Neorickettsia sennetsu
Neorickettsia risticii
Neorickettsia
Rickettsiaceae
Sennetsu neorickettsiosis: a probable fish-borne cause of fever rediscovered in Laos. (1/3)
Neorickettsia sennetsu has been described from Japan and Malaysia, causing a largely forgotten infectious mononucleosis-like disease. Because it is believed to be contracted from eating raw fish, frequently consumed in the Lao PDR, we looked for evidence of N. sennetsu among Lao patients and fish. A buffy coat from 1 of 91 patients with undifferentiated fever was positive by 16S rRNA amplification and sequencing and real-time polymerase chain reactions (PCR) targeting two N. sennetsu genes. Lao blood donors and patients with fever, hepatitis, or jaundice (N = 1,132) had a high prevalence (17%) of immunofluorescence assay IgG anti-N. sennetsu antibodies compared with 4% and 0% from febrile patients (N = 848) in Thailand and Malaysia, respectively. We found N. sennetsu DNA by PCR, for the first time, in a fish (Anabas testudineus). These data suggest that sennetsu may be an under-recognized cause of fever and are consistent with the hypothesis that it may be contracted from eating raw fish. (+info)Proteomic analysis of Neorickettsia sennetsu surface-exposed proteins and porin activity of the major surface protein P51. (2/3)
(+info)Legionella pneumophila secretes a mitochondrial carrier protein during infection. (3/3)
(+info)Neorickettsia sennetsu is a type of intracellular bacterium that can cause the infectious disease known as Sennetsu fever. This bacterium is closely related to other Neorickettsia species, such as N. mikurensis and N. risticii, which are associated with other diseases in animals and humans.
Sennetsu fever is a rare but potentially serious illness that is transmitted to humans through the bite of an infected tick or by ingesting raw fish that contain the larval form of the tick. The disease is most commonly found in Japan, although cases have also been reported in other parts of Asia.
Symptoms of Sennetsu fever can include fever, headache, muscle pain, fatigue, and swollen lymph nodes. In severe cases, the infection can lead to complications such as meningitis or encephalitis. Treatment typically involves antibiotics, such as tetracyclines or chloramphenicol, which are effective against intracellular bacteria.
It's worth noting that Neorickettsia sennetsu is not a well-known pathogen, and more research is needed to fully understand its epidemiology, transmission, and clinical manifestations.
Neorickettsia risticii is a bacterial pathogen that causes Potomac horse fever, a disease in horses. It is a intracellular, gram-negative bacterium that is transmitted to horses through the ingestion of infected aquatic insects, such as caddisflies and mayflies. The bacteria then infects the horse's mononuclear cells, causing symptoms such as fever, diarrhea, and laminitis. It can be fatal in some cases.
It is important to note that Neorickettsia risticii is not a virus but a bacteria, it was previously classified as Ehrlichia risticii but later reclassified as Neorickettsia risticii based on genetic and biochemical characteristics.
Neorickettsia is a genus of intracellular bacteria that are known to cause various diseases in animals and humans. These bacteria have a complex life cycle involving arthropod vectors, such as ticks or flies, and vertebrate hosts. They are gram-negative, pleomorphic, and have a small genome size. Some notable species of Neorickettsia include N. risticii, which causes Potomac horse fever, and N. sennetsu, which can cause a mild febrile illness in humans. Infection with these bacteria typically results in symptoms such as fever, headache, muscle pain, and fatigue. Diagnosis of Neorickettsia infections is often challenging due to their intracellular location and the need for specialized laboratory tests. Treatment usually involves antibiotics, such as tetracyclines or chloramphenicol.
Rickettsiaceae is a family of Gram-negative, obligate intracellular bacteria that are primarily parasitic in arthropods and mammals. They are the causative agents of several important human diseases, including typhus fever, Rocky Mountain spotted fever, and rickettsialpox. These bacteria are typically transmitted to humans through the bites of infected arthropods such as ticks, fleas, or lice.
The bacteria in Rickettsiaceae are small, non-motile, and have a unique bipolar appearance with tapered ends. They can only replicate inside host cells, where they manipulate the host cell's machinery to create a protective niche for themselves. This makes them difficult to culture and study outside of their hosts.
Rickettsiaceae bacteria are divided into several genera based on their genetic and antigenic characteristics, including Rickettsia, Orientia, and Coxiella. Each genus contains several species that can cause different diseases in humans. For example, Rickettsia rickettsii is the causative agent of Rocky Mountain spotted fever, while Rickettsia prowazekii causes epidemic typhus.
Overall, Rickettsiaceae bacteria are important pathogens that can cause serious and sometimes fatal diseases in humans. Prompt diagnosis and treatment with appropriate antibiotics is essential for a successful outcome.
Anaplasmataceae infections are a group of diseases caused by bacteria belonging to the family Anaplasmataceae. These bacteria include Anaplasma, Ehrlichia, and Neorickettsia genera, which infect various mammalian hosts, including humans. The most well-known diseases caused by these bacteria are human granulocytic anaplasmosis (HGA), human monocytic ehrlichiosis (HME), and severe fever with thrombocytopenia syndrome (SFTS).
Human granulocytic anaplasmosis (HGA) is caused by Anaplasma phagocytophilum, which infects neutrophils in humans. Symptoms of HGA include fever, headache, muscle aches, and chills. In severe cases, it can lead to complications such as respiratory failure, neurological symptoms, and even death.
Human monocytic ehrlichiosis (HME) is caused by Ehrlichia chaffeensis or Ehrlichia ewingii, which infect monocytes in humans. Symptoms of HME are similar to those of HGA but may also include nausea, vomiting, diarrhea, and rash. Severe cases can lead to complications such as kidney failure, respiratory distress, and neurological symptoms.
Severe fever with thrombocytopenia syndrome (SFTS) is caused by Dabie bandavirus, a member of the genus Bandavirus within the family Phenuiviridae. It was previously classified as a member of the family Anaplasmataceae. SFTS is transmitted to humans through tick bites and causes symptoms such as fever, fatigue, muscle pain, and gastrointestinal symptoms. Severe cases can lead to complications such as multi-organ failure, shock, and death.
Diagnosis of Anaplasmataceae infections typically involves laboratory tests that detect the presence of bacterial DNA or antibodies against the bacteria in the blood. Treatment usually includes antibiotics such as doxycycline, which is effective against all three genera of bacteria within the family Anaplasmataceae. Preventing tick bites through the use of insect repellent and protective clothing can help reduce the risk of infection.
Rickettsiaceae is a family of Gram-negative, aerobic, intracellular bacteria that includes several important human pathogens. Rickettsiaceae infections are diseases caused by these bacteria, which include:
1. Rocky Mountain Spotted Fever (RMSF): Caused by Rickettsia rickettsii and transmitted to humans through the bite of infected ticks. The disease is characterized by fever, headache, muscle pain, and a rash that spreads from the wrists and ankles to the trunk.
2. Epidemic Typhus: Caused by Rickettsia prowazekii and transmitted to humans through the feces of infected lice. The disease is characterized by fever, headache, muscle pain, and a rash that starts on the chest and spreads to the rest of the body.
3. Murine Typhus: Caused by Rickettsia typhi and transmitted to humans through the feces of infected fleas. The disease is characterized by fever, headache, muscle pain, and a rash that starts on the trunk and spreads to the limbs.
4. Scrub Typhus: Caused by Orientia tsutsugamushi and transmitted to humans through the bite of infected chiggers. The disease is characterized by fever, headache, muscle pain, and a rash that starts on the trunk and spreads to the limbs.
5. Rickettsialpox: Caused by Rickettsia akari and transmitted to humans through the bite of infected mites. The disease is characterized by fever, headache, muscle pain, and a rash that starts as papules and becomes vesicular.
These infections are treated with antibiotics such as doxycycline or chloramphenicol. Early diagnosis and treatment are crucial to prevent severe complications and death.
Ehrlichia is a genus of gram-negative, obligate intracellular bacteria that infect and replicate within the vacuoles of host cells. These bacteria are transmitted to humans and animals through the bite of infected arthropods, such as ticks. Infection with Ehrlichia can cause a variety of symptoms, including fever, headache, muscle aches, and gastrointestinal symptoms. Some species of Ehrlichia, such as Ehrlichia chaffeensis and Ehrlichia ewingii, are known to cause human disease, including ehrlichiosis.
Ehrlichiosis is a tick-borne disease that can range in severity from mild to severe and can be fatal if not promptly diagnosed and treated. Symptoms of ehrlichiosis may include fever, headache, muscle aches, fatigue, and gastrointestinal symptoms such as nausea, vomiting, and diarrhea. In some cases, the infection can lead to more serious complications, such as neurological problems, respiratory failure, or kidney failure.
Ehrlichiosis is typically treated with antibiotics, such as doxycycline, which are effective against the bacteria. It is important to seek medical attention promptly if you suspect that you may have been infected with Ehrlichia, as early treatment can help prevent serious complications. Prevention measures, such as using insect repellent and avoiding tick-infested areas, can also help reduce the risk of infection.