Myocarditis
Coxsackievirus Infections
Enterovirus B, Human
Autoimmune Diseases
Myocardium
Cardiomyopathy, Dilated
Chagas Cardiomyopathy
Enterovirus
Encephalomyocarditis virus
Biopsy
Pericarditis
Myosins
Cardiomyopathies
Giant Cells
Edema, Cardiac
Disease Models, Animal
Trypanosoma cruzi
Parvovirus B19, Human
Fatal Serratia marcescens meningitis and myocarditis in a patient with an indwelling urinary catheter. (1/1509)
Serratia marcescens is commonly isolated from the urine of patients with an indwelling urinary catheter and in the absence of symptoms is often regarded as a contaminant. A case of fatal Serratia marcescens septicaemia with meningitis, brain abscesses, and myocarditis discovered at necropsy is described. The patient was an 83 year old man with an indwelling urinary catheter who suffered from several chronic medical conditions and from whose urine Serratia marcescens was isolated at the time of catheterisation. Serratia marcescens can be a virulent pathogen in particular groups of patients and when assessing its significance in catheter urine specimens, consideration should be given to recognised risk factors such as old age, previous antibiotic treatment, and underlying chronic or debilitating disease, even in the absence of clinical symptoms. (+info)Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis. (2/1509)
BACKGROUND: Previous studies dealing with the detection of enteroviral RNA in human endomyocardial biopsies have not differentiated between latent persistence of the enteroviral genome and active viral replication. Enteroviruses that are considered important factors for the development of myocarditis have a single-strand RNA genome of positive polarity that is transcribed by a virus-encoded RNA polymerase into a minus-strand mRNA during active viral replication. The synthesis of multiple copies of minus-strand enteroviral RNA therefore occurs only at sites of active viral replication but not in tissues with mere persistence of the viral genome. METHODS AND RESULTS: We investigated enteroviral RNA replication versus enteroviral RNA persistence in endomyocardial biopsies of 45 patients with left ventricular dysfunction and clinically suspected myocarditis. Using reverse-transcriptase polymerase chain reaction in conjunction with Southern blot hybridization, we established a highly sensitive assay to specifically detect plus-strand versus minus-strand enteroviral RNA in the biopsies. Plus-strand enteroviral RNA was detected in endomyocardial biopsies of 18 (40%) of 45 patients, whereas minus-strand RNA as an indication of active enteroviral RNA replication was detected in only 10 (56%) of these 18 plus-strand-positive patients. Enteroviral RNA was not found in biopsies of the control group (n=26). CONCLUSIONS: These data demonstrate that a significant fraction of patients with left ventricular dysfunction and clinically suspected myocarditis had active enteroviral RNA replication in their myocardium (22%). Differentiation between patients with active viral replication and latent viral persistence should be particularly important in future studies evaluating different therapeutic strategies. In addition, molecular genetic detection of enteroviral genome and differentiation between replicating versus persistent viruses is possible in a single endomyocardial biopsy. (+info)Chlamydia infections and heart disease linked through antigenic mimicry. (3/1509)
Chlamydia infections are epidemiologically linked to human heart disease. A peptide from the murine heart muscle-specific alpha myosin heavy chain that has sequence homology to the 60-kilodalton cysteine-rich outer membrane proteins of Chlamydia pneumoniae, C. psittaci, and C. trachomatis was shown to induce autoimmune inflammatory heart disease in mice. Injection of the homologous Chlamydia peptides into mice also induced perivascular inflammation, fibrotic changes, and blood vessel occlusion in the heart, as well as triggering T and B cell reactivity to the homologous endogenous heart muscle-specific peptide. Chlamydia DNA functioned as an adjuvant in the triggering of peptide-induced inflammatory heart disease. Infection with C. trachomatis led to the production of autoantibodies to heart muscle-specific epitopes. Thus, Chlamydia-mediated heart disease is induced by antigenic mimicry of a heart muscle-specific protein. (+info)From myocarditis to cardiomyopathy: mechanisms of inflammation and cell death: learning from the past for the future. (4/1509)
A progression from viral myocarditis to dilated cardiomyopathy has long been hypothesized, but the actual extent of this progression has been uncertain. However, a causal link between viral myocarditis and dilated cardiomyopathy has become more evident than before with the tremendous developments in the molecular analyses of autopsy and endomyocardial biopsy specimens, new techniques of viral gene amplification, and modern immunology. The persistence of viral RNA in the myocardium beyond 90 days after inoculation, confirmed by the method of polymerase chain reaction, has given us new insights into the pathogenesis of dilated cardiomyopathy. Moreover, new knowledge of T-cell-mediated immune responses in murine viral myocarditis has contributed a great deal to the understanding of the mechanisms of ongoing disease processes. Apoptotic cell death may provide the third concept to explain the pathogenesis of dilated cardiomyopathy, in addition to persistent viral RNA in the heart tissue and an immune system-mediated mechanism. Beneficial effects of alpha1-adrenergic blocking agents, carteolol, verapamil, and ACE inhibitors have been shown clinically and experimentally in the treatment of viral myocarditis and dilated cardiomyopathy. Antiviral agents should be more extensively investigated for clinical use. The rather discouraging results obtained to date with immunosuppressive agents in the treatment of viral myocarditis indicated the importance of sparing neutralizing antibody production, which may be controlled by B cells, and raised the possibility of promising developments in immunomodulating therapy. (+info)Global biventricular dysfunction in patients with asymptomatic coronary artery disease may be caused by myocarditis. (5/1509)
BACKGROUND: The causal role of asymptomatic critical coronary artery obstruction in patients presenting with severe global biventricular dysfunction but no evidence of myocardial infarction is uncertain. METHODS AND RESULTS: Among 291 patients aged >40 years undergoing a noninvasive (2-dimensional echocardiography) and invasive (catheterization, coronary angiography, and biventricular endomyocardial biopsy, 6 to 8 samples/patient) cardiac study because of progressive heart failure (New York Heart Association functional class III or IV) with global biventricular dysfunction and no history of myocardial ischemic events, 7 patients (2.4%; 7 men; mean age, 49+/-6.9 years) had severe coronary artery disease (3 vessels in 4 patients; 2 vessels in 1 patient, proximal occlusion of left anterior descending coronary artery in 2 patients). Left ventricular end-diastolic diameter and ejection fraction by 2-dimensional echocardiography were 73+/-10.5 mm and 23+/-6.5%, respectively, and right ventricular end-diastolic diameter and ejection fraction were 39+/-7 mm and 29+/-7.2%, respectively. Biopsy specimens showed extensive lymphocytic infiltrates with focal myocytolysis meeting the Dallas criteria for myocarditis in all patients (in 5 patients with and 2 patients without fibrosis). Cardiac autoantibodies were detected with indirect immunofluorescence in the serum of 2 patients with active myocarditis. The 2 patients with active inflammation received prednisone (1 mg. kg-1. d-1 for 4 weeks followed by 0.33 mg. kg-1. d-1 for 5 months) and azathioprine (2 mg. kg-1. d-1 for 5 months) in addition to conventional drug therapy for heart failure. At 8-month overall follow-up, cardiac volume and function improved considerably in immunosuppressed patients but remained unchanged in conventionally treated patients, of whom 1 died. CONCLUSIONS: Global biventricular dysfunction in patients with severe asymptomatic coronary artery disease and no evidence of previous myocardial infarction may be caused by myocarditis. Histologic findings may influence the treatment. (+info)Detection of adenoviral genome in the myocardium of adult patients with idiopathic left ventricular dysfunction. (6/1509)
BACKGROUND: The use of molecular biological techniques has demonstrated the importance of enteroviral infection of the myocardium in the pathogenesis of myocarditis and dilated cardiomyopathy in adults and adenovirus and enterovirus infection in children. The aim of this study was to determine the frequency of adenoviral infection of the myocardium of adults with impaired left ventricular function of unknown origin. METHODS AND RESULTS: Nested polymerase chain reaction (nPCR) was used to determine the frequency of detection of adenoviral DNA and enteroviral RNA in myocardial tissue samples from 94 adult patients with idiopathic left ventricular dysfunction and 14 control patients. Histological and immunohistological analyses were performed to detect myocardial inflammation. Adenoviral genomic DNA was detected by nPCR in 12 of the 94 patients with left ventricular dysfunction (in each case, adenovirus type 2), whereas enteroviral RNA was detected in another 12 patients. All control samples were negative for both viruses. In all patients, active myocarditis was excluded according to the Dallas criteria. However, there was significantly decreased CD2, CD3, and CD45RO T lymphocyte counts in the adenovirus-positive group compared with the adenovirus-negative group (P<0.05), whereas no differences were associated with enterovirus infection. CONCLUSIONS: Although enteroviruses are an important causative agent in the pathogenesis of myocarditis and dilated cardiomyopathy, this study shows that adenovirus infection is also important in the pathogenesis of left ventricular failure in adults. However, the pathogenetic basis of disease associated with adenovirus infection may be different than that after infection with other agents, particularly with respect to activation of the host immune response. (+info)A case of eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma. (7/1509)
This report describes a patient with eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma. A 50-year-old man presented with a complaint of precordial pain. However, the only abnormal finding on examinatioin was eosinophilia (1617 eosinophils/microl). Three years later, the patient developed chronic eczema, and was diagnosed with erythroderma posteczematosa. One year later, a tumor was detected in the right auricule, and a diagnosis of Kimura's disease was made, based on the biopsy findings. The patient developed progressive dyspnea 6 months later and was found to have cardiomegaly and a depressed left ventricular ejection fraction (17%). A diagnosis of eosinophilic myocarditis was made based on the results of a right ventricular endomyocardial biopsy. The eosinophilic myocarditis and erythrodrema were treated with steroids with improvement of both the eosinophilia and left ventricular function. (+info)Rheumatic chorea in northern Australia: a clinical and epidemiological study. (8/1509)
To describe the epidemiology and clinical features of Sydenham's chorea in the Aboriginal population of northern Australia a review was conducted of 158 episodes in 108 people: 106 were Aborigines, 79 were female, and the mean age was 10.9 years at first episode. Chorea occurred in 28% of cases of acute rheumatic fever, carditis occurred in 25% of episodes of chorea, and arthritis in 8%. Patients with carditis or arthritis tended to have raised acute phase reactants and streptococcal serology. Two episodes lasted at least 30 months. Mean time to first recurrence of chorea was 2.1 years compared with 1.2 years to second recurrence. Established rheumatic heart disease developed in 58% of cases and was more likely in those presenting with acute carditis, although most people who developed rheumatic heart disease did not have evidence of acute carditis with chorea. Differences in the patterns of chorea and other manifestations of acute rheumatic fever in different populations may hold clues to its pathogenesis. Long term adherence to secondary prophylaxis is crucial following all episodes of acute rheumatic fever, including chorea, to prevent recurrence. (+info)The symptoms of myocarditis can vary depending on the severity of the inflammation and the location of the affected areas of the heart muscle. Common symptoms include chest pain, shortness of breath, fatigue, and swelling in the legs and feet.
Myocarditis can be difficult to diagnose, as its symptoms are similar to those of other conditions such as coronary artery disease or heart failure. Diagnosis is typically made through a combination of physical examination, medical history, and results of diagnostic tests such as electrocardiogram (ECG), echocardiogram, and blood tests.
Treatment of myocarditis depends on the underlying cause and severity of the condition. Mild cases may require only rest and over-the-counter pain medication, while more severe cases may require hospitalization and intravenous medications to manage inflammation and cardiac function. In some cases, surgery may be necessary to repair or replace damaged heart tissue.
Prevention of myocarditis is important, as it can lead to serious complications such as heart failure and arrhythmias if left untreated. Prevention strategies include avoiding exposure to viruses and other infections, managing underlying medical conditions such as diabetes and high blood pressure, and getting regular check-ups with a healthcare provider to monitor cardiac function.
In summary, myocarditis is an inflammatory condition that affects the heart muscle, causing symptoms such as chest pain, shortness of breath, and fatigue. Diagnosis can be challenging, but treatment options range from rest and medication to hospitalization and surgery. Prevention is key to avoiding serious complications and maintaining good cardiac health.
Coxsackievirus infections are a group of viral diseases caused by enteroviruses, primarily Coxsackie A and B viruses. These infections can affect various parts of the body, including the gastrointestinal tract, skin, and nervous system.
Types of Coxsackievirus Infections:
1. Hand, Foot, and Mouth Disease (HFMD): This is a common viral illness that affects children under the age of 10, causing fever, mouth sores, and a rash with blisters on the hands and feet.
2. Herpangina: A severe form of HFMD characterized by small ulcers in the mouth and throat.
3. Aseptic Meningitis: An inflammation of the meninges (protective membranes) around the brain and spinal cord, often caused by Coxsackievirus B.
4. Myocarditis: Inflammation of the heart muscle caused by Coxsackievirus B.
5. Pericarditis: Inflammation of the membrane surrounding the heart (pericardium) caused by Coxsackievirus B.
6. Pleurodynia (also known as Coxsackievirus pleurisy): A sudden onset of chest pain, fever, and cough caused by Coxsackievirus A.
7. Meningoradiculitis: Inflammation of the meninges and spinal nerves caused by Coxsackievirus B.
Symptoms of Coxsackievirus Infections:
The symptoms of coxsackievirus infections can vary depending on the type of infection and the individual affected. Common symptoms include:
* Fever
* Headache
* Muscle pain
* Sore throat
* Mouth sores (in HFMD)
* Rash (in HFMD)
* Blisters (in HFMD)
* Seizures (in severe cases)
* Meningitis (inflammation of the membranes surrounding the brain and spinal cord)
* Encephalitis (inflammation of the brain)
* Myocarditis (inflammation of the heart muscle)
* Pericarditis (inflammation of the membrane surrounding the heart)
* Pleurodynia (chest pain, fever, and cough)
* Meningoradiculitis (inflammation of the meninges and spinal nerves)
Diagnosis of Coxsackievirus Infections:
The diagnosis of coxsackievirus infections is based on a combination of clinical features, laboratory tests, and imaging studies. Laboratory tests may include:
* Blood tests to detect the presence of antibodies against the virus
* PCR (polymerase chain reaction) to detect the genetic material of the virus in respiratory or gastrointestinal secretions
* Culture of the virus from respiratory or gastrointestinal secretions
* Imaging studies such as X-rays, CT scans, MRI scans to evaluate the extent of inflammation or damage to organs.
Treatment and Management of Coxsackievirus Infections:
There is no specific treatment for coxsackievirus infections, but supportive care may be provided to manage symptoms and prevent complications. Supportive care may include:
* Rest and hydration
* Pain management with over-the-counter pain medications or prescription medications
* Antihistamines to reduce fever and relieve itching
* Antiviral medications in severe cases
* Oxygen therapy if necessary
* Intravenous fluids if dehydration is present.
Prevention of Coxsackievirus Infections:
Prevention of coxsackievirus infections is important, especially for high-risk individuals such as children and people with weakened immune systems. Prevention measures include:
* Practicing good hygiene, such as washing hands frequently, especially after using the bathroom or before eating
* Avoiding close contact with people who are sick
* Avoiding sharing food, drinks, or personal items with people who are sick
* Keeping children home from school or daycare if they are experiencing symptoms of a coxsackievirus infection
* Practicing safe sex to prevent the spread of the virus through sexual contact.
Complications of Coxsackievirus Infections:
Coxsackievirus infections can lead to complications, especially in high-risk individuals. Complications may include:
* Meningitis or encephalitis, which can be life-threatening
* Myocarditis, which can lead to heart failure
* Pericarditis, which can cause chest pain and difficulty breathing
* Retinitis, which can cause blindness
* Gastrointestinal bleeding
* Kidney damage or failure.
Prognosis for Coxsackievirus Infections:
The prognosis for coxsackievirus infections is generally good for most people, especially those with mild symptoms. However, high-risk individuals, such as children and people with weakened immune systems, may experience more severe illness and have a poorer prognosis.
Prevention of Coxsackievirus Infections:
Prevention is key to avoiding coxsackievirus infections. Some ways to prevent the spread of the virus include:
* Practicing good hygiene, such as washing your hands frequently and avoiding sharing personal items with people who are sick
* Avoiding close contact with people who are sick
* Keeping children home from school or daycare if they are experiencing symptoms of a coxsackievirus infection
* Practicing safe sex to prevent the spread of the virus through sexual contact.
Treatment of Coxsackievirus Infections:
There is no specific treatment for coxsackievirus infections, but symptoms can be managed with over-the-counter medications and home remedies. Some ways to manage symptoms include:
* Taking over-the-counter pain relievers, such as acetaminophen or ibuprofen, to reduce fever and relieve headache and body aches
* Drinking plenty of fluids to stay hydrated
* Resting and avoiding strenuous activities until symptoms improve
* Using a humidifier to relieve dryness and discomfort in the throat and nose.
Complications of Coxsackievirus Infections:
Coxsackievirus infections can lead to complications, such as:
* Meningitis: an inflammation of the protective membranes that cover the brain and spinal cord
* Encephalitis: an inflammation of the brain
* Myocarditis: an inflammation of the heart muscle
* Pericarditis: an inflammation of the membrane surrounding the heart
* Pleurodynia: a painful inflammation of the lining of the chest cavity.
It's important to seek medical attention if you or your child experiences any of these complications, as they can be serious and potentially life-threatening.
Conclusion:
Coxsackievirus infections are common and can cause a range of symptoms, from mild to severe. Prevention is key, and taking steps such as washing your hands frequently, avoiding close contact with people who are sick, and keeping children home from school or daycare when they are ill can help reduce the risk of transmission. If you suspect that you or your child has a coxsackievirus infection, it's important to seek medical attention if symptoms worsen or if complications develop. With prompt and appropriate treatment, most people with coxsackievirus infections recover fully.
Examples of autoimmune diseases include:
1. Rheumatoid arthritis (RA): A condition where the immune system attacks the joints, leading to inflammation, pain, and joint damage.
2. Lupus: A condition where the immune system attacks various body parts, including the skin, joints, and organs.
3. Hashimoto's thyroiditis: A condition where the immune system attacks the thyroid gland, leading to hypothyroidism.
4. Multiple sclerosis (MS): A condition where the immune system attacks the protective covering of nerve fibers in the central nervous system, leading to communication problems between the brain and the rest of the body.
5. Type 1 diabetes: A condition where the immune system attacks the insulin-producing cells in the pancreas, leading to high blood sugar levels.
6. Guillain-Barré syndrome: A condition where the immune system attacks the nerves, leading to muscle weakness and paralysis.
7. Psoriasis: A condition where the immune system attacks the skin, leading to red, scaly patches.
8. Crohn's disease and ulcerative colitis: Conditions where the immune system attacks the digestive tract, leading to inflammation and damage to the gut.
9. Sjögren's syndrome: A condition where the immune system attacks the glands that produce tears and saliva, leading to dry eyes and mouth.
10. Vasculitis: A condition where the immune system attacks the blood vessels, leading to inflammation and damage to the blood vessels.
The symptoms of autoimmune diseases vary depending on the specific disease and the organs or tissues affected. Common symptoms include fatigue, fever, joint pain, skin rashes, and swollen lymph nodes. Treatment for autoimmune diseases typically involves medication to suppress the immune system and reduce inflammation, as well as lifestyle changes such as dietary changes and stress management techniques.
The most common symptoms of enterovirus infections include:
* Diarrhea
* Vomiting
* Fever
* Abdominal pain
* Headache
* Fatigue
In some cases, enterovirus infections can lead to more severe complications, such as:
* Hand, foot, and mouth disease (HFMD)
* Aseptic meningitis
* Encephalitis
* Myocarditis
Enteroviruses are highly contagious and can be spread through:
* Close contact with an infected person
* Contaminated food and water
* Insect vectors
There is no specific treatment for enterovirus infections, but symptoms can be managed with supportive care, such as hydration, rest, and pain relief. Antiviral medications may be used in severe cases.
Prevention measures include:
* Good hygiene practices, such as frequent handwashing
* Avoiding close contact with people who are sick
* Properly preparing and storing food and water
* Avoiding sharing items that come into contact with the mouth, such as utensils and drinking glasses.
There are several possible causes of dilated cardiomyopathy, including:
1. Coronary artery disease: This is the most common cause of dilated cardiomyopathy, and it occurs when the coronary arteries become narrowed or blocked, leading to a decrease in blood flow to the heart muscle.
2. High blood pressure: Prolonged high blood pressure can cause the heart muscle to become weakened and enlarged.
3. Heart valve disease: Dysfunctional heart valves can lead to an increased workload on the heart, which can cause dilated cardiomyopathy.
4. Congenital heart defects: Some congenital heart defects can lead to an enlarged heart and dilated cardiomyopathy.
5. Alcohol abuse: Chronic alcohol abuse can damage the heart muscle and lead to dilated cardiomyopathy.
6. Viral infections: Some viral infections, such as myocarditis, can cause inflammation of the heart muscle and lead to dilated cardiomyopathy.
7. Genetic disorders: Certain genetic disorders, such as hypertrophic cardiomyopathy, can cause dilated cardiomyopathy.
8. Obesity: Obesity is a risk factor for developing dilated cardiomyopathy, particularly in younger people.
9. Diabetes: Diabetes can increase the risk of developing dilated cardiomyopathy, especially if left untreated or poorly controlled.
10. Age: Dilated cardiomyopathy is more common in older adults, with the majority of cases occurring in people over the age of 65.
It's important to note that many people with these risk factors will not develop dilated cardiomyopathy, and some people without any known risk factors can still develop the condition. If you suspect you or someone you know may have dilated cardiomyopathy, it's important to consult a healthcare professional for proper diagnosis and treatment.
Chagas cardiomyopathy is a type of heart disease that is caused by the parasitic infection Trypanosoma cruzi, which is transmitted through the feces of infected triatomine bugs. It is also known as American trypanosomiasis or Latin American trypanosomiasis.
The infection can cause inflammation and damage to the heart muscle, leading to cardiomyopathy, which is a condition where the heart muscle becomes weakened and cannot pump blood effectively. This can lead to symptoms such as shortness of breath, fatigue, swelling, and irregular heartbeat.
Chagas cardiomyopathy is most commonly found in countries in Central and South America, where the disease is transmitted by triatomine bugs that are found in rural areas. It is estimated that around 8 million people are infected with Chagas disease worldwide, with the majority of cases occurring in Latin America.
There is no cure for Chagas cardiomyopathy, but medications and other treatments can help manage symptoms and slow the progression of the disease. Prevention is key to avoiding Chagas cardiomyopathy, and this includes avoiding triatomine bug bites, using insecticides to kill bugs in homes, and screening blood donors for the disease.
Overall, Chagas cardiomyopathy is a serious and debilitating condition that can have significant implications for quality of life and survival. It is important to be aware of the risk of infection and take steps to prevent it, particularly if you live in or travel to areas where the disease is common.
Examples of acute diseases include:
1. Common cold and flu
2. Pneumonia and bronchitis
3. Appendicitis and other abdominal emergencies
4. Heart attacks and strokes
5. Asthma attacks and allergic reactions
6. Skin infections and cellulitis
7. Urinary tract infections
8. Sinusitis and meningitis
9. Gastroenteritis and food poisoning
10. Sprains, strains, and fractures.
Acute diseases can be treated effectively with antibiotics, medications, or other therapies. However, if left untreated, they can lead to chronic conditions or complications that may require long-term care. Therefore, it is important to seek medical attention promptly if symptoms persist or worsen over time.
Cardiovirus infections are a type of viral infection that affects the heart muscle, leading to cardiomyopathy and potentially heart failure. The most common cause of cardiovirus infections is the adenovirus, which is a common virus that can infect people of all ages.
Symptoms of Cardiovirus Infections:
The symptoms of cardiovirus infections can vary depending on the severity of the infection and the individual's overall health. Common symptoms include:
* Chest pain or discomfort
* Shortness of breath
* Fatigue
* Swelling of the legs, ankles, and feet
* Fast or irregular heartbeat
* Low blood pressure
Diagnosis of Cardiovirus Infections:
To diagnose a cardiovirus infection, a healthcare provider will typically perform a physical examination and ask about the individual's symptoms. They may also order one or more diagnostic tests, such as:
* Electrocardiogram (ECG) to measure the heart's electrical activity
* Echocardiogram to visualize the heart and its function
* Blood tests to look for signs of inflammation or cardiac damage
Treatment of Cardiovirus Infections:
There is no specific treatment for cardiovirus infections, but the following treatments may be recommended to manage symptoms and prevent complications:
* Rest and avoiding strenuous activities
* Medications to control heart rate and rhythm
* Diuretics to reduce fluid buildup in the body
* Oxygen therapy to improve oxygen levels in the blood
Prevention of Cardiovirus Infections:
Preventing cardiovirus infections is challenging, but taking steps to avoid exposure can help reduce the risk. These steps include:
* Practicing good hygiene, such as washing hands frequently and avoiding close contact with people who are sick
* Avoiding sharing food, drinks, or personal items with people who are sick
* Covering the mouth and nose when coughing or sneezing
* Staying home from work or school if experiencing symptoms
It is important to note that cardiovirus infections can be severe and potentially life-threatening, especially for certain populations such as older adults, young children, and people with underlying heart conditions. If you suspect you or someone else may have a cardiovirus infection, it is essential to seek medical attention right away.
The common types of reoviridae infections include:
1. Rotavirus infection: This is the most common cause of diarrhea in children under five years old worldwide. It can lead to dehydration, hospitalization, and even death in severe cases.
2. Calicivirus infection: This virus is responsible for norovirus, which is the leading cause of gastroenteritis outbreaks in the United States and other countries. It can cause symptoms such as diarrhea, vomiting, and stomach cramps.
3. Aichivirus infection: This virus was first identified in 2013 and has been linked to outbreaks of gastroenteritis in the United States and Europe. The symptoms of this infection are similar to those caused by norovirus.
4. Cysticercosis: This is a parasitic infection that occurs when the larvae of the pork tapeworm (Taenia solium) infect the human brain, eyes, or muscles. It can cause symptoms such as seizures, headaches, and vision problems.
5. Orbivirus infection: This virus is responsible for diseases such as bluetongue and epizootic hemorrhagic fever, which affects animals such as sheep, goats, and cattle. It can also be transmitted to humans through the bite of an infected midge insect.
Reoviridae infections are usually diagnosed based on symptoms, medical history, and laboratory tests such as PCR (polymerase chain reaction) or ELISA (enzyme-linked immunosorbent assay). Treatment of these infections depends on the specific type of virus and the severity of the symptoms.
Prevention measures for Reoviridae infections include good hygiene practices such as washing hands regularly, cooking food thoroughly, and avoiding close contact with people who are sick. Vaccines are also available for some types of Reoviridae infections, such as the rotavirus vaccine that is given to infants to protect against gastroenteritis.
Pericarditis is diagnosed through a combination of physical examination, medical history, and diagnostic tests such as electrocardiogram (ECG), echocardiogram, or blood tests. Treatment for pericarditis usually involves antibiotics if the condition is caused by an infection, as well as medication to manage pain and inflammation. In severe cases, surgery may be necessary to drain fluid from the pericardium or repair any damage to the heart muscle.
Pericarditis can have long-term effects on the heart if left untreated, such as scarring or thickening of the pericardium, which can lead to chronic inflammation and impaired heart function. Therefore, prompt diagnosis and treatment are important to prevent complications and improve outcomes for patients with pericarditis.
1. Common cold: A viral infection that affects the upper respiratory tract and causes symptoms such as sneezing, running nose, coughing, and mild fever.
2. Influenza (flu): A viral infection that can cause severe respiratory illness, including pneumonia, bronchitis, and sinus and ear infections.
3. Measles: A highly contagious viral infection that causes fever, rashes, coughing, and redness of the eyes.
4. Rubella (German measles): A mild viral infection that can cause fever, rashes, headache, and swollen lymph nodes.
5. Chickenpox: A highly contagious viral infection that causes fever, itching, and a characteristic rash of small blisters on the skin.
6. Herpes simplex virus (HSV): A viral infection that can cause genital herpes, cold sores, or other skin lesions.
7. Human immunodeficiency virus (HIV): A viral infection that attacks the immune system and can lead to acquired immunodeficiency syndrome (AIDS).
8. Hepatitis B: A viral infection that affects the liver, causing inflammation and damage to liver cells.
9. Hepatitis C: Another viral infection that affects the liver, often leading to chronic liver disease and liver cancer.
10. Ebola: A deadly viral infection that causes fever, vomiting, diarrhea, and internal bleeding.
11. SARS (severe acute respiratory syndrome): A viral infection that can cause severe respiratory illness, including pneumonia and respiratory failure.
12. West Nile virus: A viral infection that can cause fever, headache, and muscle pain, as well as more severe symptoms such as meningitis or encephalitis.
Viral infections can be spread through contact with an infected person or contaminated surfaces, objects, or insects such as mosquitoes. Prevention strategies include:
1. Practicing good hygiene, such as washing hands frequently and thoroughly.
2. Avoiding close contact with people who are sick.
3. Covering the mouth and nose when coughing or sneezing.
4. Avoiding sharing personal items such as towels or utensils.
5. Using condoms or other barrier methods during sexual activity.
6. Getting vaccinated against certain viral infections, such as HPV and hepatitis B.
7. Using insect repellents to prevent mosquito bites.
8. Screening blood products and organs for certain viruses before transfusion or transplantation.
Treatment for viral infections depends on the specific virus and the severity of the illness. Antiviral medications may be used to reduce the replication of the virus and alleviate symptoms. In severe cases, hospitalization may be necessary to provide supportive care such as intravenous fluids, oxygen therapy, or mechanical ventilation.
Prevention is key in avoiding viral infections, so taking the necessary precautions and practicing good hygiene can go a long way in protecting oneself and others from these common and potentially debilitating illnesses.
There are several types of cardiomyopathies, each with distinct characteristics and symptoms. Some of the most common forms of cardiomyopathy include:
1. Hypertrophic cardiomyopathy (HCM): This is the most common form of cardiomyopathy and is characterized by an abnormal thickening of the heart muscle, particularly in the left ventricle. HCM can lead to obstruction of the left ventricular outflow tract and can increase the risk of sudden death.
2. Dilated cardiomyopathy: This type of cardiomyopathy is characterized by a decrease in the heart's ability to pump blood effectively, leading to enlargement of the heart and potentially life-threatening complications such as congestive heart failure.
3. Restrictive cardiomyopathy: This type of cardiomyopathy is characterized by stiffness of the heart muscle, which makes it difficult for the heart to fill with blood. This can lead to shortness of breath and fatigue.
4. Left ventricular non-compaction (LVNC): This is a rare type of cardiomyopathy that occurs when the left ventricle does not properly compact, leading to reduced cardiac function and potentially life-threatening complications.
5. Cardiac amyloidosis: This is a condition in which abnormal proteins accumulate in the heart tissue, leading to stiffness and impaired cardiac function.
6. Right ventricular cardiomyopathy (RVCM): This type of cardiomyopathy is characterized by impaired function of the right ventricle, which can lead to complications such as pulmonary hypertension and heart failure.
7. Endocardial fibroelastoma: This is a rare type of cardiomyopathy that occurs when abnormal tissue grows on the inner lining of the heart, leading to reduced cardiac function and potentially life-threatening complications.
8. Cardiac sarcoidosis: This is a condition in which inflammatory cells accumulate in the heart, leading to impaired cardiac function and potentially life-threatening complications.
9. Hypertrophic cardiomyopathy (HCM): This is a condition in which the heart muscle thickens, leading to reduced cardiac function and potentially life-threatening complications such as arrhythmias and sudden death.
10. Hypokinetic left ventricular cardiomyopathy: This type of cardiomyopathy is characterized by decreased contraction of the left ventricle, leading to reduced cardiac function and potentially life-threatening complications such as heart failure.
It's important to note that some of these types of cardiomyopathy are more common in certain populations, such as hypertrophic cardiomyopathy being more common in young athletes. Additionally, some types of cardiomyopathy may have overlapping symptoms or co-occurring conditions, so it's important to work with a healthcare provider for an accurate diagnosis and appropriate treatment.
A condition characterized by swelling of the heart and surrounding tissues due to an accumulation of fluid. This can occur as a result of various conditions such as heart failure, coronary artery disease, or cardiomyopathy. The swelling can lead to symptoms such as shortness of breath, fatigue, and difficulty exercising. Treatment options include diuretics, ACE inhibitors, and other medications to manage the underlying condition causing the edema.
Example sentence: "The patient was diagnosed with cardiac edema and started on a regimen of diuretics and ACE inhibitors to help reduce the swelling and improve their symptoms."
1) They share similarities with humans: Many animal species share similar biological and physiological characteristics with humans, making them useful for studying human diseases. For example, mice and rats are often used to study diseases such as diabetes, heart disease, and cancer because they have similar metabolic and cardiovascular systems to humans.
2) They can be genetically manipulated: Animal disease models can be genetically engineered to develop specific diseases or to model human genetic disorders. This allows researchers to study the progression of the disease and test potential treatments in a controlled environment.
3) They can be used to test drugs and therapies: Before new drugs or therapies are tested in humans, they are often first tested in animal models of disease. This allows researchers to assess the safety and efficacy of the treatment before moving on to human clinical trials.
4) They can provide insights into disease mechanisms: Studying disease models in animals can provide valuable insights into the underlying mechanisms of a particular disease. This information can then be used to develop new treatments or improve existing ones.
5) Reduces the need for human testing: Using animal disease models reduces the need for human testing, which can be time-consuming, expensive, and ethically challenging. However, it is important to note that animal models are not perfect substitutes for human subjects, and results obtained from animal studies may not always translate to humans.
6) They can be used to study infectious diseases: Animal disease models can be used to study infectious diseases such as HIV, TB, and malaria. These models allow researchers to understand how the disease is transmitted, how it progresses, and how it responds to treatment.
7) They can be used to study complex diseases: Animal disease models can be used to study complex diseases such as cancer, diabetes, and heart disease. These models allow researchers to understand the underlying mechanisms of the disease and test potential treatments.
8) They are cost-effective: Animal disease models are often less expensive than human clinical trials, making them a cost-effective way to conduct research.
9) They can be used to study drug delivery: Animal disease models can be used to study drug delivery and pharmacokinetics, which is important for developing new drugs and drug delivery systems.
10) They can be used to study aging: Animal disease models can be used to study the aging process and age-related diseases such as Alzheimer's and Parkinson's. This allows researchers to understand how aging contributes to disease and develop potential treatments.
Myocarditis
Eosinophilic myocarditis
Idiopathic giant-cell myocarditis
Cardiac muscle
Bornholm disease
COVID-19 vaccine
Galloway v. United States
Acute eosinophilic leukemia
SCAR-Fc
Anti-mitochondrial antibody
1924 Los Angeles pneumonic plague outbreak
Cardiac rhythm problems during spaceflight
Sarnoff Fellowship
Complications of hypertension
Infectious mononucleosis
Alphonso Davies
Lisa Hopp
Latrodectus elegans
Embryocardia
Deaths in May 2001
Mephedrone
Brucella
Latrodectus
Synaptic stabilization
Foot-and-mouth disease
Myopericarditis
Enterovirus
Mumps
Manfred Green
Coxsackie B virus
Myocarditis and Pericarditis After mRNA COVID-19 Vaccination | CDC
Myocarditis: MedlinePlus Medical Encyclopedia
Myocarditis: MedlinePlus Medical Encyclopedia
Myocarditis Guidelines: Guidelines Summary
Meeting the Challenges of Myocarditis Workshop | NHLBI, NIH
Does the COVID-19 vaccine cause myocarditis? - HealthyChildren.org
Browsing by Subject "Myocarditis"
First Close Look at Presumed Myocarditis Cases After COVID Vaccination | MedPage Today
Myocarditis - Health Library | NewYork-Presbyterian
Myocarditis - PubMed
Myocarditis pathophysiology - wikidoc
COVID-19 vaccine benefits 'clearly' outweigh risks of rare myocarditis in teens, CDC says | Live Science
The effects of gender and age on occurrence of clinically suspected myocarditis in adulthood
Bayern Munich's Alphonso Davies experiencing myocarditis after 'Covid infection' (INJECTION) - David Icke
Myocarditis and methyldopa - PubMed
COVID-19 vaccine: Myocarditis and pericarditis study | Ministry of Health NZ
Study: SARS-CoV-2 Vaccination and Myocarditis | Australian Vaccination-risks Network Inc.
Myocarditis and Immunosuppression in Inflammatory Bowel Disease
Myocarditis Outbreak among Adults, Illinois, 2003 - Volume 11, Number 10-October 2005 - Emerging Infectious Diseases journal -...
Trending Clinical Topic: Myocarditis
No Myocarditis Recurrence After SARS-CoV-2 Vaccination - Physician's Weekly
Calcium overload in human giant cell myocarditis. | Journal of Clinical Pathology
Symptoms of Myocarditis: 12 to Know | The Healthy @Reader's Digest
Myocarditis after Covid-19 Vaccination in a Large Health Care Organization - ABIFINA
2023 FEB 15 Dr Melissa McCann reveals Vax Induced Myocarditis Wilful Concealment by Skerritt and TGA
C-reactive protein: An early critical sign of clozapine-related myocarditis<...
Congestive heart failure and cytomegaloviral myocarditis in an im | 56930
Ep. 290: Young Mom Charity Hospitalized 6X with Myocarditis- Why the Vax Injured Are "In Denial" - GreenSmoothieGirl
Vaccinated Young Adults 18-24 Are 41-44 Times More Likely To Be Afflicted With Myocarditis Than Unvaccinated
Acute myocarditis9
- Refine clinically meaningful subtypes of patients with acute myocarditis through integration of state-of-the-art immunological analysis of biospecimens linked to deep phenotyping of diverse clinical cohorts. (nih.gov)
- The first case series described eight patients from the U.S. and Italy who presented with chest pain and were diagnosed with acute myocarditis at an average of 3 days after getting an mRNA vaccine. (medpagetoday.com)
- Panel A shows acute myocarditis with widespread lymphocytic and histiocytic infiltrate (arrow) and associated myocyte damage (arrowhead) (hematoxylin and eosin). (nih.gov)
- Panel B shows CD3 immunostaining of T lymphocytes in a patient with acute myocarditis. (nih.gov)
- Acute myocarditis is characterized by inflammatory infiltrates of the myocardium. (cdc.gov)
- Acute myocarditis is typically sporadic, although clusters have been reported during outbreaks of viral disease ( 2 , 3 ). (cdc.gov)
- Iyad Abou Saleh, M.D., from Hospices Civils de Lyon in France, and colleagues enrolled 142 patients with a prior history of confirmed acute myocarditis to examine the risk of myocarditis recurrence following SARS-CoV-2 vaccination. (physiciansweekly.com)
- We showed that SARS-CoV-2 vaccination in patients with a history of acute myocarditis is not associated with a risk of recurrent myocarditis or other serious side effects," Abou Saleh said in a statement. (physiciansweekly.com)
- This case reaffirms the possibility of cardiac involvement in CMV infection and emphasizes the importance of viral etiologies as differential diagnoses for acute myocarditis. (longdom.org)
Pericarditis14
- CDC and its partners are actively monitoring reports of myocarditis and pericarditis after COVID-19 vaccination. (cdc.gov)
- Most patients with myocarditis or pericarditis who received care responded well to medicine and rest and felt better quickly. (cdc.gov)
- Seek medical care if you or your child have any of the specific or general symptoms of myocarditis or pericarditis especially if it's within a week after COVID-19 vaccination. (cdc.gov)
- The known risks of COVID-19 illness and its related, possibly severe complications, such as long-term health problems, hospitalization, and even death, far outweigh the potential risks of having a rare adverse reaction to vaccination, including the possible risk of myocarditis or pericarditis. (cdc.gov)
- A study has been launched to find out if people who developed myocarditis or pericarditis following COVID-19 Pfizer vaccination had long-term health problems. (health.govt.nz)
- Anyone over 12, with a clinical diagnosis of myocarditis or pericarditis following a Pfizer vaccination, is eligible to participate. (health.govt.nz)
- International data suggests that for most people who develop myocarditis and/or pericarditis, their symptoms stop with appropriate management. (health.govt.nz)
- Anyone who experienced myocarditis or pericarditis after their COVID-19 vaccine and has not yet reported this can submit a CARM report at any time. (health.govt.nz)
- This is so we can ask for information about medications prescribed and test results so we can get a better understanding of your/their health following myocarditis and/or pericarditis. (health.govt.nz)
- In the future, health researchers may want to contact participants about follow-up research on health, or health services, relating to myocarditis and pericarditis. (health.govt.nz)
- Results of this large cohort study indicated that both first and second doses of mRNA vaccines were associated with increased risk of myocarditis and pericarditis. (avn.org.au)
- On March 21, 2003, the Kane County Health Department was notified about 6 cases of presumptive myocarditis and 1 case of pericarditis that occurred in patients hospitalized in Kane County, Illinois, within a 2-week period from February 26 to March 10. (cdc.gov)
- It is important for people to know about myocarditis, as it is often mistaken for other heart conditions, including pericarditis, heart disease, and heart attack," he says. (thehealthy.com)
- Another new study indicates the rate of myocarditis or pericarditis is 1 in 3,339 for males 18 to 24 receiving 2 doses of the Moderna vaccine, and it is 1 in 6,262 for males 12 to 17. (notrickszone.com)
Giant cell myocarditis4
- The guidelines also discuss four major myocarditis subtypes that result in a fulminant presentation (fulminant lymphocytic myocarditis, giant cell myocarditis, acute necrotizing eosinophilic myocarditis, immune checkpoint inhibitor myocarditis), along with their microscopic findings (hematoxylin/eosin stain), clinical manifestations, and treatment. (medscape.com)
- less commonly, specific forms of myocarditis may result from other pathogens, toxic or hypersensitivity drug reactions, giant-cell myocarditis, or sarcoidosis. (nih.gov)
- Calcium overload in human giant cell myocarditis. (bmj.com)
- Myocardial calcium overload was observed in a patient with giant cell myocarditis. (bmj.com)
Reports of myocarditis2
- And in the clinical trials of more than 3,000 children age 5 to 11, there were no reports of myocarditis from the vaccine. (healthychildren.org)
- The investigators also conducted a systematic literature review on case reports of myocarditis in patients with IBD (n=83) using OvidSP and PubMed databases. (clinicaladvisor.com)
Consistent with myocarditis3
- Lab and imaging findings were largely consistent with myocarditis. (medpagetoday.com)
- As in the other reports, the 52-year-old previously healthy man developed chest pain days after being vaccinated with the second dose of the Moderna vaccine and had clinical and cardiac MRI findings consistent with myocarditis. (medpagetoday.com)
- Even so, the MRI scans, taken 11-53 days after completion of quarantine, showed four of the student athletes (all males) had swelling and tissue damage to their hearts consistent with myocarditis. (nih.gov)
Cardiac10
- and lessons learned from cardiac immunology for application to myocarditis research. (nih.gov)
- Potential mechanisms for myocarditis post-mRNA-based vaccination include a non-specific innate inflammatory response or a molecular mimicry mechanism between viral spike protein and an unknown cardiac protein," Larson and colleagues noted. (medpagetoday.com)
- Our series of seven male COVID-19 vaccination recipients who presented with myocarditis-like illness supports a potential causal association with vaccination given the temporal relationship, clinical presentation and CMR [cardiac MRI] findings," deFilippi's team wrote. (medpagetoday.com)
- The cardiac manifestations of COVID range far beyond myocarditis. (medscape.com)
- Given the myriad of cardiac concerns associated with SARS-CoV-2 infection, news that the myocarditis associated with mRNA vaccination is mostly mild and resolves quickly in the rare instances in which it occurs was welcome news. (medscape.com)
- But while those can be a few symptoms of a heart attack, they may also indicate a rarer condition called myocarditis-especially if those cardiac symptoms are accompanied by cold and flu symptoms. (thehealthy.com)
- There's a lot we still don't understand about the connection, but what we do know is that the COVID virus can cause several cardiac complications including myocarditis and heart failure syndromes," says Dr. Haythe. (thehealthy.com)
- In the presented research, a case of myocarditis and cardiac insufficiency due to primary CMV infection was reported. (longdom.org)
- Many cases of myocarditis are associated with autoimmune processes in which cardiac myosin is a major autoantigen. (nih.gov)
- Herein, using a well-established mouse model of experimental autoimmune myocarditis (EAM) induced by immunization against cardiac myosin resulting in T cell-mediated inflammation, cardiomyocyte cell death, fibrosis and myocardial dysfunction, we studied the potential beneficial effects of CBD. (nih.gov)
Develop myocarditis2
- Most patients who develop myocarditis after Covid vaccination respond well to medicine and recover fully, according the CDC. (cnbc.com)
- After the host immune system eliminates the viral genomes from the body, the immune system may remains activated in patients who develop myocarditis. (wikidoc.org)
Higher risk of developing2
Likely to cause myocarditis2
- In fact, becoming infected with COVID-19 itself is much more likely to cause myocarditis than the vaccine. (healthychildren.org)
- However, COVID-19 illness is far more likely to cause myocarditis than are the vaccines. (nih.gov)
Vaccines12
- Healthcare Providers: For additional recommendations and clinical guidance, visit Clinical Considerations: Myocarditis after mRNA COVID-19 Vaccines . (cdc.gov)
- Myocarditis had not been reported in clinical trials leading to the authorization of these vaccines. (medpagetoday.com)
- Myocarditis emerging after inoculation was not limited to the mRNA vaccines, according to a report from two U.S. centers . (medpagetoday.com)
- As of June 11, the CDC's vaccine adverse event reporting system logged 323 confirmed U.S. cases of heart muscle inflammation, or myocarditis, shortly after receipt of COVID-19 mRNA vaccines in people ages 12 to 29, Dr. Tom Shimabukuro, deputy director of the CDC's Immunization Safety Office, said during the meeting. (livescience.com)
- One of the more surprising findings to come out of the ongoing research into the COVID-19 pandemic is how both the SARS-CoV-2 virus and, to a lesser extent, the vaccines , can increase the risk of myocarditis. (thehealthy.com)
- Reports have suggested an association between the development of myocarditis and the receipt of messenger RNA (mRNA) vaccines against coronavirus disease 2019 (Covid-19), but the frequency and severity of myocarditis after vaccination have not been extensively explored. (abifina.org.br)
- Ever since the COVID vaccines became available to the younger age groups, physicians have begun reporting much higher rates of myocarditis among the vaccinated. (notrickszone.com)
- By January, 2022, one year after the vaccines became available, there were already over 1,000 peer-reviewed scientific papers reporting on mRNA vaccine-induced injuries like myocarditis. (notrickszone.com)
- Heart inflammation, or myocarditis, has been reported as a very rare side effect of COVID-19 vaccines. (nih.gov)
- COVID-19 is more likely than vaccines to cause myocarditis, and symptoms and outcomes are often worse. (nih.gov)
- We spoke with Fleg about the risk of myocarditis linked with COVID-19 illness and with vaccines. (nih.gov)
- Myocarditis has been linked with other vaccines, such as those that prevent influenza (flu), smallpox, and shingles. (nih.gov)
SARS-CoV-2 Vaccination1
- TUESDAY, March 22, 2022 (HealthDay News) - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination seems safe for patients with prior history of myocarditis, with no evidence of recurrence, according to a study presented at ESC Acute CardioVascular Care 2022, held virtually from March 18 to 19. (physiciansweekly.com)
Vaccine14
- The risk of myocarditis among men ages 18 to 39 is about 1.5 times higher after a second Moderna dose than with Pfizer's vaccine. (cnbc.com)
- Does the COVID-19 vaccine cause myocarditis? (healthychildren.org)
- Very rarely, myocarditis also has occurred in some people who have received the vaccine. (healthychildren.org)
- In the clinical trials studying the vaccine in kids 12 to 17 years, a small number of adolescents and young adults experienced mild cases of myocarditis after getting the COVID-19 vaccine. (healthychildren.org)
- And overall, this side effect appears rare - data so far show the rate of myocarditis following COVID-19 vaccine in people ages 12 to 39 is 12.6 cases per 1 million people vaccinated. (livescience.com)
- Data available to date suggest a likely association of myocarditis with mRNA vaccination in adolescents and young adults," Dr. Grace M. Lee, chair of the COVID-19 Vaccine Safety Technical Subgroup of the CDC's Advisory Committee on Immunization Practices (ACIP), said during the meeting. (livescience.com)
- Still, the data showed a clear benefit of the vaccine compared with the risk of myocarditis for all age groups. (livescience.com)
- Conclusions from the study continued… " For individuals receiving 2 doses of the same vaccine, risk of myocarditis was highest among young males (aged 16-24 years) after the second dose. (avn.org.au)
- These data suggest that most cases of suspected COVID-19 vaccine-related myocarditis in people younger than 21 are mild and resolve quickly," corresponding author Dongngan Truong, MD, said in a statement. (medscape.com)
- Fear of myocarditis recurrence was the main reason for not getting the vaccine (75 percent of unvaccinated patients). (physiciansweekly.com)
- The rates of vaccine-associated myocarditis are reported to be as high as 1 in 5,900 second doses. (notrickszone.com)
- 1 The most intensive safety monitoring system in U.S. history has made it possible to detect even very rare COVID-19 vaccine side effects, including myocarditis, which is inflammation of the heart muscle. (nih.gov)
- Men and boys between the ages of 16 and 29 have been most often affected by COVID-19-vaccine-related myocarditis, usually a few days after their second dose. (nih.gov)
- 5 Myocarditis may be due to their strong immune response to the vaccine. (nih.gov)
Symptoms8
- Myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu. (nih.gov)
- Contact your provider if you have symptoms of myocarditis, especially after a recent infection. (nih.gov)
- Mild myocarditis can involve symptoms such as chest pain or shortness of breath, or even no symptoms. (nih.gov)
- Myocarditis may present with a wide range of symptoms, ranging from mild dyspnea or chest pain that resolves without specific therapy to cardiogenic shock and death. (nih.gov)
- But even these patients might still consider receiving their second shot after they've recovered from their myocarditis symptoms under certain circumstances, Oliver said. (livescience.com)
- Two MDs share the symptoms of myocarditis you should know. (thehealthy.com)
- This is largely due to the fact that myocarditis symptoms can vary from person to person and be caused by many different things-in fact, 90% of cases are "idiopathic," meaning they have no known origin, he adds. (thehealthy.com)
- Note: Some people with myocarditis may not have any symptoms at all, and the condition may only be discovered during routine testing or evaluation for other medical conditions. (thehealthy.com)
Rate of myocarditis1
- Still, for young males, the rate is higher, up to 66 cases per 1 million people, Shimabukuro said, which is much higher than the background rate of myocarditis cases that would be expected in the short period of time after vaccination for this age group. (livescience.com)
Causes of myocarditis1
- In addition, new causes of myocarditis, such as side effects of cancer therapies, are emerging. (nih.gov)
Diagnosis of myocarditis1
- Conclusions: Current protocols monitoring for myocarditis have their limitations and can often only be used to support a presumptive diagnosis of myocarditis. (monash.edu)
Vaccination and myocarditis1
- None of these reports were able to definitively confirm or exclude a causal relationship between vaccination and myocarditis. (medpagetoday.com)
Infection8
- Compared to the potential risks of COVID-19 infection in kids, myocarditis appears to be quite rare. (healthychildren.org)
- In fact, children are more at risk of myocarditis after multisystem inflammatory syndrome, a serious illness from COVID-19 infection. (healthychildren.org)
- Alphonso Davies has signs of a slight myocarditis after his corona infection. (davidicke.com)
- An infectious cause of myocarditis is usually suspected when unexplained heart failure or arrhythmia occurs in a person with a systemic febrile illness or upper respiratory tract infection. (cdc.gov)
- Myocarditis has been an ongoing concern during the pandemic because it has been associated with COVID-19 infection and, to a much lesser degree, with vaccination. (medscape.com)
- During the COVID-19 pandemic, Fleg turned his attention to the effects of SARS-CoV-2 infection on the heart, including myocarditis. (nih.gov)
- It's clear that vaccination can protect you from myocarditis by protecting you from COVID-19 infection. (nih.gov)
- Myocarditis is an uncommon complication of SARS-CoV-2 infection. (nih.gov)
Covid9
- Detailed records showed that people diagnosed with myocarditis after COVID-19 vaccination tended to be men, and all were able to recover after a few days in the hospital. (medpagetoday.com)
- While it would be irresponsible to say if the myocarditis was definitely brought upon by COVID-19, the condition has been listed among the side effects of the virus. (davidicke.com)
- The CDC has found that patients with COVID-19 have nearly 16 times the risk for myocarditis. (medscape.com)
- An interesting new study in the journal JAMA Cardiology provides valuable and rather worrisome early data from COVID-positive student athletes evaluated for an inflammation of the heart called myocarditis, a well-known complication [1]. (nih.gov)
- Viral infections, including COVID-19, are most often the cause, 2 but other diseases, as well as some drugs and toxins, can also cause myocarditis. (nih.gov)
- Can COVID-19 cause myocarditis? (nih.gov)
- We don't know exactly how often this happens, but one study estimated that myocarditis affects about 40 people out of every 1,000,000 people who test positive for COVID-19. (nih.gov)
- 3 However, myocarditis is much more common in patients hospitalized for COVID-19 (226 per 100,000). (nih.gov)
- Getting vaccinated to prevent severe COVID-19 cuts your risk of myocarditis. (nih.gov)
Clinical7
- Examine the roles of integrated endomyocardial biopsy, imaging, laboratory, and clinical criteria in revised diagnostic categories to improve the management of myocarditis. (nih.gov)
- Use a standardized clinical and imaging platform in prospective multicenter imaging-based trials that establishes the role of imaging and biopsy to identify new biomarkers for myocarditis diagnosis and prognostication. (nih.gov)
- The prognosis and treatment of myocarditis vary according to the cause, and clinical and hemodynamic data usually provide guidance to decide when to refer a patient to a specialist for endomyocardial biopsy. (nih.gov)
- Investigators sought to determine the clinical characteristics of patients with both myocarditis and IBD. (clinicaladvisor.com)
- At myocarditis diagnosis, there were 74% with IBD activity, 58% with infarct-like myocarditis presentation, 8% with subacute course, and 92% with clinical resolution. (clinicaladvisor.com)
- Among patients with concomitant IBD and myocarditis, the investigators concluded that myocarditis in IBD usually follows a benign clinical course. (clinicaladvisor.com)
- Trending Clinical Topic: Myocarditis - Medscape - Dec 17, 2021. (medscape.com)
Myocardial3
- Endomyocardial biopsy was negative in the single case in which it was performed, though this may be explained by the patchy nature of myocardial inflammation in myocarditis, said Christopher deFilippi, MD, of Inova Heart and Vascular Institute in Falls Church, Virginia, and colleagues. (medpagetoday.com)
- Reports with a diagnosis of EMB-proven or clinically suspected myocarditis (according to the 2013 ESC Working Group of Myocardial and Pericardial diseases), a diagnosis of IBD (according to the 2018 European Crohn's and Colitis Organization Criteria), and with at least echocardiographic and/or demographical or cardiovascular magnetic resonance imaging data at the moment of myocarditis diagnosis were included. (clinicaladvisor.com)
- 96.4 percent were vaccinated with BNT162b2 (53 patients) and one each was vaccinated with mRNA-1273 and Ad26.COV2-S. There were no cases of death/myocardial infarction/stroke and no cases of myocarditis observed after vaccination. (physiciansweekly.com)
Dengue myocarditis3
- Dengue Myocarditis: A Case Report and Major Review. (bvsalud.org)
- Dengue myocarditis is considered an uncommon complication of dengue , although its reported incidence is likely an underestimation. (bvsalud.org)
- In general, most cases of dengue myocarditis are self -limited, with only a minority at risk of progressing to heart failure . (bvsalud.org)
Cardiomyopathy5
- Dilated cardiomyopathy with chronic heart failure is the major long-term sequela of myocarditis. (nih.gov)
- A review of all records for patients with discharge diagnoses of myocarditis or cardiomyopathy at all 5 hospitals in Kane County from October 1, 2002, through March 31, 2003, was conducted to find unreported cases of myocarditis. (cdc.gov)
- 2] Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities: Task Force 3: Hypertrophic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy and other cardiomyopathies, and myocarditis . (nih.gov)
- Myocarditis, Cardiomyopathy and Mitral Valve Incompetence: Can be fatal. (nih.gov)
- Myocarditis and related disorders: proceedings of the International Symposium on Cardiomyopathy and Myocarditis / edited by Morie Sekiguchi, Eckhardt G. J. Olsen, John F. Goodwin. (who.int)
Inflammation of the myocardium1
- Myocarditis is defined as an inflammation of the myocardium based on histological findings. (nih.gov)
Pfizer2
- Public health authorities in Canada found the risk of myocarditis in men ages 18- to 24-years-old was lower when they waited eight weeks for the second dose of Moderna or Pfizer. (cnbc.com)
- Men in this age group report about 68 myocarditis cases per 1 million Moderna second doses administered, compared with 47 myocarditis cases per 1 million Pfizer second doses administered. (cnbc.com)
Autoimmune3
- Dr. Haythe says myocarditis can also be caused by bacterial or fungal infections , autoimmune diseases , exposure to toxins, chest trauma, and adverse reactions to certain medications. (thehealthy.com)
- Conventional immunosuppressive therapies are often provide unsatisfactory results and are associated with adverse toxicities during the treatment of autoimmune myocarditis. (nih.gov)
- Thus, CBD may represent a promising new treatment for management of autoimmune myocarditis. (nih.gov)
Chest5
- If the provider suspects myocarditis based on the exam and chest x-ray, an electrocardiogram may also be done to help make the diagnosis. (nih.gov)
- You have been diagnosed with myocarditis, and you have increased chest pain , swelling , or breathing problems . (nih.gov)
- In the majority of cases it [myocarditis] affects young males, presenting with infarct-like chest pain at the time of an IBD flare," the study authors wrote. (clinicaladvisor.com)
- Pain in the chest -often described as pressure or squeezing-is the most common symptom of myocarditis, says Dr. Haythe. (thehealthy.com)
- Severe problems linked with myocarditis include chest pain, arrhythmias , trouble breathing, ankle or leg swelling, and fainting. (nih.gov)
Clinically1
- Study limitations include potential selection bias in the review of literature, and the majority of patients had a clinically suspected myocarditis diagnosis. (clinicaladvisor.com)
Eosinophilic1
- Eosinophilic and hypersensitive myocarditis may occur secondary to parasitic infections , drug hypersensitivity or hypereosinophilic syndrome . (wikidoc.org)
Fulminant1
- The scientific statement on recognition and initial management of fulminant myocarditis (FM) was released in January 2020 by the American Heart Association (AHA). (medscape.com)
Endomyocardial1
- Patients with suspected myocarditis or myocarditis diagnosed via endomyocardial biopsy (EMB) that succeeded, preceded, or was concomitant with IBD diagnosis were included. (clinicaladvisor.com)
Risk5
- Treat conditions that cause myocarditis promptly to reduce the risk. (nih.gov)
- Public health authorities in Canada found that the risk of myocarditis is lower for younger men when they wait eight weeks. (cnbc.com)
- The risk of myocarditis is low after vaccination. (cnbc.com)
- Young men are especially at risk for acquiring myocarditis, while women are affected most commonly at the postmenopausal age. (nih.gov)
- According to the Centers for Disease Control and Prevention (CDC), myocarditis after mRNA vaccination occurs after 70 per 1 million doses given among boys aged 16-17 years, who are at highest risk. (medscape.com)
Abstract1
- abstract = "Objective: We present a case of clozapine-related myocarditis, with a rising C-reactive protein as the only initial evidence supporting the diagnosis. (monash.edu)
Pediatric1
- The condition is called pediatric myocarditis when it occurs in children. (nih.gov)
Severe3
- However, significant morbidity and mortality are associated with severe myocarditis, particularly in children and young adults. (nih.gov)
- Although myocarditis often resolves on its own over time, severe cases can compromise the heart muscle's ability to beat. (nih.gov)
- For more severe cases of myocarditis caused by a virus, such as SARS-CoV-2, people may need to stay in the hospital for a week or two - often in the ICU. (nih.gov)
Second dose2
- Myocarditis most commonly occurs after viral infections, but the CDC has also found a link with between Moderna's and Pfizer's shots and myocarditis, particularly after the second dose. (cnbc.com)
- Preliminary recommendations from the CDC, which may be updated before they are finalized, say that people who experience myocarditis after the first dose should defer their second dose until more information is known, Oliver said. (livescience.com)
Dose1
- But experts stressed the need for further follow-up of these patients to evaluate the potential long-term risks of myocarditis, and to figure out how to handle cases of myocarditis that happen after the first dose. (livescience.com)
Uncommon2
Hepatitis1
- Fatal methyldopa-associated granulomatous hepatitis and myocarditis. (nih.gov)
Illness1
- Finally, the detailed case of a man with myocarditis-like illness after vaccination revealed a lack of the expected cytokine changes implicated in myocarditis. (medpagetoday.com)
Cause inflammation1
- But in some people, that virus will cause inflammation of the heart muscle, and that's myocarditis," he explains. (thehealthy.com)
Heart10
- Myocarditis is inflammation of the heart muscle. (cdc.gov)
- Those who have been diagnosed with myocarditis should consult with their cardiologist (heart doctor) about return to exercise or sports. (cdc.gov)
- Myocarditis is an inflammation of the heart muscle than can result in serious health problems, according to the National Heart, Lung and Blood Institute. (cnbc.com)
- Myocarditis is an inflammation of the heart muscle. (healthychildren.org)
- Myocarditis is a rare heart condition, affecting only one to 100 people out of 100,000 each year in the US, according to John Hopkins University. (thehealthy.com)
- Myocarditis is the medical condition when the heart muscle (called the "myocardium") becomes inflamed. (thehealthy.com)
- The patient was diagnosed with heart failure due to CMV myocarditis. (longdom.org)
- Myocarditis is an inflammation of the heart that may lead to irregular heart rhythms and a reduction in the heart's capacity to pump blood. (notrickszone.com)
- Myocarditis is a major cause of heart failure and sudden death in young adults and adolescent. (nih.gov)
- Myocarditis usually goes away on its own with supportive care, including IV fluids, steroid therapy, and medicines to treat disorders of heart rhythm or pumping function. (nih.gov)