The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
The circulation of blood through the CORONARY VESSELS of the HEART.
Treatment process involving the injection of fluid into an organ or tissue.
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Tomography using single-photon emitting RADIONUCLIDES to create images that are captured in times corresponding to various points in the cardiac cycle.
The hollow, muscular organ that maintains the circulation of the blood.
The creation and display of functional images showing where the blood flow reaches by following the distribution of tracers injected into the blood stream.
Radionuclide ventriculography where scintigraphic data is acquired during repeated cardiac cycles at specific times in the cycle, using an electrocardiographic synchronizer or gating device. Analysis of right ventricular function is difficult with this technique; that is best evaluated by first-pass ventriculography (VENTRICULOGRAPHY, FIRST-PASS).
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Unstable isotopes of rubidium that decay or disintegrate emitting radiation. Rb atoms with atomic weights 79-84, and 86-95 are radioactive rubidium isotopes.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
Organic compounds that contain phosphorus as an integral part of the molecule. Included under this heading is broad array of synthetic compounds that are used as PESTICIDES and DRUGS.
Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter.
Substances used to allow enhanced visualization of tissues.
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Tomography using radioactive emissions from injected RADIONUCLIDES and computer ALGORITHMS to reconstruct an image.
Drugs used to cause dilation of the blood vessels.
Any visible result of a procedure which is caused by the procedure itself and not by the entity being analyzed. Common examples include histological structures introduced by tissue processing, radiographic images of structures that are not naturally present in living tissue, and products of chemical reactions that occur during analysis.
The veins and arteries of the HEART.
The ratio of maximum blood flow to the MYOCARDIUM with CORONARY STENOSIS present, to the maximum equivalent blood flow without stenosis. The measurement is commonly used to verify borderline stenosis of CORONARY ARTERIES.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Radionuclide ventriculography where a bolus of radionuclide is injected and data are recorded from one pass through the heart ventricle. Left and right ventricular function can be analyzed independently during this technique. First-pass ventriculography is preferred over GATED BLOOD-POOL IMAGING for assessing right ventricular function.
The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.
Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
An imaging technique using compounds labelled with short-lived positron-emitting radionuclides (such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18) to measure cell metabolism. It has been useful in study of soft tissues such as CANCER; CARDIOVASCULAR SYSTEM; and brain. SINGLE-PHOTON EMISSION-COMPUTED TOMOGRAPHY is closely related to positron emission tomography, but uses isotopes with longer half-lives and resolution is lower.
Narrowing or constriction of a coronary artery.
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.
A method of recording heart motion and internal structures by combining ultrasonic imaging with exercise testing (EXERCISE TEST) or pharmacologic stress.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.
Isotopes that exhibit radioactivity and undergo radioactive decay. (From Grant & Hackh's Chemical Dictionary, 5th ed & McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
The span of viability of a tissue or an organ.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
The flow of BLOOD through or around an organ or region of the body.
The measurement of visualization by radiation of any organ after a radionuclide has been injected into its blood supply. It is used to diagnose heart, liver, lung, and other diseases and to measure the function of those organs, except renography, for which RADIOISOTOPE RENOGRAPHY is available.
Tellurium. An element that is a member of the chalcogen family. It has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.
Small uniformly-sized spherical particles, of micrometer dimensions, frequently labeled with radioisotopes or various reagents acting as tags or markers.
Elements of limited time intervals, contributing to particular results or situations.
Freedom from activity.
Electronic instruments that produce photographs or cathode-ray tube images of the gamma-ray emissions from organs containing radionuclide tracers.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.
Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
A colorless alkaline gas. It is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Note that the aqueous form of ammonia is referred to as AMMONIUM HYDROXIDE.
Combination or superimposition of two images for demonstrating differences between them (e.g., radiograph with contrast vs. one without, radionuclide images using different radionuclides, radiograph vs. radionuclide image) and in the preparation of audiovisual materials (e.g., offsetting identical images, coloring of vessels in angiograms).
A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds in a pharmaceutical form.
The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, atomic number 43, and atomic weight 98.91. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.
Pathological conditions involving the HEART including its structural and functional abnormalities.
ANGINA PECTORIS or angina-like chest pain with a normal coronary arteriogram and positive EXERCISE TEST. The cause of the syndrome is unknown. While its recognition is of clinical importance, its prognosis is excellent. (Braunwald, Heart Disease, 4th ed, p1346; Jablonski Dictionary of Syndromes & Eponymic Diseases, 2d ed). It is different from METABOLIC SYNDROME X, a syndrome characterized by INSULIN RESISTANCE and HYPERINSULINEMIA, that has increased risk for cardiovascular disease.
Pressure, burning, or numbness in the chest.
Liquid perfluorinated carbon compounds which may or may not contain a hetero atom such as nitrogen, oxygen or sulfur, but do not contain another halogen or hydrogen atom. This concept includes fluorocarbon emulsions and fluorocarbon blood substitutes.
A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Devices or objects in various imaging techniques used to visualize or enhance visualization by simulating conditions encountered in the procedure. Phantoms are used very often in procedures employing or measuring x-irradiation or radioactive material to evaluate performance. Phantoms often have properties similar to human tissue. Water demonstrates absorbing properties similar to normal tissue, hence water-filled phantoms are used to map radiation levels. Phantoms are used also as teaching aids to simulate real conditions with x-ray or ultrasonic machines. (From Iturralde, Dictionary and Handbook of Nuclear Medicine and Clinical Imaging, 1990)
Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity.
Contractile activity of the MYOCARDIUM.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
Hospital department responsible for the administration and management of nuclear medicine services.
Unstable isotopes of fluorine that decay or disintegrate emitting radiation. F atoms with atomic weights 17, 18, and 20-22 are radioactive fluorine isotopes.
Neoplasm drug therapy involving an extracorporeal circuit with temporary exclusion of the tumor-bearing area from the general circulation during which high concentrations of the drug are perfused to the isolated part.
Timing the acquisition of imaging data to specific points in the cardiac cycle to minimize image blurring and other motion artifacts.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
Separation systems containing a relatively long-lived parent radionuclide which produces a short-lived daughter in its decay scheme. The daughter can be periodically extracted (milked) by means of an appropriate eluting agent.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Types of spiral computed tomography technology in which multiple slices of data are acquired simultaneously improving the resolution over single slice acquisition technology.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Markedly reduced or absent REPERFUSION in an infarct zone following the removal of an obstruction or constriction of an artery.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
A class of compounds of the type R-M, where a C atom is joined directly to any other element except H, C, N, O, F, Cl, Br, I, or At. (Grant & Hackh's Chemical Dictionary, 5th ed)
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Diseases that do not exhibit symptoms.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Delivery of drugs into an artery.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures.
The circulation of blood through the BLOOD VESSELS of the BRAIN.
Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.
A form of heart block in which the electrical stimulation of HEART VENTRICLES is interrupted at either one of the branches of BUNDLE OF HIS thus preventing the simultaneous depolarization of the two ventricles.
Compounds that selectively bind to and activate ADENOSINE A2 RECEPTORS.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Water-soluble proteins found in egg whites, blood, lymph, and other tissues and fluids. They coagulate upon heating.
Examinations used to diagnose and treat heart conditions.
Radioactive substances added in minute amounts to the reacting elements or compounds in a chemical process and traced through the process by appropriate detection methods, e.g., Geiger counter. Compounds containing tracers are often said to be tagged or labeled. (Hawley's Condensed Chemical Dictionary, 12th ed)
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
A technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure. It may be achieved by intra-aortic balloon, or by implanting a special pumping device in the chest, or externally by applying a negative pressure to the lower extremities during cardiac systole.
A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
Computer systems or networks designed to provide radiographic interpretive information.
Irreversible cessation of all bodily functions, manifested by absence of spontaneous breathing and total loss of cardiovascular and cerebral functions.
Genetically developed small pigs for use in biomedical research. There are several strains - Yucatan miniature, Sinclair miniature, and Minnesota miniature.
A plant species of the family POLYGONACEAE. Itadori tea is prepared from the root of this genus.
Positive test results in subjects who do not possess the attribute for which the test is conducted. The labeling of healthy persons as diseased when screening in the detection of disease. (Last, A Dictionary of Epidemiology, 2d ed)
The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.
Computer programs based on knowledge developed from consultation with experts on a problem, and the processing and/or formalizing of this knowledge using these programs in such a manner that the problems may be solved.
The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.
The physiological widening of BLOOD VESSELS by relaxing the underlying VASCULAR SMOOTH MUSCLE.
Small encapsulated gas bubbles (diameters of micrometers) that can be used as CONTRAST MEDIA, and in other diagnostic and therapeutic applications. Upon exposure to sufficiently intense ultrasound, microbubbles will cavitate, rupture, disappear, release gas content. Such characteristics of the microbubbles can be used to enhance diagnostic tests, dissolve blood clots, and deliver drugs or genes for therapy.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
Imaging of a ventricle of the heart after the injection of a radioactive contrast medium. The technique is less invasive than cardiac catheterization and is used to assess ventricular function.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
VASCULAR DISEASES that are associated with DIABETES MELLITUS.
The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)
The study of the heart, its physiology, and its functions.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
The posture of an individual lying face down.
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
A method of producing a high-quality scan by digitizing and subtracting the images produced by high- and low-energy x-rays.
The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).
The minute vessels that connect the arterioles and venules.
The ratio of alveolar ventilation to simultaneous alveolar capillary blood flow in any part of the lung. (Stedman, 25th ed)
The unfavorable effect of environmental factors (stressors) on the physiological functions of an organism. Prolonged unresolved physiological stress can affect HOMEOSTASIS of the organism, and may lead to damaging or pathological conditions.
Radiography of blood vessels after injection of a contrast medium.
The long-term (minutes to hours) administration of a fluid into the vein through venipuncture, either by letting the fluid flow by gravity or by pumping it.
A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
The innermost layer of the heart, comprised of endothelial cells.
An isoenzyme of creatine kinase found in the CARDIAC MUSCLE.
The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346)
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
The hemodynamic and electrophysiological action of the HEART VENTRICLES.
Gadolinium. An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.
A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
Establishment of the level of a quantifiable effect indicative of a biologic process. The evaluation is frequently to detect the degree of toxic or therapeutic effect.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE.
A method of non-invasive, continuous measurement of MICROCIRCULATION. The technique is based on the values of the DOPPLER EFFECT of low-power laser light scattered randomly by static structures and moving tissue particulates.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
A non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiological procedures.
A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.
Improvement in the quality of an x-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed.
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
A condition in which HEART VENTRICLES exhibit impaired function.
Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included.
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
A noble gas with the atomic symbol Xe, atomic number 54, and atomic weight 131.30. It is found in the earth's atmosphere and has been used as an anesthetic.
Molecules which contain an atom or a group of atoms exhibiting an unpaired electron spin that can be detected by electron spin resonance spectroscopy and can be bonded to another molecule. (McGraw-Hill Dictionary of Chemical and Technical Terms, 4th ed)
An effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
The condition of an anatomical structure's being dilated beyond normal dimensions.
A type of MAGNETIC RESONANCE IMAGING that uses only one nuclear spin excitation per image and therefore can obtain images in a fraction of a second rather than the minutes required in traditional MRI techniques. It is used in a variety of medical and scientific applications.
Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh's Chemical Dictionary, 5th ed)
The condition of an anatomical structure's being constricted beyond normal dimensions.
Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
Disease having a short and relatively severe course.
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
The posture of an individual lying face up.
The use of combination of imaging techniques or platforms (e.g., MRI SCAN and PET SCAN) encompassing aspects of anatomical, functional, or molecular imaging methods.
Triiodo-substituted derivatives of BENZOIC ACID.

Predicting breast attenuation in patients undergoing myocardial perfusion scintigraphy: a digital x-ray study. (1/557)

Attenuation artifacts are the most common sources of error in myocardial single-photon emission computed tomography (SPECT) imaging. Breast artifacts are the most frequent causes of false positive planar images in female subjects. The purpose of this study was to predict breast adverse attenuation by measuring breast tissue thickness with digital x-ray. Sixty-five consecutive female patients with angina pectoris, who were referred to myocardial perfusion scintigraphy were enrolled in this study. Eighteen patients with normal perfusion imaging and normal coronary angiography composed the first group, whereas the second group consisted of 28 patients with a positive exercise electrocardiogram with anterior ischemia on myocardial perfusion imaging and greater than 50% left anterior descending artery stenosis on angiography. Nineteen patients in the third group had normal exercise electrocardiograms and normal coronary angiographies, but anterior ischemia on perfusion imaging. Digital x-ray records were obtained for measuring breast tissue thickness and Hounsfield density. The rate of breast adverse attenuation was 40% (19/47) in patients with anterior ischemia. The sensitivity and specificity of the prediction of breast adverse attenuation (lateral density less than 550 Hounsfield) were 79% and 11%, respectively. When breast attenuation for a breast thickness greater than 6 cm measured in the left anterior oblique view was predicted, the sensitivity and specificity were 79% and 93%, respectively. In conclusion, breast thickness greater than 6 cm measured from the left anterior oblique view with digital x-ray can predict breast adverse attenuation in female patients, and thereby may decrease the number of unnecessary invasive diagnostic procedures to be performed.  (+info)

Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging. (2/557)

PURPOSE: To compare left ventricular (LV) dyssynchrony assessment by phase analysis from gated myocardial perfusion SPECT (GMPS) with LV dyssynchrony assessment by tri-plane tissue Doppler imaging (TDI). Baseline LV dyssynchrony assessed with standard deviation (SD) of time-to-peak systolic velocity of 12 LV segments (Ts-SD) with TDI has proven to be a powerful predictor of response to CRT. Information on LV dyssynchrony can also be provided by GMPS with phase analysis of regional LV maximal count changes throughout the cardiac cycle. METHODS: Forty heart failure patients, referred for evaluation of potential eligibility for CRT, underwent both 3D echocardiography, with tri-plane TDI, and resting GMPS. From tri-plane TDI, Ts-SD was used as a validated parameter of LV dyssynchrony and compared with different indices (histogram bandwidth, phase SD, histogram skewness and kurtosis) derived from phase analysis of GMPS. RESULTS: Histogram bandwidth and phase SD showed good correlation with Ts-SD (r=0.77 and r=0.74, p<0.0001, respectively). Patients with substantial LV dyssynchrony assessed with tri-plane TDI (Ts-SD >or=33 ms) had also significantly higher values of histogram bandwidth and phase SD. CONCLUSIONS: The results of this study support the use of phase analysis by GMPS to evaluate LV dyssynchrony. Histogram bandwidth and phase SD showed the best correlation with Ts-SD assessed with tri-plane TDI and appeared the most optimal variables for assessment of LV dyssynchrony with GMPS.  (+info)

(99m)Tc-sestamibi uptake in rat skeletal muscle and heart: physiological determinants and correlations. (3/557)

The lipophilic cationic radiotracer (99m)Tc-sestamibi, known to be concentrated within mitochondria, is widely used for myocardial perfusion and to a lesser extent for muscle metabolism imaging. However, the exact distribution pattern in skeletal muscle has not been yet studied in detail. The present study aims to investigate the (99m)Tc-sestamibi uptake in rat skeletal muscle and myocardium in relation to their metabolic characteristics. (99m)Tc-sestamibi was i.v. administered in twenty adult male Wistar rats and uptake, as percent of injected dose per tissue gram (%ID/g), in the myocardium, soleus, extensor digitorum longus and gastrocnemius muscles was assessed 2 h after the injection. Muscle uptake was also correlated with myocardial uptake, muscle weight and body weight. Skeletal muscle (99m)Tc-sestamibi uptake was a small (9-16 %) fraction of that found in myocardium (1.71+/-0.63 %ID/g). Among the three hindlimb muscles considered, the slow-oxidative soleus muscle showed the highest uptake (0.28+/-0.16 %ID/g). Metabolically diverse parts of the gastrocnemius muscle showed different uptake. Skeletal muscle uptake was positively correlated with myocardial uptake and both were negatively correlated with tissue and body weight. Skeletal muscle and myocardium (99m)Tc-sestamibi uptake is related to their metabolic profile. Myocardium, with an exceptional rich mitochondrial concentration, shows much higher (99m)Tc-sestamibi uptake compared to skeletal muscles. Among muscles, uptake is dependent on their mitochondrial content. Evidence of matching exists between myocardial and muscle uptake, and both are size-dependent.  (+info)

Direct comparison between pharmacological stress with adenosine triphosphate disodium and exercise stress myocardial perfusion imagings. (4/557)

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High spatial resolution myocardial perfusion cardiac magnetic resonance for the detection of coronary artery disease. (5/557)

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Low-flow perfusion of guinea pig isolated hearts with 26 degrees C air-saturated Lifor solution for 20 hours preserves function and metabolism. (6/557)

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Semi-automated analysis of dynamic changes in myocardial contrast from real-time three-dimensional echocardiographic images as a basis for volumetric quantification of myocardial perfusion. (7/557)

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Recurrent myocardial infarction in a young football player with antithrombin III deficiency. (8/557)

Acute myocardial infarction is a rare condition in young athletes. One of the causes could be a hypercoagulable state due to congenital antithrombin III deficiency, together with a prothrombotic state soon after strenuous physical training. We present the case of myocardial reinfarction in young football player with antithrombin III deficiency, treated with primary percutaneous coronary intervention and drug eluting stent, as well as the functional repercussions of continuous intensive physical activity.  (+info)

A myocardial perfusion scan is a type of nuclear medicine procedure. This means that a tiny amount of a radioactive substance, called a radionuclide (radiopharmaceutical or radioactive tracer), is used during the procedure to assist in the examination of the tissue under study. Specifically, the myocardial perfusion scan evaluates the hearts function and blood flow.. A radionuclide is a radioactive substance used as a tracer, which means it travels through the blood stream and is taken up (absorbed) by the healthy heart muscle tissue. On the scan, the areas where the radionuclide has been absorbed will show up differently than the areas that do not absorb it (due to possible damage to the tissue from decreased or blocked blood flow).. A stress myocardial perfusion scan is used to assess the blood flow to the heart muscle (myocardium) when it is stressed by exercise or medication and to determine what areas of the myocardium have decreased blood flow. This is done by injecting a radionuclide ...
A myocardial perfusion scan is a type of nuclear medicine procedure. This means that a tiny amount of a radioactive substance, called a radionuclide (radiopharmaceutical or radioactive tracer), is used during the procedure to assist in the examination of the tissue under study. Specifically, the myocardial perfusion scan evaluates the hearts function and blood flow.. A radionuclide is a radioactive substance used as a tracer, which means it travels through the blood stream and is taken up (absorbed) by the healthy heart muscle tissue. On the scan, the areas where the radionuclide has been absorbed will show up differently than the areas that do not absorb it (due to possible damage to the tissue from decreased or blocked blood flow).. A resting myocardial perfusion scan is used to assess the blood flow to the heart muscle (myocardium) and to determine what areas of the myocardium have decreased blood flow. This is done by injecting a radionuclide (thallium or technetium) into a vein in the ...
Background-The clinical analysis of myocardial dynamic computed tomography myocardial perfusion imaging lacks standardization. The objective of this prospective study was to compare different analysis approaches to diagnose ischemia in patients with stable angina referred for invasive coronary angiography. Methods and Results-Patients referred for evaluation of stable angina symptoms underwent adenosine-stress dynamic computed tomography myocardial perfusion imaging with a second-generation dual-source scanner. Quantitative perfusion parameters, such as blood flow, were calculated by parametric deconvolution for each myocardial voxel. Initially, perfusion parameters were extracted according to standard 17-segment model of the left ventricle (fully automatic analysis). These were then manually sampled by an operator (semiautomatic analysis). Areas under the receiver-operating characteristic curves of the 2 different approaches were compared. Invasive fractional flow reserve ≤0.80 or diameter ...
A myocardial perfusion scan is a test to evaluate blood flow and contraction of your heart muscle. A radioactive material called a radio-tracer is injected through a vein into your bloodstream. The radio-tracer then locates in your heart muscle in proportion to the amount of coronary blood flow. The radio-tracer produces gamma rays that a gamma camera detects and uses to produce images. Myocardial perfusion scanning has good track record and is a safe way of evaluating your heart. For cardiac testing we use the following radio-tracers: thallium-201, technetium-99m sestamibi (Cardiolite®), and technetium-99m tetrofosmin (Myoview™). These radio-tracers expose the body to a very small amount of radiation. No long-term effects have been reported from these doses. We use these tracer as they are taken up into the myocardium (or heart muscle) as you can see in the image.. For a myocardial perfusion scan we take two sets of images (two separate scans), one while the heart is more active (stress ...
Learn how much a Nuclear Stress Test (Myocardial Perfusion Scan) costs in Valparaiso, Indiana. Get the best price for a Nuclear Stress Test (Myocardial Perfusion Scan) with MDsave.
MINNEAPOLIS, July 13, 2015-- Vital Images, Inc. will debut its 510 FDA- cleared CT Myocardial Perfusion application at the 10 th Annual Scientific Meeting of the Society of Cardiovascular Computed Tomography in Las Vegas, July 16-19.. Vital s CT Myocardial Perfusion was developed using feedback gathered from industry experts who also participated in the CORE...
Whilst the CTCA scan and coronary angiogram give anatomical information about the coronary arteries and any possible narrowing, Myocardial Perfusion Scanning (MPS, Myoview, Thallium scan) looks at the functional uptake of blood by the heart muscle and by implication the coronary blood supply to the heart. This is achieved by exercising the heart either with physical exercise (eg treadmill or exercise bike) or in some situations by using a drug infusion to increase the heart rate.. In Myocardial Perfusion Scans a small dose of a radioisotope is injected into a vein and images of the heart are observed using a special scanner (gamma camera) following exercise stress and at rest. The basic principle of the test is to look at whether tracer uptake is reduced in the stress image which can suggest limitation in blood supply to the heart and the possible need for further tests. A further useful function of myocardial perfusion scanning is in planning for operations since it is a non-invasive way of ...
As coronary artery disease may also occur during childhood in some specific conditions, we sought to assess the feasibility and accuracy of perfusion cardiovascular magnetic resonance (CMR) in paediatric patients. First-pass perfusion CMR studies were performed under pharmacological stress with adenosine and by using a hybrid echo-planar pulse sequence with slice-selective saturation recovery preparation. Fifty-six perfusion CMR examinations were performed in 47 patients. The median age was 12 years (1 month-18 years), and weight 42.8 kg (2.6-82 kg). General anaesthesia was required in 18 patients. Mean examination time was 67 ± 19 min. Diagnostic image quality was obtained in 54/56 examinations. In 23 cases the acquisition parameters were adapted to patients size. Perfusion CMR was abnormal in 16 examinations. The perfusion defects affected the territory of the left anterior descending coronary artery in 11, of the right coronary artery in 3, and of the circumflex coronary artery in 2 cases. Compared
Position Emission Tomography (PET) - Myocardial Perfusion Scan. PET stands for Positron Emission Tomography and is an imaging technique which uses small amount of a radioactive tracer to help in the diagnosis of heart disease.. The commonest tracer used in Rubidium-82(Rb-82 or 82Rb). 82Rb is a potassium analogue that is a generator product with a physical half-life of 76 seconds. Owing to the distinct advantage of not requiring an on-site cyclotron, 82Rb is the most widely used radioactive tracer for assessment of myocardial perfusion with PET.. The 82Rb tracer is introduced into the body by intravenous (I/V) injection directly from a small portable generator and a PET Scanner is used to produce an image showing the distribution of the tracer in the heart muscles.. Following the intravenous administration, 82Rb is carried in the blood stream and in the blood vessels supplying the heart muscles. 82Rb is then rapidly taken up by the heart muscles. 82Rb activity is noted in the heart within the ...
Fingerprint Dive into the research topics of Impact of appropriate use on the prognostic value of single-photon emission computed tomography myocardial perfusion imaging. Together they form a unique fingerprint. ...
A resting myocardial perfusion scan in a procedure in which nuclear radiology is used to assess blood flow to the heart muscle and determine what areas have decreases blood flow.
Question - I recently had a myocardial perfusion scan and holter monitor - QY. Find the answer to this and other Medical questions on JustAnswer
TY - JOUR. T1 - Perfusion vector-a new method to quantify myocardial perfusion scintigraphy images: a simulation study with validation in patients.. AU - Minarik, David. AU - Senneby, Martin. AU - Wollmer, Per. AU - Mansten, Alva. AU - Sjöstrand, Karl. AU - Edenbrandt, Lars. AU - Trägårdh, Elin. PY - 2015. Y1 - 2015. N2 - The interpretation of myocardial perfusion scintigraphy (MPS) largely relies on visual assessment by the physician of the localization and extent of a perfusion defect. The aim of this study was to introduce the concept of the perfusion vector as a new objective quantitative method for further assisting the visual interpretation and to test the concept using simulated MPS images as well as patients.. AB - The interpretation of myocardial perfusion scintigraphy (MPS) largely relies on visual assessment by the physician of the localization and extent of a perfusion defect. The aim of this study was to introduce the concept of the perfusion vector as a new objective ...
Title:Stress Myocardial Perfusion Imaging in the Emergency Department - New Techniques for Speed and Diagnostic Accuracy. VOLUME: 8 ISSUE: 2. Author(s):Sheri D. Harrison, Mark A. Harrison and W. Lane Duvall. Affiliation:Mount Sinai Medical Center, Box 1030, One Gustave L Levy Place, New York, NY 10029, USA.. Keywords:SPECT myocardial perfusion imaging, chest pain unit, stress-only protocol, CZT SPECT, radiation exposure, RADIATION EXPOSURE, Exercise Treadmill Testing, ETT, MYOCARDIAL PERFUSION. Abstract:Emergency room evaluations of patients presenting with chest pain continue to rise, and these evaluations which often include cardiac imaging, are an increasing area of resource utilization in the current health system. Myocardial perfusion imaging from the emergency department remains a vital component of the diagnosis or exclusion of coronary artery disease as the etiology of chest pain. Recent advances in camera technology, and changes to the imaging protocols have allowed MPI to become a more ...
Myocardial perfusion reserve (hyperemic divided by basal myocardial blood flow) describes vasodilator responsiveness of coronaryresistive vessels. The effect of aging and gender on myocardial perfusion reserve remains controversial. Methods: We studied 56 normal volunteers (21 women, 35 men; aged 50 +/- 20 yr, range 21-86 yr) with O-15-water PET to measure myocardial blood flow during basal and hyperemic stales with intravenous dipyridamole (0.56 mg/kg, n = 46) or adenosine (140 mu g/kg/min, n = 10). For comparative analysis, patients were grouped according to age: ,30 yr (n = 11), 30-49 yr (n = 18), 50-69 yr (n = 15) and greater than or equal to 70 yr (n = 12). Results: Overall, basal flow was 1.00 +/- 0.26 ml/min/g and hyperemic flow was 3.31 +/- 1.38 ml/min/g, resulting in a myocardial perfusion reserve of 3.38 +/- 1.35. There was an increase in basal flow with age (r = 0.45, p , 0.025), although hyperemic flow was only lower in patients greater than or equal to 70 yr, causing a significant ...
TY - JOUR. T1 - Computed tomography stress myocardial perfusion imaging in patients considered for revascularization: a comparison with fractional flow reserve. AU - Ko, Brian. AU - Cameron, James. AU - Meredith, Ian. AU - Leung, Michael. AU - Antonis, Paul. AU - Nasis, Arthur. AU - Crossett, Marcus. AU - Hope, Sarah. AU - Lehman, Sam. AU - Troupis, John. AU - DeFrance, Tony. AU - Seneviratne, Sujith. PY - 2012/1. Y1 - 2012/1. N2 - Aims: Adenosine stress computed tomography myocardial perfusion imaging (CTP) is an emerging non-invasive method for detecting myocardial ischaemia. Its value when compared with fractional flow reserve (FFR), a highly accurate index of ischaemia, is unknown. Our aim was to determine the diagnostic accuracy of CTP and its incremental value when used with computed tomography coronary angiography (CTA) for detecting ischaemia compared with FFR. Methods and results: Forty-two patients (126 vessel territories), who had at least one ,50% angiographic stenosis on invasive ...
These programs provide various means to evaluate statistics and comparisons for series of images that stem from myocardial perfusion imaging. mia-2dmyocard-ica This program is used to run a ICA on a series of myocardial perfusion images to create sythetic references that can be used for motion correction by image registration. If the aim is to run a full motion compensation then it is better to create a segmentation set and use mia-2dmyoica-nonrigid. If the input data is given by means of a segmentation set, then on can also use mia-2dmyocard-icaseries. This program is essentially used to test different options on how to run the ICA forreference image creation.. mia-2dmyocard-icaseries This program is used to run a ICA on a series of myocardial perfusion images given in a segmentation set in order to create sythetic references that can be used for motion correction by image registration. If the aim is to run a full motion compensation then it is better run mia-2dmyoica-nonrigid, since this ...
Both ischemic and non-ischemic heart disease can cause disturbances in the myocardial blood volume (MBV), myocardial perfusion and the myocardial extracellular volume fraction (ECV). Recent studies suggest that native myocardial T1 mapping can detect changes in MBV during adenosine stress without the use of contrast agents. Furthermore, native T2 mapping could also potentially be used to quantify changes in myocardial perfusion and/or MBV. Therefore, the aim of this study was to explore the relative contributions of myocardial perfusion, MBV and ECV to native T1 and native T2 at rest and during adenosine stress in normal physiology. Healthy subjects (n = 41, 26 ± 5 years, 51% females) underwent 1.5 T cardiovascular magnetic resonance (CMR) scanning. Quantitative myocardial perfusion [ml/min/g] and MBV [%] maps were computed from first pass perfusion imaging at adenosine stress (140 microg/kg/min infusion) and rest following an intravenous contrast bolus (0.05 mmol/kg, gadobutrol). Native T1 and T2 maps
PURPOSE: To determine whether the assessment of regional wall thickening (WT) in addition to myocardial perfusion from stress supine acquisitions could compensate for the lack of prone acquisition and the corresponding decrease in the diagnostic performance of SPECT myocardial perfusion imaging (MPI) in patients with known or suspected coronary artery disease (CAD). METHODS: The study group comprised 41 patients (123 vessels) with known or suspected CAD prospectively recruited for systematic prone and supine 201Tl stress SPECT MPI. The diagnostic performance of SPECT MPI was determined for various image sets including nongated supine images (supine NG), nongated combined prone and supine images (prone and supine NG) and gated supine images, allowing WT evaluation from NG images in addition to perfusion (supine NG + WT) using invasive coronary angiography and fractional flow reserve as the gold standards. RESULTS: The rate of false positives was significantly higher among the supine NG images
Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. The investigational drug, regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist, the receptor responsible for coronary vasodilation, and is being studied for potential use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies. This study will compare the safety and efficacy of regadenoson to that of Adenoscan in detecting reversible myocardial perfusion defects ...
Myocardial perfusion is an imaging test. Its also called a nuclear stress test. It is done to show how well blood flows through the heart muscle. It also shows how well the heart muscle is pumping. For example, after a heart attack, it may be done to find areas of damaged heart muscle. This test may be done during rest and while you exercise.
Myocardial perfusion is an imaging test. Its also called a nuclear stress test. It is done to show how well blood flows through the heart muscle. It also shows how well the heart muscle is pumping. For example, after a heart attack, it may be done to find areas of damaged heart muscle. This test may be done during rest and while you exercise.
The present study indicates that detection of early allograft vasculopathy is feasible by serial myocardial perfusion scans. Twenty episodes of vasculopathy were detected by thallium-201 scintigraphy in a prospective follow-up of 76 patients. Of the 20 episodes, 13 were not apparent on coronary angiograms, suggesting that perfusion abnormalities may precede angiographic evidence of the disease. These results differ from previous reports of myocardial perfusion scans that failed to confirm the clinical utility of the procedure (18-23). The perfusion scans in the referred studies were performed late after transplantation, after diffuse and chronic involvement of the coronary arteries had probably occurred; at this time, regional perfusion defects are not likely to be detected due to balanced ischemia in various coronary territories (18,23). In fact, 2 of the 76 patients in our cohort also did not demonstrate perfusion abnormalities despite angiographic evidence of the disease. These 2 patients ...
A myocardial perfusion scan takes images of the blood supply (or what your cardiologist may call perfusion) to the heart muscle using a gamma camera. The blood supply is made visible to the camera by using a small amount of radioactive tracer, which is injected into an arm vein. Occasionally an alternative tracer called thallium is used.. Depending on the exact heart condition in question, the procedure may be performed at rest, with the heart under stress or most commonly both. Myocardial scans give information that is useful in diagnosing and managing conditions such as coronary artery disease, dead tissue resulting from a lack of blood supply and diseases of the heart muscle.. A stress myocardial perfusion scan examines the blood supply to the heart muscle using a gamma camera. The blood supply is made visible to the camera by using a small amount of radioactive tracer, which is injected into an arm vein. The injection is given during stress exercise on a treadmill, then again while resting ...
Prognosis in patients with suspected or known ischemic heart disease and normal myocardial perfusion: Long-term outcome and temporal risk ...
The current study extends the results of a number of previous CMR prognostic studies in stable patients with known or suspected CAD. Jahnke et al5 followed up 302 patients after normal stress CMR perfusion and reported a low event rate comparable to that previously reported with nuclear and echocardiographic techniques.4 Subsequently, Pilz et al6 extended these results in a study of 218 patients with normal CMR, reporting similar results. However, not all studies are concordant on this point.7. Although several studies reported outcomes in patients with normal versus abnormal stress perfusion CMR, with respect to incremental prognostic value, Steel et al7 recently reported the additive prognostic value of DE and stress perfusion data over pre-CMR data and each other. The results of our study are consistent with previous reports indicating that the presence and extent of myocardial delayed enhancement provides incremental prognostic value for adverse events.7,15,-,18. The current study extends ...
زمینه و هدف: بیماری های عروق کرونر موجب مرگ و میر، ناتوانی و تحمیل هزینه های زیادی می شود. ارزش تشخیصی اسکن قلب برای تنگی عروق کرونر متفاوت گزارش شده است. هدف این مطالعه بررسی ارزش تشخیصی اسکن در مقایسه با آنژیوگرافی است. روش بررسی: این مطالعه از نوع مقطعی بوده و جامعه آماری بیماران مراجعه کننده به بخش پزشکی هسته ای بیمارستان قلب ساری بودند. 115 بیمار که نتیجه آنژیوگرافی آن ها معلوم بود انتخاب شدند. داده های مربوط به عوامل خطر بیماری عروق کرونر به وسیله پرسش نامه، جمع آوری گشت. نتایج با استفاده از آزمون t و کای اسکور با SPSS و استفاده از شاخص های حساسیت و ویژگی و ...
TY - JOUR. T1 - Myocardial perfusion reserve. T2 - Assessment with multisection, quantitative, first-pass MR imaging. AU - Wilke, Norbert. AU - Jerosch-Herold, Michael. AU - Wang, Ying. AU - Huang, Yimei. AU - Christensen, Betsy V.. AU - Stillman, Arthur E.. AU - Ugurbil, Kamil. AU - McDonald, Kenneth. AU - Wilson, Robert F.. PY - 1997/8. Y1 - 1997/8. N2 - PURPOSE: To demonstrate the feasibility of determining myocardial blood flow changes and the myocardial perfusion reserve with magnetic resonance (MR) first-pass imaging, to validate the MR results by means of comparison with radiolabeled microsphere flow measurements in an animal model, and to compare the coronary flow reserve with the perfusion reserve at MR imaging in patients with hemodynamically nonsignificant coronary lesions and angina. MATERIALS AND METHODS: Arrhythmia-insensitive, first-pass, multisection, T1- weighted MR imaging with contrast agent enhancement was performed in eight pigs with acute ischemia and in eight adult ...
Myocardial Perfusion Imaging is used to diagnose, and estimate the prognosis of patients with coronary artery disease. Increased attention around the use radiation in medical imaging coupled with new software allows the opportunity to try and reduce the radiation perfusion imaging by half. Software advances allow us to process images that have less radiation counts in the heart without losing the ability to determine the degree of heart disease. Patients underwent a usual dose and low dose stress myocardial perfusion technetium 99m study at the Ottawa Heart Institute. There were no significant differences between the images. The image quality and the parameters used determine significant heart disease were similar. We became an early adopter of the low dose studies and now routinely perform this on our patients. We also followed the first cohort of patients for 12 months to ensure that we saw no problems with doing a low dose test in the long term. Although we did not collect data on all of the ...
Cardiovascular events remain one of the most frequent causes of mortality and morbidity worldwide. The majority of cardiac events occur in individuals without known coronary artery disease (CAD) and in low- to intermediate-risk subjects. Thus, the development of improved preventive strategies may substantially benefit from the identification, among apparently intermediate-risk subjects, of those who have a high probability for developing future cardiac events. Cardiac computed tomography and myocardial perfusion scintigraphy (MPS) by single photon emission computed tomography may play a role in this setting. In fact, absence of coronary calcium in cardiac computed tomography and inducible ischaemia in MPS are associated with a very low rate of major cardiac events in the next 3-5 years. Based on current evidence, the evaluation of coronary calcium in primary prevention subjects should be considered in patients classified as intermediate-risk based on traditional risk factors, since high calcium ...
The effects of peripheral cold exposure on myocardial perfusion and function were studied in 13 patients with scleroderma without clinically evident myocardial disease. Ten patients had at least one transient, cold-induced, myocardial perfusion defect visualized by thallium-201 scintigraphy, and 12 had reversible, cold-induced, segmental left ventricular hypokinesis by two-dimensional echocardiography. The 10 patients with transient perfusion defects all had anatomically corresponding ventricular wall motion abnormalities. No one in either of two control groups (9 normal volunteers and 7 patients with chest pain and normal coronary arteriograms) had cold-induced abnormalities. This study is the first to show the simultaneous occurrence of cold-induced abnormalities in myocardial perfusion and function in patients with scleroderma. The results suggest that cold exposure in such patients may elicit transient reflex coronary vasoconstriction resulting in reversible myocardial ischemia and ...
岡山大学審査学位論文 Heart; 100(13), 1008-1015, 2014 掲載 Author version. The final publication is available at BMJ via http://dx.doi.org/10.1136/heartjnl-2013-305468 © 2014 Kazuhiro Osawa et al., licensee BMJ Publishing Group Ltd & British Cardiovascular ...
We examined MCE to evaluate myocardial perfusion. MCE is somewhat limited when used to evaluate myocardial perfusion quantitatively, although it accurately demonstrates the area at risk ([22-25]). Quantitative evaluation of myocardial perfusion using the contrast echo technique requires use of a contrast agent that distributes bubbles of the same density and size throughout all injections and among different subjects, because the echo intensity significantly depends on bubble size and density. There are several studies presenting indexes from the time-intensity curve that are reproducible and reliable when human albumin is used as the contrast agent, bubbles are produced by a sonication method, the contrast solution has no foamy layer and the injection volume and speed are carefully set ([26-36]). Recent work ([37, 38]) has suggested that the ultrasonic power and the gas surrounding the bubbles are major factors in the disruption of bubbles, although these factors have not yet been well ...
The methods were validated and they have already been taken into use in hospitals all over the world. Coronary artery disease is the most common cause of death in the world, and a major cause of hospitalisation. Myocardial perfusion imaging (MPI), which is used to assess the sufficiency of myocardial blood flow, is an important tool in the diagnostics of coronary artery disease and in determining its severity. The scan is usually performed in two phases involving a stress myocardial perfusion imaging scan and a rest myocardial perfusion imaging scan. The patient is given an injection of a radioactive substance, which gets absorbed in those parts of the heart muscle that have normal blood flow. The scan is performed by using a gamma camera which detects radiation coming from the patient. The quality of images obtained by MPI are dependent on a variety of factors, the most significant ones being image noise, photon attenuation, Compton scattering, collimator-detector response (CDR), and patient ...
The assessment of regional myocardial perfusion using magnetic resonance (MR) imaging during the first-pass of a contrast agent bolus requires tracking of the signal time course for each myocardial segment so that a detailed perfusion map can be derived. To obtain such a map in practice, however, is not trivial because deformation of the shape of the myocardium and respiratory induced motion render a major difficulty in this process. This study describes a practical implementation of a real-time interactive MR echo-planar (EPI) myocardial perfusion imaging system and demonstrates an automated approach for motion and deformation tracking of functional myocardial perfusion images. ...
Lowering the administered dose in SPECT myocardial perfusion imaging (MPI) has become an important clinical problem. In this study we investigate the potential benefit of applying a deep learning (DL) approach for suppressing the elevated imaging noise in low-dose SPECT-MPI studies. We adopt a supervised learning approach to train a neural network by using image pairs obtained from full-dose (target) and low-dose (input) acquisitions of the same patients. In the experiments, we made use of acquisitions from 1,052 subjects and demonstrated the approach for two commonly used reconstruction methods in clinical SPECT-MPI: 1) filtered backprojection (FBP), and 2) ordered-subsets expectation-maximization (OSEM) with corrections for attenuation, scatter and resolution. We evaluated the DL output for the clinical task of perfusion-defect detection at a number of successively reduced dose levels (1/2, 1/4, 1/8, 1/16 of full dose). The results indicate that the proposed DL approach can achieve substantial noise
It is of value to determine the amount of viable myocardial tissue in patients suffering from chronic coronary artery disease and ventricular dysfunction. Having the capability of evaluating both myocardial perfusion and function, simultaneously, myocardial scanning by ECG-Gated is an appropriate method for this purpose. The aim of this study was to compare the results of myocardial perfusion and wall motion before and after Coronary Artery Bypass Grafting (CABG), as well as assessment of the efficiency of these parameters for detection of myocardial viability. Forty patients with positive history of previous myocardial infarction and candidate for CABG underwent ECG-Gated SPECT scanning 1 month before and 2-3 months after surgery. Findings of myocardial perfusion and wall motion, obtained from the two phases of the study, were compared. The results showed that functional status of some preoperatively severely hypoperfused segments, recovered significantly after CABG, which proved existence of viable
Coronary artery calcium scoring has been tested at the University of Western Ontario to flag nuclear myocardial perfusion scans that missed the presence of three-vessel coronary artery disease, and to triage patients who need coronary CT angiography or cardiac catheterization.
TY - JOUR. T1 - Radiation Dose Reduction from Radionuclide Myocardial Perfusion Imaging. AU - Marcassa, Claudio. AU - Zoccarato, Orazio. PY - 2016/1/1. Y1 - 2016/1/1. N2 - Due to a tremendous increase in imaging usage in the last decades, in particular of myocardial perfusion imaging with radionuclide tracers, significant concerns have been recently raised on the possible harmful effect of the exposure of patients and health care operators to ionizing radiation. Recent estimates indicate that cardiac imaging procedures account for almost 40 % of the cumulative dose for imaging procedures. Thus, pertinent scientific associations published recommendations directed to limit patients exposure. The key points in the dose optimization process, including appropriate patients selection, stress test and study protocol, new processing software and new hardware, are described.. AB - Due to a tremendous increase in imaging usage in the last decades, in particular of myocardial perfusion imaging with ...
A Myocardial Perfusion Scan images the blood supply (perfusion) to the heart muscle using a gamma camera. The blood supply is made visible to the camera by the introduction of a small amount of radioactive tracer (radiopharmaceutical or MIBI) injected ...
A myocardial perfusion scan looks at the pumping action of the heart and the flow of blood to the heart to help diagnose coronary heart disease.
Background: Outcomes data are crucial to developing new technology. Coronary computed tomographic angiography (CTA) is rapidly gaining acceptance for assessing coronary artery disease (CAD) extent and severity. This studys aim was to compare prognosis by CTA to a matched cohort undergoing myocardial perfusion SPECT (MPS).. Methods: We prospectively enrolled 1,138 patients (pts.) referred to CTA (16 slice multidetector CT, GE Healthcare) with suspected or progressive CAD (47% intermediate likelihood [LK]), assessed with the Duke CAD index (validated angiographic score subsetting proximal, extensive, and left main CAD). This cohort was matched to 7,849 pts. undergoing MPS from which % ischemic myocardium was defined with a 20-segment model. Death from all-causes was estimated using Cox proportional hazards models adjusting for pretest LK.. Results: For CTA, 39 deaths were observed at 1.5 years of follow-up; a rate similar to MPS (annual mortality: CTA=1.16% vs.MPS=1.13%). The Duke index was ...
The aim of the study was to evaluate the contribution to moscintigraphy of myocardial perfusion (TSMP) with 99mTc-sestamibi in the management of suspected or known coronary patientss population. It included 42 patients with an average age of 57.02 ± 9.77 years with extremes ranging from 36 to 77 years. The pre-test probability in 38 patients was high in 7 patients (18.42%), intermediate in 29 patients (76.31%) and low in 2 patients (5.26%). Patients with a high pre-test probability had a positive scintigraphy. Among the 26 patients who underwent transthoracic ultrasound (TTU), 10 with normal kinetics on trans-thoracic ultrasound (TTU) had positive scintigraphy. For 16 patients with TTU abnormalities, 6 had negative scintigraphy and 10 had positive scintigraphy. The TSMP was positive for 28 patients (66.66%). Among these patients, 16 had pure ischemia, 57.14% (16/28), 7 pure necrosis (25%), and 5 both necrosis and ischemia. Myocardial perfusion scintigraphy remains a very contributory
Myocardial perfusion imaging (MPI) is a commonly used diagnostic modality for risk stratification in patients with known or suspected coronary artery
TY - JOUR. T1 - Accelerated dual-contrast first-pass perfusion MRI of the mouse heart. T2 - Development and application to diet-induced obese mice. AU - Naresh, Nivedita K.. AU - Chen, Xiao. AU - Roy, Rene J.. AU - Antkowiak, Patrick F.. AU - Annex, Brian H.. AU - Epstein, Frederick H.. PY - 2015/3/1. Y1 - 2015/3/1. N2 - Purpose: Gene-modified mice may be used to elucidate molecular mechanisms underlying abnormal myocardial blood flow (MBF). We sought to develop a quantitative myocardial perfusion imaging technique for mice and to test the hypothesis that myocardial perfusion reserve (MPR) is reduced in a mouse model of diet-induced obesity (DIO). Methods: A dual-contrast saturation-recovery sequence with ky-t undersampling and a motion-compensated compressed sensing reconstruction algorithm was developed for first-pass MRI on a small-bore 7 Tesla system. Control mice were imaged at rest and with the vasodilators ATL313 and Regadenoson (n = 6 each). In addition, we imaged mice fed a high-fat ...
TY - JOUR. T1 - Safety of and tolerance to adenosine infusion for myocardial perfusion single-photon emission computed tomography in a Japanese population. AU - Hatanaka, Kunihiko. AU - Doi, Masayuki. AU - Hirohata, Satoshi. AU - Kamikawa, Shigeshi. AU - Kaji, Yoko. AU - Katoh, Tsutomu. AU - Kusachi, Shozo. AU - Ninomiya, Yoshifumi. AU - Ohe, Tohru. PY - 2007. Y1 - 2007. N2 - Background: Adenosine has been available for use in myocardial perfusion single-photon emission computed tomography (SPECT) in Japan since 2005. The purpose of this study was to evaluate the safety of and tolerance to thallium-201 myocardial perfusion SPECT with intravenous adenosine infusion in Japanese patients with suspected coronary artery disease. Methods and Results: Two hundred and six consecutive patients who underwent an adenosine infusion (120•g•·kg-1·min-1) SPECT at Sumitomo Besshi Hospital (Niihama, Japan) were investigated. The effects of adenosine infusion were monitored for each patient. A coronary ...
TY - JOUR. T1 - Quantitative myocardial perfusion PET parametric imaging at the voxel-level. AU - Mohy-Ud-Din, Hassan. AU - Lodge, Martin A.. AU - Rahmim, Arman. N1 - Publisher Copyright: © 2015 Institute of Physics and Engineering in Medicine. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 2015/8/7. Y1 - 2015/8/7. N2 - Quantitative myocardial perfusion (MP) PET has the potential to enhance detection of early stages of atherosclerosis or microvascular dysfunction, characterization of flow-limiting effects of coronary artery disease (CAD), and identification of balanced reduction of flow due to multivessel stenosis. We aim to enable quantitative MP-PET at the individual voxel level, which has the potential to allow enhanced visualization and quantification of myocardial blood flow (MBF) and flow reserve (MFR) as computed from uptake parametric images. This framework is especially challenging for the 82Rb radiotracer. The short half-life enables fast serial imaging and high ...
TY - JOUR. T1 - Prognostic implications of myocardial perfusion single-photon emission computed tomography in the elderly. AU - Hachamovitch, Rory. AU - Kang, Xingping. AU - Amanullah, Aman M.. AU - Abidov, Aiden. AU - Hayes, Sean W.. AU - Friedman, John D.. AU - Cohen, Ishac. AU - Thomson, Louise E.J.. AU - Germano, Guido. AU - Berman, Daniel S.. PY - 2009/12. Y1 - 2009/12. N2 - BACKGROUND- The goal of this study was to assess the clinical value of stress myocardial perfusion scintigraphy (MPS) in elderly patients (,75 years of age). METHODS AND RESULTS: We followed up 5200 elderly patients (41% exercise) after dual-isotope MPS over 2.8±1.7 years (362 cardiac deaths [CDs], 7.0%, 2.6%/y) and a subset with extended follow-up (684 patients for 6.2±2.9 years; 320 all-cause deaths). Survival modeling of CD revealed that both MPS-measured ischemia and fixed defect added incrementally to pre-MPS data in both adenosine and exercise stress patients. Modeling a subset with gated MPS (n=2472) revealed ...
PURPOSE: To assess the diagnostic performance of a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors for nuclear myocardial perfusion imaging (MPI). METHODS: The study group comprised 75 consecutive patients (55 men, BMI range 19-45 kg/m(2)) who underwent a 1-day (99m)Tc-tetrofosmin adenosine-stress/rest imaging protocol. Scanning was performed first on a conventional dual-detector SPECT gamma camera (Ventri, GE Healthcare) with a 15-min acquisition time each for stress and rest. All scans were immediately repeated on an ultrafast CZT camera (Discovery 530 NMc, GE Healthcare) with a 3-min scan time for stress and a 2-min scan time for rest. Clinical agreement (normal, ischaemia, scar) between CZT and SPECT was assessed for each patient and for each coronary territory using SPECT MPI as the reference standard. Segmental myocardial tracer uptake values (percent of maximum) using a 20-segment model and left ventricular ejection fraction (EF) ...
Poster: ESCR 2016 / P-0024 / Quantitative myocardial perfusion measured before and after invasive treatment using advanced CT-technology by: T. Rienmüller1, C. Baumgartner1, V. Makarenko2, V. Bereznitskiy2, I. Rychina2, P. Ourednicek3, R. Rienmüller1; 1Graz/AT, 2Moscow/RU, 3Brno/CZ
TY - JOUR. T1 - Coronary stenosis severity assessed by 256-slice MDCT angiography in comparison with stress myocardial perfusion imaging. AU - Yonezawa, Masato. AU - Higuchi, K.. AU - Yamazaki, Y.. AU - Jinnouchi, M.. AU - Maruoka, Y.. AU - Isoda, T.. AU - Kamitani, T.. AU - Baba, S.. AU - Matsuo, Y.. AU - Abe, K.. AU - Honda, H.. PY - 2012/1/10. Y1 - 2012/1/10. N2 - We evaluated the feasibility of 256-slice MDCT for detecting coronary artery stenosis without beta blocker premedication, and assessed the diagnostic accuracy of MDCT for detecting myocardial ischemia by 201Tl SPECT. Fifty-three patients underwent both coronary CT angiography and stress myocardial perfusion SPECT. All coronary arteries were assessable with appropriate image quality. MDCT revealed high specificity, but only half of stenotic lesion by MDCT revealed ischemia on SPECT.. AB - We evaluated the feasibility of 256-slice MDCT for detecting coronary artery stenosis without beta blocker premedication, and assessed the ...
The Combined Coronary angiography and myocardial perfusion imaging using 320 detectors computed tomography (CORE-320) was designed as a prospective, multi-center, international, blinded study designed to evaluate the diagnostic accuracy of multi-detector computed tomography using 320 detectors for identifying coronary artery luminal stenosis and corresponding myocardium perfusion defects in patients with suspected coronary artery disease. The primary analysis will be a comparison of the diagnostic capability of the combination of quantitative 320-MDCT angiography and quantitative perfusion imaging to the combination of conventional coronary angiography and SPECT myocardial perfusion imaging at the patient level. A positive patient will be defined as having at least one vessel with a ≥ 50% diameter stenosis defined by quantitative coronary angiography and a corresponding positive SPECT territorial myocardial perfusion defect ...
TY - JOUR. T1 - Cardiac contraction motion compensation in gated myocardial perfusion SPECT. T2 - A comparative study. AU - Salehi, Narges. AU - Rahmim, Arman. AU - Fatemizadeh, Emad. AU - Akbarzadeh, Afshin. AU - Farahani, Mohammad Hossein. AU - Farzanefar, Saeed. AU - Ay, Mohammad Reza. PY - 2018/5/1. Y1 - 2018/5/1. N2 - Introduction: Cardiac contraction significantly degrades quality and quantitative accuracy of gated myocardial perfusion SPECT (MPS) images. In this study, we aimed to explore different techniques in motion-compensated temporal processing of MPS images and their impact on image quality and quantitative accuracy. Material and method: 50 patients without known heart condition underwent gated MPS. 3D motion compensation methods using Motion Freezing by Cedars Sinai (MF), Log-domain Diffeomorphic Demons (LDD) and Free-Form Deformation (FFD) were applied to warp all image phases to fit the end-diastolic (ED) phase. Afterwards, myocardial wall thickness, myocardial to blood pool ...
Technetium-labeled agents, which are most often used for assessing myocardial perfusion in myocardial perfusion scintigraphy (MPS), are cleared by the liver and excreted by the biliary system. Spillover from extra-cardiac activity into the myocardium, especially the inferior wall, might conceal defects and lower the diagnostic accuracy of the study. The objective was to determine rules of thumb for when reacquisition is useful due to high extra-cardiac uptake, i.e., when interpretation of the studies was affected by poor image quality. Patients admitted to MPS at any of the three study sites, who also underwent a reacquisition due to high extra-cardiac uptake were included. Image quality was assessed by ten technologists on a scale ranging from 1 to 5. Interpretations regarding the presence/absence of ischemia/infarction, including the certainty of the diagnosis, were made by three physicians. There was a statistically significant increase in image quality between the first and the repeated acquisition
Different software tools for quantification of myocardial perfusion SPECT (MPS) studies are routinely used. Several perfusion parameters can be computed automatically. Interpretation of the MPS should start with visual inspection of the rotating planar images, visual analysis of reconstructed SPECT slices and then quantitative analysis to confirm the visual impression. Quantification should be used routinely as complementary to visual analysis. Advantages of quantification are: greater confidence in interpretation, better reproducibility, diagnostic accuracy and measuring the degree of abnormality even subtle changes for serial comparisons. In this review, we look at the common features of such quantitative tools: 17-segment scoring system, polar maps including: raw, severity and extent polar maps, lung-to-heart ratio, transient ischemic dilation ratio, total perfusion deficit and spherecity index.
AIMS: To evaluate the diagnostic power of integrating the results of computed tomography angiography (CTA) and CT myocardial perfusion (CTP) to identify coronary artery disease (CAD) defined as a flow limiting coronary artery stenosis causing a perfusion defect by single photon emission computed tomography (SPECT). METHODS AND RESULTS: We conducted a multicentre study to evaluate the accuracy of integrated CTA-CTP for the identification of patients with flow-limiting CAD defined by ≥50% stenosis by invasive coronary angiography (ICA) with a corresponding perfusion deficit on stress single photon emission computed tomography (SPECT/MPI). Sixteen centres enroled 381 patients who underwent combined CTA-CTP and SPECT/MPI prior to conventional coronary angiography. All four image modalities were analysed in blinded independent core laboratories. The prevalence of obstructive CAD defined by combined ICA-SPECT/MPI and ICA alone was 38 and 59%, respectively. The patient-based diagnostic accuracy ...
Abstract & Presentation • Reproducibility of 3-D MSPECT for Quantitative Gated SPECT Sestamibi Perfusion Analysis • Journal of Nuclear Medicine • J. N. Kritzman; University of Michigan • Read Abstract • Read Presentation
Background: Myocardial perfusion scintigraphy (MPS) is a well-established diagnostic tool. The sensitivity and specificity of single photon emission computed tomography (SPECT) MPS to detect significant coronary lesion were 86% and 74%, respectively. The aim of this study was to examine the role of serum copeptin in evaluation of MPS.. Methods: Sixty-two consecutive patients underwent both SPECT MPS using 99mTc-sestamibi and transthoracic echocardiography were enrolled prospectively. Age, gender, height, weight, presence of cardiovascular risk factors were recorded. Exercise treadmill test (ETT) with modified Bruce protocol was used to induce coronary ischemia during MPS. While performing MPS, blood samples for serum copeptin level were drawn three times at pre-exercise, at the peak of ETT, and 6 h after ETT, respectively. The patients were enrolled into three groups according to MPS results (normal, equivocal and ischemia).. Results: The study included 62 patients (23 with normal, 20 with ...
Purpose: Shortening scan time and/or reducing radiation dose at maintained image quality are the main issues of the current research in radionuclide myocardial perfusion imaging (MPI). We aimed to validate a new iterative reconstruction (IR) algorithm for SPECT MPI allowing shortened acquisition time (HALF time) while maintaining image quality vs. standard full time acquisition (FULL time). Methods: In this study, 50 patients, referred for evaluation of known or suspected coronary artery disease by SPECT MPI using 99mTc-Tetrofosmin, underwent 1-day adenosine stress 300MBq/rest 900MBq protocol with standard (stress 15min/rest 15min FULL time) immediately followed by short emission scan (stress 9min/rest 7min HALF time) on a Ventri SPECT camera (GE Healthcare). FULL time scans were processed with IR, short scans were additionally processed with a recently developed software algorithm for HALF time emission scans. All reconstructions were subsequently analyzed using commercially available software (QPS/QGS
Abstract. Background: An analysis of the US National Cardiovascular Data Registry has revealed that only 38% of patients referred for coronary angiography after non-invasive coronary testing have relevant coronary obstruction (CO) (≥70%) of one or more coronary arteries.. Methods: A single-center trial was undertaken in 165 consecutive, symptomatic patients with either known or suspected coronary disease and/or valve disease(VHD) who agreed to undergo cardiac catheterization and coronary angiography if stress myocardial perfusion imaging was abnormal. A total of 116 patients with abnormal SPECT MPI tests, persistent chest pain, or significant VHD underwent final analysis. An MCG coronary obstruction (CO) score of ≥ 4.0 was considered indicative of relevant CO (≥70%) in one or more coronary arteries. Angiographic results were finalized by consensus of two angiographers.. Results: CO (≥70%) was present in 53 of 116 patients (46%). The MCG CO score was significantly higher for patients with ...
The evaluation of stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has a leading role in the identification of coronary artery disease, and has excellent diagnostic and prognostic value. Non-invasive MPI can be performed using conventional and novel gamma cameras or by PET/CT. New software has allowed novel parameters that may have a role in the identification of early marks of cardiac impairment to be evaluated. We aim to give an overview of niche parameters obtainable by single photon emission CT (SPECT) and PET/CT MPI that may help practitioners to detect initial signs of cardiac damage and identify new therapy targets. In particular, we summarise the role of left ventricular geometry indices for remodelling, phase analysis parameters to evaluate mechanical dyssynchrony, the concept of relative flow reserve in the evaluation of flow-limiting epicardial stenosis, vascular age and epicardial adipose tissue as early markers of atherosclerotic
TY - JOUR. T1 - Myocardial perfusion abnormalities in asymptomatic patients with systemic lupus erythematosus. AU - Hosenpud, Jeffrey D.. AU - Montanaro, Anthony. AU - Hart, Mark V.. AU - Haines, James E.. AU - Specht, H. David. AU - Bennett, Robert M.. AU - Kloster, Frank E.. PY - 1984/8. Y1 - 1984/8. N2 - Accelerated coronary artery disease and myocardial infarction in young patients with systemic lupus erythematosus is well documented; however, the prevalence of coronary involvement is unknown. Accordingly, 26 patients with systemic lupus were selected irrespective of previous cardiac history to undergo exercise thallium-201 cardiac scintigraphy. Segmental perfusion abnormalities were present in 10 of the 26 studies (38.5 percent). Five patients had reversible defects suggesting ischemia, four patients had persistent defects consistent with scar, and one patient had both reversible and persistent defects in two areas. There was no correlation between positive thallium results and duration of ...
TY - JOUR. T1 - Advances in PET myocardial perfusion imaging. T2 - F-18 labeled tracers. AU - Rischpler, Christoph. AU - Park, Min Jae. AU - Fung, George S.K.. AU - Javadi, Mehrbod. AU - Tsui, Benjamin M.W.. AU - Higuchi, Takahiro. PY - 2012/1/1. Y1 - 2012/1/1. N2 - Coronary artery disease and its related cardiac disorders represent the most common cause of death in the USA and Western world. Despite advancements in treatment and accompanying improvements in outcome with current diagnostic and therapeutic modalities, it is the correct assignment of these diagnostic techniques and treatment options which are crucial. From a diagnostic standpoint, SPECT myocardial perfusion imaging (MPI) using traditional radiotracers like thallium-201 chloride, Tc-99m sestamibi or Tc-99m tetrofosmin is the most utilized imaging technique. However, PET MPI using N-13 ammonia, rubidium-82 chloride or O-15 water is increasing in availability and usage as a result of the growing number of medical centers with ...
Dorbala S, Di Carli MF, Beanlands RS, Merhige ME, Williams BA, Veledar E, Chow BJ, Min JK, Pencina MJ, Berman DS, Shaw LJ. Prognostic value of stress myocardial perfusion positron emission tomography: results from a multicenter observational registry. J Am Coll Cardiol. 2013 Jan 15; 61(2):176-84 ...
Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study ...
Myocardial Perfusion Imaging for Evaluation and Triage of Patients with Suspected Acute Cardiac Ischemia: A Randomized Controlled Trial. - Myocardial Perfusion Imaging for Evaluation and Triage of Patients with Suspected Acute Cardiac Ischemia: A Randomized Controlled Trial ...
A PET Myocardial Perfusion (MP) Stress Test evaluates the blood flow (perfusion) through the coronary arteries to the heart muscle using a radioactive tracer.
article{termeer-2008-vis, title = Visualization of Myocardial Perfusion Derived from Coronary Anatomy, author = Maurice Termeer and Javier Oliv\{a}n Besc\{o}s and Marcel Breeuwer and Anna Vilanova and Frans Gerritsen and Meister Eduard Gr\{o}ller and Eike Nagel, year = 2008, abstract = Visually assessing the effect of the coronary artery anatomy on the perfusion of the heart muscle in patients with coronary artery disease remains a challenging task. We explore the feasibility of visualizing this effect on perfusion using a numerical approach. We perform a computational simulation of the way blood is perfused throughout the myocardium purely based on information from a three-dimensional anatomical tomographic scan. The results are subsequently visualized using both three-dimensional visualizations and bulls eye plots, partially inspired by approaches currently common in medical practice. Our approach results in a comprehensive visualization of the coronary anatomy that compares well to ...
Hachamovitch R, Nutter B, Hlatky MA, Shaw LJ, Ridner ML, Dorbala S, Beanlands RS, Chow BJ, Branscomb E, Chareonthaitawee P, Weigold WG, Voros S, Abbara S, Yasuda T, Jacobs JE, Lesser J, Berman DS, Thomson LE, Raman S, Heller GV, Schussheim A, Brunken R, Williams KA, Farkas S, Delbeke D, Schoepf UJ, Reichek N, Rabinowitz S, Sigman SR, Patterson R, Corn CR, White R, Kazerooni E, Corbett J, Bokhari S, Machac J, Guarneri E, Borges-Neto S, Millstine JW, Caldwell J, Arrighi J, Hoffmann U, Budoff M, Lima J, Johnson JR, Johnson B, Gaber M, Williams JA, Foster C, Hainer J, Di Carli MF. Patient management after noninvasive cardiac imaging results from SPARC (Study of myocardial perfusion and coronary anatomy imaging roles in coronary artery disease). J Am Coll Cardiol. 2012 Jan 31; 59(5):462-74 ...
Perfusion data characterize the regional blood flow in human tissue. In the diagnosis of the Coronary Heart Disease, they are acquired to detect hypoperfused regions of the myocardium (heart muscle) at an early stage or to evaluate the hemodynamical relevance of a known pathologic vessel narrowing. For each voxel in the data, a time-intensity curve describes the enhancement of a contrast agent. Parameters derived from these curves characterize the regional perfusion and have to be integrated for diagnosis. The diagnostic evaluation of this multi-field data is challenging and time-consuming due to its complexity. We tackle this problem by developing a glyph-based integrated visualization of perfusion parameters in 3D-space with the patient-individual ventricular anatomy as context information. Besides the assessment of myocardial perfusion, current cardiac imaging technology allows for the investigation of myocardial contractility as well as for the detection of non-viable tissue. The combined ...
TY - GEN. T1 - Automatic assessment of cardiac perfusion MRI. AU - Ólafsdóttir, Hildur. AU - Stegmann, Mikkel Bille. AU - Larsson, Henrik B.W.. PY - 2004. Y1 - 2004. N2 - In this paper, a method based on Active Appearance Models (AAM) is applied for automatic registration of myocardial perfusion MRI. A semi-quantitative perfusion assessment of the registered image sequences is presented. This includes the formation of perfusion maps for three parameters; maximum up-slope, peak and time-to-peak.. AB - In this paper, a method based on Active Appearance Models (AAM) is applied for automatic registration of myocardial perfusion MRI. A semi-quantitative perfusion assessment of the registered image sequences is presented. This includes the formation of perfusion maps for three parameters; maximum up-slope, peak and time-to-peak.. M3 - Article in proceedings. BT - Medical image computing and computer assisted intervention, MICCAI. PB - Springer. T2 - Medical image computing and computer assisted ...
TY - JOUR. T1 - Perfusion scintigraphy of the heart and lungs in Ayerzas disease (practical case). AU - Vesnina, Zh V.. AU - Babokin, V. E.. AU - Chernov, V. I.. AU - Krivonogov, N. G.. AU - Sokolov, A. A.. AU - Markov, V. V.. AU - Gulyaev, V. M.. AU - Taranov, S. V.. AU - Lishmanov, Yu B.. PY - 2002. Y1 - 2002. N2 - The potential of perfusion scintigraphy is considered on the basic on the practical case. The patient with the preliminary diagnosis as myocardial ischemia was subjected to the 99mTc single-photon emission computerized tomography of myocardium and the 99mTc perfusion scintigraphy of lung. On the basis of obtained results the clinical diagnosis was thrombophlebitis of lower limbs, infarct-pneumonia, lung hypertension. But the pathologico-anatomic diagnosis was Ayerzas disease. The causes of the diagnostic error are discussed.. AB - The potential of perfusion scintigraphy is considered on the basic on the practical case. The patient with the preliminary diagnosis as myocardial ...
Title: Microcirculation Dysfunction: A Possible Mechanism Responsible for Reverse Redistribution in Myocardial Perfusion Imaging?. VOLUME: 5 ISSUE: 4. Author(s):Yong-Ming He and Xiang-Jun Yang. Affiliation:Department of Cardiology, the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu Province, Peoples Republic of China, 215006.. Keywords:Reverse redistribution, single photon emission tomography, coronary artery diseases, mechanism. Abstract: In the past more than one fourth century, the reverse redistribution (RR) phenomenon has been explored extensively and deeply, but its pathogenesis and clinical significances have remained unclear, which has perplexed nuclear specialists and cardiologists in the clinical practice. This paper reviewed the spectrum of the RR phenomenon in different entities and in different radiotracers. A close attention has been paid to the clinical significances, clinical approaching strategies and underlying mechanism of reverse redistribution in coronary ...
Abstract. We hypothesized that among patients presenting with dyspnea on exertion (DOE), those who were found to have hyperdynamic left ventricle (i.e. LVEF ≥ 70%) on stress radionuclide myocardial perfusion imaging (RNMPI), are more likely to have features of diastolic dysfunction on transthoracic echocardiography. Medical records of 1892 consecutive patients who presented between February 2011 and September 2012 with the chief complaint of DOE and were referred to stress RNMPI were reviewed. Among these, patients who had no evidence of reversible ischemia and had hyperdynamic left ventricle on perfusion imaging, were selected and their recent echocardiograms were reviewed for evidence of diastolic dysfunction. Logistic regression analysis was used to develop an equation to predict diastolic dysfunction with the ejection fraction as the predictor. A two-way analysis of variance model was used to detect differential patterns of ejection fraction across diastolic dysfunction and gender. A ...
First pass myocardial perfusion MR imaging with Gd-DOTA : a mean to differentiate occlusive from reperfused acute myocardial ...
OverviewThe Myocardial Perfusion Nuclear Medicine Study demonstrates the distribution of blood flow and perfusion to the mycocardium at stress and rest.
Siemens has developed software (Flash3D) incor- porating iterative fast OSEM reconstruction with 3D resolution recovery, 3D Collimator and Detector Response Correction, and attenuation
TY - JOUR. T1 - Quantification of Individual Sensitivities to Ethanol in Selective Breeding Experiments. T2 - Difference Scores Versus Regression Residuals. AU - Crabbe, John C.. AU - Weigel, Ronald M.. PY - 1987/12. Y1 - 1987/12. N2 - Nagoshi et al. (Alcohol Clin Exp Res 10:343-349, 1986) have argued recently that the use of postdrug minus predrug difference scores to assess individual variability in sensitivity or tolerance to ethanol is not to be recommended. Unreliability of variables can result in biased estimates of response to treatment. Instead of difference scores, they recommend using residual scores from the regression of posttreatment on pretreatment measures. We were interested in the consequences of employing difference scores versus regression residuals for a related, but different purpose: the choice of individual animals to be mated for a selective breeding study. The availability of data from such a selective breeding experiment ongoing in the laboratory of one of us (JCC) ...
AimsWe aimed to investigate the impact of admission estimated glomerular filtration rates (eGFR) on the development of poor myocardial perfusion after primary percutaneous coronary intervention (pPCI) in patients presenting with acute ST-segment-elevation myocardial infarction (STEMI).Materials and
Comparison of Radiation Doses and Best-Practice Use for Myocardial Perfusion Imaging in US and Non-US Laboratories - UltraSPECT |
Myocardial perfusion imaging uses a small amount of radioactive racer to check the blood flow to your heart. Learn more about this treatment at Beaumont.
An isolated blood-perfused pig heart preparation to study myocardial perfusion with blood-pool gadolinium-chelate enhanced ultrafast MRI. High-power gradient MR- ...
Learn more about Myocardial Perfusion Imaging at Medical City Healthcare DefinitionReasons for TestPossible ComplicationsWhat to ExpectCall Your Doctorrevision ...
TY - CHAP. T1 - Cardiac Imaging. AU - Abidov, Aiden. AU - Berman, Daniel S.. PY - 2012/10/3. Y1 - 2012/10/3. KW - CCTA on cardiology and asymptomatic assessment, unclear. KW - CRT in heart failure management, and biventricular pacing. KW - Cardiac imaging. KW - Diagnostic value of myocardial perfusion imaging. KW - Effective therapies, preventing CAD and its consequences. KW - Myocardial perfusion imaging with SPECT or PET. KW - Non-invasive cardiac imaging in clinical management. KW - Non-invasive with echocardiography, MRI, MPI, SPECT/PET. KW - Nuclear cardiology in clinical decision-making, evidence-based. KW - SPECT MPI, risk stratification with CAD extent/severity. UR - http://www.scopus.com/inward/record.url?scp=84886505228&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84886505228&partnerID=8YFLogxK. U2 - 10.1002/9781118399378.ch11. DO - 10.1002/9781118399378.ch11. M3 - Chapter. AN - SCOPUS:84886505228. SN - 9781405162159. SP - 296. EP - 344. BT - Cardiovascular ...
article{Fricke_Elsner_Weise_Bolte_van den Hoff_Burchert_Domik_Fricke_2009, title={Quantitative myocardial perfusion PET combined with coronary anatomy derived from CT angiography: Validation of a new fusion and visualisation software}, volume={19}, number={3}, journal={Zeitschrift f{\u}r Medizinische Physik}, publisher={Elsevier}, author={Fricke, Harald and Elsner, Andreas and Weise, Reiner and Bolte, Matthias and van den Hoff, J{\ and Burchert, Wolfgang and Domik, Gitta and Fricke, Eva}, year={2009}, pages={182-188 ...
Conventional ultrasound (US) provides important qualitative information, although there is a need to evaluate the influence of the input parameters on the output signal and standardise the acquisition for an adequate quantitative perfusion assessment. The present study analyses how the variation in the input parameters influences the measurement of the perfusion parameters. A software tool with simulator of the conventional US signal was created, and the influence of the different input variables on the derived biomarkers was analysed by varying the image acquisition configuration. The input parameters considered were the dynamic range, gain, and frequency of the transducer. Their influence on mean transit time (MTT), the area under the curve (AUC), maximum intensity (MI), and time to peak (TTP) parameters as outputs of the quantitative perfusion analysis was evaluated. A group of 13 patients with hepatocarcinoma was analysed with both a commercial tool and an in-house developed software. The optimal
PURPOSE: To demonstrate the feasibility of imaging the first passage of a bolus of hyperpolarized (13)C urea through the rodent heart using flow-sensitizing gradients to reduce signal from the blood pool. METHODS: A flow-sensitizing bipolar gradient was optimized to reduce the bright signal within the cardiac chambers, enabling improved contrast of the agent within the tissue capillary bed. The gradient was incorporated into a dynamic golden angle spiral (13)C imaging sequence. Healthy rats were scanned during rest (n = 3) and under adenosine stress-induced hyperemia (n = 3). RESULTS: A two-fold increase in myocardial perfusion relative to rest was detected during adenosine stress-induced hyperemia, consistent with a myocardial perfusion reserve of two in rodents. CONCLUSION: The new pulse sequence was used to obtain dynamic images of the first passage of hyperpolarized (13)C urea in the rodent heart, without contamination from bright signal within the neighboring cardiac lumen. This probe of myocardial
PURPOSE: To demonstrate the feasibility of imaging the first passage of a bolus of hyperpolarized (13)C urea through the rodent heart using flow-sensitizing gradients to reduce signal from the blood pool. METHODS: A flow-sensitizing bipolar gradient was optimized to reduce the bright signal within the cardiac chambers, enabling improved contrast of the agent within the tissue capillary bed. The gradient was incorporated into a dynamic golden angle spiral (13)C imaging sequence. Healthy rats were scanned during rest (n = 3) and under adenosine stress-induced hyperemia (n = 3). RESULTS: A two-fold increase in myocardial perfusion relative to rest was detected during adenosine stress-induced hyperemia, consistent with a myocardial perfusion reserve of two in rodents. CONCLUSION: The new pulse sequence was used to obtain dynamic images of the first passage of hyperpolarized (13)C urea in the rodent heart, without contamination from bright signal within the neighboring cardiac lumen. This probe of myocardial
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Computed tomography laser mammography (CTLM) is the trademark of Imaging Diagnostic Systems, Inc. (IDSI, United States) for its ... This medical imaging technique uses laser energy in the near infrared region of the spectrum, to detect angiogenesis in the ... CTLM images show hemoglobin distribution in a tissue and can detect areas of Angiogenesis surrounding malignant tumors, that ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... The image produced by this type of medical imaging, called a cholescintigram, is also known by other names depending on which ... L. Santiago Medina; C. Craig Blackmore; Kimberly Applegate (29 April 2011). Evidence-Based Imaging: Improving the Quality of ... Cholescintigraphic scans are not generally a first-line form of imaging owing to their increased cost and invasiveness.[3] ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... A retrograde urethrogram is a routine radiologic procedure (most typically in males) used to image the integrity of the urethra ... Medical imaging (ICD-9-CM V3 87-88, ICD-10-PCS B, CPT 70010-79999) ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... magnetic resonance imaging, ultrasound imaging, endoscopy and capsule endoscopy,[7] barium contrast imaging remains in common ... providing better imaging conditions and in this case the procedure is called double-contrast imaging.[9] ... Types of barium-contrast imaging[edit]. Barium meal examination showing the stomach and duodenum in double contrast technique ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... In general, fMRI studies acquire both many functional images with fMRI and a structural image with MRI. The structural image is ... This could be either those sections of the image that repeat often in a spatial map (that is small clusters dotting the image ... This spiral imaging sequence acquires images faster than gradient-echo sequences, but needs more math transformations (and ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... images in a similar process to the capture of x-ray images. In contrast, SPECT and positron emission tomography (PET) form 3- ... Certain tests, such as the Schilling test and urea breath test, use radioisotopes but are not used to produce a specific image ... In the ventilation phase of a ventilation/perfusion scan, a gaseous radionuclide xenon or technetium DTPA in an aerosol form ( ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Other imaging technologies such as quantitative computed tomography (QCT) are capable of measuring the bone's volume, and are, ... DXA is not regulated like other radiation-based imaging techniques because of its low dosage. Each US state has a different ... Medical imaging (ICD-9-CM V3 87-88, ICD-10-PCS B, CPT 70010-79999) ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... That is, we wish to find the image μ. (. x. ,. y. ). {\displaystyle \mu (x,y)}. . The simplest and easiest way to visualise the ... Resulting tomographic image from a plastic skull phantom. Projected X-rays are clearly visible on this slice taken with a CT- ... "Principles of Computerized Tomographic Imaging". Slaney.org. Retrieved 7 September 2018.. *Insight ToolKit; open source ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Further imaging depends on local protocols which is dependent on the hospital protocols, the availability of other imaging ... Using Digital Chest Images to Monitor the Health of Coal Miners and Other Workers Archived 2019-01-28 at the Wayback Machine. ... Like all methods of radiography, chest radiography employs ionizing radiation in the form of X-rays to generate images of the ...
... can be used to image blood perfusion in organs, measure blood flow rate in the heart and other ... When used in conjunction with Doppler ultrasound, microbubbles can measure myocardial flow rate to diagnose valve problems. And ... Ultrasonic molecular imaging is safer than molecular imaging modalities such as radionuclide imaging because it does not ... Beside its use to assess cardiac function and perfusion it is also used as an enhancer of the images of prostate, liver, kidney ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... "Cancer Imaging. International Cancer Imaging Society. 5 (Spec No A): S133-S139. doi:10.1102/1470-7330.2005.0108. PMC 1665314. ... After the examination, the images produced by the scanner must be processed into a 3D image, +/- a fly through (a cine program ... Virtual colonoscopy (VC, also called CT Colonography or CT Pneumocolon) is a medical imaging procedure which uses x-rays and ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Medical imaging (ICD-9-CM V3 87-88, ICD-10-PCS B, CPT 70010-79999) ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... "B-mode" imaging, which displays a 2-dimensional image of the skull, brain, and blood vessels as seen by the ultrasound probe. ... Medical imaging (ICD-9-CM V3 87-88, ICD-10-PCS B, CPT 70010-79999) ... Similar to other neuroimaging techniques such as functional magnetic resonance imaging (fMRI) and positron emission tomography ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Other imaging technologies such as quantitative computed tomography (QCT) are capable of measuring the bone's volume, and are, ... DXA is not regulated like other radiation-based imaging techniques because of its low dosage. Each US state has a different ... using spectral imaging. Two X-ray beams, with different energy levels, are aimed at the patient's bones. When soft tissue ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... With digital imaging, however, density may be referred to as brightness. The brightness of the radiograph in digital imaging is ... The image acquisition is generally performed by radiographers, and the images are often examined by radiologists. Plain ... Images having a short-scale of contrast will have narrow exposure latitude. Images having long-scale contrast will have a wide ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Dark image. *Image geometry: of which it compiles of the X-ray beam, object and image receptor all of which depend on a ... The image receptor is placed in a holder and positioned parallel to the long axis of the tooth being imaged. The X-ray tube ... To maintain a high standard of Grade 1 and 2 images each film needs to be examined to put the image into a specific category. ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... X-ray image intensifiers[edit]. Main article: X-ray image intensifier. The invention of X-ray image intensifiers in the 1950s ... Fluoroscopy (/flʊəˈrɒskəpi/[1]) is an imaging technique that uses X-rays to obtain real-time moving images of the interior of ... Imaging concerns[edit]. In addition to spatial blurring factors that plague all X-ray imaging devices, caused by such things as ...
Chemistry portal Myocardial perfusion imaging Dong, Z.-C.; Corbett, J. D. (1996). "Na23K9Tl15.3: An Unusual Zintl Compound ... and Risk Stratification of Coronary Artery Disease by Thallium-201 Myocardial Perfusion Scintigraphy 155". Cardiac SPECT ... Jain, Diwakar; Zaret, Barry L. (2005). "Nuclear imaging in cardiovascular medicine". In Clive Rosendorff (ed.). Essential ... it has good imaging characteristics without excessive patient radiation dose. It is the most popular isotope used for thallium ...
82Rb is widely used in myocardial perfusion imaging. This isotope undergoes rapid uptake by myocardiocytes, which makes it a ... "Story of rubidium-82 and advantages for myocardial perfusion PET imaging". Frontiers in Medicine. 2: 65. doi:10.3389/fmed. ... "Diagnostic Accuracy of Rubidium-82 Myocardial Perfusion Imaging With Hybrid Positron Emission Tomography/Computed Tomography in ... "Generator-produced rubidium-82 positron emission tomography myocardial perfusion imaging-From basic aspects to clinical ...
... images shows the heart as it contracts over the interval from one R wave to the next. Gated myocardial perfusion imaging has ... Gated SPECT is a nuclear medicine imaging technique, typically for the heart in myocardial perfusion imagery. An ... Kuikka, Jyrki T (2007). "Myocardial Perfusion Imaging with Combined Single-photon Emission Computed Tomography and Multislice ... DePasquale, Eugene (25 February 2003). "Role of Myocardial Perfusion Imaging in Managing CAD". Medscape. Retrieved 28 September ...
... such as functional cardiac or brain imaging. Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used ... ISBN 978-1-85233-617-2.. Elhendy et al., Dobutamine Stress Myocardial Perfusion Imaging in Coronary Artery Disease, J Nucl Med ... Elhendy, A; Bax, JJ; Poldermans, D (2002). "Dobutamine stress myocardial perfusion imaging in coronary artery disease". Journal ... gated myocardial SPECT can be used to obtain quantitative information about myocardial perfusion, thickness, and contractility ...
It can be used, amongst other applications, in water for PET myocardial perfusion imaging and for brain imaging. It has 8 ... "Current and Future Status of PET Myocardial Perfusion Tracers". Current Cardiovascular Imaging Reports. 8 (1): 333-343. doi: ... Oxygen-15 is a radioactive isotope of oxygen, frequently used in positron emission tomography (PET) imaging. ...
Williams, M.C.; Newby, D.E. (2016-08-01). "CT myocardial perfusion imaging: current status and future directions". Clinical ... This may also be used on the brain, where CT perfusion imaging can often detect poor brain perfusion well before it is detected ... CT perfusion imaging is a specific form of CT to assess flow through blood vessels whilst injecting a contrast agent. Blood ... These cross-sectional images are made up of small units of pixels or voxels. Pixels in an image obtained by CT scanning are ...
One of the main uses is myocardial perfusion imaging. As a result of changes in the blood-brain barrier in brain tumors, ... allowing the use of radioisotope rubidium-82 in nuclear medicine to locate and image brain tumors. Rubidium-82 has a very short ...
doi:10.1016/S0735-1097(02)80780-X. Anand, D. V; Lahiri, A (2003). "Myocardial perfusion imaging versus biochemical markers in ... Sabharwal, N K (2003). "Role of myocardial perfusion imaging for risk stratification in suspected or known coronary artery ... He also developed TC-99m tetrofosmin (Myoview) for myocardial perfusion imaging in man in conjunction with Amersham ... Contributed in early diagnostic imaging in asymptomatic diabetes. Referenced in the guidelines of imaging in diabetes- American ...
Myocardial perfusion imaging can be abnormal in 30% of patients. Coronary angiogram: Normal Other causes of chest pain must be ... Angiograms may be useful and conclusive when microvascular angina they offer a detailed image of the heart. However, they ... shown to improve angina and myocardial ischemia Statins Aspirin Clopidogrel ACE inhibitors and ARBs Lifestyle changes such as ...
The best known example of a nuclear stress test is myocardial perfusion imaging. Typically, a radiotracer (Tc-99 sestamibi, ... "The role of radionuclide myocardial perfusion imaging for asymptomatic individuals". Journal of Nuclear Cardiology. 18 (1): 3- ... echocardiogram images are obtained. The two echocardiogram images are then compared to assess for any abnormalities in wall ... The images obtained are similar to the ones obtained during a full surface echocardiogram, commonly referred to as ...
February 1993). "Technetium-99m-tetrofosmin as a new radiopharmaceutical for myocardial perfusion imaging". Journal of Nuclear ... December 2005). "Risk stratification of patients with angina pectoris by stress 99mTc-tetrofosmin myocardial perfusion imaging ... Imaging normally begins 15 minutes following injection. Kelly JD, Forster AM, Higley B, Archer CM, Booker FS, Canning LR, et al ... Patients should be encouraged to void their bladders as soon as the images are gathered, and as often as possible after the ...
... is used to tag ammonia molecules for PET myocardial perfusion imaging. 1H + 16O → 13N + 4He The proton must be ...
It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging. It is rapidly ... "Manufacture of strontium-82/rubidium-82 generators and quality control of rubidium-82 chloride for myocardial perfusion imaging ... "Noninvasive assessment of coronary stenoses by myocardial perfusion imaging during pharmacologic coronary vasodilation. VIII. ... can be used to identify regions of heart muscle that are receiving poor blood flow in a technique called PET perfusion imaging ...
... which is created in a portable generator and is used for myocardial perfusion studies. Nevertheless, in recent years a few on- ... Small animal imagingEdit. PET technology for small animal imaging: A miniature PE tomograph has been constructed that is small ... PET imaging is best performed using a dedicated PET scanner. It is also possible to acquire PET images using a conventional ... Musculo-skeletal imagingEdit. Musculoskeletal imaging: PET has been shown to be a feasible technique for studying skeletal ...
The most common severe adverse reactions were pulmonary edema/deep vein thrombosis, splenic rupture, and myocardial infarction ...
Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography. *PET-CT ... Image quality[edit]. Image quality will depend on resolution and density. Resolution is the ability an image to show closely ... It is not used for bone imaging, as the image quality is not good enough to make an accurate diagnostic image for fractures, ... Other medical imaging[edit]. Although not technically radiographic techniques due to not using X-rays, imaging modalities such ...
Unstable cardiovascular status (angina, recent myocardial infarction, etc.). *Thoracic, abdominal, or cerebral aneurysms ... Perfusion (Q) *Ventilation/perfusion ratio. *V/Q scan. *zones of the lung ... Medical imaging. *Bronchography. *CT pulmonary angiogram. *High-resolution computed tomography. *Spiral CT ...
Image North African ostrich (S. c. camelus), also called the red-necked ostrich or Barbary ostrich. Lives in North Africa. ... Upon view, the myocardial cells are observed to have large densely packed chromosomes within the nucleus.[69] ... Finally, they suggest that warm venous blood perfusion at the ophthalmic rete facilitates warming of cerebral blood that ... Image Somali ostrich (S. molybdophanes), also called the blue-necked ostrich. Found in southern Ethiopia, northeastern Kenya, ...
gamma ray: Myocardial perfusion imaging(英语:Myocardial perfusion imaging). PET(正電子):. *Brain PET(英语:Brain positron emission ... Whole body imaging(英语:Whole body imaging) *Full-body CT scan(英语:Full-body CT scan) ... 心血管磁共振成像/Cardiac MRI perfusion(英语:Cardiac MRI perfusion) ... 光学(英语:Optical imaging)激光. *Optical tomography(英语:Optical
Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. Myocardial perfusion imaging. Cardiovascular MRI. ...
gamma ray: Myocardial perfusion imaging. PET (positron):. *Brain PET. *Cardiac PET. *PET mammography ... allowing faster image acquisition: four images per second with 512 lines each. Hugely magnified intermediate images, due to a 1 ... The Development of a Modern Microscopy". Imaging & Microscopy.. online. *^ a b c Barry R. Masters: Confocal Microscopy And ... C.J.R. Sheppard, A. Choudhury: Image Formation in the Scanning Microscope. In: Optica Acta: International Journal of Optics. 24 ...
Main article: Myocardial perfusion imaging. Myocardial perfusion imaging (MPI) is a form of functional cardiac imaging, used ... Myocardial perfusion imagingEdit. This section needs additional citations for verification. Please help improve this article by ... Elhendy et al., Dobutamine Stress Myocardial Perfusion Imaging in Coronary Artery Disease, J Nucl Med 2002 43: 1634-1646 ... "Dobutamine stress myocardial perfusion imaging in coronary artery disease". Journal of Nuclear Medicine. 43 (12): 1634-46. PMID ...
... and Risk Stratification of Coronary Artery Disease by Thallium-201 Myocardial Perfusion Scintigraphy 155. Cardiac SPECT imaging ... Jain, Diwakar; Zaret, Barry L. Nuclear imaging in cardiovascular medicine. (编) Clive Rosendorff. Essential cardiology: ...
The mass of the left ventricle, as estimated by magnetic resonance imaging, averages 143 g ± 38.4 g, with a range of 87 -224 g. ... However, both endocardial and midwall fractional shortening are dependent on myocardial wall thickness, and thereby dependent ... which is independent of myocardial wall thickness". American Journal of Physiology. Heart and Circulatory Physiology. 298 (2): ... is independent of myocardial wall thickness and represents isolated short-axis function.[21] ...
Color Doppler images are generally combined with grayscale (B-mode) images to display duplex ultrasonography images. Uses ... Finally, applications in quantitative perfusion[34] (relative measurement of blood flow[35]) emerge for identifying early ... in echocardiography to improve delineation of left ventricle for visually checking contractibility of heart after a myocardial ... This article is about using ultrasound to image the human body. For imaging of animals in research, see Preclinical imaging. ...
... decreased blood perfusion), myocardial injury,[5] arrhythmias[6] (irregular heartbeats), and improve heart failure by ... a b c Shen, X, Yang, Y, Xiao, T, Peng, J, Liu, X. (2011) Protective effect of oxymatrine on myocardial fibrosis induced by ... Oxymatrine protects against myocardial injury via inhibition of JAK2/STAT3 signaling in rat septic shock. Mol Mod Rep 7(4): ... Cardioprotective effects and underlying mechanisms of oxymatrine against Ischemic myocardial injuries of rats. Phytotherapy ...
Medical imaging[edit]. Radiologic imaging has long been a criterion for diagnosis of ARDS. Original definitions of ARDS ... Physiologic dead space cannot change as it is ventilation without perfusion. A shunt is perfusion without ventilation. ... Cardiac: abnormal heart rhythms, myocardial dysfunction. *Kidney: acute kidney failure, positive fluid balance ... increased organ and tissue perfusion and potential for increased urine output secondary to increased kidney perfusion. ...
"3D fusion of LV venous anatomy on fluoroscopy venograms with epicardial surface on SPECT myocardial perfusion images for ... "IEEE Transactions on Medical Imaging. 36 (11): 2366-2375. doi:10.1109/TMI.2017.2720158. ISSN 0278-0062. PMID 28678701.. ... A venipuncture is made, and a guide wire inserted into the vein, where it is guided, with use of real time X-ray imaging, ... Myocardial perforation, pneumothorax and infection, all of which have an incidence of less than 1% ...
... leading to increased tissue perfusion. This causes the myocardium to work more efficiently, with optimized hemodynamics and an ... It exerts a mechanical effect as it increases myocardial contractility; however, the duration of the contractile response is ... Interactive image. Melting point. 249.3 °C (480.7 °F). Solubility in water. 0.0648 mg/mL (20 °C). ...
Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. Myocardial perfusion imaging. Cardiovascular MRI. ... myocardial infarction; unanticipated reactions to the medications used during the procedure; damage to the conduction system, ...
... can be used to image blood perfusion in organs, measure blood flow rate in the heart and other ... When used in conjunction with Doppler ultrasound, microbubbles can measure myocardial flow rate to diagnose valve problems. And ... Ultrasonic molecular imaging is safer than molecular imaging modalities such as radionuclide imaging because it does not ... Beside its use to assess cardiac function and perfusion it is also used as an enhancer of the images of prostate, liver, kidney ...
Clin Physiol Funct Imaging. 23 (3): 166-70. doi:10.1046/j.1475-097X.2003.00491.x. PMID 12752560.. ... "Influence of heart rate on mortality after acute myocardial infarction". The American Journal of Cardiology. 65 (9): 547-53. ... The mortality rate of patients with myocardial infarction increased from 15% to 41% if their admission heart rate was greater ...
These changes further result in myocardial cell damage in the lining of the heart, leading to scar tissue and thickened walls. ... Enhanced cerebral perfusion may not only facilitate the delivery of energy substrates, but also lower the risk of vascular- ... or myocardial thickness (strength training). Ventricular hypertrophy, the thickening of the ventricular walls, is generally ... Persons who modify their behavior after myocardial infarction to include regular exercise have improved rates of survival. ...
... which is created in a portable generator and is used for myocardial perfusion studies. Nevertheless, in recent years a few on- ... Small animal imaging[edit]. PET technology for small animal imaging: A miniature PE tomograph has been constructed that is ... Musculo-skeletal imaging[edit]. Musculoskeletal imaging: PET has been shown to be a feasible technique for studying skeletal ... 2003). "11C-metomidate PET imaging of adrenocortical cancer". European Journal of Nuclear Medicine and Molecular Imaging. 30 (3 ...
Cardiac imaging. Angiocardiography. Echocardiography TTE. TEE. Myocardial perfusion imaging. Cardiovascular MRI. ... First U.S. Human-to-Human Heart Transplant at Wayne State University Library contains high-definition images from this ...
Myocardial perfusion imaging. Myocardial perfusion imaging, medical procedure that uses radioactive tracers, primarily thallium ... Myocardial perfusion imaging is used to diagnose myocardial ischemia, which is caused by a reduced supply of blood to the heart ... "Myocardial perfusion imaging". Encyclopædia Britannica. Encyclopædia Britannica Online.. Encyclopædia Britannica Inc., 2018. ... Evidence of recent and not-so-recent myocardial infarcts will be visible, but most persons with coronary heart disease who have ...
Myocardial Perfusion Imaging. Hall C. Wednesday: 13:30 15:30. 1558. Assessment of First-Pass Stress and Rest Myocardial ... How Good is Qualitative Analysis of 1st Pass Gd-DTPA Multislice Myocardial Perfusion Imaging for Clinical Evaluation? D.C. ... High Resolution T2-Weighted First-Pass Myocardial Perfusion Imaging Using Outer-Volume Suppression and the Intravascular ... Clinical Application of Myocardial Perfusion Post PTCA with SE-EPI, F.B. Gao, Y.G. Gao, B.S. Qiu, Y. Liang, Y.Q. Cai and X.Y. ...
From 1993 to 2001, myocardial perfusion scans in the US increased >6%/y with "no justification". Myocardial perfusion imaging ... "Resurrection of Thallium-201 for Myocardial Perfusion Imaging". JACC: Cardiovascular Imaging. 2 (3): 283-285. doi:10.1016/j. ... Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the ... Myocardial+Perfusion+Imaging at the US National Library of Medicine Medical Subject Headings (MeSH) Lee, J. C.; West, M. J.; ...
Because myocardial perfusion imaging increases the diagnostic accuracy of stress testing, the American College of Cardiology ... In addition, myocardial perfusion imaging should always be used as an adjunct when pharmacologic stress testing is performed. ... Because myocardial perfusion imaging increases the diagnostic accuracy of stress testing, the American College of Cardiology ... A difficulty that commonly arises is when there is disagreement between the ECG evidence and myocardial perfusion imaging on a ...
Optimizing gated myocardial perfusion imaging processing for phase analysis. J Nucl Cardiol. 2016;23:1348-54.CrossRefPubMed ... Lin X, Xu H, Zhao X, Chen J. Sites of latest mechanical activation as assessed by SPECT myocardial perfusion imaging in ... Left ventricular systolic and diastolic dyssynchrony assessed by phase analysis of gated SPECT myocardial perfusion imaging: a ... Long-term prognostic value of left ventricular dyssynchrony assessment by phase analysis from myocardial perfusion imaging. ...
I had the pleasure to chair the session entitled "Myocardial Perfusion Imaging: State of The Heart". The session was a pleasant ... Furthermore, combining PET perfusion images and the morphologic images of coronary arteries by CT-PET, a comprehensive ... increase the quality of images with the aim of a better definition of endocardial borders or to evaluate myocardial perfusion. ... He also addressed the unique possibility of CMR in evaluating myocardial perfusion without the use of contrast agent based on ...
Exercise CT myocardial perfusion imaging is feasible and accurate for assessment of the functional significance of coronary ... Diagnosis of functionally significant coronary stenosis with exercise CT myocardial perfusion imaging.. Habis M1, Ghostine S, ... CT myocardial perfusion imaging was performed within 1 minute after patients performed supine exercise on an ergometer secured ... The myocardial enhancement ratio between stenotic and normally perfused territories was determined for each stenosis. ...
Phase analysis of gated myocardial perfusion single-photon emission computed tomography compared with tissue doppler imaging ... Prognostic value of left ventricular dyssynchrony evaluated by gated myocardial perfusion imaging in patients with chronic ... Assessment of dyssynchrony by gated myocardial perfusion imaging does not improve patient management. ... Rosen B, Lardo A, Berger D. Imaging of myocardial dyssynchrony in congestive heart failure. Heart Fail Rev. 2006;11:289-303. ...
Myocardial PerfusionMyocardial Perfusion Imaging (MPI) is a diagnostic procedure used to show how well your heart muscle is ... Myocardial Perfusion Imaging. Please note: reference image is displayed in place of Flash media. ... Thallium Stress TestThallium Stress Test is a type of nuclear scanning test or myocardial perfusion imaging test. Myocardial ... Thallium Stress TestThallium Stress Test is a type of nuclear scanning test or myocardial perfusion imaging test. Myocardial ...
Recent research has identified the assessment of myocardial perfusion and viability as another promising CT application for the ... CT Imaging of Myocardial Perfusion and Viability. Book Subtitle. Beyond Structure and Function. Editors. * U. Joseph Schoepf ... CT Imaging of Myocardial Perfusion and Viability. Beyond Structure and Function. Editors: Schoepf, U.J., Bamberg, F., Ruzsics, ... Dynamic, Time-Resolved Imaging of Myocardial Perfusion Using 256-Slice Computed Tomography ...
Dynamic Myocardial Perfusion Imaging by 320 Multidetector Computed Tomography. This study has been completed. ... coronary angiography and imaging of myocardial perfusion, function and viability. ... Myocardial perfusion defects defined qualitatively by trained observers and quantitatively by computer software [ Time Frame: 1 ... tomography can identify myocardial perfusion defects as compared to the gold standards of 3Tesla magnetic resonance imaging and ...
Learn more about Myocardial Perfusion Imaging at Mount Sinai Heart. Get a thorough evaluation of blood flow throughout your ... Myocardial perfusion imaging is a non-invasive imaging testing modality that shows how well the blood flows through (perfuses) ... The imaging tests can show this decrease in blood flow.. Myocardial perfusion studies can identify areas of your heart muscle ... We combine myocardial perfusion images with exercise (walking on a treadmill) to assess the blood flow to the heart muscle. We ...
Myocardial perfusion imaging (MPI) is the most commonly used non-invasive stress imaging test for the diagnosis and risk ... Prognostic Significance of Non-Perfusion Variables Obtained from Exercise and Vasodilator Stress Myocardial Perfusion Imaging. ... Myocardial Perfusion Imaging (MPI): Performance, Potential Risks and Outcomes. Fadi Gabriel Hage, M.D. (Editor). Division of ... Home / Shop / Books / Medicine and Health / Myocardial Perfusion Imaging (MPI): Performance, Potential Risks and Outcomes. ...
Abstract 17187: Clinical Indications, Appropriateness, and Results of Repeat Myocardial Perfusion Imaging. Shepard D Weiner, ... Background: There has been a significant increase in myocardial perfusion imaging (MPI) exams performed. Appropriate use ... Abstract 17187: Clinical Indications, Appropriateness, and Results of Repeat Myocardial Perfusion Imaging ... Abstract 17187: Clinical Indications, Appropriateness, and Results of Repeat Myocardial Perfusion Imaging ...
... myocardial perfusion agents have been under investigation to determine their utility in assessing regional myocardial blood ... In recent years, several technetium 99m-labeled myocardial perfusion agents have been under investigation to determine their ... Coronary Disease / metabolism, radionuclide imaging. Heart / radionuclide imaging*. Humans. Myocardium / metabolism*. Nitriles ... reflects the degree of myocardial salvage and viability. 99mTc teboroxime, another promising new perfusion agent, is a boronic ...
On single-photon emission CT myocardial perfusion (SPECT) wall motion images, the left ventricular chamber was noted to have a ...
Contrast-dose relation in first-pass myocardial MR perfusion imaging View in MDC Repository ... imaging to improve accuracy in myocardial perfusion quantification. Materials and Methods: A total of 10 healthy subjects were ... two series of rest perfusion scans were performed using two different multislice saturation-recovery perfusion sequences. ... Conclusion: Quantitative evaluation of cardiac MR perfusion data needs to account for signal saturation in both the LV blood ...
... is usually performed in two phases involving a stress myocardial perfusion imaging scan and a rest myocardial perfusion imaging ... Myocardial perfusion imaging (MPI), which is used to assess the sufficiency of myocardial blood flow, is an important tool in ... The quality of images obtained by MPI are dependent on a variety of factors, the most significant ones being image noise, ... The study focused on the testing of methods which seek to reduce the imaging time and to correct image problems caused by a ...
Int J Cardiovasc Imaging. 2014 Apr;30(4):803-12. doi: 10.1007/s10554-014-0390-3. Epub 2014 Feb 26. Research Support, Non-U.S. ... Feasibility of dynamic CT-based adenosine stress myocardial perfusion imaging to detect and differentiate ischemic and ... Dynamic CT-perfusion imaging (100 kV, 300 mAs), fluorescent microspheres, and histopathology were performed in all models. CT ... 88.2 ± 22 ml/100 ml/min, p = 0.002). In a large animal model, CT-derived parameters of myocardial perfusion may enable ...
... first-pass myocardial perfusion imaging. Twenty one consecutive first-pass adenosine stress perfusion MR data sets interpreted ... Image artifacts introduced by filtering in registered and nonregistered images were evaluated by two observers. There was a ... KLT only-artifacts in 42 out of 55 image series vs. registered plus KLT-artifacts in 3 out of 55 image series). In conclusion ... the combination of non-rigid registration and KLT filtering was shown to increase the SNR and CNR of GRE-EPI perfusion images. ...
... a study by G-SPECT myocardial perfusion imaging Eur J Nucl Med Mol Imaging. 2010 Dec;37(12):2256-63. doi: 10.1007/s00259-010- ... Dipyridamole myocardial blood flow (MBF) was assessed using 99mTc-sestamibi by measuring first-transit counts in the pulmonary ... artery and myocardial count rate from G-SPECT images. Baseline MBF was estimated 2 h later according to the same procedure. ... Results: Three pHPT patients showed reversible perfusion defects and were excluded from the analysis. In the remaining 19, CFR ...
Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, Processing, and Interpretation ... Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, ... Image Processing, Computer-Assisted / methods* * Myocardial Perfusion Imaging* / instrumentation * Myocardial Perfusion Imaging ...
myocardial perfusion imaging. Myocardial perfusion imaging with nuclear tracers is well established in the diagnosis and ... Prognostic value of myocardial perfusion imaging: state of the art and new developments. J Nucl Cardiol. 1996;3(6 part 1):516- ... Prognostic Value of Automated Quantification of 99mTc-Sestamibi Myocardial Perfusion Imaging William D. Leslie, Shawn A. Tully ... Prognostic Value of Automated Quantification of 99mTc-Sestamibi Myocardial Perfusion Imaging Message Subject (Your Name) has ...
Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC- ... myocardial perfusion imaging.. Methods: This prospective open label clinical trial will include 71 consecutive patients with ... Myocardial SPECT imaging will be performed in all patients at 1-month follow-up after the TAVI procedure. Targeted PCI will be ... The primary endpoint is a composite of periprocedural myocardial infarction [ Time Frame: 6 months ]. Perprocedural myocardial ...
The difference in the area and degree of 99mTc-MIBI myocardial perfusion defects at rest in patients with heart failure caused ... The aim of our investigation was to assess a differential diagnostic value of resting 99mTc-MIBI myocardial perfusion defects ... of myocardial perfusion defects (AMPD and DMPD) at rest in regions supplied by three coronary arteries were evaluated in all ... The area of perfusion defects in the left anterior descending (LAD) and right coronary artery (RCA) regions in dilative ...
Buy the Hardcover Book CT Imaging of Myocardial Perfusion and Viability by U. Joseph Schoepf at Indigo.ca, Canadas largest ... time-resolved CT imaging of myocardial perfusion: Dual-source CT.- Dynamic, time-resolved CT imaging of myocardial perfusion: ... CT assessment of myocardial viability: Quantitative imaging.- Clinical Implementation: CT myocardial perfusion imaging: ... CT Imaging of Myocardial Perfusion and Viability: Beyond Structure and Function. EditorU. Joseph Schoepf, Fabian Bamberg, ...
Laser Doppler imaging of myocardial perfusion during coronary bypass surgery Author(s): Karin Wardell; Ulf Hermansson; Gert E. ... Laser Doppler perfusion imaging has been used to assess the myocardium perfusion on the arrested heart during bypass surgery. ... In conclusion, laser Doppler perfusion imaging can easily be used intraoperatively in conjunction with bypass surgery. It ... The anticipated perfusion increase following declamping of the internal thoracic artery was investigated by mapping areas at ...
Abstract 1970: Combined Coronary Artery Imaging, Myocardial Perfusion and Delayed Enhancement in Patients With Suspected ... Abstract 1970: Combined Coronary Artery Imaging, Myocardial Perfusion and Delayed Enhancement in Patients With Suspected ... Abstract 1970: Combined Coronary Artery Imaging, Myocardial Perfusion and Delayed Enhancement in Patients With Suspected ... Abstract 1970: Combined Coronary Artery Imaging, Myocardial Perfusion and Delayed Enhancement in Patients With Suspected ...
"Myocardial Perfusion Imaging" by people in this website by year, and whether "Myocardial Perfusion Imaging" was a major or ... "Myocardial Perfusion Imaging" by people in Profiles.. * Masrur S, Memon S, Chhabra L, Parker MW, Duvall L. SPECT Myocardial ... "Myocardial Perfusion Imaging" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Analysis of myocardial perfusion from vasodilator stress computed tomography: does improvement in image quality by iterative ...
The significance of ischemic ECG changes during adenosine infusion in patients with normal myocardial perfusion imaging (MPI) ... The significance of ischemic ECG changes during adenosine infusion in patients with normal myocardial perfusion imaging (MPI) ... 20535597 - Patients with adenosine-induced st-segment depressions and normal myocardial perfusion .... 20599017 - Prevalence ... During a 24 ± 13 month follow-up period, there were no deaths or myocardial infarctions, while an eleventh patient underwent ...
  • Evidence of recent and not-so-recent myocardial infarcts will be visible, but most persons with coronary heart disease who have not had a previous infarction will have normal perfusion patterns when they are at rest. (britannica.com)
  • the substance is injected while the individual is exercising so that areas of transient ischemia (temporary reduction in blood flow to the heart) can be identified and the patient treated to prevent myocardial infarction. (britannica.com)
  • It can also detect regions of myocardial infarction by showing areas of decreased resting perfusion. (wikipedia.org)
  • Similarly, if tissue damage (heart attack, myocardial infarction, cardiac stunning or hibernation) is to be determined, this is done under "resting" conditions. (wikipedia.org)
  • Clinical values of left ventricular mechanical dyssynchrony assessment by gated myocardial perfusion SPECT in patients with acute myocardial infarction and multivessel disease. (springer.com)
  • Over the years, both the equipment (second harmonic, pulsed power etc.) and the contrast agents (stability, dimension of microbubbles, etc) have been progressively improved in such a way that nowadays, it is realistic to envisage the use of contrast echocardiography to assess myocardial perfusion either in baseline condition (myocardial infarction, etc) or during stress. (escardio.org)
  • Twenty one consecutive first-pass adenosine stress perfusion MR data sets interpreted positive for ischemia or infarction were processed by non-rigid Registration followed by KLT filtering. (scirp.org)
  • Acute myocardial infarction or cardiac death occurred in 79 individuals (11.0% of the cohort). (snmjournals.org)
  • Visual and quantitative categorization of scan perfusion abnormalities showed similar prognostic value for predicting acute myocardial infarction or cardiac death. (snmjournals.org)
  • The primary outcome criterion is a composite criterion of feasibility and safety including all causes of death, stroke, major bleedings, major vascular complications, per procedural myocardial infarction, coronary revascularization or rehospitalisation for cardiac cause at 6 month follow-up. (clinicaltrials.gov)
  • Introduction: MRI offers a combination of functional studies for the detection of ischemia, detection and quantification of myocardial infarction as well as coronary angiography. (ahajournals.org)
  • Analysis of these images provides important prognostic and diagnostic information, and accurately determines the extent and location of myocardial ischemia and/or infarction. (renalandurologynews.com)
  • The major strength of the technique is its ability to provide powerful prognostic information in a wide range of patient populations, including patients with known CAD, at high risk for CAD, post-myocardial infarction, diabetes, advanced age, obesity, and women. (renalandurologynews.com)
  • and (4) patients who have had recent myocardial infarction who did not undergo an early cardiac catheterization and reperfusion treatment strategy. (renalandurologynews.com)
  • The primary endpoint was the incidence of nonfatal myocardial infarction (MI) and cardiac death. (diabetesjournals.org)
  • or if all patients had had previous myocardial infarction. (acpjc.org)
  • Perioperative cardiac events occurred in 19 patients, including 5 with cardiac death, 7 with nonfatal myocardial infarction and 7 with unstable angina. (onlinejacc.org)
  • Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. (semanticscholar.org)
  • Background: It is of great clinical importance to exclude myocardial infarction in patients with suspected coronary artery disease who do not have stress-induced ischemia. (lu.se)
  • The diagnostic use of myocardial perfusion single-photon emission computed tomography (SPECT) in this situation is sometimes complicated by attenuation artifacts that mimic myocardial infarction. (lu.se)
  • Methods: In this study, 52 patients without known prior infarction and no stress-induced ischemia on SPECT imaging were examined in both supine and prone position. (lu.se)
  • The results were compared with cardiac magnetic resonance imaging (CMR) with delayed-enhancement technique to confirm or exclude myocardial infarction. (lu.se)
  • None of the 37 defects were associated with myocardial infarction by CMR, indicating that all of them represented attenuation artifacts. (lu.se)
  • the remaining 24 had no sign of ischemic infarction but 2 had other kinds of myocardial injuries. (lu.se)
  • Conclusion: Perfusion defects in the supine position that disappeared in the prone position were caused by attenuation, not myocardial infarction. (lu.se)
  • There were 9 (21.9%) cases of angina, 2 (4.9%) cases of revascularization and 4 (9.8%) cases of myocardial infarction. (wits.ac.za)
  • Nuclear cardiology studies are used to assess myocardial blood flow, evaluate the heart's pumping function, and visualize the size and location of a myocardial infarction. (medscape.com)
  • The diagnostic information is generated by provoking controlled regional ischemia in the heart with variable perfusion. (wikipedia.org)
  • The second Speaker (Dr Mazzanti from Ancona - Italy) underlined the enormous amount of data available on the value of SPECT imaging in the field of CAD for the detection of inducible ischemia, viability, ventricular function, etc. (escardio.org)
  • Evaluation of a strategy of selected revascularization guided on myocardial ischemia detection after the TAVI procedure by using single photon emission computed tomography (SPECT) myocardial perfusion imaging. (clinicaltrials.gov)
  • Hypothesis: An alternative management of CAD guided by significant myocardial ischemia detection after TAVI could reduce the risk of unnecessary revascularization, the complications and the costs inherent to these procedures and a phase II trial is requiring to the evaluate this innovative and less invasive strategy. (clinicaltrials.gov)
  • Correlation of echocardiographic left atrial abnormality with myocardial ischemia during myocardial perfusion assessment in patients with left bundle branch block. (umassmed.edu)
  • Myocardial Perfusion Imaging for Evaluation and Triage of Patients with Suspected Acute Cardiac Ischemia: A Randomized Controlled Trial. (acc.org)
  • Conversely, the presence of angina in patients with aortic stenosis is less specific for coronary obstructive disease, since chest pain could be a result of increased myocardial wall stress, increased oxygen demand, or subendocardial ischemia. (springer.com)
  • Cardiac magnetic resonance (CMR) and cardiac computer tomography (CCT) myocardial imaging give us more precise imaging with an improved special resolution which can depict subendocardial ischemia. (benthamscience.com)
  • CMR is a rapidly developing new modality with applications in clinical cardiology for detection and assessment of myocardial ischemia and viability. (elsevier.com)
  • CMR perfusion results for the detection of ischemia in comparison with stress echocardiography and scintigraphic techniques are reasonable, but all the studies reported to date have been conduced in selected patients. (elsevier.com)
  • Myocardial perfusion imaging (MIBI) mainly aims to detect cardiac ischemia and viability. (chulacardiaccenter.org)
  • Given that the in-plane resolution achieved with most CMR "first-pass" perfusion studies averages currently between 2 to 3 mm, a pixel-wise measurement is commensurate with the requirements for detecting subendocardial ischemia. (onlinejacc.org)
  • Sixty-nine patients, 44 men and 25 women, age 61 ± 10 years (range 35-82), with a clinical suspicion of stress induced myocardial ischemia, were investigated. (biomedcentral.com)
  • Myocardial ischemia is a disorder that is usually caused by a critical coronary artery obstruction, which is also known as atherosclerotic coronary artery disease (CAD). (medscape.com)
  • Diagnosing myocardial ischemia prior to a heart attack is important. (medscape.com)
  • Myocardial perfusion imaging under rest and/or exercise or pharmacologic stress conditions to delineate regions of reversible myocardial ischemia or infarcted myocardium in patients with known or suspected coronary artery disease . (rxlist.com)
  • Among these, patients who had no evidence of reversible ischemia and had hyperdynamic left ventricle on perfusion imaging, were selected and their recent echocardiograms were reviewed for evidence of diastolic dysfunction. (scipedia.com)
  • The diagnostic and prognostic utility of gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in patients with suspected or known coronary artery disease (CAD) is well established. (springer.com)
  • To assess the feasibility of exercise perfusion computed tomography (CT) in patients suspected of having hemodynamically significant coronary stenosis. (nih.gov)
  • The primary outcome measure is to establish whether 320-multidetector computed tomography can identify myocardial perfusion defects as compared to the gold standards of 3Tesla magnetic resonance imaging and fractional flow reserve measured during invasive coronary angiography. (clinicaltrials.gov)
  • Our secondary outcome measures are to assess the performance of 320-multidetector computed tomography in the detection of regional wall motion abnormalities in comparison to those obtained with 3Tesla cardiac magnetic resonance imaging. (clinicaltrials.gov)
  • Computed tomography will be performed using a 320 multidetector computed tomography scanner and may include coronary calcium score, coronary angiography and imaging of myocardial perfusion, function and viability. (clinicaltrials.gov)
  • According to the most recent appropriate use criteria for cardiac radionuclide imaging (described in indications 6 to 9 of Table 1 of Hendel and colleagues' guideline [1]) and cardiac computed tomography (described in indications 6 to 8. (annals.org)
  • Levsky JM, Travin MI, Haramati LB. Coronary Computed Tomography Angiography Versus Radionuclide Myocardial Perfusion Imaging. (annals.org)
  • Analysis of myocardial perfusion from vasodilator stress computed tomography: does improvement in image quality by iterative reconstruction lead to improved diagnostic accuracy? (umassmed.edu)
  • After the injection of the radiopharmaceutical, images are obtained using a nuclear camera using a technique called single photon emission computed tomography (SPECT) or positron emission tomography (PET). (renalandurologynews.com)
  • 7 ) ushered in what was viewed by many to be a bright new era for MCE, demonstrating in humans the concordance between stress MCE and single-photon emission computed tomography images. (onlinejacc.org)
  • Methods: We searched Medline and Embase for literature that evaluated stress MPI for the diagnosis of obstructive CAD using magnetic resonance imaging (MRI), contrast-enhanced echocardiography (ECHO), single-photon emission computed tomography (SPECT) and positron emission tomography (PET). (harvard.edu)
  • 4 Potential additional screening tests include computed tomography scanning for coronary calcium, exercise or pharmacological stress imaging, and carotid ultrasound examination. (diabetesjournals.org)
  • Therefore, with the combination of vasodilator SPECT or PET imaging and cardiac computed tomography, we can achieve an accurate non-invasive assessment of the coronaries and proceed with cardiac catheterization only in patients with significant ischemic burden, which is estimated to be less than 50% of the patients. (springer.com)
  • The objective of this study was to assess the incremental value of myocardial wall motion and thickening compared with perfusion alone obtained from gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in diagnosing myocardial viability in patients with ischemic heart failure. (physiciansweekly.com)
  • A 17 segment model has become the standard for interpreting myocardial perfusion single photon emission computed tomography (SPECT). (pubmedcentralcanada.ca)
  • In this multicenter study the comparative safety and diagnostic efficacy of single-photon emission computed tomography (SPECT) thallium imaging during adenosine-induced coronary hyperemia was compared with exercise treadmill stress. (onlinejacc.org)
  • Myocardial perfusion imaging (MPI) using single-photon emission computed tomography (SPECT) agents has demonstrated high accuracy for the detection of clinically relevant stenoses. (uni-wuerzburg.de)
  • Advantages of PET include more reliable quantification of absolute myocardial blood flow, the routine use of computed tomography for attenuation correction, a higher spatiotemporal resolution and a higher count sensitivity. (uni-wuerzburg.de)
  • Myocardial perfusion imaging (MPI) has evolved from planar scintigraphy to single detector single-photon emission computed tomography (SPECT) imaging, to dual detector SPECT imaging to our present state of multiple (more than two) detector SPECT imaging. (imagewisely.org)
  • Rapid technological advance has brought many myocardial perfusion imaging (MPI) modalities other than myocardial single-photon emission computed tomography (SPECT) imaging. (benthamscience.com)
  • Objectives: This study evaluated the clinical significance of an isolated transient ischemic dilatation (TID) in the otherwise normal or relatively normal single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in determining the risk of future cardiac events. (wits.ac.za)
  • Myocardial perfusion imaging (MPI), using single photon emission computed tomography (SPECT) is a validated method for detecting coronary artery disease. (biomedcentral.com)
  • Three pHPT patients showed reversible perfusion defects and were excluded from the analysis. (nih.gov)
  • The aim of our investigation was to assess a differential diagnostic value of resting 99mTc-MIBI myocardial perfusion defects in evaluation of the etiology of heart failure. (mdpi.com)
  • The area and the degree (severity) of myocardial perfusion defects (AMPD and DMPD) at rest in regions supplied by three coronary arteries were evaluated in all the patients. (mdpi.com)
  • The area of perfusion defects in the left anterior descending (LAD) and right coronary artery (RCA) regions in dilative cardiomyopathy patients was smaller than in ischemic heart failure patients (1.43±0.9 vs 2.53±0.53, P =0.001, and 2.19±0.6 vs 2.82±0.56, P =0.02). (mdpi.com)
  • The degree of perfusion defects was also less severe in the same circulation regions (1.39±0.93 vs 2.59±0.6, P =0.01, and 1.6±0.46 vs 2.71±0.15, P =0.001). (mdpi.com)
  • The difference in the area and degree of 99m Tc-MIBI myocardial perfusion defects at rest in patients with heart failure caused by idiopathic dilative cardiomyopathy or ischemic heart failure is measurable and has a predictive value for differentiation of the etiology of global left ventricular systolic impairment. (mdpi.com)
  • The risk of perioperative cardiac events in patients undergoing noncardiac surgery has been related to the presence of transient defects on dipyridamole thallium-201 myocardial imaging, reflecting jeopardized viable myocardium. (onlinejacc.org)
  • Vasodilator stress (including regadenoson) MPI effectively risk stratifies patients with recently elevated cardiac biomarkers, with the increasing risk of mortality with the increasing severity of perfusion defects. (springermedizin.de)
  • Start Forskningsoutput Disappearance of myocardial perfusion defects on prone SPECT. (lu.se)
  • Results: There were 63 defects in supine-position images, 37 of which disappeared in the prone position. (lu.se)
  • Nevertheless, it can be argued that the Achilles heel of CMR perfusion imaging is not the random noise, but rather the artifacts that can mimic perfusion defects ( 2 ). (onlinejacc.org)
  • specifically whether frequency-offsets could cause substantial image degradation and subendocardial dark rim artefacts (DRA) mimicking real perfusion defects in vivo and hindering diagnostic quality. (biomedcentral.com)
  • The evaluation of stress-induced myocardial perfusion defects by non-invasive myocardial perfusion imaging (MPI) modalities has a leading role in the identification of coronary artery disease, and has excellent diagnostic and prognostic value. (scienceopen.com)
  • In addition to myocardial perfusion and left ventricular (LV) function, gated SPECT allows the assessment of mechanical asynchrony that may occur during contraction or relaxation. (springer.com)
  • Onset of left ventricular mechanical contraction as determined by phase analysis of ECG-gated myocardial perfusion SPECT imaging: Development of a diagnostic tool for assessment of cardiac mechanical dyssynchrony. (springer.com)
  • Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging. (springer.com)
  • Long-term prognostic value of left ventricular dyssynchrony assessment by phase analysis from myocardial perfusion imaging. (springer.com)
  • Left ventricular systolic and diastolic dyssynchrony as assessed by multi-harmonic phase analysis of gated SPECT myocardial perfusion imaging in patients with end-stage renal disease and normal LVEF. (springer.com)
  • Quantitative gated SPECT-derived phase analysis on gated myocardial perfusion SPECT detects left ventricular dyssynchrony and predicts response to cardiac resynchronization therapy. (springer.com)
  • On single-photon emission CT myocardial perfusion (SPECT) wall motion images, the left ventricular chamber was noted to have a peculiar 'spade-shaped' contour (Figure 1B,C, online supplementary media clip 1). (bmj.com)
  • Impact of contrast echocardiography on accurate discrimination of specific degree of left ventricular systolic dysfunction and comparison with cardiac magnetic resonance imaging. (bioportfolio.com)
  • Two such agents (Definity [Lantheus Medical Imaging, North Billerica, Massachusetts] and Optison [GE Healthcare, Princeton, New Jersey]) are approved by the U.S. Food and Drug Administration (FDA) and are commercially available for left ventricular cavity opacification in patients with technically difficult echocardiograms. (onlinejacc.org)
  • ANDARIS QUANTISON U.S. PHASE II TRIAL TO ASSESS MYOCARDIAL PERFUSION as well as left ventricular opacification, the Nottingham, U.K.-based biotech company said. (informa.com)
  • In particular, we summarise the role of left ventricular geometry indices for remodelling, phase analysis parameters to evaluate mechanical dyssynchrony, the concept of relative flow reserve in the evaluation of flow-limiting epicardial stenosis, vascular age and epicardial adipose tissue as early markers of atherosclerotic burden, and emerging parameters for the evaluation of myocardial innervation, such as the total defect score. (scienceopen.com)
  • Red blood cells can be radioactively labeled and imaged in the heart to give accurate and reproducible estimates of left ventricular ejection fraction for serial monitoring during potentially cardiotoxic chemotherapies for cancer. (reliasmedia.com)
  • This allows us to evaluate both myocardial perfusion and left ventricular function in one exam. (mic.ca)
  • Prevalence and predictors of left intraventricular dyssynchrony determined by phase analysis in patients undergoing gated SPECT myocardial perfusion imaging. (springer.com)
  • Incremental value of myocardial wall motion and thickening to perfusion alone by gated SPECT myocardial perfusion imaging for viability assessment in patients with ischemic heart failure. (physiciansweekly.com)
  • The American Society of Nuclear Cardiology (ASNC) has published an updated consensus statement on evidence-based treatment of stress myocardial perfusion imaging (MPI) in women. (prweb.com)
  • The consensus statement, "Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease-state-of-the-art evidence and clinical recommendations," is intended to guide appropriate use of nuclear cardiology in the evaluation of women presenting with symptoms consistent with stable ischemic heart disease (SIHD). (prweb.com)
  • ASNC's members are comprised of cardiologists, radiologists, physicians, scientists, technologists, imaging specialists and other professionals committed to the science and practice of nuclear cardiology. (prweb.com)
  • Because myocardial perfusion imaging increases the diagnostic accuracy of stress testing, the American College of Cardiology and American Heart Association (ACC/AHA) guidelines recommend that it be used in several patient subsets. (medscape.com)
  • The American Society of Nuclear Cardiology (ASNC) has issued a goal of reducing radiation doses to 9 mSv or lower in 50% of myocardial perfusion imaging (MPI) studies by 2014. (physiciansweekly.com)
  • Stress myocardial perfusion imaging is a nuclear cardiology procedure that is widely used to assess patients with known or suspected coronary artery disease. (renalandurologynews.com)
  • The most detailed criteria available to select patients for this procedure are the "Appropriate Use Criteria for Cardiac Radionuclide Imaging" that is published by the American College of Cardiology and other cardiology or imaging societies. (renalandurologynews.com)
  • Sheri D. Harrison, Mark A. Harrison and W. Lane Duvall, "Stress Myocardial Perfusion Imaging in the Emergency Department - New Techniques for Speed and Diagnostic Accuracy", Current Cardiology Reviews (2012) 8: 116. (eurekaselect.com)
  • Erratum to: ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers. (springermedizin.de)
  • and †Division of Cardiology and ‡Department of Radiology and Biomedical Imaging, Section of Nuclear Medicine, University of California, San Francisco, CA. (ovid.com)
  • Recently, the American Society of Nuclear Cardiology published an information statement 7 recommending that laboratories use imaging protocols that achieve on average a radiation exposure of less than or equal to 9 mSv in 50% of the studies by 2014. (imagewisely.org)
  • Myocardial Perfusion Imaging was designed by Nuclear Medicine Technologists for Nuclear Medicine Technologists who routinely perform nuclear cardiology procedures, but is an excellent course for any healthcare professional caring for patients with cardiovascular disease. (echeloned.com)
  • Lou has a strong background in Nuclear Cardiology and is a Nuclear Medicine, PET/CT Technologist at Lake Medical Imaging in Leesburg FL. (echeloned.com)
  • Among the techniques of nuclear cardiology, myocardial perfusion imaging is the most widely used. (medscape.com)
  • Myocardial Perfusion Imaging is a form of Nuclear Cardiology. (trilliumhealthpartners.ca)
  • Nuclear cardiology studies employ non-invasive techniques for assessing myocardial blood flow, the heart's pumping function, and also to identify the size and location of the damaged heart tissue. (azheartdoctor.com)
  • Myocardial perfusion imaging (MPI) is the most widely used nuclear cardiology technique that deals with the assessment of blood flow to the heart (the myocardium). (azheartdoctor.com)
  • The third speaker (P. Nihoyannopoulos from London - UK) nicely reported to the audience the extreme flexibility of Echocardiography and the added values of ultrasound contrast agent (microbubbles) which can be used either to further increase the quality of images with the aim of a better definition of endocardial borders or to evaluate myocardial perfusion. (escardio.org)
  • Finally, the speaker opened the new window of 3D Echocardiography which looks extremely promising for the evaluation of regional myocardial perfusion partially reducing the operator dependency in acquiring images. (escardio.org)
  • Contrast-Enhanced Stress Echocardiography and Myocardial Perfusion Imaging in Patients Hospitalized With Chest Pain: A Randomized Study. (bioportfolio.com)
  • Ultrasound contrast-enhanced stress echocardiography improves endocardial visualization, but diagnostic test rates versus stress myocardial perfusion imaging (MPI) have not been studied. (bioportfolio.com)
  • Hospitalized patients referred for noninvasive stress imaging were randomized 1:1 to stress echocardiography or stress MPI. (bioportfolio.com)
  • The objective of this study is to determine whether myocardial contrast echocardiography in patients with cardiomyopathy (HCM) can detect resting hypo-perfusion due to fibrosis or stress i. (bioportfolio.com)
  • The literature is replete with studies showing the promise of myocardial contrast echocardiography (MCE) for CAD detection ( 1,2 ). (onlinejacc.org)
  • To use quantitative myocardial contrast echocardiography (MCE) and strain rate imaging (SRI) to assess the role of microvascular disease in subclinical diabetic cardiomyopathy. (bmj.com)
  • However, dobutamine stress echocardiography (DSE) and vasodilator myocardial perfusion imaging have comparable characteristics. (acpjc.org)
  • Cardiovascular magnetic resonance imaging (MRI) and tissue Doppler echocardiography (TDE) were recently shown to be more sensitive than conventional methods for the respective assessment of myocardial perfusion and contractility. (eurekamag.com)
  • LVEF ≥ 70%) on stress radionuclide myocardial perfusion imaging (RNMPI), are more likely to have features of diastolic dysfunction on transthoracic echocardiography. (scipedia.com)
  • Mukherjee A, Patel CD, Naik N, Sharma G, Roy A. Quantitative assessment of cardiac mechanical dyssynchrony and prediction of response to cardiac resynchronization therapy in patients with nonischaemic dilated cardiomyopathy using gated myocardial perfusion SPECT. (springer.com)
  • Furthermore, he also mentioned the capability of SPECT to obtain quantitative measurements of myocardial perfusion as clearly shown by different groups. (escardio.org)
  • After many years, in fact, PET is still the only method systematically used for evaluating myocardial Blood Flow in a quantitative manner (ml/min/g). (escardio.org)
  • Similarly, diverse CT approaches for the assessment of myocardial viability are described, with careful consideration of the available experimental and clinical evidence and the role of quantitative imaging. (springer.com)
  • Conclusion: Quantitative evaluation of cardiac MR perfusion data needs to account for signal saturation in both the LV blood pool and the myocardium. (mdc-berlin.de)
  • Although human interpretation of 99m Tc-sestamibi SPECT myocardial perfusion imaging has been repeatedly validated in the diagnostic and prognostic assessment of coronary artery disease, it remains unclear if automated computer-derived quantitative indices of perfusion have similar or independent prognostic information. (snmjournals.org)
  • The SPECT studies were initially interpreted visually without benefit of computer-based analysis and were then subjected to a blinded reprocessing to extract quantitative indices of perfusion. (snmjournals.org)
  • More recently, computer software has emerged for computing the SSS with minimal operator intervention, and we have previously reported close agreement between the visual and quantitative assessments of perfusion ( 3 ). (snmjournals.org)
  • Quantitative MCE shows that patients with diabetes but no evidence of obstructive coronary artery disease have impaired MBF reserve, but abnormal transmural flow and subclinical longitudinal myocardial dysfunction are not related. (bmj.com)
  • However, the feasibility and potential clinical utility of quantitative 3D perfusion measurements, as already shown with 2D-perfusion CMR and positron emission tomography, has yet to be evaluated. (uzh.ch)
  • The purpose of this study was to establish the feasibility of quantitative 3D-perfusion CMR for the detection of coronary artery disease (CAD) and to compare systolic and diastolic estimates of MBF. (uzh.ch)
  • Conclusions Quantitative 3D-perfusion CMR is feasible. (uzh.ch)
  • The aim of this study was to introduce the concept of the perfusion vector as a new objective quantitative method for further assisting the visual interpretation and to test the concept using simulated MPS images as well as patients. (lu.se)
  • Fourteen days of treatment with nifedipine simultaneously improves myocardial perfusion and function, as evaluated by highly sensitive and quantitative methods. (eurekamag.com)
  • Quantitative analysis of perfusion values showed that GC-PET uptake was significantly lower than FR-PET uptake in 67.6% of segments. (sinapse.ac.uk)
  • time intensity curves (TIC) of these CER images were used for semi-quantitative analysis. (biomedcentral.com)
  • Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (myocardium). (wikipedia.org)
  • Feasibility of dynamic CT-based adenosine stress myocardial perfusion imaging to detect and differentiate ischemic and infarcted myocardium in an l. (nih.gov)
  • The purpose of the study is feasibility of dynamic CT perfusion imaging to detect and differentiate ischemic and infarcted myocardium in a large porcine model. (nih.gov)
  • In a large animal model, CT-derived parameters of myocardial perfusion may enable detection and differentiation of ischemic and infarcted myocardium. (nih.gov)
  • SNR and CNR were measured in abnormal and normal myocardium in unfiltered and KLT filtered images following nonrigid registration to compensate for respiratory and other motions. (scirp.org)
  • Laser Doppler perfusion imaging has been used to assess the myocardium perfusion on the arrested heart during bypass surgery. (spie.org)
  • The larger images allowed quantification of blood flow in different regions of the myocardium. (spie.org)
  • The creation and display of functional images showing where the blood is flowing into the MYOCARDIUM by following over time the distribution of tracers injected into the blood stream. (umassmed.edu)
  • Myocardial Bridging (MB) refers to the band of myocardium that abnormally overlies a segment of a coronary artery. (bioportfolio.com)
  • The multivariate regression analysis showed that the model that combined myocardial perfusion uptake with wall motion and thickening scores had the optimal predictive efficiency to distinguish hibernating myocardium from scar in the segments with decreased perfusion. (physiciansweekly.com)
  • Assessment of myocardial wall motion and thickening in addition to conventional perfusion uptake in the segments with decreased perfusion enables better differentiation of hibernating myocardium from scar in patients with ischemic heart failure. (physiciansweekly.com)
  • Early in the history of SPECT perfusion imaging a 20-segment model was widely employed, but was later felt to over-represent the apical segments of the myocardium. (pubmedcentralcanada.ca)
  • This study was undertaken to test the hypothesis that the risk of perioperative cardiac events is not simply determined by the presence of myocardium at risk, but is directly related to the extent of myocardium at risk as reflected in thallium-201 myocardial imaging. (onlinejacc.org)
  • The probability of important cardiac events in patients undergoing noncardiac surgery is best predicted by the extent of myocardium at risk as reflected on thallium·201 myocardial perfusion imaging. (onlinejacc.org)
  • In particular, the myocardium defect in the MP PET images had improved visual as well as contrast versus noise tradeoff. (elsevier.com)
  • A stress myocardial perfusion scan is used to assess the blood flow to the heart muscle (myocardium) when it is stressed by exercise or medication and to determine what areas of the myocardium have decreased blood flow. (trinitymedicalimaging.co.uk)
  • Myocardial Perfusion Imaging (MPI) is a diagnostic procedure used to show how well your heart muscle is being supplied (perfused) with blood at rest and under stress. (medmovie.com)
  • N. BILLERICA, Mass.--(BUSINESS WIRE)--Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic imaging, today presents Phase I data relating to the safety and tolerability in human subjects of BMS747158, its novel fluorine 18-labeled Positron Emission Tomography (PET) tracer for myocardial perfusion imaging. (biospace.com)
  • Purpose: Aim of the study was to evaluate the feasibility and diagnostic accuracy of the combination of stress (adenosine) perfusion (PERF), delayed enhancement (DE) and coronary angiography (MRCA). (ahajournals.org)
  • Four percent (2/54) of PERF and 15% of MRCAs (8/54) had non diagnostic image quality. (ahajournals.org)
  • The primary outcome was diagnostic test rate defined as interpretable images and achievement of >85% of age-predicted maximal heart rate (for dobutamine and exercise). (bioportfolio.com)
  • Objectives: To determine and compare the diagnostic performance of stress myocardial perfusion imaging (MPI) for the diagnosis of obstructive coronary artery disease (CAD), using conventional coronary angiography (CCA) as the reference standard. (harvard.edu)
  • Recent advances in camera technology, and changes to the imaging protocols have allowed MPI to become a more efficient way of providing this diagnostic information. (eurekaselect.com)
  • With stress-only imaging, rest images are eliminated if stress images are normal, as they provide no additional prognostic or diagnostic value and cancelling the rest images would shorten the length of the test which is of particular importance to the ED population. (eurekaselect.com)
  • The influence of systolic or diastolic acquisition on myocardial blood flow (MBF) estimates, diagnostic accuracy and image quality is also unknown for 3D-perfusion CMR. (uzh.ch)
  • Therefore, the safety, and the diagnostic and prognostic significances of vasodilator stress imaging have not been well studied in aortic stenosis and are not well established. (springer.com)
  • Pharmacologic stress with dipyridamole has provided useful diagnostic, as well as prognostic, information in patients undergoing thallium-201 myocardial perfusion imaging. (onlinejacc.org)
  • The study's authors conclude that using Corus CAD earlier in the diagnostic algorithm could reduce the number of invasive cardiac tests by more accurately evaluating the presence of obstructive coronary artery disease compared to the traditional algorithm of stress myocardial perfusion imaging (MPI) in these patients. (cardiodx.com)
  • With positron emission tomography (PET) becoming more widely available, mainly due to its diagnostic performance in oncology, perfusion imaging with that modality is more practical than in the past and overcomes existing limitations of SPECT MPI. (uni-wuerzburg.de)
  • Studies have shown that images from these solid state imagers using conventional myocardial perfusion imaging (MPI) doses of 10 mCi for rest and 30 mCi from stress acquired at four minutes for rest and two minutes for stress are of higher quality and at least of equal diagnostic value to those acquired on conventional two-detector SPECT cameras using 14 minutes for rest and 12 minutes for stress acquisition. (imagewisely.org)
  • PURPOSE: To determine whether the assessment of regional wall thickening (WT) in addition to myocardial perfusion from stress supine acquisitions could compensate for the lack of prone acquisition and the corresponding decrease in the diagnostic performance of SPECT myocardial perfusion imaging (MPI) in patients with known or suspected coronary artery disease (CAD). (inserm.fr)
  • The diagnostic performance of SPECT MPI was determined for various image sets including nongated supine images (supine NG), nongated combined prone and supine images (prone and supine NG) and gated supine images, allowing WT evaluation from NG images in addition to perfusion (supine NG + WT) using invasive coronary angiography and fractional flow reserve as the gold standards. (inserm.fr)
  • Whereas MPI is a valuable diagnostic tool, it is also a complex physiologic imaging process, which exposes it to several potential pitfalls and artifacts that can limit the utility of the study. (snmjournals.org)
  • Larger studies in patient populations reflecting a broader spectrum of disease are necessary before perfusion CMR can be envisaged as a clinically reliable and robust diagnostic tool. (elsevier.com)
  • Patient Centered Imaging In recent years, there has been a large increase in the role of diagnostic imaging in the medical industry and with that has come increased radiation exposure. (cardioserv.net)
  • Although introduced in 1990, myocardial first-pass perfusion imaging has not yet become a routine diagnostic tool, primarily because of insufficient image quality, insufficient coverage, and dark rim artifacts (DRA). (biomedcentral.com)
  • MPI measures myocardial blood flow and is a diagnostic tool for coronary artery disease, the number one cause of death across the globe. (smartteleradiology.com)
  • The use of dual isotope imaging is very interesting because this imaging combines the use of thallium-201 with technetium-99m agents permitting optimal image resolution and simultaneous assessment of viability, all with an exam duration of approximately 20 minutes. (clinicaltrials.gov)
  • Recent research has identified the assessment of myocardial perfusion and viability as another promising CT application for the comprehensive diagnosis of coronary heart disease. (springer.com)
  • In recent years, several technetium 99m-labeled myocardial perfusion agents have been under investigation to determine their utility in assessing regional myocardial blood flow and cellular viability. (biomedsearch.com)
  • Studies have shown that 99mTc sestamibi uptake after reperfusion, preceded by varying periods of coronary occlusion, reflects the degree of myocardial salvage and viability. (biomedsearch.com)
  • Viability: Why are we interested in myocardial viability. (indigo.ca)
  • SPECT/PET myocardial viability was defined as the reference standard. (physiciansweekly.com)
  • Considering wide availability and high cost-effectiveness, regional myocardial function integrated with perfusion on gated SPECT MPI has great promise to become a clinical tool in the assessment of myocardial viability. (physiciansweekly.com)
  • With its unique ability to evaluate perfusion at the cellular level and to assess perfusion at peak exercise stress, MPI plays an important role in diagnosing cardiovascular disease, establishing prognosis, assessing the effectiveness of therapy, and evaluating viability. (snmjournals.org)
  • Signs of viability that can be observed by CMR are the absence of late gadolinium-based contrast enhancement in a myocardial region involved in a recent infarct, any sign of wall thickening at rest (which is detectable with high accuracy by CMR), wall thickening after stimulation by low-dose dobutamine, and preserved wall thickness. (elsevier.com)
  • Judd, Robert M. / MR imaging of myocardial perfusion and viability . (elsevier.com)
  • In patients with ischemic heart disease who undergo revascularization based on PET viability assessment with fludeoxyglucose F-18 (F-18 FDG), those with a low myocardial perfusion reserve were at an increased risk of adverse cardiac events. (medscape.com)
  • However, no study compares stress thallium-201/rest technetium-99m sequential dual isotope high-speed myocardial perfusion imaging versus invasive coronary angiography. (clinicaltrials.gov)
  • The investigators report here the first validation of high-speed protocol with dual isotope for myocardial perfusion imaging using invasive coronary angiography as the standard of reference. (clinicaltrials.gov)
  • A single-center trial was undertaken in 165 consecutive, symptomatic patients with either known or suspected coronary disease and/or valve disease(VHD) who agreed to undergo cardiac catheterization and coronary angiography if stress myocardial perfusion imaging was abnormal. (medsci.org)
  • More recently, there seems to be renewed industry effort in pursuing approval of UCAs for the myocardial perfusion indication in Europe, and efforts in the U.S. have been initiated by another UCA manufacturer (Bracco Diagnostics, Milan, Italy) to pursue perfusion imaging-albeit of the liver-in radiologic indications. (onlinejacc.org)
  • List the indications and contraindications for myocardial perfusion imaging. (echeloned.com)
  • In fact, cardiac MR perfusion imaging is moving beyond traditional indications such as diagnosis of coronary disease to novel applications such as in congenital heart disease, where the imperatives of avoidance of ionizing radiation and achievement of high spatial resolution are of high priority. (thepreparedminds.com)
  • Patients with adenosine-induced ST-segment depressions and normal myocardial perfusion imaging: cardiac outcomes at 24 months. (biomedsearch.com)
  • BACKGROUND: The significance of ischemic ECG changes during adenosine infusion in patients with normal myocardial perfusion imaging (MPI) is controversial. (biomedsearch.com)
  • The preferred pharmacologic stressors for myocardial perfusion imaging are the coronary vasodilators dipyridamole, adenosine, and regadenoson. (renalandurologynews.com)
  • Eligible participants were randomly assigned to either receive screening with adenosine-stress radionuclide myocardial perfusion imaging (MPI) or receive no screening. (diabetesjournals.org)
  • With its ultrashort half-life and a potent and consistent vasodilator effect, adenosine may be the coronary vasodilator of choice with myocardial perfusion imaging. (onlinejacc.org)
  • Thus, the results of adenosine SPECT imaging are highly concordant with exercise SPECT thallium imaging. (onlinejacc.org)
  • Adenosine SPECT thallium imaging provides a safe and highly accurate imaging mode for the detection of coronary artery disease. (onlinejacc.org)
  • TTDE was performed at rest and during adenosine stress for myocardial scintigraphy. (biomedcentral.com)
  • ASNC is the recognized leader in quality, education, advocacy and standards in cardiovascular imaging, with more than 4,000 members worldwide. (prweb.com)
  • ASNC establishes standards for excellence in cardiovascular imaging through the development of clinical guidelines, professional education, advocacy and research development. (prweb.com)
  • Approaches to enhancing radiation safety in cardiovascular imaging: a scientific statement from the American Heart Association. (medscape.com)
  • Purpose: To determine the regime of linear contrast enhancement in human first-pass perfusion cardiovascular magnetic resonance (CMR) imaging to improve accuracy in myocardial perfusion quantification. (mdc-berlin.de)
  • Message Body (Your Name) thought you would like to see this page from the JACC: Cardiovascular Imaging web site. (onlinejacc.org)
  • Background Two-dimensional (2D) perfusion cardiovascular magnetic resonance (CMR) remains limited by a lack of complete myocardial coverage. (uzh.ch)
  • European Heart Journal - Cardiovascular Imaging, 19(9), 1019-1025. (deepdyve.com)
  • 8 - 22 ) Since its inception in 1993 the Duke Cardiovascular Databank has used a 12-segment model for assessing myocardial perfusion. (pubmedcentralcanada.ca)
  • International Journal of Cardiovascular Imaging (2019) 35: 569. (uni-wuerzburg.de)
  • Application of cardiac molecular imaging using positron emission tomography in evaluation of drug and therapeutics for cardiovascular disorders. (semanticscholar.org)
  • Myocardial perfusion imaging (MPI) is an important imaging modality in the management of patients with cardiovascular disease. (snmjournals.org)
  • Myocardial perfusion imaging (MPI) is a valuable tool in the management of patients with cardiovascular disease. (snmjournals.org)
  • Perfusion vector-a new method to quantify myocardial perfusion scintigraphy images: a simulation study with validation in patients. (lu.se)
  • The interpretation of myocardial perfusion scintigraphy (MPS) largely relies on visual assessment by the physician of the localization and extent of a perfusion defect. (lu.se)
  • Myocardial perfusion scintigraphy: the evidence. (springermedizin.de)
  • Renal perfusion is a term used to describe blood flow to the kidneys and is commonly assessed with a test called renal scintigraphy. (reference.com)
  • This document should help to improve patterns of care and clinical outcomes for the large sector of women requiring stress imaging procedures," said Leslee Shaw, PhD. (prweb.com)
  • 1564. How Good is Qualitative Analysis of 1st Pass Gd-DTPA Multislice Myocardial Perfusion Imaging for Clinical Evaluation? (ismrm.org)
  • 1565. Clinical Application of Myocardial Perfusion Post PTCA with SE-EPI, F.B. Gao, Y.G. Gao, B.S. Qiu, Y. Liang, Y.Q. Cai and X.Y. Ma, PLA General Hospital and GE Medical Systems China, Beijing, China. (ismrm.org)
  • Indeed, recent clinical validation studies of CZT technology have documented a scan time reduction and low radiation dose without degradation of myocardial perfusion imaging in comparison with standard dual detector cameras. (clinicaltrials.gov)
  • The fourth speaker (Dr Schindler form Geneva - Switzerland) had the responsibility of defending Positron Emission Tomography (PET) which is considered the gold standard in the clinical evaluation of myocardial perfusion. (escardio.org)
  • This article discusses mechanisms of cardiac dyssynchrony, reviews clinical data supporting resynchronization therapy, and addresses the lack of convincing evidence to support the use of noninvasive imaging measures of dyssynchrony in improving patient management. (springer.com)
  • The computational methods validated and optimised in the study have been integrated into a commercial MPI image reconstruction package, and are currently in clinical use in dozens of hospitals both in Finland and all over the world. (healthcanal.com)
  • The rapid but accurate triage of patients in an ED CPU is essential to their care, and stress-only imaging and new CZT cameras allow for shorter test time, lower radiation doses and lower costs while demonstrating good clinical outcomes. (eurekaselect.com)
  • The ability of clinical and thallium-201 imaging data to predict perioperative cardiac events was compared with stepwise multivariate logistic regression analysis. (onlinejacc.org)
  • PURPOSE: To investigate whether saturation using existing methods developed for 3T imaging is feasible for clinical perfusion imaging at 7T, and to propose a new design of saturation pulse train for first-pass myocardial perfusion imaging at 7T. (ox.ac.uk)
  • Both the telephone interviewer and the imaging analyst were blinded to the patients' clinical data. (wits.ac.za)
  • Join our movement to inspire excellence in imaging through accreditation, education and clinical development. (cardioserv.net)
  • For the first question, which pertains to the spatial resolution of perfusion maps, one can draw on ample evidence from experimental and clinical studies that demonstrate the benefits depicting myocardial perfusion with at least a resolution that is adequate to resolve blood flow deficits limited to the subendocardial layer. (onlinejacc.org)
  • The current review considers both the technical developments and the clinical experience with cardiac MR perfusion imaging, which hopefully demonstrates that it has long passed the stage of a research technique. (thepreparedminds.com)
  • We studied 718 patients referred for 99m Tc-sestamibi SPECT myocardial perfusion imaging who were followed for 5.6 ± 1.1 y (mean ± SD). (snmjournals.org)
  • The summed stress score (SSS) is a commonly used semiquantitative technique that combines the extent and severity of perfusion abnormalities into a single measure and has been shown to provide risk stratification in patients undergoing SPECT myocardial perfusion imaging ( 2 ). (snmjournals.org)
  • Masrur S, Memon S, Chhabra L, Parker MW, Duvall L. SPECT Myocardial Perfusion Imaging in the Diagnosis of Apical Hypertrophic Cardiomyopathy. (umassmed.edu)
  • Stress-only SPECT myocardial perfusion imaging: a review. (umassmed.edu)
  • Evaluating gender differences in prognosis following SPECT myocardial perfusion imaging among patients with diabetes and known or suspected coronary disease in the modern era. (umassmed.edu)
  • Within the last few years a 17-segment model has become the recommended standard for multiple cardiac imaging modalities and has been accepted by the ACC and ASNC for assessment of SPECT myocardial perfusion imaging. (pubmedcentralcanada.ca)
  • Mouden M, Rijkee KS, Schreuder N, Timmer JR, Jager PL. Influence of proton-pump inhibitors on stomach wall uptake of 99mTc-tetrofosmin in cadmium-zinc-telluride SPECT myocardial perfusion imaging. (springer.com)
  • Stress Electrocardiography vs Radionuclide Myocardial Perfusion Imaging among Patients Admitted for Chest Pain: Comparison of Teaching and Nonteaching Hospital Services. (bioportfolio.com)
  • EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision. (springermedizin.de)
  • The scan is usually performed in two phases involving a stress myocardial perfusion imaging scan and a rest myocardial perfusion imaging scan. (healthcanal.com)
  • Variability in normal myocardial blood flow measurements: physiologic, methodologic, or protocol related? (semanticscholar.org)
  • There was an overlap between groups which could be due to abnormal endothelial function in patients with normal myocardial perfusion having either hypertension or diabetes. (biomedcentral.com)
  • According to histopathology or microsphere measurements, 20 myocardial segments were classified as infarcted and 23 were ischemic (12 and 14 %, respectively). (nih.gov)
  • Myocardial perfusion abnormalities are the first sign of the ischemic cascade in the development of coronary artery disease (CAD). (bioportfolio.com)
  • Therefore, vasodilator stress imaging can be a valuable tool for the clinician in order to evaluate the ischemic burden and guide the revascularization strategy. (springer.com)
  • Eighty-three consecutive patients with ischemic heart failure who underwent both Tc-MIBI gated SPECT MPI and F-FDG positron emission tomography (PET) myocardial metabolic imaging were retrospectively enrolled. (physiciansweekly.com)
  • Hence, imaging in the prone position can help to rule out ischemic heart disease for some patients admitted for SPECT with suspected but not documented ischemic heart disease. (lu.se)
  • The myocardial enhancement ratio between stenotic and normally perfused territories was determined for each stenosis. (nih.gov)
  • Receiver operating characteristic curves were constructed to determine the myocardial enhancement ratio cutoff value. (nih.gov)
  • In the per-patient analysis, a myocardial enhancement ratio cutoff of 0.8 performed best for identifying functionally significant stenosis: Sensitivity was 95% (21 of 22 patients), specificity was 90% (nine of 10 patients), positive predictive value was 95% (21 of 22 patients), negative predictive value was 90% (nine of 10 patients), and accuracy was 94% (30 of 32 patients). (nih.gov)
  • Conclusion: The combination of PERF, DE and MRCA is feasible, combining stress perfusion and delayed enhancement yields the highest accuracy. (ahajournals.org)
  • As for CMR, T2 weighted imaging demonstrated edematous region without enhancement. (benthamscience.com)
  • Conversely, myocardial necrosis is characterized by signal enhancement of the infarct area after injection of Gd-DTPA, reduced wall thickness in chronic infarcts, and absence of a contractile reserve during dobutamine stimulation. (elsevier.com)
  • This study aims to develop a method for restoration and enhancement of dynamic PET images. (elsevier.com)
  • Conclusions: The proposed method is effective for restoration and enhancement of dynamic PET images. (elsevier.com)
  • 1 ), represent the myocardial contrast enhancement as a linear response to the contrast enhancement in the blood pool. (onlinejacc.org)
  • 4 ) demonstrated that with multivessel coronary artery disease, one should look with CMR beyond the visual detection of regional, contrast-enhancement deficits, and also quantify the myocardial perfusion reserve to significantly improve the detection of flow limiting coronary disease. (onlinejacc.org)
  • First-pass myocardial perfusion is often imaged with a tailored hybrid centric interleaved echo-planar-imaging sequence, providing rapid image acquisition with good contrast enhancement. (biomedcentral.com)
  • 7 ]. This phase-encode order was tailored for first-pass myocardial perfusion, minimising the effective time-of-echo (TE) thus minimising susceptibility dephasing of signal within pixels, especially during first-pass of a strong paramagnetic contrast agent (CA), and minimising blood flow artefacts, while providing a good CA enhancement. (biomedcentral.com)
  • Select myocardial frames during upslope (top row) and their corresponding pixel-wise contrast enhancement ratio (CER) maps. (biomedcentral.com)
  • Posted in Magnetic Resonance Imaging and tagged Coronary Artery Disease (CAD) , Delayed Contrast Enhancement (DCE) , Image Quality , Myocardial Perfusion Imaging (MPI) . (thepreparedminds.com)
  • Additional advantages of those radiotracers include, but are not limited to: potentially improved cost-effectiveness due to the use of pre-existing delivery systems and superior imaging qualities, mainly due to the shortest positron range among available PET MPI probes. (uni-wuerzburg.de)
  • The aim of this study was to examine the quality of nitrogen 13-labeled ammonia (NH3) perfusion data from coincidence-capable gamma camera positron emission tomography (GC-PET) systems compared with that from full-ring positron emission tomography (FR-PET). (sinapse.ac.uk)
  • What is the prognostic value of myocardial perfusion imaging using rubidium-82 positron emission tomography? (semanticscholar.org)
  • OBJECTIVES The objective was to determine the prognostic value of rubidium-82 (82Rb) positron emission tomography (PET) myocardial perfusion imaging (MPI). (semanticscholar.org)
  • Long-term prognostic value of 13N-ammonia myocardial perfusion positron emission tomography added value of coronary flow reserve. (semanticscholar.org)
  • Cardiac positron emission tomography imaging. (semanticscholar.org)
  • The assessment of myocardial perfusion and function using PET and hybrid positron emission tomography (PET)/CT imaging is becoming more available as the cost of the technology decreases and as positron-emitting radiopharmaceuticals become more available. (medscape.com)
  • What is the efficacy of myocardial perfusion imaging for cardiac assessment? (medscape.com)
  • 1560. Qualitative Magnetic Resonance Perfusion Imaging in Patients with Coronary Artery Disease, G.R. Cherryman, P.R. Sensky, A. Jivan, C. Reek and N.J. Samani, University of Leicester, Glenfield General Hospital NHS Trust, Leicester, UK. (ismrm.org)
  • [ 17 ] In a meta-analysis of 14 trials with over 12,000 patients, normal Tc-99m sestamibi imaging was associated with a cardiac event rate of 0.6% per year. (medscape.com)
  • CT myocardial perfusion imaging was performed within 1 minute after patients performed supine exercise on an ergometer secured to the CT table. (nih.gov)
  • The possibility to shorten the imaging time makes the scan easier for the patient and makes it possible to scan a larger number of patients during one day. (healthcanal.com)
  • For many patients, even the shortened imaging time is too long and they tend to move during the scan. (healthcanal.com)
  • Myocardial perfusion imaging with nuclear tracers is well established in the diagnosis and prognostic assessment of patients with known or suspected coronary artery disease (CAD) ( 1 ). (snmjournals.org)
  • The population for this retrospective analysis was selected from 1,027 consecutive patients who had nuclear perfusion stress testing performed at St. Boniface General Hospital between January 1, 1994, and April 20, 1999, on a single imaging system (Elscint 409). (snmjournals.org)
  • Patients were excluded if the scan was limited to planar images ( n = 3), if images could not be reprocessed due to corrupted archive media or poor-quality image data ( n = 104), or if all imaging was not complete on the designated camera ( n = 33). (snmjournals.org)
  • Myocardial SPECT imaging will be performed in all patients at 1-month follow-up after the TAVI procedure. (clinicaltrials.gov)
  • This approach could limit radiation doses by identifying patients with normal reads who would need only lose-dose stress imaging. (physiciansweekly.com)
  • Outpatients, inpatients, and ED patients at high risk for cardiac problems participated in a study and underwent stress/rest, rest/stress, or stress-only imaging. (physiciansweekly.com)
  • With this protocol, patients with normal reads on low-dose stress imaging may be able to avoid high-dose rest imaging. (physiciansweekly.com)
  • If only patients with very good image quality (IQ) in MRCA were analysed (n=17), sensitivity was increased with only little loss of specificity. (ahajournals.org)
  • The American Board of Internal Medicine Foundation's Choosing Wisely initiative has identified the routine use of stress cardiac imaging among lower-risk patients as an expensive test that should be q. (bioportfolio.com)
  • Selected lower risk patients may be candidates for this study as well, particularly if they cannot exercise or if the ECG is not interpretable (left bundle branch block, ventricular pacing, severe baseline ST segment abnormalities), since pharmacologic stress is required in these cases, and necessarily must be performed in conjunction with cardiac imaging. (renalandurologynews.com)
  • In this single-center randomized, controlled comparative effectiveness trial, 400 intermediate-risk patients (63% women, 54% Hispanic, 37% African-American) admitted to a telemetry floor were randomized to either CCTA or myocardial perfusion imaging (MPI) and followed for 40 months. (bmj.com)
  • In the evaluation of patients with chest pain, whether any imaging is warranted rather than exercise stress testing alone remains a pertinent question given the radiation exposure and costs associated with both CCTA and MPI. (bmj.com)
  • Emergency room evaluations of patients presenting with chest pain continue to rise, and these evaluations which often include cardiac imaging, are an increasing area of resource utilization in the current health system. (eurekaselect.com)
  • The goal of this study was to assess the safety and efficacy of resting myocardial perfusion imaging (MPI) (technetium Tc99m sestamibi) on outcomes in patients evaluated in an emergency department for chest pain. (acc.org)
  • Methods Thirty-five patients underwent 3D-perfusion CMR with data acquired at both end-systole and mid-diastole. (uzh.ch)
  • To investigate the effects of nifedipine on myocardial perfusion by MRI and on contractility by TDE, in patients with SSc. (eurekamag.com)
  • Myocardial SPECT perfusion imaging has been shown to provide important prognostic information in patients with known or suspected coronary artery disease. (pubmedcentralcanada.ca)
  • The study cohort consisted of 231 consecutive patients who underwent noncardiac surgery and had a preoperative dipyridamole thallium-201 imaging study. (onlinejacc.org)
  • Results of the prospective, multi-center U.S. study showed that Corus ® CAD , a blood-based gene expression test , demonstrated high accuracy with both a high negative predictive value (96 percent) and high sensitivity (89 percent) for assessing obstructive coronary artery disease (CAD) in a population of patients referred for stress testing with myocardial perfusion imaging (MPI). (cardiodx.com)
  • We studied 15 patients who underwent stress and rest N-13-labeled NH3 perfusion imaging on FR-PET and GC-PET systems. (sinapse.ac.uk)
  • however, in patients with a moderate-to-high risk for CAD, an imaging study is essential along with the stress test. (medscape.com)
  • The MRI perfusion index, determined from time-intensity curves, and systolic and diastolic strain rate determined by TDE were assessed at baseline, after a 72 hour vasodilator washout period, and after 14 days of oral treatment with nifedipine 60 mg/day. (eurekamag.com)
  • The use of vasodilator myocardial perfusion imaging in severe aortic stenosis: Is it time for a new prospective study? (springer.com)
  • In this issue of the journal, Hussain et al examined retrospectively the safety of vasodilator stress imaging in a population with severe aortic stenosis. (springer.com)
  • Current PET radiotracers such as rubidium-82 (half-life, 76 sec), oxygen-15 water (2 min) or nitrogen-13 ammonia (10 min) are labeled with radionuclides with very short half-lives, necessitating that stress imaging is performed under pharmacological vasodilator stress instead of exercise testing. (uni-wuerzburg.de)
  • van Dijk JD, Borren NM, Mouden M, van Dalen JA, Ottervanger JP, Jager PL. Effect of a patient-specific minimum activity in stress myocardial perfusion imaging using CZT-SPECT: prognostic value, radiation dose, and scan outcome. (springermedizin.de)
  • In the case of renal perfusion assessment, a renal blood flow scan can help find blockages or narrowing of blood flow to the kidneys. (reference.com)
  • A Myocardial Perfusion Scan images the blood supply (perfusion) to the heart muscle using a gamma camera. (lakeimaging.com.au)
  • A myocardial perfusion scan is a type of nuclear medicine imaging procedure. (trinitymedicalimaging.co.uk)
  • The myocardial perfusion scan evaluates the heart's function and blood flow. (trinitymedicalimaging.co.uk)
  • There are two types of stress myocardial perfusion scans, one that is used in conjunction with exercise (myocardial perfusion scan with exercise) and one that is used in conjunction with medication (pharmacologic myocardial perfusion scan). (trinitymedicalimaging.co.uk)
  • This allows imaging time to be reduced by half while maintaining the image quality of a standard MPI scan. (smartteleradiology.com)
  • Myocardial perfusion imaging , medical procedure that uses radioactive tracers, primarily thallium , to detect abnormalities in the blood supply to the heart muscle . (britannica.com)
  • More extensive perfusion abnormalities are associated with more severe CAD and a greater risk for important cardiac events. (snmjournals.org)
  • Thus, the early detection of myocardial perfusion abnormalities is si. (bioportfolio.com)
  • MPI tests were also evaluated separately by an independent expert panel, with quantification of the size of the perfusion abnormality and identification of nonperfusion abnormalities. (diabetesjournals.org)
  • Previous studies have suggested that dihydropyridine-type calcium channel blockers mitigate both myocardial perfusion and function abnormalities. (eurekamag.com)
  • During a 24 ± 13 month follow-up period, there were no deaths or myocardial infarctions, while an eleventh patient underwent revascularization 19 months after MPI. (biomedsearch.com)
  • We combine myocardial perfusion images with exercise (walking on a treadmill) to assess the blood flow to the heart muscle. (mountsinai.org)
  • Myocardial perfusion imaging (MPI), which is used to assess the sufficiency of myocardial blood flow, is an important tool in the diagnostics of coronary artery disease and in determining its severity. (healthcanal.com)
  • King MA, Dey J, Johnson K, Dasari P, Mukherjee JM, McNamara JE, Konik A, Lindsay C, Zheng S, Coughlin D. Use of MRI to assess the prediction of heart motion with gross body motion in myocardial perfusion imaging by stereotracking of markers on the body surface. (umassmed.edu)
  • Until today it was not possible to reliably assess the function of a new bypass, i.e., to measure myocardial perfusion. (bioportfolio.com)
  • We inject a small amount of an imaging agent Tc-99m sestamibi or Thallium, into the blood stream during rest and during exercise or chemical stress. (mountsinai.org)
  • Fractional extraction (Emax) for 99mTc sestamibi is lower than that for thallium 201, but net myocardial uptake is comparable between the two radionuclides. (biomedsearch.com)
  • Myocardial uptake is proportional to regional flow as found with 99mTc sestamibi and 201Tl. (biomedsearch.com)
  • Dipyridamole myocardial blood flow (MBF) was assessed using 99mTc-sestamibi by measuring first-transit counts in the pulmonary artery and myocardial count rate from G-SPECT images. (nih.gov)
  • Automated quantification of 99m Tc-sestamibi SPECT myocardial perfusion scans provides objective prognostic information and may complement the conventional visual image interpretation. (snmjournals.org)
  • These reports come from the center that developed the commercial package and used rest 201 Tl/exercise 99m Tc-sestamibi dual-isotope myocardial perfusion SPECT. (snmjournals.org)
  • Gholamrezanezhad A, Moinian D, Eftekhari M, Mirpour S, Hajimohammadi H. The prevalence and significance of increased gastric wall radiotracer uptake in sestamibi myocardial perfusion SPECT. (springer.com)
  • Effect of proton pump inhibitors and H2 antagonists on the stomach wall in 99mTc-sestamibi cardiac imaging. (springer.com)
  • An algorithm for conversion of 12-segment perfusion scores to 17-segment scores has been developed which is highly correlated to visual interpretation by the 17-segment model with nearly identical prognostic information. (pubmedcentralcanada.ca)
  • The goal of this study was to ( 1 ) demonstrate that a conversion algorithm from a 12-segement to a 17-segment model would be highly correlated with expert assessment of the images according to a 17-segment model and ( 2 ) to demonstrate that this conversion does not negatively effect the prognostic information that we have previously demonstrated from our 12-segment model data. (pubmedcentralcanada.ca)
  • Contrast materialâ€"enhanced myocardial perfusion imaging by using cardiac magnetic resonance (MR) imaging has, during the past decade, evolved into an accurate technique for diagnosing coronary artery disease, with excellent prognostic value. (thepreparedminds.com)
  • ASNC is dedicated to continuous quality improvement, education and patient-centered imaging, illustrating the ongoing commitment as a leader in the field of nuclear imaging and improving patient outcomes. (prweb.com)
  • 201Tl is widely used in nuclear medicine to carry out myocardial perfusion imaging (MPI). (irsn.fr)
  • The results were originally published in Nuclear Medicine Communications, International Journal of Molecular Imaging, and Annals of Nuclear Medicine. (healthcanal.com)
  • Multicenter evaluation of stress-first myocardial perfusion image triage by nuclear technologists and automated quantification. (umassmed.edu)
  • The images were retrieved, reviewed and re-processed by a 4th year Nuclear Medicine registrar to ensure they were rightly called. (wits.ac.za)
  • This work raises 2 interesting questions: do we need pixel-level resolution for mapping MBF, despite the prevalent use of simpler and robust methods, which are exemplified by the bull's-eye plot, well known from nuclear cardiac imaging? (onlinejacc.org)
  • Myocardial perfusion imaging, also referred to as the thallium stress test, is a type of nuclear scanning test similar to a routine exercise stress test but with images. (heart.org)
  • Currently, nuclear myocardial scans include both perfusion and gated wall motion images. (medscape.com)
  • In a Nuclear Perfusion Stress Test, pictures of heart circulation are obtained using an isotope that is injected intravenously. (windwardmedispa.com)
  • Myocardial Perfusion Imaging (MPI), also known as a Nuclear Stress Test, is done to determine how well the coronary arteries are delivering blood to your heart, as well as areas of the heart muscle that aren't getting enough blood flow. (myhealthcentre.ca)
  • This property of radiotracers gives nuclear medicine specialists the ability to image the extent of a disease process in the body based on the cellular function and physiology, rather than relying on physical changes in the tissue anatomy. (reliasmedia.com)
  • Nuclear medicine, in a sense, is radiology done inside out, or endo-radiology, because it images radiation emitted from within the body rather than radiation that is generated by external sources such as x-rays. (reliasmedia.com)
  • The greater, still unrealized value of these unique erythrocyte tracers, however, resides in their ability to depict the spatial distribution of myocardial perfusion and to quantify intramyocardial blood volume, properties that render UCAs ideal for the detection and localization of coronary artery disease (CAD). (onlinejacc.org)
  • Purpose: The aim of this study was to evaluate whether ECG-triggered coronary calcium scoring (CCS) scans can be used for attenuation correction (AC) to quantify myocardial blood flow (MBF) and coronary flow reserve (CFR) assessed by PET/CT with 13N-ammonia. (rero.ch)
  • Start Forskningsoutput Perfusion vector-a new method to quantify myocardial perfusi. (lu.se)
  • Then we use a scanning device (gamma camera) to measure the uptake of the imaging agent in the heart during stress and at rest. (mountsinai.org)
  • Exploratory analyses from this study showed high myocardial uptake that was stable over time with favorable myocardial to background ratios. (biospace.com)
  • Association of use of proton pump inhibitors and H2 antagonists with stomach wall uptake in (99m)Tc-methoxy-isobutyl-isonitrile (MIBI) myocardial perfusion imaging. (springer.com)
  • It enables immediate assessment of both the increase and spatial distribution of myocardial perfusion following declamping of an arterial graft. (spie.org)
  • Background and objective: The absolute quantification of dynamic myocardial perfusion (MP) PET imaging is challenged by the limited spatial resolution of individual frame images due to division of the data into shorter frames. (elsevier.com)
  • 1 ) in this issue of iJACC presents the results of a validation study on the use of cardiac magnetic resonance (CMR) imaging to map myocardial blood flow (MBF) at the spatial resolution of the underlying images ("pixel-wise"), acquired during the first pass of a gadolinium contrast bolus injection. (onlinejacc.org)
  • But, imaging with higher spatial resolution also generally entails more noise, and this equally applies to noise levels in MBF maps that are generated from images. (onlinejacc.org)
  • CT based myocardial blood flow (MBFCT), blood volume (MBVCT) and transit constant (Ktrans), as well as microsphere's based myocardial blood flow (MBFMic) were derived for each myocardial segment. (nih.gov)
  • Patient management after noninvasive cardiac imaging results from SPARC (Study of myocardial perfusion and coronary anatomy imaging roles in coronary artery disease). (harvard.edu)
  • Cardiac Imaging in the Diagnosis of Coronary Artery Disease. (semanticscholar.org)
  • Myocardial perfusion imaging is a test to look at the blood flow and function of the heart. (stdavids.com)
  • After short sections outlining the state of the art in the traditional applications of CT to image structure and function, the full range of CT techniques that may be employed to evaluate the myocardial blood supply are discussed in detail. (springer.com)
  • Recent advances in technology have resulted in the development of scanners that can image the heart blood vessels within 10 to 20 minutes but without the need for admission to hospital or insertion of catheters. (clinicaltrials.gov)
  • Myocardial perfusion imaging is a non-invasive imaging testing modality that shows how well the blood flows through (perfuses) your heart muscle. (mountsinai.org)
  • The imaging tests can show this decrease in blood flow. (mountsinai.org)
  • Myocardial perfusion studies can identify areas of your heart muscle that are not getting enough blood as well as the areas that are scarred from a heart attack. (mountsinai.org)
  • CT evaluation of the myocardial blood supply: Fast kV-switching dual-energy CT. (indigo.ca)
  • This technique measures myocardial perfusion during stress, and often at rest, after the injection of a small amount of a radiopharmaceutical that is extracted by myocardial cells in proportion to myocardial blood flow. (renalandurologynews.com)
  • Subsequent milestones included the development of second-generation UCAs capable of transpulmonary transit ( 1 ), placement of sophisticated UCA detection strategies on ultrasound imaging systems ( 4 ), and animal studies proving the principle that MCE can measure intramyocardial blood volume and hence detect CAD during stress testing ( 5,6 ). (onlinejacc.org)
  • Myocardial blood flow (MBF) was quantified in the 10 mid- and apical cardiac segments at rest and after stress. (bmj.com)
  • Myocardial scans give information useful in diagnosing and managing conditions such as coronary artery disease, dead tissue resulting from a lack of blood supply (infarcts) and diseases of the heart muscle (cardiomyopathy). (lakeimaging.com.au)
  • Transitory, subendocardial dark rim artifacts seen during CMR first-pass imaging are therefore effectively suppressed from the blood flow maps. (onlinejacc.org)
  • The high-blood myocardial contrast of SSFP allows automatic segmentation, which, combined with registration, facilitates image analysis. (biomedcentral.com)
  • serendipitously, this causes blood signal to remain almost constant, whereas the myocardial signal exhibits a nearly linear correlation with contrast agent concentration. (biomedcentral.com)
  • Myocardial perfusion imaging shows how well the heart muscle is supplied (perfused) with blood using a radioactive substance called thallium that's injected into the bloodstream when the patient is at maximum level of exercise. (heart.org)
  • Myocardial perfusion imaging uses a small amount of radioactive tracer to check the blood flow to your heart. (beaumont.org)
  • A Stress/Rest Myocardial Perfusion Imaging (MPI) Study is a type of stress test that uses PET or SPECT imaging of a patient's heart before and after exercise to determine the effect of physical stress on the flow of blood through the coronary arteries and the heart muscle. (cms-plus.com)
  • The three-dimensional images produced by this study are called perfusion images because they show which areas of the heart muscle are perfused, or supplied, with blood. (cms-plus.com)
  • Myocardial perfusion imaging (MPI) refers to the utilization of radiotracers to image regional myocardial perfusion from coronary artery blood flow to the heart muscle. (reliasmedia.com)
  • A decrease in the blood flow is detected by the images of MPI. (azheartdoctor.com)
  • A Myocardial Perfusion Imaging test (MPI) shows how well blood flows through or perfuses your heart. (mic.ca)
  • At MIC, our Myocardial Perfusion Imaging Test includes a measurement of ejection fraction or the amount of blood pumped out of the heart during each heartbeat (contraction). (mic.ca)
  • Myocardial perfusion imaging from the emergency department remains a vital component of the diagnosis or exclusion of coronary artery disease as the etiology of chest pain. (eurekaselect.com)
  • In addition, myocardial perfusion imaging should always be used as an adjunct when pharmacologic stress testing is performed. (medscape.com)
  • Bidaut, L.M. and Vallee, J.P. (2001) Automated registra- tion of dynamic MR images for the quantification of myocardial perfusion. (scirp.org)
  • The acquired images then are assessed to determine whether myocardial perfusion during stress is normal or abnormal, and if needed, whether there is any change in perfusion from stress to rest. (renalandurologynews.com)
  • Interpreting imaging stress tests requires experience and expertise, and not all institutions can excel in all modalities. (acpjc.org)