Nasal Mucosa
Nasal Polyps
Turbinates
Rhinitis, Allergic, Perennial
Nasal Lavage Fluid
Intestinal Mucosa
Gastric Mucosa
Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.
Nasal Septum
Nose
Mouth Mucosa
Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
Nasal Decongestants
Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)
Sneezing
Nasal Provocation Tests
Rhinitis, Allergic, Seasonal
Olfactory Mucosa
Nasal Cavity
Nasal Obstruction
Toluene 2,4-Diisocyanate
Ethmoid Bone
Rhinomanometry
Nasal Bone
Paranasal Sinuses
Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.
Rhinitis, Atrophic
Mucous Membrane
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
Anti-Allergic Agents
Allergens
Nitrosamines
Nasal Cartilages
Trigeminal Nerve
The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.
Histamine
Immunohistochemistry
Glycoconjugates
Respiratory System
Asthma, Aspirin-Induced
Eosinophils
Epithelium
Rhinometry, Acoustic
Biopsy
Rhinitis, Vasomotor
Erythema Multiforme
Airway Resistance
Histocytochemistry
Endoscopy
Procedures of applying ENDOSCOPES for disease diagnosis and treatment. Endoscopy involves passing an optical instrument through a small incision in the skin i.e., percutaneous; or through a natural orifice and along natural body pathways such as the digestive tract; and/or through an incision in the wall of a tubular structure or organ, i.e. transluminal, to examine or perform surgery on the interior parts of the body.
Aerosols
Immunoglobulin E
Eosinophil Granule Proteins
Bordetella
Irritants
Drugs that act locally on cutaneous or mucosal surfaces to produce inflammation; those that cause redness due to hyperemia are rubefacients; those that raise blisters are vesicants and those that penetrate sebaceous glands and cause abscesses are pustulants; tear gases and mustard gases are also irritants.
Nasal Lavage
Common Cold
Carnivora
Phosphorothioate Oligonucleotides
Histamine H1 Antagonists
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Mucociliary Clearance
Leishmaniasis, Mucocutaneous
A disease characterized by the chronic, progressive spread of lesions from New World cutaneous leishmaniasis caused by species of the L. braziliensis complex to the nasal, pharyngeal, and buccal mucosa some time after the appearance of the initial cutaneous lesion. Nasal obstruction and epistaxis are frequent presenting symptoms.
Zonula occludens toxin is a powerful mucosal adjuvant for intranasally delivered antigens. (1/1918)
Zonula occludens toxin (Zot) is produced by toxigenic strains of Vibrio cholerae and has the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through the mucosal barrier. In the present study, we investigated whether Zot could be exploited to deliver soluble antigens through the nasal mucosa for the induction of antigen-specific systemic and mucosal immune responses. Intranasal immunization of mice with ovalbumin (Ova) and recombinant Zot, either fused to the maltose-binding protein (MBP-Zot) or with a hexahistidine tag (His-Zot), induced anti-Ova serum immunoglobulin G (IgG) titers that were approximately 40-fold higher than those induced by immunization with antigen alone. Interestingly, Zot also stimulated high anti-Ova IgA titers in serum, as well as in vaginal and intestinal secretions. A comparison with Escherichia coli heat-labile enterotoxin (LT) revealed that the adjuvant activity of Zot was only sevenfold lower than that of LT. Moreover, Zot and LT induced similar patterns of Ova-specific IgG subclasses. The subtypes IgG1, IgG2a, and IgG2b were all stimulated, with a predominance of IgG1 and IgG2b. In conclusion, our results highlight Zot as a novel potent mucosal adjuvant of microbial origin. (+info)Morphology of intraepithelial corpuscular nerve endings in the nasal respiratory mucosa of the dog. (2/1918)
Corpuscular nerve endings in the nasal respiratory mucosa of the dog were investigated by immunohistochemical staining specific for protein gene product 9.5 by light and electron microscopy. In the nasal respiratory mucosa, complex corpuscular endings, which displayed bulbous, laminar and varicose expansions, were distributed on the dorsal elevated part of the nasal septum and on the dorsal nasal concha. The endings were 300-500 microm long and 100-250 microm wide. Some axons gave rise to a single ending while others branched into 2 endings. Cryostat sections revealed that the corpuscular endings were located within the nasal respiratory epithelium. On electron microscopy, immunoreactive nerve terminals that contained organelles, including mitochondria and neurofilaments, were observed within the epithelial layer near the lumen of the nasal cavity. Some terminals contacted the goblet cell. Such terminal regions were covered by the cytoplasmic process of ciliated cells and were never exposed to the lumen of the nasal cavity. These nerve endings are probably activated by pressure changes. (+info)Trigeminal and carotid body inputs controlling vascular resistance in muscle during post-contraction hyperaemia in cats. (3/1918)
1. In anaesthetized cats, the effects of stimulation of the receptors in the nasal mucosa and carotid body chemoreceptors on vascular resistance in hindlimb skeletal muscle were studied to see whether the responses were the same in active as in resting muscle. The measurements of vascular resistance were taken, first, in resting muscle, and second, in the immediate post-contraction hyperaemic phase that followed a 30 s period of isometric contractions. 2. Stimulation of the receptors in the nasal mucosa caused reflex apnoea and vasoconstriction in muscle. The latter response was attenuated when the test was repeated during post-contraction hyperaemia. 3. Stimulations of the carotid bodies were made during a period of apnoea evoked reflexly by electrical stimulation of both superior laryngeal nerves. This apnoea prevented any effects of changes in respiration on the carotid body reflex vascular responses. Stimulation of the carotid bodies evoked hindlimb muscle vasoconstriction. In the post-contraction hyperaemic period, the response was reduced or abolished. A similar attenuation of the reflex vasoconstrictor responses occurred in decentralized muscles stimulated through their motor roots in the cauda equina. 4. Evidence is presented that the attenuation of the vasoconstrictor responses evoked by the two reflexes is a phenomenon localized to the contracting muscles themselves resulting from an interaction between sympathetic neuronal activity and the local production of metabolites. 5. The results are discussed in relation to the metabolic needs of tissues in relation to asphyxial defence mechanisms such as occur in the diving response. (+info)Immunoglobulin-specific radioimmunoprecipitation assays for quantitation of nasal secretory antibodies to hemagglutinin of type A influenza viruses. (4/1918)
Radioimmunoprecipitation (RIP) assays were developed to selectively quantitate class-specific antibodies to purified hemagglutinins (HA) of type A influenza virus in nasal secretions. Rabbit anti-human secretory piece of immunoglobulin A (IgA) and rabbit anti-human IgG were used as second antibodies. A third antibody, goat anti-rabbit IgG, was incorporated into the system to separate immune complexes formed between iodinated HA, nasal wash test specimen, and second antibody. The utilization of this reagent avoided the need for large quantities of IgA and IgG antibody-negative carrier secretions. Nasal was specimens obtained from 14 adults immunized with an inactivated type A influenza virus vaccine were evaluated by RIP and viral neutralization assays. Significant homologous postvaccination secretory IgA and IgG antibody levels were demonstrable in 13 (93%) of individuals by RIP, whereas only 5 (36%) exhibited rises by viral neutralization tests. Moreover, the geometric mean IgA and IgG antibody levels were at least 20- and 37-fold greater than the neutralizing antibody titer. The pattern of heterologous immunoglobulin-specific antibody responses tended to be similar to those observed with the homologous HA subunit. (+info)Glycoconjugate expression in follicle-associated epithelium (FAE) covering the nasal-associated lymphoid tissue (NALT) in specific pathogen-free and conventional rats. (5/1918)
We examined lectin-histochemically the glycoconjugate expression in the follicle-associated epithelium (FAE) covering the nasal-associated lymphoid tissue (NALT) in the rat under specific pathogen-free (SPF) and conventional (CV) conditions and compared the results for SPF and CV rats as well as for membranous (M) cells and adjacent ciliated respiratory epithelial (CRE) cells in FAE. N-acetylgalactosamine-specific lectins, Dolichos biflorus (DBA), Helix pomatia (HPA), Glycine max (SBA) and Vicia villosa (VVA), and alpha-L-fucose-specific lectin, Ulex europaeus (UEA-I), preferentially bound to M cells mainly in the luminal surface compared with CRE cells in SPF rats, whereas DBA and UEA-I showed signs of preferential binding to the apical and basolateral cytoplasm as well as to the luminal surface of M cells in CV rats. In addition, HPA, SBA and VVA more frequently and extensively labeled M cells than CRE cells in CV rats with the same subcellular staining pattern as DBA and UEA-I. On the whole, the changes in lectin binding frequency and strength were more prominent in M cells than in CRE cells in both SPF and CV rats. The present results indicate that DBA and UEA-I are useful as markers of M cells in NALT. Furthermore, the pattern of expression of carbohydrate residues recognized by such lectins in SPF and CV rats suggests that M cells are highly sensitive to environmental changes. (+info)Anatomical structure and surface epithelial distribution in the nasal cavity of the common cotton-eared marmoset (Callithrix jacchus). (6/1918)
To validate use of the common cotton-eared marmoset (Callithrix jacchus) in inhalation toxicity studies, its nasal morphology was examined. The nasal turbinates each consisted of one maxilloturbinate and one ethmoturbinate: these were more planar in structure than the comparable structures of rodents or dogs. The nasal cavity epithelia comprised squamous epithelium (SE), nasal transitional epithelium (NTE), respiratory epithelium (RE) and olfactory epithelium (OE), listed in order of occurrence from anterior to posterior positions. NTE was distributed as a narrow band lying between SE and RE. OE was limited to the dorsal part of the cavity, which was structurally similar to that of the macaque or man. Overall, this study revealed structural the similarity of the whole nasal cavity in the marmoset to that of macaques or humans. Prediction of nasal cavity changes in man based on extrapolation from experimentally induced changes in the common marmoset therefore seems likely to be feasible, making it a useful animal model for inhalation studies. (+info)Nitric oxide-mediated regulation of transepithelial sodium and chloride transport in murine nasal epithelium. (7/1918)
Transepithelial ion transport is regulated by a variety of cellular factors. In light of recent evidence that nitric oxide (NO) production is decreased in cystic fibrosis airways, we examined the role of NO in regulating sodium and chloride transport in murine nasal epithelium. Acute intervention with the inducible NO synthase (iNOS)-selective inhibitor S-methylisothiourea resulted in an increase of amiloride-sensitive sodium absorption observed as a hyperpolarization of nasal transepithelial potential difference. Inhibition of iNOS expression with dexamethasone also hyperpolarized transepithelial potential difference, but only a portion of this increase proved to be amiloride sensitive. Chloride secretion was significantly inhibited in C57BL/6J mice by the addition of both S-methylisothiourea and dexamethasone. Mice lacking iNOS expression [NOS2(-/-)] also had a decreased chloride-secretory response compared with control mice. These data suggest that constitutive NO production likely plays some role in the downregulation of sodium absorption and leads to an increase in transepithelial chloride secretion. (+info)The rostral ventrolateral medulla mediates the sympathoactivation produced by chemical stimulation of the rat nasal mucosa. (8/1918)
1. We sought to outline the brainstem circuit responsible for the increase in sympathetic tone caused by chemical stimulation of the nasal passages with ammonia vapour. Experiments were performed in alpha-chloralose-anaesthetized, paralysed and artificially ventilated rats. 2. Stimulation of the nasal mucosa increased splanchnic sympathetic nerve discharge (SND), elevated arterial blood pressure (ABP), raised heart rate slightly and inhibited phrenic nerve discharge. 3. Bilateral injections of the broad-spectrum excitatory amino acid receptor antagonist kynurenate (Kyn) into the rostral part of the ventrolateral medulla (RVLM; rostral C1 area) greatly reduced the effects of nasal mucosa stimulation on SND (-80 %). These injections had no effect on resting ABP, resting SND or the sympathetic baroreflex. 4. Bilateral injections of Kyn into the ventrolateral medulla at the level of the obex (caudal C1 area) or into the nucleus tractus solitarii (NTS) greatly attenuated the baroreflex and significantly increased the baseline levels of both SND and ABP. However they did not reduce the effect of nasal mucosa stimulation on SND. 5. Single-unit recordings were made from 39 putative sympathoexcitatory neurons within the rostral C1 area. Most neurons (24 of 39) were activated by nasal mucosa stimulation (+65.8 % rise in discharge rate). Responding neurons had a wide range of conduction velocities and included slow-conducting neurons identified previously as C1 cells. The remaining putative sympathoexcitatory neurons were either unaffected (n = 8 neurons) or inhibited (n = 7) during nasal stimulation. We also recorded from ten respiratory-related neurons, all of which were silenced by nasal stimulation. 6. In conclusion, the sympathoexcitatory response to nasal stimulation is largely due to activation of bulbospinal presympathetic neurons within the RVLM. We suggest that these neurons receive convergent and directionally opposite polysynaptic inputs from arterial baroreceptors and trigeminal afferents. These inputs are integrated within the rostral C1 area as opposed to the NTS or the caudal C1 area. (+info)
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Nasal epithelial cells as a novel diagnostic approach for Cystic Fibrosis and CFTR relate | PostDoc Journal
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Semax drops nasal 0.1% 3 ml - WMFHI store
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Detection of DNA damage in gastric, colonic and nasal mucosa cells derived from the rat and from human biopsie specimens
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Prednisone bleeding
Pneumonia
Septal nasal cartilage
The septal nasal cartilage, (cartilage of the septum or quadrangular cartilage) is composed of hyaline cartilage.[1] It is ... Septal nasal cartilage. Bones and cartilages of septum of nose. Right side (cartilage of the septum visible as blue structure ... Its anterior margin, thickest above, is connected with the nasal bones, and is continuous with the anterior margins of the ... Anatomy figure: 33:02-01 at Human Anatomy Online, SUNY Downstate Medical Center - "Diagram of skeleton of medial (septal) nasal ...
Nasal meatus
A nasal meatus is a nasal passage of the nasal cavity, of which there are three; the superior meatus, middle meatus and ... The nasal meatuses are located beneath each of the corresponding nasal conchae. In the case where a fourth, supreme nasal ... It lies below the inferior concha and above the nasal cavity. It extends most of the length of the nasal cavity's lateral wall ... These nasal meatuses are also known as meatus nasi superior, meatus nasi medius, and meatus nasi inferior. (A meatus is a ...
Congenital afibrinogenemia
Nasal and oral mucosa bleeds. *Gastrointestinal bleeding. *Excessive/spontaneous bleeding or bruising from minor injury ...
Halostachine
The drug was also astringent on nasal mucosa. In man, an oral dose of 50 mg produced no effects on blood pressure. Later ...
Nepetalactone
... s affect domestic cats via nasal mucosa. Oral ingestion has no effects. They induce noticeable behavioral effects ...
Beta-defensin 2
Meyer JE, Harder J, Görögh T, Schröder JM, Maune S (July 2000). "[hBD-2 gene expression in nasal mucosa]". Laryngo- Rhino- ... "Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands". Infection and Immunity. 67 (6): ... "Production of beta-defensin antimicrobial peptides by maxillary sinus mucosa". American Journal of Rhinology. 15 (3): 175-179. ... "Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization". Nature. 465 (7296): ...
Corticosteroid
For nasal mucosa, sinuses, bronchi, and lungs. This group includes: Flunisolide Fluticasone furoate Fluticasone propionate ... A variety of steroid medications, from anti-allergy nasal sprays (Nasonex, Flonase) to topical skin creams, to eye drops ( ... Allergic rhinitis Atopic dermatitis Hives Angioedema Anaphylaxis Food allergies Drug allergies Nasal polyps Hypersensitivity ...
Nosebleed
... s are due to the rupture of a blood vessel within the richly perfused nasal mucosa. Rupture may be spontaneous or ... There are two types of nasal packing, anterior nasal packing and posterior nasal packing.[12] There are a number of different ... Spontaneous epistaxis is more common in the elderly as the nasal mucosa (lining) becomes dry and thin and blood pressure tends ... Application of a topical antibiotic ointment to the nasal mucosa has been shown to be an effective treatment for recurrent ...
CA12
"Gene expression for carbonic anhydrase isoenzymes in human nasal mucosa". Chem. Senses. 28 (7): 621-629. doi:10.1093/chemse/ ... in normal mucosa of large intestine and in colorectal tumors". Dig. Dis. Sci. 46 (10): 2179-2186. doi:10.1023/A:1011910931210. ... Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa ...
Polyp (medicine)
Nasal polyps[edit]. Main article: Nasal polyp. Nasal polyps are polypoidal masses arising mainly from the mucous membranes of ... Variable; classical mildly fibrotic polyp with disorganized mucosa and splaying of muscularis mucosae; also inflammatory, ... Raised mucosa/submucosa with inflammation If dysplasia develops Inflammatory bowel disease, ulcers, infections, mucosal ... They are overgrowths of the mucosa that frequently accompany allergic rhinitis. They are freely movable and nontender. ...
Pterygopalatine ganglion
... and its axons project to the lacrimal glands and nasal mucosa. The flow of blood to the nasal mucosa, in particular the venous ... The pterygopalatine ganglion supplies the lacrimal gland, paranasal sinuses, glands of the mucosa of the nasal cavity and ... The pterygopalatine ganglion (Meckel's ganglion, nasal ganglion or sphenopalatine ganglion) is a parasympathetic ganglion found ... The nasal glands are innervated with secretomotor from the greater petrosal nerve. Likewise, the palatine glands are innervated ...
OXGR1
Shirasaki H, Kanaizumi E, Himi T (2016). "Expression and localization of GPR99 in human nasal mucosa". Auris, Nasus, Larynx. ... and nasal mucosa, particularly the vascular smooth muscle in the latter tissue. In mice, Gpr99 mRNA is expressed in kidneys, ... of LTE4 but not LTD4 by asthmatic subjects caused the accumulation of eosinophils and basophils in their bronchial mucosa; d) ...
Oxymetazoline
Bende M, Löth S (March 1986). "Vascular effects of topical oxymetazoline on human nasal mucosa". The Journal of Laryngology and ... It can reduce nasal airway resistance (NAR) up to 35.7% and reduce nasal mucosal blood flow up to 50%. Imidazolines are ... Some of these commercials showed men, women, and children using other brands of nasal sprays, and then standing upside down on ... Vasoconstriction of vessels results in relief of nasal congestion in two ways: first, it increases the diameter of the airway ...
Reindeer
Temperature gradient along the nasal mucosa is under physiological control. Incoming cold air is warmed by body heat before ... Like moose, caribou have specialised noses featuring nasal turbinate bones that dramatically increase the surface area within ... Reindeer have specialised counter-current vascular heat exchange in their nasal passages. ... "Aspects of nasal heat exchange in resting reindeer", Journal of Physiology, 340: 445-454, doi:10.1113/jphysiol.1983.sp014772, ...
Septoplasty
Adhesions and synachiae between septal mucosa and lateral nasal wall. Saddle nose due to over-resection of the dorsal wall of ... the nasal septum being the partition between the two nasal cavities. Ideally, the septum should run down the center of the nose ... Deviated nasal septum or "crooked" internal nose can occur at childbirth or as the result of an injury or other trauma. If the ... The nasal tissues should mostly stabilize within 3-6 months post-surgery, although shifting is still possible for up to and ...
Coca
"A preliminary study of cocaine absorption from the nasal mucosa". Laryngoscope. 109 (1): 98-102. doi:10.1097/00005537-199901000 ... Absorption of coca from the leaf is less rapid than nasal application of purified forms of the alkaloid (almost all of the coca ... alkaloid is absorbed within 20 minutes of nasal application, while it takes 2-12 hours after ingestion of the raw leaf for ...
CHRNA6
2003). "Nicotinic cholinergic receptor expression in the human nasal mucosa". Ann. Otol. Rhinol. Laryngol. 112 (1): 77-84. doi: ...
SLPI
It is found in large quantities in bronchial, cervical, and nasal mucosa, saliva, and seminal fluids. SLPI inhibits human ... SLPI is also one of the dominantly present proteins in nasal epithelial lining fluid and other nasal secretions. Tissue SLPI ... "Localisation of secretory leucocyte proteinase inhibitor mRNA in nasal mucosa". Acta Oto-Laryngologica. 114 (2): 199-202. doi: ... Increased levels of SLPI in nasal secretions and bronchoalveolar fluids may be denotive of inflammatory lung conditions or ...
Immunoglobulin E
"Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis". J. Immunol. 174 (8): 5024-32. doi:10.4049/ ... with normal IgE levels in their blood-recent research has shown that IgE production can occur locally in the nasal mucosa.[20] ...
List of parasites of humans
nasal mucosa came into contact with infected material through bathing in common ponds ... Extranodal NK/T-cell lymphoma, nasal type. MCPyV Merkel-cell carcinoma. RNA virus. HCV Hepatocellular carcinoma. Splenic ... intestinal mucosa, may become invasive in some patients stool (diarrhea=ciliated trophozoite; solid stool=large cyst with ... nasal insufflation of contaminated warm fresh water, poorly chlorinated swimming pools, hot springs, soil ...
TST (gene)
1991). "The cyanide-metabolizing enzyme rhodanese in human nasal respiratory mucosa". Toxicol. Appl. Pharmacol. 108 (1): 114-20 ... Malliopoulou VA, Rakitzis ET, Malliopoulou TB (1989). "Inactivation of rhodanese from human gastric mucosa and stomach ...
Carbonic anhydrase 14
2004). "Gene expression for carbonic anhydrase isoenzymes in human nasal mucosa". Chem. Senses. 28 (7): 621-9. doi:10.1093/ ...
Parachlamydia acanthamoebae
"Acanthamoeba from human nasal mucosa infected with an obligate intracellular parasite". European Journal of Protistology. 30 (1 ... Using a nasal swab from volunteers, they were able to isolate coccoid-shaped bacteria that were present among other naturally- ...
Cysteinyl leukotriene receptor 2
2003). "Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa". Clin. Exp. Allergy. 32 (7 ...
Xerostomia
Dryness of other mucosae, e.g., nasal, laryngeal, and/or genital.[1] ... Saliva substitutes - These are viscous products which are applied to the oral mucosa, which can be found in the form of sprays ... Lozenges are soft and gentle on the mouth and there is a belief that prolonged contact with the oral mucosa mechanically ...
Rhinolith
They may cause pressure necrosis of the nasal septum or lateral wall of nose. Rhinoliths can cause nasal obstruction, epistaxis ... Nosebleed and pain may occur due to the ulceration of surrounding mucosa.[citation needed] They are removed under general ... A rhinolith is a stone present in the nasal cavity. The word is derived from the roots rhino- and -lith, literally meaning " ... They can be diagnosed from the history with unilateral foul-smelling blood-stained nasal discharge or by anterior rhinoscopy. ...
Reverse zoonosis
Kittens acquired massive lesions in the lungs, nasal and tracheal mucosa epitheliums. Surveillance for SARS-CoV-2 in cats ...
Xylometazoline
It binds to α1 and α2 adrenergic receptors in the nasal mucosa. Due to its sympathomimetic effects, it should not be used by ... "Xylometazoline nasal medical facts from Drugs.com". www.drugs.com. Archived from the original on 29 December 2016. Retrieved 28 ... The smaller arteries are also constricted and this causes the colour of the nasal epithelium to be visibly paler after dosage. ... Moreover, long-term overdosing can cause degenerative changes in nasal mucous membranes that pose another health problem.[ ...
Limfocyty T regulatorowe, wolna encyklopedia
Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa. „J Allergy Clin Immunol". 121 (6), s ...
Ndryshimi mes inspektimeve të "Përdoruesi:Tiimiii/I ftohti i zakonshem"
... colds are defined as upper respiratory tract infections that affect the predominantly nasal part of the respiratory mucosa,via ... 2 using a nasal gel) showed that the zinc treatment had a beneficial effect and 7 (5 using zinc lozenges, 1 using a nasal spray ... nasal sprays, and nasal gels on the common cold [69]. Of the 14 randomized, placebo-controlled studies included, 7 (5 using ... Nasal decongestants for the common cold,url=,journal=Cochrane Database Syst Rev,language=en,volume=,issue=1,page=CD001953,pages ...
Dental trauma
Areas normally affected are lips, buccal mucosa, gingivae, frenum and tongue. The most common injuries are lips and gingivae. ... Nasal fracture. *Le Fort fracture of skull. *Zygomaticomaxillary complex fracture. *Zygoma fracture ... The facial nerve and parotid duct should be examined for any potential damage when the buccal mucosa is involved. ... Facial nerve should be examined for any potential damage when buccal mucosa is involved. ...
Olfactory system
"Uptake of manganese and cadmium from the nasal mucosa into the central nervous system via olfactory pathways in rats". ... retro-nasal olfaction).[2] Inside the nasal cavity, mucus lining the walls of the cavity dissolves odor molecules. Mucus also ... CHEN, M; LANDER, T; MURPHY, C (May 2006). "Nasal health in Down syndrome: A cross-sectional study". Otolaryngology-Head and ... The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium ( ...
Granulomatosis with polyangiitis
Treatment measures for localised GPA of the nose and sinuses includes nasal irrigation, nasal corticosteroids, and antibiotics ... non-specific ulcerations throughout oral mucosa[14] ... Nasal or oral inflammation: *painful or painless oral ulcers or ... Typical signs and symptoms include nosebleeds, stuffy nose and crustiness of nasal secretions, and inflammation of the uveal ... Mendenhall WM, Olivier KR, Lynch JW, Mendenhall NP (April 2006). "Lethal midline granuloma-nasal natural killer/T-cell lymphoma ...
Human digestive system
Within its mucosa are millions of embedded gastric glands. Their secretions are vital to the functioning of the organ. ... The roof of the mouth is termed the palate and it separates the oral cavity from the nasal cavity. The palate is hard at the ... Most of the oral cavity is lined with oral mucosa, a mucous membrane that produces a lubricating mucus, of which only a small ... It is the part of the throat immediately behind the nasal cavity at the back of the mouth and above the esophagus and larynx. ...
Duck plague
Due to the formation of diptheroid plaques on the eyelids and the mucosae of the respiratory system and gastrointestinal system ... Symptoms in individual birds include loss of appetite, decreased egg production (nearing 20-40% decreases), nasal discharge, ...
Cool flame
... it is characterized by the release of a vapor whose sharp and penetrating odor strongly irritates the nasal mucosa and ...
ಅಲರ್ಜಿ - ವಿಕಿಪೀಡಿಯ
swelling of the nasal mucosa ಮೂಗಿನ ಹೊರಳೆಯಲ್ಲಿನ ಲೊಳೆ ಸುರಿಸುವ ಭಾಗದ ಊತ,ಅಲರ್ಜಿಕ್ ಗುರುಳೆಗಳು ...
Smallpox
Once inhaled, variola major virus invaded the oropharyngeal (mouth and throat) or the respiratory mucosa, migrated to regional ... Transmission occurred through inhalation of airborne Variola virus, usually droplets expressed from the oral, nasal, or ... pharyngeal mucosa of an infected person. It was transmitted from one person to another primarily through prolonged face-to-face ...
Decongestant
... receptor since they mediate vasoconstriction and constricting nasal vasculature causes decongestion of nasal mucosa. This ... For their nasal delivery system, see inhaler.. A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is ... Nasal spray. References[edit]. *^ Robert D. Ficalora (28 May 2013). Mayo Clinic Internal Medicine Board Review. Oxford ... Topical nasal or ophthalmic decongestants quickly develop tachyphylaxis (a rapid decrease in the response to a drug after ...
Cisteinil leukotrienski receptor 1 - Википедија, слободна енциклопедија
2003). „Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa.". Clin. Exp. Allergy. 32 (7 ...
කොවිඩ්-19 - විකිපීඩියා
Nasal polyp. Rhinorrhea. nasal septum Nasal septum deviation. Nasal septum perforation. Nasal septal hematoma. tonsil. ... "High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa". International Journal of Oral Science ... Extranodal NK/T-cell lymphoma, nasal type. MCPyV Merkel-cell carcinoma. RNA virus. HCV Hepatocellular carcinoma. Splenic ...
Bird anatomy
The skull consists of five major bones: the frontal (top of head), parietal (back of head), premaxillary and nasal (top beak), ... The digestion products are then absorbed through the intestinal mucosa into the blood. The intestine ends via the large ... and filtered in the nasal passages and upper parts of the trachea.[30] From there, the air enters the lower trachea and ...
ਛਿੱਕ - ਵਿਕੀਪੀਡੀਆ, ਇਕ ਅਜ਼ਾਦ ਵਿਸ਼ਵਗਿਆਨਕੋਸ਼
Irritants of the nasal mucosa. Light. Cold air. Sanitation. Infection. ਢੰਗ. Expulsion of air through nose/mouth. ... The function of sneezing is to expel mucus containing irritants from the nasal cavity. ...
পাকস্থলী - উইকিপিডিয়া
নাসাগহ্বর (Nasal cavity). *নাসাগলবিল (Nasopharynx). *স্বরযন্ত্র (Larynx). *অধোশ্বাসপথ (Lower respiratory tract). *শ্বাসনালী ( ... Gastric mucosa *Muscularis mucosa. *Gastric rugae. *Gastric pits. *Gastric gland. *Cardiac glands ...
Levobunolol
If the substance reaches the nasal mucosa via the tear duct, it can be absorbed into the bloodstream and cause systemic side ...
Face transplant
... oral mucosa, some of the salivary glands and the skin of his face (from below the eyelids to the neck and from ear to ear). The ... the nasal structure, the nose, the lips, the muscles of facial movement used for expression, the nerves that provide sensation ... teeth and nasal cavity, and was since then unable to eat. She had undergone around 35 reconstructive plastic surgery operations ...
Ethmoid sinus
Lateral wall of nasal cavity; the three nasal conchæ have been removed. ... The posterior group (sometimes the posterior ethmoidal sinus) drains into the superior meatus above the middle nasal concha; ... They lie between the upper parts of the nasal cavities and the orbits, and are separated from these cavities by thin bony ...
Warfarin
FWS is characterized mainly by skeletal abnormalities, which include nasal hypoplasia, a depressed or narrowed nasal bridge, ... This increased risk is due to the anti-platelet effect of NSAIDs as well as the possible damage to the gastrointestinal mucosa. ...
History of general anesthesia
Murphy, P (July 1967). "A fibre-optic endoscope used for nasal intubation". Anaesthesia. 22 (3): 489-91. doi:10.1111/j.1365- ... topical application of local anesthetics to the mucosa, rectal anesthesia, or intravenous anesthesia. While otherwise effective ...
Difin, Pozê mirov - Wîkîpediya
Nasal conchae/meatus: Superior nasal concha · Middle nasal concha · Inferior nasal concha · Superior nasal meatus · Middle ... nasal meatus · Inferior nasal meatus. Sphenoethmoidal recess · Ethmoid bulla · Agger nasi · Ethmoidal infundibulum · Semilunar ...
COVID-19, a enciclopedia libre
Oxíxeno nasal de fluxo alto Para SpO2 ,93%. Pode impedir a necesidade de intubación e ventilación ... "High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa". International Journal of Oral Science ... fluxo nasal, ou dor de garganta. Tamén se observan en variadas porcentaxes síntomas como náuseas, vómitos e diarrea.[33][37][38 ... tamén se pode utilizar unha mostra de frotis nasal ou esputo.[20][70] Xeralmente os resultados están listos en poucas horas ou ...
Corticosteroid
For nasal mucosa, sinuses, bronchii, and lungs.[34] This group includes: *Flunisolide[35] ... from anti-allergy nasal sprays (Nasonex, Flonase) to topical skin creams, to eye drops (Tobradex), to prednisone have been ...
Nasal mucosa: MedlinePlus Medical Encyclopedia Image
CBD Oil/Tincture through nasal mucosa? | Yahoo Answers
Im aware that some substances can be absorbed through the mucus membranes inside of the nostrils and nasal cavities. Does ... I am aware that there are companies that make CBD nasal sprays (strangely enough) as well as topical items, however research ... CBD Oil/Tincture through nasal mucosa?. Okay, I know that started off weird but just hang in here with me. My mother has severe ... Im aware that some substances can be absorbed through the mucus membranes inside of the nostrils and nasal cavities. Does ...
What is the Nasal Mucosa? (with pictures)
The nasal mucosa is the tissue that lines the nasal cavity, which is made up of four layers. The main purpose of the nasal ... The nasal mucosa, also known as the mucous membrane and respiratory mucosa, is the tissue that lines the nasal cavity. The ... The nasal mucosa is moist tissue that secretes mucous. This mucous lines the nasal cavity in order to catch bacteria and other ... Most people are familiar with nasal mucosa and how it helps keep out infections but few people know that we also require nasal ...
Nasal mucosa - Wikipedia
The nasal mucosa lines the nasal cavity. It is part of the respiratory mucosa, the mucous membrane lining the respiratory tract ... The nasal mucosa is intimately adherent to the periosteum or perichondrium of the nasal conchae. It is continuous with the skin ... The epithelium of the nasal mucosa is of two types - respiratory epithelium, and olfactory epithelium differing according to ... It is also thick over the nasal septum where increased numbers of goblet cells produce a greater amount of nasal mucus. It is ...
Salicylic Acid Promotes Nasal Mucosa Colonization
Nasal Mucosa Graft to Deliver Drugs Through Blood-Brain Barrier
Effects of an alpha2-adrenoceptor agonist in nasal mucosa. | Sigma-Aldrich
Correlation of Local FOXP3-Expressing T Cells and Th1-Th2 Balance in Perennial Allergic Nasal Mucosa
Nuclear alterations in nasal mucosa epithelial cells of students exposed to formaldehyde
The nasal mucosa cells were collected by scraping the nasal cavity with a wooden spatula that was previously moistened with ... Micronuclei in nasal mucosa, oral mucosa and lymphocytes in students exposed to formaldehyde vapor in anatomy class. Biomed ... Alteraciones en los núcleos de las células epiteliales de la mucosa nasal de los estudiantes expuestos a formaldehído ... Nasal mucosa changes in students exposed to formaldehyde vapour. Indian J of Otolaryngol Head Neck Surg. 2002; (54): 18-19. [ ...
Illustration of nose & nasal mucosa - Stock Image P414/0007 - Science Photo Library
The nasal cavity forms part of the system of airways that conducts air to and from the lungs. The walls of the conducting ... Illustration of the human nasal passage with an enlarged section showing its histology. ... Keywords: anatomy, human body, mucosa, nasal, nasal mucosal epithelium, nose, olfaction, olfactory, olfactory sense, sense, ... Caption: Illustration of the human nasal passage with an enlarged section showing its histology. The nasal cavity forms part of ...
Influence of topical antifungal drugs on ciliary beat frequency of human nasal mucosa: an in vitro study. - PubMed - NCBI
Human nasal mucosa was acquired during routine endoscopic sinus surgery. Cells were cultivated on object slides and exposed to ... Influence of topical antifungal drugs on ciliary beat frequency of human nasal mucosa: an in vitro study.. Hofmann T1, Reinisch ... The aim of this research was to study the effects of antifungal drugs on ciliary beat frequency (CBF) of human nasal mucosa ... Case series of in vitro experiments and in vitro study of cultured ciliated cells of human nasal mucosa. ...
Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis - Liu - 2010 - Allergy -...
Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis. Authors. *. F. Liu,. * ... Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis. Allergy 2010; 65: 1149- ... Methods: Inferior nasal turbinate tissue was obtained from 12 PER, 12 IAR and 12 nonallergic nonrhinitic (control) patients, ... study suggest that PER is characterized by a significantly greater eosinophilic and predominantly Th2 cell-mediated nasal ...
Itchy Nasal Mucosa and Multiple Joints: 1 Cause
There is 1 somewhat common condition that can cause Itchy Nasal Mucosa and Multiple Joints. ... The freeMD virtual doctor has found 1 condition that can cause Itchy Nasal Mucosa and Multiple Joints. ... Itchy Nasal Mucosa and Multiple Joints 1 Cause. The freeMD virtual doctor has found 1 condition that can cause Itchy Nasal ... There is 1 somewhat common condition that can cause Itchy Nasal Mucosa and Multiple Joints.. *Drug Side Effect ...
Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not...
... in nasal mucosa of 15 atopic children and ten atopic adults.. METHODS: Explanted mucosa was cultured with allergen with or ... Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not ... Lipopolysaccharide inhibits allergic inflammation in nasal mucosa of atopic children by skewing local immune responses from Th2 ... and four times in expression of interleukin 10 compared with mucosa stimulated with allergen alone. This difference in response ...
Occupational exposure to formaldehyde and histopathological changes in the nasal mucosa. | Occupational & Environmental Medicine
C60 for nasal mucosa - C60Oil - LONGECITY
Is it possible and does it make sense to apply C60 to nasal mucosa? I have issues with nose dryness and minor crust (few year ... C60 for nasal mucosa - posted in C60Oil: Hello, ... C60 for nasal mucosa. Started by Redbulloid , Mar 07 2019 07:53 ... Is it possible and does it make sense to apply C60 to nasal mucosa? I have issues with nose dryness and minor crust (few year ... Oil should stay on mucosa for some time and then moved away by epithelium. ...
ICD-10-PCS Code 09TK0ZZ - Resection of Nasal Mucosa and Soft Tissue, Open Approach - Codify by AAPC
ICD-10-PCS code 09TK0ZZ for Resection of Nasal Mucosa and Soft Tissue, Open Approach is a medical classification as listed by ... Resection of Nasal Mucosa and Soft Tissue, Open Approach 09TK0ZZ. ICD-10-PCS code 09TK0ZZ for Resection of Nasal Mucosa and ... Nasal cavity , Nostril","3")>Nasal Mucosa and Soft Tissue. Definition: Cutting through the skin or mucous membrane and any ... Includes: Columella , External naris , Greater alar cartilage , Internal naris , Lateral nasal cartilage , Lesser alar ...
In vitro nasal mucosa gland-like structure formation on a chip - Lab on a Chip (RSC Publishing)
In vitro nasal mucosa gland-like structure formation on a chip K. Na, M. Lee, H. Shin and S. Chung, Lab Chip, 2017, 17, 1578 ... The aim of this study was to produce an in vitro human nasal mucosa model for reliable drug screening and clinical applications ... Morphological and functional similarities between in vivo nasal mucosa and our model indicated its utilization as a reliable ... Furthermore, our in vitro nasal mucosa presented different appearance and characteristics under hypoxic conditions. ...
Treatment of Hereditary Hemorrhagic Telangiectasia of the Nasal Mucosa by Intranasal Bevacizumab : Search for Effective Dose |...
A Safety Study to Compare the Effect of Two PrEP-001 Nasal Powder Formulations on Nasal Mucosa and Serum Cytokine Production -...
A Safety Study to Compare the Effect of Two PrEP-001 Nasal Powder Formulations on Nasal Mucosa and Serum Cytokine Production. ... A Safety Study to Compare the Effect of Two PrEP-001 Nasal Powder Formulations on Nasal Mucosa and Serum Cytokine Production ... Randomised Study to Compare the Effect of Two PrEP-001 Nasal Powder Formulations on Nasal Mucosa and Serum Cytokine Production ... Any finding in the medical history review, physical examination (including nasal exam with nasal speculae), screening ...
Expression of members of the phospholipase A2 family of enzymes in human nasal mucosa
1. Phospholipase A2 expression in the human nasal mucosa. Open this publication in new window or tab ,,Phospholipase A2 ... 2. Phospholipase A2 expression in the human nasal mucosa. Open this publication in new window or tab ,,Phospholipase A2 ... Expression of members of the phospholipase A2 family of enzymes in human nasal mucosa. Lindbom, John Linköping University, ... The relative abundances of the different PLA2 transcripts in normal human nasal mucosa were found to be X ≈ IVA , IIA ≈ IIE ≈ ...
ICD-10-PCS Code 090K4KZ -Alteration of Nasal Mucosa and Soft Tissue with Nonautologous Tissue Substitute, Percutaneous...
ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma | The...
ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma. Karim ... ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma ... ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma ... ICOS-Expressing CD4 T Cells Induced via TLR4 in the Nasal Mucosa Are Capable of Inhibiting Experimental Allergic Asthma ...
CiNii 論文 -
Inhibitory Effect of Lactobacillus gasseri TMC0356 and Lactobacillus GG on...
Inhibitory Effect of Lactobacillus gasseri TMC0356 and Lactobacillus GG on Enhanced Vascular Permeability of Nasal Mucosa in ... TMC0356 might alleviate nasal allergic symptoms by suppressing the increase in nasal vascular permeability caused by local ... The nasal vascular permeability of ovablumin (OVA)-sensitized Brown Norway rats was evaluated by analyzing a brilliant blue ... Oral administration of ,I,Lactobacillus,/I, GG and ,I,L. gasseri,/I, TMC0356 significantly inhibited the increase in nasal ...
Targeted Disruption of the Olfactory Mucosa-Specific Cyp2g1 Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland,...
Targeted Disruption of the Olfactory Mucosa-Specific Cyp2g1 Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland, ... Targeted Disruption of the Olfactory Mucosa-Specific Cyp2g1 Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland, ... Targeted Disruption of the Olfactory Mucosa-Specific Cyp2g1 Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland, ... Targeted Disruption of the Olfactory Mucosa-Specific Cyp2g1 Gene: Impact on Acetaminophen Toxicity in the Lateral Nasal Gland, ...
In Situ Naphthalene Bioactivation and Nasal Airflow Cause Region-Specific Injury Patterns in the Nasal Mucosa of Rats Exposed...
In Situ Naphthalene Bioactivation and Nasal Airflow Cause Region-Specific Injury Patterns in the Nasal Mucosa of Rats Exposed ... In Situ Naphthalene Bioactivation and Nasal Airflow Cause Region-Specific Injury Patterns in the Nasal Mucosa of Rats Exposed ... In Situ Naphthalene Bioactivation and Nasal Airflow Cause Region-Specific Injury Patterns in the Nasal Mucosa of Rats Exposed ... In Situ Naphthalene Bioactivation and Nasal Airflow Cause Region-Specific Injury Patterns in the Nasal Mucosa of Rats Exposed ...
Conditioned medium from umbilical cord mesenchymal stem cells improves nasal mucosa damage by radiation | Springer for Research...
... on nasal mucosa radiation damage both in vivo and in vitro. ... on nasal mucosa radiation damage both in vivo and in vitro. ... Cytokines Conditioned medium Mesenchymal stem cells Nasal mucosa Radiation damage This is a preview of subscription content, ... Duan HG, Ji F, Zheng CQ, Wang CH, Li J (2014) Human umbilical cord mesenchymal stem cells alleviate nasal mucosa radiation ... Conditioned medium from umbilical cord mesenchymal stem cells improves nasal mucosa damage by radiation. ...
Nasal Mucosa Stock Image Search Results
Nasal Mucosa,Medical Illustration database of the best portfolios and stock images now features General and Commercial ... Sagittal section of dog head showing nasal cavity structures including the nasal mucosa, conchae, sinuses, pharynx, larynx, ... ... Fractured (Broken) Nose - Reconstruction Surgery of Nasal Bone Fractures with Osteotomy and Realignment of the Nasal Septum. # ... Nasal Polyp Surgery series - 11 full color airbrush illustrations of The Anterior Ethmoidal Approach to the Frontal Nasal Sin ...
Naegleria fowleri immunization modifies lymphocytes and APC of nasal mucosa. | Physician's Weekly for Medical News, Journals &...
Naegleria fowleri immunization modifies lymphocytes and APC of nasal mucosa. by Physicians Weekly , Dec 17, 2017 , 0 comments ... antibody that we previously found interacting with trophozoites in the nasal lumen avoiding the N. fowleri attachment to nasal ... nasal passages (NP) and spleen (SP). In all immunized groups, the percentage of CD4 was higher than CD8 cells. CD45 was ...
T cell dominated inflammatory reactions in the bronchioles of asymptomatic asthmatics are also present in the nasal mucosa. |...
Endobronchial and nasal mucosa biopsies were obtained from 5 patients with clinically-stable, diagnosed asthma (ATS criteria). ... Increases in HLA-DR expression were also seen in the nasal mucosa biopsies from asthmatics although the increases over normal ... T cell dominated inflammatory reactions in the bronchioles of asymptomatic asthmatics are also present in the nasal mucosa. ... T cell dominated inflammatory reactions in the bronchioles of asymptomatic asthmatics are also present in the nasal mucosa. ...
CavityPolypsSeptumNoseRhinitisOlfactory mucosaMucousTissuesInflammationCavitiesMucusEpithelium of the nasal mucosaColonization of the nasal mucosaObstructionAbstractPolyposisSinusEosinophilsMethodsVitroBiopsiesNormal nasalAnatomyAirwayInflammatory cellsHumansEndothelial cellsSymptomsConchaeTissueCongestionDevelopment of nasalHumanAllergenChronicEpithelial cells obtainedCellsInferior nasalBacterialVascularFormaldehydeMembraneLateralConclusionsMeatusSignificantlyStaphylococcusUlcerationPatients with nasal
Cavity18
- The mucosa, or mucous membrane, is a type of tissue that lines the nasal cavity. (medlineplus.gov)
- The nasal mucosa lines the nasal cavity. (wikipedia.org)
- The nasal mucosa , also known as the mucous membrane and respiratory mucosa, is the tissue that lines the nasal cavity . (wisegeek.com)
- This mucous lines the nasal cavity in order to catch bacteria and other materials that enter the nose. (wisegeek.com)
- The nasal cavity is particularly susceptible to infection and other problems because of its exposure to the environment. (wisegeek.com)
- The mucous produced within the nasal cavity is different and of a thinner consistency than the mucous in the ear. (wisegeek.com)
- The bottom layer of the nasal cavity tissue, under the basement membrane, is the lamina propria, which is filled with blood vessels and seromucosal glands. (wisegeek.com)
- Cilia are small, hair-like fibers that line the nasal cavity walls and protect the tissue from infection. (wisegeek.com)
- Another way the nasal cavity lining prepares air to enter the respiratory system is by warming it with the heat radiating from the blood vessels within the lamina propria. (wisegeek.com)
- Rhinitis is a general term that describes any condition that results in infected and irritated nasal cavity lining. (wisegeek.com)
- The nasal cavity forms part of the system of airways that conducts air to and from the lungs. (sciencephoto.com)
- The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. (uchicago.edu)
- with the exception of the olfactory mucusa, it includes the entire nasal cavity. (thefreedictionary.com)
- What are two functions of the mucosa found in the nasal cavity? (reference.com)
- The mucosa, or mucus membrane, that can be found in the nasal cavity is highly vascular, helping to warm and moisten incoming air and is important for smel. (reference.com)
- It lies below the inferior concha and above the nasal cavity. (wikipedia.org)
- A cationic lipid emulsion was formulated with soybean oil and 1,2-dioleoyl-sn-glycero-3-trimethylammonium-propane (DOTAP) as major components and was used to transfer genes to the epithelial cells of the mouse nasal cavity via intranasal instillation. (elsevier.com)
- The transfection activities of the lipid carriers in nasal cavity mucosae are in agreement with the stability of the lipid carriers and their complexes with DNA. (elsevier.com)
Polyps15
- The factors involved in the development of chronic inflammation and edema in nasal polyps remain to be clarified. (semanticscholar.org)
- The expression of vascular endothelial growth factor (VEGF) has been described in plasma cells, suggesting that plasma cells may play a major role in the development of edema in nasal polyps through the production of VEGF. (semanticscholar.org)
- Inflammatory cells as well as epithelial cells in nasal polyps express vascular endothelial growth factor. (semanticscholar.org)
- Will I ever get rid of my nasal polyps? (enthelp.com)
- Expression of Glucocorticoid Receptor in Nasal Polyps and Nasal Mucosa. (kjorl.org)
- Multifactorial effects of glucocorticoid are initiated by their binding to a specific cytoplasmic glucocorticoid receptor (GR). We performed this study to investigate the localization and distribution ot' human 4R and GR j3 isoform in nasal mucosa and to examine the influence of allergy and eosinophilic infiltration on GR and GR betaisoform expression in nasal polyps. (kjorl.org)
- Nasal polyps (NP), middle turbinate mucosa (MT) and inferior turbinate (IT) mucosa were taken from 40 patients with chronic sinusitis and nasal polyps. (kjorl.org)
- In the present study we evaluated the presence of mRNAs for human guanylin and uroguanylin in human inferior turbinate mucosa and nasal polyps. (elsevier.com)
- Material and Methods - The expression and localization of mRNAs for both peptides were investigated in inferior turbinate tissues and nasal polyps using reverse transcriptase polymerase chain reaction and in situ hybridization. (elsevier.com)
- Results - mRNAs for both peptides were detected in human turbinate mucosa and nasal polyps. (elsevier.com)
- In situ hybridization revealed that they were localized in the epithelial layer and submucosal glands of inferior turbinate mucosa and in the epithelial layer of nasal polyps. (elsevier.com)
- However, their expression was noted at low levels in the superficial epithelium of nasal polyps, compared with that of inferior turbinate mucosa. (elsevier.com)
- Conclusions - These results indicate that guanylin and uroguanylin in the nasal mucosa may participate in normal physiological processes, but also suggest that altered expression of these genes in nasal polyps may cause impaired electrolyte and water transport across the epithelial cells. (elsevier.com)
- Nasal polyps drip im sure. (medhelp.org)
- the same pattern of expression was found in perennial rhinitis (B) and nasal polyps (C) (hematoxylin, original magnification ×400). (jamanetwork.com)
Septum10
- It is also thick over the nasal septum where increased numbers of goblet cells produce a greater amount of nasal mucus. (wikipedia.org)
- The nonolfactory mucosa on the nasal septum, a high airflow region, metabolized naphthalene slowly, whereas the olfactory regions of the nasal septum and ethmoturbinates metabolized this substrate at high rates. (aspetjournals.org)
- Fractured (Broken) Nose - Reconstruction Surgery of Nasal Bone Fractures with Osteotomy and Realignment of the Nasal Septum. (indexedvisuals.com)
- The pronounced edema of the nasal mucosa and persistent congestion disturb in chronic polyposis, adenoiditis, curved nasal septum. (medhelpsis.com)
- Gross mucosal edema of the septum and turbinates was the main finding on nasal examination. (elsevier.com)
- The septal nasal cartilage , ( cartilage of the septum or quadrangular cartilage ) is composed of hyaline cartilage . (wikipedia.org)
- Moreover, the ELISA dosage of SIgA in nasal secretion, sampled by cotton swabs positioned between septum and middle turbinate for 20 minutes every 4 hours 5 times in a day, can be easily performed and shows significant differences between the healthy child and the healthy adult. (biomedcentral.com)
- Nasal secretions could be sampled by the insertion between the middle turbinate and the septum of swabs of cotton which are removed after 20 minutes and immediately squeezed out. (biomedcentral.com)
- Computed tomography of the paranasal sinuses showed only mucosal hypertrophy with a possible soft tissue mass in the inferior part of the nasal septum but no evidence of bony destruction. (bmj.com)
- An examination under anaesthetic showed no discrete mass but a biopsy of the nasal septum revealed inflammatory cells, macrophages, and mature B and T lymphocytes. (bmj.com)
Nose11
- This is why when we have a stuffy nose or other issues with our nasal membrane or mucus, we are not able to smell as well. (wisegeek.com)
- ICD-10-PCS code 09TK0ZZ for Resection of Nasal Mucosa and Soft Tissue, Open Approach is a medical classification as listed by CMS under Ear, Nose, Sinus range. (aapc.com)
- Moreover, this investigation demonstrates, for the first time, the presence of the newly discovered phospholipase A 2 forms IID, IIE, III, IVB, IVC, X and calcium-independent membrane bound phospholipase A 2 in the human nasal mucosa and raises the possibility that one or several of these may be involved in inflammatory reactions in the nose. (diva-portal.org)
- The nasal vascular permeability of ovablumin (OVA)-sensitized Brown Norway rats was evaluated by analyzing a brilliant blue concentration in perfusate from the nose after exposure of the nasal mucus to OVA. (nii.ac.jp)
- We investigated if intranasal immunization with amoebic lysates plus cholera toxin modified the populations of T and B lymphocytes, macrophages and dendritic cells by flow cytometry from nose-associated lymphoid tissue (NALT), cervical lymph nodes (CN), nasal passages (NP) and spleen (SP). (physiciansweekly.com)
- ICD-10-PCS code 09JKXZZ for Inspection of Nasal Mucosa and Soft Tissue, External Approach is a medical classification as listed by WHO under the range -Ear, Nose, Sinus. (aapc.com)
- The causes of edema are different, but most often the swelling of the mucosa in the nose appears with a cold and allergic rhinitis. (medhelpsis.com)
- Nasal congestion always appears during ARVI, when the nose is flowing snot, as well as at the end of the common cold, and is a herald of inflammation of the paranasal sinuses. (medhelpsis.com)
- If the above drugs do not help within 1-2 weeks, nasal glucocorticoids can be sprayed into the nose - Rinocort, Sintaris, Nasobek, etc. (medhelpsis.com)
- 10 documented a release of inflammatory mediators in nasal-wash fluids when compressed cold and dry air was delivered through the nose. (ersjournals.com)
- On examination his nose was red and swollen (see fig 1) with granular mucosa in the left nasal vestibule. (bmj.com)
Rhinitis16
- Liu F, Zhang J, Liu Y, Zhang N, Holtappels G, Lin P, Liu S, Bachert C. Inflammatory profiles in nasal mucosa of patients with persistent vs intermittent allergic rhinitis. (wiley.com)
- Morphological and functional similarities between in vivo nasal mucosa and our model indicated its utilization as a reliable research model for nasal diseases including allergic rhinitis, chronic sinusitis, and nasal polyposis. (rsc.org)
- This medical exhibit contrasts normal nasal passage anatomy with allergic rhinitis in a series of four illustrations. (indexedvisuals.com)
- In subjects with allergic rhinitis, allergen challenge led to parallel increases in eosinophil counts, levels of EPX and eotaxin concentrations in nasal lavage fluid. (nii.ac.jp)
- These results indicate that eotaxin has an important role in eosinophil-dependent inflammation in nasal mucosa and suggest that blocking eotaxin or CCR-3 might be useful for new therapeutic tools of allergic rhinitis. (nii.ac.jp)
- To gain a better understanding of the role of TARC in the pathogenesis of allergic rhinitis, we have investigated the cellular sources of this chemokine in nasal mucosa. (nii.ac.jp)
- Epithelial cells in nasal mucosa in subjects with allergic rhinitis expressed higher signal level than those in non-allergy patients. (nii.ac.jp)
- Microvascular remodeling of nasal mucosa in allergic rhinitis induced by an allergen in Sprague-Dawley rats. (semanticscholar.org)
- Glucocorticoids are currently the most potent medication available for the treatment of nasal polyposis and allergic rhinitis, but exact mechanisms and cellular targets in the nasal mucosa are uncertain. (kjorl.org)
- Gene and protein expression of protease-activated receptor 2 in structural and inflammatory cells in the nasal mucosa in seasonal allergic rhinitis. (ox.ac.uk)
- Here, the present study aimed to explore the expression of PAR 2 in the nasal mucosa of seasonal allergic rhinitis (SAR). (ox.ac.uk)
- Topical intranasal corticosteroids are currently used as the first line of treatment for rhinitis because they reduce the inflammation of the mucosa that underlies the signs and symptoms of the disease . (bvsalud.org)
- Inferior turbinates were obtained from patients suffering from either allergic or nonallergic rhinitis during corrective nasal surgery. (elsevier.com)
- Conclusions: Our findings suggest that decreasing sympathetic innervation may have a role in the pathophysiology of rhinitis and may be particularly significant in relation to glandular functions in allergic nasal mucosa. (elsevier.com)
- Wang, HW & Chu, YH 2005, ' Noradrenergic nerve fluorescence in the nasal mucosa of rhinitis patients ', Journal of Medical Sciences (Taiwan) , vol. 25, no. 4, pp. 185-189. (elsevier.com)
- Nasal obstruction is a crucial symptom in allergic rhinitis and it is primarily a vascular phenomenon caused by distension of the sinusoids with blood[ 10 ]. (biomedcentral.com)
Olfactory mucosa8
- CYP2G1 is a cytochrome P450 monooxygenase expressed uniquely in the olfactory mucosa (OM). (aspetjournals.org)
- Severe cellular injury occurred exclusively in the olfactory mucosa 24 h postinhalation exposure to 3.4 ppm NA for 4 h. (aspetjournals.org)
- Injury within the olfactory mucosa from inhaled NA was confined to the medial meatus, whereas systemic NA generated severe injury throughout the olfactory region. (aspetjournals.org)
- Among these, the olfactory mucosa (i.e., the olfactory epithelium and its underlying lamina propria) contains four primary cells: the duct cells lining Bowman's glands, basal cells, olfactory receptor cells, and the sustentacular cells or olfactory supporting cells. (aspetjournals.org)
- Therefore, the olfactory mucosa has the potential to metabolize protoxicants that require in situ bioactivation. (aspetjournals.org)
- For a number of species, including nonhuman primates, nasal tissue, especially olfactory mucosa, contains high concentrations of P450s. (aspetjournals.org)
- Changes in smell acuity induced by radiation exposure of the olfactory mucosa. (biomedsearch.com)
- The effects of ionizing radiation on smell acuity were assessed in 12 patients in whom the olfactory mucosa was exposed to radiation in the course of treatment for nasopharyngeal carcinoma or pituitary adenoma. (biomedsearch.com)
Mucous10
- It is part of the respiratory mucosa, the mucous membrane lining the respiratory tract. (wikipedia.org)
- It is continuous with the skin through the nostrils, and with the mucous membrane of the nasal part of the pharynx through the choanae. (wikipedia.org)
- The mucous membrane is thickest, and most vascular, over the nasal conchae. (wikipedia.org)
- The nasal mucosa is moist tissue that secretes mucous. (wisegeek.com)
- The mucous produced by the nasal mucosa is the body's answer to the vulnerability of exposed internal tissue. (wisegeek.com)
- The first layer within the nasal mucosa, under the mucous lining, is the pseudostratified columnar epithelium. (wisegeek.com)
- The mucous within the nasal mucosa not only serves to remove bacteria from the air entering the respiratory system, but it also humidifies, or adds moisture, to the air. (wisegeek.com)
- Even with the protective lining of mucous, the nasal mucosa remains quite susceptible to infection and inflammation . (wisegeek.com)
- Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells. (uchicago.edu)
- Introduction The main histological features of the nasal mucosa in choanal atresia are distorted cilia, marked increase of mucous submucosal glands associated with marked reduction of goblet cell density, and lymphocytic cellular infiltration. (arquivosdeorl.org.br)
Tissues7
- Methods Primary cultures of HNMFs were established from nasal mucosal tissues of patients undergoing DCR. (bmj.com)
- Nasal mucus is produced by the nasal mucosa , and mucal tissues lining the airways ( trachea , bronchus , bronchioles ) is produced by specialized airway epithelial cells ( goblet cells ) and submucosal glands . (wikia.org)
- Additionally, mucus aids in moisturizing the inhaled air and prevents tissues such as the nasal and airway epithelia from drying out. (wikia.org)
- These results suggest that aerosolization of soluble antigen formulations with CT may provide an alternative method of delivering nasal vaccines to sheep and other large animal species, and that further improvements in antigen penetration of nasal tissues may dramatically improve the strength of the immune response. (edu.au)
- Using immunohistochemistry, laser-assisted cell picking and subsequently real-time PCR, nasal mucosa biopsies of SAR patients were investigated for PAR 2 gene and protein expression in complex tissues of the nasal mucosa. (ox.ac.uk)
- The relative gene expression level of PAR 2 was significantly increased in complex tissues of the nasal mucosa of SAR (6.21+/-4.02 vs. controls: 1.38+/-0.86, P=0.004). (ox.ac.uk)
- The conjunctiva, part of the eye mucosa, has immunologic features in common with other mucosal tissues. (jimmunol.org)
Inflammation13
- We examined the effect of bacterial lipopolysaccharide on allergic inflammation and expression of cytokines and lipopolysaccharide receptor (toll-like receptor 4 TLR4) in nasal mucosa of 15 atopic children and ten atopic adults. (nih.gov)
- Lipopolysaccharide inhibits allergic inflammation in nasal mucosa of atopic children by skewing local immune responses from Th2 to Th1 and upregulating production of interleukin 10. (nih.gov)
- The precise roles of the different PLA 2 enzymes in airways inflammation are not known and the gene expression of the different PLA 2 s in the human nasal mucosa has not previously been examined. (diva-portal.org)
- TMC0356 might alleviate nasal allergic symptoms by suppressing the increase in nasal vascular permeability caused by local inflammation associated with allergic rhnititis. (nii.ac.jp)
- It is concluded that inflammation present in the nasal mucosa of asymptomatic asthmatics exhibits cellular characteristics also seen in endobronchial biopsies. (bmj.com)
- To evaluate the role of eotaxin in eosinophilic inflammation in nasal mucosa, we investigated the levels of eosinophil chemoattractants in nasal lavage fluids obtained after antigen challenge, and compared with eosinophil counts and eosinophil protein X (EPX) levels. (nii.ac.jp)
- With inflammation of the nasal mucosa or the effects of irritants, its vessels become inflamed and expand. (medhelpsis.com)
- With allergies the mucosa has a pale shade, with infectious inflammation it is red. (medhelpsis.com)
- Nasal brushing has sometimes been used to characterize some affections of the respiratory tract, but seldom employed in chronic diseases such as asthma, for the possible presence of cellular inflammation in the small specimens used for electron microscopy. (univr.it)
- In conclusion, nasal obstruction of OSA patients on CPAP treatment is inflammatory in origin and the addition of heated humidification decreases nasal resistance and mucosal inflammation. (ersjournals.com)
- 11 showed that CPAP employed in rats can trigger early nasal inflammation. (ersjournals.com)
- Our hypothesis was that nasal side effects of CPAP are inflammatory in origin and the addition of heated humidification attenuates nasal mucosal inflammation and decreases the elevated nasal resistance caused by the use of CPAP. (ersjournals.com)
- Propolis decreased inflammation and enhanced healing of wounds of the nasal mucosa in rats. (propolisscience.org)
Cavities4
- I'm aware that some substances can be absorbed through the mucus membranes inside of the nostrils and nasal cavities. (yahoo.com)
- It is very thin in the meatuses on the floor of the nasal cavities, and in the various sinuses. (wikipedia.org)
- The other 2 patients, after 18 and 23 months of achieving a patent choana, showed normal nasal cavities. (arquivosdeorl.org.br)
- [1] It is somewhat quadrilateral in form, thicker at its margins than at its center, and completes the separation between the nasal cavities in front. (wikipedia.org)
Mucus8
- Most people are familiar with nasal mucosa and how it helps keep out infections but few people know that we also require nasal mucus for our sense of smell. (wisegeek.com)
- Mucus is the carrier in which the tiny particles reach these receptors in the nasal membrane, which then communicate with the brain to tell us what we are smelling. (wisegeek.com)
- Small particles such as dust, particulate pollutants , and allergens as well as infectious agents such as bacteria are caught in the viscous nasal or airway mucus and prevented from entering the system. (wikia.org)
- [1] Nasal and airway mucus is produced constitutively, with most of it swallowed unconsciously, even when it is dried . (wikia.org)
- Tears are also a component of nasal mucus. (wikia.org)
- Generally nasal mucus is clear and thin, serving to filter air during inhalation. (wikia.org)
- ENT doctor examining nasal passages in special mirrors sees swollen mucus, discharge. (medhelpsis.com)
- Moreover, PAR 2 mRNA expression in epithelial cells (SAR: 4.78+/-4.64 vs. controls: 0.84+/-0.61, P=0.003) but not in mucus (SAR: 1.51+/-1.15 vs. controls: 1.35+/-1.02, P=0.78) and endothelial cells (SAR: 1.20+/-0.57 vs. controls: 1.73+/-1.30, P=0.5) was found to be significantly changed in the nasal mucosa in SAR. (ox.ac.uk)
Epithelium of the nasal mucosa1
- The epithelium of the nasal mucosa is of two types - respiratory epithelium, and olfactory epithelium differing according to its functions. (wikipedia.org)
Colonization of the nasal mucosa2
- Moreover, the treatment of mice with salicylic acid demonstrably resulted in prolonged colonization of the nasal mucosa by S. aureus. (infectioncontroltoday.com)
- Studies have highlighted the importance of T-cell immunity in controlling S. aureus colonization of the nasal mucosa. (tcd.ie)
Obstruction3
- The article distinguishes three groups of causes for symptoms of nasal congestion/obstruction, which are mucosal causes, structural causes and sensory causes. (oatd.org)
- 20 patients with OSA on nasal CPAP who exhibited symptomatic nasal obstruction were randomised to receive either 3 weeks of CPAP treatment with heated humidification or 3 weeks of CPAP treatment with sham-heated humidification, followed by 3 weeks of the opposite treatment, respectively. (ersjournals.com)
- Nasal obstruction and nasal discharge taken together were reported by 62.5% of patients. (elsevier.com)
Abstract1
- abstract = "Purpose: The inhalation of nasal snuff (powdered tobacco) is a common addiction in the Indian subcontinent. (elsevier.com)
Polyposis1
- Infiltration of the lamina propria by inflammatory cells in nasal polyposis. (jamanetwork.com)
Sinus5
- Human nasal mucosa was acquired during routine endoscopic sinus surgery. (nih.gov)
- The project describes histomorphologically and biochemically the healing process in human respiratory mucosa after sinus surgery and searches for modulating factors. (ugent.be)
- Nasal nitric oxide concentration in paranasal sinus inflammatory diseases. (semanticscholar.org)
- Five Cases of IgG4-related Disease with Nasal Mucosa and Sinus Involvement. (illumina.com)
- Nasal respiratory function grows up gradually in childhood together with nasal and sinus anatomical structure and immunological defences. (biomedcentral.com)
Eosinophils6
- Normal subjects had few, if any, eosinophils and EPX as well as the measured parameters in their nasal lavage fluids before and after antigen challenge. (nii.ac.jp)
- In addition, … More treatment of eosinophils with anti CCR3 mAb significantly blocked eosinophil TEM induced by homogenate of nasal mucosa. (nii.ac.jp)
- Epithelial cells may be an important site of action for intranasal steroids, and the increased number of eosinophils infiltrating the mucosa and allergy did not amplify the number of immunostaining of GK and GR beta isoform. (kjorl.org)
- Using double immunohistochemistry the present study demonstrated that the total numbers of mast cells (P=0.0003) and eosinophils (P=0.03) and the numbers of eosinophils expressing PAR 2 (P=0.006) were significantly elevated in the nasal mucosa of SAR compared with the controls. (ox.ac.uk)
- CONCLUSION: The abundant presence and distribution of gene and protein expression of PAR 2 in different cell types in the nasal mucosa under normal situation, the increased expression of PAR 2 in epithelial cells and the increased number of eosinophils with PAR 2 suggest that PAR 2 may contribute to the pathogenesis of allergic diseases such as SAR. (ox.ac.uk)
- Although either the amount of DP or the amount of CRTH2 was not correlated with serum levels of IgE, the amount of CRTH2 but not DP was highly and significantly correlated with the number of eosinophils infiltrating into nasal musosa. (elsevier.com)
Methods1
- Of the variety of methods used to treat nasal symptoms during CPAP treatment, the most common is heated humidification of the inspired air 13 . (ersjournals.com)
Vitro11
- Influence of topical antifungal drugs on ciliary beat frequency of human nasal mucosa: an in vitro study. (nih.gov)
- The aim of this research was to study the effects of antifungal drugs on ciliary beat frequency (CBF) of human nasal mucosa under in vitro conditions. (nih.gov)
- Case series of in vitro experiments and in vitro study of cultured ciliated cells of human nasal mucosa. (nih.gov)
- However, to date, few studies have reported the development of a complicated in vitro human nasal epithelial model. (rsc.org)
- The aim of this study was to produce an in vitro human nasal mucosa model for reliable drug screening and clinical applications. (rsc.org)
- Here, we integrated and optimized several culture conditions such as cell type, airway culture conditions, and hydrogel scaffolds into a microfluidic chip to construct an advanced in vitro human nasal mucosa model. (rsc.org)
- Furthermore, our in vitro nasal mucosa presented different appearance and characteristics under hypoxic conditions. (rsc.org)
- To explore therapeutic effects of conditioned medium from human umbilical cord mesenchymal stem cells (hUC-MSCs) on nasal mucosa radiation damage both in vivo and in vitro. (springer.com)
- Shao D, Massoud E, Clarke D, Cowley E, Renton K, Agu RU (2013) Optimization of human nasal epithelium primary culture conditions for optimal proton oligopeptide and organic cation transporters expression in vitro. (springer.com)
- Aim To determine the effect of mitomycin-C (MMC) on the contraction and migration of human nasal mucosal fibroblasts (HNMFs) in vitro in order to identify the least concentration of MMC required to prevent cicatrix development following dacryocystorhinostomy (DCR). (bmj.com)
- The drug increased resting tension in human nasal mucosa in vitro through direct actions and potentiated mucosal contractions by norepinephrine and epinephrine. (elsevier.com)
Biopsies6
- Endobronchial and nasal mucosa biopsies were obtained from 5 patients with clinically-stable, diagnosed asthma (ATS criteria). (bmj.com)
- The distribution of immunocompetent cells within the nasal biopsies of the asthmatic patients reflected a very similar inflammatory infiltrate to that seen in the bronchial biopsies. (bmj.com)
- Significantly raised numbers of T lymphocytes, CD45RO + lymphocytes, RFD1 + macrophage-like cells and RFD7 + macrophages were seen in both the nasal mucosa and the bronchial biopsies. (bmj.com)
- Increases in HLA-DR expression were also seen in the nasal mucosa biopsies from asthmatics although the increases over normal did not reach statistical significance. (bmj.com)
- Results Four biopsies (4 repaired choanal atresia sides) of the mucosa of the inferior turbinate revealed that 1 patient (who had a bilateral choanal atresia repaired), after achieving a patent choana for 8 months, had not completely recovered a normal nasal mucosa. (arquivosdeorl.org.br)
- Nasal turbinate biopsies were taken from house dust mite allergic patients, before and after nasal allergen provocation. (biomedcentral.com)
Normal nasal1
- The epithelium of the normal nasal mucosa shows intense annexin A1 staining in the ciliated cells, especially within the cilia. (jamanetwork.com)
Anatomy4
- We aimed to investigate whether exposure to this compound was correlated with the appearance of cytotoxic and genotoxic features in the nasal epithelial cells of students enrolled in a human anatomy course. (isciii.es)
- This prospective study collected periodically nasal cells from mucosa of 17 volunteers from two different undergraduate programs with different workloads of practical lessons in an anatomy laboratory, 30 and 90 hours per semester. (isciii.es)
- Anatomy figure: 33:02-01 at Human Anatomy Online, SUNY Downstate Medical Center - "Diagram of skeleton of medial (septal) nasal wall. (wikipedia.org)
- The nasal mucosa is characterized by a complex micro vascular anatomy. (biomedcentral.com)
Airway5
- It has been shown that interactions between CCR4 and MDC/CCL22 and TARC/CCL17, as well as between CCR8 and I-309/CCL1, are critical for the recruitment of Th2 cells in the airway mucosa of allergic diseases in response to allergen stimulation. (nii.ac.jp)
- Nasal continuous positive airway pressure (CPAP) can cause undesirable nasal symptoms, such as congestion to obstructive sleep apnoea (OSA) patients, whose symptoms can be attenuated by the addition of heated humidification. (ersjournals.com)
- Nasal continuous positive airway pressure (CPAP) is considered the standard of care for treating moderate-to-severe obstructive sleep apnoea (OSA) 1 . (ersjournals.com)
- Indeed, deliberate mouth leaks while normal subjects were using CPAP can cause high unidirectional nasal airflow with increased nasal airway resistance 8 as well as enhance nasal mucosal blood flux 9 . (ersjournals.com)
- In children there is no significant difference in IgG, IgA and IgE in nasal secretion between healthy subjects and those with recurrent upper airway infection, and only albumin values increase during infection [ 6 ]. (biomedcentral.com)
Inflammatory cells2
- Given that vascular endothelium form a gateway for inflammatory cells into the local mucosa, one possible explanation is that during endothelial transmigration the pro-inflammatory characteristics of cells entering the mucosa are dampened through the local exposure to endothelial IL-10. (biomedcentral.com)
- Lastly, the influx of inflammatory cells and mediators of the early and the late inflammatory phase from blood to the local tissue contributes to nasal blockage, rhinorrhoea, sneezing, and pruritus[ 11 ]. (biomedcentral.com)
Humans1
- In humans, significant expression/activity of P450s in the nasal mucosa have been reported. (aspetjournals.org)
Endothelial cells5
- We observed that the inducing factors for nasal gland-like structures were secreted from activated human dermal microvascular endothelial cells. (rsc.org)
- In our experiments of eosinophil endothelial transmigration (TEM) assay using the nasal microvascular endothelial cells, eotaxin showed most potent effect among various eosinophil chemoattractants. (nii.ac.jp)
- Interleukin-10 (IL-10) is a negative regulator of immune responses and was previously shown to be expressed by human nasal endothelial cells, while the adhesion molecule MECA-79 plays a role in trans-endothelial migration of immune competent cells. (biomedcentral.com)
- We previously found expression of Interleukin-10 (IL-10) on the endothelial cells in the nasal mucosa of allergic subjects. (biomedcentral.com)
- Furthermore, by opening the gaps in the intercellular junctions between the endothelial cells, extravasation of plasma takes places, which ultimately contributes to rhinorrhoea formation and swelling of the nasal mucosa. (biomedcentral.com)
Symptoms7
- Inferior nasal turbinate tissue was obtained from 12 PER, 12 IAR and 12 nonallergic nonrhinitic (control) patients, and symptoms (visual analogue scales, VAS) and impairment of life was monitored. (wiley.com)
- However, neither the nature of nasal symptoms nor the effect of heated humidification on nasal pathophysiology and pathology are convincingly known. (ersjournals.com)
- Among the side effects caused by CPAP, undesirable nasal symptoms such as congestion, dryness or rhinorrhea are particularly prevalent and can significantly compromise compliance 7 . (ersjournals.com)
- However, it remains unknown if the same mechanisms could be responsible for the nasal side effects of CPAP in OSA patients, who frequently have increased nasal symptoms even in the absence of CPAP use 12 . (ersjournals.com)
- Although several authors have studied the effect of different forms of humidification on the relative humidity of CPAP airflow, patient adherence and subjective outcomes 13 - 15 , no study has so far examined the functional pathways by which heated humidified CPAP attenuates nasal symptoms in OSA patients 16 . (ersjournals.com)
- A randomised, crossover, sham-controlled design was adopted, and nasal resistance, nasal wash inflammatory markers and pathology of nasal mucosa were examined in OSA patients using CPAP and exhibiting nasal symptoms. (ersjournals.com)
- At the time of the study, all patients complained of one or more nasal symptoms. (elsevier.com)
Conchae2
- The nasal mucosa is intimately adherent to the periosteum or perichondrium of the nasal conchae. (wikipedia.org)
- The nasal meatuses are located beneath each of the corresponding nasal conchae . (wikipedia.org)
Tissue3
- Mucosa is moist tissue that lines certain parts of the inside of your body. (medlineplus.gov)
- The ovine nasal mucosal environment has histological and ultrastructural features that resemble well-known inductive sites of mucosa-associated lymphoid tissue. (edu.au)
- In the present study, the nasal mucosa was assessed as a potential mucosal tissue site for delivering vaccines to sheep. (edu.au)
Congestion1
- Swelling of the nasal mucosa is manifested by difficulty in nasal breathing, congestion, nasal congestion and night snoring. (medhelpsis.com)
Development of nasal3
- Several mechanisms may be potentially involved in the development of nasal discomfort with CPAP but they have been described only in healthy volunteers 8 - 10 and in a rodent model 11 . (ersjournals.com)
- The development of nasal mucosa in the non-human primate, Macaca nemes" by Cheryl. (uwindsor.ca)
- The development of nasal mucosa in the non-human primate, Macaca nemestrina: Qualitative and quantitative analysis. (uwindsor.ca)
Human11
- Illustration of the human nasal passage with an enlarged section showing its histology. (sciencephoto.com)
- However, the precise contribution of different PLA 2 types to the formation of inflammatory lipid mediators in the upper airways is not known and the expression of different PLA 2 genes in the human nasal mucosa has not been examined. (diva-portal.org)
- These findings demonstrate that a large number of PLA 2 types are expressed in the normal human nasal mucosa. (diva-portal.org)
- Despite the fact that naphthalene (NA), a volatile, ubiquitous air pollutant, was recently identified as a probable human carcinogen, little is known about nasal cytotoxicity from inhaled NA. (aspetjournals.org)
- Duan HG, Ji F, Zheng CQ, Wang CH, Li J (2014) Human umbilical cord mesenchymal stem cells alleviate nasal mucosa radiation damage in a guinea pig model. (springer.com)
- Expression of C-C chemokine TARC in human nasal mucosa and its regulation by cytokines'Clin Exp Allergy. (nii.ac.jp)
- The effects of cocaine on the contractile response of isolated human nasal mucosal blood vessels to field stimulation and methoxamine were investigated. (elsevier.com)
- We evaluated the effects of urban air pollutants on human nasal mucosa over an 8-month period on 102 subjects living in Florence, Tuscany, Italy. (uniss.it)
- We sought to determine the expression of synthases and receptors for PGD2 in human nasal mucosa. (elsevier.com)
- Lindahl MSvartz JTagesson C Demonstration of different forms of the anti-inflammatory proteins lipocortin-1 and Clara cell protein-16 in human nasal and bronchoalveolar lavage fluids. (jamanetwork.com)
- Within our research into immune regulatory processes in the nasal mucosa, we have been focusing on structural cells in the human nasal mucosa. (biomedcentral.com)
Allergen2
- Explanted mucosa was cultured with allergen with or without lipopolysaccharide (0.1 mg/L) for 24 h. (nih.gov)
- In children but not in adults, lipopolysaccharide caused increases of three times in T-cell reactivity, five times in T-cell proliferation, and four times in expression of interleukin 10 compared with mucosa stimulated with allergen alone. (nih.gov)
Chronic2
- Mechanical trauma to the nasal mucosa increases the risk of synechia formation, especially after chronic rhinosinusitis and nasal surgeries. (propolisscience.org)
- Berger GKattan ABernheim JOphir D Polypoid mucosa with eosinophilia and glandular hyperplasia in chronic sinusitis: a histopathological and immunohistochemical study. (jamanetwork.com)
Epithelial cells obtained2
- Furthermore, the amount of TARC induced by these cytokines was higher in epithelial cells obtained from nasal allergy patients than in those from non-allergy patients. (nii.ac.jp)
- The present study evaluated the ultrastructure of epithelial cells obtained by nasal brushing in 11 allergic children with asthma, before and after staying in an environment free of allergens, usually implicated in the genesis of inflammatory events. (univr.it)
Cells8
- Hideaki Shirasaki, Etsuko Kanaizumi, Nobuhiko Seki, and Tetsuo Himi, "Correlation of Local FOXP3-Expressing T Cells and Th1-Th2 Balance in Perennial Allergic Nasal Mucosa," International Journal of Otolaryngology , vol. 2011, Article ID 259867, 6 pages, 2011. (hindawi.com)
- The proliferation and migration abilities of irradiated and non-irradiated nasal epithelial cells significantly increased after culture in bronchial epithelial cell growth medium (BEGM) containing 10% conditioned medium of hUC-MSCs compared to cells cultured in BEGM alone. (springer.com)
- These results demonstrate a crucial role of nasal epithelial cells in the expression of TARC, and that Th2 cytokine IL-4 and IL-13 may promote Th2 responses by inducing TARC production from epithelial cells. (nii.ac.jp)
- Nasal mucosa cells were harvested by brushing, a noninvasive procedure. (uniss.it)
- Degenerative lesions of nasal epithelial cells were found. (meta.org)
- The IgA secreted across the mucosa prevents microbial binding to epithelial cells in the digestive and respiratory tracts. (biomedcentral.com)
- It exists in two forms, that differ in the structure: IgA1 is found in serum and produced by bone marrow B cells, whereas IgA2 is made by B cells located in the mucosa and has been found to be secreted into colostrum, maternal milk, tears and saliva. (biomedcentral.com)
- To analyse potential differences in efficiency of infection and spread for different historical PRV strains, single infected cells and plaques of infected cells were quantified at 12 and 36 hpi in nasal mucosa explants for seven European PRV strains, isolated in the 1960s (Becker, NIA1), the 1970s (NS374, NIA3, 75V19) and later (89V87, 00V72). (uantwerpen.be)
Inferior nasal2
- It is also mentioned the role of the head of the inferior nasal concha in limiting the maximal airflow. (oatd.org)
- an accessory opening is frequently present above the posterior part of the inferior nasal concha. (wikipedia.org)
Bacterial3
- Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not adults. (nih.gov)
- A greater amount of bacterial IgA1 protease causes a confined impairment of the nasal mucosal immune barrier and may be a primary event in the pathogenesis of inflammatory respiratory disease [ 5 ]. (biomedcentral.com)
- Most of the bacterial and fungal causes are rare and usually affect other parts of the body as well as the nasal passages. (bmj.com)
Vascular2
- Immunoexpression of vascular endothelial growth factor in gingival mucosa with papilloma and condyloma acuminata. (semanticscholar.org)
- In order to explore this option we investigated what vascular structures could play a role in trans-migration by identifying the distribution of MECA-79, a adhesion molecule involved in transmigration, on nasal endothelium. (biomedcentral.com)
Formaldehyde1
- Occupational exposure to formaldehyde and histopathological changes in the nasal mucosa. (bmj.com)
Membrane2
- We are able to smell because our nasal membrane has nerves and receptors. (wisegeek.com)
- Different alphaherpesviruses, including pseudorabies virus (PRV), are able to cross the basement membrane barrier in nasal respiratory epithelium. (uantwerpen.be)
Lateral3
- Unexpectedly, a significant reduction in the expression of the Cyp2a5 gene was found in the liver, the lateral nasal gland (LNG), and, to a lesser extent, the kidney of adult Cyp2g1 -null mice. (aspetjournals.org)
- The superior meatus occupies the middle third of the nasal cavity's lateral wall. (wikipedia.org)
- It extends most of the length of the nasal cavity's lateral wall. (wikipedia.org)
Conclusions1
- Conclusions: Much has been written about the advantages of nasal snuff over products that deliver tobacco smoke. (elsevier.com)
Meatus2
- In the case where a fourth, supreme nasal concha is present, there is a fourth supreme nasal meatus . (wikipedia.org)
- The middle meatus is the middle-sized and located nasal opening, lying underneath the middle concha and above the inferior concha where the meatus extends along its length. (wikipedia.org)
Significantly3
- The findings from the present study suggest that PER is characterized by a significantly greater eosinophilic and predominantly Th2 cell-mediated nasal inflammatory profile compared to IAR. (wiley.com)
- IL-22−/− mice demonstrate significantly elevated levels of S. aureus nasal colonization as compared with wild-type (WT) mice. (tcd.ie)
- However, we found that noradrenergic fluorescent fibers were significantly decreased in the glandular region of the allergic nasal mucosa. (elsevier.com)
Staphylococcus2
Ulceration3
- Illustration shows gastric mucosa with influx of H. Pylori (upper left) leading to peptic ulceration. (indexedvisuals.com)
- Four men had perforated nasal septa and 2 others to have some degree of septal ulceration. (cdc.gov)
- As evidence of this, are the five individuals in whom injected nasal mucosa were noted and the 2 men with active septal ulceration. (cdc.gov)
Patients with nasal1
- Background: It is generally accepted that the parasympathetic nerve predominates in patients with nasal allergies. (elsevier.com)