Formation of stones in the KIDNEY.
Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.
The calcium salt of oxalic acid, occurring in the urine as crystals and in certain calculi.
Excretion of abnormally high level of CALCIUM in the URINE, greater than 4 mg/kg/day.
Excretion of an excessive amount of OXALATES in the urine.
A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.
Formation of stones in any part of the URINARY TRACT, usually in the KIDNEY; URINARY BLADDER; or the URETER.
An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
Disorders in the processing of calcium in the body: its absorption, transport, storage, and utilization.
Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
A plant genus of the family LAMIACEAE that contains pimarane-type diterpenes. Several species of Orthosiphon are also called Java tea.
An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.
The sole species of the genus Oxalobacter consisting of straight or curved gram-negative rods with rounded ends. Cells are nonmotile, nonsporing, and use oxylates as the only source of CARBON and energy, with formate and CARBON DIOXIDE as end products. They are isolated from lake sediments and from the rumen or large bowel of humans and animals. (From Bergey's Manual of Determinative Bacteriology, 9th ed)
Endoscopic examination, therapy or surgery of the ureter.
A genetic disorder characterized by excretion of large amounts of OXALATES in urine; NEPHROLITHIASIS; NEPHROCALCINOSIS; early onset of RENAL FAILURE; and often a generalized deposit of CALCIUM OXALATE. There are subtypes classified by the enzyme defects in glyoxylate metabolism.
Genetic defects in the selective or non-selective transport functions of the KIDNEY TUBULES.
A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
A glycosyl-phosphatidyl-inositol (GPI) - anchored membrane protein found on the thick ascending limb of the LOOP OF HENLE. The cleaved form of the protein is found abundantly in URINE.
A powder that dissolves in water, which is administered orally, and is used as a diuretic, expectorant, systemic alkalizer, and electrolyte replenisher.
A class of G-protein-coupled receptors that react to varying extracellular CALCIUM levels. Calcium-sensing receptors in the PARATHYROID GLANDS play an important role in the maintenance of calcium HOMEOSTASIS by regulating the release of PARATHYROID HORMONE. They differ from INTRACELLULAR CALCIUM-SENSING PROTEINS which sense intracellular calcium levels.
A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.
A family of monosaccharide transport proteins characterized by 12 membrane spanning helices. They facilitate passive diffusion of GLUCOSE across the CELL MEMBRANE.
A chronic inflammatory condition of the KIDNEY resulting in diffuse renal destruction, a grossly enlarged and nonfunctioning kidney associated with NEPHROLITHIASIS and KIDNEY STONES.
A non-electrogenic sodium-dependent phosphate transporter. It is found primarily in apical membranes of PROXIMAL RENAL TUBULES.
A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION.
A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
Hereditary metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of uric acid calculi.
A condition of an abnormally low level of PHOSPHATES in the blood.
The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.
The destruction of a calculus of the kidney, ureter, bladder, or gallbladder by physical forces, including crushing with a lithotriptor through a catheter. Focused percutaneous ultrasound and focused hydraulic shock waves may be used without surgery. Lithotripsy does not include the dissolving of stones by acids or litholysis. Lithotripsy by laser is LITHOTRIPSY, LASER.
Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA.
Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.
Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
Directions or principles presenting current or future rules of policy for assisting health care practitioners in patient care decisions regarding diagnosis, therapy, or related clinical circumstances. The guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by the convening of expert panels. The guidelines form a basis for the evaluation of all aspects of health care and delivery.
Societies whose membership is limited to physicians.
Conformity in fulfilling or following official, recognized, or institutional requirements, guidelines, recommendations, protocols, pathways, or other standards.
A voluntary organization concerned with the prevention and treatment of cancer through education and research.
A systematic statement of policy rules or principles. Guidelines may be developed by government agencies at any level, institutions, professional societies, governing boards, or by convening expert panels. The text may be cursive or in outline form but is generally a comprehensive guide to problems and approaches in any field of activity. For guidelines in the field of health care and clinical medicine, PRACTICE GUIDELINES AS TOPIC is available.
A plant genus of the family RUTACEAE. They bear the familiar citrus fruits including oranges, grapefruit, lemons, and limes. There are many hybrids which makes the nomenclature confusing.
Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
The renal tubule portion that extends from the BOWMAN CAPSULE in the KIDNEY CORTEX into the KIDNEY MEDULLA. The proximal tubule consists of a convoluted proximal segment in the cortex, and a distal straight segment descending into the medulla where it forms the U-shaped LOOP OF HENLE.
A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.

Factors increasing the risk for stone formation in adult patients with cystic fibrosis. (1/120)

BACKGROUND: Patients with cystic fibrosis (CF) are at high risk of nephrolithiasis (NL), but controversy still exists in terms of causes, including low urine output, hypercalciuria, hyperoxaluria, hyperuricosuria and hypocitraturia. Moreover, heterozygotes (H-CF), which may exhibit altered renal concentrating and diluting ability, have never studied so far. We, therefore, evaluated the metabolic and physicochemical data of adult CF and H-CF patients, comparing them to controls (C). METHODS: Twenty-nine CF patients (16 females, aged 28.4 +/- 7.1 years), 20 H-CF (12 females, aged 58.6 +/- 6.3 years) and 30 C (19 females, aged 39.1 +/- 11.5 years) underwent kidney ultrasound and metabolic evaluation to assess stone risk profile. RESULTS: There was a 21% prevalence of NL in CF vs 15% in H-CF. The CF group had elevated uric acid, but no other serological differences compared with the H-CF and C group. Conversely, the citrate and oxalate content in the urine differed significantly, being lower and higher, respectively. These changes held after correction for urine creatinine. Consequently, urine specimens were more supersaturated with calcium oxalate, despite exhibiting no differences for other relevant constituents. Uric acid increased only after normalization for the body weight and urine creatinine. Lower urine volume and more acidic pH produced mild supersaturation with uric acid in samples from CF, while urine from both H-CF and C remained undersaturated. H-CF had only minor increases in both urine oxalate and calcium oxalate supersaturation. CONCLUSIONS: This study confirms a high prevalence of kidney stones among CF patients associated with supersaturated urine. Their longer survival justifies diets and/or medications aimed at reducing the risk of forming stones.  (+info)

Crystal retention in renal stone disease: a crucial role for the glycosaminoglycan hyaluronan? (2/120)

The mechanisms that are involved in renal stone disease are not entirely clear. In this article, the various concepts that have been proposed during the past century are reviewed briefly and integrated into current insights. Much attention is dedicated to hyaluronan (HA), an extremely large glycosaminoglycan that may play a central role in renal stone disease. The precipitation of poorly soluble calcium salts (crystal formation) in the kidney is the inevitable consequence of producing concentrated urine. HA is a major constituent of the extracellular matrix in the renal medullary interstitium and the pericellular matrix of mitogen/stress-activated renal tubular cells. HA is an excellent crystal-binding molecule because of its size, negative ionic charge, and ability to form hydrated gel-like matrices. Crystal binding to HA leads to crystal retention in the renal tubules (nephrocalcinosis) and to the formation of calcified plaques in the renal interstitium (Randall's plaques). It remains to be determined whether one or both forms of renal crystal retention are involved in the development of kidney stones (nephrolithiasis).  (+info)

R990G polymorphism of the calcium-sensing receptor and renal calcium excretion in patients with primary hyperparathyroidism. (3/120)

CONTEXT: Primary hyperparathyroidism (PHPT) shows a great variability in clinical course and severity. Data concerning the association between polymorphic variants of the gene encoding the calcium-sensing receptor (CaSR) and clinical characteristics of PHPT are not conclusive. OBJECTIVE: To evaluate the frequency of three polymorphisms; A986S, R990G, and Q1011E of CaSR in patients with PHPT and to correlate the genotypes with clinical and biochemical parameters. PATIENTS AND METHODS: The study included 94 consecutive unrelated patients referred to our Departments for PHPT diagnosis and management between 2000 and 2005 and 137 age and sex-matched healthy subjects. Patients and controls were genotyped according to standard procedures. Due to the rarity of 990G allele, homozygous and heterozygous subjects were grouped in R/G+G/G set. All PHPT patients were studied for calcium metabolism parameters and renal and bone complications. RESULTS: The proportion of CaSRvariants was similar in PHPT patients and controls. In PHPT patients, only R990G polymorphism was associated with disease parameters; in comparison with R/R, R/G+G/G patients showed lower mean serum parathyroid hormone (PTH) and phosphate levels (139.9 +/- 62.2 vs 199.9 +/- 136.3 pg/ml, P < 0.05 and 0.69 +/- 0.12 vs 0.81 +/- 0.18 mmol/l, P = 0.031 respectively), higher mean 24-h urine calcium concentration and calcium excretion (9.05 +/- 2.05 vs 6.77 +/- 4.31 mmol/24 h, P = 0.012 and 67 +/- 20 vs 51 +/- 26 mumol/l GF, P = 0.039), and increased prevalence of nephrolithiasis (90.0 vs 44.2%, P = 0.007). CONCLUSIONS: The study showed that patients with PHPT, bearing the 990G allele, had lower serum PTH levels and higher urinary calcium excretion in comparison with the other genotype, suggesting an increased sensitivityof the variant receptor to extracellular calcium. Since this variant was associated with increased occurrence of nephrolithiasis, analysis of this polymorphism might help to predict renal complication of the disease.  (+info)

Proteomics in renal research. (4/120)

Proteomic technologies are used with increasing frequency in the renal community. In this review, we highlight the use in renal research of a number of available techniques including two-dimensional gel electrophoresis, liquid chromatography/mass spectrometry, surface-enhanced laser desorption/ionization, capillary electrophoresis/mass spectrometry, and antibody and tissue arrays. These techniques have been used to identify proteins or changes in proteins specific to regions of the kidney or associated with renal diseases or toxicity. They have also been used to examine protein expression changes and posttranslational modifications of proteins during signaling. A number of studies have used proteomic methodologies to look for diagnostic biomarkers in body fluids. The rapid rate of development of the technologies along with the combination of classic physiological and biochemical techniques with proteomics will enable new discoveries.  (+info)

Evidence that postprandial reduction of renal calcium reabsorption mediates hypercalciuria of patients with calcium nephrolithiasis. (5/120)

Idiopathic hypercalciuria (IH) is common among calcium stone formers (IHSF). The increased urinary calcium arises from increased intestinal absorption of calcium, but it is unclear whether increased filtered load or decreased renal tubular reabsorption of calcium is the main mechanism for the increased renal excretion. To explore this question, 10 IHSF and 7 normal subjects (N) were studied for 1 day. Urine and blood samples were collected at 30- to 60-min intervals while subjects were fasting and after they ate three meals providing known amounts of calcium, phosphorus, sodium, protein, and calories. Fasting and fed, ultrafiltrable calcium levels, and filtered load of calcium did not differ between N and IHSF. Urine calcium rose with meals, and fractional reabsorption fell in all subjects, but the change was significantly higher in IHSF. The changes in calcium excretion were independent of sodium excretion. Serum parathyroid hormone levels did not differ between N and IHSF, and they could not account for the greater fall in calcium reabsorption in IHSF. Serum magnesium and phosphorus levels in IHSF were below N throughout the day, and tubule phosphate reabsorption was lower in IHSF than N after meals. The primary mechanism by which kidneys ferry absorbed calcium into the urine after meals is via reduced tubule calcium reabsorption, and IHSF differ from N in the magnitude of the response. Parathyroid hormone is not likely to be a sufficient explanation for this difference.  (+info)

Hypocitraturia despite potassium citrate tablet supplementation. (6/120)

Citrate supplementation is widely used in the prevention of recurrent nephrolithiasis with hypocitraturia. Potassium citrate is the most commonly used citrate agent for this indication. In patients with chronic diarrheal syndromes, the absorption of potassium citrate can be affected. We describe a patient who presented with recurrent nephrolithiasis and chronic diarrhea and was found to have severe hypocitraturia despite citrate supplementation with potassium citrate tablets, likely due to inadequate gastrointestinal absorption of citrate from the slow-release wax-matrix tablets.  (+info)

Oxalate intake and the risk for nephrolithiasis. (7/120)

Most kidney stones consist of calcium oxalate, and higher urinary oxalate increases the risk for calcium oxalate nephrolithiasis. However, the relation between dietary oxalate and stone risk is unclear. This study prospectively examined the relation between oxalate intake and incident nephrolithiasis in the Health Professionals Follow-up Study (n = 45,985 men), the Nurses' Health Study I (n = 92,872 older women), and the Nurses' Health Study II (n = 101,824 younger women). Food frequency questionnaires were used to assess oxalate intake every 4 yr. Cox proportional hazards regression was used to adjust for age, body mass index, thiazide use, and dietary factors. A total of 4605 incident kidney stones were documented over a combined 44 yr of follow-up. Mean oxalate intakes were 214 mg/d in men, 185 mg/d in older women, and 183 mg/d in younger women and were similar in stone formers and non-stone formers. Spinach accounted for >40% of oxalate intake. For participants in the highest compared with lowest quintile of dietary oxalate, the relative risks for stones were 1.22 (95% confidence interval [CI] 1.03 to 1.45; P = 0.01 for trend) for men and 1.21 (95% CI 1.01 to 1.44; P = 0.05 for trend) for older women. Risk was higher in men with lower dietary calcium (P = 0.08 for interaction). The relative risks for participants who ate eight or more servings of spinach per month compared with fewer than 1 serving per month were 1.30 (95% CI 1.08 to 1.58) for men and 1.34 (95% CI 1.10 to 1.64) for older women. Oxalate intake and spinach were not associated with risk in younger women. These data do not implicate dietary oxalate as a major risk factor for nephrolithiasis.  (+info)

Incomplete distal renal tubular acidosis affects growth in children. (8/120)

BACKGROUND: Incomplete distal renal tubular acidosis (idRTA) is recognized as an underlying aetiology in recurrent nephrolithiasis. Until the recently reported high prevalence of idRTA in adults with osteoporosis, the effect of idRTA on skeletal parameters was not known. We hypothesize that idRTA has a potential to affect height in the paediatric population. METHODS: In a cross-sectional study, the children with posterior urethral valves (PUV), with normal estimated glomerular filtration rates, were evaluated for idRTA and complete dRTA. The idRTA evaluation was done by short ammonium chloride acidification test. The height standard deviation scores (SDS) in the idRTA group were compared with PUV children without dRTA, with complete dRTA, and to age and gender matched controls with no renal issue (n = 50). RESULTS: The idRTA group (n = 17) manifested a significantly lower mean height SDS (-1.94 +/- 0.41 vs -0.46 +/- 0.28; P < 0.001) and a higher short stature prevalence (height SDS below 2) (18% vs 0; P = 0.06) as compared with those without dRTA (n = 23). The matched controls showed a significantly higher height SDS as compared with the idRTA group (-0.39 +/- 0.25 vs -1.94 +/- 0.41; P < 0.001). As compared with the complete dRTA group (n = 9), the children with idRTA did have significantly higher height SDS (-1.94 +/- 0.41 vs -5.31 +/- 1.95; P = 0.002), and a lower short stature prevalence (18% vs 78%; P = 0.001). On multivariate analysis, dRTA was significantly associated with the height SDS (= -0.88; P < 0.001). CONCLUSIONS: Incomplete dRTA affects height in children. This observation needs validation in longitudinal studies.  (+info)

FRIDAY, Jan. 15, 2016 (HealthDay News) - A growing number of teens, women, and blacks are being diagnosed with nephrolithiasis, according to findings published online Jan. 14 in the Clinical Journal of the American Society of Nephrology.. The researchers analyzed data from South Carolina from 1997 to 2012, and found that the annual incidence of nephrolithiasis among children and adults rose 16 percent during that time. The largest increases were among teens (4.7 percent a year), females (3 percent a year), and blacks (2.9 percent a year). During the study period, the risk of nephrolithiasis doubled among children, and there was a 45 percent increase in the lifetime risk for women.. Teen girls had the highest rate of increase in nephrolithiasis, and they were more common among females aged 10 to 24 than among males in the same age group. After age 25, nephrolithiasis was more common in men, the study authors said. Nephrolithiasis incidence rose 15 percent more in blacks than in whites during each ...
Calcium oxalate nephrolithiasis is a relatively common disease. The prevalence in the general population may range from 10 to 12 percent, and 0.4 to 1 percent of new cases are reported every year according to different series. Without specific pharmacological therapy, the recurrence rate in patient with established diagnosis of nephrolithiasis is extremely high and may range from 15 to 20 percent per year, with a cumulative incidence at five years ranging from 27 to 50 percent.Although genetic factors play an important role in the development of nephrolithiasis, environmental factors such as diet also appear to affect stone formation. Potassium citrate is also effective in preventing stone recurrence in patients with calcium oxalate nephrolithiasis. Low tolerability, however, may remarkably limit the use of these medication. Citrus fruits are a natural rich source of citrate and diet supplementation with juice of citrus fruits may represent a valuable alternative option to supply citrate without ...
TY - JOUR. T1 - A polymorphism of the ORAI1 gene is associated with the risk and recurrence of calcium nephrolithiasis. AU - Chou, Yii-Her. AU - Juo, Suh-Hang Hank. AU - Chiu, Yi-Ching. AU - Liu, Mu-En. AU - Chen, Wei-Chiao. AU - Chang, Chen-Chia. AU - Chang, Wei Pin. AU - Chang, Jan-Gowth. AU - Chang, Wei-Chiao. PY - 2011/5. Y1 - 2011/5. N2 - Purpose: Store-operated calcium entry has been considered an important factor to regulate inflammatory reactions in nonexcitable cells. However, the effects of genetic polymorphisms of ORAI1, a main component of store-operated calcium channels, on nephrolithiasis and stone recurrence remain unclear. We investigated the association between calcium containing nephrolithiasis and genetic variants of ORAI1 gene in Taiwanese patients. Materials and Methods: A case-control study was performed in 136 patients with nephrolithiasis and 500 controls. Five tagging single nucleotide polymorphisms of ORAI1 were selected for genotyping. ORAI1 genotypes were determined ...
INTRODUCTION: The incidence of pediatric nephrolithiasis (kidney stones) has been increasing over the past several years. While environmental factors, such as poor fluid intake, high-salt diet, and obesity, can play a role, underlying metabolic factors account for at least one-third of cases of nephrolithiasis. Nephrolithiasis and related disorders, such as nephrocalcinosis and hypercalciuria, can lead to long-term kidney problems, including renal scarring, acute and chronic kidney disease, decreased renal function, or end-stage renal disease. The best treatment is prevention and is best guided by knowing the underlying cause. The majority of kidney stones are primarily comprised of calcium, and abnormal calcium metabolism and regulation can lead to nephrolithiasis, nephrocalcinosis, and hypercalciuria. Vitamin D is an important factor in calcium regulation in the body. The physiologically active form of vitamin D is 1α,25-dihydroxyvitamin D (1,25(OH)2D), which increases serum calcium by ...
Burgess, KL, Gettman, MT, Rangel, LJ, Krambeck, AE. Diagnosis of urolithiasis and rate of spontaneous passage during pregnancy. J Urol. vol. 186. 2011. pp. 2280-4. Butler, EL, Cox, SM, Eberts, EG, Cunningham, FG. Symptomatic nephrolithiasis complicating pregnancy. Obstet Gynecol. vol. 96. 2000. pp. 753-6. Maikranz, P, Coe, FL, Parks, J, Lindheimer, MD. Nephrolithiasis in pregnancy. Am J Kidney Dis. vol. 9. 1987. pp. 354-8. Riley, JM, Dudley, AG, Semins, MJ. Nephrolithiasis and Pregnancy: Has the Incidence Been Rising?. J Endourol. 2013 Dec 17. Rosenberg, E, Sergienko, R, Abu-Ghanem, S, Wiznitzer, A, Romanowsky, I. Nephrolithiasis during pregnancy: characteristics, complications, and pregnancy outcome. World J Urol. vol. 29. 2011. pp. 743-7. Ross, AE, Handa, S, Lingeman, JE, Matlaga, BR. Kidney stones during pregnancy: an investigation into stone composition. Urol Res. vol. 36. 2008. pp. 99-102. Srirangam, SJ, Hickerton, B, Van Cleynenbreugel, B. Management of urinary calculi in ...
Nephrolithiasis is a common condition affecting about 5 to 10% of individuals worldwide. It is multi factorial caused by both genetic and non-genetic factors including dietary and environmental factors. Mutations in the genes currently linked to nephrolithiasis are estimated to be responsible for about 15% of kidney stone cases.. The nephrolithiasis and related disorders NGS panel consists of thirty-one genes: ADCY10, AGXT, AP2S1, APRT, ATP6V0A4, ATP6V1B1, CA2, CASR, CLCN5, CLDN16, CLDN19, CYP24A1, FAM20A, GNA11, GRHPR, HNF4A, HOGA1, HPRT1, KCNJ1, OCRL, SLC2A9, SLC3A1, SLC4A1, SLC7A9, SLC9A3R1, SLC12A1, SLC22A12, SLC26A1, SLC34A1, SLC34A3 and XDH.. Copy number variation (CNV) analysis of the nephrolithiasis and related disorders genes is also offered as a panel. Additionally, CTGT offers a comprehensive test (both NGS and CNV panels) for these genes. Panel genes are also offered as individual sequencing and deletion/duplication tests unless otherwise indicated.. ...
FLOMAX NEPHROLITHIASIS PDF - Kidney Stones |; Tamsulosin Ineffective for Small Ureteral Stones In the double-blind STONE (Study of Tamsulosin for Urolithiasis in the. Nephrolithiasis
Nephrolithiasis is considered a systemic disease. A link has been established between nephrolithiasis, cardiovascular disease (CVD), the metabolic syndrome and atherosclerosis.
The morbidity of nephrolithiasis is 2-3 times higher in males than in females, suggesting that androgen plays a key role in nephrolithiasis. The death of renal tubular epithelial cells (TECs) is an important pathophysiological process contributing to the development of nephrolithiasis. Therefore, the aim of this study is to investigate whether androgen directly induces TECs apoptosis and necrosis and its underlying mechanisms in kidney stone formation. We compared serum testosterone level between male and female healthy volunteers and kidney stone patients. The in vivo nephrolithiasis model was established using glyoxylic acid, and calcium deposits were detected by van Kossa staining. In the in vitro study using mouse TECs (TCMK-1 cells) and human TECs (HK-2 cells), apoptosis, necrosis, and the expression of BH3-only protein Bcl-2-like 19 kDa-interacting protein 3 (BNIP3) were examined incubated with different doses of testosterone using flow cytometry. Levels of apoptosis-related proteins transfected
BACKGROUND AND PURPOSE: Hypocitraturia, an important risk factor for calcium oxalate nephrolithiasis, is the result of numerous factors. We studied citrate excretion by patients with and without stones consuming normal and controlled formula diets. S
The study will use a combination of cell culture, animal, and human studies employing some of the latest technologies in magnetic resonance spectroscopy and single-photon emission computed tomography, combined with classical physiology, biochemistry, and molecular biology to test four interrelated hypotheses. There is increased uptake of free fatty acids into the kidney as a result of higher circulating levels as well as preferential transport by the proximal tubule as part of a conditioning effect. The increased provision of free fatty acid supplies metabolic substrate for ATP generation hence reducing the consumption of other substrates such as glutamine, which is the principal source of ammoniagenesis by the proximal tubule. This substrate competition, or metabolic switch, can lower the formation of the major urinary buffer ammonia, even in the absence of injury to the proximal tubule. With sustained lipid loading of the proximal tubule that exceeds its oxidative capacity, lipid storage is ...
ASKEP NEPHROLITHIASIS PDF - Siswoyo. Dep. KMB-Kritis PSIK UNEJ. Urolithiasis, kidney stones, renal stones, and renal calculi are used interchangeably to refer to the accretion of
A recent study published in AJKD by Dhondup et al provides a number of helpful insights into the progression of kidney disease in patients with nephrolithiasis. Although the economic burden of kidney stones to the healthcare system has been well established for decades, the emerging evidence to support a link to diminished kidney function, end-stage…
A rare condition in itself, acquired hemophilia A, seldom presents as isolated gross hematuria. It is a serious condition with a high mortality rate and thus clinical suspicion followed by prompt diagnosis is imperative (1). In fact, only 8 cases of such presentation of this condition have been reported thus far in the literature. Of these, none describe the initial presentation of hematuria with the inciting event of a kidney stone. We present a case of a 67-year-old man with signs and symptoms of nephrolithiasis accompanied by profuse hematuria, who was subsequently found to have developed expression of factor VIII inhibitor leading to acquired hemophilia A ...
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Background: Great ambient temps are a risk element for nephrolithiasis, but the precise relationship between heat and kidney stone demonstration is unknown. for any daily mean heat of 30C versus 10C was 1.38 in Atlanta (95% CI: 1.07, 1.79), 1.37 in Chicago (95% CI: 1.07, 1.76), 1.36 in Dallas (95% CI: 1.10, 1.69), 1.11 in Los Angeles (95% CI: 0.73, 1.68), and 1.47 in Philadelphia (95% CI: 1.00, 2.17). Kidney stone presentations also were positively associated with temps < 2C in Atlanta, and < 10C in Chicago and Philadelphia. In four towns, the strongest association between kidney stone presentation and a daily mean heat of 30C versus 10C was estimated for lags of 3 days. Conclusions: In general, kidney stone presentations improved with higher daily mean temps, with the strongest associations estimated for lags of only a few days. These findings support an adverse aftereffect of high temperatures in nephrolithiasis additional. Citation: Tasian GE, Pulido JE, Gasparrini A, Saigal CS, Horton BP, ...
American Urological Association website. Medical management of kidney stones (2019). www.auanet.org/guidelines/kidney-stones-medical-mangement-guideline. Accessed Feb 13, 2020. American Urological Association website. Surgical management of stones: AUA/Endourology Society guideline (2016) www.auanet.org/guidelines/kidney-stones-surgical-management-guideline. Accessed Feb 13, 2020. Bushinsky DA. Nephrolithiasis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 117. Fink HA, Wilt TJ, Eidman KE, et al. Recurrent nephrolithiasis in adults: comparative effectiveness of preventive medical strategies. Rockville, MD. Agency for Healthcare Research and Quality (US) 2012;Report No.:12-EHC049-EF. PMID: 22896859 pubmed.ncbi.nlm.nih.gov/22896859/. Miller NL, Borofsky MS. Evaluation and medical management of urinary lithiasis. In: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; ...
Nephrolithiasis is the formation of renal stones, which is a common problem in primary care practice. Patients with kidney stones often present with renal colic, hematuria or vague abdominal pain, acute abdominal or flank pain, nausea, difficulty urinating, penile pain or testicular pain. Of all patients, about 80% forms Ca2+-containing stones and the cause is generally unknown. The successful cloning by our group of the new calcium channel TRPV5 offers a realistic approach to study the physiological, functional and regulatory aspects of the renal calcium balance, which contributes to nephrolithiasis. Knowledge of TRPV5 functioning will, in particular, provide a molecular basis for achieving a better understanding of calcium related disorders in which (re)absorption processes are disturbed. TRPV5 is uniquely regulated by the anti-aging hormone klotho which hydrolysis the N-glycan to stabilize the channel in the membrane. Alterations in calcium (re)absorption are present in many physiological and ...
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes several isoforms which have different expression patterns and functions. Mutation in this gene is associated with uric acid nephrolithiasis (UAN). Alternatively spliced variants, encoding distinct proteins, have been identified. [provided by RefSeq, May 2010 ...
These reactions may be indicated. A focus on direction and evaluation of difficulty in hospital inpatients. The elimination rate constant is needed to provide patient specific, also occur. The CKD-EPI study equation was compared to as sulfur mustard, education levels, proteinuria, social history, targeted therapy remains elusive. SJS/TEN: are most commonly seen in palliative care patients. Severe heart failure decreases cardiac output and sweet oil (25%). The procedure for the quality of liver abscesses over 4 to the 5-hour sampling was 17% higher. The report stated that are rare, also referred to identifying the usual therapeutic dose of bleeding as little as animal and uric acid nephrolithiasis. The most current RDT involves genomic testing methodologies, celiac disease was considered a community such as travel associated venous thromboembolism (TAVTE), and thrombocytopenia in patients with increased medical costs and the lysosome is damaged, including supportive care and bioavailability in ...
The OBrien Urology Research Center investigates what we believe are critical unanswered questions in nephrolithiasis research. These questions are addressed through an integrated approach that includes translational imaging research to develop a noninvasive, in vivo diagnostic test to characterize kidney mineralization; basic science investigation of the molecular mechanisms oxalate transport; definition of the key urinary factors (electrolyte and proteomic) that drive formation of nascent renal stones; and epidemiologic and biochemical investigation of the relationship between nephrolithiasis and CKD in order to allow early identification of those at risk.. Read More. ...
Some stones, such as those composed of uric acid or cystine, are pH-dependent, meaning that they can form only in acidic conditions. Calcium phosphate and struvite only form when the urine pH is alkal... more
In this agreeable volume the 10 chapters jostle each other, and produce silent cadences that may be as valuable as the mass of information they contain. Taken one by one, the contributions are standard professional fare, of good to excellent quality. Coburn, Massry, and colleagues, in two chapters, review intestinal absorption and renal handling of calcium, magnesium and phosphorus in chronic renal insufficiency. They are expert.. The editor provides a useful compendium of mineral disturbances in uremia. That lacks the laconic terseness of the other essays, perhaps because most of it reviews work outside of his own personal research area; ...
The surgical, metabolic and anatomical studies we performed during the last funding period have characterized the histopathological and mineral composition in s...
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This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each societys website. Some
Build: Wed Jun 21 18:33:50 EDT 2017 (commit: 4a3b2dc). National Center for Advancing Translational Sciences (NCATS), 6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-435-0888. ...
Nephrolithiasis is a highly prevalent disease worldwide with rates ranging from 7 to 13% in North America, 5-9% in Europe, and 1-5% in Asia. Due to high rates of new and recurrent stones, management of stones is expensive and the disease has a high level of acute and chronic morbidity.
DESCRIPTION (provided by applicant): Nephrolithiasis (NL) affects up to 10% of the population producing significant pain and suffering, as well as great economic costs (up to $5.3 billion per year in the United States). Treatment strategies are imperfect and have not improved substantially over the last 30 years, in part because the key pathogenic steps remain poorly defined. Therefore, we have assembled a multidisciplinary team to define genetic risk factors for NL. A key and unique resource of our application is the Rochester, MN cohort of the Genetic Epidemiology Network of Arteriopathy (GENOA), which has conducted genome-wide linkage and association studies to identify genes influencing blood pressure and end-organ complications of hypertension (HTN). Members of the well-characterized GENOA cohort will be phenotyped for kidney stone risk via 24-hour urine measurements of lithogenic factors including calcium, oxalate, citrate, and uric acid excretion, as well as overall crystallization ...
Kidney stone is basically stone or hard crystalline material formed due to the accumulation of salt in the kidney or urinary tract. Stones that is formed in the kidney is known as Nephrolithiasis. Stones that are formed anywhere in the Urinary tract is known as Urolithiasis. Dr. Padeep Rao is one of the Best Urologist in Mumbai who is famous for his Kidney Stone Removal Treatments in Mumbai. ...
The formation of stones in the urinary tract stems from a wide range of underlying disorders. That clinicians look for the underlying causes for nephrolithiasis is imperative to direct management. There are many advances in genetics, pathophysiology, diagnostic imaging, medical treatment, medical pr …
1 Answer - Posted in: nephrolithiasis, pain, kidney - Answer: You can do that. It might help. Flomax can help too, it relaxes the...
The new Profile feature might help researchers develop new hypotheses regarding gene function based on the functions of genes with similar expression profiles. To create an example, I picked more or less at random from past posts. I chose the gene Prestin, which is related to kidney stones or nephrolithiasis (view the original post here). A single gene match comes up in this case, CG42365, a gene with unknown function that does not appear to have been evolutionarily conserved. I have searched with a handful of gene names. For most genes I searched, the results came back with between ten and a hundred or so genes with similar profiles to that of my entry gene. If you are trying to understand a human disease gene ortholog, searching at FlyAtlas Profiles might be one of many searches that could help in study design and interpretation ...
Fatty acid binding protein 4 is an essential molecule for the development of kidney stones: A new understanding of why obesity and nephrolithiasis go hand in ...
to the editor: Occult lead poisoning is a difficult diagnosis to make in a primary care setting because the symptoms of plumbism are non-specific. We would like to report a case in which unsuspected lead toxicity resulted in a delayed diagnosis and inconclusive hospital work-up.. A healthy 57-year-old man developed abdominal pain and lower back pain over the course of several days. He had no significant medical history, took no medications, and had no known allergies. He denied having any antecedent trauma and reported no other symptoms. His vital signs were normal and physical examination was unremarkable. Rapid office tests revealed a hemoglobin level of 9.7 g per dL (97 g per L) and blood on urine dipstick. The patient was admitted to the hospital for nephrolithiasis work-up and treatment. Despite an extensive three-day hospital evaluation, work-up was inconclusive.. At follow-up after discharge, the patient continued to have the same symptoms; he then revealed that he was a welder exposed to ...
Hematology case studies: platelets. each month a case a series of questions can be emailed to interested individuals 4- 6 weeks in advance of publication. aacc uses cookies to ensure the best website experience. continuing without changing cookie settings assumes you consent to our use of cookies on this mlt case studies device. chemistry mlt case study: unexplained metabolic acidosis case workup a 24- year- mlt case studies old female at 34 weeks of gestation was transferred from an outside hospital with history of nephrolithiasis right side pyelonephritis for which she underwent stent placement 2 weeks ago. case studies each case study presents a case laboratory diagnosis, treatment, , discussing its pathogenesis, clinical , often rare in nature prognosis. this program is intended for individuals who wish to maintain laboratory certification for those interested in staying current in the ever- changing field of laboratory medicine. case studies in clinical laboratory science. unique in its ...
A disorder affecting the small intestine. It is caused by the stasis of food and subsequent overgrowth of bacteria in a portion of the small intestine that is unintentionally bypassed as a complication of abdominal surgery or as a sequela of gastrointestinal disorders which impede effective motility. Clinical signs include bloating, abdominal pain, diarrhea and weight loss. If untreated, the clinical course progresses to malabsorption of fats, vitamin B12 and calcium, the latter which predisposes to nephrolithiasis and osteoporosis. [from NCI] ...
1. Among those presenting with symptomatic nephrolithiasis, patients electing for trial of passage with medical expulsion therapy were more likely to receive a
New research shows that lemonade is an effective -- and delicious -- way for kidney-stone-prone people to slow the development of new stones.
:confused: ok heres the situation a pt arrives in the ED at 0300 labs are drawn but pt is in respriatory failure and intubated. No history is known. She is sent to the unit at 0700. She recieve a
Betanidine: Search drug information, interaction, images & medical diagnosis. The most comprehensive database of medicines available in China, Hong Kong, T...
WEDNESDAY, March 3, 2021 (HealthDay News) - Almost one-quarter of patients with kidney stone disease have a prevalent diagnosis of osteoporosis or fracture, and screening after diagnosis identifies additional patients with osteoporosis, according to a study published online March 3 in the Journal of Bone and Mineral Research.. Calyani Ganesan, M.D., of Stanford University in California, and colleagues conducted a retrospective cohort study to examine the prevalence of osteoporosis and fractures and rate of bone mineral density screening by dual-energy X-ray absorptiometry (DXA) using data from the Veterans Health Administration. A total of 531,431 patients were identified with kidney stone disease between 2007 and 2015.. The researchers found that 23.6 percent of patients with kidney stone disease had a prevalent diagnosis of osteoporosis or fracture. Of those with no previous history of osteoporosis or bone mineral density assessment before diagnosis, 9.1 percent of patients were screened with ...
BACKGROUND--Renal calculi have been reported to occur in about 10% of patients with chronic sarcoidosis, but nephrolithiasis as a presentation of this disease has not been studied. METHODS--The charts of 618 patients with histologically proven sarcoidosis, seen in the period October 1978-1992, were reviewed in order to identify nephrolithiasis at presentation. RESULTS--Seventeen patients had renal calculi which preceded other manifestations of sarcoidosis. In six the occurrence of calculi suggested the diagnosis. Another eight patients had a previous history of recurrent colic with calculi. The time intervals between the first calculus and the appearance of other manifestations of sarcoidosis ranged from one to 25 years, but it was over four years in only two cases and all had at least one calculus in the year before the diagnosis was made. In the other three patients appearance of the calculus was distant in time and was probably unrelated to their sarcoidosis. In most cases the sarcoidosis was ...
15 04 2020Successful management of uric acid nephrolithiasis with potassium citrate Pak CY Sakhaee K Fuller C Eighteen patients with uric acid nephrolithiasis (six with uric acid stones alone and 12 with both uric acid and calcium stones) underwent long-term treatment (1 to 5 33 years mean of 2 78 years) with potassium citrate (30 to 80 mEq/day usually 60 mEq/day) Get More ...
Discover the latest Kidney stone disease related news stories from Chester County and Pennsylvania. MyChesCo provides local coverage and analysis of Kidney stone disease related news.
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis.
Introduction: The role of magnesium supplement to prevent primary and/or secondary kidney stones has not been fully determined. The aim of this study is to evaluate the effects of magnesium supplement in modifying urinary risk factors of recurrent kidney stones.Method: We searched MEDLINE, Scopus, and Google Scholar databases on December 7, 2014 and reference lists of systematic reviews and randomized, controlled trials. Among the initial 282 articles found by our search strategy and hand searching, we found eight English-language studies were eligible for our study.Result: Magnesium supplementation could be beneficial in nephrolithiasis prevention through increasing urinary magnesium, citrate, and calcium while declining urinary oxalate. In pediatric patients, the results were more prominent and could decline urinary oxalate up to 90% of the baseline.Conclusions: Magnesium supplementation could be beneficial, especially with potassium-citrate combination. However, due to the low number of well-designed
Rowatinex For the Treatment & Prevention of Ur-Olithiasis, Nephrolithiasis & Other Urinary Tract Disorders Composition : Each Capsule contains; Alpha Pinene 24.8 mg Beta Pinene 6.2 mg Camphene 15
Nephrolithiasis is a common diagnosis in the ED. Evidence over the past 2 decades suggests an increasing prevalence of kidney stones, citing an increase from 3.8% between 1976 and 1980 to 8.4% between 2007 and 2010.1 This increase was seen particularly in women, with an overall male-to-female ratio decreasing from 3:1 to less than 2:1 over the past 25 years.2. A large number of factors may contribute to kidney stone formation. Known risk factors include high urine calcium, high urine oxalate, low urine citrate, and low urine volume. Dietary factors such as low intake of fluid, calcium, potassium, and phytate or high intake of oxalate, sodium, sucrose, fructose, and animal protein also predispose patients to stones.3 Additionally, a number of medical conditions increase the risk of nephrolithiasis, chiefly primary hyperparathyroidism, obesity, gout, diabetes, and medullary sponge kidney.. Nephrolithiasis can be asymptomatic. Roughly 70% of asymptomatic cases remain asymptomatic after 31 months.4 ...
Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis ...
Lemonade is an effective way for kidney-stone-prone people to slow the development of new stones, according to a study conducted at the University of Wisconsin. Researchers found lemon juice increases the amount of citrate in the urine to levels known to inhibit kidney stones. While it doesnt work as well as potassium citrate usually prescribed by doctors, lemonade therapy provides an attractive alternative for patients who want to avoid yet another medication. ...
We will send you your Kidney Stone Analysis stone test sample collection kit which contains everything you need to take your stone sample in the comfort of your own home. Your doctor will base your surgical treatment on your present physical condition as well as the size of your kidney stones. Though there are drugs to prevent the formation of stone, no specific drug is there to treat a stone. Moderate drinking in truth has positive effects on ones health.Certain alcoholic drinks contain antioxidants enabling harmful toxins to be flushed out of the system effectively. They usually pass on their own, but can cause severe pain in the process, though larger stones occasionally require do kidney stones cause diarrhea list
Urolithiasis, commonly referred to as kidney stones, is a painful condition that affects 1 out of 20 women. Fortunately, kidney stone disease can be prevented using modern diagnostic testing and treatment methods. If you have a history of kidney stones, you may be asked to drink 6 - 8 glasses of water per day to produce enough urine. The urologists at SUS employ the latest treatments and technologies to diagnose and prevent kidney stone disease. Depending on the type of stone, we will prescribe appropriate medications or recommend diet changes to prevent stone recurrence.. ...
PURPOSE: The treatment of a first-time renal stone episode consists of acute management followed by medical efforts to prevent stone recurrence. Though nephrolithiasis is roughly 50% heritable, the presence of a family history usually does not affect treatment, as most stone disease is regarded as polygenic, i.e. not attributable to a single gene. Recently, new evidence has suggested that single mutations could be responsible for a larger proportion of renal stones than expected. This intriguing possibility holds the potential to change the management paradigm in stone prevention from metabolically-directed therapy to more specific approaches informed by genetic screening and testing. This review aims to synthesize new findings concerning monogenic kidney stone disease and provide a concise and clinically useful reference of monogenic causes. It is expected that increased awareness of these etiologies will eventually lead to increased utilization of genetic testing in recurrent stone formers and ...
Uricosuric agents (eg, allopurinol) Alkalinizing agents (eg, potassium citrate, sodium bicarbonate): For uric acid and cysteine calculi Thiazide diuretics: Help treat hypercalcicuria
Men and women with gout are at 60% greater risk for nephrolithiasis than adults without gout, according to a study looking at not only the chronic kidney conditions incidence but also potential risk factors for first-time nephrolithiasis in people with and without gout.
Obese patients with type 2 diabetes frequently have acidic urine due to hyperinsulinemia, inducing a decrease in ammonia production in the proximal tubule and sodium clearance. The resulting lower urine pH can cause uric acid to come out of solution and crystallize (2). Although most calculi in obese participants with type 2 diabetes are composed of calcium oxylate, the proportion of uric acid stones is higher than in control participants (35.8% vs. 11.3%) (3). Normal uric acid excretion is less than 800 mg/d, but uric acid can crystallize at levels as low as 200 mg/day in the presence of acidic urine. In this situation, the most effective therapies to prevent stone formation are allopurinol to reduce uricosuria and citrates to neutralize the acidic urine ...
Approximately 10 million adults in the United States have experienced the passage of a kidney stone, and up to 5 million have been diagnosed with gout by a physician. Previous reports have suggested that gout increases the risk for the development of kidney stones, but there are no prospective data. …
Men are affected 2-3 times more than women. It is more common in whites, followed by hispanics, asians, and african-americans. It is uncommon before age 20 but peaks in the fourth to sixth decades of life. It has a higher prevalence in hot, arid, or dry climates (mountains, desert, or tropical areas). However, genetic factors and diet may influence this disease. Heat exposure and dehydration are occupational risk factors for kidney stone disease. Also overweight and high body mass index are directed related to kidney stone disease. Despite this risk factors, the most important risk factor is dehydration, so a high fluid intake can prevent urolithiasis.. ...
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The high morbidity rate associated with kidney stone disease, which is a silent killer, is one of the main concerns in healthcare systems all over the world. Advanced data mining techniques such as classification can help in the early prediction of this disease and reduce its incidence and associated costs. The objective of the present study is to derive a model for the early detection of the type of kidney stone and the most influential parameters with the aim of providing a decision-support system. Information was collected from 936 patients with nephrolithiasis at the kidney center of the Razi Hospital in Rasht from 2012 through 2016 ...
Of emboli within the limited number of patients with suspected pe establishes the cost cialis prescription does much presence of asso- ciated symptoms. It has been shown to increase the measured valve area of previous symptoms plus mydriasis, piloerection, vitamin replenishment. Lactic acidosis for reasons that its intrinsic renal failure. Shock occurs in icu patients prior to elective procedures. Radiographics 173. Between fourth and fifth fingers. Probiotics are widely (usually suggested by a decline. Osteomala- b. Deficient calcium intake only benefits 6. Hyperoxaluric hyperoxaluric calcium nephrolithiasis the small joints of the american diabetes association and bone pain, mity, intractable pain, and thromboses, vasculitis with major disability, plasmapheresis or phosphatase, and husain z et al. Signs of cutaneous urinary diversion without pelvic lymph node mass more than 8 meq/l una+ > 19 meq/l suggests a functional level.117 for the development of rcc. Patients with low or high vitamin ...
One in every 20 people develop kidney stones at some point in their life. A kidney stone is a hard, crystalline mineral material formed within the kidney or urinary tract. Nephrolithiasis is the medical term for kidney stones. On Doctors On Call we find out from Dr Ruchi Samdani, a senior Nephrologist at Jaslok Hospital in Mumbai, about the symptoms and prevention of kidney stones.|br||/br||b|(Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.)|/b|
In medical terms, kidney stones called Nephrolithiasis or renal calculi. Kidney stones are a condition with one or more stones in the pelvis or calyces of the kidney or in the ureter channel. The formation of kidney stones can occur in any part of the urinary tract, but usually formed in two parts most of the kidney, that is in tubs kidney (renal pelvis) and renal Calix. Stones can be formed from calcium, phosphate, or a combination of uric acid is usually dissolved in the urine ...
Whenever we go out to eat, and the waitress takes our drink order, I ALWAYS ask for water with obscene amounts of lemon. Ive noticed there is a direct correlation between the amount of lemon a waitress brings me and the size of a tip I leave her. I LOVE LEMON! And in my water, the more lemon the better. I realize not everyone would appreciate the tartness, but with a meal, or for quenching my thirst, nothing is finer!. This is not true when I garden, however. I think the hot weather and physical exertion makes me yearn for something sweeter. While gardening, I want lemonade with PLENTY of sugar. And since I need to continually replenish liquids on hot days, I usually take a quarter Mason jar full of lemonade out to the garden with me. Besides holding lots of lemonade, it also has a handy, dandy lid in case you knock it over or to prevent bugs from partaking of your beverage. Below is my recipe for yummy and refreshing lemonade. Definitely have the kids make their own!. Garden Lemonade. 1 ...
A kidney stone, also known as a renal calculus is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. Urinary stones are typically classified by their location in the kidney (nephrolithiasis), ureter (ureterolithiasis), or bladder (cystolithiasis), or by their chemical composition (calcium-containing, struvite, uric acid, or other compounds). Kidney stones typically leave the body by passage in the urine stream, and many stones are formed and passed without causing symptoms. If stones grow to sufficient size they can cause obstruction of the ureter. Ureteral obstruction causes postrenal azotemia and hydronephrosis (distension and dilation of the renal pelvis and calyces), as well as spasm of the ureter. - Stock Image C017/5014
The GW Medical Faculty Associates is the largest independent physician group in the DC area with more than 750 providers and 51 clinical specialties.
How to make diet lemonade. . Master Cleanse Diet Lemonade Recipe. 44 Me gusta. tmash.press Lemonade Recipe Master Cleanse Diet. Beyonce Knowles lost about 20 pounds with the Master Cleanse lemonade diet for her role in the movie Dreamgirls. To know more about this lemonade recipe..
Learning Resources, a manufacturer of innovative hands-on educational products and toys, is hosting a good old fashioned Lemonade Stand as part of Alexs Lemonade Stand Foundations national fundraiser, Lemonade Days. Proceeds will benefit Alexs Lemonade Stand Foundation, a nonprofit dedicated...
Kidney stones (renal lithiasis, nephrolithiasis) are hard deposits made of minerals and salts that form inside your kidneys. Kidney stones have many causes and can affect any part of your urinary tract - from your kidneys to your bladder. Often, stones form when the urine becomes concentrated, allowing minerals to crys
Dr. Childs responded: No. Lemon juice and lemonade are recommended for prevention of kidney stones. Lemonade increases urinary citrate levels. Citrate helps block the formation of certain kinds of |a href=/topics/calcium track_data={
Join UCLA urologist Kymora Scotland, MD, PhD, for an overview on kidney stones. Kidney stones affect approximately 10% of the population in the U.S. Moreover, up to 50% of patients with kidney stone disease will have a recurrence. Dr. Scotland will discuss how and why stones form and what we can do to manage them.
Rising temperatures and increased dehydration linked to global warming will boost kidney stone rates in the United States and around the world, new research suggests. In the United States in particular, hotter weather will lead to a dramatic rise in kidney stone disease among residents of southern states -- the so-called kidney-stone belt. This will result in an increase of
Kidney stones are one of the most common health issues nowadays and people need to find the cure for it, or to find something to prevent. In this post we are going to present you the remedies which will help you to eliminate the stones. The conditions are called nephrolithiasis, which are composed of had,…
nyresten, urolithiasis, nephrolithiasis, kidney stone, stone analysis, calcium oxalate, uric acid, urinsyre, sten, Kim Hovgaard Andreassen, urolithiasis guide, stenanalyse, årsager til nyresten, cystinuri ...
Autor: Tanaka, Karo et al.; Genre: Zeitschriftenartikel; Im Druck veröffentlicht: 1999; Open Access; Titel: Characterization of novel promoter and enhancer elements of the mouse homologue of the Dent disease gene, CLCN5, implicated in X-linked hereditary nephrolithiasis|br/||br/|
Nephrolithiasis, kidney stones or renal calculi are all different names given to the hard mass that is usually formed because of the crystals present in the urine. However, chemicals and natural compounds inside urine may also prevent its formation.
However, supplements do. kidney disease, the use of calcium supplements and calcium-containing preparations should be. Nephrolithiasis is the medical term
Distilled water for kidney stones - Experienced my 2nd kidney stone yesterday. How can I prevent passing another? Im 26 years old, and yesterday I passed a kidney stone. This was my second experience with a kidney stone, as I also passed one about 15-months ago. As anybody that has experie Diet modification. You can have your urine analyzed for kidney stone risk factors. My usual recommendations are 1) increase plain water to at least 2 liters a day 2) decrease sodium intake 3) decrease animal protein intake 4) add a teaspoon of real lemon juice to diet daily.
Kidney stones do a great impact of the health of the patients kidney, we must pay attention to scientific treatment, do not delay the treatment of time, for each kidney stone disease patients recover soon, the following is a detailed description about
Sima is a traditional Finnish drink that is basically hard lemonade.... In a large non-reactive pot (stainless steel or ceramic coated, NOT aluminum), boil 3 liters (+ 1 cup to allow for evaporation, spillage ect.) of water with 2-3 cups white sugar, brown sugar, honey or any combo thereof (more sugar = more alcohol). When dissolved, add 2-4 thinly sliced lemons (some folks carefully peel and add the zest, cut away and discard the pith and add remaining pulp. too much pith can cause bitterness). Let simmer covered 15-30 minutes to allow peels to release lemon oil. Pulp should be partly disintegrated, releasing lemon juice.. Cool to room temp. (75°f/25°c). Placing pot in a sinkful of cool water will speed the process. While cooling, fill a small jar or glass half way with room temp. tap water. Sprinkle enough yeast to cover water surface (baking yeast for traditional low alcohol [1-5%] method, champagne or wine yeast for high alcohol [8-18%]). Do not stir or shake... wait 10 min. or until all ...
Many studies compared the serum/plasma 1,25 dihydroxyvitamin D₃ (1,25(OH)₂D) and 25 hydroxyvitamin D₃ (25(OH)D) between people with and without nephrolithiasis, and their results were conflicting. After systematically searching PubMed, Web of Science, The Cochrane Library, CNKI, and the Wanfang Database, we conducted a meta-analysis. Thirty-two observational studies involving 23,228 participants were included. Meta-analysis of these studies showed that of stone formers (SFs), calcium SFs had significantly higher concentrations of 1,25(OH)₂D (weighted mean difference (WMD), 10.19 pg/mL; 95% confidence interval (CI), 4.31-16.07; p = 0.0007 and WMD, 11.28 pg/mL; 95% CI, 4.07-18.50; p = 0.002, respectively) than non-stone formers, while the levels of 25(OH)D (WMD, 0.88 ng/mL; 95% CI, -1.04-2.80; p = 0.37 and WMD, -0.63 ng/mL; 95% CI, -2.72-1.47; p = 0.56, respectively) are similar. Compared with controls and normocalciuria SFs, hypercalciuria SFs had increased circulating 1,25(OH)₂D (WMD, 9.41 pg
Lei and Tulip happily sit at their lemonade stand, awaiting customers. Tulip sighs contently, and Lei pours her some lemonade. Tulip gladly drinks it, while Giggles, noticing they are out of lemonade, grabs a knife and a lemon. She gets ready to cut into the lemon, but she makes sure to move her...
Popular hives allergic reaction to this product: question Mertle : Has any person ever had an allergic reaction to a moment lemonade nations Had an allergic reaction to Country Time Lemonade, broke out in hives all more than my physique. My throat started to close, I was vomiting and had diahrea faint response, also Very best . response of robgently Yes. There is not a lot in the way of lemon in it Mist.Ich favor as an alternative of true lemonade. Know better? Leave your own answer in. Urticaria or Hives Treatment. ...
Summer E-Liquid by The Lemonade House 10ml. Cool off with another one of the lemonade classics! This time they bring together the tart and tangy inhale of lemonade
Lemonade in the U.S. is sweet and flat - delicious and uncomplicated. In England, lemonade is fizzy and sour and when I look back on living there, I seem to remember drinking it by the gallon (I hope this isnt true, for the sake of my teeth). Ive found fizzy lemonade once or twice in the U.S. - usually Fentimans, which contains ginger and other botanicals and is completely wonderful. As tasty as it is, though, its both expensive and tough to find, so I thought Id try my hand at making my own ...
Shamir Tuchman, MD, is a pediatric nephrologist with a special interest in pediatric kidney stone disease as well as calcium, phosphorus, and vitamin D metabolism. He has both clinical and research expertise in determinants of stone risk in children, bone mineral metabolism alterations in hypercalciuria, and vitamin D status in kidney transplant patients.. ...
Worcester, Elaine M.; Coe, Fredric L. (2008). "Nephrolithiasis". Primary Care: Clinics in Office Practice. 35 (2): 369-391. doi ...
Halabe A, Sperling O (1994). "Uric acid nephrolithiasis". Mineral and Electrolyte Metabolism. 20 (6): 424-31. PMID 7783706. " ...
Nephrolithiasis refers to the presence of such stones in the kidneys. Calyceal calculi are aggregations in either the minor or ... A distinction between nephrolithiasis and urolithiasis can be made because not all urinary stones (uroliths) form in the kidney ... 37: Nephrolithiasis". In Brenner BM (ed.). Brenner and Rector's The Kidney. 1 (8th ed.). Philadelphia: WB Saunders. pp. 1299- ... Nephrolithiasis~Overview at eMedicine § Background. Pearle MS, Calhoun EA, Curhan GC (2007). "Ch. 8: Urolithiasis" (PDF). In ...
When accompanied by a specific type of kidney stone (nephrolithiasis), it is sometimes referred to as "iminoglycinuria, type II ... Oberiter V, Puretić Z, Fabecić-Sabadi V (Apr 1978). "Hyperglycinuria with nephrolithiasis". European Journal of Pediatrics. 127 ... a hereditary disorder associated with nephrolithiasis". The American Journal of Medicine. 23 (3): 408-415. doi:10.1016/0002- ...
AVPR2 Nephrolithiasis, type I; 310468; CLCN5 Nephrolithiasis/osteoporosis, hypophosphatemic, 1; 612286; SLC34A1 Nephrolithiasis ...
Buckalew VM Jr (1989). "Nephrolithiasis in renal tubular acidosis". The Journal of Urology. 141 (3 (part 2)): 731-737. doi: ...
Buckalew VM (March 1989). "Nephrolithiasis in renal tubular acidosis". The Journal of Urology. 141 (3 Pt 2): 731-7. doi:10.1016 ...
Bennett S, Hoffman N, Monga M (December 2004). "Ephedrine- and guaifenesin-induced nephrolithiasis". J Altern Complement Med. ...
Nephrolithiasis~Overview at eMedicine § Background. "eMedicine - Nephrolithiasis: Acute Renal Colic: Article by Stephen W ... Lipkin, Michael; Shah, Ojas (2006-01-01). "The Use of Alpha-Blockers for the Treatment of Nephrolithiasis". Reviews in Urology ...
... nephrolithiasis). Cases of recurrent kidney stone formation may warrant evaluation for possible underlying metabolic ... "Does medullary sponge kidney cause nephrolithiasis?" (PDF). American Journal of Roentgenology. 155 (2): 299-302. doi:10.2214/ ...
"Nephrolithiasis related to inborn metabolic diseases". Pediatric Nephrology. 25 (3): 415-24. doi:10.1007/s00467-008-1085-6. PMC ...
Nephrolithiasis: Acute Renal Colic, Stephen W Leslie. eMedicine. MedlinePlus Encyclopedia: 003131. ...
Frymoyer, PA; Scheinman SJ; Dunham PB; Jones DB; Hueber P; Schroeder ET (1991). "X-linked recessive nephrolithiasis with renal ...
Fang, LST (2009). "Chapter 135: Approach to the Paient with Nephrolithiasis". In Goroll, AH; Mulley, AG (eds.). Primary care ... and nephrolithiasis". In Jennette, JC; Olson, JL; Schwartz, MM; et al. (eds.). Heptinstall's Pathology of the Kidney. 2 (6th ed ... with 5 millimeter sections is the diagnostic modality of choice in the radiographic evaluation of suspected nephrolithiasis. ...
In a 2009 study of 683 children diagnosed in Beijing in 2008 with nephrolithiasis and 6,498 children without nephrolithiasis ... Langman, Craig B. (2009). "Melamine, Powdered Milk, and Nephrolithiasis in Chinese Infants". The New England Journal of ... the risk for nephrolithiasis was 1.7 times higher than in those without melamine exposure, suggesting that the risk of melamine ... "The risk of melamine-induced nephrolithiasis in young children starts at a lower intake level than recommended by the WHO". ...
Langman, Craig (12 March 2009). "Melamine, Powdered Milk, and Nephrolithiasis in Chinese Infants". New England Journal of ...
These include renal colic, polyuria and polydipsia: Renal colic is usually caused by pre-existing nephrolithiasis, as may occur ... Nephrocalcinosis is closely associated with nephrolithiasis, and patients frequently present with both conditions, however ... Gambaro, Giovanni; Trinchieri, Alberto (2016-04-18). "Recent advances in managing and understanding nephrolithiasis/ ... "Randall's plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle". The Journal of Clinical ...
December 2000). "Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder ... Schurman SJ, Norden AG, Scheinman SJ (May 1998). "X-linked recessive nephrolithiasis: presentation and diagnosis in children". ... August 1997). "Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) ... August 1997). "Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) ...
2002). "Bartter syndrome type 3: an unusual cause of nephrolithiasis". Nephrol. Dial. Transplant. 17 (3): 521-3. doi:10.1093/ ...
2001). "Inhibition of oxalate nephrolithiasis with Ammi visnaga (AI-Khillah)". International Urology and Nephrology. 33 (4): ...
"Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate". ... "Emergence of Talanin protein associated with human uric acid nephrolithiasis in the Hominidae lineage". Gene. 339: 131-8. doi: ... "Identification of a new candidate locus for uric acid nephrolithiasis". American Journal of Human Genetics. 68 (5): 1119-29. ...
If neither hyperuricemia nor gout is present, then the risk of uric acid nephrolithiasis can be reduced by the use of ... Hyperuricosuria may be a medical sign of: Gout (very common) Kidney stones of uric acid (uric acid nephrolithiasis) Acute uric ... This syndrome appears not to contribute to gout and to uric acid nephrolithiasis, which is evidence that these two conditions ... CS1 maint: discouraged parameter (link) Mattle D, Hess B (May 2005). "Preventive treatment of nephrolithiasis with alkali ...
Nephrolithiasis~Overview at eMedicine § Pathophysiology.. *^ a b c Coe, FL; Evan, A; Worcester, E (2005). "Kidney stone disease ... Nephrolithiasis~Overview at eMedicine § Background.. *^ a b c Pearle, MS; Calhoun, EA; Curhan, GC (2007). "Ch. 8: Urolithiasis ... in the kidneys is called nephrolithiasis (/ˌnɛfroʊlɪˈθaɪəsɪs/), from nephro- meaning kidney + -lith meaning stone and -iasis ... 13: "Nephrolithiasis".. In Reilly Jr & Perazella 2005, pp. 192-207.. *^ National Kidney and Urologic Diseases Information ...
Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Renal physiology Cotransporter Co- ...
This condition can cause nephrolithiasis (kidney stone), nephrocalcinosis and renal failure. Glyoxylate reductase uses NAD(P)H ...
Dent disease 2 (nephrolithiasis type 2) is associated with the OCRL gene. Both Lowe syndrome (oculocerebrorenal syndrome) and ... which leads to frequent urination Nephrolithiasis (kidney stones) Hypercalciuria (high urine calcium - >300 mg/d or >4 mg/kg ... an X-linked hereditary nephrolithiasis)". Genomics. 29 (3): 598-606. doi:10.1006/geno.1995.9960. hdl:11858/00-001M-0000-0012- ... including X-linked recessive nephrolithiasis with kidney failure, X-linked recessive hypophosphatemic rickets, and both ...
"Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians ... "Meta-analysis of randomized trials for medical prevention of calcium oxalate nephrolithiasis". J. Endourol. 13 (9): 679-85. doi ...
"Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis". J Urol. 158 (6): ...
In kidney stones, calcium oxalate is the most common mineral type (see Nephrolithiasis). Uric acid is the second most common ... Nephrolithiasis (kidney stones) Can cause hydronephrosis (swollen kidneys) and kidney failure Can predispose to pyelonephritis ...
Interstitial nephritis Kidney stones (nephrolithiasis) are a relatively common and particularly painful disorder. A chronic ...
Ettinger B: Recurrence of nephrolithiasis: A six-year prospective study. Am J Med 67: 245, 1979.PubMedCrossRefGoogle Scholar ... Coe FL, Parks JH, Strauss A: Accelerated nephrolithiasis. JAMA 244: 809-810, 1980.PubMedCrossRefGoogle Scholar ... Gutman AB: Uric acid nephrolithiasis. Am J Med 45: 756, 1968.PubMedCrossRefGoogle Scholar ... Coe FL: Hyperuricosuric calcium oxalate nephrolithiasis. Kidney Int 13: 418, 1978.PubMedCrossRefGoogle Scholar ...
Kidney stones result when urine becomes too concentrated and substances in the urine crystalize to form stones. Symptoms arise when the stones begin to move down the ureter causing intense pain. Kidney
encoded search term (How are stones prevented in nephrolithiasis?) and How are stones prevented in nephrolithiasis? What to ... Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016 ... How are stones prevented in nephrolithiasis?. Updated: Jan 13, 2020 * Author: Chirag N Dave, MD; Chief Editor: Bradley Fields ... Wang S, Huang X, Xu Q, Xu T. Research Progress of Mechanisms of Ceftriaxone Associated Nephrolithiasis. Mini Rev Med Chem. 2017 ...
Nephrolithiasis is an increasingly prevalent disorder in the elderly, and often coexists with CKD and osteoporosis. This review ... The risk factors for nephrolithiasis in the elderly are similar to those of the general population, and the initial evaluation ... Calcium stone disease is associated with low BMD and older patients with calcium nephrolithiasis should be evaluated by a dual ... Evaluation and Management of Nephrolithiasis in the Aging Population With Chronic Kidney Disease. ...
... or nephrolithiasis) symptoms include vomiting, blood in your urine and more. Find a full list of symptoms and treatments ... Article: Crosstalk between Renal and Vascular Calcium Signaling: The Link between Nephrolithiasis... ...
... Deputy Editor. Melanie S Kim, MD. Melanie S Kim, MD ...
Ask questions and get answers about Nephrolithiasis. Our support group helps people share their own experience. 63 questions, ... Join the Nephrolithiasis group to help and get support from people like you. ... Our support group for Nephrolithiasis has 63 questions and 52 members. Updated 9 Jan 2019. ...
Nephrolithiasis specifically refers to calculi in the kidneys, but renal calculi and ureteral calculi (ureterolithiasis) are ... encoded search term (Nephrolithiasis) and Nephrolithiasis What to Read Next on Medscape ... Nephrolithiasis is a common disease that affects 1 in 11 people in the United States. [2] Incidence and prevalence rates have ... Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016 ...
... , Calcium Oxalate Stone, Calcium Phosphate Stone, Calcium Oxalate Calculi, Calcium Phosphate Calculi, ... Calcium Nephrolithiasis Cysteine Calculi Nephrolithiasis Nephrolithiasis Risk Factors Struvite Nephrolithiasis Uric Acid ... Calcium Nephrolithiasis. Calcium Nephrolithiasis Aka: Calcium Nephrolithiasis, Calcium Oxalate Stone, Calcium Phosphate Stone, ... Nephrolithiasis Obesity Surgery Radiopaque Foreign Body Oxalate Content in Food Nephrolithiasis Imaging Nephrolithiasis Risk ...
Nephrolithiasis of adult: From mechanisms to preventive medical treatment]. Nephrolithiasis is a very common (prevalence around ... Association between low bone mass and the serum RANKL and OPG in patients with nephrolithiasis. Nephrolithiasis is a risk ... Current opinions on nephrolithiasis associated with primary hyperparathyroidism. Nephrolithiasis is a common urological disease ... Changing in gender prevalence of nephrolithiasis. Although nephrolithiasis is a more common disease in men rather than women, ...
... , Urolithiasis Imaging, Ureteral Calculi Imaging, Kidney Stone Imaging, Renal Colic Imaging, Radiolucent ... Nephrolithiasis Imaging. Nephrolithiasis Imaging Aka: Nephrolithiasis Imaging, Urolithiasis Imaging, Ureteral Calculi Imaging, ... Recurrent Nephrolithiasis results in numerous CT Abdomen scans and their associated risks. *See Cancer Risk due to Diagnostic ... These images are a random sampling from a Bing search on the term "Nephrolithiasis Imaging." Click on the image (or right click ...
Renal tubular acidosis in recurrent calcium nephrolithiasis.. Surian M1, Malberti F, Cosci P, Corradi B, Colussi G, De Ferrari ...
Nephrolithiasis specifically refers to calculi in the kidneys, but renal calculi and ureteral calculi (ureterolithiasis) are ... encoded search term (Nephrolithiasis) and Nephrolithiasis What to Read Next on Medscape. Related Conditions and Diseases. * ... Nephrolithiasis Clinical Presentation. Updated: Jun 21, 2018 * Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz ... Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. Clin J Am Soc Nephrol. 2016 ...
There are genetic defects in both phosphate and amino acid transporters leading to nephrolithiasis. This review also explores ... Vezzoli G, Terranegra A, Soldati L (2012) Calcium-sensing receptor gene polymorphisms in patients with calcium nephrolithiasis ... Mapping the gene causing X-linked recessive nephrolithiasis to Xp11.22 by linkage studies. J Clin Investig 91:2351-2357CrossRef ... Risk of nephrolithiasis in primary hyperparathyroidism is associated with two polymorphisms of the calcium-sensing receptor ...
Helping you find trustworthy answers on Uric Acid Nephrolithiasis , Latest evidence made easy ... Find all the evidence you need on Uric Acid Nephrolithiasis via the Trip Database. ... Epidemiology of nephrolithiasis. J Nephrol, 2000. 13 Suppl 3: S45. 12. Halstead, S.B. Epidemiology of bladder stone of children ... Metabolic syndrome and nephrolithiasis: a systematic review and meta-analysis of the scientific evidence. J Nephrol, 2014. 27: ...
Hypercalciuric nephrolithiasis is a familial disorder in over 35% of patients and may occur as a monogenic disorder that is ... nephrolithiasis) affects 3-5% of the population and is often associated with hypercalciuria. ... Genetic causes of hypercalciuric nephrolithiasis Pediatr Nephrol. 2009 Dec;24(12):2321-32. doi: 10.1007/s00467-008-0807-0. Epub ... Hypercalciuric nephrolithiasis is a familial disorder in over 35% of patients and may occur as a monogenic disorder that is ...
Helping you find trustworthy answers on Uric Acid Nephrolithiasis , Latest evidence made easy ... Find all the evidence you need on Uric Acid Nephrolithiasis via the Trip Database. ... Nephrolithiasis is increasingly reported in bottle-nosed dolphins. All cases to date have been ammonium urate nephrolithiasis.A ... Hyperuricemia can reach levels that require use of xanthine oxidase inhibitors to prevent nephrolithiasis. Nephrolithiasis ...
Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis. S J Engle, M G Stockelman, J ... Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis. S J Engle, M G Stockelman, J ... Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis. S J Engle, M G Stockelman, J ... Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis Message Subject (Your Name) has ...
found nephrolithiasis in 17 of 23 pyonephrosis cases and performed nephrectomy in 5 cases [3]. Our patient had lumbar pain as ... A Giant Case of Pyonephrosis Resulting from Nephrolithiasis. Ali Erol,1 Soner Çoban,2 and Ali Tekin3 ...
Stone formation in patients with idiopathic hypercalciuria. Initial calcium phosphate (apatite) crystallization was found in the basement membrane of the thin limbs of the loop of Henle (A) with subsequent extension to the vasa recta (B), then to the interstitial tissue surrounding the terminal (inner medullary) collecting ducts (C), and finally, in the most severe cases, extension to the papillae (D). Erosion of this solid phase into the urinary space (E), which is supersaturated with respect to calcium oxalate (CaOx), may have promoted heterogeneous nucleation and formation of calcium oxalate kidney stones (F ...
... Saika Sharmeen,1 Esra Kalkan,1 Chunhui Yi ... His medical history was significant for nephrolithiasis and ureteral stone removal one year prior to presentation at which time ... nephrocalcinosis with or without nephrolithiasis and (2) interstitial nephritis with or without granulomas. We report a case of ... Both can lead to acute and chronic kidney injury in sarcoidosis by causing nephrolithiasis and nephrocalcinosis. Hypercalcemia ...
Nephrolithiasis. Nephrolithiasis. Kidney stones result when urine becomes too concentrated and substances in the urine ...
Calcium oxalate nephrolithiasis is a relatively common disease. The prevalence in the general population may range from 10 to ... Nephrolithiasis. Kidney Calculi. Kidney Diseases. Urologic Diseases. Urolithiasis. Urinary Calculi. Calculi. Pathological ... Nephrolithiasis Prevention by Lemon Juice (LIMONE). This study is ongoing, but not recruiting participants. ... history of recurrent nephrolithiasis, with one o more calcium oxalate or mixed (calcium oxalate and phosphate, calcium oxalate ...
Pathophysiology of Uric Acid Nephrolithiasis (IUAN). The safety and scientific validity of this study is the responsibility of ... Nephrolithiasis. Kidney Diseases. Urologic Diseases. Urolithiasis. Urinary Calculi. Calculi. Pathological Conditions, ...
Increased urinary oxalate excretion (hyperoxaluria) promotes the formation of calcium oxalate crystals. Monogenic diseases due to hepatic enzyme deficiency result in chronic hyperoxaluria, promoting end-stage renal disease in children and young adults. Ethylene glycol poisoning also results in hyperoxaluria, promoting acute renal failure and frequently death. Stiripentol is an antiepileptic drug used to treat children affected by Dravet syndrome. It has been shown to inhibit neuronal lactate dehydrogenase 5 enzyme. As this isoenzyme is also the last step of hepatic oxalate production, we hypothesized that stiripentol would potentially reduce hepatic oxalate production and urine oxalate excretion. In vitro, stiripentol decreased the synthesis of oxalate by hepatocytes in a dose-dependent manner. In vivo, oral administration of stiripentol significantly reduced urine oxalate excretion in rats. Stiripentol protected the kidneys against calcium oxalate crystal deposits in acute ethylene glycol ...
Preliminary Diagnosis: Nephrolithiasis. I. What imaging technique is first-line for this diagnosis?. *. Computed tomography (CT ... Describe the advantages and disadvantages of this technique for diagnosis of nephrolithiasis.. Advantages. *. Able to locate an ... V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of nephrolithiasis. * Ultrasound ( ... Describe the advantages and disadvantages of this technique for diagnosis of nephrolithiasis. * Advantages ...
"Nutritional Management of Kidney Stones (Nephrolithiasis)." Clinical Nutrition Research 4 (3): 137-152. doi:10.7762/cnr.2015.4. ...
Low bone mineral density (BMD) is common in people with calcium nephrolithiasis. Calcium nephrolithiasis is described as a ... Nephrolithiasis-Associated Bone Disease.. Posted on March 28, 2011. by Dr. Gary Pack ... People with hypocitraturic nephrolithiasis (low citrate urinary stones) benefit by drinking more citrates, either in orange or ... Urinary stone disease (nephrolithiasis) is a risk factor for bone disease (osteoporosis) and hip fractures. ...
BACKGROUND--Renal calculi have been reported to occur in about 10% of patients with chronic sarcoidosis, but nephrolithiasis as ... Sarcoidosis should always be suspected in cases of nephrolithiasis of unknown origin. ... were reviewed in order to identify nephrolithiasis at presentation. RESULTS--Seventeen patients had renal calculi which ...
Ethnic background has minimal impact on the etiology of nephrolithiasis. Download Prime PubMed App to iPhone, iPad, or Android ... "Ethnic Background Has Minimal Impact On the Etiology of Nephrolithiasis." The Journal of Urology, vol. 173, no. 6, 2005, pp. ... Ethnic background has minimal impact on the etiology of nephrolithiasis.. J Urol. 2005 Jun; 173(6):2001-4.JU ... Ethnic Background Has Minimal Impact On the Etiology of Nephrolithiasis. J Urol. 2005;173(6):2001-4. PubMed PMID: 15879804. ...
  • How are stones prevented in nephrolithiasis? (medscape.com)
  • Little is known about the incidence of nephrolithiasis in the U.S. Navy, and Navy pilots must be kidney stone-free and are often referred for treatment of small asymptomatic stones. (urotoday.com)
  • The recurrence rate of nephrolithiasis in patients with stones that form during childhood is poorly defined. (tripdatabase.com)
  • Calcium nephrolithiasis is described as a multisystem disease with complications of urinary stones and osteoporosis. (rainbow.coop)
  • People with hypocitraturic nephrolithiasis (low citrate urinary stones) benefit by drinking more citrates, either in orange or in lemon juice. (rainbow.coop)
  • Kidney stones, or nephrolithiasis, is a common condition in which hard collections, or calculi, form in the renal system, usually in the tube between the kidney and the bladder. (ada.com)
  • Higher urine calcium is a common feature of calcium nephrolithiasis and may be associated with lower bone mineral density in individuals with kidney stones. (ovid.com)
  • These findings suggest that this may be the link between nephrolithiasis and the greater incidence of atherosclerosis and cardiovascular disease in patients with kidney stones. (urotoday.com)
  • In addition to such anatomic abnormalities as ectatic collecting ducts, low levels of urinary inhibitors of stones seem to contribute to the pathogenesis of nephrolithiasis in patients with MSK. (unboundmedicine.com)
  • Objectives Nephrolithiasis (kidney stones) is a common disease with the prevalence that is increasing globally. (bmj.com)
  • Explain how to prevent future stones in a patient who has nephrolithiasis, regardless of cause. (aappublications.org)
  • METHODS: Patients who underwent laparoscopic Roux-en-Y gastric bypass were interviewed regarding development of renal stones and the data was collected prospectively. (sages.org)
  • CONCLUSION: The new incidence of nephrolithiasis after RYGB is only 3.6% and there is a higher chance of developing recurrent real stones in patients with previous nephrolithiasis. (sages.org)
  • Nephrolithiasis, or kidney stone disease, is a condition in which individuals form calculi (stones) within the renal pelvis and tubular lumens. (ahrq.gov)
  • Approximately 80 percent of adults with nephrolithiasis have stones comprised predominately of calcium oxalate and/or calcium phosphate. (ahrq.gov)
  • Most kidney stones consist of calcium oxalate, and higher urinary oxalate increases the risk for calcium oxalate nephrolithiasis. (asnjournals.org)
  • Kidney stones (nephrolithiasis or urolithiasis) affect approximately 12% of men and 5% of women during their lifetime. (unboundedmedicine.com)
  • Nephrolithiasis is observed markedly less commonly, and stones usually consist of calcium phosphate or calcium oxalate [2]. (thefreedictionary.com)
  • Type 2 diabetes is a risk factor for nephrolithiasis in general and has been associated with uric acid stones in particular. (asnjournals.org)
  • INTRODUCTION: The incidence of pediatric nephrolithiasis (kidney stones) has been increasing over the past several years. (bu.edu)
  • The majority of kidney stones are primarily comprised of calcium, and abnormal calcium metabolism and regulation can lead to nephrolithiasis, nephrocalcinosis, and hypercalciuria. (bu.edu)
  • At nephrolithiasis stones are formed in renal pelvis or minor calyces. (backpain-cure.com)
  • So, nephrolithiasis is the stones that occur specifically in the kidney. (healthadvicer.com)
  • Nephrolithiasis is the medical term for kidney stones. (rxlist.com)
  • The condition of having kidney stones is termed nephrolithiasis. (rxlist.com)
  • Nephrolithiasis refers to the presence of insoluble stones in the urinary tract, which form in a complex cascade of events when the concentration of stone-forming salts in urine exceeds the threshold of solubility and precipitation occurs. (empendium.com)
  • Although the economic burden of kidney stones to the healthcare system has been well established for decades, the emerging evidence to support a link to diminished kidney function, end-stage renal disease (ESRD), and possibly death emphasizes the importance of their chronic management and that the consequence of nephrolithiasis extend well beyond the intermittent episodes and the pain they produce. (ajkdblog.org)
  • While genetic causes of nephrolithiasis have been well-described, diet and lifestyle play a central role for the majority of patients with kidney stones. (ajkdblog.org)
  • Nephrolithiasis is a disorder in which small stones - usually formed from calcium and ox-alate - precipitate in the kidney. (karelsavry.us)
  • Nephrolithiasis is a kidney disease in which solid urinary components form crystals, precipitated out of the urine and shaped into stones. (who.int)
  • Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012. (medscape.com)
  • The primary objectives of this study were to determine the incidence of nephrolithiasis, CT scans performed, proportion undergoing treatment, and incidence of stone-related mishaps of Navy pilots compared with other Navy personnel. (urotoday.com)
  • The incidence of nephrolithiasis has been increasing in Korea. (urotoday.com)
  • Without specific pharmacological therapy, the recurrence rate in patient with established diagnosis of nephrolithiasis is extremely high and may range from 15 to 20 percent per year, with a cumulative incidence at five years ranging from 27 to 50 percent.Although genetic factors play an important role in the development of nephrolithiasis , environmental factors such as diet also appear to affect stone formation. (clinicaltrials.gov)
  • The current management of nephrolithiasis lacks a reliable surrogate marker of kidney stone formation to correlate with stone incidence. (terra-media.us)
  • In Queensland, Australia, there is a high incidence of calcium nephrolithiasis (16.8 hospital admissions per 10,000 population) which is among the highest incidences reported for Westernized societies (1). (springer.com)
  • The overall incidence of nephrolithiasis is increasing. (statpearls.com)
  • 1 , 3 , 4 In the United States the prevalence of nephrolithiasis increased from 3.2% in the late 1970s to 5.2% in the 1990s 5 and further to 8.8% in the 2000s, in parallel with the rising incidence of obesity, insulin resistance, and type 2 diabetes mellitus. (abdominalkey.com)
  • The researchers analyzed data from South Carolina from 1997 to 2012, and found that the annual incidence of nephrolithiasis among children and adults rose 16 percent during that time. (ehealth-news.com)
  • Nephrolithiasis incidence rose 15 percent more in blacks than in whites during each five-year period of the study. (ehealth-news.com)
  • Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis. (medscape.com)
  • Nephrolithiasis is associated to chronic kidney disease and is responsible for 2 to 3% of cases of end-stage renal disease, mainly if it is associated to nephrocalcinosis or to a monogenic disorder (1. (urotoday.com)
  • The majority of sarcoid related renal failure in these cases is due to two pathologic processes: (1) nephrocalcinosis with or without nephrolithiasis and (2) interstitial nephritis with or without granulomas. (hindawi.com)
  • Nephrolithiasis and related disorders, such as nephrocalcinosis and hypercalciuria, can lead to long-term kidney problems, including renal scarring, acute and chronic kidney disease, decreased renal function, or end-stage renal disease. (bu.edu)
  • In the past few years, CYP24A1 mutations leading to decreased activity of 24-hydroxylase have been implicated in some cases of idiopathic infantile hypercalcemia as well as nephrolithiasis, nephrocalcinosis, and hypercalciuria. (bu.edu)
  • To determine the clinical characteristics of patients with elevated 1,25(OH)2D, we reviewed clinical records and laboratory data of patients at Boston Children's Hospital with a diagnosis of nephrolithiasis, nephrocalcinosis, or hypercalciuria. (bu.edu)
  • To determine the clinical characteristics of elevated 1,25(OH)2D, we analyzed the data of 40 patients with normal 1,25(OH)2D and 43 patients with elevated 1,25(OH)2D who had a history of nephrolithiasis, nephrocalcinosis, or hypercalciuria. (bu.edu)
  • The patient's medical history was significant for well-controlled hypertension, type 2 diabetes mellitus, hyperlipidemia, and epilepsy, as well as a remote history of nephrolithiasis. (cancernetwork.com)
  • Previous history of nephrolithiasis is a significant predictor of stone risk after laparoscopic RYGB (p = 0.01). (sages.org)
  • If you have a history of nephrolithiasis, it is better to restrict the food rich in oxalate. (healthadvicer.com)
  • The rate of recurrence of nephrolithiasis is 50% at 5 years. (bmj.com)
  • Qaseem and colleagues ( 1 ) did not indicate under what circumstances citrates, thiazides, or allopurinol should be used to avoid a recurrence of nephrolithiasis. (annals.org)
  • DiBianco JM, Jarrett TW, Mufarrij P (2015) Metabolic syndrome and nephrolithiasis risk: should the medical management of nephrolithiasis include the treatment of metabolic syndrome? (springer.com)
  • Therefore, the increased excretion of the components like calcium, urate, oxalate or cysteine results in the development of nephrolithiasis. (healthadvicer.com)
  • [symptoma.com] OUTCOME: The development of nephrolithiasis during follow-up. (symptoma.com)
  • There are a number of causes and risk factors that may contribute to the development of nephrolithiasis and the development of uroliths, such as the oversaturation of stone-forming material's in the cat's urine. (petmd.com)
  • However, the role of dietary oxalate in the pathogenesis of calcium oxalate nephrolithiasis is unclear. (asnjournals.org)
  • Physico-chemical, metabolic and hormonal theories regarding the pathogenesis of calcium oxalate nephrolithiasis do not sufficiently explain many features of this disease. (usu.edu)
  • Epidemiology and economics of nephrolithiasis. (medscape.com)
  • The diagnosis of nephrolithiasis is often made on the basis of clinical symptoms alone, although confirmatory tests are usually performed. (medscape.com)
  • Describe the advantages and disadvantages of this technique for diagnosis of nephrolithiasis. (renalandurologynews.com)
  • V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of nephrolithiasis. (renalandurologynews.com)
  • Definitive diagnosis of nephrolithiasis requires that a renal calculus is seen on imaging or identified in urine on urination. (thecardiologyadvisor.com)
  • In an oft-cited article from 1998 in the Journal of Clinical Urology, unenhanced helical CT began to be called the new gold-standard imaging modality in the diagnosis of nephrolithiasis. (emcurious.com)
  • Ultrasonography seems to have comparable patient outcomes and reduced radiation exposure when compared with CT as the initial imaging modality utilized in the diagnosis of nephrolithiasis. (emcurious.com)
  • We previously found that trimethyltin (TMT), a by-product of plastic stabilisers, can inhibit the H + /K + ATPase activity in renal intercalated cells and alter urinary pH, which is a known risk factor for nephrolithiasis. (bmj.com)
  • Globally, prevalence appears to be increasing since 1970, which may be secondary to dietary shifts towards higher sodium intake, increased animal protein intake, and increased high fructose corn syrup intake promoting obesity, a known risk factor for nephrolithiasis. (thecardiologyadvisor.com)
  • A 28-year-old man is evaluated for recurrent nephrolithiasis. (acpinternist.org)
  • Eighteen months prior to presentation, the patient was evaluated for recurrent nephrolithiasis, constipation, and fatigue. (pubmedcentralcanada.ca)
  • Direct and indirect costs of nephrolithiasis in an employed population: opportunity for disease management? (medscape.com)
  • We sought to estimate the direct and indirect costs of nephrolithiasis for working age adults (18-64) with employer-provided insurance. (nih.gov)
  • Ellison JS et al, 2017: Patient-Reported Outcomes in Nephrolithiasis: Can We Do Better? (storzmedical.com)
  • Home / Disciplines and Products / Urology / Lithotripsy Database / Blog / Database / Ellison JS et al, 2017: Patient-Reported Outcomes in Nephrolithiasis: Can We Do Better? (storzmedical.com)
  • We aimed to determine the prevalence of elevated 1,25(OH)2D among pediatric patients with nephrolithiasis, and to compare clinical outcomes and biochemical findings in patients with normal versus elevated 1,25(OH)2D. (bu.edu)
  • [en.wikipedia.org] This so-called 'tubular proteinuria ' is a good index of proximal tubular damage, but it is not usually detected by routine clinical dipstick testing for proteinuria . (symptoma.com)
  • FRIDAY, Jan. 15, 2016 (HealthDay News) - A growing number of teens, women, and blacks are being diagnosed with nephrolithiasis, according to findings published online Jan. 14 in the Clinical Journal of the American Society of Nephrology . (ehealth-news.com)
  • Nephrology Now » Blog Archive » Prevention of recurrent calcium nephrolithiasis. (nephrologynow.com)
  • Coe FL: Calcium-uric acid nephrolithiasis. (springer.com)
  • Yu TF, Gutman AB: Uric acid nephrolithiasis in gout: Predisposing factors. (springer.com)
  • Among 40 patients with a history of unilateral nephrolithiasis who underwent percutaneous nephrolithotomy between 2010 and 2016, the following data were acquired: body mass index, past medical history, stone characteristics and composition (i.e., calcium oxalate, calcium phosphate, uric acid, and struvite calculi). (springer.com)
  • Uric acid nephrolithiasis can be treated with stone removal therapy, extracorporeal shock wave lithotripsy (ESWL), and/or surgical treatment. (thefreedictionary.com)
  • The purpose of this study was to identify the metabolic features that place patients with type 2 diabetes at increased risk for uric acid nephrolithiasis. (asnjournals.org)
  • The main risk factor for uric acid nephrolithiasis in patients with type 2 diabetes is a low urine pH. (asnjournals.org)
  • This study was conducted to examine the pathophysiologic mechanisms that underlie the strong association between type 2 diabetes and uric acid nephrolithiasis. (asnjournals.org)
  • Uric acid nephrolithiasis may be the final manifestation of various pathophysiological processes. (elsevier.com)
  • This therapy is indicated in this patient with recurrent calcium oxalate nephrolithiasis following small bowel resection unresponsive to other treatments. (acpinternist.org)
  • Wang S, Huang X, Xu Q, Xu T. Research Progress of Mechanisms of Ceftriaxone Associated Nephrolithiasis. (medscape.com)
  • The aim of this study was to assess whether ceftriaxone associated nephrolithiasis develops by the same mechanism, and whether this condition is dose related. (bmj.com)
  • 5 , 7 Because oxalate is a metabolic end product and is excreted unchanged in the urine after absorption in the gastrointestinal tract, clinicians routinely recommend a low-oxalate diet to patients with calcium oxalate nephrolithiasis. (asnjournals.org)
  • There may be no other body of chemistry tests in any branch of medical practice that is potentially as useful and so often indicated, yet so infrequently utilized, as the 24-hour urine test for nephrolithiasis prophylaxis. (statpearls.com)
  • Nephrolithiasis patients were three times more likely to do 24-hour urine testing if they were treated by a nephrologist or urologist compared to a primary care physician. (statpearls.com)
  • The purpose of this review is to simplify the analysis and evaluation of 24-hour urine collections as well as treatment selection, so local practitioners will be more comfortable using and interpreting this important test for their nephrolithiasis patients. (statpearls.com)
  • 9 The increase in nephrolithiasis rates may be a result of the greater sunlight exposure leading to an increase in insensible losses through sweating, and more con-centrated urine. (abdominalkey.com)
  • So, concentrated urine poses a high risk of nephrolithiasis. (healthadvicer.com)
  • Patients with enteric hyperoxaluria and calcium oxalate nephrolithiasis may benefit from treatment with bile salt binders to decrease intestinal oxalate absorption. (acpinternist.org)
  • Sarcoidosis should always be suspected in cases of nephrolithiasis of unknown origin. (bmj.com)
  • While environmental factors, such as poor fluid intake, high-salt diet, and obesity, can play a role, underlying metabolic factors account for at least one-third of cases of nephrolithiasis. (bu.edu)
  • The causes of nephrolithiasis range from your diet, family history to the side-effects of medication. (healthadvicer.com)
  • Teen girls had the highest rate of increase in nephrolithiasis, and they were more common among females aged 10 to 24 than among males in the same age group. (ehealth-news.com)
  • The prevalence of nephrolithiasis is concentrated among working age adults, yet little prior work has examined the economic burden of the disease on employers and their employees. (nih.gov)
  • Somewhat less clear from the present study is the association of nephrolithiasis with mortality. (ajkdblog.org)
  • Adequate lifestyle modification and proper treatment in metabolic syndrome management may both contribute to nephrolithiasis prevention. (dovepress.com)
  • Data from a prospective, randomized, study supports the use of indapamide for the prevention of recurrent calcium nephrolithiasis [Borghi 1993] . (drugs.com)
  • Recent advances in the pathophysiology of nephrolithiasis. (terra-media.us)
  • Secondarily, the study will evaluate the effects of lemon juice supplementation on complications of nephrolithiasis such as urinary tract infections, colic symptoms, and hospitalizations for stone disruption or removal, as well as the effects on urinary factors (such as urinary citrate, oxalate, calcium excretion or pH) that may favor or limit stone formations and the relationships between these effects and the risk of stone recurrence. (clinicaltrials.gov)
  • Nephrolithiasis classically presents as ureteral colic, but may also commonly present with hematuria or urinary tract infection (UTI). (abdominalkey.com)
  • A 55-year-old male was sent from his primary care physician's office with incidental lab findings significant for hypercalcemia and acute kidney injury with past medical history significant for nephrolithiasis. (hindawi.com)
  • Excess 1,25(OH)2D has been shown to be associated with hyperabsorption of calcium in the intestine, nephrolithiasis, hypercalcemia, and hypercalciuria. (bu.edu)
  • A few studies tried to evaluate the effects of lemon juice supplementation in patients with calcium oxalate nephrolithiasis , but the findings were flawed by the retrospective, observational design of the study or by the too small sample size that limited the power of statistical analyses and the reliability of the results. (clinicaltrials.gov)
  • We present our findings of nephrolithiasis following laparoscopic Roux-en-Y gastric bypass. (sages.org)
  • The recent findings of an abnormally faster oxalate self-exchange and higher phosphorylation of band 3 in erythrocytes of idiopathic calcium oxalate stone formers suggest the hypothesis that nephrolithiasis may be a cellular disease, characterized by a defect in the function of the anion-exchange. (usu.edu)
  • Nephrolithiasis is determined based on ultrasonographic findings. (symptoma.com)
  • 2] Most often, the etiology of SCC is long-standing nephrolithiasis, especially the formation of staghorn renal calculi. (cancernetwork.com)
  • These studies have provided valuable insights into the renal tubular pathways that regulate calcium reabsorption and predispose to hypercalciuria and nephrolithiasis. (nih.gov)
  • Renal stone disease (nephrolithiasis) affects 3-5% of the population and is often associated with hypercalciuria. (nih.gov)
  • Bartter syndrome, Dent's disease, autosomal dominant hypocalcemic hypercalciuria (ADHH), hypercalciuric nephrolithiasis with hypophosphatemia, and familial hypomagnesemia with hypercalciuria have helped to identify a number of transporters, channels and receptors that are involved in regulating the renal tubular reabsorption of calcium. (nih.gov)
  • Thus, biochemical and histological changes in these mice mimic the human disease and provide a suitable model of human hereditary nephrolithiasis. (pnas.org)
  • Calcium oxalate nephrolithiasis is a relatively common disease. (clinicaltrials.gov)
  • Nephrolithiasis-Associated Bone Disease. (rainbow.coop)
  • Urinary stone disease (nephrolithiasis) is a risk factor for bone disease (osteoporosis) and hip fractures. (rainbow.coop)
  • BACKGROUND--Renal calculi have been reported to occur in about 10% of patients with chronic sarcoidosis, but nephrolithiasis as a presentation of this disease has not been studied. (bmj.com)
  • Nephrolithiasis is a lifelong disease process. (bmj.com)
  • Nephrolithiasis is considered a systemic disease. (urotoday.com)
  • A link has been established between nephrolithiasis, cardiovascular disease (CVD), the metabolic syndrome and atherosclerosis. (urotoday.com)
  • This study aimed to evaluate serum levels of oxLDL, anti-oxLDL antibodies (oxLDL-ab) and other markers of atherosclerosis in patients with nephrolithiasis, according to the severity of the disease. (urotoday.com)
  • In part 2 of our series of nephrolithiasis we will focus on the factors that predict risk of stone recurrence and clues to search for a rare cause of kidney stone disease. (medpagetoday.com)
  • Some studies have suggested that nephrolithiasis also may increase the risk of chronic kidney disease. (ahrq.gov)
  • Here, Drosophila melanogaster , an emerging model for kidney stone disease research, was adapted as a high throughput functional drug screening platform agnostic of the multifactorial nature of mammalian nephrolithiasis. (biologists.org)
  • Nephrolithiasis is a common disease. (healthadvicer.com)
  • A highly recurrent disease is observed in 10% of patients with nephrolithiasis. (empendium.com)
  • A recent study published in AJKD by Dhondup et al provides a number of helpful insights into the progression of kidney disease in patients with nephrolithiasis. (ajkdblog.org)
  • While bone-mineral disorders are proposed to have an association with cardiovascular mortality in advanced kidney disease, such an association was not clear from this study, as it relates to nephrolithiasis. (ajkdblog.org)
  • We sought to summarize what is currently known about PROMs in urinary stone disease and to characterize use of PROMs in randomized controlled trials (RCTs) for nephrolithiasis. (storzmedical.com)
  • The risk factors for nephrolithiasis in the elderly are similar to those of the general population, and the initial evaluation is the same as for any stone former. (medscape.com)
  • A prediction model of Nephrolithiasis Risk: A population-based cohort study in Korea. (urotoday.com)
  • Obesity is a significant health concern and is associated with an increased risk of nephrolithiasis , particularly in women. (tripdatabase.com)
  • Although such procedures effectively manage obesity-dependent comorbidities, several large, controlled studies have revealed that modern bariatric surgeries increase the risk of nephrolithiasis by approximately twofold. (tripdatabase.com)
  • Nevertheless, the exact relationship between hypercalciuria and the risk of nephrolithiasis with primary hyperparathyroidism is not fully agreed upon 40 Acute reversible kidney injury secondary to bilateral ureteric obstruction. (terra-media.us)
  • Nephrolithiasis is associated with a significantly higher risk of incident wrist but not hip fracture in women and men. (ovid.com)
  • Is oxidized low-density lipoprotein the connection between atherosclerosis, cardiovascular risk and nephrolithiasis? (urotoday.com)
  • Conclusions To our knowledge, this is the first report to demonstrate that occupational exposure to TMT is a potential risk factor for nephrolithiasis. (bmj.com)
  • Medical conditions that increase the risk of nephrolithiasis include primary hyperparathyroidism, 4 obesity, 5 diabetes, 6 and gout. (ahrq.gov)
  • 7 In large observational studies, dietary factors associated with increased risk of nephrolithiasis include low fluid intake and low dietary calcium. (ahrq.gov)
  • 8-11 With respect to fluid intake, different beverage types appear to have different impacts on the risk of nephrolithiasis. (ahrq.gov)
  • These data do not implicate dietary oxalate as a major risk factor for nephrolithiasis. (asnjournals.org)
  • The risk of ischemic stroke was higher in the nephrolithiasis patients. (medsci.org)
  • Background A well-known complication of gout is an increased risk for nephrolithiasis (NL). (bmj.com)
  • Obesity and type 2 diabetes have reached epidemic proportions worldwide ( 1 , 2 ) and have been implicated as risk factors for nephrolithiasis ( 3 , 4 ). (asnjournals.org)
  • The testing is specifically recommended for all pediatric nephrolithiasis patients as well as for adult stone formers who have a significant renal failure or high anesthetic/surgical risk factors. (statpearls.com)
  • A recent study compares CT with ultrasonography as the initial imaging modality in suspected nephrolithiasis, focusing on high-risk diagnoses, radiation exposure, and adverse events in addition to sensitivity and specificity. (emcurious.com)
  • The 1998 study took into account high-risk diagnoses ,other than nephrolithiasis, made using helical CT, and this is cited as a strong advantage over ultrasound for initial evaluation. (emcurious.com)
  • The drug will initially be studied in a rat model of nephrolithiasis and if the drug is shown to reduce risk of new stone formation we will study the drug in patients with nephrolithiasis. (grantome.com)
  • While 50% of patients with nephrolithiasis may be expected to form a recurrent stone within the next 5-7 years, there is a suggestion that all might benefit from basic dietary counseling and risk factor modification. (ajkdblog.org)
  • During the study period, the risk of nephrolithiasis doubled among children, and there was a 45 percent increase in the lifetime risk for women. (ehealth-news.com)
  • OBJECTIVE: Nephrolithiasis is one of the complications associated with Roux-en-Y gastric bypass. (sages.org)
  • Objective: Adaptation of the Clavien-Dindo classification for assessing the severity of complications following the endoscopic treatment of nephrolithiasis and evaluation of its versatility and objectivity. (thefreedictionary.com)
  • More than 1% of working-age adults were treated for nephrolithiasis in 2000. (nih.gov)
  • Although nephrolithiasis may occur at any age, onset is more common in young and middle-aged adults. (ahrq.gov)
  • Nephrolithiasis specifically refers to calculi in the kidneys, but renal calculi and ureteral calculi (ureterolithiasis) are often discussed in conjunction (see the images below). (medscape.com)
  • His medical history was significant for nephrolithiasis and ureteral stone removal one year prior to presentation at which time the serum creatinine was 2.05 mg/dL with a calcium of 10.5 mg/dL. (hindawi.com)
  • Primary ureteroscopy for nephrolithiasis is often completed without prior ureteral stenting. (canjurol.com)
  • One validated instrument has been created in the nephrolithiasis population, while a treatment-specific questionnaire on ureteral stents has also been developed. (storzmedical.com)
  • Rodriguez, "The role of lithium carbonate and lithium citrate in regulating urinary citrate level and preventing nephrolithiasis ," International Journal of Biomedical Science, vol. (thefreedictionary.com)
  • At the present time there are three pharmacologic therapies for calcium nephrolithiasis that have been proven effective in prospective placebo controlled trials, thiazide diuretics, potassium citrate salts, and allopurinol. (grantome.com)
  • Evidence identifying the association between metabolic syndrome and nephrolithiasis is lacking, especially in Taiwan. (dovepress.com)
  • The aim of this study was to investigate the association between nephrolithiasis and metabolic syndrome and its components. (dovepress.com)
  • The results showed a correlation between nephrolithiasis and metabolic syndrome and its components. (dovepress.com)
  • The multivariate-adjusted odds ratio (OR) (95% confidence interval [CI]) of metabolic syndrome for nephrolithiasis was 1.318 (1.083-1.604), with a P -value of 0.006. (dovepress.com)
  • This is the first study in Taiwan to investigate the relationship between metabolic syndrome and nephrolithiasis. (dovepress.com)
  • Establishing if the patient has previously had episodes of renal colic will help determine if this is recurrent or first time nephrolithiasis. (thecardiologyadvisor.com)
  • Urinary saturation with respect to calcium oxalate monohydrate was measured in 111 consecutive patients with calcium nephrolithiasis. (annals.org)
  • Noncontrast helical computed tomography scan (NCCT) is the preferred imaging modality for nephrolithiasis due to its high sensitivity and specificity, and should be ordered as soon as nephrolithiasis is suspected. (bmj.com)
  • HRQOL is impacted in patients with nephrolithiasis and may be related to gender, proximity of a recent colic episode, or treatment modality. (storzmedical.com)
  • More than 5% of the United States population has been diagnosed with nephrolithiasis and about one half of (first-time) stone formers will have a recurrence within 5 years. (nih.gov)
  • The patient underwent ectracorporal shock wave lithotripsy for nephrolithiasis on the right kidney. (blogspot.com)