Serotonin 5-HT3 Receptor Antagonists
Drug Administration Schedule
Antineoplastic Combined Chemotherapy Protocols
Dose-Response Relationship, Drug
Maximum Tolerated Dose
Drug Therapy, Combination
Neurokinin-1 Receptor Antagonists
Anesthesia Recovery Period
Receptors, Serotonin, 5-HT3
Carbon disulphide absorption during xanthate reagent mixing in a gold mine concentrator. (1/1415)A xanthate reagent mixer at a gold mine concentrator was exposed to carbon disulphide by extensive skin contamination with xanthate powder and solution during the reagent mixing process. Absorption of carbon disulphide was confirmed by the detection of urinary 2-thiothiazolidine-4-carboxylic acid (TTCA). Drager colorimetric tube testing during subsequent mixing recorded a maximum concentration of at least 60 ppm carbon disulphide. An illness consisting of predominantly gastrointestinal symptoms began 20 h after the exposure. Although this may have been due to carbon disulphide toxicity this is by no means certain. The need for engineering controls, impervious protective clothing and full-face respirators with particulate and organic vapour cartridges is discussed. This episode occurred at another mine site, unrelated to Mount Isa Mines Limited. (+info)
Role of dexamethasone dosage in combination with 5-HT3 antagonists for prophylaxis of acute chemotherapy-induced nausea and vomiting. (2/1415)Dexamethasone (20 mg) or its equivalent in combination with 5-HT3 antagonists appears to be the gold-standard dose for antiemetic prophylaxis. Additional to concerns about the use of corticosteroids with respect to enhanced tumour growth or impaired killing of the tumour cells, there is evidence that high-dosage dexamethasone impairs the control of delayed nausea and emesis, whereas lower doses appear more beneficial. To come closer to the most adequate dose, we started a prospective, single-blind, randomized trial investigating additional dosage of 8 or 20 mg dexamethasone to tropisetron (Navoban), a 5-HT3 receptor antagonist, in cis-platinum-containing chemotherapy. After an interim analysis of 121 courses of chemotherapy in 69 patients, we have been unable to detect major differences between both treatment alternatives. High-dose dexamethasone (20 mg) had no advantage over medium-dose dexamethasone with respect to objective and subjective parameters of acute and delayed nausea and vomiting. In relation to concerns about the use of corticosteroids in non-haematological cancer chemotherapy, we suggest that 8 mg or its equivalent should be used in combination with 5-HT3 antagonists until further research proves otherwise. (+info)
A phase I and pharmacokinetic study of losoxantrone and paclitaxel in patients with advanced solid tumors. (3/1415)A Phase I and pharmacological study was performed to evaluate the feasibility, maximum tolerated dose (MTD), dose-limiting toxicities (DLTs), and pharmacokinetics of the anthrapyrazole losoxantrone in combination with paclitaxel in adult patients with advanced solid malignancies. Losoxantrone was administered as a 10-min infusion in combination with paclitaxel on either a 24- or 3-h schedule. The starting dose level was 40 mg/m2 losoxantrone and 135 mg/m2 paclitaxel (as a 24- or 3-h i.v. infusion) without granulocyte colony-stimulating factor (G-CSF). Administration of these agents at the starting dose level and dose escalation was feasible only with G-CSF support. The following dose levels (losoxantrone/paclitaxel, in mg/m2) of losoxantrone and paclitaxel as a 3-h infusion were also evaluated: 50/135, 50/175, 50/200, 50/225, and 60/225. The sequence-dependent toxicological and pharmacological effects of losoxantrone and paclitaxel on the 24- and 3-h schedules of paclitaxel were also assessed. The MTD was defined as the dose at which >50% of the patients experienced DLT during the first two courses of therapy. DLTs, mainly myelosuppression, occurring during the first course of therapy were noted in four of six and five of eight patients treated with 40 mg/m2 losoxantrone and 135 mg/m2 paclitaxel over 24 and 3 h, respectively, without G-CSF. DLTs during the first two courses of therapy were observed in one of six patients at the 50/175 (losoxantrone/paclitaxel) mg/m2 dose level, two of four patients at the 50/200 mg/m2 dose level, one of four patients at the 50/225 mg/m2 dose level, and two of five patients at the 60/225 mg/m2 dose level. The degree of thrombocytopenia was worse, albeit not statistically significant, when 24-h paclitaxel preceded losoxantrone, with a mean percentage decrement in platelet count during course 1 of 80.7%, compared to 43.8% with the reverse sequence (P = 0.19). Losoxantrone clearance was not significantly altered by the sequence or schedule of paclitaxel. Cardiac toxicity was observed; however, it was not related to total cumulative dose of losoxantrone. An unacceptably high rate of DLTs at the first dose level of 40 mg/m2 losoxantrone and 135 mg/m2 paclitaxel administered as either a 24- or 3-h i.v. infusion precluded dose escalation without G-CSF support. The addition of G-CSF to the regimen permitted further dose escalation without reaching the MTD. Losoxantrone at 50 mg/m2 followed by paclitaxel (3-h i.v. infusion) at 175 mg/m2 with G-CSF support is recommended for further clinical trials. (+info)
A phase I study of the lipophilic thymidylate synthase inhibitor Thymitaq (nolatrexed dihydrochloride) given by 10-day oral administration. (4/1415)2-Amino-3,4-dihydro-6-methyl-4-oxo-5-(4-pyridylthio)-quinazoline dihydrochloride (nolatrexed dihydrochloride, Thymitaq, AG337), a specific inhibitor of thymidylate synthase, was developed using protein structure-based drug design. Intravenously administered nolatrexed is active clinically. As oral bioavailability is high (70-100%), nolatrexed was administered orally, 6 hourly for 10 days, at 3-week intervals, and dose escalated from 80 to 572 mg m(-2) day(-1) in 23 patients. Common toxicity criteria (CTC) grade 3 toxicities included nausea, vomiting, stomatitis and liver function test (LFT) abnormalities. Thrombocytopenia (grade 1 or 2) occurred at doses > or = 318 mg m(-2) day(-1) and neutropenia (grade 2) at 429 and 572 mg m(-2) day(-1). An erythematous maculopapular rash occurred at dosages > or = 318 mg m(-2) day(-1) (7 out of 19 patients). LFT abnormalities occurred in two out of six patients (grade 3 or 4 bilirubin and grade 3 alanine transaminase) at 572 mg m(-2) day(-1). Nolatrexed plasma concentrations 1 h after dosing were 6-16 microg ml(-1), and trough 3-8 microg ml(-1), at 572 mg m(-2) day(-1). Inhibition of thymidylate synthase was demonstrated by elevation of plasma deoxyuridine. Six-hourly oral nolatrexed for 10 days was associated with antiproliferative effects, but nausea and vomiting was dose limiting at 572 mg m(-2) day(-1). Nine patients were treated at 429 mg m(-2) day(-1); three out of nine experienced grade 3 nausea, but 17 out of 22 treatment courses were completed (with the co-administration of prophylactic antiemetics) and this dose level could be considered for phase II testing. (+info)
Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer. (5/1415)PURPOSE: To evaluate the feasibility of administering topotecan in combination with paclitaxel and cisplatin without and with granulocyte colony-stimulating factor (G-CSF) support as first-line chemotherapy in women with incompletely resected stage III and stage IV ovarian carcinoma. PATIENTS AND METHODS: Starting doses were paclitaxel 110 mg/m2 administered over 24 hours (day 1), followed by cisplatin 50 mg/m2 over 3 hours (day 2) and topotecan 0.3 mg/m2/d over 30 minutes for 5 consecutive days (days 2 to 6). Treatment was repeated every 3 weeks. After encountering dose-limiting toxicities (DLTs) without G-CSF support, the maximum-tolerated dose was defined as 5 microg/kg of G-CSF subcutaneously starting on day 6. RESULTS: Twenty-one patients received a total of 116 courses at four different dose levels. The DLT was neutropenia. At the first dose level, all six patients experienced grade 4 myelosuppression. G-CSF support permitted further dose escalation of cisplatin and topotecan. Nonhematologic toxicities, primarily fatigue, nausea/vomiting, and neurosensory neuropathy, were observed but were generally mild. Of 15 patients assessable for response, nine had a complete response, four achieved a partial response, and two had stable disease. CONCLUSION: Neutropenia was the DLT of this combination of paclitaxel, cisplatin, and topotecan. The recommended phase II dose is paclitaxel 110 mg/m2 (day 1), followed by cisplatin 75 mg/m2 (day 2) and topotecan 0.3 mg/m2/d (days 2 to 6) with G-CSF support repeated every 3 weeks. (+info)
Phase II trial of paclitaxel and cisplatin in metastatic and recurrent carcinoma of the uterine cervix. (6/1415)PURPOSE: Both paclitaxel and cisplatin have moderate activity in patients with metastatic or recurrent cancer of the cervix, and the combination of these two agents has shown activity and possible synergism in a variety of solid tumors. We administered this combination to patients with metastatic or recurrent cervical cancer to evaluate its activity. PATIENTS AND METHODS: Thirty-four consecutive patients were treated on an outpatient basis with paclitaxel 175 mg/m2 administered intravenously over a 3-hour period followed by cisplatin 75 mg/m2 administered intravenously with granulocyte colony-stimulating factor support. The chemotherapy was administered every 3 weeks for a maximum of six courses. RESULTS: Sixteen patients (47%; 95% confidence interval, 30% to 65%) achieved an objective response, including five complete responses and 11 partial responses. Responses occurred in 28% of patients with disease within the radiation field only and in 57% of patients with disease involving other sites. The median duration of response was 5.5 months, and the median times to progression and survival for all patients were 5 and 9 months, respectively. Grade 3 or 4 toxicities included anemia in 18% of patients and granulocytopenia in 15% of patients. Fifty-three percent of patients developed some degree of neurotoxicity; 21% of cases were grade 2 or worse. CONCLUSION: The combination of paclitaxel with cisplatin seems relatively well tolerated and moderately active in patients with metastatic or recurrent cervical cancer. The significant incidence of neurotoxicity is of concern, and alternative methods of administration of the two agents could be evaluated. Then, further study of this combination, alone or with the addition of other active agents, is warranted. (+info)
Combined irinotecan and oxaliplatin plus granulocyte colony-stimulating factor in patients with advanced fluoropyrimidine/leucovorin-pretreated colorectal cancer. (7/1415)PURPOSE: To evaluate the efficacy and tolerance of combined irinotecan and oxaliplatin in patients with advanced colorectal cancer pretreated with leucovorin-modulated fluoropyrimidines. PATIENTS AND METHODS: Thirty-six patients with metastatic colorectal cancer, who progressed while receiving or within 6 months after discontinuing palliative chemotherapy with fluoropyrimidines/leucovorin, were enrolled onto this study. Treatment consisted of oxaliplatin 85 mg/m2 on days 1 + 15 and irinotecan 80 mg/m2 on days 1 + 8 + 15 every 4 weeks. Depending on the absolute neutrophil counts (ANC) on the day of scheduled chemotherapeutic drug administration, a 5-day course of granulocyte colony-stimulating factor (G-CSF) 5 microg/kg/d was given. RESULTS: The overall response rate was 42% for all 36 assessable patients (95% confidence interval, 26% to 59%), including two complete remissions (6%). Thirteen additional patients (36%) had stable disease, and only eight (22%) progressed. The median time to treatment failure was 7.5 months (range, 1 to 13.5+ months). After a median follow-up time of 14 months, 19 patients (53%) are still alive. Hematologic toxicity was commonly observed, although according to the ANC-adapted use of G-CSF (in 31 patients during 81 of 174 courses), it was generally mild: grade 3 and 4 granulocytopenia occurred in only five and two cases, respectively. The most frequent nonhematologic adverse reactions were nausea/emesis and diarrhea, which were rated severe in 17% and 19%, respectively. CONCLUSION: Our data suggest that the combination of irinotecan and oxaliplatin with or without G-CSF has substantial antitumor activity in patients with progressive fluoropyrimidine/leucovorin-pretreated colorectal cancer. Overall toxicity was modest, with gastrointestinal symptoms constituting the dose-limiting side effects. Further evaluation of this regimen seems warranted. (+info)
Front-line treatment of advanced non-small-cell lung cancer with docetaxel and gemcitabine: a multicenter phase II trial. (8/1415)PURPOSE: To evaluate the tolerance and efficacy of the combination of docetaxel and gemcitabine in patients with advanced non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Fifty-one chemotherapy-naive patients with NSCLC were treated with gemcitabine 900 mg/m2 intravenously on days 1 and 8 and docetaxel 100 mg/m2 intravenously on day 8 with granulocyte colony-stimulating factor (150 microg/m2, subcutaneously) support from day 9 to day 15. Treatment was repeated every 3 weeks. RESULTS: The patients' median age was 64 years. The World Health Organization performance status was 0 to 1 in 39 patients and 2 in 12 patients. Fifteen patients (29%) had stage IIIB disease, and 36 (71%) had stage IV; histology was mainly squamous cell carcinoma (59%). A partial response was achieved in 19 patients (37.5%; 95% confidence interval, 24% to 50%); stable disease and progressive disease were each observed in 16 patients (31.4%). The median duration of response and the time to tumor progression were 5 and 6 months, respectively. The median survival was 13 months, and the actuarial 1-year survival was 50.7%. Grade 4 anemia and thrombocytopenia were rare (2%). Four patients (8%) developed grade 3 or 4 neutropenia, and all were complicated with fever; there was no treatment-related death. Grade 3 or 4 diarrhea occurred in three patients (6%), grade 2 or 3 neurotoxicity in four patients (8%), grade 2 or 3 asthenia in 10 patients (20%), and grade 2 or 3 edema in 10 patients (20%). CONCLUSION: The combination of docetaxel/gemcitabine is well tolerated, can be used for outpatients, and is active for the treatment of advanced NSCLC. This treatment merits further comparison with other cisplatin- or carboplatin-based combinations. (+info)
Nausea is a common sensation of uneasiness or discomfort in the upper stomach with an involuntary urge to vomit. It can be a symptom of various medical conditions, including gastrointestinal disorders, infections, pregnancy, and certain medications. In the medical field, nausea is often evaluated and treated by a healthcare provider to determine the underlying cause and provide appropriate treatment.
Postoperative nausea and vomiting (PONV) is a common complication that occurs after surgery. It is characterized by feelings of nausea (an unpleasant sensation in the stomach) and vomiting (throwing up) that can occur within hours of surgery. PONV can be caused by a variety of factors, including anesthesia, pain medication, and the stress of surgery. It can be a distressing and uncomfortable experience for patients, and in severe cases, it can lead to dehydration, electrolyte imbalances, and other complications. Treatment for PONV typically involves medications to prevent or relieve nausea and vomiting, as well as supportive care to help patients manage their symptoms.
Vomiting is a medical condition characterized by the involuntary and forceful expulsion of the contents of the stomach through the mouth. It is also known as emesis or retching. Vomiting can be a symptom of a variety of medical conditions, including infections, digestive disorders, pregnancy, and certain medications. It can also be a response to toxins, such as those found in certain foods or chemicals. In severe cases, vomiting can lead to dehydration, electrolyte imbalances, and other complications. Treatment for vomiting depends on the underlying cause and may include medications, changes in diet and fluid intake, or other interventions.
Ondansetron is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, surgery, or other medical procedures. It is also used to prevent nausea and vomiting caused by motion sickness or morning sickness during pregnancy. Ondansetron works by blocking the action of chemicals in the brain that trigger the feeling of nausea and vomiting. It is available in tablet, oral solution, and injectable forms.
Motion sickness, also known as seasickness, car sickness, or vertigo, is a common condition that affects people when they experience a mismatch between the sensory information received by the brain and the body's actual movement. The brain relies on information from the inner ear, which detects changes in head position and movement, and the eyes, which provide visual cues about the environment. When these two sources of information do not match, the brain becomes confused and can trigger symptoms such as dizziness, nausea, vomiting, sweating, and headache. Motion sickness can occur in a variety of situations, including traveling in a car, plane, or boat, riding a roller coaster, or watching a 3D movie. It is more common in children and young adults, and some people may be more susceptible to motion sickness than others. Treatment for motion sickness may include over-the-counter medications such as antihistamines or motion sickness bands, as well as lifestyle changes such as avoiding triggers, getting plenty of rest, and staying hydrated. In severe cases, medical treatment may be necessary.
Anticipatory vomiting is a type of vomiting that occurs in response to a specific trigger or anticipation of a trigger, such as the thought of food or the sight of a particular food. It is a common symptom of various medical conditions, including motion sickness, postoperative nausea and vomiting, and certain types of cancer and chemotherapy. Anticipatory vomiting can also be a side effect of certain medications, such as antidepressants and chemotherapy drugs. Treatment for anticipatory vomiting may involve medications, behavioral therapy, or a combination of both.
Morning sickness is a common condition experienced by pregnant women during the first trimester of pregnancy. It is characterized by feelings of nausea and vomiting, usually in the morning, although it can occur at any time of the day. The severity of morning sickness can vary from mild to severe, and it can affect a woman's daily activities and quality of life. Morning sickness is caused by hormonal changes that occur during pregnancy, particularly an increase in the hormone human chorionic gonadotropin (hCG). The exact mechanism of how hCG causes morning sickness is not fully understood, but it is believed to affect the digestive system and the brain's response to smells and tastes. While morning sickness can be uncomfortable and disruptive, it is usually not a cause for concern and typically resolves on its own by the end of the first trimester. However, in some cases, severe morning sickness can lead to dehydration, weight loss, and electrolyte imbalances, which may require medical intervention.
Granisetron is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It is a 5-hydroxytryptamine (5-HT3) receptor antagonist, which means it blocks the action of a chemical in the brain that can trigger vomiting. Granisetron is available in both oral and injectable forms and is typically administered before or after exposure to the nausea-inducing agent. It is also sometimes used to treat nausea and vomiting caused by motion sickness or surgery.
Droperidol is a medication that is used to treat nausea and vomiting, particularly in patients who are undergoing chemotherapy or surgery. It is also used to treat anxiety and agitation, and to control hallucinations and delirium in patients with certain mental health conditions. Droperidol is a type of medication called a dopamine antagonist, which means that it blocks the effects of dopamine, a neurotransmitter that plays a role in regulating movement, mood, and other bodily functions. It is available in both oral and injectable forms, and is typically administered by a healthcare professional.
Prochlorperazine is a medication that belongs to a class of drugs called phenothiazines. It is primarily used to treat a variety of conditions, including nausea and vomiting, anxiety, and certain types of mental disorders such as schizophrenia and bipolar disorder. Prochlorperazine works by blocking certain receptors in the brain, which can help to reduce symptoms such as anxiety, agitation, and hallucinations. It is available in both oral and injectable forms, and is typically prescribed by a healthcare provider.
Metoclopramide is a medication that is used to treat a variety of gastrointestinal disorders. It is a type of medication called a prokinetic, which means that it helps to speed up the movement of food through the digestive system. Metoclopramide is often used to treat conditions such as nausea and vomiting, gastroparesis (a condition in which the stomach empties too slowly), and acid reflux disease (GERD). It is available in both oral and injectable forms, and is typically prescribed by a doctor or other healthcare professional.
Hyperemesis gravidarum is a severe form of nausea and vomiting that occurs during pregnancy. It is characterized by persistent and excessive vomiting, dehydration, and weight loss. The condition can be life-threatening if left untreated and can lead to complications such as electrolyte imbalances, kidney damage, and malnutrition for both the mother and the developing fetus. Hyperemesis gravidarum typically occurs during the first trimester of pregnancy but can persist throughout the pregnancy. Treatment may include medications, hospitalization, and nutritional support.
Pain, Postoperative refers to the discomfort or pain experienced by a patient after undergoing surgery. It is a common and expected complication of surgery, and can range from mild to severe. Postoperative pain can be caused by a variety of factors, including tissue damage, inflammation, and nerve stimulation. It is typically managed with a combination of pain medications, such as opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and local anesthetics, as well as other treatments such as physical therapy, ice packs, and relaxation techniques. Proper management of postoperative pain is important for promoting healing, reducing the risk of complications, and improving the patient's overall comfort and quality of life.
Quinuclidines are a class of organic compounds that contain a quinuclidine ring, which is a six-membered ring with four nitrogen atoms and two carbon atoms. They are structurally related to the amphetamines and have been used as stimulants and nootropics. Some quinuclidines, such as pyrovalerone, have also been used as analgesics and anticonvulsants. In the medical field, quinuclidines are not commonly used and their therapeutic potential is not well established.
In the medical field, neoplasms refer to abnormal growths or tumors of cells that can occur in any part of the body. These growths can be either benign (non-cancerous) or malignant (cancerous). Benign neoplasms are usually slow-growing and do not spread to other parts of the body. They can cause symptoms such as pain, swelling, or difficulty moving the affected area. Examples of benign neoplasms include lipomas (fatty tumors), hemangiomas (vascular tumors), and fibromas (fibrous tumors). Malignant neoplasms, on the other hand, are cancerous and can spread to other parts of the body through the bloodstream or lymphatic system. They can cause a wide range of symptoms, depending on the location and stage of the cancer. Examples of malignant neoplasms include carcinomas (cancers that start in epithelial cells), sarcomas (cancers that start in connective tissue), and leukemias (cancers that start in blood cells). The diagnosis of neoplasms typically involves a combination of physical examination, imaging tests (such as X-rays, CT scans, or MRI scans), and biopsy (the removal of a small sample of tissue for examination under a microscope). Treatment options for neoplasms depend on the type, stage, and location of the cancer, as well as the patient's overall health and preferences.
Cisplatin is a chemotherapy drug that is commonly used to treat various types of cancer, including ovarian, testicular, bladder, and lung cancer. It works by binding to the DNA of cancer cells, which prevents them from dividing and growing. Cisplatin is usually administered intravenously and can cause a range of side effects, including nausea, vomiting, hair loss, and damage to the kidneys and hearing. It is important to note that cisplatin is not effective for all types of cancer and may not be suitable for everyone. The use of cisplatin should be determined by a healthcare professional based on the individual's specific medical needs and circumstances.
Gastroparesis is a medical condition in which the muscles of the stomach do not contract properly, leading to a delay in the emptying of food from the stomach. This can cause a variety of symptoms, including nausea, vomiting, abdominal pain, bloating, and early satiety (feeling full after eating only a small amount of food). Gastroparesis can be caused by a variety of factors, including nerve damage, diabetes, surgery, and certain medications. It is typically diagnosed through a combination of medical history, physical examination, and imaging studies. Treatment for gastroparesis may include dietary changes, medications, and in severe cases, surgery.
Dexamethasone is a synthetic glucocorticoid hormone that is used in the medical field as an anti-inflammatory, immunosuppressive, and antipyretic agent. It is a potent corticosteroid that has a wide range of therapeutic applications, including the treatment of allergic reactions, inflammatory diseases, autoimmune disorders, and cancer. Dexamethasone is available in various forms, including tablets, injections, and inhalers, and is used to treat a variety of conditions, such as asthma, COPD, rheumatoid arthritis, lupus, multiple sclerosis, and inflammatory bowel disease. It is also used to treat severe cases of COVID-19, as it has been shown to reduce inflammation and improve outcomes in patients with severe illness. However, dexamethasone is a potent drug that can have significant side effects, including weight gain, fluid retention, high blood pressure, increased risk of infection, and mood changes. Therefore, it is typically prescribed only when other treatments have failed or when the potential benefits outweigh the risks.
In the medical field, a headache is a common symptom that can be described as a pain or discomfort in the head, neck, or scalp. Headaches can range in severity from mild to severe and can be acute (short-term) or chronic (long-term). There are many different types of headaches, including tension headaches, migraine headaches, cluster headaches, and sinus headaches. Each type of headache has its own set of characteristics and may be caused by different factors. Headaches can be caused by a variety of factors, including stress, dehydration, lack of sleep, eye strain, certain foods or drinks, hormonal changes, and medical conditions such as high blood pressure or meningitis. Diagnosis and treatment of headaches depend on the type of headache and the underlying cause. Treatment options may include medication, lifestyle changes, and other therapies.
Dimenhydrinate is a medication that is used to prevent and treat motion sickness. It works by blocking certain chemicals in the brain that are responsible for the symptoms of motion sickness, such as nausea, vomiting, and dizziness. Dimenhydrinate is available over-the-counter in the form of tablets, capsules, and liquids, and it is also available by prescription in higher doses. It is usually taken 30 to 60 minutes before exposure to motion that is likely to cause motion sickness. Dimenhydrinate may cause side effects such as drowsiness, dizziness, and dry mouth. It is not recommended for use in children under the age of 6 or in people with certain medical conditions, such as glaucoma or kidney disease.
Doxylamine is a medication that is primarily used to treat symptoms of allergies, colds, and the flu. It is also sometimes used to treat insomnia and nausea. Doxylamine is a sedative-hypnotic medication, which means that it can cause drowsiness and other side effects such as dizziness, dry mouth, and blurred vision. It is available over-the-counter in the United States and is usually taken as a tablet or liquid. Doxylamine is not recommended for use during pregnancy or breastfeeding, as it may harm the developing fetus or newborn.
Cyclizine is a medication that is used to treat motion sickness, nausea, and vomiting. It works by blocking the action of certain chemicals in the brain that can cause these symptoms. Cyclizine is available in tablet, syrup, and injection forms, and is usually taken before or during exposure to motion or other triggers that can cause nausea and vomiting. It is also sometimes used to treat vertigo, a condition that causes a spinning sensation. Cyclizine is generally well-tolerated, but can cause side effects such as drowsiness, dizziness, and dry mouth. It is important to follow the instructions of your healthcare provider when taking cyclizine, and to let them know if you experience any side effects.
Gastrointestinal (GI) diseases refer to conditions that affect the digestive system, which includes the esophagus, stomach, small intestine, large intestine, rectum, and anus. These diseases can range from minor to severe and can affect any part of the digestive system. Some common examples of gastrointestinal diseases include: 1. Gastroesophageal reflux disease (GERD): A condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms. 2. Peptic ulcers: Sores that develop in the lining of the stomach or duodenum, often caused by the bacteria Helicobacter pylori. 3. Inflammatory bowel disease (IBD): A group of chronic inflammatory conditions that affect the digestive tract, including Crohn's disease and ulcerative colitis. 4. Irritable bowel syndrome (IBS): A condition characterized by abdominal pain, bloating, and changes in bowel habits that are not related to a structural problem in the digestive system. 5. Celiac disease: An autoimmune disorder in which the body reacts to gluten, a protein found in wheat, barley, and rye. 6. Diverticulitis: An inflammation of small pouches in the wall of the colon. 7. Colorectal cancer: A type of cancer that starts in the colon or rectum. 8. Gastrointestinal infections: Infections caused by bacteria, viruses, or parasites that affect the digestive system. These are just a few examples of the many gastrointestinal diseases that can affect people. Treatment for these conditions can vary depending on the specific disease and its severity.
Morphine is a powerful opioid medication that is used to relieve severe pain. It is derived from the opium poppy and is one of the most potent naturally occurring opioids. Morphine works by binding to specific receptors in the brain and spinal cord, which can reduce the perception of pain and produce feelings of euphoria. It is often prescribed for patients who are experiencing severe pain, such as those with cancer or after surgery. Morphine can be administered in a variety of ways, including orally, intravenously, or through injection. It can also be used in combination with other medications to enhance its pain-relieving effects. However, morphine can also be highly addictive and can lead to dependence and withdrawal symptoms if used for an extended period of time. It is important for patients to use morphine only as directed by their healthcare provider and to avoid taking more than the recommended dose.
Abdominal pain is a common symptom that refers to discomfort or pain in the abdominal region, which includes the stomach, intestines, liver, gallbladder, pancreas, and other organs in the abdomen. It can be acute or chronic, and can range from mild to severe. In the medical field, abdominal pain is often evaluated based on its location, duration, severity, and associated symptoms. The location of the pain can help identify which organ or organ system may be causing the discomfort. For example, pain in the upper right quadrant of the abdomen may indicate a problem with the liver or gallbladder, while pain in the lower left quadrant may indicate a problem with the colon or appendix. The duration and severity of the pain can also provide important clues about the underlying cause. For example, sudden, severe abdominal pain may indicate a medical emergency, such as a ruptured appendix or a perforated ulcer. Associated symptoms, such as nausea, vomiting, diarrhea, constipation, bloating, or fever, can also help doctors diagnose the cause of abdominal pain. In some cases, further diagnostic tests, such as blood tests, imaging studies, or endoscopy, may be necessary to determine the underlying cause of the pain.
Fentanyl is a synthetic opioid pain medication that is approximately 100 times more potent than morphine. It is used to treat severe pain, such as that caused by cancer or after surgery. Fentanyl is available in a variety of forms, including tablets, lozenges, patches, and injections. It is also sometimes used in combination with other medications, such as hydromorphone or oxycodone, to increase their effectiveness. Fentanyl can be highly addictive and can cause respiratory depression, which can be life-threatening. It is important to use fentanyl only under the guidance of a healthcare professional and to follow their instructions carefully.
Fluorouracil is a chemotherapy drug that is commonly used to treat various types of cancer, including colorectal cancer, breast cancer, and head and neck cancer. It works by interfering with the production of DNA in cancer cells, which prevents them from dividing and growing. Fluorouracil is usually given intravenously or orally, and it can cause a range of side effects, including nausea, vomiting, diarrhea, and fatigue. In some cases, it can also cause more serious side effects, such as mouth sores, skin reactions, and anemia.
Quinolizines are a class of organic compounds that contain a six-membered ring with two nitrogen atoms. They are structurally related to quinolines, which have a similar ring structure but with only one nitrogen atom. Quinolizines have a wide range of biological activities and are used in the treatment of various medical conditions, including: 1. Antimalarial drugs: Quinolizines are used as antimalarial drugs, such as chloroquine and hydroxychloroquine, which are used to treat and prevent malaria. 2. Antipsychotic drugs: Quinolizines are also used as antipsychotic drugs, such as chlorpromazine and thioridazine, which are used to treat schizophrenia and other psychotic disorders. 3. Antihistamines: Quinolizines are used as antihistamines, such as astemizole and terfenadine, which are used to treat allergies and other conditions caused by histamine release. 4. Antifungal drugs: Quinolizines are used as antifungal drugs, such as ketoconazole and itraconazole, which are used to treat fungal infections. 5. Anticancer drugs: Quinolizines are also used as anticancer drugs, such as quinoline-8-carboxylic acid, which is being studied for its potential to treat various types of cancer. Overall, quinolizines have a diverse range of biological activities and are used in the treatment of various medical conditions.
In the medical field, fatigue is a common symptom that can be caused by a variety of factors, including physical or mental exertion, lack of sleep, chronic illness, or medication side effects. Fatigue is characterized by a persistent feeling of tiredness or exhaustion that is not relieved by rest or sleep. Fatigue can be a symptom of many different medical conditions, including anemia, chronic fatigue syndrome, fibromyalgia, heart disease, sleep disorders, and thyroid disorders. It can also be a side effect of certain medications, such as antidepressants or chemotherapy drugs. In some cases, fatigue may be a sign of a more serious underlying condition, such as cancer or a neurological disorder. It is important to discuss any persistent feelings of fatigue with a healthcare provider to determine the cause and appropriate treatment.
Promethazine is a medication that is used to treat a variety of conditions, including nausea and vomiting, allergies, and motion sickness. It is a type of antihistamine, which means that it works by blocking the action of histamine, a chemical that is produced by the body in response to allergens or other irritants. Promethazine can be taken orally in the form of tablets, capsules, or syrup, or it can be injected into a muscle or given intravenously. It is also sometimes used as a sedative or to treat insomnia. Promethazine can cause side effects such as drowsiness, dizziness, and dry mouth, and it should not be used by people who are allergic to it or who have certain medical conditions, such as glaucoma or prostate problems.
Leukopenia is a medical condition characterized by a low number of white blood cells (leukocytes) in the blood. The normal range of white blood cells in the blood is typically between 4,500 and 11,000 cells per microliter (µL) of blood. When the number of white blood cells falls below 4,000 cells/µL, it is considered leukopenia. Leukopenia can be caused by a variety of factors, including infections, autoimmune disorders, certain medications, radiation therapy, chemotherapy, and bone marrow disorders. It can also be a symptom of more serious underlying conditions, such as leukemia, lymphoma, or other blood disorders. Symptoms of leukopenia may include fatigue, weakness, fever, chills, and an increased susceptibility to infections. Treatment for leukopenia depends on the underlying cause and may include medications to stimulate the production of white blood cells, antibiotics to treat infections, or other therapies to address the underlying condition.
Nitrous oxide, also known as laughing gas, is a colorless, odorless gas that is commonly used in the medical field as an anesthetic and analgesic. It is a potent analgesic, meaning it can help to reduce pain and discomfort during medical procedures, and it is also a sedative, meaning it can help to calm and relax patients. In medical settings, nitrous oxide is typically administered through a mask that covers the patient's nose and mouth. The gas is mixed with oxygen and inhaled by the patient, which helps to produce a feeling of relaxation and euphoria. Nitrous oxide is often used in combination with other anesthetics, such as local anesthetics or general anesthesia, to provide a more complete and effective anesthetic. Nitrous oxide is considered to be a relatively safe anesthetic, with few side effects. However, it can cause dizziness, lightheadedness, and nausea in some patients, and it can also cause a temporary decrease in blood pressure. As with any anesthetic, it is important for patients to follow their doctor's instructions carefully and to report any side effects or concerns to their healthcare provider.
Deoxycytidine is a nucleoside that is a building block of DNA. It is composed of a deoxyribose sugar, a nitrogenous base (cytosine), and a phosphate group. Deoxycytidine is a key component of the nucleic acid chain that makes up DNA, and it plays a crucial role in the process of DNA replication. In the medical field, deoxycytidine is sometimes used as a medication to treat certain types of cancer, such as chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). It works by inhibiting the growth and division of cancer cells.
Dizziness is a common symptom that can be experienced by people of all ages and can have a variety of causes. In the medical field, dizziness is typically defined as a sensation of lightheadedness, unsteadiness, or spinning that can be caused by a variety of factors. There are several types of dizziness, including: 1. Vertigo: A type of dizziness that is characterized by a spinning sensation, usually accompanied by nausea and vomiting. 2. Lightheadedness: A feeling of weakness or faintness, often caused by low blood pressure or dehydration. 3. Syncope: A temporary loss of consciousness that can be caused by a variety of factors, including low blood pressure, heart problems, or anemia. 4. Benign Paroxysmal Positional Vertigo (BPPV): A type of vertigo that is caused by small crystals in the inner ear becoming dislodged and moving into the wrong position. 5. Meniere's Disease: A disorder of the inner ear that can cause vertigo, hearing loss, and ringing in the ears. Dizziness can be a symptom of a variety of medical conditions, including low blood pressure, dehydration, inner ear disorders, heart problems, and neurological disorders. If you are experiencing dizziness, it is important to speak with a healthcare provider to determine the underlying cause and receive appropriate treatment.
Pruritus is a medical term used to describe an intense, persistent, and often uncontrollable urge to scratch or rub a particular area of the skin. It is commonly referred to as "itching" and can be caused by a variety of factors, including skin conditions, infections, allergies, hormonal changes, and certain medications. Pruritus can be a symptom of many different medical conditions, such as eczema, psoriasis, liver disease, kidney disease, and cancer. It can also be a side effect of certain medications, such as antibiotics, antihistamines, and chemotherapy drugs. Treatment for pruritus depends on the underlying cause. In some cases, over-the-counter creams or ointments may be sufficient to relieve symptoms. In more severe cases, prescription medications or other treatments may be necessary. It is important to consult a healthcare professional if you are experiencing persistent or severe itching, as it could be a sign of an underlying medical condition that requires treatment.
Constipation is a common digestive disorder characterized by difficulty in passing stools or infrequent bowel movements. It is typically defined as having fewer than three bowel movements per week or difficulty passing stools that are hard, dry, and lumpy. Constipation can be caused by a variety of factors, including a lack of fiber in the diet, dehydration, certain medications, hormonal changes, and certain medical conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and Parkinson's disease. Symptoms of constipation may include abdominal pain, bloating, nausea, vomiting, and a feeling of incomplete bowel movements. Treatment for constipation typically involves changes in diet and lifestyle, such as increasing fiber intake and staying hydrated, as well as the use of over-the-counter laxatives or stool softeners. In severe cases, medical intervention may be necessary.
Anorexia is a mental health disorder characterized by an intense fear of gaining weight or becoming fat, leading to a distorted body image and a restrictive eating behavior. People with anorexia often have a significantly lower body weight than is considered healthy for their age, sex, and height. They may also engage in extreme behaviors such as purging (e.g., vomiting, using laxatives), excessive exercise, or fasting to try to lose weight or maintain their low body weight. Anorexia can have serious physical and mental health consequences, including malnutrition, electrolyte imbalances, heart problems, and depression or anxiety. Treatment typically involves a combination of psychotherapy, medical care, and nutritional counseling.
Neutropenia is a medical condition characterized by a low number of neutrophils, which are a type of white blood cell that plays a crucial role in the body's immune system. Neutrophils are responsible for fighting off infections and are a key component of the body's defense against bacterial, viral, and fungal infections. Neutropenia is typically defined as a neutrophil count of less than 1,500 cells per microliter (µL) of blood. However, the normal range of neutrophil counts can vary depending on the laboratory and the individual's age and sex. Neutropenia can be caused by a variety of factors, including certain medications, infections, autoimmune disorders, and cancer treatments such as chemotherapy and radiation therapy. It can also be a symptom of other medical conditions, such as bone marrow disorders, genetic disorders, and nutritional deficiencies. Neutropenia can increase the risk of infections, as the body has fewer neutrophils to fight off pathogens. Symptoms of neutropenia may include fever, chills, fatigue, and sore throat. Treatment for neutropenia depends on the underlying cause and may include medications to stimulate the production of neutrophils, antibiotics to treat infections, or changes to the individual's medications or treatment plan.
Sufentanil is a synthetic opioid analgesic that is used in medicine for the relief of severe pain. It is a potent and short-acting opioid, with a rapid onset and a relatively brief duration of action. Sufentanil is often used in anesthesia and intensive care medicine, as well as for the management of acute pain in the emergency department. It is available in a variety of forms, including intravenous injection, intramuscular injection, and transdermal patch. Sufentanil is a Schedule II controlled substance in the United States, meaning that it has a high potential for abuse and dependence.
Alopecia is a medical condition characterized by hair loss. It can affect both men and women and can be caused by a variety of factors, including genetics, hormonal changes, autoimmune disorders, infections, and certain medications. There are several types of alopecia, including: 1. Androgenetic alopecia: This is the most common type of hair loss, affecting both men and women. It is caused by genetics and hormonal changes. 2. Telogen effluvium: This type of hair loss occurs when there is an increase in the number of hair follicles in the resting phase, leading to shedding of hair. 3. Anagen effluvium: This type of hair loss occurs when there is damage to the hair follicles during the growth phase, leading to shedding of hair. 4. Scarring alopecia: This type of hair loss occurs when the hair follicles are damaged or destroyed, leading to permanent hair loss. 5. Alopecia areata: This is an autoimmune disorder that causes hair loss in patches on the scalp and other parts of the body. Treatment for alopecia depends on the type and severity of the condition. It may include medications, hair transplantation, and other therapies.
Postoperative complications are adverse events that occur after a surgical procedure. They can range from minor issues, such as bruising or discomfort, to more serious problems, such as infection, bleeding, or organ damage. Postoperative complications can occur for a variety of reasons, including surgical errors, anesthesia errors, infections, allergic reactions to medications, and underlying medical conditions. They can also be caused by factors such as poor nutrition, dehydration, and smoking. Postoperative complications can have serious consequences for patients, including prolonged hospital stays, additional surgeries, and even death. Therefore, it is important for healthcare providers to take steps to prevent postoperative complications and to promptly recognize and treat them if they do occur.
Receptors, Serotonin, 5-HT3 are a type of protein found on the surface of cells in the body that bind to the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). These receptors are classified as G-protein coupled receptors and are involved in a variety of physiological processes, including nausea, vomiting, and pain perception. The 5-HT3 receptor is primarily expressed in the gastrointestinal tract, where it plays a role in regulating the movement of food through the digestive system. Activation of 5-HT3 receptors by serotonin can cause smooth muscle contractions, leading to nausea and vomiting. 5-HT3 receptors are also found in the brain, where they are involved in regulating mood, anxiety, and pain perception. In the medical field, 5-HT3 receptors are targeted by a class of drugs called 5-HT3 receptor antagonists, which are used to treat nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. These drugs work by blocking the action of serotonin at 5-HT3 receptors, thereby preventing the stimulation of smooth muscle contractions and reducing nausea and vomiting. 5-HT3 receptor antagonists are also used to treat irritable bowel syndrome and other gastrointestinal disorders.
Piperidines are a class of organic compounds that contain a six-membered ring with nitrogen atoms at positions 1 and 4. They are commonly used in the pharmaceutical industry as a building block for the synthesis of a wide range of drugs, including analgesics, anti-inflammatory agents, and antihistamines. Piperidines are also found in natural products, such as alkaloids, and have been used in traditional medicine for their various therapeutic effects. In the medical field, piperidines are often used as a starting point for the development of new drugs, as they can be easily modified to produce a wide range of pharmacological activities.
Camptothecin is a natural alkaloid compound that is derived from the Chinese tree Camptotheca acuminata. It has been used in the medical field as an anti-cancer drug due to its ability to inhibit the activity of topoisomerase I, an enzyme that is essential for DNA replication and repair. This inhibition leads to the formation of DNA double-strand breaks, which can cause cell death and prevent the growth and spread of cancer cells. Camptothecin and its derivatives have been used to treat various types of cancer, including ovarian, lung, and colorectal cancer. However, they can also cause significant side effects, such as nausea, vomiting, and diarrhea, and may interact with other medications.
Diarrhea is a medical condition characterized by the passage of loose, watery stools more than three times a day. It can be acute, meaning it lasts for a short period of time, or chronic, meaning it persists for more than four weeks. Diarrhea can be caused by a variety of factors, including infections, food poisoning, medications, underlying medical conditions, and stress. It can also be a symptom of other medical conditions, such as inflammatory bowel disease, celiac disease, and irritable bowel syndrome. Diarrhea can cause dehydration, electrolyte imbalances, and malnutrition if it persists for an extended period of time. Treatment for diarrhea depends on the underlying cause and may include medications, dietary changes, and fluid replacement therapy. In severe cases, hospitalization may be necessary.
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Chemotherapy-induced nausea and vomiting
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- When do I need to see a health care provider for nausea and vomiting? (medlineplus.gov)
- How is the cause of nausea and vomiting diagnosed? (medlineplus.gov)
- Treatments for nausea and vomiting depend on the cause. (medlineplus.gov)
- There are some medicines that can treatment nausea and vomiting. (medlineplus.gov)
- Gastrointestinal (GI) disorders represent some of the most frequent complaints during pregnancy, possibly due in part to elevated levels of progesterone (eg, nausea/vomiting, gastroesophagel reflux disease [GERD]) and/or prostaglandins (diarrhea). (medscape.com)
- Persistence of nausea and vomiting into the second or third semester should prompt a search for other causes. (medscape.com)
- Pyridoxine (vitamin B-6) is an alternative therapeutic agent in patients with severe nausea or vomiting. (medscape.com)
- In fact, women with mild nausea and vomiting in pregnancy appear to have better pregnancy outcomes compared with women without these symptoms. (medscape.com)
- Hyperemesis gravidarum occurs in 3 to 10 cases per 1000 pregnancies and is characterized by intractable nausea and vomiting that occurs in early pregnancy, leading to fluid and electrolyte imbalances. (medscape.com)
- Nausea and vomiting can accompany digestive conditions and infections as well as conditions such as labyrinthitis or headache . (medicinenet.com)
- Your oncology care providers now have many ways to prevent and ease nausea and vomiting from chemotherapy. (cancercare.org)
- Surveys have shown that many patients and their loved ones believe nausea and vomiting occur with all types of chemotherapy (anti-cancer drugs). (cancercare.org)
- Though many people receiving chemotherapy may still experience nausea and vomiting, your health care team has many ways to both prevent and ease these symptoms. (cancercare.org)
- Do not accept nausea and vomiting as "the norm," as there are many medications available to relieve your symptoms. (cancercare.org)
- When nausea or vomiting becomes severe, it can cause dehydration. (cancercare.org)
- Several naturally occurring protein transmitters, including ones called serotonin and substance P, are released, triggering the nausea and vomiting reflex. (cancercare.org)
- Some anti-cancer drugs can irritate these areas, leading to nausea and vomiting. (cancercare.org)
- Some people experience nausea and vomiting within the first few hours of receiving chemotherapy (known as an acute reaction). (cancercare.org)
- Others don't feel symptoms the day of chemotherapy but develop nausea and vomiting during the following few days (a delayed reaction). (cancercare.org)
- Cancer treatments, such as chemotherapy or radiation therapy can cause nausea and vomiting. (cancer.org)
- Some other drugs, such as targeted therapy and immunotherapy can cause nausea and vomiting too. (cancer.org)
- Some can make you have nausea and/or vomiting while others might not. (cancer.org)
- Sometimes the type of cancer you have can make you have nausea and vomiting too. (cancer.org)
- How likely you are to have nausea and vomiting while getting treatment depends on many things. (cancer.org)
- Drugs that travel through the body are more likely to cause nausea and vomiting than treatment that only affects one area of the body, such as radiation therapy. (cancer.org)
- For example, if doses of a chemo drug that causes nausea and vomiting are given close together, there's less time for the person to recover from the effects of the last dose before the next one is given. (cancer.org)
- For instance, chemo given through a vein (intravenous, or by IV) may cause nausea and vomiting much faster than a drug given by mouth. (cancer.org)
- Having a tumor in the brain, liver, or gastrointestinal tract may increase the risk for nausea and vomiting. (cancer.org)
- Other drugs (such as pain medicines) that may cause or worsen nausea and/or vomiting. (cancer.org)
- There's no way to know for sure if you will have nausea and vomiting, but your doctor will consider these things when choosing anti-nausea and vomiting medicines to use with your cancer treatment. (cancer.org)
- If you're getting a drug to treat cancer, be sure to talk to your cancer care team about what kind of drug it is and how likely it is to cause nausea and vomiting. (cancer.org)
- NEW ORLEANS -- There was no benefit to giving patients supplemental oxygen during surgery to reduce postoperative nausea and vomiting (PONV), according to a post hoc analysis of a randomized trial. (medpagetoday.com)
- Elevated levels of progesterone may lead to alterations in gastrointestinal motility which could contribute to nausea, vomiting, and/or GERD. (nih.gov)
- Postoperative nausea and vomiting are common complications of anaesthesia. (who.int)
- This double-blind clinical trial assessed the incidence of nausea and vomiting after cataract surgery with intravenous anaesthesia in 100 patients randomly assigned to preinduction placebo (saline), metoclopramide (10 mg), dexamethasone (8 mg) or the 2 drugs combined. (who.int)
- Metoclopramide plus dexamethasone combination significantly decreased nausea and vomiting both in the recovery room and 24 hours afterwards and is recommended for high-risk groups, especially in outpatient surgeries. (who.int)
- Vomiting empties the stomach and often makes people with nausea feel considerably better, at least temporarily. (msdmanuals.com)
- This entry was posted on Monday, October 15th, 2012 at 12:43 AM and is filed under Marijuana (Cannabinoids) , Nausea/Vomiting . (thecamreport.com)
- Prevention of chemotherapy-induced nausea and vomiting (CINV) is crucial in maximizing patients' quality of life and optimizing outcomes of cancer therapy, and can be done more effectively than ever before. (medscape.com)
- Similar to realtors' mantra of "location, location, location," oncology nurses should have the mantra "prevention, prevention, prevention" foremost on their minds when assessing and developing a plan of care for controlling chemotherapy-induced nausea and vomiting (CINV). (medscape.com)
- According to the National Comprehensive Cancer Network (NCCN, 2012a), prevention of nausea and vomiting is the primary goal of antiemetic treatment for all patients receiving cancer therapy. (medscape.com)
- Patients who experience nausea or vomiting despite the use of prophylactic antiemetics frequently require additional medications, hydration, and sometimes hospitalization. (medscape.com)
- Poorly controlled nausea or vomiting associated with chemotherapy increases risk of developing anticipatory nausea and vomiting, which ranges from 18%-57% in incidence (NCCN, 2012a). (medscape.com)
- The primary strategy in treating anticipatory nausea and vomiting is prevention through the consistent use of optimal antiemetic therapy beginning with the initial cycle of treatment (NCCN, 2012a). (medscape.com)
- A study of patients with breast cancer who received aggressive antiemetics demonstrated improved appetite, better control of nausea and vomiting, and subsequent improved quality of life (Roldán et al. (medscape.com)
- 2005). Management of symptoms, including nausea and vomiting, is crucial to preventing delays in treatment related to dehydration or hospitalizations. (medscape.com)
- Nausea and vomiting (N/V) is a common complication of cancer treatment and a common cause of anxiety and distress in patients, in some cases even prior to their first chemotherapy session. (medscape.com)
- The NCCN, MASCC/ESMO, and ASCO guidelines include management recommendations for both chemotherapy-induced nausea and vomiting (CINV) and radiation-induced nausea and vomiting (RINV). (medscape.com)
- To answer, acid reflux can cause nausea and vomiting. (novabariatrics.com)
- These receptors are responsible for regulating nausea and vomiting. (getyouridcard.com)
- When THC binds to the CB1 receptors, it activates them and reduces the signals that are sent to the brain that trigger nausea and vomiting. (getyouridcard.com)
- This is why marijuana is often recommended for individuals who are undergoing chemotherapy, as it can help to reduce the nausea and vomiting that are often associated with this type of treatment. (getyouridcard.com)
- This strain is often recommended for individuals who experience nausea and vomiting, as well as those who suffer from anxiety and chronic pain. (getyouridcard.com)
- In addition to its ability to reduce nausea and vomiting, THC is also known to have anti-inflammatory and analgesic properties. (getyouridcard.com)
- Marijuana can be a helpful tool for individuals who suffer from nausea and vomiting. (getyouridcard.com)
- Blisslets provide fast relief from nausea and vomiting without drugs or side effects. (blisslets.com)
- It is very important to prevent and control nausea and vomiting in patients receiving chemotherapy. (navigatingcare.com)
- Uncontrolled nausea and vomiting can interfere with your ability to receive cancer treatment and care for yourself. (navigatingcare.com)
- If you have had a prior "bad" experience with nausea and vomiting, please let your nurse or doctor know, as they may be able to prescribe a medication that will enable you to relax a little and prevent the "anticipatory" nausea and vomiting. (navigatingcare.com)
- Writing down the time and frequency of any nausea and vomiting episodes can help your healthcare provider assess your anti-nausea regimen and make the appropriate changes to better control your symptoms. (navigatingcare.com)
- If you experienced many episodes of nausea and vomiting, changes in your medications can be made. (navigatingcare.com)
- You are unable to take your anti-nausea medication or you are vomiting up the medicine. (navigatingcare.com)
- Multiple-day administration of fosaprepitant combined with tropisetron and olanzapine improves the prevention of nausea and vomiting in patients receiving chemotherapy prior to autologous hematopoietic stem cell transplant: a retrospective study. (bvsalud.org)
- Chemotherapy -induced nausea and vomiting (CINV) is common in patients with lymphoma and multiple myeloma (MM) receiving high- dose chemotherapy (HDC) followed by autologous stem cell transplantation (ASCT). (bvsalud.org)
- The severity of symptoms dictates the approach to therapy in a pregnant patient with nausea. (medscape.com)
- In addition to severe head pain, migraine can cause symptoms such as dizziness, nausea , or vision changes. (healthline.com)
- It is a natural remedy that many people find helpful for managing nausea symptoms. (chesbrewco.com)
- Whether you're experiencing nausea due to pregnancy symptoms or other causes like chemotherapy or flu, sipping on herbal teas may provide some relief without the need for medication. (chesbrewco.com)
- Acupressure may provide relief of nausea symptoms but does not cure underlying causes. (blisslets.com)
- That's especially crucial if you are receiving chemotherapy in pill form, as you will need to take the chemotherapy and the anti-nausea drugs in a certain order and at a certain time of day. (cancercare.org)
- Ginger tea is particularly known for its anti-nausea properties, while peppermint tea can help ease digestive discomfort. (chesbrewco.com)
Effective in curbin1
- Some people find aromatherapy to be both emotionally calming and effective in curbing nausea. (dignityhealth.org)
Incidence of nausea1
- The incidence of nausea in the recovery room was 44% with placebo, 20% with metoclopramide, 16% with dexamethasone and 8% with the combination. (who.int)
- Can Acid Reflux Cause Nausea? (novabariatrics.com)
Contribute to nausea1
- Other than this, GERD or acid reflux also causes indigestion and heartburn, which can contribute to nausea. (novabariatrics.com)
- The idea behind using baking soda to alleviate nausea is that it can help neutralize stomach acid and soothe the digestive system. (chesbrewco.com)
- Look at the cbd gummies for nausea from chemo appearance of these'heroes' Li Haoyu said with a chuckle These girls are really good at cheating, as long as they give. (amarprice.com)
- cbd gummies for nausea from chemo So Li Haoyu immediately said sincerely and calmly without thinking My Mao and Yun Bao Believe it or not, I have the two of you by my side. (amarprice.com)
- Seeing the excited Haha, cbd gummies for nausea from chemo everyone would smile heartily, but at this time, Lee Kwang Soo suddenly said to Ji Hyo Just kidding, of course, except for Haoyu, who is closest to my sister's ideal type! (amarprice.com)
- Looking at the shocked Liu Jae-shik, cbd gummies for nausea from chemo Li Haoyu suddenly smiled and said, Look, it scares you Although you say you have no position, in fact, I think you are the same as jyl and those guys. (amarprice.com)
- However, it was too late, because everyone saw it, and Liu Zaishi walked up to Li Haoyu jealously cbd gummies for nausea from chemo and angrily, grabbed Li Haoyu's collar and said Ah, are you the patron saint of Girls' Generation? (amarprice.com)
- I hope you uncles, give Haoyu a cbd gummies for nausea from chemo face, and don't join forces with the Zheng family, otherwise Haoyu will only have a bloodthirsty blow! (amarprice.com)
- Nausea is an unpleasant feeling of needing to vomit. (msdmanuals.com)
- Nausea is when you feel sick to your stomach, as if you are going to throw up. (medlineplus.gov)
- That feeling in your stomach can be the first sign of nausea, which can be treated with various types of medications. (cancercare.org)
- Regurgitation and Rumination Regurgitation is the spitting up of food from the esophagus or stomach without nausea or forceful contractions of the abdominal muscles. (msdmanuals.com)
- which is the spitting up of stomach contents without forceful abdominal contractions or nausea. (msdmanuals.com)
- Eat small meals frequently, as nausea and acid reflux can occur on an empty stomach. (novabariatrics.com)
- One of its many medicinal benefits is its ability to help calm the stomach and reduce nausea. (getyouridcard.com)
- In this article, we will explore five strains of marijuana known to help calm the stomach and how THC works in the body to help with nausea. (getyouridcard.com)
- However, this strain is also known to help calm the stomach and reduce nausea. (getyouridcard.com)
- ACDC, Sour Diesel, Blue Dream, Bubba Kush, and Harlequin are just a few of the strains of marijuana that are known to help calm the stomach and reduce nausea. (getyouridcard.com)
- Nausea is often referred to as a feeling of queasiness around the stomach or abdominal area. (indygastro.com)
- This area is not big, and this are CBD gummies legal in texas area cbd gummy bears for nausea is completely isolated by surveillance cameras, unless Gabriel is hidden in this area Otherwise, once Gabriel is listed, it will definitely be discovered by surveillance cameras. (tiktaalik-music.com)
- Nausea is a common discomfort that can throw off your entire day, with many individuals constantly searching for an effective remedy. (chesbrewco.com)
- This article delves into the science and anecdotes behind Pepsi's alleged nausea-relieving properties to provide readers with all the information they need on this unusual remedy. (chesbrewco.com)
- An added bonus is that cold water is generally easy to consume even when feeling unwell, making it an accessible and uncomplicated remedy for those suffering from alcohol-related nausea. (chesbrewco.com)
- Soda, particularly clear sodas like ginger ale and lemon-lime carbonated beverages, has long been used as a remedy for nausea. (chesbrewco.com)
- One potential remedy for nausea is a baking soda brew. (chesbrewco.com)
- Herbal teas can be a natural and soothing remedy for nausea. (chesbrewco.com)
- Acupressure bracelets are a proven nausea remedy, but who says they can't also be stylish? (blisslets.com)
- Nausea is a symptom often associated with acid reflux. (novabariatrics.com)
- The patient complains of recurring headaches and nausea that started approximately 1 to 2 weeks ago and of recent angina attacks. (cdc.gov)
- Nausea is often referred to as a queasy feeling in the abdominal region. (indygastro.com)
- Cette étude clinique en double aveugle évaluait l'incidence des nausées et des vomissements après une chirurgie de la cataracte avec anesthésie par voie intraveineuse chez 100 patients auxquels un placebo (eau saline), du métoclopramide (10 mg), de la dexaméthasone (8 mg) ou les deux médicaments associés avaient été administrés de manière randomisée avant l'opération. (who.int)
- L'association du métoclopramide et de la dexaméthasone a considérablement réduit les nausées et vomissements, non seulement en salle de réveil mais également dans les 24 heures qui suivent, et est recommandée pour les groupes à haut risque, notamment pour les patients opérés en ambulatoire. (who.int)
- They routinely address nausea in Indianapolis, IN patients and have the training and the skills needed to allow you to return to a healthier quality of life. (indygastro.com)
- Some patients have found herbal teas such as ginger or chamomile, ginger ale or the use of lavender in a pillow helps decrease their nausea prior to and during their therapy. (navigatingcare.com)
- Additionally, the sugary content in soda provides a quick source of energy that may help alleviate feelings of fatigue that often accompany nausea. (chesbrewco.com)
- Both options offer a refreshing way to alleviate nausea without relying on medications or other remedies. (chesbrewco.com)
- This strain is often recommended for individuals who suffer from chronic pain, anxiety, and nausea. (getyouridcard.com)
- Receiving the treatment required for nausea doesn't have to be difficult. (indygastro.com)
- The efficacy of acupuncture in relieving pain and nausea, for instance, has been conclusively demonstrated and is now acknowledged worldwide. (who.int)
- Coupled with frequent coughing and burping, the sour taste leads to nausea. (novabariatrics.com)
- Nausea tends to recur in subsequent pregnancies, although it may be shorter in duration. (medscape.com)
- Nausea is a common indicator of various conditions. (indygastro.com)
- When enjoying ginger ale or ginger tea for nausea relief, it's important to choose brands that contain real ginger and minimal added sugars or artificial ingredients. (chesbrewco.com)