)
Growth2
- Uncomplicated hamartomas have no tendency to grow, except as determined by the normal growth controls of the body. (medscape.com)
- The fish brain has a unique feature of vertebrates-it grows with the growth of body over a lifetime. (intechopen.com)
Regulation1
- It is involved in various processes of the body, including digestive processes, vascular regulation, allergic reactions and inflammatory processes. (geneceutica.ro)
Found1
- The SETBP1 protein is found throughout the body, but protein levels are highest during brain development before birth. (medlineplus.gov)
Parts1
- But it's also involved in digestion, and boosting exercise performance, and increasing attention, as well as getting nutrients and oxygen delivered to different parts of the body. (tinkerstorm.de)
Impact1
- So you can always keep the source of the EMF far enough away from you to minimize the impact to your beautiful body. (techwellness.com)
Levels1
- If cortisol levels in the body are low, inflammation goes unchecked. (tinkerstorm.de)
Organoids1
- Optogenetic manipulation of apical constriction caused multiple types of tissue deformation, including neuroepithelial thickening and apical lumen shrinkage of neural organoids (Figure 4). (embl.org)
Pulmonary1
- Pulmonary neuroepithelial bodies (NEB) are presumed airway chemoreceptors involved in respiratory control, especially in the neonate. (mcmaster.ca)
Apical1
- During cortical development, RGs are present in different strategic positions: apical RGs (aRGs) have their cell bodies located in the ventricular zone with an apical process contacting the ventricle, while they also have a basal process extending radially to reach the pial surface of the cortex. (frontiersin.org)
Epithelium1
- In the adult ciliary body, VEGF-A was expressed by the pigmented epithelium, whereas VEGFR2 was localized primarily to the capillary endothelium and nonpigmented epithelium. (arvojournals.org)
Lung1
- It is rare for medulloblastomas to spread to the bone, bone marrow , lung , or other parts of the body. (oncolink.org)
Tissue1
- The part of the nasal mucosa composed of neuroepithelial tissue and mucus-producing Bowman's glands. (medindex.am)
Adult2
- Banaceur S, Banasr S, Sakly M et al (2013) Whole body exposure to 2.4 GHz WIFI signals: effects on cognitive impairment in adult triple transgenic mouse models of Alzheimer's disease (3xTg-AD). (springer.com)
- In normal control adult mouse eyes, ETS-1 was mostly present in the nuclei of all neuroretinal layers whereas ETS-2 was mostly localized in the cytosol of the cell bodies of these layers with a smaller amount present in the nuclei. (molvis.org)
Systemic1
- These data suggest that kidney ACE activity decrease are due to renal damage and an universal signal increases the ACE contents in the body probably to increase systemic blood pressure and subsequently increase glomerular filtration rate (GFR). (ac.ir)
Distinct1
- 2. Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumor s. (nih.gov)
Axons2
- This makes it ideal for localising not only degenerating nerve cell bodies but also distal dendrites, axons and terminals. (newmarketscientific.com)
- In line with this, Hinds and Hinds [ 14 ], in their serial electron microscopic studies of the developing mouse retina, suggested that the axons of RGCs arise from the basal process of neuroepithelial-like precursors. (biomedcentral.com)
Oxygen1
- The significance of this is that fat and ketone bodies as a source of energy require oxygen while glucose doesn't. (second-opinions.co.uk)
Brain5
- Castaño-Vinyals G, Sadetzki S, Vermeulen R et al (2022) Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: results from the international MOBI-Kids study. (springer.com)
- A brain tumor that starts in another part of the body and spreads to the brain is called a metastatic tumor. (shyamhemoncclinic.com)
- The brain controls many important body functions. (shyamhemoncclinic.com)
- The spinal cord connects the brain to nerves in most parts of the body. (shyamhemoncclinic.com)
- Spinal cord nerves carry messages between the brain and the rest of the body, such as a signal from the brain to cause muscles to move or from the skin to the brain about the sense of touch. (shyamhemoncclinic.com)
Organ1
- Nevertheless, soluble elements or cytokines that control the locks cell differentiation in the body organ of Corti stay to become elucidated. (immune-source.com)
Nerves1
- a protein which aids the formation Lewy bodies that develop inside nerves. (lagas.org)
Disease1
- Due to these pathophysiologicalcharacteristics, PD clinical motor symptoms range from muscular rigidity to akinesia,resting tremor, postural instability and lately, in several nonmotor symptoms.Intracellular inclusions of aggregated α-synuclein (α-Syn) in the form of Lewy Bodies(LBs) are the main hallmark of this disease. (uc.pt)
Biology2
- As part of his studies on Cell biology, Kenneth H. Pollock often connects relevant areas like Neuroepithelial cell. (research.com)
- His work on Neuroepithelial cell is being expanded to include thematically relevant topics such as Cell biology. (research.com)
Process1
- All of the process let cell to controlled internal space also body fluids. (geneandcells.com)
Increases1
- This vicious cycle increases body wasting,[3] which is one reason some 40% of patients die from malnutrition (cachexia). (second-opinions.co.uk)
Function1
- Prenatal WiFi exposure increased the body weight, improved the spatial memory and learning function, and induced behavioral hyperactivity of male rats. (springer.com)
WEIGHT2
- Ethylene thiourea is teratogenic to rats and the overall NOAEL for the teratogenic effect on this species is estimated to be 5 mg per kilogram body weight per day. (europa.eu)
- On PND7-42, we evaluated the development and behavior of the offspring, including body weight, pain threshold, and swimming ability, spatial learning, and memory among others. (springer.com)
Bone1
- One of bone cell in our body also called osteocyte. (geneandcells.com)
Parts of the body1
- They may also spread to other parts of the body, but this is rare. (oncolink.org)
Access1
- Mosaic analysis in four dimensions, using mutants in which neuroepithelial polarity is disrupted, indicates that extrinsic factors such as access to the basal lamina are critical for normal axon emergence from RGCs in vivo . (biomedcentral.com)
Normal1
- Uncomplicated hamartomas have no tendency to grow, except as determined by the normal growth controls of the body. (medscape.com)
Cell body1
- The techniques that follow to attain the motility routine consist of formation of adhesion buildings that stabilize the protrusion [7] advancement of contractile drive that translocates the cell body forwards discharge of adhesion buildings on the cell back and lastly retraction from the cell to the path of motility [8]. (biodiversityhotspot.org)
Male1
- Hereby we would like to present a case report of a 27-year-old male patient with drug- -resistant structural epilepsy based on the diagnosis of the polymorphous low-grade neuroepithelial tumor of the young (PLNTY), first reported by Huse et al in 2017 [1]. (muni.cz)
Effects1
- So that day after day, week after week, year after year, your body is being exposed to radiation that has been proven to have biological effects. (techwellness.com)