Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
Viral infections of the brain, spinal cord, meninges, or perimeningeal spaces.
An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions.
Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.
The main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
A strain of ENCEPHALOMYOCARDITIS VIRUS, a species of CARDIOVIRUS, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis.
A watery fluid that is continuously produced in the CHOROID PLEXUS and circulates around the surface of the BRAIN; SPINAL CORD; and in the CEREBRAL VENTRICLES.
The three membranes that cover the BRAIN and the SPINAL CORD. They are the dura mater, the arachnoid, and the pia mater.
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
Enterovirus infections are a group of viral illnesses caused by enteroviruses that primarily affect the respiratory, gastrointestinal, and central nervous systems.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal nerves, autonomic ganglia, and plexuses. (Stedman, 26th ed)
The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Diseases of the parasympathetic or sympathetic divisions of the AUTONOMIC NERVOUS SYSTEM; which has components located in the CENTRAL NERVOUS SYSTEM and PERIPHERAL NERVOUS SYSTEM. Autonomic dysfunction may be associated with HYPOTHALAMIC DISEASES; BRAIN STEM disorders; SPINAL CORD DISEASES; and PERIPHERAL NERVOUS SYSTEM DISEASES. Manifestations include impairments of vegetative functions including the maintenance of BLOOD PRESSURE; HEART RATE; pupil function; SWEATING; REPRODUCTIVE AND URINARY PHYSIOLOGY; and DIGESTION.
A subclass of developmentally regulated lamins having a neutral isoelectric point. They are found to disassociate from nuclear membranes during mitosis.
Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.
Diseases in any part of the GASTROINTESTINAL TRACT or the accessory organs (LIVER; BILIARY TRACT; PANCREAS).
The nervous system outside of the brain and spinal cord. The peripheral nervous system has autonomic and somatic divisions. The autonomic nervous system includes the enteric, parasympathetic, and sympathetic subdivisions. The somatic nervous system includes the cranial and spinal nerves and their ganglia and the peripheral sensory receptors.
Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. (From Kandel, Schwartz, and Jessel, Principles of Neural Science, 3d ed, p766)
Postmortem examination of the body.
Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.
An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.
Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Characteristic properties and processes of the NERVOUS SYSTEM as a whole or with reference to the peripheral or the CENTRAL NERVOUS SYSTEM.
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Elements of limited time intervals, contributing to particular results or situations.
Benign and malignant neoplastic processes arising from or involving components of the central, peripheral, and autonomic nervous systems, cranial nerves, and meninges. Included in this category are primary and metastatic nervous system neoplasms.
An infant during the first month after birth.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.

Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor. (1/3079)

Glial cell line-derived neurotrophic factor (GDNF) and a related protein, neurturin (NTN), require a GPI-linked coreceptor, either GFR alpha1 or GFR alpha2, for signaling via the transmembrane Ret tyrosine kinase. We show that mice lacking functional GFR alpha2 coreceptor (Gfra2-/-) are viable and fertile but have dry eyes and grow poorly after weaning, presumably due to malnutrition. While the sympathetic innervation appeared normal, the parasympathetic cholinergic innervation was almost absent in the lacrimal and salivary glands and severely reduced in the small bowel. Neurite outgrowth and trophic effects of NTN at low concentrations were lacking in Gfra2-/- trigeminal neurons in vitro, whereas responses to GDNF were similar between the genotypes. Thus, GFR alpha2 is a physiological NTN receptor, essential for the development of specific postganglionic parasympathetic neurons.  (+info)

Anti-amphiphysin I antibodies in patients with paraneoplastic neurological disorders associated with small cell lung carcinoma. (2/3079)

Patients with stiff man syndrome and breast cancer develop anti-amphiphysin I antibodies that primarily recognise the C terminus of the protein. Anti-amphiphysin I antibodies have also been identified in a few patients with paraneoplastic neurological disorders (PND) and small cell lung cancer (SCLC). The frequency of anti-amphiphysin I antibodies in patients with SCLC and PND was analysed and the epitope specificity of these antibodies was characterised. Anti-amphiphysin I antibodies were evaluated by immunohistochemistry on human and rat cerebellum and immunoblots of rat brain homogenates. Serum samples included 134 patients with PND and anti-Hu antibodies (83% had SCLC), 44 with SCLC and PND without anti-Hu-antibodies, 63 with PND and either Yo, Ri, or Tr antibodies, 146 with SCLC without PND, and 104 with non-PND. Positive serum samples were confirmed with immunoblots of recombinant human amphiphysin I and immunoreacted with five overlapping peptide fragments covering the full length of the molecule. Serum samples positive for anti-amphiphysin I antibodies included those from seven (2.9%) patients with PND and two (1.4%) with SCLC without PND. Six of the seven anti-amphiphysin I antibody positive patients with PND had SCLC (three with Hu-antibodies), and one had anti-Hu-antibodies but no detectable tumour. The PND included encephalomyelitis/sensory neuropathy (five patients), cerebellar degeneration (one), and opsoclonus (one). All anti-amphiphysin I antibodies reacted with the C terminus of amphiphysin I, but seven also recognised other fragments of the molecule. In conclusion, anti-amphiphysin I antibodies are present at low frequency in patients with SCLC irrespective of the presence of an associated PND. All anti-amphiphysin I antibody positive serum samples have in common reactivity with the C terminus of the protein.  (+info)

Phase II trial of paclitaxel and cisplatin in metastatic and recurrent carcinoma of the uterine cervix. (3/3079)

PURPOSE: Both paclitaxel and cisplatin have moderate activity in patients with metastatic or recurrent cancer of the cervix, and the combination of these two agents has shown activity and possible synergism in a variety of solid tumors. We administered this combination to patients with metastatic or recurrent cervical cancer to evaluate its activity. PATIENTS AND METHODS: Thirty-four consecutive patients were treated on an outpatient basis with paclitaxel 175 mg/m2 administered intravenously over a 3-hour period followed by cisplatin 75 mg/m2 administered intravenously with granulocyte colony-stimulating factor support. The chemotherapy was administered every 3 weeks for a maximum of six courses. RESULTS: Sixteen patients (47%; 95% confidence interval, 30% to 65%) achieved an objective response, including five complete responses and 11 partial responses. Responses occurred in 28% of patients with disease within the radiation field only and in 57% of patients with disease involving other sites. The median duration of response was 5.5 months, and the median times to progression and survival for all patients were 5 and 9 months, respectively. Grade 3 or 4 toxicities included anemia in 18% of patients and granulocytopenia in 15% of patients. Fifty-three percent of patients developed some degree of neurotoxicity; 21% of cases were grade 2 or worse. CONCLUSION: The combination of paclitaxel with cisplatin seems relatively well tolerated and moderately active in patients with metastatic or recurrent cervical cancer. The significant incidence of neurotoxicity is of concern, and alternative methods of administration of the two agents could be evaluated. Then, further study of this combination, alone or with the addition of other active agents, is warranted.  (+info)

Nitric oxide, mitochondria and neurological disease. (4/3079)

Damage to the mitochondrial electron transport chain has been suggested to be an important factor in the pathogenesis of a range of neurological disorders, such as Parkinson's disease, Alzheimer's disease, multiple sclerosis, stroke and amyotrophic lateral sclerosis. There is also a growing body of evidence to implicate excessive or inappropriate generation of nitric oxide (NO) in these disorders. It is now well documented that NO and its toxic metabolite, peroxynitrite (ONOO-), can inhibit components of the mitochondrial respiratory chain leading, if damage is severe enough, to a cellular energy deficiency state. Within the brain, the susceptibility of different brain cell types to NO and ONOO- exposure may be dependent on factors such as the intracellular reduced glutathione (GSH) concentration and an ability to increase glycolytic flux in the face of mitochondrial damage. Thus neurones, in contrast to astrocytes, appear particularly vulnerable to the action of these molecules. Following cytokine exposure, astrocytes can increase NO generation, due to de novo synthesis of the inducible form of nitric oxide synthase (NOS). Whilst the NO/ONOO- so formed may not affect astrocyte survival, these molecules may diffuse out to cause mitochondrial damage, and possibly cell death, to other cells, such as neurones, in close proximity. Evidence is now available to support this scenario for neurological disorders, such as multiple sclerosis. In other conditions, such as ischaemia, increased availability of glutamate may lead to an activation of a calcium-dependent nitric oxide synthase associated with neurones. Such increased/inappropriate NO formation may contribute to energy depletion and neuronal cell death. The evidence available for NO/ONOO--mediated mitochondrial damage in various neurological disorders is considered and potential therapeutic strategies are proposed.  (+info)

The effects of specific antibody fragments on the 'irreversible' neurotoxicity induced by Brown snake (Pseudonaja) venom. (5/3079)

Brown snake (Pseudonaja) venom has been reported to produce 'irreversible' post synaptic neurotoxicity (Harris & Maltin, 1981; Barnett et al., 1980). A murine phrenic nerve/diaphragm preparation was used to study the neurotoxic effects of this venom and pre- and post-synaptic components were distinguished by varying the temperature and frequency of nerve stimulation. There were no myotoxic effects and the neurotoxicity proved irreversible by washing alone. The effects of a new Fab based ovine antivenom have been investigated and proved able to produce a complete, rapid (< 1 h) reversal of the neurotoxicity induced by Brown snake venom. A reversal was also possible when the antivenom addition was delayed for a further 60 min. We believe that this is the first time such a reversal has been shown.  (+info)

Incidence of cranial ultrasound abnormalities in apparently well neonates on a postnatal ward: correlation with antenatal and perinatal factors and neurological status. (6/3079)

AIM: To evaluate cranial ultrasonography and neurological examination in a cohort of infants regarded as normal; and to determine the prevalence of ultrasound abnormalities and any potential association with antenatal or perinatal factors or deviant neurological signs. METHODS: Cranial ultrasound findings and neurological status were evaluated in 177 newborns (gestational age 36.3 to 42 weeks), admitted to a postnatal ward directly after birth and regarded as normal by obstetric and paediatric staff. The age of the infants at the time of examination ranged between 6 and 48 hours. Ultrasound abnormalities were present in 35 of the 177 infants studied (20%). Ischaemic lesions, such as periventricular and thalamic densities were the most common finding (8%), followed by haemorrhagic lesions (6%). The possible sequelae of antenatal haemorrhages, such as focal ventricular dilatation or choroid cysts, were present in 6%. Abnormal ultrasound findings were not significantly associated with signs of perinatal distress, such as cardiotocographic abnormalities or passage of meconium. Abnormal ultrasound findings tended to be associated with antenatal problems, although this did not reach significance. Ultrasound abnormalities were strongly associated with deviant patterns on the neurological examination. CONCLUSIONS: These results suggest that ultrasound abnormalities are more common than has been reported up to now. Lesions that could be ischaemic, such as flare densities, are seen even in the absence of any antenatal or perinatal risk factor.  (+info)

Neurology and the skin. (7/3079)

As knowledge of pathophysiology grows, so does the refinement of diagnoses. Sometimes increased knowledge permits consolidation and unification. Unfortunately, at our present level of understanding, it usually demands proliferation of diagnostic categories. As tedious as this diagnostic splintering may seem, such is the price currently exacted of both the investigator and the clinician who seek to optimise management. Increased diagnostic refinement often requires inquiry into matters outside the bounds of one's specialty. Most often we turn to the radiologist or to the laboratory to narrow the differential diagnosis generated from the history and neurological examination. As we have shown, a useful intermediate step is extension of the physical examination to organs such as the skin, which are not the traditional preserve of the neurologist. That any text could confer the sophistication required for expert dermatological diagnosis is an unrealistic expectation. However, we hope that this review will encourage careful examination of the skin, hair, and nails by the neurological practitioner, with consideration of referral to a dermatologist when greater expertise is required.  (+info)

Assessing the machinery of mind: synapses in neuropsychiatric disorders. (8/3079)

Neural connectivity in postmortem human brain can now be studied with the use of antibodies that react with synapse-enriched proteins. Using a range of antibody-based techniques, the authors observed abnormalities in connectivity in Alzheimer's disease, temporal lobe epilepsy, and schizophrenia. They also found disease-related differences in the individual protein markers affected and in the anatomical distribution of differences from controls. Molecular and cellular abnormalities in neural connectivity may underlie functional abnormalities observed in vivo using positron emission tomography or functional magnetic resonance imaging.  (+info)

Central nervous system (CNS) diseases refer to disorders that affect the brain and spinal cord. These diseases can be caused by a variety of factors, including genetic mutations, infections, injuries, and degenerative processes. Some common examples of CNS diseases include: 1. Neurodegenerative diseases: These are disorders that cause the progressive loss of brain cells and function, leading to cognitive decline and physical disability. Examples include Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. Infections: Infections caused by viruses, bacteria, fungi, or parasites can affect the brain and spinal cord, leading to a range of symptoms such as fever, headache, seizures, and paralysis. 3. Trauma: Traumatic injuries to the brain and spinal cord, such as those caused by car accidents, falls, or sports injuries, can result in a range of neurological symptoms. 4. Genetic disorders: Some genetic disorders can affect the development and function of the brain and spinal cord, leading to a range of symptoms such as intellectual disability, movement disorders, and seizures. 5. Autoimmune disorders: Autoimmune disorders, such as multiple sclerosis, can cause inflammation and damage to the myelin sheath that surrounds nerve fibers in the brain and spinal cord, leading to a range of neurological symptoms. Overall, CNS diseases can have a significant impact on a person's quality of life and can be challenging to diagnose and treat.

Nervous system diseases refer to a broad range of medical conditions that affect the nervous system, which is responsible for transmitting signals between different parts of the body. These diseases can affect any part of the nervous system, including the brain, spinal cord, nerves, and muscles. Some examples of nervous system diseases include: 1. Neurodegenerative diseases: These are conditions that cause the progressive loss of nerve cells and their functions, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. Neuromuscular diseases: These are conditions that affect the muscles and nerves that control movement, such as muscular dystrophy, amyotrophic lateral sclerosis (ALS), and multiple sclerosis. 3. Neurological disorders: These are conditions that affect the brain and nervous system, such as epilepsy, stroke, and traumatic brain injury. 4. Neuropsychiatric disorders: These are conditions that affect the brain and behavior, such as schizophrenia, bipolar disorder, and depression. 5. Infections of the nervous system: These are conditions caused by infections, such as meningitis, encephalitis, and neurocysticercosis. Treatment for nervous system diseases depends on the specific condition and can include medications, surgery, physical therapy, and lifestyle changes. Early diagnosis and treatment are important for improving outcomes and managing symptoms.

Central Nervous System Viral Diseases (CNSVDs) are infections caused by viruses that affect the brain and spinal cord. These viruses can enter the central nervous system (CNS) through various routes, such as the bloodstream, respiratory system, or mucous membranes. CNSVDs can cause a range of symptoms, including fever, headache, nausea, vomiting, confusion, seizures, and paralysis. Some viruses can also cause more severe neurological complications, such as meningitis, encephalitis, or Guillain-Barré syndrome. Examples of viruses that can cause CNSVDs include herpes simplex virus, varicella-zoster virus, West Nile virus, Japanese encephalitis virus, dengue virus, and Zika virus. Treatment for CNSVDs typically involves antiviral medications, supportive care, and management of symptoms. In some cases, hospitalization may be necessary for severe cases or complications.

Meningoencephalitis is a medical condition that refers to the inflammation of both the meninges, which are the protective membranes that surround the brain and spinal cord, and the brain itself. This inflammation can be caused by a variety of factors, including viral or bacterial infections, autoimmune disorders, or certain medications. Symptoms of meningoencephalitis can include fever, headache, nausea and vomiting, sensitivity to light, confusion, seizures, and changes in mental status. In severe cases, meningoencephalitis can lead to coma or even death. Diagnosis of meningoencephalitis typically involves a combination of physical examination, medical history, and laboratory tests, such as blood tests, cerebrospinal fluid analysis, and imaging studies like MRI or CT scans. Treatment for meningoencephalitis depends on the underlying cause and can include antiviral or antibiotic medications, corticosteroids to reduce inflammation, and supportive care to manage symptoms and prevent complications. In some cases, hospitalization and intensive care may be necessary.

Central Nervous System (CNS) infections refer to infections that affect the brain and spinal cord. These infections can be caused by bacteria, viruses, fungi, or parasites, and can result in a range of symptoms, including fever, headache, nausea, vomiting, seizures, and changes in mental status or behavior. CNS infections can be classified into two main categories: primary and secondary. Primary CNS infections occur when the pathogen directly enters the brain or spinal cord, while secondary CNS infections occur when the pathogen enters the bloodstream and spreads to the brain or spinal cord. Some common examples of primary CNS infections include meningitis (inflammation of the protective membranes surrounding the brain and spinal cord), encephalitis (inflammation of the brain), and brain abscess (a localized collection of pus in the brain). Secondary CNS infections can be caused by a variety of pathogens, including bacteria (such as Streptococcus pneumoniae or Staphylococcus aureus), viruses (such as herpes simplex virus or varicella-zoster virus), and fungi (such as Cryptococcus neoformans). Treatment for CNS infections typically involves the use of antibiotics, antiviral drugs, or antifungal medications, depending on the specific pathogen causing the infection. In some cases, surgery may also be necessary to remove infected tissue or drain abscesses. Early diagnosis and treatment are crucial for preventing complications and improving outcomes.

Subacute Sclerosing Panencephalitis (SSPE) is a rare and progressive neurological disorder caused by the measles virus. It typically occurs several years after a person has had measles, and the symptoms can take several months to appear. The disease is characterized by a slow and progressive decline in mental and physical abilities, including memory loss, confusion, seizures, and muscle weakness. As the disease progresses, the symptoms become more severe and can lead to coma and death. There is no cure for SSPE, and treatment is focused on managing the symptoms and providing supportive care. The disease is preventable through vaccination against measles, which is highly effective in preventing SSPE and other complications of measles.

AIDS Dementia Complex (ADC) is a neurological disorder that occurs in people with advanced HIV/AIDS. It is characterized by a gradual decline in cognitive function, memory loss, confusion, and changes in personality. ADC is caused by the damage to the brain and nervous system that occurs as a result of HIV infection and the immune system's response to the virus. The symptoms of ADC can range from mild to severe and can affect a person's ability to perform daily activities. Treatment for ADC typically involves managing the underlying HIV infection and addressing the specific symptoms of the disorder.

Brain diseases refer to a wide range of medical conditions that affect the structure, function, or chemistry of the brain. These diseases can be caused by a variety of factors, including genetic mutations, infections, injuries, toxins, and degenerative processes. Some common examples of brain diseases include: 1. Alzheimer's disease: A progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. 2. Parkinson's disease: A movement disorder caused by the degeneration of dopamine-producing neurons in the brain. 3. Multiple sclerosis: An autoimmune disorder that affects the central nervous system, causing inflammation and damage to the myelin sheath that surrounds nerve fibers. 4. Huntington's disease: A genetic disorder that causes the progressive breakdown of nerve cells in the brain, leading to movement, cognitive, and psychiatric symptoms. 5. Epilepsy: A neurological disorder characterized by recurrent seizures, which can be caused by a variety of factors, including brain injury, genetic mutations, and brain tumors. 6. Stroke: A medical emergency caused by a disruption of blood flow to the brain, which can result in brain damage or death. 7. Brain tumors: Benign or malignant growths of abnormal cells in the brain that can cause a range of symptoms, depending on their location and size. These are just a few examples of the many different types of brain diseases that can affect people. Treatment options for brain diseases depend on the specific condition and its severity, and may include medications, surgery, physical therapy, and other interventions.

Demyelinating diseases are a group of neurological disorders characterized by the loss of the protective myelin sheath that surrounds nerve fibers in the central nervous system (CNS). The myelin sheath is essential for the proper functioning of the nervous system, as it allows electrical signals to travel quickly and efficiently along the nerve fibers. Demyelinating diseases can be classified into two main categories: primary and secondary. Primary demyelinating diseases, also known as idiopathic demyelinating diseases, are caused by an autoimmune response in which the body's immune system mistakenly attacks and destroys the myelin sheath. Examples of primary demyelinating diseases include multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), and neuromyelitis optica (NMO). Secondary demyelinating diseases, on the other hand, are caused by an underlying condition that damages the myelin sheath. Examples of secondary demyelinating diseases include chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), Guillain-Barré syndrome (GBS), and transverse myelitis. Symptoms of demyelinating diseases can vary widely depending on the specific disease and the location of the affected nerve fibers. Common symptoms include weakness, numbness, tingling, difficulty with coordination and balance, vision problems, and cognitive impairment. Treatment for demyelinating diseases typically involves medications to reduce inflammation and slow the progression of the disease, as well as physical therapy and other supportive measures to manage symptoms and improve quality of life.

Enterovirus infections are a group of viral infections caused by enteroviruses, which are a type of RNA virus that primarily affect the gastrointestinal tract and nervous system. These viruses are highly contagious and can be transmitted through contact with contaminated surfaces, bodily fluids, or respiratory droplets. Enterovirus infections can cause a range of symptoms, depending on the specific virus and the severity of the infection. Common symptoms include fever, headache, nausea, vomiting, diarrhea, and rash. In some cases, enterovirus infections can lead to more serious complications, such as meningitis, encephalitis, and paralysis. There is no specific treatment for enterovirus infections, as the viruses cannot be killed by antibiotics. Treatment typically involves managing symptoms and providing supportive care, such as fluids and pain relief. In severe cases, hospitalization may be necessary. Prevention of enterovirus infections involves practicing good hygiene, such as washing hands frequently and avoiding contact with infected individuals or surfaces. Vaccines are not currently available for all types of enteroviruses, but some vaccines are in development.

In the medical field, "Disease Models, Animal" refers to the use of animals to study and understand human diseases. These models are created by introducing a disease or condition into an animal, either naturally or through experimental manipulation, in order to study its progression, symptoms, and potential treatments. Animal models are used in medical research because they allow scientists to study diseases in a controlled environment and to test potential treatments before they are tested in humans. They can also provide insights into the underlying mechanisms of a disease and help to identify new therapeutic targets. There are many different types of animal models used in medical research, including mice, rats, rabbits, dogs, and monkeys. Each type of animal has its own advantages and disadvantages, and the choice of model depends on the specific disease being studied and the research question being addressed.

Autonomic Nervous System Diseases (ANSDs) refer to a group of disorders that affect the autonomic nervous system (ANS), which is responsible for regulating involuntary bodily functions such as heart rate, blood pressure, digestion, and breathing. The ANS is divided into two branches: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS). ANSDs can affect either or both branches of the ANS, leading to a range of symptoms and complications. Some common ANSDs include: 1. Multiple System Atrophy (MSA): a progressive disorder that affects the ANS, causing symptoms such as tremors, stiffness, and difficulty swallowing. 2. Parkinson's Disease: a neurodegenerative disorder that affects the ANS, leading to symptoms such as tremors, stiffness, and difficulty with balance and coordination. 3. Autonomic Failure: a group of disorders that affect the ANS, causing symptoms such as low blood pressure, dizziness, and fainting. 4. Postural Tachycardia Syndrome (POTS): a disorder that affects the ANS, causing symptoms such as rapid heart rate, dizziness, and fainting when standing up. 5. Orthostatic Hypotension: a disorder that affects the ANS, causing symptoms such as dizziness, fainting, and low blood pressure when standing up. Treatment for ANSDs depends on the specific disorder and its severity. In some cases, medications may be used to manage symptoms, while in other cases, lifestyle changes or surgery may be necessary.

Lamin Type A is a type of protein that is found in the nuclear lamina, a mesh-like structure that surrounds the nucleus of a cell. The nuclear lamina plays a crucial role in maintaining the shape and integrity of the nucleus, as well as in regulating gene expression and DNA replication. Lamin Type A is synthesized in the endoplasmic reticulum and then transported to the nucleus, where it is assembled into a filamentous network that forms the nuclear lamina. Lamin Type A is also involved in the formation of interphase chromatin fibers, which help to organize and compact the DNA within the nucleus. Mutations in the gene that encodes Lamin Type A can lead to a group of genetic disorders known as laminopathies, which are characterized by a range of symptoms including muscle weakness, bone deformities, and developmental delays. These disorders are caused by defects in the structure or function of the nuclear lamina, which can disrupt normal cellular processes and lead to tissue damage and dysfunction.

Digestive system diseases refer to a group of medical conditions that affect the organs and structures involved in the digestion and absorption of food. These diseases can affect any part of the digestive system, including the mouth, esophagus, stomach, small intestine, large intestine, rectum, anus, liver, gallbladder, pancreas, and bile ducts. Some common digestive system diseases include: 1. Gastroesophageal reflux disease (GERD) 2. Peptic ulcers 3. Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis 4. Irritable bowel syndrome (IBS) 5. Diverticulitis 6. Appendicitis 7. Pancreatitis 8. Cholecystitis 9. Hepatitis 10. Cirrhosis 11. Colorectal cancer 12. Celiac disease 13. Malabsorption syndromes, such as lactose intolerance and celiac disease. These diseases can cause a range of symptoms, including abdominal pain, bloating, nausea, vomiting, diarrhea, constipation, and weight loss. Treatment for digestive system diseases depends on the specific condition and may include medications, dietary changes, lifestyle modifications, and in some cases, surgery.

Peripheral nervous system diseases refer to disorders that affect the peripheral nerves, which are the nerves that carry signals from the brain and spinal cord to the rest of the body. These diseases can affect the nerves themselves or the tissues surrounding them, and can result in a range of symptoms, including pain, numbness, weakness, and tingling. Some examples of peripheral nervous system diseases include: 1. Charcot-Marie-Tooth disease: A group of inherited disorders that affect the nerves in the hands and feet, causing weakness, numbness, and loss of sensation. 2. Guillain-Barre syndrome: A rare autoimmune disorder in which the body's immune system attacks the peripheral nerves, causing weakness and paralysis. 3. Peripheral neuropathy: A general term for any disorder that affects the peripheral nerves, which can be caused by a variety of factors, including diabetes, alcoholism, and exposure to certain toxins. 4. Multiple sclerosis: An autoimmune disorder that affects the central nervous system, including the brain and spinal cord, but can also affect the peripheral nerves, causing symptoms such as numbness and weakness. 5. Amyotrophic lateral sclerosis (ALS): A progressive neurodegenerative disorder that affects the nerves controlling muscle movement, leading to weakness and paralysis. Treatment for peripheral nervous system diseases depends on the specific disorder and its underlying cause. In some cases, medications or physical therapy may be used to manage symptoms, while in other cases, surgery or other interventions may be necessary.

Central Nervous System (CNS) neoplasms are tumors that develop in the brain or spinal cord. These tumors can be either benign (non-cancerous) or malignant (cancerous). CNS neoplasms can affect any part of the brain or spinal cord, including the brainstem, cerebellum, and spinal cord. The symptoms of CNS neoplasms can vary depending on the location and size of the tumor. Common symptoms include headaches, seizures, changes in vision or hearing, difficulty with balance or coordination, and changes in personality or behavior. Diagnosis of CNS neoplasms typically involves a combination of imaging tests, such as MRI or CT scans, and a biopsy to confirm the presence of a tumor. Treatment options for CNS neoplasms may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. CNS neoplasms can be challenging to treat because they are often located in critical areas of the brain or spinal cord, and because they can be difficult to completely remove without causing damage to surrounding healthy tissue. However, with appropriate treatment and management, many people with CNS neoplasms are able to live long and fulfilling lives.

Immune system diseases refer to a group of disorders that affect the body's immune system, which is responsible for defending the body against infections and diseases. These diseases can be caused by a variety of factors, including genetic mutations, infections, autoimmune disorders, and exposure to certain chemicals or toxins. Some common examples of immune system diseases include: 1. Autoimmune diseases: These are disorders in which the immune system attacks healthy cells and tissues in the body. Examples include rheumatoid arthritis, lupus, and multiple sclerosis. 2. Infections: Certain infections can weaken the immune system, making the body more susceptible to other infections. Examples include HIV/AIDS and tuberculosis. 3. Immunodeficiency disorders: These are conditions in which the immune system is unable to function properly, leaving the body vulnerable to infections and diseases. Examples include severe combined immunodeficiency (SCID) and common variable immunodeficiency (CVID). 4. Allergies: While allergies are not strictly immune system diseases, they involve an overactive immune response to harmless substances, such as pollen or certain foods. Treatment for immune system diseases depends on the specific disorder and its severity. In some cases, medications may be used to suppress the immune system or to treat symptoms. In other cases, lifestyle changes or alternative therapies may be recommended.

Endocrine system diseases refer to disorders that affect the endocrine glands and the hormones they produce. The endocrine system is responsible for regulating various bodily functions, including growth and development, metabolism, and reproduction. Endocrine system diseases can be classified into two main categories: endocrine disorders and endocrine tumors. Endocrine disorders are conditions in which the endocrine glands produce too much or too little of a hormone, leading to imbalances in the body's chemical processes. Examples of endocrine disorders include diabetes, thyroid disorders, and Cushing's syndrome. Endocrine tumors, on the other hand, are abnormal growths of cells in the endocrine glands. These tumors can produce too much or too little of a hormone, leading to similar symptoms as endocrine disorders. Examples of endocrine tumors include pituitary adenomas, thyroid nodules, and adrenal gland tumors. Endocrine system diseases can have a significant impact on a person's quality of life and can lead to serious health complications if left untreated. Treatment options for endocrine system diseases depend on the specific condition and may include medication, surgery, or other therapies.

Nervous system neoplasms refer to tumors or abnormal growths that develop in the nervous system, which includes the brain, spinal cord, and nerves. These neoplasms can be either benign (non-cancerous) or malignant (cancerous) and can affect any part of the nervous system. The nervous system is responsible for transmitting signals throughout the body, controlling movement, sensation, and thought. When a neoplasm develops in the nervous system, it can disrupt these functions and cause a range of symptoms, depending on the location and size of the tumor. Some common symptoms of nervous system neoplasms include headaches, seizures, changes in sensation or movement, difficulty speaking or swallowing, and changes in behavior or personality. Diagnosis typically involves imaging tests such as MRI or CT scans, as well as a biopsy to confirm the presence of a tumor. Treatment for nervous system neoplasms depends on the type, location, and size of the tumor, as well as the patient's overall health. Options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. In some cases, a watchful waiting approach may be appropriate if the tumor is small and not causing symptoms.

Central nervous system disease Peripheral neuropathy "Nervous System Diseases - Neurologic Diseases". MedlinePlus. Retrieved ... Nervous system diseases, also known as nervous system or neurological disorders, refers to a small class of medical conditions ... Some nervous system diseases are due to genetic mutations. For example, Huntington's disease is an inherited disease ... "Central nervous system: Structure, function, and diseases". Medical News Today. 22 December 2017. "Central nervous system: ...
Neurodegenerative disease List of central nervous system infections "Nervous System Diseases". Healthinsite.gov.au. Retrieved ... Central nervous system diseases, also known as central nervous system disorders, are a group of neurological disorders that ... Catalepsy is considered a symptom of serious diseases of the nervous system (e.g., Parkinson's disease, Epilepsy, etc.) rather ... Brain degeneration also causes central nervous system diseases (i.e. Alzheimer's, Parkinson's, and Huntington's diseases). ...
California encephalitis virus Central nervous system viral disease Cytomegalovirus encephalitis SARS-CoV-2 Eastern equine ... with 22 of these being replicated with the UK Biobank and not all of them necessarily central nervous system viral diseases) ... and can invade the mammalian system by spreading into the peripheral nervous system and more rarely the CNS. CNS is protected ... List of central nervous system infections Aging brain § Immune system and fluids "Neurological Infections". University of ...
Autoimmune diseases, Central nervous system disorders, Idiopathic diseases). ... "Inflammatory demyelinating diseases of the central nervous system". Neuropathology. Handbook of Clinical Neurology. Vol. 145. ... Lebrun C, Kantarci OH, Siva A, Pelletier D, Okuda DT (February 2018). "Anomalies Characteristic of Central Nervous System ... Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural ...
"A Manual of Diseases of the Nervous System". The Journal of Nervous and Mental Disease. 14 (2): 123. February 1887. ISSN 0022- ... A Manual of Diseases of the Nervous System, also known as the 'Bible of Neurology', is a medical textbook by William Gowers. It ... "A manual of diseases of the nervous system / by W.R. Gowers". Wellcome Collection. Retrieved 10 June 2023. "A Manual of the ... Diseases of the Nervous System". Journal of the American Medical Association. XXI (25): 950. 16 December 1893. doi:10.1001/jama ...
This is a shortened version of the sixth chapter of the ICD-9: Diseases of the Nervous System and Sense Organs. It covers ICD ... sclerosis 341 Other demyelinating diseases of central nervous system 341.0 Neuromyelitis optica 341.1 Schilder's disease 341.8 ... Infectious and parasitic diseases. However, as it results in a disorder of the nervous system, it is also listed in this ... 349 Other and unspecified disorders of the nervous system 349.0 Reaction to spinal or lumbar puncture 349.1 Nervous system ...
Multiple sclerosis and other demyelinating diseases of the central nervous system (CNS) produce lesions (demyelinated areas in ... "Demyelinating diseases of the central nervous system". Medicine. 11 (77): 4601-4609. doi:10.1016/j.med.2015.04.001. Poser C. M ... However, in a person with MS, these cells recognize healthy parts of the central nervous system as foreign and attack them as ... Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural ...
At that time it became the Hospital for Epilepsy and Paralysis and Other Diseases of the Nervous System, Maida Vale. It became ... It moved to Portland Terrace in 1872, becoming the Hospital for Diseases of the Nervous System in 1873 and the Hospital for ... "Maida Vale Hopital [sic] for Nervous Diseases". National Archives. Retrieved 8 July 2018. v t e v t e (Use dmy dates from April ... The Maida Vale Hospital for Nervous Diseases was a hospital that existed in west London from 1867 to 1993. The hospital was ...
"Aqueductal Stenosis". Nervous System Diseases. Retrieved 15 October 2013. Cinalli, G.; Spennato, P.; Nastro, A.; Aliberti, F.; ... Childs Nervous System. 27 (10): 1621-42. doi:10.1007/s00381-011-1546-2. PMID 21928028. Spennato, P; S. Tazi; O. Bekaert; G. ... Child's Nervous System. 11 (3): 180-5. doi:10.1007/BF00570262. PMID 7773981. "Hydrocephalus Fact Sheet". National Institute of ... This disease is transmitted from mother to son. This disorder is caused by a point mutation in the gene for neural cell ...
"Primary Generalized Epilepsy". Nervous-system-diseases.com. 2013-09-09. Retrieved 2016-12-16. "Seizures or epilepsy". ...
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Diseases of the nervous system. Boericke & Runyon. p. 296. Retrieved 5 December 2017. Infantile progressive bulbar palsy. Piña- ... The disease exists in both rapid and slow onsets, and involves inflammation of the gray matter of the bulb. Infantile PBP is a ... Articles with short description, Short description matches Wikidata, Motor neuron diseases). ... disease that manifests itself in two forms: Fazio-Londe syndrome (FL) and Brown-Vialetto-Van Laere syndrome (BVVL). Wilson, ...
Ajax ET (October 1966). "An unusual case of primidone intoxication". Diseases of the Nervous System. 27 (10): 660-661. PMID ... Monroe RR (February 1975). "Anticonvulsants in the treatment of aggression". The Journal of Nervous and Mental Disease. 160 (2- ... Dupuytren's contracture, a disease of the fasciae in the palm and fingers that permanently bends the fingers (usually the ... In any case, the use of more than one anticonvulsant has been associated with an increased prevalence of bone disease in ...
Diseases of the Nervous System. 29 (5): Suppl:147-Suppl:152. PMID 5673619. Retrieved 2 July 2022. Walther DJ, Peter JU, ... Until the discovery of TPH2 in 2003, serotonin levels in the central nervous system were believed to be regulated by serotonin ... gain insights into the functions of serotonin systems more broadly (such as hypersexuality in rodents as well as increased ... 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including ...
Diseases of the nervous system. 15 (7): 218-20. PMID 13182975. Cohen, Harvey D.; Rosen, Raymond C.; Goldstein, Leonide (May ... Chapter "Nervous system") (in Russian) Abram Svyadoshch. Женская сексопатология (Female sexopathology). - 3-е изд., перераб. и ... Experienced by males and females, orgasms are controlled by the involuntary or autonomic nervous system. They are usually ... Psychoanalytic theory mistook these artificial secondary drives for primary, natural functions." "Nervous System: A Tutorial ...
Revitch, E (1965). "Sex murder and the potential sex murderer". Diseases of the Nervous System. 26 (10): 640-648. PMID 5831700 ...
Sontheimer, Harald (2015). Diseases of the Nervous System. Academic Press. p. 170. ISBN 978-0-12-800403-6. Archived from the ... It is not clear exactly how many repeat units are needed to cause disease. SOD1, which codes for superoxide dismutase 1, is the ... In 2016, it was observed that mutations in the TBK1 protein contributed to formation of the disease. Since the TBK1 protein is ... ALS has an oligogenic mode of inheritance, meaning that mutations in two or more genes are required to cause disease. C9orf72 ...
Diseases of the nervous system --> Tic disorders: "onset during the developmental period" Ueda K, Black KJ (2021). "Recent ... Tourette syndrome is classified as a disease of the nervous system and a neurodevelopmental disorder, and only one motor tic is ... are classified in the ICD-11 chapter on diseases of the nervous system, but are cross-listed in the grouping of ... If there is a family history of liver disease, serum copper and ceruloplasmin levels can rule out Wilson's disease. The typical ...
He published Diseases of the Nervous System in 1912. He was a fine runner in his youth and a keen golfer up to his death at the ... Bury, J. S. (30 April 1904). "An Address on Trauma in Relation to Disease of the Nervous System: Presidential Address to the ... Diseases of the nervous system. CIHM/ICMH collection de microfiches ;no. 77911. Macmillan. 1912. ISBN 9780665779114. "Obituary ... Bury, Judson S. (9 November 1901). "The Bradshaw Lecture on Prognosis in Relation to Disease of the Nervous System: Delivered ...
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Diseases of the Nervous System. 21(3)Suppl (3 Suppl): 120-123. PMID 13832091. Sacerdoti G (1960). "[First clinical experiences ... 1st US drug for Huntington's disease wins approval[dead link] Jankovic J, Beach J (1997). "Long-term effects of tetrabenazine ... Although other drugs had been used "off label," tetrabenazine was the first approved treatment for Huntington's disease in the ... Tetrabenazine is used as a treatment, but not as a cure, for hyperkinetic disorders such as: Huntington's disease - ...
Wilson, John Eastman (1909). "Diseases affecting the spinal grey-matter". Diseases of the nervous system. Boericke & Runyon. ( ... Brown CH (1894). "Infantile amyotrophic lateral sclerosis of the family type". Journal of Nervous and Mental Disease. 21 (2): ... Syndromes affecting the nervous system, Syndromes affecting hearing, Rare syndromes). ... variability in age at onset and disease progression highlighting the phenotypic overlap with Fazio-Londe disease". Brain & ...
Schuckit, M. A.; Winokur, G. A. (1972). "A short-term followup of women alcoholics". Diseases of the Nervous System. 33 (10): ... However, Huss regarded heavy drinking still as a vice (that causes a destruction of the nervous system). Moreover, this came ... The modern disease theory of alcoholism states that problem drinking is sometimes caused by a disease of the brain, ... Disease model of addiction "Neuropathology". American Medical Association. Retrieved 4 October 2020. "Understanding the Disease ...
Journal of Central Nervous System Disease. 3: 179-87. doi:10.4137/JCNSD.S4888. PMC 3663619. PMID 23861647. Bialer M, Soares-da- ...
Wood-allum, Clare A.; Shaw, Pamela J. (2014). "Thyroid disease and the nervous system". Neurologic Aspects of Systemic Disease ... non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder ... "nervous system" and -pathy, "disease of") without modifier usually means peripheral neuropathy. Neuropathy affecting just one ... immune system disease, celiac disease, non-celiac gluten sensitivity, or viral infection. It can also be genetic (present from ...
Journal of Central Nervous System Disease. 3: JCNSD.S4138. doi:10.4137/JCNSD.S4138. PMC 3663608. PMID 23861634. Nicolson SE, ... American Society of Health-System Pharmacists. Retrieved May 8, 2019. "Product Information: Zeldox IM (ziprasidone mesilate)". ... Nemeroff CB (December 2007). "Ziprasidone in the treatment of mania in bipolar disorder". Neuropsychiatric Disease and ...
Journal of Central Nervous System Disease. 3: 51-65. doi:10.4137/JCNSD.S1611. PMC 3663615. PMID 23861638. Anttila AK, Rasanen L ... Central Nervous System Agents in Medicinal Chemistry. 9 (3): 197-204. doi:10.2174/1871524910909030197. PMID 20021354. Hindmarch ... There is tentative evidence fluvoxamine might be useful for reducing COVID-19 disease severity if given as an early treatment. ... Kroon LA (September 2007). "Drug interactions with smoking". American Journal of Health-System Pharmacy. 64 (18): 1917-21. doi: ...
Mawdsley C (December 1975). "Diseases of the central nervous system. Involuntary movements". Br. Med. J. 4 (5996): 572-4. doi: ... Hammond and described in his book Diseases of the Nervous System in 1871. Hammond was also the person who created the term " ... Athetosis is characterized as a symptom that is present in many forms of central nervous system disorders that affect the body ... Athetosis is a commonly occurring symptom in the disease cerebral palsy. Of all people with the disease, between 16% and 25% of ...
"Lysine methylation regulates nervous system diseases". Neuropeptides. 76: 101929. doi:10.1016/j.npep.2019.04.004. PMID 31076097 ...
Journal of Central Nervous System Disease. 3: 51-65. doi:10.4137/JCNSD.S1611. PMC 3663615. PMID 23861638. McGechan A, ... Neubauer DN (February 2008). "A review of ramelteon in the treatment of sleep disorders". Neuropsychiatric Disease and ... American Journal of Alzheimer's Disease and Other Dementias. 30 (2): 119-129. doi:10.1177/1533317514539379. PMID 24946785. ...
Learn about neurologic diseases, including their symptoms, causes, and treatments. ... Your nervous system includes your brain, spinal cord, and nerves. ... Article: Hospitalisations related to nervous-system diseases in Australia, 1998-2019: a secular trend... ... Degenerative diseases, where nerve cells are damaged or die, such as Parkinsons disease and Alzheimers disease ...
Raccoon Roundworm Infection Associated with Central Nervous System Disease and Ocular Disease - Six States, 2013-2015. Weekly ... Raccoon Roundworm Infection Associated with Central Nervous System Disease and Ocular Disease - Six States, 2013-2015. MMWR ... including six cases of central nervous system disease and one of ocular disease. Laboratory and clinical information for each ... which is often found in Baylisascaris procyonis central nervous system disease (8). In the single case of ocular larva migrans ...
... in advancing innovative testing strategies are helping to change the future outlook for people with degenerative diseases. ... The diagnosis of central nervous system disease is largely based on clinical symptoms and cognitive testing. More recent ... The central nervous system (CNS) is a complex, sophisticated network of neurons that includes our brain and spinal cord. It ... One of the most common impairments of the nervous system is degeneration - the progressive loss in function or death of neurons ...
Diagnostic Challenges of Central Nervous System Tuberculosis. Emerging Infectious Diseases. 2008;14(9):1473-1475. doi:10.3201/ ... Tuberculosis of the central nervous system. Postgrad Med J. 1999;75:133-40.PubMedGoogle Scholar ... Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California ... Tuberculosis (TB) of the central nervous system (CNS) is classically described as meningitis. However, altered mental status, ...
Infectious Disease in the Central Nervous System and Therapeutic Strategies to Cross the Blood-Brain Barrier. The page you are ...
... has been found to be effective in treatment of many different nervous system disorders and conditions. And it may be effective ... Nervous System Diseases and IPT. Without the nervous system we are meat, organs, bones, and sinew. The nervous system is our ... Immune System. Allergies. Nervous System. Skin. Digestive. Genitourinary. MusculoSkeletal. End of Life. Veterinary. ... It was the nervous system that Dr. Perez Garcia 1 first treated with IPT. The nervous system wracked with tertiary syphilis, ...
FDAs Peripheral and Central Nervous System Drugs Advisory Committee Regarding Aducanumab for Treatment of Alzheimers Disease ... In testimony before a meeting of the Food and Drug Administrations (FDAs) Peripheral and Central Nervous System Drugs ... Public Citizen urged the committee to recommend that the FDA not approve aducanumab for treatment of Alzheimers disease ...
... chronic obstructive pulmonary disease, asthma, diseases of the nervous system, endocrinal disorders, congenital heart disease) ... Effect of yogic intervention on the autonomic nervous system in the patients with coronary artery disease: a randomized ... Effect of yogic intervention on the autonomic nervous system in the patients with coronary artery disease: a randomized ... Autonomic failure: a text book of clinical disorders of the autonomic nervous system. Oxford, Oxford University Press, 1992:312 ...
Archives for Central Nervous System Inflammatory Demyelinating Diseases. Central Nervous System Inflammatory Demyelinating ... Diseases. Melissa Parks, MSN, NP-C. May 19, 2023. Melissa Parks, MSN, NP-C, is an advanced practice provider at Hamilton ... including the treatment of Alzheimers and Parkinsons disease, seizure disorders, and strokes. ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
... tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, co ... An accelerated model of human immunodeficiency virus central nervous system disease was developed in which more than 90% of ... Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an ... Tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an accelerated, consistent ...
Diseases of nervous system and sense organs, number of deaths, by sex, Categories: Diseases of blood, endocrine, nervous ... Diseases of nervous system and sense organs, number of deaths, female (Line chart) ... Diseases of nervous system and sense organs, number of deaths, male (Line chart) ... Diseases of nervous system and sense organs, number of deaths (Line chart) ...
... causes a wide variety of diseases in humans. A ubiquitous organism, S pyogenes is the most common bacterial cause of acute ... Central nervous system diseases. The primary evidence for poststreptococcal autoimmune central nervous system (CNS) disease is ... National Center for Immunization and Respiratory Diseases: Division of Bacterial Diseases. Group A Streptococcal (GAS) Disease ... Post-streptococcal autoimmune disorders of the central nervous system. Curr Opin Neurol. 2003 Jun. 16(3):359-65. [QxMD MEDLINE ...
Autoimmune disease antibody attacking my brain and nervous system... Posted by longislandswag23 @longislandswag23, May 24 3: ... After numerous blood tests they found an antibody attacking my nervous system and brain they said.. They then did 2 lumbar ... Autoimmune diseases can be very nebulous with symptoms that come and go. I went to the ER multiple times before I got a ... Autoimmune diseases can be very nebulous with symptoms that come and go. I went to the ER multiple times before I got a ...
Syphilitic infection of the nervous system results in the most chronic, insidious meningeal inflammatory process known. ... Syphilis is a sexually transmitted disease caused by Treponema pallidum, with human beings as the only host. ... Spirochetal diseases of the nervous system. Curr Opin Neurol. 1994 Jun. 7(3):217-22. [QxMD MEDLINE Link]. ... Syphilitic infection of the nervous system results in the most chronic, insidious meningeal inflammatory process known. ...
Congenital Heart Disease and Risk of Central Nervous System Infections: A Nationwide Cohort Study.. Bagge, Carina N; Smit, ... Congenital heart disease (CHD) is associated with risk factors of central nervous system (CNS) infections including infective ...
Role of thrombin in central nervous system injury and disease. Nathan A. Shlobin*, Meirav Har-Even*, ZeEv Itsekson-Hayosh, ... Dive into the research topics of Role of thrombin in central nervous system injury and disease. Together they form a unique ... Role of thrombin in central nervous system injury and disease. / Shlobin, Nathan A.; Har-Even, Meirav; Itsekson-Hayosh, ZeEv ... Role of thrombin in central nervous system injury and disease. Biomolecules. 2021 Apr;11(4):562. doi: 10.3390/biom11040562 ...
Other specified degenerative diseases of nervous system. G31.9. Degenerative disease of nervous system, unspecified. ... Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere. K92.9. Disease of digestive system, ... When reported reason was a symptom due to an underline disease, a disease code was used (e.g., I51.9 for fluid retention due to ... When reported reason was for disease prevention, an appropriate ICD-10-CM code followed by a letter "P" was used. (e.g., A49.9P ...
... diseases of the liver, vision, skin and immune system. ... of AFM-Telethon concern neurological and neuromuscular diseases ... Rare diseases of the brain and nervous system *Multiple sclerosis. A pilot phase I clinical trial to assess the effects of cell ... Rare diseases of the immune system *Artemis deficiency. The preclinical development of a gene therapy product aims to express ... Drugs in development or marketed with the support of AFM-Telethon concern neurological and neuromuscular diseases, diseases of ...
CDC WONDER is a system for disseminating Public Health data and information ... Diseases of Central Nervous system , Encephalitis , Encephalomyelitis , Epilepsy , Mastoiditis , Menieres disease , Meningitis ... disease, cerebrovascular disease, arteriosclerosis, other diseases of the circulating system ... Other disease of the circulatory system Aortic aneurysm Arterial embolism and thrombosis Buergers disease Chilblains ...
... diseases of the circulatory system (7.8%), and diseases of the nervous system (6.6%). Relative proportions of these outcomes ... Circulatory system; Nervous system disorders; Diseases; Author Keywords: Agriculture; disability; disease; farmer; gender; ... Almost half of the outcomes (44.6%) were primarily related to diseases of the musculoskeletal system (MSDs). Other common ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ...
Teens rare disease disconnects brain from nervous system. DALLAS One year ago, 13-year-old… More ... Central Nervous System Therapeutic Targets in Friedreich Ataxia. Ian H. Harding, PhD, David R. Lynch,… More ... Mapping the anatomical and functional connectivity of the Central Nervous System in Friedreichs Ataxia using Magnetic ... Tampa at center of research to cure rare disease. Tampa, Florida - Its a disease that… More ...
Understanding the causes and types of demyelinating disease, such as multiple sclerosis, can help guide treatment decisions and ... is the most common demyelinating disease of the central nervous system. In this disorder, your immune system attacks the myelin ... What types of demyelinating disease affect the central nervous system, and what can you do about them?. Answer From Jerry W. ... Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) - inflammatory disorder of the central nervous system, ...
Categories: Nervous System Diseases Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, ... The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. ... Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People ...
Nervous System - Structure, Functions, Diseases. The nervous system is a functional set of various interconnected nervous ... The brain is the anterior part of the central nervous system, which is based on a nerve cell. Located inside the skull ... Liver - Structure, Functions, Diseases, Treatment, Cleansing. The liver is one of the largest organs in the human body and ... Eyes - Functions, Diseases, Treatment, Vision Examination And Correction. The eyes are a sensory organ of a person, from where ...
Provided by the Centers for Disease Control and Prevention (CDC). ... Distinct systemic and central nervous system disease patterns ... The Centers for Disease Control and Prevention (CDC) protects peoples health and safety by preventing and controlling diseases ... There are four species, of which only PeV-A is known to cause disease in humans. PeV-A has multiple types; PeV-A3 is most often ... The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to inform ...
Facial nerve paralysis is a common, but usually self-limited form of disease. Other manifestations are usually chronic and ... Central Nervous System Diseases / diagnosis* * Central Nervous System Diseases / drug therapy* * Chronic Disease ... Results: Neurological disease was identified in 71 of 554 patients with sarcoidosis. Seventh (facial) cranial nerve paralysis ... Evaluation for neurological disease included routine physical examination. Magnetic resonance imaging, cerebral spinal fluid ...
  • Possible treatment for Alzheimer's disease and other neurodegenerative diseases ( Parkinson's disease , Huntington's disease , etc. (iptq.com)
  • He has joined Juan Gonzalez, MD , at HPG-Neurology and diagnoses and treats issues related to the brain, spinal cord, nerves and muscles, including the treatment of Alzheimer's and Parkinson's disease, seizure disorders, and strokes. (hamiltonhealth.com)
  • Other disorders that are associated with a damaged nerve system include Alzheimer's disease and Parkinson's disease . (medicalnewstoday.com)
  • This could lead to improvements in ischemic stroke, Parkinson's disease, Alzheimer's disease, and depression. (medicalnewstoday.com)
  • Although research in the early stages, accumulated evidence suggests that some culinary-medicinal mushrooms, including lion's mane, may play an important role in the prevention of many neurological dysfunctions - including Parkinson's and Alzheimer's diseases - by reducing chemicals known to cause brain damage. (medicalnewstoday.com)
  • Dementia is not a specific disease but is rather a general term for the impaired ability to remember, think, or make decisions that interferes with doing everyday activities. (roche.com)
  • Advances in biomarker testing, a growing number of dementia-inclusive communities, and open clinical trials for conditions like Alzheimer's disease are transforming future outlooks. (roche.com)
  • The nervous system wracked with tertiary syphilis, causing dementia and paralysis. (iptq.com)
  • Accumlating evidence have suggested that diabetes mellitus links dementia, notably of Alzheimer's disease (AD). (nature.com)
  • Pathogenetic mechanisms and medical behaviours which can improve health in patients with dementia, Parkinson disease and motoneuron diseases" scientific coordinator: C. Caltagirone. (unibo.it)
  • The autonomic nervous system--a role in sudden infant death syndrome. (bmj.com)
  • In this review, we explore the mechanisms of thrombin action, localization, and functions in the central nervous system and describe the involvement of thrombin in stroke and intracerebral hemorrhage, neurodegenerative diseases, epilepsy, traumatic brain injury, and primary central nervous system tumors. (tau.ac.il)
  • Drugs in development or marketed with the support of AFM-Telethon concern neurological and neuromuscular diseases, diseases of the liver, vision, skin and immune system. (afm-telethon.fr)
  • Almost half of them concern neuromuscular diseases, the other concern rare diseases. (afm-telethon.fr)
  • We aim to comprehensively characterize the role of thrombin in neurological disease and injury. (tau.ac.il)
  • Evaluation for neurological disease included routine physical examination. (nih.gov)
  • Neurological disease was identified in 71 of 554 patients with sarcoidosis. (nih.gov)
  • Cysticercosis of the central nervous system is the most important neurological disease of parasitic origin in humans. (who.int)
  • Autoimmune disease antibody attacking my brain and nervous system. (mayoclinic.org)
  • Although the exact cause is unknown, it's considered an autoimmune disease. (medicinenet.com)
  • Because the exact antigen or target of the immune-mediated attack is not known, many experts prefer to label multiple sclerosis as 'immune-mediated instead of an autoimmune disease. (medicinenet.com)
  • Baylisascariasis is not a nationally notifiable disease in the United States, and little is known about how commonly it occurs or the range of clinical disease in humans. (cdc.gov)
  • Infection with Streptococcus pyogenes , a beta-hemolytic bacterium that belongs to Lancefield serogroup A, also known as the group A streptococci (GAS), causes a wide variety of diseases in humans. (medscape.com)
  • Parechoviruses are a group of viruses known to cause a spectrum of disease in humans. (cdc.gov)
  • There are four species, of which only PeV-A is known to cause disease in humans. (cdc.gov)
  • Similarly, direct injection of viruses into the cerebrospinal fluid (e.g., via lumbar puncture in humans) also permits targeting of the peripheral (PNS) and central nervous systems (CNS). (frontiersin.org)
  • Understandably, researchers are scrambling to shed light on the devastating impact that the disease has on humans, leaving the great apes hidden in the dark. (listverse.com)
  • Concurrent culture positive pulmonary disease was found in 4 (50%) of 8 patients tested. (cdc.gov)
  • 44. Pulmonary disease is diagnosed. (medscape.com)
  • These eggs then develop into cysticerci which migrate mostly into muscle (causing cysticercosis) and into the central nervous system where the cysticerci can cause seizures and many other neurological symptoms (cysticercosis of the central nervous system). (who.int)
  • Conversely, a study in Honduras reported in 1999 showed that when a diagnosis of cysticercosis of the central nervous system had been made, seizures were the presenting symptom in 52% of cases. (who.int)
  • The diagnosis of cysticercosis of the central nervous system involves the interpretation of non-specific clinical manifestations, such as seizures, often with characteristic findings on computed tomography or magnetic resonance imaging of the brain, and the use of specific serological tests. (who.int)
  • As the disease crawls through the nervous system, seizures and paralysis occur. (listverse.com)
  • Alzheimer's disease remains one of society's greatest public health challenges, costing an estimated USD 818 billion (1.1% of the global GDP)1 and placing immeasurable burden on patients and their loved ones. (roche.com)
  • Characteristics of patients misdiagnosed with Alzheimer's disease and their medication use: an analysis of the NACC-UDS database. (roche.com)
  • In testimony before a meeting of the Food and Drug Administration's (FDA's) Peripheral and Central Nervous System Drugs Advisory Committee, Public Citizen urged the committee to recommend that the FDA not approve aducanumab for treatment of Alzheimer's disease because there is not substantial evidence of effectiveness. (citizen.org)
  • The optogenetic activation of hippocampal astrocytes can be viewed as a novel therapeutic avenue for addressing Alzheimer's disease. (medindia.net)
  • In Alzheimer's disease condition, the control and adjustment of ABCA7 levels in response to inflammation and the decrease in the availability of cholesterol. (medindia.net)
  • Senses of smell and taste returned, vertigo and tinnitus eliminated, and hearing and sight improved, by treatment of circulatory and other systems. (iptq.com)
  • The immune system of a person with MS attacks the protective layer which surrounds the nerves. (medicalnewstoday.com)
  • Research is ongoing into developing new medications, immune system modifications, and other ways to identify potential causes of MS. (medicinenet.com)
  • Multiple sclerosis is a disease that involves an immune-mediated process that results in an abnormal response in the body's immune system that damages central nervous system (CNS) tissues in which the immune system attacks myelin, the substance that surrounds and insulates nerve fibers causing demyelination that leads to nerve damage. (medicinenet.com)
  • The diagnosis of central nervous system disease is largely based on clinical symptoms and cognitive testing. (roche.com)
  • Autoimmune diseases can be very nebulous with symptoms that come and go. (mayoclinic.org)
  • other tests may be done to rule out other diseases that may cause similar symptoms. (medicinenet.com)
  • All had been diagnosed with coronary artery disease. (who.int)
  • 0.05), i.e. a significant positive effect was observed when yoga therapy was used as an adjunct in patients with coronary artery disease. (who.int)
  • And IPT probably carries out all these functions in the peripheral nervous system as well. (iptq.com)
  • During May 2013-December 2015, seven cases of baylisascariasis not already described in the literature were identified among patients in the United States through testing at CDC, including six cases of central nervous system disease and one of ocular disease. (cdc.gov)
  • An accelerated model of human immunodeficiency virus central nervous system disease was developed in which more than 90% of infected macaques develop typical simian immunodeficiency virus (SIV) encephalitis with neuronal dysfunction by postinoculation (pi) day 84. (eurekamag.com)
  • 53. Central nervous system disease is diagnosed. (medscape.com)
  • There are more than 600 neurologic diseases. (medlineplus.gov)
  • Infection can result in fatal human disease or severe neurologic outcomes if it is not treated rapidly. (cdc.gov)
  • Although raccoons are typically asymptomatic when infected with the parasite, the larval form of Baylisascaris procyonis can result in fatal human disease or severe neurologic outcomes if not treated rapidly. (cdc.gov)
  • 45. Cardiovascular disease is diagnosed. (medscape.com)
  • scholarship on "Effects of snoring and obstructive sleep apneas on attention and supervision and on the cardiovascular system" delivered by the Consortium for the management of the clinic for nervous and mental diseases, University of Bologna. (unibo.it)
  • Diagnosis and treatment of the disease is complex and requires specifically skilled staff. (who.int)
  • Facial nerve paralysis is a common, but usually self-limited form of disease. (nih.gov)
  • In advanced stages, sleeping sickness attacks the central nervous system causing confusion, irritability, sensory disturbances, difficulty walking and talking, and disturbances of the sleep cycle, which gives the disease its name. (who.int)
  • This amount exceeds the individual cost of cancer, coronary heart disease, stroke, and diabetes. (cdc.gov)
  • Sleeping sickness is a vector-borne parasitic disease that is capable of causing explosive outbreaks particularly in remote areas. (who.int)
  • Human African trypanosomiasis, also known as sleeping sickness, is a vector-borne parasitic disease. (who.int)
  • An understanding of the diverse nature of infectious disease complications attributable to this organism is an important cornerstone of pediatric medicine. (medscape.com)
  • Children and teenagers can have MS (pediatric MS). It is estimated that about 8,000 to 10,000 children and teens up to 18 years old have been diagnosed with pediatric MS. Moreover, an additional 10,000 to 15,000 children and teens have had at least one symptom of the disease. (medicinenet.com)
  • From informing lifestyle changes that could help to slow the decline in cognitive functions to optimizing treatment, biomarker testing is opening new opportunities for people with CNS disease. (roche.com)
  • Measuring changes in biomarkers can help us to understand how quickly a person's disease is advancing - and, potentially, predict how it may develop in the future. (roche.com)
  • Almost half of the outcomes (44.6%) were primarily related to diseases of the musculoskeletal system (MSDs). (cdc.gov)
  • Virus-mediated gene therapy has the potential to deliver exogenous genetic material into specific cell types to promote survival and counteract disease. (frontiersin.org)
  • With thousands of clinical trials to date, gene therapy is a flourishing strategy with great promise for the treatment of diseases impacting the nervous system. (frontiersin.org)
  • One of the promising features of IPT is its reported effectiveness in treatment of numerous nervous system diseases. (iptq.com)
  • There is also no consensus on whether all cases of cycticercosis of the central nervous system benefit from cestocidal treatment with its associated sophisticated diagnostic assessment, or whether simple symptomatic treatment with antiepileptic drugs alone can provide them sustained comfort and quality of life. (who.int)
  • Multiple sclerosis ( MS ) is a disease that causes demyelination (disruption of the myelin that insulates and protects nerve cells) of spinal nerve and brain cells. (medicinenet.com)
  • Multiple sclerosis is a disease that causes demyelination of the brain and spinal cord nerve cells. (medicinenet.com)
  • The brain, spinal cord, and nerves make up the nervous system. (medlineplus.gov)
  • The central nervous system (CNS) is a complex, sophisticated network of neurons that includes our brain and spinal cord. (roche.com)
  • After numerous blood tests they found an antibody attacking my nervous system and brain they said. (mayoclinic.org)
  • The brain is the anterior part of the central nervous system, which is based on a nerve cell. (abchealthonline.com)
  • Following this, the areas of their brain that correlate with certain brain diseases were damaged. (medicalnewstoday.com)
  • Syphilitic infection of the nervous system results in the most chronic, insidious meningeal inflammatory process known. (medscape.com)
  • When people eat undercooked pork containing viable cysticerci, they develop an intestinal tapeworm infection, but not cysticercosis of the central nervous system. (who.int)
  • In non-endemic industrialized countries imported cases have been found in, for example, carriers of intestinal-stage T. solium infection, who, through food-handling and other modes of contact, can be sources of locally-acquired cases, and persons with latent cysticercosis of the central nervous system. (who.int)
  • This is particularly enticing for neuronal conditions, as the nervous system is renowned for its intransigence to therapeutic targeting. (frontiersin.org)
  • PROPAGAGEING: The continuum between healthy ageing and idiopathic Parkinson Disease with a propagation perspective of inflammation and damage: the search for new diagnostic, prognostic and therapeutic targets" Horizon 2020. (unibo.it)
  • In 2023, AFM-Telethon is supporting 39 trials underway or in preparation in 30 rare diseases . (afm-telethon.fr)
  • Diagnostic criteria based on objective clinical, imaging, immunological and epidemiological data have been proposed for different levels of the health care system, but are not generally used in areas endemic for the disease. (who.int)
  • The TGen team led the clinical development of one of the current standard-of-care regimens for this disease -- nab-paclitaxel plus gemcitabine. (medindia.net)
  • However, greater attention regarding the involvement of thrombin in normal and pathological processes in the central nervous system is warranted. (tau.ac.il)
  • MS is an autoimmune condition that affects the central nervous system . (medicalnewstoday.com)
  • On top of that, this disease affects their brains and makes them fearless. (listverse.com)
  • PeV-A3 is most often associated with severe disease. (cdc.gov)
  • Congenital Heart Disease and Risk of Central Nervous System Infections: A Nationwide Cohort Study. (bvsalud.org)
  • Congenital heart disease (CHD) is associated with risk factors of central nervous system (CNS) infections including infective endocarditis , cardiac shunt physiology , and immune deficiencies. (bvsalud.org)
  • Atopic dermatitis (AD) and inflammatory bowel disease (IBD) can lead to alterations in the microbiome, and disruptions in the skin and gut barrier. (medindia.net)
  • and other diseases, including those involving inflammation and the central nervous system. (medindia.net)
  • Current treatments for MS can reduce the severity of the disease, and slow its progression. (medicalnewstoday.com)
  • Neurosyphilis, quite directly, is defined as a CSF WBC count of 20 cells/µL or greater or a reactive CSF Venereal Disease Research Laboratory (VDRL) test result. (medscape.com)
  • Tuberculosis (TB) of the central nervous system (CNS) is classically described as meningitis. (cdc.gov)
  • To address the challenge of diagnosing these highly complex diseases, new diagnostic strategies were required. (roche.com)
  • In contrast, estimates of the burden of occupational injury and illness are more difficult to accomplish because they rely on far more primary and secondary sources of data on more than 18 diseases and a substantial number of injury types. (cdc.gov)
  • Persons not treated for persistent CSF abnormalities are at risk of developing clinically apparent disease and are hereafter referred to as having contracted neurosyphilis. (medscape.com)
  • Few other diseases have inflicted such a burden of suffering on humankind as the one that became known as the great imitator. (medscape.com)
  • However, the national investment in addressing occupational illness and injuries is far less than for many other diseases with lower economic burden even though occupational illnesses and injuries are eminently preventable. (cdc.gov)
  • The complexities of CNS disease require continued research. (roche.com)
  • Despite expansion of the geographic distribution of Baylisascaris procyonis in the last 14 years ( 2 ) and probable increasing human exposure, baylisascariasis is likely an underreported disease: only 22 documented cases were reported in the United States during 1973-2010 ( 3 , 4 ). (cdc.gov)
  • Syphilis is a sexually transmitted disease caused by Treponema pallidum, with human beings as the only host. (medscape.com)
  • Such a route of transmission is strongly supported by the concentration of cases of cysticercosis of the central nervous system in communities with human carriers of Taenia , which clustering also supports the argument that carriers of Taenia are potent sources of contagion. (who.int)
  • Human cysticercosis is a disease associated with poverty in areas where people eat pork and traditional pig husbandry is practised. (who.int)
  • Human African trypanosomiasis, or sleeping sickness, is a widespread tropical disease that can be fatal if not treated. (who.int)
  • This reinforced the social stigmata attached to the disease by associating it with shameful and immoral behavior. (medscape.com)
  • Central nervous system tuberculosis (TB) was identified in 20 cases of unexplained encephalitis referred to the California Encephalitis Project. (cdc.gov)
  • In Ecuador, about 10% of all cases of epilepsy, and 25% of those attributable to a particular identifiable event, were due to cysticercosis of the central nervous system. (who.int)
  • Tsetse flies are found just in sub-Saharan Africa though only certain species transmit the disease. (who.int)