Nerve Endings
Branch-like terminations of NERVE FIBERS, sensory or motor NEURONS. Endings of sensory neurons are the beginnings of afferent pathway to the CENTRAL NERVOUS SYSTEM. Endings of motor neurons are the terminals of axons at the muscle cells. Nerve endings which release neurotransmitters are called PRESYNAPTIC TERMINALS.
Sciatic Nerve
A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.
Nerve Fibers
Peripheral Nerves
The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
Optic Nerve
The 2nd cranial nerve which conveys visual information from the RETINA to the brain. The nerve carries the axons of the RETINAL GANGLION CELLS which sort at the OPTIC CHIASM and continue via the OPTIC TRACTS to the brain. The largest projection is to the lateral geniculate nuclei; other targets include the SUPERIOR COLLICULI and the SUPRACHIASMATIC NUCLEI. Though known as the second cranial nerve, it is considered part of the CENTRAL NERVOUS SYSTEM.
Synaptosomes
Pituitary Gland, Posterior
Neural tissue of the pituitary gland, also known as the neurohypophysis. It consists of the distal AXONS of neurons that produce VASOPRESSIN and OXYTOCIN in the SUPRAOPTIC NUCLEUS and the PARAVENTRICULAR NUCLEUS. These axons travel down through the MEDIAN EMINENCE, the hypothalamic infundibulum of the PITUITARY STALK, to the posterior lobe of the pituitary gland.
Mechanoreceptors
Neurosecretion
Trigeminal Nerve
The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.
Sensory Receptor Cells
Nerve Block
Sympathetic Nervous System
The thoracolumbar division of the autonomic nervous system. Sympathetic preganglionic fibers originate in neurons of the intermediolateral column of the spinal cord and project to the paravertebral and prevertebral ganglia, which in turn project to target organs. The sympathetic nervous system mediates the body's response to stressful situations, i.e., the fight or flight reactions. It often acts reciprocally to the parasympathetic system.
Sural Nerve
Median Nerve
Facial Nerve
The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and SALIVARY GLANDS, and convey afferent information for TASTE from the anterior two-thirds of the TONGUE and for TOUCH from the EXTERNAL EAR.
Tibial Nerve
Ulnar Nerve
Phrenic Nerve
Cats
The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)
Acetylcholine
Neural Conduction
Merkel Cells
Modified epidermal cells located in the stratum basale. They are found mostly in areas where sensory perception is acute, such as the fingertips. Merkel cells are closely associated with an expanded terminal bulb of an afferent myelinated nerve fiber. Do not confuse with Merkel's corpuscle which is a combination of a neuron and an epidermal cell.
Muscle Spindles
Skeletal muscle structures that function as the MECHANORECEPTORS responsible for the stretch or myotactic reflex (REFLEX, STRETCH). They are composed of a bundle of encapsulated SKELETAL MUSCLE FIBERS, i.e., the intrafusal fibers (nuclear bag 1 fibers, nuclear bag 2 fibers, and nuclear chain fibers) innervated by SENSORY NEURONS.
Femoral Nerve
Spinal Nerves
Motor Endplate
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
Microscopy, Electron
Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen.
Nerve Growth Factors
Nerve Growth Factor
Spinal Nerve Roots
Paired bundles of NERVE FIBERS entering and leaving the SPINAL CORD at each segment. The dorsal and ventral nerve roots join to form the mixed segmental spinal nerves. The dorsal roots are generally afferent, formed by the central projections of the spinal (dorsal root) ganglia sensory cells, and the ventral roots are efferent, comprising the axons of spinal motor and PREGANGLIONIC AUTONOMIC FIBERS.
Pacinian Corpuscles
Rapidly adapting mechanoreceptors found in subcutaneous tissue beneath both hairy and glabrous skin. Pacinian corpuscles contain an afferent nerve fiber surrounded by a capsule with multiple concentric layers. They have large receptive fields and are most sensitive to high-frequency stimuli, such as vibration.
Laryngeal Mucosa
Radial Nerve
A major nerve of the upper extremity. In humans the fibers of the radial nerve originate in the lower cervical and upper thoracic spinal cord (usually C5 to T1), travel via the posterior cord of the brachial plexus, and supply motor innervation to extensor muscles of the arm and cutaneous sensory fibers to extensor regions of the arm and hand.
Substance P
Cranial Nerves
Guinea Pigs
Afferent Pathways
Nerve Tissue
Neurotransmitter Agents
Mandibular Nerve
Calcitonin Gene-Related Peptide
Calcitonin gene-related peptide. A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Nerve Compression Syndromes
Thermoreceptors
Moles
Synaptic Vesicles
Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.
Rana pipiens
Ophthalmic Nerve
Ubiquitin Thiolesterase
Nociceptors
Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Cochlear Nerve
Action Potentials
Nerve Degeneration
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
Synaptic Transmission
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
Presynaptic Terminals
The distal terminations of axons which are specialized for the release of neurotransmitters. Also included are varicosities along the course of axons which have similar specializations and also release transmitters. Presynaptic terminals in both the central and peripheral nervous systems are included.
Oculomotor Muscles
Guanethidine
An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Rats, Sprague-Dawley
Abducens Nerve
Calcium
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Nerve Fibers, Myelinated
A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.
Oculomotor Nerve
The 3d cranial nerve. The oculomotor nerve sends motor fibers to the levator muscles of the eyelid and to the superior rectus, inferior rectus, and inferior oblique muscles of the eye. It also sends parasympathetic efferents (via the ciliary ganglion) to the muscles controlling pupillary constriction and accommodation. The motor fibers originate in the oculomotor nuclei of the midbrain.
Synapsins
A family of synaptic vesicle-associated proteins involved in the short-term regulation of NEUROTRANSMITTER release. Synapsin I, the predominant member of this family, links SYNAPTIC VESICLES to ACTIN FILAMENTS in the presynaptic nerve terminal. These interactions are modulated by the reversible PHOSPHORYLATION of synapsin I through various signal transduction pathways. The protein is also a substrate for cAMP- and CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES. It is believed that these functional properties are also shared by synapsin II.
Synaptophysin
Atropine
Splanchnic Nerves
The major nerves supplying sympathetic innervation to the abdomen. The greater, lesser, and lowest (or smallest) splanchnic nerves are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses. The lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia.
Glossopharyngeal Nerve
The 9th cranial nerve. The glossopharyngeal nerve is a mixed motor and sensory nerve; it conveys somatic and autonomic efferents as well as general, special, and visceral afferents. Among the connections are motor fibers to the stylopharyngeus muscle, parasympathetic fibers to the parotid glands, general and taste afferents from the posterior third of the tongue, the nasopharynx, and the palate, and afferents from baroreceptors and CHEMORECEPTOR CELLS of the carotid sinus.
Ganglia, Autonomic
Clusters of neurons and their processes in the autonomic nervous system. In the autonomic ganglia, the preganglionic fibers from the central nervous system synapse onto the neurons whose axons are the postganglionic fibers innervating target organs. The ganglia also contain intrinsic neurons and supporting cells and preganglionic fibers passing through to other ganglia.
rab3A GTP-Binding Protein
Receptors, Histamine H3
A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H3 receptors were first recognized as inhibitory autoreceptors on histamine-containing nerve terminals and have since been shown to regulate the release of several neurotransmitters in the central and peripheral nervous systems. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
Muscle Contraction
Electrophysiology
Parasympathetic Nervous System
The craniosacral division of the autonomic nervous system. The cell bodies of the parasympathetic preganglionic fibers are in brain stem nuclei and in the sacral spinal cord. They synapse in cranial autonomic ganglia or in terminal ganglia near target organs. The parasympathetic nervous system generally acts to conserve resources and restore homeostasis, often with effects reciprocal to the sympathetic nervous system.
Nodose Ganglion
Rats, Wistar
Nerve Fibers, Unmyelinated
A class of nerve fibers as defined by their nerve sheath arrangement. The AXONS of the unmyelinated nerve fibers are small in diameter and usually several are surrounded by a single MYELIN SHEATH. They conduct low-velocity impulses, and represent the majority of peripheral sensory and autonomic fibers, but are also found in the BRAIN and SPINAL CORD.
Ganglia, Sensory
Neurofilament Proteins
Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in Alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of Alzheimer's patients. (Can J Neurol Sci 1990 Aug;17(3):302)
Optic Nerve Injuries
Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.
2-Chloroadenosine
Optic Nerve Diseases
Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
Chemoreceptor Cells
Ganglia, Spinal
Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch bifurcates sending a peripheral process to carry sensory information from the periphery and a central branch which relays that information to the spinal cord or brain.
Immunohistochemistry
Thoracic Nerves
Vagus Nerve
The 10th cranial nerve. The vagus is a mixed nerve which contains somatic afferents (from skin in back of the ear and the external auditory meatus), visceral afferents (from the pharynx, larynx, thorax, and abdomen), parasympathetic efferents (to the thorax and abdomen), and efferents to striated muscle (of the larynx and pharynx).
Sympathectomy
Reflex
Fasciculation
Involuntary contraction of the muscle fibers innervated by a motor unit. Fasciculations can often by visualized and take the form of a muscle twitch or dimpling under the skin, but usually do not generate sufficient force to move a limb. They may represent a benign condition or occur as a manifestation of MOTOR NEURON DISEASE or PERIPHERAL NERVOUS SYSTEM DISEASES. (Adams et al., Principles of Neurology, 6th ed, p1294)
Accessory Nerve
The 11th cranial nerve which originates from NEURONS in the MEDULLA and in the CERVICAL SPINAL CORD. It has a cranial root, which joins the VAGUS NERVE (10th cranial) and sends motor fibers to the muscles of the LARYNX, and a spinal root, which sends motor fibers to the TRAPEZIUS and the sternocleidomastoid muscles.
Skin
Carotid Body
A small cluster of chemoreceptive and supporting cells located near the bifurcation of the internal carotid artery. The carotid body, which is richly supplied with fenestrated capillaries, senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control.
Tachyphylaxis
Tetrodotoxin
Facial Nerve Injuries
Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., "crocodile tears") and other syndromes.
Synapses
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Acetylcholinesterase
Histamine Agonists
Cranial Nerve Neoplasms
Facial Nerve Diseases
Diseases of the facial nerve or nuclei. Pontine disorders may affect the facial nuclei or nerve fascicle. The nerve may be involved intracranially, along its course through the petrous portion of the temporal bone, or along its extracranial course. Clinical manifestations include facial muscle weakness, loss of taste from the anterior tongue, hyperacusis, and decreased lacrimation.
Motor Neurons, Gamma
Motor neurons which activate the contractile regions of intrafusal SKELETAL MUSCLE FIBERS, thus adjusting the sensitivity of the MUSCLE SPINDLES to stretch. Gamma motor neurons may be "static" or "dynamic" according to which aspect of responsiveness (or which fiber types) they regulate. The alpha and gamma motor neurons are often activated together (alpha gamma coactivation) which allows the spindles to contribute to the control of movement trajectories despite changes in muscle length.
Nictitating Membrane
Synaptic Membranes
Recurrent Laryngeal Nerve
Branches of the vagus (tenth cranial) nerve. The recurrent laryngeal nerves originate more caudally than the superior laryngeal nerves and follow different paths on the right and left sides. They carry efferents to all muscles of the larynx except the cricothyroid and carry sensory and autonomic fibers to the laryngeal, pharyngeal, tracheal, and cardiac regions.
Rats, Inbred Strains
Lingual Nerve
Dogs
Olfactory Nerve
Membrane Potentials
The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).
Axonal Transport
Adenosine
Desipramine
A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors.
Diaphragm
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
Hypoglossal Nerve
Electric Organ
In about 250 species of electric fishes, modified muscle fibers forming disklike multinucleate plates arranged in stacks like batteries in series and embedded in a gelatinous matrix. A large torpedo ray may have half a million plates. Muscles in different parts of the body may be modified, i.e., the trunk and tail in the electric eel, the hyobranchial apparatus in the electric ray, and extrinsic eye muscles in the stargazers. Powerful electric organs emit pulses in brief bursts several times a second. They serve to stun prey and ward off predators. A large torpedo ray can produce of shock of more than 200 volts, capable of stunning a human. (Storer et al., General Zoology, 6th ed, p672)
Phenoxybenzamine
Anura
Serotonin
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Brain
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Calbindin 1
Receptors, Presynaptic
omega-Conotoxins
Evoked Potentials
Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported.
Exocytosis
Receptors, Nerve Growth Factor
Histocytochemistry
Trachea
Phentolamine
Tachykinins
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
Nose
Abducens Nerve Diseases
Diseases of the sixth cranial (abducens) nerve or its nucleus in the pons. The nerve may be injured along its course in the pons, intracranially as it travels along the base of the brain, in the cavernous sinus, or at the level of superior orbital fissure or orbit. Dysfunction of the nerve causes lateral rectus muscle weakness, resulting in horizontal diplopia that is maximal when the affected eye is abducted and ESOTROPIA. Common conditions associated with nerve injury include INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; ISCHEMIA; and INFRATENTORIAL NEOPLASMS.
Vestibular Nerve
The vestibular part of the 8th cranial nerve (VESTIBULOCOCHLEAR NERVE). The vestibular nerve fibers arise from neurons of Scarpa's ganglion and project peripherally to vestibular hair cells and centrally to the VESTIBULAR NUCLEI of the BRAIN STEM. These fibers mediate the sense of balance and head position.
Aminobutyrates
Dopamine
One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
Neurons
Neuropeptides
Potassium
An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
Maxillary Nerve
Joint Capsule
Hexamethonium Compounds
Pressoreceptors
Oculomotor Nerve Diseases
Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)
Calcium Channel Blockers
Nerve Sheath Neoplasms
Botulinum Toxins
Toxic proteins produced from the species CLOSTRIDIUM BOTULINUM. The toxins are synthesized as a single peptide chain which is processed into a mature protein consisting of a heavy chain and light chain joined via a disulfide bond. The botulinum toxin light chain is a zinc-dependent protease which is released from the heavy chain upon ENDOCYTOSIS into PRESYNAPTIC NERVE ENDINGS. Once inside the cell the botulinum toxin light chain cleaves specific SNARE proteins which are essential for secretion of ACETYLCHOLINE by SYNAPTIC VESICLES. This inhibition of acetylcholine release results in muscular PARALYSIS.
Physostigmine
TRPV Cation Channels
Peripheral Nervous System Diseases
Muscle, Smooth
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Dose-Response Relationship, Drug
Receptors, Purinergic
Periodontal Ligament
Tendons
Spinal Cord
Hemicholinium 3
A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
Pineal Gland
Ganglionic Blockers
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Schwann Cells
Autonomic Nervous System
The ENTERIC NERVOUS SYSTEM; PARASYMPATHETIC NERVOUS SYSTEM; and SYMPATHETIC NERVOUS SYSTEM taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the CENTRAL NERVOUS SYSTEM, especially the HYPOTHALAMUS and the SOLITARY NUCLEUS, which receive information relayed from VISCERAL AFFERENTS.
Sciatic Neuropathy
Disease or damage involving the SCIATIC NERVE, which divides into the PERONEAL NERVE and TIBIAL NERVE (see also PERONEAL NEUROPATHIES and TIBIAL NEUROPATHY). Clinical manifestations may include SCIATICA or pain localized to the hip, PARESIS or PARALYSIS of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. The sciatic nerve may be affected by trauma; ISCHEMIA; COLLAGEN DISEASES; and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1363)
Hindlimb
Microscopy, Immunoelectron
Sodium
Cranial Nerve Injuries
Receptors, Adrenergic, alpha
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
S100 Calcium Binding Protein G
A calbindin protein found in many mammalian tissues, including the UTERUS, PLACENTA, BONE, PITUITARY GLAND, and KIDNEYS. In intestinal ENTEROCYTES it mediates intracellular calcium transport from apical to basolateral membranes via calcium binding at two EF-HAND MOTIFS. Expression is regulated in some tissues by VITAMIN D.
Epinephrine
The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS.
Receptors, Adrenergic
Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.
Cerebral Cortex
Neurotoxins
Chorda Tympani Nerve
Rabbits
Stimulation, Chemical
The increase in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.
Pain
Calcium Channels
Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
Further evidence that prostaglandins inhibit the release of noradrenaline from adrenergic nerve terminals by restriction of availability of calcium. (1/1058)
1 Guinea-pig vasa deferentia were continuously superfused after labelling the transmitter stores with [3H](-)-noradrenaline. Release of [3H]-(-)-noradrenaline was induced by transmural nerve stimulation. 2 Prostglandin E2 (14 nM) drastically reduced the release of [3H]-(-)-noradrenaline, while tetraethylammonium (2 mM), rubidium (6 mM), phenoxybenzamine (3 muM) each in the presence or absence of Uptake 1 or 2 blockade, and prolonged pulse duration (from 0.5 to 2.0 ms) all significantly increased the release of [3H]-(-)-noradrenaline per nerve impulse. 3 The inhibitory effect of prostaglandin E2 on evoked release of [3H]-(-)-noradrenaline was significantly reduced by tetraethylammonium, rubidium and prolonged pulse duration, whilst it was actually enhanced by phenoxybenzamine. This indicates that increased release of noradrenaline per nerve impulse does not per se counteract the inhibitory effect of prostaglandin E2. 4 It is concluded that tetraethylammonium, rubidium and prolonged pulse duration counteracted the inhibitory effect of prostaglandin E2 on T3H]-(-)-noradrenaline release by promoting calcium influx during the nerve action potential. The results are consistent with, and add more weight to the view that prostaglandins inhibit the release of noradrenaline by restriction of calcium availability. (+info)Facilitatory beta2-adrenoceptors on cholinergic and adrenergic nerve endings of the guinea pig trachea. (2/1058)
Using electrical field stimulation of epithelium-denuded intact guinea pig tracheal tube preparations, we studied the presence and role of prejunctional beta2-adrenoceptors by measuring evoked endogenous acetylcholine (ACh) and norepinephrine (NE) release directly. Analysis of ACh and NE was through two HPLC systems with electrochemical detection. Electrical field stimulation (150 mA, 0.8 ms, 16 Hz, 5 min, biphasic pulses) released 29.1 +/- 2.5 pmol ACh/g tissue and 70.2 +/- 6.2 pmol NE/g tissue. Preincubation for 15 min with the selective beta2-adrenoceptor agonist fenoterol (1 microM) increased both ACh and NE overflow to 178 +/- 28 (P < 0.01) and 165 +/- 12% (P < 0.01), respectively, of control values, increases that were abolished completely by the selective beta2-adrenoceptor antagonist ICI-118551 (1 microM). Further experiments with increasing fenoterol concentrations (0.1-100 microM) and different preincubation periods (1, 5, and 15 min) showed a strong and concentration-dependent facilitation of NE release, with maximum response levels decreasing (from nearly 5-fold to only 2.5-fold of control value) with increasing agonist contact time. In contrast, sensitivity of facilitatory beta2-adrenoceptors on cholinergic nerves to fenoterol gradually increased when the incubation period was prolonged; in addition, a bell-shaped concentration-response relationship was found at 15 min of preincubation. Fenoterol concentration-response relationships (15-min agonist preincubation) in the presence of atropine and yohimbine (1 microM each) were similar in the case of NE release, but in the case of ACh release, the bell shape was lost. The results indicate a differential capacity and response time profile of facilitatory prejunctional beta2-adrenoceptors on adrenergic and cholinergic nerve terminals in the guinea pig trachea and suggest that the receptors on adrenergic nerves are more susceptible to desensitization. (+info)Stimulus-secretion coupling in neurohypophysial nerve endings: a role for intravesicular sodium? (3/1058)
It is generally accepted that Ca is essentially involved in regulated secretion, but the role of this cation, as well as others such as Na, is not well understood. An illustrative example occurs in neurohypophysial secretion, where an experimentally induced increase in the cytosolic concentration of Na+ can induce continuous neuropeptide release. In contrast, an increase in cytosolic Ca2+ will have only a transient stimulatory effect. The secretion-promoting targets for Ca2+ are not known; they may be cytosolic, as is usually assumed, but they may also be intravesicular, especially in view of evidence that Ca-rich secretory vesicles are preferentially secreted. In the present work, we have investigated the movements of these cations into and out of secretory vesicles during stimulus-secretion coupling. Isolated rat neurohypophysial nerve endings were stimulated by potassium (55 mM) depolarization, and at 6 min (peak secretion) and 20 min after the onset of stimulation, the elemental content of individual secretory vesicles was measured by quantitative x-ray microanalysis. A depolarization-induced transient increase in intravesicular Na+ concentration was found to coincide with the onset of secretion. Moreover, only a predicted small fraction of peripheral vesicles-presumably the docked ones-were Na+-loaded. The low sulfur concentration of Na+-rich vesicles most likely resulted from vesicle swelling. The results suggest that high intravesicular Na+ concentrations in docked vesicles, occurring by Na+/Ca2+ exchange or by transient fusion pore opening, is a proximal event in exocytosis. (+info)Quantal secretion and nerve-terminal cable properties at neuromuscular junctions in an amphibian (Bufo marinus). (4/1058)
The effect of a conditioning depolarizing current pulse (80-200 micros) on quantal secretion evoked by a similar test pulse at another site was examined in visualized motor-nerve terminal branches of amphibian endplates (Bufo marinus). Tetrodotoxin (200 nM) and cadmium (50 microM) were used to block voltage-dependent sodium and calcium conductances. Quantal release at the test electrode was depressed at different distances (28-135 microm) from the conditioning electrode when the conditioning and test pulses were delivered simultaneously. This depression decreased when the interval between conditioning and test current pulses was increased, until, at an interval of approximately 0.25 ms, it was negligible. At no time during several thousand test-conditioning pairs, for electrodes at different distances apart (28-135 microm) on the same or contiguous terminal branches, did the electrotonic effects of quantal release at one electrode produce quantal release at the other. Analytic and numerical solutions were obtained for the distribution of transmembrane potential at different sites along terminal branches of different lengths for current injection at a point on a terminal branch wrapped in Schwann cell, in the absence of active membrane conductances. Solutions were also obtained for the combined effects of two sites of current injection separated by different time delays. This cable model shows that depolarizing current injections of a few hundred microseconds duration produce hyperpolarizations at approximately 30 microm beyond the site of current injection, with these becoming larger and occurring at shorter distances the shorter the terminal branch. Thus the effect of a conditioning depolarizing pulse at one site on a subsequent test pulse at another more than approximately 30 microm away is to substantially decrease the absolute depolarization produced by the latter, provided the interval between the pulses is less than a few hundred microseconds. It is concluded that the passive cable properties of motor nerve terminal branches are sufficient to explain the effects on quantal secretion by a test electrode depolarization of current injections from a spatially removed conditioning electrode. (+info)Synaptic vesicle dynamics in rat fast and slow motor nerve terminals. (5/1058)
We have investigated whether rat motor nerve terminals with different in vivo activity patterns also have different vesicle trafficking characteristics. To do this, we monitored, using combined optical and electrical techniques, the rate of exocytosis (during different frequencies and patterns of activity), the releasable pool size, and the recycle time of synaptic vesicles in terminals on soleus (slow-twitch) and extensor digitorum longus [(EDL); fast-twitch] muscle fibers. EDL terminals had a higher initial quantal content (QC) than soleus, but during tonic or phasic stimulation at 20-80 Hz, EDL QC ran down to a greater extent than soleus QC. By recording loss of fluorescence from exocytosing vesicles labeled with the dye FM1-43, EDL terminals were found to destain faster than those in soleus. Simultaneous intracellular recording of end plate potentials, to count the number of vesicles released, permitted estimation of the total vesicle pool (VP) size and the recycle time by combining the optical and electrophysiological data. Soleus vesicle pool was larger than EDL, but recycle time was not significantly different. These terminals, therefore, are adapted to their in vivo activity patterns by alterations in QC and VP size but not recycle time. (+info)Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes. (6/1058)
Cholinergic deficits are one of the most consistent neuropathological landmarks in Alzheimer's disease (AD). We have examined transgenic mouse models (PS1M146L, APPK670N,M671L) and a doubly transgenic line (APPK670N,M671L + PS1M146L) that overexpress mutated AD-related genes [presenilin-1 (PS1) and the amyloid precursor protein (APP)] to investigate the effect of AD-related gene overexpression and/or amyloidosis on cholinergic parameters. The size of the basal forebrain cholinergic neurons and the pattern of cholinergic synapses in the hippocampus and cerebral cortex were revealed by immunohistochemical staining for choline acetyltransferase and the vesicular acetylcholine transporter, respectively. At the time point studied (8 months), no apparent changes in either the size or density of cholinergic synapses were found in the PS1M146L mutant relative to the nontransgenic controls. However, the APPK670N,M671L mutant showed a significant elevation in the density of cholinergic synapses in the frontal and parietal cortices. Most importantly, the double mutant (APPK670N,M671L + PS1M146L), which had extensive amyloidosis, demonstrated a prominent diminution in the density of cholinergic synapses in the frontal cortex and a reduction in the size of these synapses in the frontal cortex and hippocampus. Nonetheless, no significant changes in the size of basal forebrain cholinergic neurons were observed in these three mutants. This study shows a novel role of APP and a synergistic effect of APP and PS1 that correlates with amyloid load on the reorganization of the cholinergic network in the cerebral cortex and hippocampus at the time point studied. (+info)Isolation of pure cholinergic nerve endings from the electric organ of Torpedo marmorata. (7/1058)
A rapid method for the preparation of highly purified cholinergic nerve endings from the electric organ of Torpedo is described. The endings retain their cytoplasmic components, as shown by biochemical and morphological observations. The homogeneity of these synaptosomes make them a useful tool for further studies. (+info)Specific alteration of spontaneous GABAergic inhibition in cerebellar purkinje cells in mice lacking the potassium channel Kv1. 1. (8/1058)
In the cerebellum, the basket cell innervation on Purkinje cells provides a major GABAergic inhibitory control of the single efferent output from the cerebellum. The Shaker-type K channel Kv1.1 is localized at the axon arborization preceding the terminal of the basket cells and is therefore a potential candidate for regulating the GABAergic inhibition. In this study, we directly assess this role of Kv1.1 by electrophysiological analysis of Kv1.1 null mutant mice. Whole-cell patch-clamp recordings of spontaneous IPSCs (sIPSCs) were made from Purkinje cells in thin cerebellar slices from postnatal day (P)10-15 Kv1.1-null mutants using wild-type littermates as controls. The null mutation confers a very specific change in the sIPSC: the frequency increases about twofold, without accompanying changes in the mean and variance of its amplitude distribution. The frequency and amplitude of the miniature IPSCs (mIPSCs) are unaffected. Spontaneous firing rate of the basket cells is unaltered. Evoked IPSC does not show multiple activity in the mutants. Motor skills tests show that Kv1.1 null mice display a compromised ability to maintain balance on a thin stationary rod. We conclude that the Kv1.1 null mutation results in a persistent elevation of the tonic inhibitory tone on the cerebellum Purkinje cell efferent and that this is not fully compensated for by residual Shaker-type channels. We further suggest that the increase in inhibitory tone in the mutants might underlie the behavioral deficits. At the cellular level, we propose that Kv1.1 deletion enhances excitability of the basket cells by selectively enhancing the likelihood of action potential propagation past axonal branch points. (+info)
Calcium Dependence of Large Dense-Cored Vesicle Exocytosis Evoked by C by Kathrin L. Engisch and Martha C. Nowycky
Enlarged nerve endings on the penis Comentarios sobre titan gel
PET Scan in Patients With Neurocardiologic Disorders - Full Text View - ClinicalTrials.gov
Touching a nerve ending Synonyms, Touching a nerve ending Antonyms | Thesaurus.com
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NERVE ENDINGS
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§ 1.367(e)-2(b)(2)(i)
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Cody Vrosh: The Lack of Nerve Endings in the Brain
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Free nerve ending | Open Access articles | Open Access journals | Conference Proceedings | Editors | Authors | Reviewers |...
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Definition for free nerve ending
A slowly activating voltage-dependent K<sup>+</sup> current in rat pituitary nerve...
Histochemical and Biochemical Demonstration of Sialic Acid and Sulphate in Vesicles and Membranes Isolated from Nerve Endings...
Balance of Calcineurin Aα and CDK5 Activities Sets Release Probability at Nerve Terminals | Journal of Neuroscience
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Plus it
Fibromyalgia is Not All In Your Head, New Study Confirms - Chronic Pain Fighter
Jackson, Meyer
AID 65182 - Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) - PubChem
What part of the body has the most nerve endings?
Motor Nerve Endings in Muscle (Reptile) | Wards Science
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Nociceptors: the sensors of the pain pathway
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if the immune system targeted specific nerves cells why would the body not be able to feel the process of those nerves cells...
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Pain/Inflammation Management</span>
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Stephen Moses
"Marc Sloan Discography". Trees of Nerve Endings. Archived from the original on 2012-03-13. CS1 maint: discouraged parameter ( ...
Kristin Hersh
Nerve Endings: Selected Lyrics. Unbound, 2018. ISBN 978-1783525638. Erlewine, Stephen Thomas. "Kristin Hersh , Biography & ... Richards, John (February 13, 2007). "Nerves Exposed, Hersh Sings One for the Oddballs". NPR. Retrieved on October 24, 2016. ...
Presidency of Dwight D. Eisenhower
Blood pressure and temperature have gone down; nerve endings have healed over. The new tone could be described in a word: ... On July 27, 1953, the United States, North Korea, and China agreed to the Korean Armistice Agreement, ending the Korean War. ...
Artificial neural network
Adrian, Edward D. (1926). "The impulses produced by sensory nerve endings". The Journal of Physiology. 61 (1): 49-72. doi: ... Kleene, S.C. (1956). "Representation of Events in Nerve Nets and Finite Automata". Annals of Mathematics Studies (34). ...
Neuronal noise
Fatt, P.; Katz, B. (1952). "Spontaneous subthreshold activity at motor nerve endings". J Physiol. 117 (1): 109-128. doi:10.1113 ...
Oscar Werner Tiegs
... chemical transmission at dorsal root nerve endings. He was appointed to a Chair of Zoology at the University of Melbourne in ... Between 1922 and 1934 Oscar Tiegs was almost entirely concerned with the physiology of nerve and muscle, apparently influenced ...
Chemical synapse
doi:10.1016/b978-0-12-815480-9.00001-3. ISBN 978-0-12-815480-9. Rapport, Richard L. (2005). Nerve Endings: The Discovery of the ... I felt the need of some name to call the junction between nerve-cell and nerve-cell... I suggested using "syndesm"... He [ Sir ... The release of a neurotransmitter is triggered by the arrival of a nerve impulse (or action potential) and occurs through an ... Pereda AE, Rash JE, Nagy JI, Bennett MV (December 2004). "Dynamics of electrical transmission at club endings on the Mauthner ...
Northern leopard frog
"Spontaneous subthreshold activity at motor nerve endings". The Journal of Physiology. 117 (1): 109-28. doi:10.1113/jphysiol. ... The neuromuscular junction of the sciatic nerve fibers of the sartorius muscle of this frog has been the source of initial data ... Hille, B (1967). "The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion". The Journal of ...
Hip arthroscopy
However, this is not its only function, as it has been shown to contain nerve endings, which may cause pain if damaged. The ... The most common nerve to be injured is the lateral cutaneous nerve of the thigh. This nerve supplies feeling to the upper, ... Kim, Y.; Azuma, H. (1995). "The nerve endings of the acetabular labrum". Clinical Orthopaedics and Related Research (320): 176- ... and pudendal nerves. The pudendal nerves supply feeling to the reproductive organs. Persistent inflammation to the soft tissue ...
List of regions in the human brain
1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior Spinothalamic tract → Spinal ... Pontine cranial nerve nuclei *chief or pontine nucleus of the trigeminal nerve sensory nucleus (V) ... 1° (Group C nerve fiber → Spinoreticular tract → Reticular formation) → 2° (MD of Thalamus) → 3° (Cingulate cortex) ...
Glossary of diabetes
Epinephrine (adrenaline) a "neurotransmitter" at sympathetic nerve endings. And a hormone which has effects throughout the body ... Mononeuropathy A form of diabetic neuropathy affecting a single nerve. The eye is a common site for this form of nerve damage. ... Nerve conduction studies Tests to determine nerve function; can detect early neuropathy. Neurologist a physician specializing ... Electromyography EMG Test used to diagnose neuropathy and check for nerve damage. It uses electrodes to measure speed of nerve ...
Pathophysiology of asthma
Whenever these afferent nerve endings are stimulated (for example, by dust, cold air or fumes) impulses travel to the brain- ... The parasympathetic reflex loop consists of afferent nerve endings which originate under the inner lining of the bronchus. ... Acetylcholine is released from the efferent nerve endings. This acetylcholine results in the excessive formation of inositol 1, ...
Marthe Vogt
Vogt coauthored a paper with Dale and Wilhelm Feldberg: 'Release of Acetylcholine at Voluntary Motor Nerve Endings' in 1936. ... Dale, H.H.; Feldberg, W.; Vogt, M. (1936). "Release of Acetylcholine at Voluntary Motor Nerve Endings". Journal of Physiology. ... Dale, H.H.; Feldberg, W.; Vogt, M. (1936). "Release of Acetylcholine at Voluntary Motor Nerve Endings". Journal of Physiology. ... "Sir Henry Dale - Nobel Lecture: Some Recent Extensions of the Chemical Transmission of the Effects of Nerve Impulses". www. ...
Synaptic vesicle
With the advent of the electron microscope in the early 1950s, nerve endings were found to contain a large number of electron- ... Gray EG, Whittaker VP (1962). "The isolation of nerve endings from brain: an electron microscopic study of cell fragments ... Fatt, P.; Katz, B. (May 28, 1952). "Spontaneous subthreshold activity at motor nerve endings" (PDF). The Journal of Physiology ... Whittaker VP, Michaelson IA, Kirkland RJ (1964). "The separation of synaptic vesicles from nerve ending particles (' ...
Tactile corpuscle
... and some free nerve endings. Also, tactile corpuscles do not detect noxious stimuli; this is signaled exclusively by free nerve ... This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to light touch. In particular, they ... Tactile corpuscles are encapsulated myelinated nerve endings, surrounded by Schwann cells. The encapsulation consists of ... A single nerve fiber meanders between the lamellae and throughout the corpuscle. They are distributed on various areas of the ...
GPR55
Kress M, Kuner R (Jun 2009). "Mode of action of cannabinoids on nociceptive nerve endings". Experimental Brain Research. 196 (1 ...
Acorn worm
... numerous nerve endings throughout the skin. Acorn worms have a Y-shaped nuchal skeleton that starts their proboscis and collar ... A plexus of nerves lies underneath the skin, and is concentrated into both dorsal and ventral nerve cords. While the ventral ... This part of the dorsal nerve cord is often hollow, and may well be homologous with the brain of vertebrates. In acorn worms, ...
Glans penis
Merkel nerve endings and Meissner's corpuscles are not present." Yang & Bradley argue; "the distinct pattern of innervation of ... "the glans penis contains a predominance of free nerve endings, numerous genital end bulbs and rarely Pacinian and Ruffinian ... Yang, C. C.; W.E. Bradley (July 1998). "Neuroanatomy of the penile portion of the human dorsal nerve of the penis". British ...
Mechanoreceptor
... also known as Ruffini endings) detect tension deep in the skin and fascia. The Merkel nerve endings (also known as Merkel discs ... Mechanosensory free nerve endings detect touch, pressure, stretching, as well as the tickle and itch sensations. Itch ... They are all innervated by Aβ fibers, except the mechanorecepting free nerve endings, which are innervated by Aδ fibers. ... Each muscle spindle consists of sensory nerve endings wrapped around special muscle fibers called spindle fibers (also called ...
Juxtaoral organ of Chievitz
Close relations exist between epithelial cells and nerve endings. Histochemically, the parenchyma displays a characteristic ... embedded in connective tissue particularly rich in nerve fibers and sensory receptors. ...
Requiem (Killing Joke song)
Requiem was covered by the British post-punk band Eagulls in 2013 as the B-side to their "Nerve Endings" single, which received ... CS1 maint: discouraged parameter (link) "Eagulls - Nerve Endings (Vinyl)". Discogs. Retrieved 29 April 2018. CS1 maint: ...
Mental disorders diagnosed in childhood
This stretching causes the nerve endings to become dull. The child may not feel when they need to eliminate the feces or if the ...
Feature detection (nervous system)
Adrian ED, Zotterman Y (April 1926). "The impulses produced by sensory nerve-endings: Part II. The response of a Single End- ... Auditory nerve fibers take this slightly-processed sensory information to the cochlear nucleus where information either ... E.D. Adrian, Barlow's advisor, was the discoverer of the frequency code-the observation that sensory nerves convey signal ...
Fascia
... l tissues are frequently innervated by sensory nerve endings. These include myelinated as well as unmyelinated nerves. ... It serves as a storage medium of fat and water; as a passageway for lymph, nerve and blood vessels; and as a protective padding ... A fascial compartment is a section within the body that contains muscles and nerves and is surrounded by fascia. In the human ... In doing so, fasciae provide a supportive and movable wrapping for nerves and blood vessels as they pass through and between ...
Latrotoxin
α-LTX affects motor nerve endings and endocrine cells. No major enzymatic activities are associated. Instead, the toxin can ... The N-terminus of the α-LTX precursor molecule is preceded by short hydrophilic sequences ending with a cluster of basic amino ... This causes nerve terminal swelling. Further membrane potential disturbances occur due to permeability of small molecules, such ...
Terry Robb
"Opening Nerve Endings Concert Launches into Deep Space Fine." The Oregonian, Sep. 24, 1998. Anderson, Rick. "Terry Robb, ...
History of catecholamine research
G. Hertting; J. Axelrod (1961). "Fate of tritiated noradrenaline at the sympathetic nerve-endings". Nature. 192 (4798): 172-173 ... are liberated in the region of the sympathetic nerve endings when these are excited." The manuscript was received by Springer- ... In the meantime, Dale created a terminology that since has imprinted the thinking of neuroscientists: that nerve cells should ... For many responses to sympathetic nerve stimulation, the ATP co-stored with noradrenaline (see above) is a cotransmitter. It ...
All-or-none law
Adrian ED, Zotterman Y (April 1926). "The impulses produced by sensory nerve-endings: Part II. The response of a Single End- ... The above account deals with the response of a single nerve fibre. If a nerve trunk is stimulated, then as the exciting ... but a stronger stimulus excites all the nerve fibres. Increasing the stimulus further does increase the response of whole nerve ... The nerve fibre gives a maximum response or none at all. This is called the "all or none" principle. It is also Known as all or ...
Inland taipan
Beta-neurotoxins keep nerve endings from liberating the neurotransmitter acetylcholine. According to researcher Ronelle Welton ...
Leaf
The number of vein endings is very variable, as is whether second order veins end at the margin, or link back to other veins.[ ... 2 major basal nerves besides the midrib. Diagrams of venation patternsEdit. ... Some of the smallest veins (veinlets) may have their endings in the areoles, a process known as areolation.[26] These minor ... Ending abruptly with a flat end, that looks cut off.. SurfaceEdit. ...
Chiropractic
Efferent nerve-fibers carry impulses out from the center to their endings. Most of these go to muscles and are therefore called ... "Physiologists divide nerve-fibers, which form the nerves, into two classes, afferent and efferent. Impressions are made on the ... Thus, nerves carry impulses outward and sensations inward. The activity of these nerves, or rather their fibers, may become ... that vertebral subluxations caused pinched nerves in the intervertebral spaces in favor of subluxations causing altered nerve ...
Rudolf Wagner
His only original contributions to this work were on the sympathetic nerve, nerve-ganglia and nerve-endings, and he modestly ... nerve-endings, and the sympathetic nerves. ...
Muscle spindle
Efferent nerve fibers of gamma motoneurons also terminate in muscle spindles; they make synapses at either or both of the ends ... The sensory endings of a primary (group Ia) afferent and a secondary (group II) afferent coil around the non-contractile ... They convey length information to the central nervous system via afferent nerve fibers. This information can be processed by ... Primary type Ia sensory fibers (large diameter) spiral around all intrafusal muscle fibres, ending near the middle of each ...
Visual impairment
Injuries and cataracts affect the eye itself, while abnormalities such as optic nerve hypoplasia affect the nerve bundle that ... The work is explicitly incongruous, ending with the comment Did you ever see such a sight in your life, As three blind mice? ... Glaucoma causes visual field loss as well as severs the optic nerve.[35] Early diagnosis and treatment of glaucoma in patients ... to the occipital lobe of the brain that prevent the brain from correctly receiving or interpreting signals from the optic nerve ...
George Harrison
... as with the ending chord arpeggios on "A Hard Day's Night".[222] On this and other songs from the period, he used a ... as both men admitted that they often got on each other's nerves.[392] Rodriguez commented: "Even to the end of George's days, ... but the project was lost amid the litigation surrounding the former Beatles ending their business ties with Klein.[318] ...
Olfactory system
... and nerve fibers of the olfactory nerves.[1] Odor molecules can enter the peripheral pathway and reach the nasal cavity either ... Olfactory nerve fibers, which originate in the epithelium, pass through the cribriform plate, connecting the epithelium to the ... Olfactory nerves and fibers transmit information about odors from the peripheral olfactory system to the central olfactory ... causing an electrical response that spreads through the sensory neuron to the olfactory nerve fibers at the back of the nasal ...
Isotretinoin
In the U.S., around 2000 women became pregnant while taking the drug between 1982 and 2000, with most pregnancies ending in ... It is also used for treatment of neuroblastoma, a form of nerve cancer. ...
Lesbian
After MacLaine's character admits her love for Hepburn's, she hangs herself; this set a precedent for miserable endings in ... or speak to me there is not a nerve of fibre in my body that does not respond with a thrill of delight?"[76] ... effectively ending the movement, until 2004, when Grupo Safo - Grupo de Mujeres Lesbianas de Nicaragua was created, four years ... violent deaths in moral endings.[225] Samuel Taylor Coleridge's 1816 poem "Christabel" and the novella Carmilla (1872) by ...
List of atheists in science and technology
Rapport, Richard L. Nerve Endings: The Discovery of the Synapse. New York: W.W. Norton, 2005. Print. ... Emil du Bois-Reymond (1818-1896): German physician and physiologist, the discoverer of nerve action potential, and the father ... but lost his nerve at the last minute and walked out of the classroom, never to return. On his long walk home, he came up with ... received the 1986 Nobel Prize in Physiology or Medicine for their discovery of nerve growth factor (NGF).[233] ...
Talk:Mind-body dualism
The light from a star travels over intervening space and causes a disturbance in the optic nerve ending in an occurrence in the ... The brain has ganglia and nerve fibers, has neuroglia and vessels, has different colors (is colored this way or that) and so on ...
Bronchus
In about half of observed cases the cardiac bronchus presents as a short dead-ending bronchial stump, in the remainder the ... Nerve. Pulmonary branches of vagus nerve. Identifiers. Latin. Bronchus. MeSH. D001980. TA. A06.4.01.001. ...
PRNP
Kardos J, Kovács I, Hajós F, Kálmán M, Simonyi M (August 1989). "Nerve endings from rat brain tissue release copper upon ... The abnormal protein PrPSc accumulates in the brain and destroys nerve cells, which leads to the mental and behavioral features ...
March 17 - Simple English Wikipedia, the free encyclopedia
1968 - As a result of nerve gas testing in Skull Valley, Utah, US, over 6,000 sheep are found dead. ... 1776 - American Revolution: British forces evacuate Boston, Massachusetts, ending the Siege of Boston, after George Washington ... ending the first of the Scottish Wars of Independence. ...
When a Man Loves a Woman (film)
James Berardinelli stated that the "ending is too facile", and that the film took "longer than necessary to arrive at its ... resolution", adding that there are moments in it where the script would strike a raw nerve with certain people because of how ...
Commissural fiber
Merkel nerve ending. *Pacinian corpuscle. *Ruffini ending. *Muscle spindle. *Free nerve ending ... The nerve fibres which make up the white matter of the cerebral hemispheres are categorized on the basis of their course and ... The posterior commissure (also known as the epithalamic commissure) is a rounded nerve tract crossing the middle line on the ...
Phenethylamine
... nerve ending preparations isolated during homogenization and centrifugation of brain tissue) (24), research with reserpine and ...
Cyberware
... are attached to the severed nerve-endings of the patient. The patient is then taught how to operate the prosthetic, trying to ... Fromherz, Peter; "Neuroelectronic Interfacing: Semiconductor Chips with Ion Channels, Nerve Cells, and Brain"; Nanoelectronics ... an institute working on nerve cell/chip interconnection Wetware Technology. ...
Nipple stimulation
All breasts have the same number of nerve endings no matter how large they are. Accordingly, smaller breasts are more sensitive ...
Mental health
Yoga is a great example of an activity that calms your entire body and nerves. According to a study on well-being by Richards, ... and even ending lives because of the lack of action. There has been some effort to financially fund psychiatric support in ... Psychiatrist Walter Freeman believed that "an overload of emotions led to mental illness and "that cutting certain nerves in ...
Erb's palsy
... since the latissimus dorsi has roughly twice the number of nerve endings per square inch of other muscles. ... The most commonly involved nerves are the suprascapular nerve, musculocutaneous nerve, and the axillary nerve.[9][10] ... These form part of the brachial plexus, comprising the ventral rami of spinal nerves C5-C8 and thoracic nerve T1.[1][2][3] ... and it can result in nerve damage in the area from which the nerves were taken. Scarring can vary from faint scars along the ...
Tongue
Nerve. Sensory: Anterior 2/3: lingual nerve & chorda tympani Posterior 1/3: Glossopharyngeal nerve (IX) Motor Innervation: - CN ... The ue ending of the word seems to be a fourteenth-century attempt to show "proper pronunciation", but it is "neither ... The pharyngeal part is supplied by the glossopharyngeal nerve and the oral part is supplied by the lingual nerve (a branch of ... Taste and sensation: internal branch of the superior laryngeal nerve (itself a branch of the vagus nerve, CN X) ...
Evolution of mammals
... of cynodonts as channels that supplied blood vessels and nerves to vibrissae (whiskers) and suggested that this was evidence of ... beginning with animals that were very like their pelycosaur ancestors and ending with some that could easily be mistaken for ... A study of cranial openings for facial nerves connected whiskers in extant mammals indicate the Prozostrodontia, small ...
Chris Davis (baseball)
It was the Orioles' first game-ending pinch hit home run since Larry Sheets had one on August 24, 1988.[80] Davis struggled in ... "Davis battles blister, nerves in first Derby experience". Orioles.MLB.com. Archived from the original on July 17, 2014 ... an injury which was initially feared to be season-ending but wound up keeping him out only until September 6.[45][46] In an 11- ... After Markakis suffered a season-ending injury on September 8, Davis moved to right field for the remainder of the season and ...
Oviraptorosauria
... preserved tails ending in something like a pygostyle, a bony structure at the end of the tail that, in modern birds, is used to ... and the coracoid has the primitive coelurosaur shape with a proximal supracoracoidal nerve foramen and a moderate biceps ...
Sweat - Simple English Wikipedia, the free encyclopedia
The sweat gland is in the layer of skin called the dermis along with other "equipment," such as nerve endings, hair follicles ... Nerve cells from the sympathetic nervous system are connected to the sweat glands. There are two types of sweat glands: * ... So when you are nervous, anxious or afraid, there is an increase in sympathetic nerve activity in your body as well as an ... Sweat can be made in response to nerve stimulation, hot air temperature, and/or exercise. First, let's concentrate on how sweat ...
Fin
Unlike dolphins, these fish do not feel the bubbles, because they have bony fins without nerve endings. Nevertheless, they ...
Granule cell
Merkel nerve ending. *Pacinian corpuscle. *Ruffini ending. *Muscle spindle. *Free nerve ending ... The dendrites are short with claw-like endings that form glomeruli to receive mossy fibers, similar to cerebellar granule cells ... They are characterized by a very small soma and several short dendrites which terminate with claw-shaped endings. In the ...
Synapse
Merkel nerve ending. *Pacinian corpuscle. *Ruffini ending. *Muscle spindle. *Free nerve ending ... In the nervous system, a synapse[1] is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical ... Nerve cells have long been used as models for cellular polarization, and of particular interest are the mechanisms underlying ... The distinctive structure of nerve cells allows action potentials to travel directionally (from dendrites to cell body down the ...
Free nerve ending - Wikipedia
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber ending of a sensory neuron. Afferent ... Free nerve endings are unencapsulated and have no complex sensory structures. They are the most common type of nerve ending, ... Hada R (1990). "[Difference in responses of free nerve endings and Ruffini-type endings innervating the cat mandibular ... The majority of Aδ (A delta) fibers (group III) and C (group IV) fibers end as free nerve endings. ...
NERVE ENDINGS
I am new to this site and I was wondering if anyone could give me info on nerve endings. My husband had radical prostate ... As far as the nerve endings, someone on this forum mentioned that nerves regenerate at the rate of 1/2 inch per month, what ... I am new to this site and I was wondering if anyone could give me info on nerve endings. My husband had radical prostate ... I had non nerve sparing surgery 4 months ago. I didnt take any of the ED medications since they really dont help much in my ...
Receptor | nerve ending | Britannica
Free nerve endings definition | Drugs.com
Nerve endings firing away | Deccan Herald
hyper)sensitive nerve endings-paraesthesia - Neurology - MedHelp
Doc says its sensitive nerve endings. They tingle/throb constantly at the tip(nasal dorsal nerve?) The area below my lower... ... Doc says its sensitive nerve endings. They tingle/throb constantly at the tip(nasal dorsal nerve?) The area below my lower lip ... The concern would be for a meningioma irritating the nerve supplying the region you describe. If this is the case, the ...
Gangliosides, Neuraminidase and Sialyltransferase at the Nerve Endings | SpringerLink
Phys.org - nerve endings
Burning nerve ending in low back - Pain Management - MedHelp
Nerve burning/nerve freezing/nerve block procedure do help control pain. However, at times it leaves the person feeling numb in ... Nerve burning/nerve freezing/nerve block procedure do help control pain. However, at times it leaves the person feeling numb in ... Burning nerve ending in low back Pamelahobo Hi, to all of you out there.Boy this is surely wide spread.I want to tell all of ... Burning nerve ending in low back. Hi, to all of you out there.Boy this is surely wide spread.I want to tell all of how Sorry I ...
Merkel nerve ending
... Merkel nerve endings are mechanoreceptors found in the skin and mucosa of vertebrates that provide touch ... In mammals, Merkel nerve endings have a wide distribution. Merkel nerve endings are found in the basal layer of glabrous and ... Touch/mechanoreceptors: Pacinian corpuscles • Meissners corpuscles • Merkels discs • Ruffini endings • Free nerve endings • ... In mammals, electrical recordings from single afferent nerve fibres have shown that the responses Merkel nerve endings are ...
Spinal Cord Transsection? Hydrogel Tunnels Guide Growth of Nerve Endings Across Gaps
Injured nerves are known to sometime repair themselves, and in certain situations autografts can be performed to bridge gaps in ... Spinal Cord Transsection? Hydrogel Tunnels Guide Growth of Nerve Endings Across Gaps. December 18th, 2012 Medgadget Editors ... To make sure nutrients and oxygen would reach the regenerating nerve endings, the team created a spiral PEDOT design that ... The pictures of the spiral PEDOT design showed that the health of the nerve itself was nearly indistinguishable from a nerve ...
Effect of benactyzine and arecoline on the 45 Ca uptake by rat brain nerve endings | SpringerLink
Density and organization of free nerve endings in the corneal epithelium of the rabbit
Free nerve ending - wikidoc
A free nerve ending (FNE) is an unspecialized, afferent nerve ending, meaning it brings information from the bodys periphery ... Hada R (1990). "[Difference in responses of free nerve endings and Ruffini-type endings innervating the cat mandibular ... Ruffini endings • Free nerve endings - pain • Hair cells • Baroreceptor ... They are the most common type of nerve ending, and are most frequently found in the skin. They penetrate the epidermis and end ...
THE NERVES OF THE CAPILLARIES, WITH REMARKS ON NERVE-ENDINGS IN MUSCLE | JEM
THE NERVES OF THE CAPILLARIES, WITH REMARKS ON NERVE-ENDINGS IN MUSCLE. Chr. Sihler ... THE NERVES OF THE CAPILLARIES, WITH REMARKS ON NERVE-ENDINGS IN MUSCLE ... 7. The nerves supplying the capillaries connect also with sensory nerves and with nerves surrounding the larger blood-vessels, ... 1. The endings of the motor nerves in striped muscle remain on the outside of the sarcolemma. Aside from the surfaces of ...
Motor Nerve Endings in Muscle (Reptile) | Ward's Science
Why do our feet have so many nerve endings if we are constantly stepping on them? | Reference.com
The thousands of nerve endings in the human foot supply sensory feedback to the central nervous system, according to the ... What is a bundle of nerve fibers called?. A: A bundle of nerve fibers is referred to as a tract in the nervous system. Nerve ... The foot has more nerve endings per square inch than anywhere else in the body. Nerves constantly are sensing characteristics ... The thousands of nerve endings in the human foot supply sensory feedback to the central nervous system, according to the ...
Too Close To Touch (Epitaph) unleash emotive whirlwind with "Nerve Endings" video (exclusive) - Features - Alternative Press
"Nerve Endings" is culled from the bands album of the same name, which also exclusively premiered on AP earlier this year. ... Nerve Endings is about the internal conflict between an individuals heart and mind," says frontman Keaton Pierce. "Its about ... Too Close To Touch (Epitaph) unleash emotive whirlwind with "Nerve Endings" video (exclusive). October 29 2015, 3:50 PM EDT By ... Too Close To Touch are teaming up with AltPress for a premiere of their emotive "Nerve Endings" music video, which was directed ...
3B Spinal Cord and Nerve Endings Model | Ward's Science
Touching a nerve ending Synonyms, Touching a nerve ending Antonyms | Thesaurus.com
3B Scientific® Spinal Cord And Nerve Endings Model | Boreal Science
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings
The data clearly demonstrate that in mammalian neurosecretory nerve endings tetanus toxin acts at a step downstream from the ... Exocytosis was induced by challenging the permeabilized nerve endings with micromolar calcium concentrations. Tetanus toxin ... The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings. In: ... and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve ...
Optic Nerve and Ruffini Ending - MER.
Does a woman only have nerve endings near the front of her vagina?
Most of the nerve endings involved in sexual stimulation in a woman are in the clitoris. This is a small pea size organ that is ... I know this does not really matter but how far are the nerve endings of a womans vagina when it comes to sexual pleasure? I ... The vagina itself doesnt have many nerve endings, almost all the stimulation from sex comes from the various connections to ...
The Ultrastructure of Sensory Nerve Endings in the Penis of the Goat | Springer for Research & Development
Nerve Ending Tunica Albuginea Sensory Nerve Ending Free Nerve Ending Glans Penis These keywords were added by machine and not ... Three types of nerve endings were observed: 1. free nerve endings, 2. Ruffini corpuscles and 3. genital corpuscles. The free ... Halata Z., Johnson R.B., Kitchell R.L., Strasmann T. (1988) The Ultrastructure of Sensory Nerve Endings in the Penis of the ... The Ultrastructure of Sensory Nerve Endings in the Penis of the Goat. ...
ULTRASTRUCTURAL CYTOCHEMISTRY AND PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE IN ADRENERGIC NERVE ENDINGS. III. SELECTIVE INCREASE OF...
ULTRASTRUCTURAL CYTOCHEMISTRY AND PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE IN ADRENERGIC NERVE ENDINGS. III. SELECTIVE INCREASE OF ... ULTRASTRUCTURAL CYTOCHEMISTRY AND PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE IN ADRENERGIC NERVE ENDINGS. III. SELECTIVE INCREASE OF ... ULTRASTRUCTURAL CYTOCHEMISTRY AND PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE IN ADRENERGIC NERVE ENDINGS. III. SELECTIVE INCREASE OF ... ULTRASTRUCTURAL CYTOCHEMISTRY AND PHARMACOLOGY OF 5-HYDROXYTRYPTAMINE IN ADRENERGIC NERVE ENDINGS. III. SELECTIVE INCREASE OF ...
Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation | Journal of...
Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation. David M. ... Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation. David M. ... Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation. David M. ... MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), which damages dopamine nerve endings and cell bodies, causes extensive ...
Definition for free nerve ending
... microscopic sensory neurological endings inside skin that arent attached to any certain sensory receptor ... Definition for "free nerve ending"*microscopic sensory neurological endings inside skin that arent… ... How would you define free nerve ending?. All the definitions on AZdictionary were written by people just like you. Nows your ... microscopic sensory neurological endings inside skin that arent attached to any certain sensory receptor ...
Combined Recording of Mechanically Stimulated Afferent Output and Nerve Terminal Labelling in Mouse Hair Follicle Lanceolate...
... and novel technique for recording afferent discharge due to mechanical stimulation of lanceolate terminals of palisade endings ... such as Ia endings in muscle spindles15, and in the lanceolate endings here7, styryl dye labeling seems to reflect membrane ... To avoid nerve damage, however, ensure that the connective tissue is cushioning the nerve from compression on the surrounding ... For the recording electrode, ensure the internal diameter is a snug fit for the nerve, and the maximum length of nerve is drawn ...
RuffiniNeuronsAfferentDermisSpinalMotor nerveFibresPacinianFibersHair folliclesStimuliPresynapticMammalianMerkelTerminalPenisRegenerateFreeReceptorsCranial nervesSILVERSUN PICKUPSAxonSweat glandsMorphologyMechanoreceptorsMuscleBloody MaryDorsalBrainBlood-vesselsSlowlyDopamineTerminalsTibialStimulationPainPeripheral nervesCell bodiesUptakeSynaptosomes200,000GlabrousTissueNeuralReceptorTRPV1EpitheliumBundlesSensory feedbackMedialTrigeminalTypes
Ruffini4
- Some other types of mechanoreceptors, such as Pacinian corpuscles and Ruffini endings, are found primarily in subcutaneous tissue . (bionity.com)
- In this artist book the process of alteration as a result of repetition finds its way in drawings of optic nerves and Ruffini endings. (merpaperkunsthalle.org)
- Sensory nerve endings in the fingers include Meisnner's corpuscles (light touch, rapidly adapting) , Pacinian corpuscles (large receptive fields, rapidly adapting), free nerve endings (temperature and pain), Merkel discs (light touch discrimination of objects and texture), and Ruffini endings (slowly adapting, finger position information). (anthropogeny.org)
- Occasionally, the existence of an outer collagenous capsule is used to differentiate different types of sensory receptors (Malinovsky, 1996), for example, Ruffini endings that possess an outer capsule vs. Ruffini-like endings that do not (see section on Ruffini-like endings, below). (scholarpedia.org)
Neurons5
- The human brain is estimated to have 100 billion neurons or nerve cells. (deccanherald.com)
- NGF may act by increasing substance P release from sensory nerve endings, without upregulation of substance P in the neurons. (kuleuven.be)
- The current study investigated a glial cell that encases the nerve endings of 12 different neurons in the roundworm Caenorhabditis elegans . (neuro-central.com)
- RTX isn't going to destroy the endings of all these neurons willy-nilly. (wired.com)
- Particularly germane to this report is the dense innervation of the follicle by a large variety of nerve fibers provided by sensory neurons of the trigeminal ganglia (Fig. 1, inset). (scholarpedia.org)
Afferent13
- A free nerve ending ( FNE ) or bare nerve ending , is an unspecialized, afferent nerve fiber ending of a sensory neuron . (wikipedia.org)
- A single afferent nerve fibre branches to innervate up to 90 such endings. (bionity.com)
- In mammals, electrical recordings from single afferent nerve fibres have shown that the responses Merkel nerve endings are characterized by a vigorous response to the onset of a mechanical ramp stimulus (dynamic), and then continued firing during the plateau phase (static). (bionity.com)
- A free nerve ending ( FNE ) is an unspecialized, afferent nerve ending, meaning it brings information from the body's periphery to the brain. (wikidoc.org)
- A simple and novel technique for recording afferent discharge due to mechanical stimulation of lanceolate terminals of palisade endings innervating mouse ear skin hair follicles is presented. (jove.com)
- Sensory nerves, or afferent nerves, carry information from the periphery of the body to the brain and spinal cord. (thefreedictionary.com)
- comprise afferent and efferent endings. (thefreedictionary.com)
- Four distinct morphological types of spinal afferent ending in the bladder were identified. (edu.au)
- The majority of spinal afferent nerve endings were CGRP-immunoreactive. (edu.au)
- Single spinal afferent axons bifurcated many times upon entering the bladder and developed varicosities along their axon terminal endings. (edu.au)
- We present the first morphological identification of spinal afferent nerve endings in the mammalian urinary bladder. (edu.au)
- The sensory endings of a primary (group Ia) afferent and a secondary (group II) afferent coil around the non-contractile central portions of the intrafusal fibres. (wikipedia.org)
- They convey length information to the central nervous system via afferent nerve fibers . (wikipedia.org)
Dermis2
- The free nerve endings occur within all layers of the connective tissue, but mainly in the papillary layer of the dermis. (springer.com)
- The perception of the speed at which any substance moves across skin is a function of the nerve fibres within the dermis and the texture of the material involved. (cosmosmagazine.com)
Spinal16
- Spinal cord stimulator also helps control pain in some cases while in others it causes symptoms similar to those experienced after nerve burning. (medhelp.org)
- The Spinal cord nerve ending model illustrates the composition of the spinal cord, magnified to a scale of about 5:1. (shopanatomical.com)
- The Spinal Cord with Nerve Endings model is supplied on a base. (shopanatomical.com)
- This Spinal Cord with Nerve Endings model is a great tool for teaching the anatomy of the human nervous system. (shopanatomical.com)
- Motor nerves, or efferent nerves, transmit impulses from the brain and spinal cord to the periphery, especially the muscles. (thefreedictionary.com)
- Together, the nerves make up the peripheral nervous system, as distinguished from the central nervous system, which consists of the brain and spinal cord. (thefreedictionary.com)
- Spinal nerves arise from the spinal cord and pass out between the vertebrae. (thefreedictionary.com)
- Although the location of the nerve cell bodies of spinal afferents is well known to reside in dorsal root ganglia (DRG), the morphology and location of peripheral nerve endings of spinal afferents that transduce sensory stimuli into action potentials is poorly understood. (edu.au)
- The individual nerve endings of spinal afferents that innervate the urinary bladder have never been unequivocally identified in any species. (edu.au)
- Mu (μ) receptors are found on the sensory nerve endings in the peripheral nervous system as well as in the spinal cord, the brain, the gut and many other places. (findanyanswer.com)
- Nervous tissue is found in the brain , spinal cord , and nerves. (findanyanswer.com)
- Peripheral neuropathy, a result of damage to the nerves outside of the brain and spinal cord (peripheral nerves ), often causes weakness, numbness and pain , usually in your hands and feet . (findanyanswer.com)
- The degenerating disc can cause structural changes nearby, such as the narrowing of a nerve pathway which causes spinal stenosis and may result in radicular pain . (spine-health.com)
- even chronically demyelinated areas of the optic nerve and spinal cord can be symptom free. (nih.gov)
- Until now the regeneration of nerve cells - or neurones - in the brain and the spinal column has been considered impossible. (telegraph.co.uk)
- These proteins, they discovered, were produced in large quantities after a spinal injury and formed a scar, described as an impenetrable wire fence, around the damaged nerve endings, preventing messages being transmitted to the brain. (telegraph.co.uk)
Motor nerve5
- 4. In other animals Henle's sheath extends over the end fibres of the motor nerve and the cells lining it envelop the end fibrils. (rupress.org)
- Showing intercostal muscles and motor nerve plates. (wardsci.com)
- 3. Based on the experimental and cadeveric results, free vascularized long nerve grafts and vascularized muscle transfer with a long motor nerve have been clinically developed for repair of untreatable established nerve paralysis. (nii.ac.jp)
- Immunohistochemical analysis has demonstrated presence of the α 3 nAChR subunit at the presynaptic motor nerve ending. (asahq.org)
- This slide is a whole-mount of motor nerve endings and plates from a mammal. (gosciencecrazy.com)
Fibres11
- Aside from the surfaces of contact of muscle and nerve fibre, the end fibres are covered down to their tips with the sheath of Schwann and are provided with nuclei. (rupress.org)
- Properly interpreted it demonstrates that the nerve fibres that are to influence the muscle fibre are not naked and that they need not be end fibres. (rupress.org)
- 5. The terminal nerves in smooth muscle form a network entwining the bundles of muscle fibres. (rupress.org)
- From this network fine, nucleated, nerve fibres pass to the walls of the capillaries, with which they are very closely united. (rupress.org)
- The intragemmal nerve fibres show knotty swellings of various sizes and shapes. (eurekamag.com)
- Parvalbumin-immunoreactive nerve fibres were most abundant in the lingual periodontal ligaments of incisor teeth. (elsevier.com)
- In the part of the ligament adjacent to the alveolar bone, thick and smooth parvalbumin-immunoreactive nerve fibres left main nerve bundles and passed towards the part of the ligament adjacent to the tooth. (elsevier.com)
- In the ligament, halfway between the bone and tooth surfaces, these nerve fibres repeatedly branched and extended one to four twigs to produce bush-like endings. (elsevier.com)
- The monkey studies revealed that a particular type of nerve cell tissues - called Pacinian corpuscle -associated (PC) fibres - were triggered by movement across the skin. (cosmosmagazine.com)
- In summary," they write, "the firing rates of tactile nerve fibres systematically increase with increasing speed, but the perceptual sensitivity to speed and the dependence of perceived speed on surface texture seem to reflect PC firing rates. (cosmosmagazine.com)
- Primary type Ia sensory fibers (large diameter) spiral around all intrafusal muscle fibres, ending near the middle of each fibre. (wikipedia.org)
Pacinian1
- Free nerve endings are unencapsulated and have no complex sensory structures, unlike those found in Meissner's or Pacinian corpuscles . (wikidoc.org)
Fibers15
- The majority of Aδ (A delta) fibers (group III) and C (group IV) fibers end as free nerve endings. (wikipedia.org)
- a form of peripheral ending of sensory nerve fibers in which the terminal filaments end freely in the tissue. (drugs.com)
- What is a bundle of nerve fibers called? (reference.com)
- A bundle of nerve fibers is referred to as a tract in the nervous system. (reference.com)
- Nerve fibers can also be referred to as a lumbosacral plexus or a complex network. (reference.com)
- The results obtained support the hypothesis that both NE and 5-HT coexist in the nerve vesicles of pineal adrenergic fibers. (aspetjournals.org)
- a macroscopic cordlike structure of the body, comprising a collection of nerve fibers that convey impulses between a part of the central nervous system and some other body region. (thefreedictionary.com)
- Mixed nerves are composed of both motor and sensory fibers, and transmit messages in both directions. (thefreedictionary.com)
- The various nerve fibers and cells that make up the autonomic nervous system innervate the glands, heart, blood vessels and involuntary muscles of the internal organs. (thefreedictionary.com)
- Only 60% of the axons in the nerve to a given muscle are motor to the muscle fibers that make up the bulk of the muscle. (medscape.com)
- The nerve supply branches within the muscle belly, forming a plexus from which groups of axons emerge to supply the muscle fibers. (medscape.com)
- The pain experience for all of us begins when unpleasant stimuli activate sensory nerve fibers called nociceptors. (findanyanswer.com)
- Most of Ad fibers and C fibers end as free nerves endings. (biologiedelapeau.fr)
- With continued degradation, the nerve fibers on the periphery of the disc will actually grow further into the disc space. (spine-health.com)
- It remains to be seen whether a lack of sensory nerve fibers in the hand of non-human hominids contributes to the lack of tool use in those species. (anthropogeny.org)
Hair follicles4
- Merkel nerve endings are found in the basal layer of glabrous and hairy skin, in hair follicles , and in oral and anal mucosa. (bionity.com)
- The system is suitable for assaying the electrophysiological and optical properties of lanceolate terminals of palisade endings of hair follicles, as well as the outcomes from their pharmacological and/or genetic manipulation. (jove.com)
- The innervation of hair follicles in such a preparation is less complex but the density of the hair follicles, plus the presence of three different follicle types (guard, Awl/auchene and zigzag hairs) in such close proximity 6 , means studying the specific responses of a single follicle or single type of ending is again challenging. (jove.com)
- There are also sensory nerves encircling hair follicles that give information on when the hair is displaced. (anthropogeny.org)
Stimuli2
- Free nerve endings can detect temperature, mechanical stimuli (touch, pressure, stretch) or danger ( nociception ). (wikipedia.org)
- These nerve endings are responsible for detecting temperature, mechanical stimuli (such as pressure), pain (nociception), and information about touch. (wikidoc.org)
Presynaptic6
- 4 Recently, it was demonstrated that a selective block of the α 3 β 2 nAChR in an in vitro nerve-muscle preparation reduced the presynaptic acetylcholine release, and furthermore caused tetanic fade after a magnesium-induced reduction of the safety factor of synaptic transmission. (asahq.org)
- These results have demonstrated that Aβ peptides can acutely inhibit the depolarization-evoked release of ACh by acting directly on cholinergic presynaptic nerve endings. (lu.se)
- Because Slc4a8 was found to predominantly localize to presynaptic nerve endings, we hypothesize that Slc4a8 is a key regulator of presynaptic pH. (jneurosci.org)
- Here, we show that Slc4a8 was enriched in presynaptic glutamatergic nerve endings and, indeed, played an essential role in the regulation of intracellular pH (pH i ). (jneurosci.org)
- At electrical synapses , which are relatively rare in vertebrates, the membranes of the two cells are in tight contact, producing electrical coupling, which enables a nerve impulse (or action potential ) arriving at the presynaptic nerve ending to pass swiftly and reliably to the next cell. (encyclopedia.com)
- The cytoplasm of the presynaptic nerve terminal (in a chemical synapse) is packed full of small vesicles, each containing a few thousand molecules of neurotransmitter. (encyclopedia.com)
Mammalian1
- The data clearly demonstrate that in mammalian neurosecretory nerve endings tetanus toxin acts at a step downstream from the activation by Ca2+ of the exocytotic machinery and that the functional domain of this toxin is confined to its light chain. (uni-muenchen.de)
Merkel8
- Merkel nerve endings are mechanoreceptors found in the skin and mucosa of vertebrates that provide touch information to the brain . (bionity.com)
- Each ending consists of a Merkel cell in close apposition with an enlarged nerve terminal . (bionity.com)
- In mammals, Merkel nerve endings have a wide distribution. (bionity.com)
- Because of their sustained response to pressure, Merkel nerve endings are classified as slowly adapting. (bionity.com)
- Merkel nerve endings are extremely sensitive to tissue displacement, and may respond to displacements of less than 1 μm. (bionity.com)
- For this reason, Merkel nerve endings and Meissner's corpuscles are most densely clustered in the highly sensitive finger tips, and less so in the palms. (bionity.com)
- It uses material from the Wikipedia article "Merkel_nerve_ending" . (bionity.com)
- Each type of mechanoreceptor has a characteristic morphology (see Merkel or lanceolate endings Figs. 1 and 2). (scholarpedia.org)
Terminal6
- Horizontal axons developed into families of leashes with disorganized terminal branches and endings. (nih.gov)
- I consider it improbable that each plain muscle fibre has a special terminal nerve fibril. (rupress.org)
- We have used synaptosomes and glial plasmalemmal vesicles (GPV) from adult mouse and rat CNS to identify the nerve terminal transporter. (nih.gov)
- The data presented in this study indicate that EAAT2 is the predominant nerve terminal glutamate transporter in the adult rodent CNS. (nih.gov)
- 4. To further investigate the involvement of sensory nerve endings we used the cannabinoid receptor 1 (CB(1)) agonist R-methanandamide to inhibit excitatory events at the nerve terminal. (kuleuven.be)
- Il est possible que le Nerve Ending soit un axone géant, un terminal d'impulsions électriques pour cellules nerveuses, ce qui explique son nom. (gamepedia.com)
Penis12
- Halata Z., Johnson R.B., Kitchell R.L., Strasmann T. (1988) The Ultrastructure of Sensory Nerve Endings in the Penis of the Goat. (springer.com)
- Do water penis enlarged nerve endings on the penis pumps work. (yfairproductions.nl)
- Penis enlarge pump enlarged nerve endings on the penis use. (yfairproductions.nl)
- What is enlarged nerve endings on the penis the best penis pill. (yfairproductions.nl)
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- enlarged nerve endings on the cronw of the penis How to size your penis. (jocelyneberoard.be)
- Does your penis enlarged nerve endings on the cronw of the penis get bigger when you lose weight. (jocelyneberoard.be)
- Male enhancement ad on sirius enlarged nerve endings on the cronw of the penis fantasy sports call in number. (jocelyneberoard.be)
- Male breast enlarged nerve endings on the cronw of the penis enhancement hormones. (jocelyneberoard.be)
- Hollywood enlarged nerve endings on the cronw of the penis nails titan active gel. (jocelyneberoard.be)
- Whether you have a penis or a vagina, there are tons of nerve endings located at the entry of the bum. (elitedaily.com)
Regenerate3
- As far as the nerve endings, someone on this forum mentioned that nerves regenerate at the rate of 1/2 inch per month, what exactly that leads to I don't know. (healingwell.com)
- However, because the hydrogel expands in water and fluids, the expansion would collapse the tunnel and reduce the ability of the nerve endings to regenerate and connect, [Mohammad Reza Abidian, assistant professor of biomedical engineering, Penn State], said. (medgadget.com)
- moment for a French biologist working to regenerate severed nerve endings, reports Kim Willsher in Paris. (telegraph.co.uk)
Free12
- Free nerve endings are unencapsulated and have no complex sensory structures. (wikipedia.org)
- Free nerve endings have different rates of adaptation, stimulus modalities , and fiber types . (wikipedia.org)
- Thus, different free nerve endings work as thermoreceptors , cutaneous mechanoreceptors and nociceptors . (wikipedia.org)
- free nerve endings, 2. (springer.com)
- How would you define free nerve ending? (azdictionary.com)
- Free nerve ending have different rate of adaptation, stimulus modalities and fiber types. (academic.ru)
- The commonest form of the intra-epithelial nerve endings belongs to a simple or unbranched type of free endings, but in the papilla foliata nerves often show ramified and complicated endings. (eurekamag.com)
- Publications] Koshima Isao: 'Free vascularized deep peroneal nerve grafts. (nii.ac.jp)
- Includes unlimited streaming of NERVE'S ENDING via the free Bandcamp app, plus high-quality download in MP3, FLAC and more. (lapfoxtrax.com)
- The surface of the body -the skin- contains very large numbers of the free nerve endings known as nociceptors, which is why it is so sensitive to pain. (findanyanswer.com)
- I believe that people of all genders should take a shame-free approach to discovering as many of these nerve endings as possible. (elitedaily.com)
- Sensory nerve endings are divided into two groups morphologically: mechanoreceptors and free nerve endings (Fig. 1, inset). (scholarpedia.org)
Receptors6
- Phasic and tonic receptors are two types of endings of sensory nerve cells. (reference.com)
- There are several sensory nerve endings and receptors in the human hand. (anthropogeny.org)
- Rapidly-adapting nerve receptors deliver information on changes that occur at the skin, such as occurs as you move your finger over a gritty surface. (anthropogeny.org)
- Human specific differences that mediate enhanced fine motor control might instead rely more heavily on muscular and bone differences rather than differences in sensory nerve receptors. (anthropogeny.org)
- At nerve-muscle synapses, and in many nerve-nerve synapses, the receptors have a double function, since they also serve as ion channels . (encyclopedia.com)
- Sensory nerve endings are synonymous with "sensory receptors. (scholarpedia.org)
Cranial nerves1
- There are 12 pairs of cranial nerves, which carry messages to and from the brain. (thefreedictionary.com)
SILVERSUN PICKUPS2
- Bloody Mary (Nerve Endings)", often referred to as just "Bloody Mary", is an indie rock song performed by American alternative rock music group Silversun Pickups. (wikipedia.org)
- Brian Aubert - guitar, vocals Chris Guanlao - drums Joe Lester - keys Nikki Monninger - bass, vocals "Ultratop.be - SILVERSUN PICKUPS - BLOODY MARY (NERVE ENDINGS)" (in Dutch). (wikipedia.org)
Axon1
- a process of a neuron, especially the long slender axon which conducts nerve impulses away from the cell. (thefreedictionary.com)
Sweat glands1
- The soles of your feet contain more sweat glands and sensory nerve endings per square centimeter than any other part of the body. (findanyanswer.com)
Morphology1
- Most nerve endings were located in detrusor muscle where the three types could be identified as having: 'branching', 'simple', or 'complex' morphology. (edu.au)
Mechanoreceptors1
- It is possible that parvalbumin-immunoreactive endings are periodontal mechanoreceptors, but at present it is difficult to account for the different representations around rat molar and incisor teeth. (elsevier.com)
Muscle12
- The researchers tested the three designs - plain hydrogel, hydrogel with fully-coated PEDOT wall, and hydrogel with a partially coated PEDOT wall - by implanting the device in 10 mm nerve gaps in rats and measuring the muscle mass and strength of muscle contractions at the end of the nerves. (medgadget.com)
- 1. The endings of the motor nerves in striped muscle remain on the outside of the sarcolemma. (rupress.org)
- The precise condition of things at the places of contact of muscle and nerve is an unsolved problem of histology. (rupress.org)
- 2. The ivy-like or festooned arrangement of motor nerves in the frog's muscle has been misinterpreted. (rupress.org)
- It shows that mere contact between muscle fibre and nerve fibre is all that is necessary. (rupress.org)
- These nerves also relay information to the brain about the positions of joints, muscle tension and speed of movements. (reference.com)
- Periodical changes of muscle cells and peripheral sensory nerve endings after denervation. (nii.ac.jp)
- 1. Experimentally, it was observed that regeneration following degeneration of the gastrocunemius muscle cells after rat's sciatic nerve transection. (nii.ac.jp)
- A clitoris is made up of 18 distinct parts - a mixture of erectile tissue, muscle and nerves . (findanyanswer.com)
- There's a lot of muscle and thick skin on your forearms, without many nerve endings. (findanyanswer.com)
- synapse A specialized junction where transmission of information takes place between a nerve fibre and another nerve cell, or between a nerve fibre and a muscle or gland cell. (encyclopedia.com)
- Acetylcholine is the excitatory transmitter at nerve-muscle synapses, and glutamate is the main excitatory transmitter in the central nervous system . (encyclopedia.com)
Bloody Mary1
- Bloody Mary (Nerve Endings) is off of their upcoming album Neck of the Woods out May 8. (blogspot.com)
Dorsal2
- They tingle/throb constantly at the tip(nasal dorsal nerve? (medhelp.org)
- The nerve supply in the posterior part of the corpus linguae and in the dorsal part of the apex linguae is much denser than in the anterior part of the corpus linguae, the inferior surface of the whole tongue, and the dorsal part of the tongue root. (eurekamag.com)
Brain3
- Nerve signals in the foot transmit information to the brain about the safety of the walking surface and the position of the foot relative to the surface. (reference.com)
- The reaction of colloidal iron hydroxide (CIH) with acidic groups was applied for an ultra-structural study of the distribution of sulphuric acid monoesters and sialic acid in synaptic vesicles and external nerve ending membranes isolated from rat brain. (biologists.org)
- Nerve endings are points on the surface of your body that are responsible for sending messages to your brain when you feel sensations such as heat, cold, pain, and pleasure,' says Sinclair. (elitedaily.com)
Blood-vessels1
- 7. The nerves supplying the capillaries connect also with sensory nerves and with nerves surrounding the larger blood-vessels, both arteries and veins. (rupress.org)
Slowly2
- They are a mix of rapidly and slowly adapting endings that predominantly produce short bursts of activity in response to hair movement. (jove.com)
- Other types of nerve cells - in families known as "rapidly adapting" and "slowly adapting" - also increased activity in response to speed, but in less pronounced and less consistent manners. (cosmosmagazine.com)
Dopamine3
- Methamphetamine intoxication causes long-lasting damage to dopamine nerve endings in the striatum. (aspetjournals.org)
- We report here that methamphetamine activates microglia in a dose-related manner and along a time course that is coincident with dopamine nerve ending damage. (aspetjournals.org)
- MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine), which damages dopamine nerve endings and cell bodies, causes extensive microglial activation in striatum as well as in the substantia nigra. (aspetjournals.org)
Terminals6
- The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland. (uni-muenchen.de)
- Most CNS glutamate uptake is mediated by EAAT2 into glia, though nerve terminals show evidence for uptake, through an unknown transporter. (nih.gov)
- The IC50 values found for these compounds suggested functional expression of the 'glial, transporter, EAAT2 in nerve terminals. (nih.gov)
- The thin underlying dermal layer gives good accessibility to the nerve terminals with pharmacological drugs and dyes. (jove.com)
- These have taught us much about the general principles of mechanosensory physiology in the nerve terminals surrounding the hair shaft. (jove.com)
- It used to be thought that each nerve fibre releases only one neurotransmitter ('Dale's principle', after the British pharmacologist, Henry Dale), but it is now known that two or more transmitters and/or modulators can be produced by individual nerve terminals. (encyclopedia.com)
Tibial2
- Publications] Koshima Isao: 'The combined anterior and posterior tibial perforator‐based flap with a vascularized deep peroneal nerve for repair of facial defect. (nii.ac.jp)
- In dogs, the common peroneal, ulnar and tibial nerves are the usual sources. (thefreedictionary.com)
Stimulation5
- Most of the nerve endings involved in sexual stimulation in a woman are in the clitoris. (lavistachurchofchrist.org)
- The vagina itself doesn't have many nerve endings, almost all the stimulation from sex comes from the various connections to the clitoris being pulled on during sex. (lavistachurchofchrist.org)
- 1. an inhibitory nerve whose stimulation depresses a motor center. (thefreedictionary.com)
- Sinclair says, 'There's a common misconception that anal play always end in anal penetration, but wearing a small butt plug like our Novice Plug can add an amazing amount of extra stimulation to the sensitive nerve endings located at the entry of the anal canal. (elitedaily.com)
- It is a type of a vascular headache Of unknown aetiology In which final step of pathology of pain is constriction (producing the neurological symptoms of the prodroma and the aura) followed by diltation of one or more of branches of carotid artery or vertebrobasilar arteries Leading to stimulation of pain nerve endings surrounding artery by stretching -- producing the headache). (scribd.com)
Pain16
- Nerve burning/nerve freezing/nerve block procedure do help control pain. (medhelp.org)
- The mouse skin/saphenous nerve preparation is most often used in its depilated state to investigate touch and pain responses. (jove.com)
- Feels as though nerve endings reach down into my head/cause travelling pain. (healthtap.com)
- Sensations of heat, cold, pressure and pain are conveyed by the sensory nerves. (thefreedictionary.com)
- The pain caused by pressure on the trigeminal nerve has been described as the most agonising known to humankind, but what does the nerve actually do? (findanyanswer.com)
- What causes nerve pain in feet and hands? (findanyanswer.com)
- If a tear in the annulus fibrosus reaches the outer edge, the nerves there can become sensitized and cause significant spine pain. (spine-health.com)
- The growth of nerves may be associated with pain from a degenerating disc. (spine-health.com)
- If the nucleus pulposus, which contains a great deal of inflammatory proteins, leaks out of the disc and touches a nerve root, that nerve root can become inflamed and cause pain that radiates down a leg ( sciatica or lumbar radiculopathy ) or down an arm ( cervical radiculopathy ). (spine-health.com)
- Disc pain may be caused by several factors acting simultaneously, usually involving nerves that penetrate deep into the disc's outer edge or involving the instability of the disc after an injury. (spine-health.com)
- Inject RTX, as it's known, into an aching joint, and it'll actually destroy the nerve endings that signal pain. (wired.com)
- Instead, it binds to a major molecule in specifically pain-sensing nerve endings, called TRPV1 (pronounced TRIP-vee one). (wired.com)
- That's toxic, leading to the inactivation of the pain-sensing nerve endings. (wired.com)
- What is involved in burning nerve endings to relieve pain? (reference.com)
- Patients with specific patterns of referred pain (trigger points), indication of blood vessel, lymph, nerve entrapment or proprioceptive disturbances (balance) should be evaluated for MPS. (tripod.com)
- Many such foods contain tyramine, a natural food chemical that transmits signals along pain nerve endings. (wsj.com)
Peripheral nerves2
- Aims Lidocaine makes analgesia by inhibiting excitation of nerve endings or blocking impulse conduction in peripheral nerves. (bioskinrevive.com)
- In gross anatomy, the nerves to skeletal muscles are branches of mixed peripheral nerves. (medscape.com)
Cell bodies2
- In these rings sensory nerve endings are present, but these endings lack any contact with their cell bodies. (kuleuven.be)
- 5. This indicates that NGF can induce an increase in airway responsiveness in the absence of sensory nerve cell bodies. (kuleuven.be)
Uptake1
- Greene LA, Rein G (1977a) Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor ( NGF) response pheochromocytoma cell. (springer.com)
Synaptosomes1
- Preparations of synaptosomes (P 2 ) from the telencephalon and from the diencephalon plus optic lobes of the pigeon and from the telencephalon of the rat were used to study the effects of 5 hydroxytryptophan (5 HTP) on the levels of serotonin (5 HT) in nerve endings and the release of 5 HT from nerve endings. (elsevier.com)
200,0002
- The more than 200,000 nerves in the feet also exist to aid in walking with proper movement, according to New York. (reference.com)
- The soles of the feet are extremely sensitive to touch due to a high concentration of nerve endings, with as many as 200,000 per sole. (findanyanswer.com)
Glabrous1
- However, it is the sensory nerve endings on glabrous (non-hairy) skin that likely contribute to the proprioceptive and tactile control necessary for fine touch discrimination and tool use. (anthropogeny.org)
Tissue4
- 6. In muscular tissue fine non-medullated nerves, probably belonging to the centrifugal, vasomotor system, proceed from the fasciculi of motor nerves. (rupress.org)
- Investigate Nerve Tissue. (wardsci.com)
- The irritation often causes the nerves to enlarge and noncancerous (benign) growths of nerve tissue (neuromas) to form, usually between the base of the third and fourth toes (Morton neuroma). (findanyanswer.com)
- They constantly sway back and forth and appear to be attached to a small pile of organ tissue on the ground with smaller Nerve Endings protruding. (gamepedia.com)
Neural2
- These neural symptoms are a challenging thing to treat as careful examination is needed to ascertain the level of nerve involvement. (healthcaremagic.com)
- It has already been suggested that glial cells may possess the ability to manipulate the shape of nerve endings and mold the function of neural cells, however, the mechanisms for such alterations remain, for the most part, unknown. (neuro-central.com)
Receptor1
- Since antagonizing the neurokinin-1 (NK(1)) receptor can prevent this NGF-induced airway hyperresponsiveness and since sensory nerves release tachykinins, we investigated the role of sensory nerves in the NGF-induced airway hyperresponsiveness. (kuleuven.be)
TRPV11
- When RTX binds to TRPV1, it props open the nerve cell's ion channel, letting a whole lot of calcium in. (wired.com)
Epithelium1
- Wherever they are found, the epithelium is arranged to optimize the transfer of pressure to the ending. (bionity.com)
Bundles1
- Bundles of nerve processes within the central nervous system are called fasciculi, tracts or funiculi, depending upon their size. (reference.com)
Sensory feedback2
- The thousands of nerve endings in the human foot supply sensory feedback to the central nervous system, according to the Canadian Federation of Podiatric Medicine. (reference.com)
- The ability to throw and club effectively contributes to all of the above pursuits and likely involves proprioceptive and sensory feedback from sensory nerve endings. (anthropogeny.org)
Medial1
- The two largest nerves in the bottom of the foot, the medial and lateral plantar nerves, work together to control the small foot and toe muscles, according to InnerBody. (reference.com)
Trigeminal1
- trigeminal nerve . (findanyanswer.com)
Types3
- Three types of nerve endings were observed: 1. (springer.com)
- However, it can be difficult to decipher the output due to its complexity, as vibrissal follicles contain at least 8 different types of anatomically distinct mechanosensory ending 5 and the matching of these morphological types to specific electrophysiological responses is still a matter of dispute. (jove.com)
- A further study by the same group, published in Cell Reports , indicates that glial cells in C.elegans alter the shape of many different types of nerve endings, pointing to many other molecular mechanisms that have not yet been discovered. (neuro-central.com)