Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
Neoplasms
Neoplasms, Cystic, Mucinous, and Serous
Neoplasms, Multiple Primary
Neoplasms, Second Primary
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.
Adenocarcinoma, Mucinous
Myeloproliferative Disorders
Cystadenoma
Neoplasms, Connective and Soft Tissue
Neoplasms, Plasma Cell
Cystadenoma, Mucinous
Ovarian Neoplasms
Gastrointestinal Neoplasms
Carcinoma, Pancreatic Ductal
Neoplasms, Experimental
Neoplasms, Vascular Tissue
Immunohistochemistry
Neoplasms, Radiation-Induced
Adenocarcinoma, Papillary
Carcinoma, Papillary
Testicular Neoplasms
Neoplasms, Muscle Tissue
Neoplasms, Glandular and Epithelial
Cystadenocarcinoma, Mucinous
A malignant cystic or semisolid tumor most often occurring in the ovary. Rarely, one is solid. This tumor may develop from a mucinous cystadenoma, or it may be malignant at the onset. The cysts are lined with tall columnar epithelial cells; in others, the epithelium consists of many layers of cells that have lost normal structure entirely. In the more undifferentiated tumors, one may see sheets and nests of tumor cells that have very little resemblance to the parent structure. (Hughes, Obstetric-Gynecologic Terminology, 1972, p184)
Soft Tissue Neoplasms
Hematologic Neoplasms
Neoplasm Proteins
Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
Neoplasms, Adnexal and Skin Appendage
Neoplasm Staging
Vascular Neoplasms
Palatal Neoplasms
Antigens, Neoplasm
Cystadenocarcinoma
A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)
Heart Neoplasms
Cystadenoma, Serous
A cystic tumor of the ovary, containing thin, clear, yellow serous fluid and varying amounts of solid tissue, with a malignant potential several times greater than that of mucinous cystadenoma (CYSTADENOMA, MUCINOUS). It can be unilocular, parvilocular, or multilocular. It is often bilateral and papillary. The cysts may vary greatly in size. (Dorland, 27th ed; from Hughes, Obstetric-Gynecologic Terminology, 1972)
Tumor Markers, Biological
Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.
Dog Diseases
Neoplasms, Germ Cell and Embryonal
Bone Marrow Neoplasms
Neoplasms, Adipose Tissue
Colorectal Neoplasms
Meningeal Neoplasms
Carcinoma, Acinar Cell
A malignant tumor arising from secreting cells of a racemose gland, particularly the salivary glands. Racemose (Latin racemosus, full of clusters) refers, as does acinar (Latin acinus, grape), to small saclike dilatations in various glands. Acinar cell carcinomas are usually well differentiated and account for about 13% of the cancers arising in the parotid gland. Lymph node metastasis occurs in about 16% of cases. Local recurrences and distant metastases many years after treatment are common. This tumor appears in all age groups and is most common in women. (Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1240; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p575)
Spinal Cord Neoplasms
Benign and malignant neoplasms which occur within the substance of the spinal cord (intramedullary neoplasms) or in the space between the dura and spinal cord (intradural extramedullary neoplasms). The majority of intramedullary spinal tumors are primary CNS neoplasms including ASTROCYTOMA; EPENDYMOMA; and LIPOMA. Intramedullary neoplasms are often associated with SYRINGOMYELIA. The most frequent histologic types of intradural-extramedullary tumors are MENINGIOMA and NEUROFIBROMA.
Adenoma, Oxyphilic
A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
Neoplasm Recurrence, Local
Nervous System Neoplasms
Janus Kinase 2
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
Neoplasm Metastasis
Muscle Neoplasms
Hemangiosarcoma
Carcinoma
Myelodysplastic-Myeloproliferative Diseases
Peripheral Nervous System Neoplasms
Cerebral Ventricle Neoplasms
Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g., CHOROID PLEXUS NEOPLASMS and GLIOMA, SUBEPENDYMAL), metastasize from distant organs, or occur as extensions of locally invasive tumors from adjacent brain structures.
Pleural Neoplasms
Tomography, X-Ray Computed
Common Bile Duct Neoplasms
Cerebellar Neoplasms
Primary or metastatic neoplasms of the CEREBELLUM. Tumors in this location frequently present with ATAXIA or signs of INTRACRANIAL HYPERTENSION due to obstruction of the fourth ventricle. Common primary cerebellar tumors include fibrillary ASTROCYTOMA and cerebellar HEMANGIOBLASTOMA. The cerebellum is a relatively common site for tumor metastases from the lung, breast, and other distant organs. (From Okazaki & Scheithauer, Atlas of Neuropathology, 1988, p86 and p141)
Lipoma
Retrospective Studies
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Neoplasms by Site
Histiocytic Disorders, Malignant
Neoplasms, Neuroepithelial
Ear Neoplasms
Neoplasm Transplantation
Neoplasm Seeding
Neoplasms, Fibroepithelial
Fatal Outcome
Neoplasms, Connective Tissue
Neuroendocrine Tumors
Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
Neoplasm Grading
Primary Myelofibrosis
Polycythemia Vera
A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
Thrombocythemia, Essential
Trophoblastic Neoplasms
Trophoblastic growth, which may be gestational or nongestational in origin. Trophoblastic neoplasia resulting from pregnancy is often described as gestational trophoblastic disease to distinguish it from germ cell tumors which frequently show trophoblastic elements, and from the trophoblastic differentiation which sometimes occurs in a wide variety of epithelial cancers. Gestational trophoblastic growth has several forms, including HYDATIDIFORM MOLE and CHORIOCARCINOMA. (From Holland et al., Cancer Medicine, 3d ed, p1691)
Hemangioma
Head and Neck Neoplasms
Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
Rodent Diseases
Hemangioendothelioma
A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
Adenoma, Pleomorphic
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
Adenocarcinoma, Follicular
Carcinoma, Neuroendocrine
A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
Prognosis
Neurilemmoma
A neoplasm that arises from SCHWANN CELLS of the cranial, peripheral, and autonomic nerves. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous pattern of biphasic fusiform-shaped cells that may have a palisaded appearance. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp964-5)
Biopsy, Fine-Needle
Central Nervous System Neoplasms
Sarcoma
Carcinosarcoma
Carcinogens
Pituitary Neoplasms
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
Histiocytic Sarcoma
Keratoacanthoma
A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
Pseudomyxoma Peritonei
A condition characterized by poorly-circumscribed gelatinous masses filled with malignant mucin-secreting cells. Forty-five percent of pseudomyxomas arise from the ovary, usually in a mucinous cystadenocarcinoma (CYSTADENOCARCINOMA, MUCINOUS), which has prognostic significance. Pseudomyxoma peritonei must be differentiated from mucinous spillage into the peritoneum by a benign mucocele of the appendix. (Segen, Dictionary of Modern Medicine, 1992)
Carcinogenicity Tests
Tests to experimentally measure the tumor-producing/cancer cell-producing potency of an agent by administering the agent (e.g., benzanthracenes) and observing the quantity of tumors or the cell transformation developed over a given period of time. The carcinogenicity value is usually measured as milligrams of agent administered per tumor developed. Though this test differs from the DNA-repair and bacterial microsome MUTAGENICITY TESTS, researchers often attempt to correlate the finding of carcinogenicity values and mutagenicity values.
Leukemia
A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
Infratentorial Neoplasms
Intracranial tumors originating in the region of the brain inferior to the tentorium cerebelli, which contains the cerebellum, fourth ventricle, cerebellopontine angle, brain stem, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS).
Biliary Tract Neoplasms
Iris Neoplasms
Precancerous Conditions
Urethral Neoplasms
Laryngeal Neoplasms
Granulosa Cell Tumor
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Perivascular Epithelioid Cell Neoplasms
A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. These cells do not have a normal anatomic homolog. (From Fletcher CDM, et. al., World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002).
Carcinoma, Adenoid Cystic
Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)
Biopsy
Biopsy, Needle
Immunoenzyme Techniques
Astrocytoma
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
Mutation
Mesenchymoma
Lymphoma, T-Cell
Cat Diseases
Papilloma
Gene Expression Regulation, Neoplastic
Keratin-7
Hypothalamic Neoplasms
Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate from adjacent structures, including the OPTIC CHIASM, optic nerve (see OPTIC NERVE NEOPLASMS), and pituitary gland (see PITUITARY NEOPLASMS). Relatively frequent clinical manifestations include visual loss, developmental delay, macrocephaly, and precocious puberty. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2051)
Oligodendroglioma
A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)
Histiocytoma, Benign Fibrous
A benign tumor composed, wholly or in part, of cells with the morphologic characteristics of HISTIOCYTES and with various fibroblastic components. Fibrous histiocytomas can occur anywhere in the body. When they occur in the skin, they are called dermatofibromas or sclerosing hemangiomas. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 5th ed, p1747)
Meningioma
A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)
Keratins
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Carcinoid Tumor
A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
Lymphoma, B-Cell
Magnetic Resonance Imaging
Maxillary Sinus Neoplasms
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis. (1/40131)
The cyclin-dependent kinase inhibitor p21waf1/Cip1 is a downstream effector of the p53-dependent cell growth arrest. We report herein that p21 was cleaved by caspase-3/CPP32 at the site of DHVD112L during the DNA damage-induced apoptosis of cancer cells. The cleaved p21 fragment could no more arrest the cells in G1 phase nor suppress the cells undergoing apoptosis because it failed to bind to the proliferating cell nuclear antigen (PCNA) and lost its capability to localize in the nucleus. Thus, caspase-3-mediated cleavage and inactivation of p21 protein may convert cancer cells from growth arrest to undergoing apoptosis, leading to the acceleration of chemotherapy-induced apoptotic process in cancer cells. (+info)Respiratory symptoms and long-term risk of death from cardiovascular disease, cancer and other causes in Swedish men. (2/40131)
BACKGROUND: Depressed respiratory function and respiratory symptoms are associated with impaired survival. The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men. METHODS: Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction. RESULTS: During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause). Men with effort-related breathlessness had increased risk of dying from all of the examined diseases. After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% CI : 1.16-1.77), from stroke 1.77 (95% CI: 1.07-2.93), from any cardiovascular disease 1.48 (95% CI : 1.24-1.76), cancer 1.36 (95% CI : 1.11-1.67) and from any cause 1.62 (95% CI: 1.44-1.81). An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded. An independent effect was also found if all deaths during the first half of the follow-up were excluded. Men with cough and phlegm, without breathlessness, also had an elevated risk of dying from cardiovascular disease and cancer, but after adjustment for smoking and other risk factors this was no longer significant. However, a slightly elevated independent risk of dying from any cause was found (RR = 1.18 [95% CI: 1.02-1.36]). CONCLUSION: A positive response to a simple question about effort related breathlessness predicted subsequent mortality from several causes during a follow-up period of 16 years, independently of smoking and other risk factors. (+info)Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity. (3/40131)
Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme of 5-fluorouracil (5-FU) catabolism. We report lymphocytic DPD data concerning a group of 53 patients (23 men, 30 women, mean age 58, range 36-73), treated by 5-FU-based chemotherapy in different French institutions and who developed unanticipated 5-FU-related toxicity. Lymphocyte samples (standard collection procedure) were sent to us for DPD determination (biochemical method). Among the whole group of 53 patients, 19 had a significant DPD deficiency (DD; below 150 fmol min(-1) mg(-1) protein, i.e. less than 70% of the mean value observed from previous population study). There was a greater majority of women in the DD group (15 out of 19, 79%) compared with the remaining 34 patients (15 out of 34, 44%, P<0.014). Toxicity was often severe, leading to patient death in two cases (both women). The toxicity score (sum of WHO grading, theoretical range 0-20) was twice as high in patients with marked DD (below 100 pmol min(-1) mg(-1) protein, n = 11, mean score = 13.2) compared with patients with moderate DD (between 150 and 100 pmol min(-1) mg(-1) protein, n = 8, mean score = 6.8), P = 0.008. In the DD group, there was a high frequency of neurotoxic syndromes (7 out of 19, 37%). The two deceased patients both had severe neurotoxicity. The occurrence of cardiac toxicity was relatively rare (1 out of 19, 5%). These data suggest that women are particularly prone to DPD deficiency and allow a more precise definition of the DD toxicity profile. (+info)Cancer incidence in the south Asian population of England (1990-92). (4/40131)
Cancer incidence among English south Asians (residents in England with ethnic origins in India, Pakistan or Bangladesh) is described and compared with non-south Asian and Indian subcontinent rates. The setting for the study was areas covered by Thames, Trent, West Midlands and Yorkshire cancer registries. The study identified 356 555 cases of incident cancer (ICD9:140-208) registered between 1990 and 1992, including 3845 classified as English south Asian. The main outcome measures were age specific and directly standardized incidence rates for all cancer sites (ICD9:140-208). English south Asian incidence rates for all sites combined were significantly lower than non-south Asian rates but higher than Indian subcontinent rates. English south Asian rates were substantially higher than Indian subcontinent rates for a number of common sites including lung cancer in males, breast cancer in females and lymphoma in both sexes. English south Asian rates for childhood and early adult cancer (0-29 years) were similar or higher than non-south Asian rates. English south Asian rates were significantly higher than non-south Asian rates for Hodgkin's disease in males, cancer of the tongue, mouth, oesophagus, thyroid gland and myeloid leukaemia in females, and cancer of the hypopharynx, liver and gall bladder in both sexes. The results are consistent with a transition from the lower cancer risk of the country of ethnic origin to that of the country of residence. They suggest that detrimental changes in lifestyle and other exposures have occurred in the migrant south Asian population. (+info)Cancer mortality by educational level in the city of Barcelona. (5/40131)
The objective of this study was to examine the relationship between educational level and mortality from cancer in the city of Barcelona. The data were derived from a record linkage between the Barcelona Mortality Registry and the Municipal Census. The relative risks (RR) of death and 95% confidence intervals (CIs) according to level of education were derived from Poisson regression models. For all malignancies, men in the lowest educational level had a RR of death of 1.21 (95% CI 1.13-1.29) compared with men with a university degree, whereas for women a significant decreasing in risk was observed (RR 0.81; 95% CI 0.74-0.90). Among men, significant negative trends of increasing risk according to level of education were present for cancer of the mouth and pharynx (RR 1.70 for lowest vs. highest level of education), oesophagus (RR 2.14), stomach (RR 1.99), larynx (RR 2.56) and lung (RR 1.35). Among women, cervical cancer was negatively related to education (RR 2.62), whereas a positive trend was present for cancers of the colon (RR 0.76), pancreas (RR 0.59), lung (RR 0.55) and breast (RR 0.65). The present study confirms for the first time, at an individual level, the existence of socioeconomic differences in mortality for several cancer sites in Barcelona, Spain. There is a need to implement health programmes and public health policies to reduce these inequities. (+info)p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. (6/40131)
p27kip1 (p27) is a member of the universal cyclin-dependent kinase inhibitor (CDKI) family. p27 expression is regulated by cell contact inhibition and by specific growth factors, such as transforming growth factor (TGF)-beta. Since the cloning of the p27 gene in 1994, a host of other functions have been associated with this cell cycle protein. In addition to its role as a CDKI, p27 is a putative tumor suppressor gene, regulator of drug resistance in solid tumors, and promoter of apoptosis; acts as a safeguard against inflammatory injury; and has a role in cell differentiation. The level of p27 protein expression decreases during tumor development and progression in some epithelial, lymphoid, and endocrine tissues. This decrease occurs mainly at the post-translational level with protein degradation by the ubiquitin-proteasome pathway. A large number of studies have characterized p27 as an independent prognostic factor in various human cancers, including breast, colon, and prostate adenocarcinomas. Here we review the role of p27 in the regulation of the cell cycle and other cell functions and as a diagnostic and prognostic marker in human neoplasms. We also review studies indicating the increasingly important roles of p27, other CDKIs, and cyclins in endocrine cell hyperplasia and tumor development. (+info)Angiogenesis: a new theory for endometriosis. (7/40131)
Excessive endometrial angiogenesis is proposed as an important mechanism in the pathogenesis of endometriosis. Evidence is reviewed for the hypothesis that the endometrium of women with endometriosis has an increased capacity to proliferate, implant and grow in the peritoneal cavity. Data is summarized indicating that the endometrium of patients with endometriosis shows enhanced endothelial cell proliferation. Results are also reviewed indicating that the cell adhesion molecule integrin alphavbeta3 is expressed in more blood vessels in the endometrium of women with endometriosis when compared with normal women. Taken together, these results provide evidence for increased endometrial angiogenesis in women with endometriosis when compared with normal subjects. Endometriosis is one of the family of angiogenic diseases. Other angiogenic diseases include solid tumours, rheumatoid arthritis, psoriasis and diabetic retanopathy. Excessive endometrial angiogenesis suggests novel new medical treatments for endometriosis aimed at the inhibition of angiogenesis. (+info)Osteopenia in the patient with cancer. (8/40131)
Osteopenia is defined as a reduction in bone mass. It is commonly known to occur in elderly people or women who are postmenopausal due to hormonal imbalances. This condition, however, can result because of many other factors, such as poor nutrition, prolonged pharmacological intervention, disease, and decreased mobility. Because patients with cancer experience many of these factors, they are often predisposed to osteopenia. Currently, patients with cancer are living longer and leading more fulfilling lives after treatment. Therefore, it is imperative that therapists who are responsible for these patients understand the risk factors for osteopenia and their relevance to a patient with cancer. (+info)
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Germline mutations as potential causes of childhood solid tumours: Comments on the Norwegian childhood cancer cohort study...
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Psychological distress, chronic conditions and quality of life in elderly hematologic cancer patients: study protocol of a...
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Chemotherapy
Secondary neoplasm[edit]. Development of secondary neoplasia after successful chemotherapy or radiotherapy treatment can occur ... The most common secondary neoplasm is secondary acute myeloid leukemia, which develops primarily after treatment with ... Survivors of childhood cancer are more than 13 times as likely to get a secondary neoplasm during the 30 years after treatment ... "Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukemia". JAMA. 297 (11): ...
Somatic evolution in cancer
... which may be benign neoplasms) or else a malignant neoplasm (cancer). These neoplasms are also indicated, in the diagram below ... The Hallmarks of Cancer as evolutionary adaptations in a neoplasm[edit]. In their landmark paper, The Hallmarks of Cancer,[3] ... Cells in neoplasms compete for resources, such as oxygen and glucose, as well as space. Thus, a cell that acquires a mutation ... Genetic heterogeneity in neoplasms[edit]. There are multiple levels of genetic heterogeneity associated with cancer, including ...
Myeloproliferative neoplasm
Although not a malignant neoplasm like other cancers, MPNs are classified within the hematological neoplasms. There are four ... According to the WHO Classification of Hematopoietic and Lymphoid Neoplasms 2008 myeloproliferative neoplasms are divided into ... The myeloproliferative neoplasms (MPNs), previously myeloproliferative diseases (MPDs), are a group of diseases of the bone ... Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 2013;369:2391-2405 ...
Neoplasm
ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term 'neoplasm' is a synonym of "tumor". 'Neoplasia' denotes the process of the formation of neoplasms/tumors, the process ... "II Neoplasms". World Health Organization. Retrieved 19 June 2014.. *^ a b Abrams, Gerald. "Neoplasia I". Retrieved 23 January ... Malignant neoplasms[edit]. DNA damage[edit]. The central role of DNA damage and epigenetic defects in DNA repair genes in ...
ICD-10 Chapter V: Mental and behavioural disorders
Neoplasms III D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism ...
ICD-10 Chapter IX: Diseases of the circulatory system
Neoplasms III D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism ...
ICD-10 Chapter XXI: Factors influencing health status and contact with health services
Z08) Follow-up examination after treatment for malignant neoplasms. *(Z09) Follow-up examination after treatment for conditions ...
Adrenal medulla
Neoplasms include: *Pheochromocytoma (most common), a catecholamine-secreting tumor of the adrenal medulla[1][5] ...
Small intestine
The small intestine is found in all tetrapods and also in teleosts, although its form and length vary enormously between species. In teleosts, it is relatively short, typically around one and a half times the length of the fish's body. It commonly has a number of pyloric caeca, small pouch-like structures along its length that help to increase the overall surface area of the organ for digesting food. There is no ileocaecal valve in teleosts, with the boundary between the small intestine and the rectum being marked only by the end of the digestive epitheliu.[22] In tetrapods, the ileocaecal valve is always present, opening into the colon. The length of the small intestine is typically longer in tetrapods than in teleosts, but is especially so in herbivores, as well as in mammals and birds, which have a higher metabolic rate than amphibians or reptiles. The lining of the small intestine includes microscopic folds to increase its surface area in all vertebrates, but only in mammals do these develop ...
User:Djd/sandbox/MedNav/Pathology templates
Neoplasm. {{Epithelial neoplasms}}. Medicine. Glandular and epithelial neoplasms (ICD-O 8010-8589). Oncology templates. See ... Neoplasm. {{Tumors}}. Medicine. Pathology: Tumor, Neoplasm, Cancer, and Oncology (C00-D48, 140-239). Oncology templates. Footer ... Eye neoplasm (C69/D31, 190/224). Oncology templates. Footer. Pathology. Sense Organs. {{Eponymous medical signs for eyes and ... Neoplasm. {{Paraneoplastic syndromes}}. Medicine. Paraneoplastic syndromes. Oncology templates. Footer. Composite format.. ...
Ovary
Ovarian neoplasms Germ cell tumor Seen most often in young women or adolescent girls. Other germ cell tumors are: Endodermal ...
Adenomyoma
In obstetrics and gynecology contexts, it is a form of adenomyosis that forms a mass or growth around the tissue of the inner uterus. Most cases of adenomyosis are non-symptomatic. However, it may present with dysmenorrhea and pelvic pain. In the case of juvenile cystic adenomyoma, laparoscopic enucleation results in a statistically and clinically significant reduction in dysmenorrhea, ease in any chronic pelvic pain, and low risk of recurrence.[2] ...
Lichen planus
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Aphthous stomatitis
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Dentin hypersensitivity
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Black hairy tongue
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Mouth ulcer
... creates immunodeficiencies which allow opportunistic infections or neoplasms to proliferate. Bacterial processes leading to ...
Chronic myelomonocytic leukemia
Cazzola M, Malcovati L, Invernizzi R (2011). "Myelodysplastic/myeloproliferative neoplasms". Hematology Am Soc Hematol Educ ... "Myelodysplastic/myeloproliferative neoplasms". Am. J. Clin. Pathol. 132 (2): 281-9. doi:10.1309/AJCPJ71PTVIKGEVT. PMID 19605822 ... classification of the myeloid neoplasms". Blood. 100 (7): 2292-302. doi:10.1182/blood-2002-04-1199. PMID 12239137. Vardiman J, ... 4th WHO classification of myeloid neoplasms (2008)". Indian J Pathol Microbiol. 53 (3): 391-4. doi:10.4103/0377-4929.68240. ...
Gingivitis
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Herpes simplex
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Eagle syndrome
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Behçet's disease
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Granulosa cell tumour
... s are tumours that arise from granulosa cells. They are esterogen secreting tumors and present as large, complex, ovarian masses. These tumours are part of the sex cord-gonadal stromal tumour or non-epithelial group of tumours. Although granulosa cells normally occur only in the ovary, granulosa cell tumours occur in both ovaries and testicles (see Ovarian cancer and Testicular cancer). These tumours should be considered malignant and treated in the same way as other malignant tumours of ovary. The ovarian disease has two forms, juvenile and adult, both characterized by indolent growth,[1] and therefore has high recovery rates.[2][3] The staging system for these tumours is the same as for epithelial tumours and most present as stage I.[4] The peak age at which they occur is 50-55 years, but they may occur at any age. Juvenile granulosa cell tumour is a similar but distinct rare tumour. It too occurs in both the ovary and testis. In the testis it is extremely rare, and has ...
Koplik's spots
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Burning mouth syndrome
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Temporomandibular joint dysfunction
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Idiopathic osteosclerosis
Salivary gland neoplasms *Benign: Basal cell adenoma. *Canalicular adenoma. *Ductal papilloma. *Monomorphic adenoma ...
Aggressive NK-cell leukemia
Chan JK (1998). "Natural killer cell neoplasms". Anat Pathol. 3: 77-145. PMID 10389582. Elaine Sarkin Jaffe; Nancy Lee Harris; ... a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm". Blood. 89 (12): 4501-13. PMID 9192774. Imamura N, ...
Cutaneous horn
Epidermal nevi, neoplasms, cysts. Hidden categories: *All articles with unsourced statements. *Articles with unsourced ...
Skin cancer
Tumors: Skin neoplasm, skin appendages / Adnexal and skin appendage (C44.L40-L68/D23.L15-49, 173/216) ... Tumors: Skin neoplasm, nevi and melanomas (C43/D22, 172/216, ICD-O 8720-8799) ...
Myeloproliferative Neoplasms | SpringerLink
Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are ... The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and ... Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are ... Critical Issues About the Diagnosis of Myeloproliferative Neoplasms: World Health Organization Classification ...
Neoplasms | The BMJ
Neuroendocrine Neoplasms | SpringerLink
Endocrine neoplasms; Islet cell tumors (pancreatic NET); Small cell and large cell... ... Schmitt-Graeff A. (2015) Neuroendocrine Neoplasms. In: Schwab M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. * ... Carcinoid (well differentiated neuroendocrine tumor (NET) of the respiratory and gastrointestinal tract); Endocrine neoplasms; ... Klöppel G (2011) Classification and pathology of gastroenteropancreatic neuroendocrine neoplasms. Endocr Relat Cancer 18:S1-S16 ...
Neoplasm - Wikipedia
ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of ... The term neoplasm is a synonym of "tumor". Neoplasia denotes the process of the formation of neoplasms/tumors, the process ... "II Neoplasms". World Health Organization. Retrieved 19 June 2014.. *^ a b Abrams, Gerald. "Neoplasia I". Retrieved 23 January ... Malignant neoplasms[edit]. DNA damage[edit]. The central role of DNA damage and epigenetic defects in DNA repair genes in ...
Myeloproliferative neoplasms for students
This presentation is prepared for undergraduate students about the various myeloproliferative neoplasms with updated ... Myeloproliferative neoplasms for students * 1. By Dr MONKEZ MYOUSIF Professor of Internal Medicine Zagazig university 2016 ... A. Other myeloproliferative neoplasms (CML, CIMF, PV) B. Myelodysplastic syndromes (MDS) C. Secondary thrombocytosis − ... This presentation is prepared for undergraduate students about the various myeloproliferative neoplasms with updated ...
Kidney Neoplasms - MeSH - NCBI
All MeSH CategoriesDiseases CategoryNeoplasmsNeoplasms by SiteUrogenital NeoplasmsUrologic NeoplasmsKidney NeoplasmsCarcinoma, ... All MeSH CategoriesDiseases CategoryMale Urogenital DiseasesUrogenital NeoplasmsUrologic NeoplasmsKidney NeoplasmsCarcinoma, ... Urogenital Diseases and Pregnancy ComplicationsFemale Urogenital DiseasesUrogenital NeoplasmsUrologic NeoplasmsKidney Neoplasms ... All MeSH CategoriesDiseases CategoryMale Urogenital DiseasesUrologic DiseasesKidney DiseasesKidney NeoplasmsCarcinoma, Renal ...
Bladder Neoplasms | The BMJ
Brain Neoplasms - MeSH - NCBI
NeoplasmsNeoplasms by SiteNervous System NeoplasmsCentral Nervous System NeoplasmsBrain NeoplasmsCerebral Ventricle Neoplasms ... NeoplasmsBrain Stem NeoplasmsCerebellar NeoplasmsNeurocytomaPinealomaSupratentorial NeoplasmsHypothalamic Neoplasms + ... NeoplasmsBrain Stem NeoplasmsCerebellar NeoplasmsNeurocytomaPinealomaSupratentorial NeoplasmsHypothalamic Neoplasms + ... Nervous System NeoplasmsCentral Nervous System NeoplasmsBrain NeoplasmsCerebral Ventricle NeoplasmsChoroid Plexus Neoplasms + ...
Renal Neoplasms
... News-Medical, viewed 06 August 2021, https://www.news-medical.net/health/Renal-Neoplasms.aspx. ... Renal Neoplasms. News-Medical. 06 August 2021. ,https://www.news-medical.net/health/Renal-Neoplasms.aspx,. ... Renal Neoplasms. News-Medical. https://www.news-medical.net/health/Renal-Neoplasms.aspx. (accessed August 06, 2021). ... 2019, February 26). Renal Neoplasms. News-Medical. Retrieved on August 06, 2021 from https://www.news-medical.net/health/Renal- ...
Myeloproliferative neoplasm - Wikipedia
Although not a malignant neoplasm like other cancers, MPNs are classified within the hematological neoplasms. There are four ... According to the WHO Classification of Hematopoietic and Lymphoid Neoplasms 2008 myeloproliferative neoplasms are divided into ... The myeloproliferative neoplasms (MPNs), previously myeloproliferative diseases (MPDs), are a group of diseases of the bone ... Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 2013;369:2391-2405 ...
Neoplasms | Open Library
Treatment Status in Pancreatic Neuroendocrine Neoplasms
Pancreatic neuroendocrine neoplasms (P-NENs) are a group of pathologically and clinically heterogeneous tumors. In the past ... Neuroendocrine neoplasms (NENs) once called carcinoid tumors, endocrine tumors or neuroendocrine tumors (NETs) are a group of ... Pancreatic neuroendocrine neoplasms (P-NENs), commonly be called pancreatic endocrine tumors, insulinoma, gastrinoma or ...
Neoplasms
Sinus Center provides state-of-the-art care to patients with sinus and allergy disorders including treatment of neoplasms. ... Conditions We Treat: Neoplasms. A neoplasm, typically a benign tumor, can behave more aggressively if not fully treated, rarely ... Neoplasms: What You Need to Know. *Some malignant tumors that occur in the nose include esthesioneuroblastoma (olfactory ... in the Head and Neck Cancer Surgery Center and the Department of Neurology and Neurosurgery to treat patients with neoplasms. ...
Myeloproliferative neoplasms | Disease Information
Myeloproliferative neoplasms are a type of blood cancer that includes myelofibrosis, polycythemia vera and essential ... Myeloproliferative Neoplasms. Myeloproliferative neoplasms are a type of blood cancer that includes myelofibrosis, polycythemia ... Myeloproliferative neoplasms (MPNs) are types of blood cancer that begin with an abnormal mutation (change) in a stem cell in ... Is one of a related group of blood cancers known as "myeloproliferative neoplasms (MPNs)" in which bone marrow cells that ...
Neoplasms | ASPE
A number of studies have examined the most common chronic condition clusters in men and women (Ashman et al. 2013, Lochner et al. 2013, Steiner et al. 2013, Steinman et al. 2012, Ward et al. 2013). Exhibit 6 contains chronic condition dyads (2) and triads (3) that were examined in the studies. Although many chronic condition clusters, such as hype ...
How I Treat Myeloproliferative Neoplasms
... sessions on myeloproliferative neoplasms (MPNs) will take place at the ASH Meeting on Hematologic Malignancies. ... How I Treat Myeloproliferative Neoplasms. The following "How I Treat" sessions on myeloproliferative neoplasms (MPNs) took ... He is a physician investigator with a career focus on developing new therapies for patients with myeloproliferative neoplasms ... Ruben Mesa will discuss how he treats problematic cases of patients with the myeloproliferative neoplasms of essential ...
Morphology of Neoplasms
Molecular Genetics in the Diagnosis of Lymphoid Neoplasms
This workshop summary highlights the role of molecular genetic testing in the diagnosis of lymphoid neoplasms, as well as its ... Table 6. Histiocytic Neoplasms Case No.. Panel Diagnosis. Genetic Findings. 135. Orbital mass: Langerhans cell histiocytosis ( ... Low-grade lymphoid neoplasms with genetic events associated with aggressive biology. 36. Chronic lymphocytic leukemia. t(8;14 ... T-cell neoplasms. FISH for inv(14), iso(7q), ALK, DUSP22, TP63 rearrangement. ...
What Are Plasma Cell Neoplasms? What Causes Them?
Plasma cell neoplasms are a group of diseases - some cancerous - where certain blood cells dont work like they should. Learn ... Plasma cell neoplasms can lead to amyloidosis. This is a condition where proteins build up in your organs, like the kidneys and ... In some plasma cell neoplasms, the cells are cancer and form tumors, usually in your bones. The symptoms you get and the ... But with the group of diseases known as plasma cell neoplasms, your body makes too many plasma cells. They make an antibody ...
NCCN Guidelines for Patients® | Myeloproliferative Neoplasms
Myeloproliferative Neoplasms | Co-Payment Assistance Fund
CancerCares Co-Payment Assistance Fund helps people with myeloproliferative neoplasms access the prescribed treatments they ... CancerCare offers support services for people with myeloproliferative neoplasms including counseling, support groups, financial ... Myeloproliferative Neoplasms. Helping people with cancer access the prescribed treatments they need. This includes Essential ...
NCCN Guidelines for Patients® | Myeloproliferative Neoplasms
Myeloproliferative Neoplasms | Leukemia and Lymphoma Society
Population served: People diagnosed with a myeloproliferative neoplasm (MPN) worldwide. Other language(s): Spanish. Mission: To ... To provide a comprehensive, easy to navigate resource hub for the study of Myeloproliferative Neoplasms (MPNs) such as ... Patients Support Resources Other Helpful Organizations Blood Cancer - General Information Myeloproliferative Neoplasms ... Population served: Patients diagnosed with Myeloproliferative Neoplasms (MPNs), caregivers, professionals. Mission: To empower ...
Brain Neoplasms: Practice Essentials, Pathophysiology, Etiology
Primary brain tumors arise from CNS tissue and account for roughly half of all cases of intracranial neoplasms. ... encoded search term (Brain Neoplasms) and Brain Neoplasms What to Read Next on Medscape ... Brain Neoplasms. Updated: Jan 02, 2019 * Author: Bruce M Lo, MD, MBA, CPE, RDMS, FACEP, FAAEM, FACHE; Chief Editor: Barry E ... Neoplasms, brain. CT images of several tumor types. Slide courtesy of UMASS Continuing Education Office. View Media Gallery ...
Neoplasm - Everything2.com
Neoplasm News, Research
Neoplasm News and Research. RSS Neoplasm is an abnormal mass of tissue as a result of neoplasia. Further Reading. *Neoplasm - ... Common drug for autoimmune disease may increase risk of myeloid neoplasms Mayo Clinic researchers have found that azathioprine ... infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of ... a drug commonly used to treat autoimmune disease, may increase the risk of myeloid neoplasms. ...
Myeloproliferative Neoplasms
... are a group of clonal myeloid cell-derived disorders characterized by myeloproliferation without ... Jones AV, Chase A, Silver RT, et al: JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms ... Mehta J, Wang H, Iqbal SU, et al: Epidemiology of myeloproliferative neoplasms in the United States. Leuk Lymphoma 2013:1-6, ... Myeloproliferative neoplasms are a group of clonal myeloid cell-derived disorders characterized by myeloproliferation without ...
Myeloproliferative Neoplasms
The Myeloproliferative Neoplasms Online Medical Reference - definition, incidence, pathophysiology and natural history, signs ... Mutations of JAK2, MPL, or CALR occur in most myeloproliferative neoplasms and serves as a pivotal diagnostic criterion. ... The myeloproliferative neoplasms (MPNs), previously termed the myeloproliferative disorders, are characterized by the clonal ... The evolving genomic landscape of myeloproliferative neoplasms. Hematology Am Soc Hematol Educ Program 2014; 2014:287-296. ...
Digestive System Neoplasms Clinical Research Trials | CenterWatch
Primary Cardiac Neoplasms: Practice Essentials, Pathophysiology, Epidemiology
... of all these neoplasms. The remainder of the pathological spectrum includes benign and malignant cell types. ... encoded search term (Primary Cardiac Neoplasms) and Primary Cardiac Neoplasms What to Read Next on Medscape ... Primary Cardiac Neoplasms. Updated: Mar 06, 2019 * Author: Mary C Mancini, MD, PhD, MMM; Chief Editor: Eric H Yang, MD more... ... The most common primary cardiac tumor is the atrial myxoma, which accounts for 40-50% of all these neoplasms. [1] The remainder ...
MPNsTumorsMalignant neoplasmsPlasma cell neoplasmsBlastic plasmacytoid dendritic celEssential thrombocythemiaDiagnosisTumorType of myeloproliferative neoplasmCancerLandscape of myeloproliferative neoplasmsWashington-Manual-of-MeSearchLesionsMyelofibrosisPolycythemiaChoroid Plexus NeClonalDiseasesLymphoidPatientsNENsBone neoplasmsBreast NeoplasmsTesticular neoplasmsIntracranial neoplasmAbnormal growthTreatmentCancerousPathologySymptomsTissueChronic2017Clinical
MPNs19
- Myeloproliferative neoplasms (MPNs) are clonal stem cell diseases that, under the World Health Organization classification, are subcategorized into eight clinicopathologic entities. (springer.com)
- The myeloproliferative neoplasms ( MPNs ), previously myeloproliferative diseases ( MPDs ), are a group of diseases of the bone marrow in which excess cells are produced. (wikipedia.org)
- Although not a malignant neoplasm like other cancers, MPNs are classified within the hematological neoplasms . (wikipedia.org)
- Myeloproliferative neoplasms (MPNs) are types of blood cancer that begin with an abnormal mutation (change) in a stem cell in the bone marrow. (lls.org)
- This can cause serious health problems such as a stroke, heart attack or pulmonary embolism Is one of a related group of blood cancers known as "myeloproliferative neoplasms" (MPNs) in w. (lls.org)
- Is one of a related group of blood cancers known as "myeloproliferative neoplasms (MPNs)" in which bone marrow cells that produce blood cells develop and function abnormally. (lls.org)
- Polycythemia Vera (PV) Is one of a related group of blood cancers known as "myeloproliferative neoplasms" (MPNs). (lls.org)
- The following "How I Treat" sessions on myeloproliferative neoplasms (MPNs) took place at the 2018 ASH Meeting on Hematologic Malignancies. (hematology.org)
- To provide a comprehensive, easy to navigate resource hub for the study of Myeloproliferative Neoplasms (MPNs) such as Polycythemia Vera, Essential Thrombocythemia and Myelofibrosis. (lls.org)
- The myeloproliferative neoplasms (MPNs), previously termed the myeloproliferative disorders , are characterized by the clonal proliferation of one or more hematopoietic cell lineages, predominantly in the bone marrow, but sometimes in the liver and spleen. (clevelandclinicmeded.com)
- In the 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms, MPNs include chronic myelogenous leukemia (CML), chronic neutrophilic leukemia, polycythemia vera (PV), primary myelofibrosis (PMF), essential thrombocythemia (ET), chronic eosinophilic leukemia, mastocytosis, and unclassifiable MPNs. (clevelandclinicmeded.com)
- 3 Together with the detection of mutant CALR in hematopoietic stem cells, 1 these data define CALR-mutated MPNs as stem cell-derived neoplasms with aberrant and preferential expansion of the megakaryocyte lineage. (hematology.org)
- Myeloproliferative neoplasms (MPNs) are a group of rare diseases in which the bone marrow produces too many blood cells. (froedtert.com)
- Myeloproliferative Neoplasms (MPNs) are blood cancers that occur when the body makes too many white or red blood cells, or platelets. (cancersupportcommunity.org)
- MPNs were called Myeloproliferative Diseases until 2008 when the World Health Organization reclassified them as cancers and renamed them Myeloproliferative Neoplasms. (cancersupportcommunity.org)
- PV is one of three myeloproliferative neoplasms (MPNs). (cancersupportcommunity.org)
- Myeloproliferative neoplasms (MPNs) are a rare, closely-related group of blood disorders in which the bone marrow overproduces red blood cells, white blood cells, or platelets. (childrenshospital.org)
- Myeloproliferative disorders, commonly called myeloproliferative neoplasms (MPNs), are diseases of the bone marrow and blood. (mdanderson.org)
- But first, more about myeloproliferative neoplasms, or MPNs. (cityofhope.org)
Tumors13
- Pancreatic neuroendocrine neoplasms (P-NENs) are a group of pathologically and clinically heterogeneous tumors. (medscape.com)
- Neuroendocrine neoplasms (NENs) once called carcinoid tumors, endocrine tumors or neuroendocrine tumors (NETs) are a group of pathologically and clinically heterogeneous tumors. (medscape.com)
- In some plasma cell neoplasms, the cells are cancer and form tumors, usually in your bones. (webmd.com)
- The tumors you get with plasma cell neoplasms can also damage your bones. (webmd.com)
- Primary brain tumors arise from CNS tissue and account for roughly half of all cases of intracranial neoplasms. (medscape.com)
- Presenting complaints of patients with an intracranial neoplasm tend to be similar for primary brain tumors and intracranial metastases. (medscape.com)
- Although the overall incidence of primary cardiac neoplasms is low (0.0001-0.5% in autopsy series), these cardiac tumors provide unique diagnostic and therapeutic challenges. (medscape.com)
- Calretinin is considered a specific and reliable marker for differentiation of sex cord-stromal tumors in humans, but its expression is demonstrated in all types of canine testicular neoplasms , including germ cells tumor (seminoma) and sex cord-stromal tumors (Sertoli cell and Leydig cell tumors). (thefreedictionary.com)
- Neoplasms are commonly called tumors. (nih.gov)
- Choroidal neoplasms are tumors of the choroid of the eye. (utah.edu)
- The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. (springer.com)
- Endocrine neoplasms ( tumors ) are among the fastest growing tumors in incidence in the United States. (clinicaltrials.gov)
- Plasma cell neoplasms are diseases in which abnormal plasma cells or myeloma cells form tumors in the bones or soft tissues of the body. (oncolink.org)
Malignant neoplasms7
- benign neoplasms , in situ neoplasms , malignant neoplasms , and neoplasms of uncertain or unknown behavior. (wikipedia.org)
- [5] Malignant neoplasms are also simply known as cancers and are the focus of oncology . (wikipedia.org)
- Potentially-malignant neoplasms include carcinoma in situ . (wikipedia.org)
- Malignant neoplasms are commonly called cancer. (wikipedia.org)
- Cancerous in nature, malignant neoplasms can trigger cases of a dangerous disease called hypercalcemia. (reference.com)
- The object of this study was the investigation of the risk of occurrence of malignant neoplasms in 508 patients with Dupuytren's disease (DD) and in 2157 of their 1st degree relatives. (medworm.com)
- There are various benign and malignant neoplasms that may occur in or overlying the nail matrix and in the nailbed, and symptoms may include pain, itching, and throbbing. (wikipedia.org)
Plasma cell neoplasms20
- What Are Plasma Cell Neoplasms? (webmd.com)
- But with the group of diseases known as plasma cell neoplasms, your body makes too many plasma cells. (webmd.com)
- Plasma cell neoplasms range from not much of a problem to life-threatening. (webmd.com)
- Doctors aren't sure, but they believe plasma cell neoplasms likely are related to changes in the genes of some plasma cells. (webmd.com)
- Plasma cell neoplasms can lead to amyloidosis . (webmd.com)
- NCI does not have PDQ evidence-based information about prevention of plasma cell neoplasms (including multiple myeloma). (cancer.gov)
- Plasma cell neoplasms (including multiple myeloma) statistics based on data from large groups of patients to be used as a general guide. (cancer.gov)
- Potential symptoms of plasma cell neoplasms include fatigue, bone pain, weakness and fevers, says the National Cancer Institute. (reference.com)
- Plasma cell neoplasms can cause plasma cells to manufacture the M protein antibody, a fault that leads to abnormally thick blood, explains the NCI. (reference.com)
- Most cancerous plasma cell neoplasms are classifed as plasmacytoma, or multiple myeloma. (reference.com)
- Plasma cell neoplasms are more common in middle-aged people and senior citizens, with males more at risk than females, notes the NCI. (reference.com)
- Physicians typically use blood and urine tests to diagnose plasma cell neoplasms. (reference.com)
- Multiple myeloma, plasmacytoma, lymphoplasmacytic lymphoma, and monoclonal gammopathy of undetermined significance (MGUS) are different types of plasma cell neoplasms. (oncolink.org)
- This PDQ cancer information summary has current information about treatment of plasma cell neoplasms (including multiple myeloma). (oncolink.org)
- Plasma cell neoplasms are diseases in which the body makes too many plasma cells. (oncolink.org)
- Plasma cell neoplasms can be benign (not cancer) or malignant (cancer). (oncolink.org)
- There are several types of plasma cell neoplasms. (oncolink.org)
- Multiple myeloma and other plasma cell neoplasms may cause a condition called amyloidosis. (oncolink.org)
- Age can affect the risk of plasma cell neoplasms. (oncolink.org)
- Tests that examine the blood, bone marrow, and urine are used to detect (find) and diagnose multiple myeloma and other plasma cell neoplasms. (oncolink.org)
Blastic plasmacytoid dendritic cel4
- The U.S. Food and Drug Administration today approved Elzonris (tagraxofusp-erzs) infusion for the treatment of blastic plasmacytoid dendritic cell neoplasm in adults and in pediatric patients, two years of age and older. (news-medical.net)
- This trial follows the recent opening of trials with SL-401 in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) and relapsed/refractory acute myeloid leukemia (AML) and in patients with AML in first complete response (CR) with minimal residual disease (MRD). (cnbc.com)
- A multicenter clinical trial with SL-401 is currently open and accruing patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) and advanced acute myeloid leukemia (AML). (cnbc.com)
- On December 21, 2018, the Food and Drug Administration approved tagraxofusp-erzs (ELZONRIS™, Stemline Therapeutics), a CD123-directed cytotoxin, for blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adults and in pediatric patients 2 years and older. (fda.gov)
Essential thrombocythemia2
- Myeloproliferative neoplasms are a type of blood cancer that includes myelofibrosis, polycythemia vera and essential thrombocythemia. (lls.org)
- Using a case-based approach, Dr. Ruben Mesa will discuss how he treats problematic cases of patients with the myeloproliferative neoplasms of essential thrombocythemia and polycythemia vera. (hematology.org)
Diagnosis8
- 62 per cent) and two patients (3 per cent) had a final histopathological diagnosis of malignant neoplasm. (ingentaconnect.com)
- The differential diagnosis of neuroendocrine neoplasms of the larynx is broad and includes lesions of epithelial, mesenchymal, and neuroectodermal origin. (nih.gov)
- These lesions have overlapping clinical and pathologic aspects and must be carefully considered in the differential diagnosis of laryngeal neoplasms. (nih.gov)
- The radiologic finding of erosion of the skull base by this mass lesion may have contributed to its interpretation as a destructive neoplasm, with the differential diagnosis including chondrosarcoma, metastatic lesion, osteosarcoma, and meningioma. (thefreelibrary.com)
- However, the histology in this case ruled out a diagnosis of neoplasm. (thefreelibrary.com)
- Although myeloproliferative neoplasms can pose health risks, people with these conditions often live for many years after diagnosis. (cancersupportcommunity.org)
- An oncologist is a medical doctor who specializes in the screening, diagnosis, management and treatment of neoplasms. (wisegeek.com)
- Diagnosis and treatment typically depend on several factors, such as the site of the affected tissue, the type of neoplasm and the prognosis or outcome of the disease. (wisegeek.com)
Tumor13
- Neoplasm is an abnormal growth of tissue which, if it forms a mass, is commonly referred to as a tumor . (wikipedia.org)
- Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy . (wikipedia.org)
- Current English, however, both medical and non-medical, uses tumor as a synonym for a neoplasm (a solid or fluid-filled cystic lesion that may or may not be formed by an abnormal growth of neoplastic cells) that appears enlarged in size. (wikipedia.org)
- A neoplasm, typically a benign tumor, can behave more aggressively if not fully treated, rarely giving rise to a cancer. (hopkinsmedicine.org)
- The most common primary cardiac tumor is the atrial myxoma, which accounts for 40-50% of all these neoplasms. (medscape.com)
- The unexpected frequency of human tumor antigens, which can be readily defined at the molecular level by the serological analysis of autologous tumor cDNA expression cloning, indicates that human neoplasms elicit multiple specific immune responses in the autologous host and provides diagnostic and therapeutic approaches to human cancer. (pnas.org)
- Eye neoplasms can affect all parts of the eye , and can be a benign tumor or a malignant tumor ( cancer ). (wikipedia.org)
- As a result, tumor-like growths of undifferentiated cells (neoplasms) develop beneath the egg. (pnas.org)
- Osteosarcoma was the most prevalent bone tumor, accounting for 86.7% of all malignant primary bone neoplasms diagnosed. (scielo.br)
- To develop a genetic, epigenetic, metabolomic, and proteomic profile of endocrine neoplasm that will allow us to distinguish benign from malignant tumor for each of the endocrine histologies under study. (clinicaltrials.gov)
- In this type of plasma cell neoplasm , the abnormal plasma cells ( myeloma cells ) are in one place and form one tumor , called a plasmacytoma . (oncolink.org)
- A brain neoplasm , commonly known as a brain tumor, is a collection of abnormal cells originating within the brain tissue. (wisegeek.com)
- When a tumor forms within the brain in the presence of an existing cancer in another part of the body, it is considered to have metastasized from the original cancer to become a secondary brain neoplasm and is malignant. (wisegeek.com)
Type of myeloproliferative neoplasm2
- In 2014 I was diagnosed with a type of myeloproliferative neoplasm. (sciencebasedmedicine.org)
- The type of myeloproliferative neoplasm is based on whether too many red blood cells, white blood cells, or platelets are being made. (vicc.org)
Cancer18
- A neoplasm can be benign , potentially malignant, or malignant ( cancer ). (wikipedia.org)
- Our team of experts works closely with our colleagues in the Head and Neck Cancer Surgery Center and the Department of Neurology and Neurosurgery to treat patients with neoplasms. (hopkinsmedicine.org)
- He is a co-lead investigator of the clinical trial arm of the National Cancer Institute funded MPD Research Consortium and is an inaugural panel chair for the NCCN Guideline Panel on myeloproliferative neoplasms. (hematology.org)
- Cancer Care offers support services for people with myeloproliferative neoplasms including counseling, support groups, financial assistance, workshops and publications. (cancercare.org)
- IDIBELL Researchers of the Neuro-Oncology Unit of Bellvitge University Hospital - Catalan Institute of Oncology, led by Dr. Jordi Bruna, have successfully tested a new molecule capable of preventing the development of peripheral neuropathy induced by chemotherapy in cancer patients, especially in colon cancer cases, the third most common neoplasm in the world. (news-medical.net)
- CancerNetwork® spoke with Abdulraheem Yacoub, MD, during the American Association for Cancer Research Annual Meeting 2021 to discuss how predictors of response to therapy may be just as important as the development of new therapies for advancing outcomes in myelofibrosis and myeloproliferative neoplasms. (cancernetwork.com)
- Individuals living with myeloproliferative neoplasm (MPN) often face a markedly different experience compared to those patients with other types of blood cancer. (curetoday.com)
- In this special edition of the " CURE Talks Cancer" podcast, we teamed up with our sister publication " OncLive on Air" to speak with a patient-doctor duo on myeloproliferative neoplasms. (curetoday.com)
- With the increasing number of long-term cancer survivors, there is a growing concern about the risk of radiation induced second malignant neoplasm [SMN]. (mdpi.com)
- Has anyone had a follicular neoplasm which turned out to be cancer of the thyroid? (medhelp.org)
- ANDREW T. KUYKENDALL, MD:Yeah, so I'm Andrew Kuykendall.I'm at Moffitt Cancer Center in Tampa, Florida.At Moffitt we are a little bit different than Mays and MD Anderson in certain ways, but we're a comprehensive cancer center in Tampa, and we have a very specialized group of physicians that see malignant hematology patients, and I specifically focus on myeloproliferative neoplasm patients, so that's the majority of my practice. (curetoday.com)
- A plasma cell neoplasm is a disease that causes the human body to produce too many plasma cells, reports the National Cancer Institute. (reference.com)
- In this type of plasma cell neoplasm , less than 10% of the bone marrow is made up of abnormal plasma cells and there is no cancer . (oncolink.org)
- Though most secondary neoplasms are known to be metastatic in nature, some may form in the presence of an undiagnosed cancer. (wisegeek.com)
- Myeloproliferative neoplasms can't be narrowed down to a single cancer, but they can be described by a defining characteristic: too many blood cells. (cityofhope.org)
- In addition, factors such as advanced cancer diagnostics and early initiation of the treatment are fuelling the global malignant neoplasm therapeutics market. (sbwire.com)
- In terms of value, the U.S accounts for a healthy portion of the global malignant neoplasm therapeutics market attributed to the growing demand for cancer treatment in the country. (sbwire.com)
- Intestinal neoplasms can refer to: Small intestine cancer Colorectal cancer This disambiguation page lists articles associated with the title Intestinal neoplasms. (wikipedia.org)
Landscape of myeloproliferative neoplasms2
- The evolving genomic landscape of myeloproliferative neoplasms. (clevelandclinicmeded.com)
- 1,2 This breakthrough dominated the landscape of myeloproliferative neoplasms (MPN) in 2014 and imbued investigators with a similar scholarly frenzy that followed the identification of JAK2 V617F in 2005. (hematology.org)
Washington-Manual-of-Me3
- Myeloproliferative Neoplasms is a topic covered in the Washington Manual of Medical Therapeutics . (unboundmedicine.com)
- Washington Manual , www.unboundmedicine.com/washingtonmanual/view/Washington-Manual-of-Medical-Therapeutics/602798/all/Myeloproliferative_Neoplasms. (unboundmedicine.com)
- Associated Neoplasms is a topic covered in the Washington Manual of Medical Therapeutics . (unboundmedicine.com)
Search2
- Search: 'Neoplasms therapy. (illinois.edu)
- These images are a random sampling from a Bing search on the term "Laryngeal Neoplasm. (fpnotebook.com)
Lesions5
- For lymphoid neoplasms, e.g. lymphoma and leukemia , clonality is proven by the amplification of a single rearrangement of their immunoglobulin gene (for B cell lesions) or T cell receptor gene (for T cell lesions). (wikipedia.org)
- The remainder of brain neoplasms are caused by metastatic lesions. (medscape.com)
- Intracranial lesions mimicking neoplasms. (thefreelibrary.com)
- The majority of these obstructions are part of pulmonary involvement by primary lung neoplasms or metastatic lesions from other organs. (mendeley.com)
- January 21, 2015 -- Ultrasound-guided biopsy of bone neoplasms yields similar accuracy to CT-guided biopsy for evaluating primary and metastatic bone lesions, while saving money, offering patient convenience, and avoiding radiation dose, according to research from the Henry Ford Health System. (auntminnie.com)
Myelofibrosis1
- 47 NCCN Guidelines for Patients ® : Myeloproliferative Neoplasms, 2018 5 Myelofibrosis Initial treatment What is ruxolitinib? (nccn.org)
Polycythemia1
- Depending on the nature of the myeloproliferative neoplasm, diagnostic tests may include red cell mass determination (for polycythemia), bone marrow aspirate and trephine biopsy, arterial oxygen saturation and carboxyhaemoglobin level, neutrophil alkaline phosphatase level, vitamin B 12 (or B 12 binding capacity), serum urate [12] or direct sequencing of the patient's DNA. (wikipedia.org)
Choroid Plexus Ne3
- According to cellular differentiation, number of mitosis and local invasion, choroid plexus neoplasms can be classified as choroid plexus papillomas or carcinomas (KOESTNER et al. (thefreedictionary.com)
- Features such as high mitotic rate, marked necrosis, nuclear atypia and solid growth are considered as malignancy indicators for choroid plexus neoplasms (RIBAS et al. (thefreedictionary.com)
- It should be pointed out, however, that TTR is not entirely specific for choroid plexus neoplasms , since TTR immunoreactivity has been documented in several other neoplasms, retinal pigment epithelium, and hepatocytes. (thefreedictionary.com)
Clonal2
- It is tempting to define neoplasms as clonal cellular proliferations but the demonstration of clonality is not always possible. (wikipedia.org)
- Myeloproliferative neoplasms are a group of clonal myeloid cell-derived disorders characterized by myeloproliferation without dysplasia, bone marrow hypercellularity, and predisposition to thrombosis, hemorrhage, and bone marrow fibrosis. (cancernetwork.com)
Diseases2
- It is one of the three most common myeloproliferative neoplasms (MPN) - rare blood diseases that develop when the bone marrow makes too many blood cells. (cancersupportcommunity.org)
- Myeloproliferative neoplasms are a group of diseases in which the bone marrow makes too many red blood cells, white blood cells, or platelets. (vicc.org)
Lymphoid1
- A variant of t(14;18)-negative nodal diffuse follicular lymphoma (FL) with 1p36 deletion has been proposed in the 2017 World Health Organization (WHO) classification of lymphoid neoplasms. (medscape.com)
Patients6
- He is a physician investigator with a career focus on developing new therapies for patients with myeloproliferative neoplasms and seeking to better quantify the symptom burden these patients face, and as well as improving their quality of life. (hematology.org)
- to increase awareness amongst patients, physicians and caregivers of myeloproliferative neoplasms. (lls.org)
- Dr. Ruben Mesa, from the MPN Education Foundation, discusses various treatment options for myeloproliferative neoplasms, and highlights how advances in research can help patients with the disease and beyond. (curetoday.com)
- Watch our Myeloproliferative Neoplasms Webinar where an expert panel discussed topics highly relevant to patients, caregivers and advocates right now. (curetoday.com)
- as you know, my career passion and focus.So, in addition to taking care of patients with myeloproliferative neoplasms, I also take care of patients with acute leukemias, and a very rare type of leukemia called BPDCN. (curetoday.com)
- Chromogranin A (CgA) is a plasma biomarker widely used in the follow-up of patients with neuroendocrine neoplasms (NENs). (plos.org)
NENs2
- Neuroendocrine neoplams (NENs) are neoplasms with a broad range of morphologic patterns, grade of differentiation, and biological behavior that share common features of neuroendocrine (NE) programming. (springer.com)
- Human Chromogranin A (CgA), a 439-residue-long protein present in the secretory granules of many normal and neoplastic neuroendocrine cells, currently represents the main biomarker for neuroendocrine neoplasms (NENs) [ 1 , 2 ]. (plos.org)
Bone neoplasms2
- In dogs, unlike what is seen in humans and in some other species of domestic animals, malignant bone neoplasms are much more prevalent than benign neoplasms (Brodey 1979, Misdorp 1980, Dorfman et al. (scielo.br)
- Clinical signs associated with primary bone neoplasms depend much more on the location than on the type of the neoplasm itself (Jongeward 1985). (scielo.br)
Breast Neoplasms2
- Breast Neoplasms complications. (illinois.edu)
- Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS. (labome.org)
Testicular neoplasms6
- Testicular neoplasms are relatively uncommon compared with those of other genitourinary organs, accounting for approximately 1% of human malignancies. (thefreedictionary.com)
- High incidence of benign testicular neoplasms diagnosed by ultrasound. (thefreedictionary.com)
- 5,6,7,8] Testicular neoplasms are hypoechoic on Ultrasonogram and show hypointense enhancement on T1W MRI images. (thefreedictionary.com)
- 4) In contrast, other testicular neoplasms in the prepubertal population present later in life. (thefreedictionary.com)
- Rare testicular neoplasms , such as testicular lymphoma, could be evaluated using technetium-99m methoxyisobutyl isonitrile ([sup. (thefreedictionary.com)
- Primary testicular neoplasms are common in dogs greater than 6 years of age and with a mean age of 10 years (Bethany et al. (thefreedictionary.com)
Intracranial neoplasm1
- A broad spectrum of nonneoplastic conditions can radiologically and clinically mimic an intracranial neoplasm. (thefreelibrary.com)
Abnormal growth1
- Myelo" means bone marrow, where the blood cells are made, while "proliferative" refers to the rapid production of cells, and "neoplasm" is an abnormal growth of cells. (childrenshospital.org)
Treatment4
- ABSTRACT: In the treatment of musculoskeletal neoplasms, preservation of limb function and prolongation of survival have improved over the past decade. (healio.com)
- Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. (clinicaltrials.gov)
- News about research and treatment into myeloproliferative neoplasms. (cityofhope.org)
- The global malignant neoplasm treatment market has become increasingly competitive in the recent years with more player joining in. (sbwire.com)
Cancerous1
- Neoplasms may be benign (not cancerous) or malignant (cancerous). (nih.gov)
Pathology1
- Klöppel G (2011) Classification and pathology of gastroenteropancreatic neuroendocrine neoplasms. (springer.com)
Symptoms2
- What Symptoms Are Associated With a Neoplasm? (reference.com)
- Myeloproliferative neoplasms can cause an array of life-altering symptoms. (cityofhope.org)
Tissue9
- Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. (nih.gov)
- Neoplasm is an abnormal mass of tissue as a result of neoplasia. (news-medical.net)
- Primary neoplasms may arise from endocardium, valvular structures, primitive tissue rests, and the conduction system. (medscape.com)
- Secondary or metastatic neoplasms arise from hematologic spread of the originating tissue. (medscape.com)
- A neoplasm is a lump or mass of tissue often caused by neoplasia, the abnormally rapid division and proliferation of cells. (wisegeek.com)
- In a neoplasm, however, these processes are absent, leading to the larger than normal growth of the tissue. (wisegeek.com)
- Generally, a primary neoplasm may form within the actual brain tissue or its supportive tissues, such as the meninges. (wisegeek.com)
- Additionally, a biopsy by stereotactic needle may be taken to obtain a sample of the neoplasm and surrounding tissue for further analysis. (wisegeek.com)
- The very beginning of malignant neoplasm is the occurrence of abnormal patterns of growth in the tissue known as dysplasia or metaplasia. (sbwire.com)
Chronic5
- Certain leukemias, including chronic myelogenous leukemia, are also now considered Myeloproliferative Neoplasms. (cancersupportcommunity.org)
- There are 6 types of chronic myeloproliferative neoplasms. (vicc.org)
- Chronic myeloproliferative neoplasms sometimes become acute leukemia , in which too many abnormal white blood cells are made. (vicc.org)
- Tests that examine the blood and bone marrow are used to detect (find) and diagnose chronic myeloproliferative neoplasms. (vicc.org)
- Additional signs of a brain neoplasm may include impaired cognition , chronic nausea and vomiting , and persistent headache. (wisegeek.com)
20171
- Albany, NY -- ( SBWIRE ) -- 07/26/2017 -- Malignant neoplasm is believed to be one of the extended conditions of neoplasm. (sbwire.com)
Clinical2
- NEW YORK, Dec. 16, 2014 (GLOBE NEWSWIRE) -- Stemline Therapeutics, Inc. (Nasdaq:STML) announced today the initiation of a clinical trial with SL-401 in four rare myeloproliferative neoplasms (MPN). (cnbc.com)
- Moreover, endocrine neoplasms provide an extremely important model for studying the important molecular changes that lead to carcinogenesis because of their diverse clinical behavior, even when having the same TNM stage and histologic features. (clinicaltrials.gov)