NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
Dilation of an occluded coronary artery (or arteries) by means of a balloon catheter to restore myocardial blood supply.
Use of infusions of FIBRINOLYTIC AGENTS to destroy or dissolve thrombi in blood vessels or bypass grafts.
Radiography of the vascular system of the heart muscle after injection of a contrast medium.
Elements of limited time intervals, contributing to particular results or situations.
MYOCARDIAL INFARCTION in which the anterior wall of the heart is involved. Anterior wall myocardial infarction is often caused by occlusion of the left anterior descending coronary artery. It can be categorized as anteroseptal or anterolateral wall myocardial infarction.
Generally, restoration of blood supply to heart tissue which is ischemic due to decrease in normal blood supply. The decrease may result from any source including atherosclerotic obstruction, narrowing of the artery, or surgical clamping. Reperfusion can be induced to treat ischemia. Methods include chemical dissolution of an occluding thrombus, administration of vasodilator drugs, angioplasty, catheterization, and artery bypass graft surgery. However, it is thought that reperfusion can itself further damage the ischemic tissue, causing MYOCARDIAL REPERFUSION INJURY.
An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.
The geometric and structural changes that the HEART VENTRICLES undergo, usually following MYOCARDIAL INFARCTION. It comprises expansion of the infarct and dilatation of the healthy ventricle segments. While most prevalent in the left ventricle, it can also occur in the right ventricle.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow.
The hospital unit in which patients with acute cardiac disorders receive intensive care.
The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.
Fibrinolysin or agents that convert plasminogen to FIBRINOLYSIN.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
Precordial pain at rest, which may precede a MYOCARDIAL INFARCTION.
In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.
Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting.
A family of percutaneous techniques that are used to manage CORONARY OCCLUSION, including standard balloon angioplasty (PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY), the placement of intracoronary STENTS, and atheroablative technologies (e.g., ATHERECTOMY; ENDARTERECTOMY; THROMBECTOMY; PERCUTANEOUS TRANSLUMINAL LASER ANGIOPLASTY). PTCA was the dominant form of PCI, before the widespread use of stenting.
The restoration of blood supply to the myocardium. (From Dorland, 28th ed)
Coagulation of blood in any of the CORONARY VESSELS. The presence of a blood clot (THROMBUS) often leads to MYOCARDIAL INFARCTION.
The return of a sign, symptom, or disease after a remission.
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.
The veins and arteries of the HEART.
Shock resulting from diminution of cardiac output in heart disease.
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
MYOCARDIAL INFARCTION in which the inferior wall of the heart is involved. It is often caused by occlusion of the right coronary artery.
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
A vital statistic measuring or recording the rate of death from any cause in hospitalized populations.
The circulation of blood through the CORONARY VESSELS of the HEART.
The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.
Disease having a short and relatively severe course.
Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.
Pressure, burning, or numbness in the chest.
Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
The hollow, muscular organ that maintains the circulation of the blood.
Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Statistical models used in survival analysis that assert that the effect of the study factors on the hazard rate in the study population is multiplicative and does not change over time.
The systems and processes involved in the establishment, support, management, and operation of registers, e.g., disease registers.
The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.
An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesized to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics.
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
A class of statistical procedures for estimating the survival function (function of time, starting with a population 100% well at a given time and providing the percentage of the population still well at later times). The survival analysis is then used for making inferences about the effects of treatments, prognostic factors, exposures, and other covariates on the function.
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Laceration or tearing of cardiac tissues appearing after MYOCARDIAL INFARCTION.
A set of techniques used when variation in several variables has to be studied simultaneously. In statistics, multivariate analysis is interpreted as any analytic method that allows simultaneous study of two or more dependent variables.
The confinement of a patient in a hospital.
Analyses for a specific enzyme activity, or of the level of a specific enzyme that is used to assess health and disease risk, for early detection of disease or disease prediction, diagnosis, and change in disease status.
Studies which start with the identification of persons with a disease of interest and a control (comparison, referent) group without the disease. The relationship of an attribute to the disease is examined by comparing diseased and non-diseased persons with regard to the frequency or levels of the attribute in each group.
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.
Bleeding or escape of blood from a vessel.
One of the three polypeptide chains that make up the TROPONIN complex. It is a cardiac-specific protein that binds to TROPOMYOSIN. It is released from damaged or injured heart muscle cells (MYOCYTES, CARDIAC). Defects in the gene encoding troponin T result in FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.
Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
One of the three polypeptide chains that make up the TROPONIN complex. It inhibits F-actin-myosin interactions.
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.
Statistical models which describe the relationship between a qualitative dependent variable (that is, one which can take only certain discrete values, such as the presence or absence of a disease) and an independent variable. A common application is in epidemiology for estimating an individual's risk (probability of a disease) as a function of a given risk factor.
The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.
An effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.
Formation and development of a thrombus or blood clot in the blood vessel.
Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
A nonparametric method of compiling LIFE TABLES or survival tables. It combines calculated probabilities of survival and estimates to allow for observations occurring beyond a measurement threshold, which are assumed to occur randomly. Time intervals are defined as ending each time an event occurs and are therefore unequal. (From Last, A Dictionary of Epidemiology, 1995)
Works about clinical trials that involve at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table.
A distribution in which a variable is distributed like the sum of the squares of any given independent random variable, each of which has a normal distribution with mean of zero and variance of one. The chi-square test is a statistical test based on comparison of a test statistic to a chi-square distribution. The oldest of these tests are used to detect whether two or more population distributions differ from one another.
Complete blockage of blood flow through one of the CORONARY ARTERIES, usually from CORONARY ATHEROSCLEROSIS.
Narrowing or constriction of a coronary artery.
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Services specifically designed, staffed, and equipped for the emergency care of patients.
A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image.
Insufficiency of arterial or venous blood supply to the spleen due to emboli, thrombi, vascular torsion, or pressure that produces a macroscopic area of necrosis. (From Stedman, 25th ed)
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances.
A highly acidic mucopolysaccharide formed of equal parts of sulfated D-glucosamine and D-glucuronic acid with sulfaminic bridges. The molecular weight ranges from six to twenty thousand. Heparin occurs in and is obtained from liver, lung, mast cells, etc., of vertebrates. Its function is unknown, but it is used to prevent blood clotting in vivo and vitro, in the form of many different salts.
Agents that prevent clotting.
Conditions or pathological processes associated with the disease of diabetes mellitus. Due to the impaired control of BLOOD GLUCOSE level in diabetic patients, pathological processes develop in numerous tissues and organs including the EYE, the KIDNEY, the BLOOD VESSELS, and the NERVE TISSUE.
Contractile activity of the MYOCARDIUM.
An isoenzyme of creatine kinase found in the CARDIAC MUSCLE.
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.
Disease-related laceration or tearing of tissues of the heart, including the free-wall MYOCARDIUM; HEART SEPTUM; PAPILLARY MUSCLES; CHORDAE TENDINEAE; and any of the HEART VALVES. Pathological rupture usually results from myocardial infarction (HEART RUPTURE, POST-INFARCTION).
Striated muscle cells found in the heart. They are derived from cardiac myoblasts (MYOBLASTS, CARDIAC).
Controlled physical activity which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used.
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Examinations used to diagnose and treat heart conditions.
A type of imaging technique used primarily in the field of cardiology. By coordinating the fast gradient-echo MRI sequence with retrospective ECG-gating, numerous short time frames evenly spaced in the cardiac cycle are produced. These images are laced together in a cinematic display so that wall motion of the ventricles, valve motion, and blood flow patterns in the heart and great vessels can be visualized.
Surgical removal of an obstructing clot or foreign material from a blood vessel at the point of its formation. Removal of a clot arising from a distant site is called EMBOLECTOMY.
Pathological conditions involving the HEART including its structural and functional abnormalities.
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
Procedures for finding the mathematical function which best describes the relationship between a dependent variable and one or more independent variables. In linear regression (see LINEAR MODELS) the relationship is constrained to be a straight line and LEAST-SQUARES ANALYSIS is used to determine the best fit. In logistic regression (see LOGISTIC MODELS) the dependent variable is qualitative rather than continuously variable and LIKELIHOOD FUNCTIONS are used to find the best relationship. In multiple regression, the dependent variable is considered to depend on more than a single independent variable.
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Abnormal fluid retention by the body due to impaired cardiac function or heart failure. It is usually characterized by increase in venous and capillary pressure, and swollen legs when standing. It is different from the generalized edema caused by renal dysfunction (NEPHROTIC SYNDROME).
The span of viability of a tissue or an organ.
Therapy with two or more separate preparations given for a combined effect.
Infarctions that occur in the BRAIN STEM which is comprised of the MIDBRAIN; PONS; and MEDULLA OBLONGATA. There are several named syndromes characterized by their distinctive clinical manifestations and specific sites of ischemic injury.
Laceration or tearing of the VENTRICULAR SEPTUM, usually caused by MYOCARDIAL INFARCTION.
The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.
The number of times the HEART VENTRICLES contract per unit of time, usually per minute.
An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an activator that converts plasminogen to plasmin, thereby initiating fibrinolysis. Its half-life is about 90 minutes compared to 5 minutes for TPA; (TISSUE PLASMINOGEN ACTIVATOR); 16 minutes for UROKINASE-TYPE PLASMINOGEN ACTIVATOR and 23 minutes for STREPTOKINASE. If treatment is initiated within 3 hours of onset of symptoms for acute myocardial infarction, the drug preserves myocardial tissue and left ventricular function and increases coronary artery patency. Bleeding complications are similar to other thrombolytic agents.
One of the minor protein components of skeletal muscle. Its function is to serve as the calcium-binding component in the troponin-tropomyosin B-actin-myosin complex by conferring calcium sensitivity to the cross-linked actin and myosin filaments.
Markedly reduced or absent REPERFUSION in an infarct zone following the removal of an obstruction or constriction of an artery.
Recurrent narrowing or constriction of a coronary artery following surgical procedures performed to alleviate a prior obstruction.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
Substances used to allow enhanced visualization of tissues.
Counterpulsation in which a pumping unit synchronized with the patient's electrocardiogram rapidly fills a balloon in the aorta with helium or carbon dioxide in early diastole and evacuates the balloon at the onset of systole. As the balloon inflates, it raises aortic diastolic pressure, and as it deflates, it lowers aortic systolic pressure. The result is a decrease in left ventricular work and increased myocardial and peripheral perfusion.
Interfacility or intrahospital transfer of patients. Intrahospital transfer is usually to obtain a specific kind of care and interfacility transfer is usually for economic reasons as well as for the type of care provided.
Method in which prolonged electrocardiographic recordings are made on a portable tape recorder (Holter-type system) or solid-state device ("real-time" system), while the patient undergoes normal daily activities. It is useful in the diagnosis and management of intermittent cardiac arrhythmias and transient myocardial ischemia.
A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack.
A radionuclide imaging agent used primarily in scintigraphy or tomography of the heart to evaluate the extent of the necrotic myocardial process. It has also been used in noninvasive tests for the distribution of organ involvement in different types of amyloidosis and for the evaluation of muscle necrosis in the extremities.
Reconstruction or repair of a blood vessel, which includes the widening of a pathological narrowing of an artery or vein by the removal of atheromatous plaque material and/or the endothelial lining as well, or by dilatation (BALLOON ANGIOPLASTY) to compress an ATHEROMA. Except for ENDARTERECTOMY, usually these procedures are performed via catheterization as minimally invasive ENDOVASCULAR PROCEDURES.
The hospital department responsible for the administration and provision of diagnostic and therapeutic services for the cardiac patient.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
Conveying ill or injured individuals from one place to another.
The interval of time between onset of symptoms and receiving therapy.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
A catecholamine derivative with specificity for BETA-1 ADRENERGIC RECEPTORS. It is commonly used as a cardiotonic agent after CARDIAC SURGERY and during DOBUTAMINE STRESS ECHOCARDIOGRAPHY.
Low-molecular-weight fragment of heparin, having a 4-enopyranosuronate sodium structure at the non-reducing end of the chain. It is prepared by depolymerization of the benzylic ester of porcine mucosal heparin. Therapeutically, it is used as an antithrombotic agent. (From Merck Index, 11th ed)
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
Spasm of the large- or medium-sized coronary arteries.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
The process of accepting patients. The concept includes patients accepted for medical and nursing care in a hospital or other health care institution.
A plasma protein that circulates in increased amounts during inflammation and after tissue damage.
Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.
A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.
A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain.
Tomography using x-ray transmission and a computer algorithm to reconstruct the image.
Inhaling and exhaling the smoke of burning TOBACCO.
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
A PEPTIDE that is secreted by the BRAIN and the HEART ATRIA, stored mainly in cardiac ventricular MYOCARDIUM. It can cause NATRIURESIS; DIURESIS; VASODILATION; and inhibits secretion of RENIN and ALDOSTERONE. It improves heart function. It contains 32 AMINO ACIDS.
A graphic means for assessing the ability of a screening test to discriminate between healthy and diseased persons; may also be used in other studies, e.g., distinguishing stimuli responses as to a faint stimuli or nonstimuli.
VASCULAR DISEASES that are associated with DIABETES MELLITUS.
The removal of secretions, gas or fluid from hollow or tubular organs or cavities by means of a tube and a device that acts on negative pressure.
Situations or conditions requiring immediate intervention to avoid serious adverse results.
The study of the heart, its physiology, and its functions.
The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)
Imaging of a ventricle of the heart after the injection of a radioactive contrast medium. The technique is less invasive than cardiac catheterization and is used to assess ventricular function.
Application of a ligature to tie a vessel or strangulate a part.
A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
The period of confinement of a patient to a hospital or other health facility.
The degree to which BLOOD VESSELS are not blocked or obstructed.
A partial or complete return to the normal or proper physiologic activity of an organ or part following disease or trauma.
The administrative process of discharging the patient, alive or dead, from hospitals or other health facilities.
Exposure of myocardial tissue to brief, repeated periods of vascular occlusion in order to render the myocardium resistant to the deleterious effects of ISCHEMIA or REPERFUSION. The period of pre-exposure and the number of times the tissue is exposed to ischemia and reperfusion vary, the average being 3 to 5 minutes.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
Maintenance of blood flow to an organ despite obstruction of a principal vessel. Blood flow is maintained through small vessels.
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Conditional probability of exposure to a treatment given observed covariates.
Motion pictures of the passage of contrast medium through blood vessels.
The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level.
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
The use of ultrasound to guide minimally invasive surgical procedures such as needle ASPIRATION BIOPSY; DRAINAGE; etc. Its widest application is intravascular ultrasound imaging but it is useful also in urology and intra-abdominal conditions.
Period of contraction of the HEART, especially of the HEART VENTRICLES.
The circulation of the BLOOD through the MICROVASCULAR NETWORK.
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see PENTETIC ACID), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Recording of the moment-to-moment electromotive forces of the heart on a plane of the body surface delineated as a vector function of time.
Transfer of MESENCHYMAL STEM CELLS between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS).
A vehicle equipped for transporting patients in need of emergency care.
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
A conjugated protein which is the oxygen-transporting pigment of muscle. It is made up of one globin polypeptide chain and one heme group.
The prevention of recurrences or exacerbations of a disease or complications of its therapy.
The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process.
Use of HIRUDINS as an anticoagulant in the treatment of cardiological and hematological disorders.
Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.

Site of myocardial infarction. A determinant of the cardiovascular changes induced in the cat by coronary occlusion. (1/19124)

The influence of site of acute myocardial infarction on heart rate, blood pressure, cardiac output, total peripheral resistance (TPR), cardiac rhythm, and mortality was determined in 58 anesthetized cats by occlusion of either the left anterior descending (LAD), left circumflex or right coronary artery. LAD occlusion resulted in immediate decrease in cardiac output, heart rate, and blood pressure, an increase in TPR, and cardiac rhythm changes including premature ventricular beats, ventricular tachycardia, and occasionally ventricular fibrillation. The decrease in cardiac output and increase in TPR persisted in the cats surviving a ventricular arrhythmia. In contrast, right coronary occlusion resulted in a considerably smaller decrease in cardiac output. TPR did not increase, atrioventricular condition disturbances were common, and sinus bradycardia and hypotension persisted in the cats recovering from an arrhythmia. Left circumflex ligation resulted in cardiovascular changes intermediate between those produced by occlusion of the LAD or the right coronary artery. Mortality was similar in each of the three groups. We studied the coronary artery anatomy in 12 cats. In 10, the blood supply to the sinus node was from the right coronary artery and in 2, from the left circumflex coronary artery. The atrioventricular node artery arose from the right in 9 cats, and from the left circumflex in 3. The right coronary artery was dominant in 9 cats and the left in 3. In conclusion, the site of experimental coronary occlusion in cats is a major determinant of the hemodynamic and cardiac rhythm changes occurring after acute myocardial infarction. The cardiovascular responses evoked by ligation are related in part to the anatomical distribution of the occluded artery.  (+info)

Hierarchy of ventricular pacemakers. (2/19124)

To characterize the pattern of pacemaker dominance in the ventricular specialized conduction system (VSCS), escape ventricular pacemakers were localized and quantified in vivo and in virto, in normal hearts and in hearts 24 hours after myocardial infarction. Excape pacemaker foci were localized in vivo during vagally induced atrial arrest by means of electrograms recorded from the His bundle and proximal bundle branches and standard electrocardiographic limb leads. The VSCS was isolated using a modified Elizari preparation or preparations of each bundle branch. Peacemakers were located by extra- and intracellular recordings. Escape pacemaker foci in vivo were always in the proximal conduction system, usually the left bundle branch. The rate was 43+/-11 (mean+/-SD) beats/min. After beta-adrenergic blockade, the mean rate fell to 31+/-10 beats/min, but there were no shifts in pacemaker location. In the infarcted hearts, pacemakers were located in the peripheral left bundle branch. The mean rate was 146+/-20 beats/min. In isolated normal preparations, the dominant pacemakers usually were in the His bundle, firing at a mean rate of 43+/-10 beats/min. The rates of pacemakers diminished with distal progression. In infarcted hearts, the pacemakers invariably were in the infarct zone. The mean firing rates were not influenced by beta-adrenergic blockade. The results indicate that the dominant pacemakers are normally in the very proximal VSCS, but after myocardial infarction pacemaker dominance is shifted into the infarct. Distribution of pacemaker dominance is independent of sympathetic influence.  (+info)

Anti-heart autoantibodies in ischaemic heart disease patients. (3/19124)

One hundred and ninety-nine ischaemic heart disease (IHD) patients were studied with regard to the prevalence of anti-heart autoantibodies (AHA). The incidence of AHA in IHD patients was 1%: one out of 102 patients who suffered acute myocardial infarction (AMI), one out of seventy-two patients who suffered from acute coronary insufficiency (ACI), and none out of twenty-five patients with other signs and symptoms of IHD, had AHA in their sera. An additional 2% of patients who suffered from AMI developed detectable antibody levels during a follow-up period of 15 days. In comparison,, 53% of patients (eight out of fifteen) who underwent heart surgery and who had no AHA prior to operation, developed these antibodies in their sera during 1-2 weeks following operation.  (+info)

Is hospital care involved in inequalities in coronary heart disease mortality? Results from the French WHO-MONICA Project in men aged 30-64. (4/19124)

OBJECTIVES: The goal of the study was to assess whether possible disparities in coronary heart disease (CHD) management between occupational categories (OC) in men might be observed and contribute to the increasing inequalities in CHD morbidity and mortality reported in France. METHODS: The data from the three registers of the French MONICA Collaborative Centres (MCC-Lille, MCC-Strasbourg, and MCC-Toulouse) were analysed during two period: 1985-87 and 1989-91. Acute myocardial infarctions and coronary deaths concerning men, aged 30-64 years, were included. Non-professionally active and retired men were excluded. Results were adjusted for age and MCC, using a logistic regression analysis. RESULTS: 605 and 695 events were analysed for 1985-87 and 1989-91, respectively. Out of hospital cardiac arrests, with or without cardiac resuscitation, and 28 day case fatality rates were lower among upper executives in both periods. A coronarography before the acute event had been performed more frequently in men of this category and the proportion of events that could be hospitalised was higher among them. In both periods, the management of acute myocardial infarctions in hospital and prescriptions on discharge were similar among occupational categories. CONCLUSIONS: For patients who could be admitted to hospital, the management was found to be similar among OCs, as was the 28 day case fatality rate among the hospitalised patients. In contrast, lower prognosis and higher probability of being hospitalised after the event among some categories suggest that pre-hospital care and the patient's conditions before the event are the primary factors involved.  (+info)

Optimal thrombolytic strategies for acute myocardial infarction--bolus administration. (5/19124)

Optimal strategies for thrombolysis in myocardial infarction (TIMI) are still being sought because the TIMI 3 flow rates achievable using standard regimens average approximately 60%. Double bolus administration of recombinant tissue plasminogen activator (tPA) is a novel approach with potential for earlier patency combined with ease of administration. We reviewed total patency rates, TIMI 3 patency rates, mortality, stroke and intracranial haemorrhage rates in the major trials of accelerated infusion tPA/bolus tPA/reteplase in acute myocardial infarction. A direct comparison was performed with results of two recent trials of double bolus (two 50 mg boli, 30 min apart) vs. accelerated infusion tPA: the Double Bolus Lytic Efficacy Trial (DBLE), an angiographic study, and the COBALT Trial, a mortality study. The DBLE trial showed equivalent patency rates for accelerated infusion and double bolus administration of tPA. Reviewing other angiographic trials, total patency and TIMI 3 patency rates achievable with double bolus tPA were comparable to those with accelerated infusion tPA or bolus reteplase administration. The COBALT study demonstrated a 30-day mortality of 7.53% in patients treated with accelerated infusion tPA compared with 7.98% for double bolus tPA treated patients. The small excess in mortality with double bolus treatment was confined to the elderly; in those < or = 75 years, mortality rates were 5.6% and 5.7%, for double bolus and accelerated infusion, respectively, and rates for death or non-fatal stroke were 6.35% and 6.3%, respectively. Comparison with other trials demonstrated mortality, stroke and intracranial haemorrhage rates with double bolus treatment similar to those associated with either accelerated infusion tPA or bolus reteplase treatment. Double bolus administration of tPA to patients with acute myocardial infarction is associated with total patency, TIMI 3 patency, mortality, stroke and intracranial haemorrhage rates similar to those associated with either accelerated infusion of tPA or bolus reteplase.  (+info)

Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus. (6/19124)

OBJECTIVE: To determine rates of morbidity due to cardiovascular and cerebrovascular diseases among women with systemic lupus erythematosus (SLE). METHODS: I used the California Hospital Discharge Database, which contains information on all discharges from acute care hospitals in California, to identify women with SLE who had been hospitalized for treatment of either acute myocardial infarction (AMI), congestive heart failure (CHF), or cerebrovascular accident (CVA) from 1991 to 1994. I compared the proportions of hospitalizations for each cause among women with SLE with those in a group of women without SLE, for 3 age strata (18-44 years, 45-64 years, and > or =65 years). RESULTS: Compared with young women without SLE, young women with SLE were 2.27 times more likely to be hospitalized because of AMI (95% confidence interval [95% CI] 1.08-3.46), 3.80 times more likely to be hospitalized because of CHF (95% CI 2.41-5.19), and 2.05 times more likely to be hospitalized because of CVA (95% CI 1.17-2.93). Among middle-aged women with SLE, the frequencies of hospitalization for AMI and CVA did not differ from those of the comparison group, but the risk of hospitalization for CHF was higher (odds ratio [OR] 1.39, 95% CI 1.05-1.73). Among elderly women with SLE, the risk of hospitalization for AMI was significantly lower (OR 0.70, 95% CI 0.51-0.89), the risk of hospitalization for CHF was higher (OR 1.25, 95% CI 1.01-1.49), and the risk of hospitalization for CVA was not significantly different from those in the comparison group. CONCLUSION: Young women with SLE are at substantially increased risk of AMI, CHF, and CVA. The relative odds of these conditions decrease with age among women with SLE.  (+info)

Expression of skeletal muscle sarcoplasmic reticulum calcium-ATPase is reduced in rats with postinfarction heart failure. (7/19124)

OBJECTIVE: To determine whether heart failure in rats is associated with altered expression of the skeletal muscle sarcoplasmic reticulum Ca2+-ATPase (SERCA). METHODS: SERCA protein and mRNA were examined in the soleus muscles of eight female rats with heart failure induced by coronary artery ligation, six weeks after the procedure (mean (SEM) left ventricular end diastolic pressure 20.4 (2.2) mm Hg) and in six sham operated controls by western and northern analyses, respectively. RESULTS: SERCA-2a isoform protein was reduced by 16% (112 000 (4000) v 134 000 (2000) arbitrary units, p < 0.001), and SERCA-2a messenger RNA was reduced by 59% (0.24 (0. 06) v 0.58 (0.02) arbitrary units, p < 0.001). Although rats with heart failure had smaller muscles (0.54 mg/g v 0.66 mg/g body weight), no difference in locomotor activity was observed. CONCLUSIONS: These results may explain the previously documented abnormalities in calcium handling in skeletal muscle from animals with the same model of congestive heart failure, and could be responsible for the accelerated muscle fatigue characteristic of patients with heart failure.  (+info)

Recurring myocardial infarction in a 35 year old woman. (8/19124)

A 35 year old woman presented with acute myocardial infarction without any of the usual risk factors: she had never smoked; she had normal blood pressure; she did not have diabetes; plasma concentrations of total cholesterol and high and low density lipoprotein cholesterol, fibrinogen, homocysteine, and Lp(a) lipoprotein were normal. She was not taking oral contraceptives or any other medication. Coronary angiography showed occlusion of the left anterior descending coronary artery but no evidence of arteriosclerosis. Medical history disclosed a previous leg vein thrombosis with pulmonary embolism. Coagulation analysis revealed protein C deficiency. The recognition of protein C deficiency as a risk factor for myocardial infarction is important as anticoagulation prevents further thrombotic events, whereas inhibitors of platelet aggregation are ineffective.  (+info)

Indian Journal of Basic and Applied Medical Research; December 2013: Vol.-3, Issue-1 , 80-87 Original article : Effect of acute myocardial infarction on serum zinc level * DR. PRAVIN P. SHEKOKAR 1, DR. MRS. S. D. KAUNDINYA2 1Assistant Professor, Department of Physiology, Government Medical College, Akola, Collector Office Road, Akola. Pin 444001 (Maharashtra), India 2Professor & Head of Dept, Department of Physiology, Grant Government Medical College And Sir J.J. Hospital, Mumbai-8, India *Corrersponding author : Email: [email protected] Abstract: Introduction: Myocardial infarction is a common presentation of coronary artery disease. The diagnosis of acute myocardial infarction (AMI) is of vital importance from the management and prognosis point of view. Objective: The purpose of this study was to investigate serum zinc level in acute myocardial infarction patients and to correlate it with biochemical parameter SGOT. Methods: In the present study 30 patients suffering from acute myocardial ...
BACKGROUND: The Thrombolysis In Myocardial Infarction (TIMI) Risk Score has been shown to predict prognosis in acute coronary syndromes (ACS) comprised of unstable angina (UA) and non-ST segment elevation myocardial infarction (STEMI). We sought to evaluate the impact of newer antiplatelet and antithrombotic therapies for ACS, such as glycoprotein IIb/IIIa inhibitors (GPI) and low molecular weight heparin (LMWH), on in-hospital outcomes over time in patients (pts) with similar TIMI risk scores.. METHODS: The baseline demographics and clinical outcomes of pts with ACS (UA and non-STEMI) in 1998 (Group 1998) and 2000 (Group 2000) at a single large university medical center were compared using a prospectively collected database. In-hospital major adverse cardiac events (MACE) included death, MI, or recurrent angina that resulted in urgent revascularization. Risk was estimated by utilizing the TIMI Risk Score, which uses 7 predictor variables: age , 65 years, at least 3 risk factors for coronary ...
TY - JOUR. T1 - Non-ST-segment-elevation myocardial infarction among patients with chronic kidney disease. T2 - A propensity score-matched comparison of percutaneous coronary intervention versus conservative management. AU - Bhatia, Subir. AU - Arora, Shilpkumar. AU - Bhatia, Sravya M.. AU - Al-Hijji, Mohammed. AU - Reddy, Yogesh N.V.. AU - Patel, Parshva. AU - Rihal, Charanjit S.. AU - Gersh, Bernard J.. AU - Deshmukh, Abhishek. N1 - Publisher Copyright: © 2018 The Authors.. PY - 2018/3/20. Y1 - 2018/3/20. N2 - Background--Chronic kidney disease (CKD) remains an independent predictor of cardiovascular morbidity and mortality. CKD complicates referral for percutaneous coronary intervention (PCI) in non-ST-segment-elevation myocardial infarction (NSTEMI) patients because of the risk for acute kidney injury and the need for dialysis, with American College of Cardiology/American Heart Association guidelines underscoring the limited data on these patients. Methods and Results--Using the National ...
TY - JOUR. T1 - Subarachnoid hemorrhage simulating myocardial infarction. AU - De Marchena, Eduardo. AU - Pittaluga, Juan M.. AU - Ferreira, Alexandre C.. AU - Lowery, Maureen. AU - Romanelli, Renzo. AU - Morales, Azorides. PY - 1996/2/1. Y1 - 1996/2/1. N2 - We describe a patient with a subarachnoid hemorrhage that presented with electrocardiographic evidence of transmural myocardial infarction. The patient was found to have normal coronaries and on autopsy revealed generalized myocytolysis with no evidence of transmural myocardial infarction. This case illustrates the value of acute coronary angiography in patients with altered mental status and suspected myocardial infarction.. AB - We describe a patient with a subarachnoid hemorrhage that presented with electrocardiographic evidence of transmural myocardial infarction. The patient was found to have normal coronaries and on autopsy revealed generalized myocytolysis with no evidence of transmural myocardial infarction. This case illustrates the ...
TY - JOUR. T1 - Diabetes Mellitus and Cardiogenic Shock Complicating Acute Myocardial Infarction. AU - Echouffo Tcheugui, Justin. AU - Kolte, Dhaval. AU - Khera, Sahil. AU - Aronow, Herbert D.. AU - Abbott, J. Dawn. AU - Bhatt, Deepak L.. AU - Fonarow, Gregg C.. PY - 2018/7/1. Y1 - 2018/7/1. N2 - Background: Diabetes mellitus (diabetes) increases the risk of acute myocardial infarction, which can result in cardiogenic shock. Data on the relation of diabetes and the occurrence and prognosis of cardiogenic shock postacute myocardial infarction are scant. Methods: Among the National Inpatient Sample patients aged ≥18 years and hospitalized for acute myocardial infarction during the 2012-2014 period, we examined the association between diabetes and the incidence and outcomes of cardiogenic shock complicating acute myocardial infarction, using multivariable logistic and linear regression models. Results: Of 1,332,530 hospitalizations for acute myocardial infarction, 72,765 (5.5%) were complicated ...
TY - JOUR. T1 - Re. T2 - The Spillover Influence of Partners Education on Myocardial Infarction Incidence and Survival Respond. AU - Kilpi, Fanny. AU - Martikainen, Pekka. AU - Konttinen, Hanna. AU - Silventoinen, Karri. AU - Torssander, Jenny. AU - Kawachi, Ichiro. PY - 2018/7. Y1 - 2018/7. KW - DISEASE. KW - 3142 Public health care science, environmental and occupational health. U2 - 10.1097/EDE.0000000000000831. DO - 10.1097/EDE.0000000000000831. M3 - Letter. VL - 29. SP - E37-E37. JO - Epidemiology. JF - Epidemiology. SN - 1044-3983. IS - 4. ER - ...
Background: Chronic kidney disease (CKD) is a strong risk factor for cardiovascular events, and there are consistence evidences about worse short- and long-term outcomes in CKD patients with acute myocardial infarction. The aim of this study was to evaluate the effects and safety of triple antiplatelet therapy (aspirin plus clopidogrel plus cilostazol) in CKD patients with ST-elevation myocardial infarction (STEMI) compared with dual antiplatelet therapy (aspirin plus clopidogrel).. Methods and results: Among over 21,000 patients in Korean Acute Myocardial Infarction Registry (KAMIR) data, 5,138 STEMI patients who underwent successful primary percutaneous coronary intervention with drug-eluting stents were enrolled in this study. They were divided by estimated creatinine clearance (eCrCl); ≥ 60 ml/min (n=3,445; dual = 2169, triple = 1276) and , 60 ml/min (n=1693; dual = 1120, triple = 573). Various major adverse cardiac events including major bleeding at 12 months were evaluated. The triple ...
TY - JOUR. T1 - Comparison of delay times between Symptom onset of an acute ST-elevation myocardial infarction and hospital arrival in men and women ,65 years versus ≥65 years of age. T2 - Findings from the multicenter Munich Examination of Delay in Patients Experiencing Acute Myocardial Infarction (MEDEA) study. AU - Ladwig, Karl-Heinz. AU - Fang, Xiaoyan. AU - Wolf, Kathrin. AU - Hoschar, Sophia. AU - Albarqouni, Loai. AU - Ronel, Joram. AU - Meinertz, Thomas. AU - Spieler, Derek. AU - Laugwitz, Karl-Ludwig. AU - Schunkert, Heribert. N1 - Copyright © 2017 Elsevier Inc. All rights reserved.. PY - 2017/12/15. Y1 - 2017/12/15. N2 - Early administration of reperfusion therapy in acute ST-elevation myocardial infarctions (STEMI) is crucial to reduce mortality. Although female sex and old age are key factors contributing to an inadequate long prehospital delay time, little is known whether women ≥65 years are a particular risk population. Hence, we studied the interaction of sex and age (,65 ...
TY - JOUR. T1 - Sonothrombolysis in ST-Segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. AU - MRUSMI Investigators. AU - Mathias, Wilson. AU - Tsutsui, Jeane M.. AU - Tavares, Bruno G.. AU - Fava, Agostina M.. AU - Aguiar, Miguel O.D.. AU - Borges, Bruno C.. AU - Oliveira, Mucio T.. AU - Soeiro, Alexandre. AU - Nicolau, Jose C.. AU - Ribeiro, Henrique B.. AU - Chiang, Hsu Po. AU - Sbano, João C.N.. AU - Morad, Abdulrahman. AU - Goldsweig, Andrew. AU - Rochitte, Carlos E.. AU - Lopes, Bernardo B.C.. AU - Ramirez, José A.F.. AU - Kalil Filho, Roberto. AU - Porter, Thomas R.. PY - 2019/6/11. Y1 - 2019/6/11. N2 - Background: Preclinical studies have demonstrated that high mechanical index (MI)impulses from a diagnostic ultrasound transducer during an intravenous microbubble infusion (sonothrombolysis)can restore epicardial and microvascular flow in acute ST-segment elevation myocardial infarction (STEMI). Objectives: This study tested the clinical ...
I read the article by Yang JH,et al with great interest, in which the authors compared 1-year prognostic impacts of angiotensin receptor blockers (ARBs) with angiotensin converting enzyme inhibitors (ACEIs) in patients with ST segment elevation myocardial infarction (STEMI) with preserved left ventricular systolic function who underwent primary percutaneous coronary intervention (PCI) [1]. I believe it would be appreciated if authors discuss the long-term survival benefit of ARBs before concluding that ARBs are as beneficial as ACEIs in STEMI patients with preserved left ventricular systolic function after PCI.. Although ARBs could be an alternative to ACEIs, a recent observational study using inverse probability of treatment weighting and propensity score matching methods revealed that patients treated with ACEIs had significantly lower long-term mortality compared with those treated with ARBs from 2 to 5 years after acute myocardial infarction [2]. This study also demonstrated that crude ...
According to data from randomized, controlled trials, primary percutaneous coronary intervention (PCI) is the treatment of choice for ST-segment elevation myocardial infarction (MI). In these trials, 1 life was saved and 2 other life-threatening complications, including stroke and reinfarction, were prevented for every 50 patients with ST-segment elevation MI treated with primary PCI rather than thrombolytic therapy. Only 1 major bleeding episode occurred.. How can these superior results be realized outside the context of randomized trials? We anticipate 4 obstacles to instituting primary PCI as the universal treatment of ST-segment elevation MI: 1) lack of timely availability, 2) technical expertise of center and operator, 3) the need to address patient subgroups that are not studied in randomized trials, and 4) comparisons of primary PCI to newer pharmacologic regimens.. We propose 3 strategies to increase the availability of this procedure: 1) perform primary PCI in qualified community ...
TY - JOUR. T1 - Atrial fibrillation and risk of ST-segment-elevation versus non-ST-segment-elevation myocardial infarction the Atherosclerosis Risk in Communities (ARIC) study. AU - Soliman, Elsayed Z.. AU - Lopez, Faye. AU - ONeal, Wesley T.. AU - Chen, Lin Y.. AU - Bengtson, Lindsay. AU - Zhang, Zhu Ming. AU - Loehr, Laura. AU - Cushman, Mary. AU - Alonso, Alvaro. PY - 2015/5/26. Y1 - 2015/5/26. N2 - Background-It has recently been reported that atrial fibrillation (AF) is associated with an increased risk of myocardial infarction (MI). However, the mechanism underlying this association is currently unknown. Further study of the relationship of AF with the type of MI (ST-segment-elevation MI [STEMI] versus non-ST-segment-elevation MI [NSTEMI]) might shed light on the potential mechanisms. Methods and Results-We examined the association between AF and incident MI in 14 462 participants (mean age, 54 years; 56% women; 26% blacks) from the Atherosclerosis Risk in Communities (ARIC) study who ...
List of Tables. Table 1: Clinical subtypes of Indication. Table 2: Risk Factors. Table 3: Prevalence cases (%) Region wise. Table 4: Sources used for forecasting the data. Table 5: Myocardial Infarction Global Epidemiology, (2013-2023). Table 6: Prevalent Cases of Myocardial Infarction (Ages =XX Years), US (2013-2023). Table 7: Prevalent Cases of Myocardial Infarction By Sex (Males & Females), US (2013-2023). Table 8: Prevalent Cases By Myocardial Infarction Sub-population, US (2013-2023). Table 9: Prevalent Cases of Myocardial Infarction (Ages =XX Years), United Kingdom (2013-2023). Table 10: Prevalent Cases of Myocardial Infarction By Sex (Males & Females), United Kingdom (2013-2023). Table 11: Prevalent Cases By Myocardial Infarction Sub-population, United Kingdom (2013-2023). Table 12: Prevalent Cases of Myocardial Infarction (Ages =XX Years), Germany (2013-2023). Table 13: Prevalent Cases of Myocardial Infarction By Sex (Males & Females), Germany (2013-2023). Table 14: Prevalent Cases By ...
TY - JOUR. T1 - Comparison of outcomes of patients with painless versus painful ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention. AU - Cho, Jae Yeong. AU - Jeong, Myung Ho. AU - Ahn, Young Keun. AU - Kim, Jong Hyun. AU - Chae, Shung Chull. AU - Kim, Young Jo. AU - Hur, Seung Ho. AU - Seong, In Whan. AU - Hong, Taek Jong. AU - Choi, Dong Hoon. AU - Cho, Myeong Chan. AU - Kim, Chong Jin. AU - Seung, Ki Bae. AU - Chung, Wook Sung. AU - Jang, Yang Soo. AU - Cho, Seung Yun. AU - Rha, Seung Woon. AU - Bae, Jang Ho. AU - Cho, Jeong Gwan. AU - Park, Seung Jung. PY - 2012/2/1. Y1 - 2012/2/1. N2 - There are few data available on the prognosis of painless ST-segment elevation myocardial infarction (STEMI). The aim of this study was to determine the incidence, clinical characteristics, and outcomes of painless STEMI. We analyzed the Korea Acute Myocardial Infarction Registry (KAMIR) study, which enrolled 7,288 patients with STEMI (61.8 ± 12.8 years old, 74% men; ...
Aims. The TRA·CER trial compared vorapaxar, a novel platelet protease-activated receptor (PAR)-1 antagonist, with placebo in 12 944 patients with high-risk non-ST-segment elevation acute coronary syndromes (NSTE ACS). In this analysis, we explored the effect of vorapaxar on myocardial infarction (MI).. Methods and results. A blinded, independent central endpoint adjudication committee prospectively defined and classified MI according to the universal MI definition, including peak cardiac marker value (creatine kinase-MB [CK-MB] and/or troponin). Because the trial failed to meet its primary endpoint, these analyses are considered exploratory. During a median follow-up of 502 days, 1580 MIs occurred in 1319 patients. The majority (n = 1025, 64.9%) were type 1 (spontaneous) MI, followed by type 4a [percutaneous coronary intervention (PCI)-related] MI (n = 352; 22.3%). Compared with placebo, vorapaxar reduced the hazard of a first MI of any type by 12% [hazard ratio (HR), 0.88; 95% confidence ...
Since indium-111 platelet scintigraphy for the detection of left ventricular thrombosis often shows considerable non-specific blood pool activity a subtraction method using simultaneous technetium-99m blood pool scintigraphy was undertaken in 11 subjects with well documented remote myocardial infarction, who served as positive or negative controls, and in 18 consecutive patients with acute myocardial infarction. The results were compared with those of cross sectional echocardiography. Thirteen patients had transmural myocardial infarction and the calculated count per pixel in the left ventricle of the subtracted indium-111 platelet scintigram was (mean (SD)) 0.28(0.35), but five patients with subendocardial myocardial infarction had a mean count of 0.04(0.06). In seven patients with transmural myocardial infarction (two anterior and five inferior) left ventricular thrombosis was detected by indium-111 platelet scintigraphy but in only one of these by cross sectional echocardiography. None of the ...
TY - JOUR. T1 - Longitudinal trends in the severity of acute myocardial infarction. T2 - A population study in Olmsted County, Minnesota. AU - Hellermann, Jens P.. AU - Reeder, Guy S.. AU - Jacobsen, Steven J.. AU - Weston, Susan A.. AU - Killian, Jill M.. AU - Roger, Véronique L.. PY - 2002/8/1. Y1 - 2002/8/1. N2 - The mechanisms of the decline in coronary heart disease mortality are not fully elucidated. In particular, little is known about the trends in severity of myocardial infarction, which may have contributed to the mortality decline. This study examines indicators of myocardial infarction severity including Killip class, electrocardiogram descriptors, and peak creatine kinase values in a population-based, myocardial infarction incidence cohort to test the hypothesis that the severity of myocardial infarction declined over time. Between 1983 and 1994, 1,295 incident cases of myocardial infarction (mean age, 67 (standard deviation, 6) years; 43% women) occurred in Olmsted County, ...
On- vs. off-hours admission of patients with ST-elevation acute myocardial infarction undergoing percutaneous coronary interventions: data from a tertiary university brazilian hospital
Introduction: ST Segment Elevation Myocardial Infarction (STEMI) is largely due to plaque rupture (60-70% of cases) and plaque erosion (30-40%). Coronary inflammation plays a pivotal role in rupture, but the pathophysiology of erosion is unknown. Autopsy studies have shown that inflammatory infiltrates are much less abundant in erosion compared to rupture. We explored the hypothesis that differences in intracoronary cytokines can be demonstrated in vivo in the early phase of STEMI in patients undergoing primary percutaneous coronary intervention (PPCI).. Methods: We recruited 40 STEMI patients undergoing PPCI with in less than 6 hours of chest pain in a single-centre observational study. Blood samples were taken from the infarct-related artery using thrombus aspiration. Culprit plaques were imaged using optical coherence tomography (OCT) before PCI and classified by two blinded observers. The expression profiles of 102 cytokines were measured using an array, and comparisons of the two ...
Emerging evidence indicate that progenitor stem cells derived from bone marrow can be used to improve cardiac function in acute myocardial infarction patients. There is a great potential for stem cell therapy, using a variety of cell precursors to contribute to new blood vessel formation and muscle preservation in the myocardial infarct zone. The administration of cells via an infusion through the infarct related artery appears to be feasible and result in a clinical effect in some studies. Across the globe AMI is the leading cause of morbidity and mortality. This cannot be prevented by optimal standard therapies i.e. balloon or stent dilation of the infarct vessels.. The study is a double blind, placebo controlled, randomized, multicenter trial. Male or female patients between 18-75 years with first incidence of Acute Myocardial Infarction(AMI) and LVEF less than or equal to 40% are included in the study. Patients who have undergone successful percutaneous intervention (PCI) within ≤ 24 hours ...
TY - JOUR. T1 - Assisted ventilation during bystander CPR in a swine acute myocardial infarction model does not improve outcome. AU - Berg, Robert A.. AU - Kern, Karl B.. AU - Hilwig, Ronald W.. AU - Ewy, Gordon A.. PY - 1997/1/1. Y1 - 1997/1/1. N2 - Background: Mouth-to-mouth rescue breathing is a barrier to the performance of bystander cardiopulmonary resuscitation (CPR). We evaluated the need for assisted ventilation during simulated single-rescuer bystander CPR in a swine myocardial infarction model of prehospital cardiac arrest. Methods and Results: Steel cylinders were placed in the mid left anterior descending coronary arteries of 43 swine. Two minutes after ventricular fibrillation, animals were randomly assigned to 10 minutes of hand-bag-valve ventilation with 17% oxygen and 4% carbon dioxide plus chest compressions (CC+V), chest compressions only (CC), or no CPR (control group). Standard advanced life support was then provided. Animals successfully resuscitated received 1 hour of ...
RRH: Rural and Remote Health. Published article number: 2013 - Thrombolysis for acute ST elevation myocardial infarction: a pilot study comparing results from GP led small rural health emergency departments with results from a physician led sub-regional emergency department
Objectives. This study was designed to reassess the prediction of recurrent nonfatal myocardial infarction in patients recovering from acute myocardial infarction after thrombolysis.. Background. Recurrent nonfatal myocardial infarction is a strong and independent predictor of subsequent mortality. Current knowledge of risk factors for nonfatal reinfarction is still largely based on data gathered before the advent of thrombolysis. Thus, this prospective study was planned to identify harbingers of nonfatal reinfarction in the postinfarction patients of the multicenter Gruppo Italiano per lo Studio della Sopravvivenza nellInfarto Miocardico (GISSI-2) trial.. Methods. Predictors of nonfatal reinfarction at 6 months were analyzed by multivariate technique (Cox model) in 8,907 GISSI-2 survivors of myocardial infarction with clinical follow-up, relying on a set of prespecified variables reflecting residual ischemia, left ventricular failure or dysfunction, complex ventricular arrhythmias, comorbidity ...
Methods All studies published on the risk of MI during OC2 and OC3 use were analysed. For DVT the Committee for Proprietary Medicinal Products public assessment report published in 2001 and more recent studies published on this topic were used. The estimates of odds ratios (OR) for risk of death from DVT or MI were extracted from the published manuscripts. ORs were used to calculate the aetiological fraction of risk for death from DVT and MI in the population; the relative impact of OC3 compared to OC2 use was expressed as an excess risk of death overall and by age group for French women.. ...
1. Aronson D, Nassar M, Goldberg T, Kapeliovich M, Hammerman H, Azzam ZS. The impact of body mass index on clinical outcomes after acute myocardial infarction. Int J Cardiol. 2010;145:476-480. doi: 10.1016/j.ijcard.2009.12.029 20096942. 2. Kang WY, Jeong MH, Ahn YK, Kim JH, Chae SC, Kim YJ, et al. Obesity paradox in Korean patients undergoing primary percutaneous coronary intervention in ST-segment elevation myocardial infarction. J Cardiol. 2010;55:84-91. doi: 10.1016/j.jjcc.2009.10.004 20122553. 3. Kragelund C, Hassager C, Hildebrandt P, Torp-Pedersen C, Kober L. Impact of obesity on long-term prognosis following acute myocardial infarction. Int J Cardiol. 2005;98:123-131. 15676176. 4. Lazzeri C, Valente S, Chiostri M, Attana P, Picariello C, Sorini Dini C, et al. Impact of age on the prognostic value of body mass index in ST-elevation myocardial infarction. Nutr Metab Cardiovasc Dis. 2013;23:205-211. doi: 10.1016/j.numecd.2012.05.013 22901842. 5. OBrien EC, Fosbol EL, Peng SA, Alexander KP, ...
|p|The 12-lead surface electrocardiogram adjacent QTc dispersion, which is the maximum difference of corrected QT interval between two adjacent leads, is a simple method to determine regional variation in repolarization and refractoriness. The aim of this study is to evaluate adjacent QTc dispersion as a marker of susceptibility to ventricular arrhythmias after myocardial infarction. A total of 135 consecutive patients with acute myocardial infarction were enrolled in the study. Adjacent QTc, measured by lens magnifier, was calculated on the first, second and third days after acute myocardial infarction. On the second day after acute myocardial infarction, adjacent QTc dispersion was significantly greater in patients with ventricular arrhythmias (P < 0.001). Adjacent QTc dispersion on the first and fifth day after acute myocardial infarction was not associated with development of ventricular arrhythmias. On the second day after acute myocardial infarction, adjacent QTc dispersion is
No beneficial effect of intravenous enalaprilat followed by oral enalapril on mortality when administered within 24 hours post myocardial infarction. It is important to note in this study that follow-up was for 6 months only, possibly missing a late benefit due to ACE inhibitor therapy. The benefit of ACE inhibition appears most prominent for patients with anterior myocardial infarctions. This was a non-selective post myocardial infarction study without heart failure or left ventricular dysfunction on entry criterion. In ISIS-4 and GISSI-3, mortality improved by 0.46% and 0.8%, respectively, with risk reductions of 9% and 11%. In view of the risk of hypotension (20% in ISIS-4, compared with placebo 10%), very early ACE inhibition may benefit a highly selected subset of patients.. ...
Objective - The cause of increased post-AMI (acute myocardial infarction) mortality associated with depression remains poorly elucidated. The objective of this study was to examine the extent to which self-reported cardiac functional status accounted for depression-mortality associations following AMI.. Methods - Using a prospective cohort design (n = 1941), the authors obtained self-reported measures of depression and developed profiles of the patients pre-hospitalization cardiac risks, co-morbid conditions and drugs and revascularization procedures during or following index AMI hospitalization. To create these profiles, the patients self-reports were retrospectively linked to no less than 12 years worth of previous hospitalization data. Mortality rates 2 years after acute MI were examined with and without sequential risk adjustment for age, sex, income, cardiovascular risk, co-morbid conditions, selected process-of-care factors and self-reported cardiac functional status.. Results - ...
Whereas thrombus aspiration in patients with ST-elevation myocardial infarction (STEMI) is recommended by current guidelines, there are insufficient data to unequivocally support thrombectomy in patients with non-STEMI (NSTEMI). The Thrombus Aspiration in ThrOmbus containing culpRiT lesions in Non-ST-Elevation Myocardial Infarction (TATORT-NSTEMI) trial is a 400 patient, prospective, controlled, multicenter, randomized, open-label trial. The hypothesis is that under the background of early revascularization, adjunctive thrombectomy in comparison to conventional percutaneous coronary intervention (PCI) alone leads to less microvascular obstruction (MO) assessed by cardiac magnetic resonance imaging (CMR) in patients with NSTEMI. Patients will be randomized in a 1:1 fashion to one of the two treatment arms. The primary endpoint is the extent of MO assessed by CMR. Secondary endpoints include infarct size and myocardial salvage assessed by CMR, enzymatic infarct size as well as angiographic ...
Acute Myocardial infarction (AMI) at a young age (below 45 years) is rare and difficult to predict. We reported a fatal myocardial infarction from advanced atherosclerosis in a healthy young man who had no other major coronary risk factors except mild hypercholesterolemia. Thus, all available systemic risk scores identified him as a low risk candidate for developing a cardiovascular event. Autopsy revealed advanced atherosclerosis in all three major coronary arteries causing acute and old myocardial infarction. Thick epicardial adipose tissue and myocardial bridging of the mid left anterior descending artery were also noted. He frequently used etoricoxib to treat knee and back pain for consecutive five years. Potential mechanisms of sudden death from atherosclerosis, myo- cardial bridging, epicardial adipose tissue and selective COXIB are discussed in more detail below.. ...
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Title:Intracoronary Injection of Glycoprotein IIb/IIIa, Abciximab, as Adjuvant Therapy in Primary Coronary Intervention. VOLUME: 11 ISSUE: 2. Author(s):Andrea Rognoni, Alessadro Lupi, Chiara Cavallino, Roberta Rosso, Alessia Veia, Sara Bacchini and Angelo Sante Bongo. Affiliation:Coronary Care Unit and Catheterization Laboratory, Hospital Maggiore della Carita, Corso Mazzini 18, 28100 Novara, Italy.. Keywords:STEMI, Acute coronary syndrome, adjuvant therapy, bleeding, GP IIb/IIIa inhibitors, in - stent restenosis, no - reflow phenomenon, percutaneous coronary intervention, platelet, thrombosis.. Abstract:Acute coronary syndromes and, in paticular, ST - segment elevation myocardial infarction are the principle causes or mortality and morbidity in the industrialized countries. The manadgement of acute myocadial infarction is much debated in the literature; primary percutaneous coronary intervention is the treatment of choice. In the recent years there has been an increasing interest in the ...
The objectives are to examine if the excess risk of myocardial infarction from exposure to job strain is due to interaction between high demands and low control and to analyse what role such an interaction has regarding socioeconomic differences in risk of myocardial infarction. The material is a population-based case-referent study having...
Mahaffey KW, Held C, Wojdyla D, James S, Katus H, Husted S, Steg PG, Cannon CP, Becker R, Storey R, Khurmi N, Nicolau JC, Cheuk-Man Y, Ardissimo D, Budaj A, Morais J, Montgomery D, Himmelmann A, Harrington R, Wallentin L. Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial. Journal of the American College of Cardiology. 2014 ; 63( 11): 1493-1499 ...
Patients with symptoms suggestive of an acute myocardial infarction (MI) and having electrocardiographic evidence of an acute MI manifested by ST elevations (>1 mm in two contiguous leads afterto rule out coronary vasospasm) that is considered to rep
Patients with symptoms suggestive of an acute myocardial infarction (MI) and having electrocardiographic evidence of an acute MI manifested by ST elevations (>1 mm in two contiguous leads afterto rule out coronary vasospasm) that is considered to rep
Symptom-to-door time in ST segment elevation myocardial infarction: overemphasized or overlooked? Results from the AMI-McGill study. Can J Cardiol. 2008 Mar; 24(3):213-6 ...
Background. Acute myocardial infarction is a major cause of death and morbidity worldwide, both in women and in men. Up to the age of 70 the incidence of acute myocardial infarction is higher in men than in women. Although the incidence is lower in young women than in young men, young women are particularly vulnerable due to higher fatality rates. The lower incidence in women compared to men might underestimate womens risk. Women might also be less likely to identify themselves as possible sufferers and to take cardio-protective actions.. The treatment of acute myocardial infarction has changed dramatically the last decades and reperfusion therapy has great impact on myocardial damage. The most critical time of an acute myocardial infarction is the very early phase, as rapid treatment is significantly associated with reduced mortality. Time has therefore become an important issue regarding the patients prognosis. These patients often delay in seeking medical assistance, and this patient ...
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SUMMARY A seasonal pattern with winter peak in acute myocardial infarction incidence and cardiovascular disease risk factors is observed in studies worldwide. However, several previous studies have methodical limitations and few are performed in cold climate areas. The aim of this thesis is to assess the effect of season and meteorological factors on first-ever myocardial infarction and the seasonal variation in cardiovascular disease risk factors in a subarctic adult population with long-term follow-up, using appropriate methods with adjudicated outcomes and well-defined exposures. The population-based Tromsø Study consists of more than 40,000 individuals living in a subarctic climate in Northern Norway. The cohort members have been examined up to nine times in six repeated health surveys in the years between 1974 and 2008. Data on myocardial infarction and risk factors have been collected throughout follow-up. The thesis consists of three studies. The first study is an analysis of the ...
TY - JOUR. T1 - Risk stratification after acute myocardial infarction by means of exercise two-dimensional echocardiography. AU - Ryan, Thomas. AU - Armstrong, William F.. AU - ODonnell, Jacqueline A.. AU - Feigenbaum, Harvey. PY - 1987/12. Y1 - 1987/12. N2 - To determine whether exercise two-dimensional echocardiography contributes to the prognostic information provided by exercise testing in patients recovering from acute myocardial infarction, 40 patients were prospectively studies by means of pre- and postexercise echocardiography 10 to 21 days after myocardial infarction. Patients were followed for 6 to 10 months or until one of the following clinical end points occurred: death, recurrent myocardial infarction, unstable angina, or coronary artery bypass grafting. Results of treadmill exercise tests were negative in 13 of 20 patients with good clinical outcome (65% specificity) and positive in 11 of 20 patients with poor clinical outcome (55% sensitivity). The resting echocardiogram was ...
OBJECTIVE--The SAVE study showed that captopril improves mortality in patients with left ventricular dysfunction after myocardial infarction and that this benefit occurred even in patients with no clinically overt heart failure. On the basis of this, it seems important to identify correctly which patients have left ventricular dysfunction after a myocardial infarction. The objective was to compare various methods of identifying patients with left ventricular dysfunction (left ventricular ejection fraction, LVEF, , or = 40%) after acute myocardial infarction. The methods compared were echocardiography (quantitative and qualitative visual assessment), clinical evaluation (subjective assessment and three clinical score methods), and measurement of plasma concentrations of cardiac natriuretic peptide hormones (atrial and brain natriuretic peptides, ANP and BNP). DESIGN--Cross sectional study of left ventricular function in patients two to eight days after acute myocardial infarction. ...
Background and Objectives: Metabolic syndrome (MetS) is an important risk factor for cardiovascular disease. However, the clinical outcome of acute myocardial infarction (AMI) with MetS has not been well examined. The purpose of this study was to evaluate the clinical outcomes of AMI patients with MetS. Subjects and Methods: We evaluated a total of 6352 AMI patients who had successful percutaneous coronary interventions and could be identified for MetS between 2005 and 2008 at 51 hospitals participating in the Korea Acute Myocardial Infarction Registry. They were divided into 2 groups according to the presence of MetS: the MetS group (n=2493, 39.2%) versus the Non-MetS group (n=3859, 60.8%). In addition, 4049 AMI patients with high levels of low density lipoprotein-cholesterol (LDL-C) (��100 mg/dL) among them, were divided into the MetS group (n=1561, 38.6%) versus the Non-MetS group (n=2488, 61.4%). Results: In the overall population, there was no significant difference in 12-month the ...
Heart attack treatment may involve primary percutaneous transluminal coronary angioplasty (PTCA). Heart attack treatment information developed by physicians.
TY - JOUR. T1 - Survival of patients undergoing rescue percutaneous coronary intervention. AU - Burjonroppa, Sukesh C.. AU - Varosy, Paul D.. AU - Rao, Sunil V.. AU - Ou, Fang Shu. AU - Roe, Matthew. AU - Peterson, Eric. AU - Singh, Mandeep. AU - Shunk, Kendrick A.. PY - 2011/1. Y1 - 2011/1. N2 - Objectives This study sought to develop a tool for predicting an individuals risk of mortality following rescue percutaneous coronary intervention (PCI). Background Although fibrinolytic therapy is appropriate and improves survival for certain ST-segment elevation myocardial infarction patients, a substantial proportion suffer ongoing myocardial ischemia, a class I indication for emergent percutaneous coronary intervention (rescue PCI). Methods Using the National Cardiovascular Data Registry (NCDR), rescue PCI was defined as nonelective PCI following failed fibrinolysis in patients with continuing or recurrent myocardial ischemia. Multivariable logistic regression was used to determine mortality ...
Acute coronary syndrome continues to be a significant cause of morbidity and mortality in the United States. Family physicians need to identify and mitigate risk factors early, as well as recognize and respond to acute coronary syndrome events quickly in any clinical setting. Diagnosis can be made based on patient history, symptoms, electrocardiography findings, and cardiac biomarkers, which delineate between ST elevation myocardial infarction and non-ST elevation acute coronary syndrome. Rapid reperfusion with primary percutaneous coronary intervention is the goal with either clinical presentation. Coupled with appropriate medical management, percutaneous coronary intervention can improve short- and long-term outcomes following myocardial infarction. If percutaneous coronary intervention cannot be performed rapidly, patients with ST elevation myocardial infarction can be treated with fibrinolytic therapy. Fibrinolysis is not recommended in patients with non-ST elevation acute coronary syndrome;
TY - JOUR. T1 - What is the best anticoagulant therapy during primary percutaneous coronary intervention for acute myocardial infarction?. AU - Gurbel, Paul A.. AU - Navarese, Eliano Pio. AU - Tantry, Udaya S.. N1 - Publisher Copyright: Copyright © by Medycyna Praktyczna, Kraków 2015.. PY - 2015. Y1 - 2015. N2 - Both ST-segment elevation myocardial infarction and percutaneous coronary intervention (PCI) are associated with a highly prothrombotic state, and thrombin plays a critical role during occlusive clot generation and subsequent occurrence of an ischemic event. Therefore, a strategy of anticoagulation plus dual antiplatelet therapy has been regarded as de facto standard therapy during primary PCI (pPCI). Recently, there has been great controversy surrounding the role of bivalirudin versus unfractionated heparin in pPCI. Earlier, the results of the HORIZONS-AMI trial, particularly those regarding the long-lasting mortality benefit, provided a strong rationale for recommending bivalirudin ...
OBJECTIVES: This study sought to evaluate the effect of early intravenous metoprolol on left ventricular (LV) strain assessed with feature-tracking cardiovascular magnetic resonance (CMR). BACKGROUND: Early intravenous metoprolol before primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) portends better outcomes in the METOCARD-CNIC (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction) trial. METHODS: A total of 197 patients with acute anterior STEMI who were enrolled in the METOCARD-CNIC trial (100 allocated to intravenous metoprolol before primary PCI and 97 control patients) were evaluated. LV global circumferential strain (GCS) and global longitudinal strain (GLS) were measured with feature-tracking CMR at 1 week and 6 months after STEMI and compared between randomization groups. RESULTS: Patients who received early intravenous metoprolol had significantly more preserved LV strain compared with the control patients ...
Arachidonic acid (AA), a precursor of prothrombotic eicosanoids, is potentially atherogenic, but epidemiologic data are scarce. We evaluated the hypothesis that increased AA in adipose tissue is associated with increased risk of nonfatal acute myocardial infarction (MI), and if so, whether this association is related to dietary or adipose tissue linoleic acid. We studied the association between AA and MI in 466 cases of a first nonfatal acute MI, matched on age, gender, and residence to 466 population controls. Fatty acids (FA) were assessed by GC in adipose tissue samples collected from all subjects. Odds ratios (OR) and 95% CI were calculated from multivariate conditional logistic regression models. Subjects in the highest quintile of adipose tissue AA (0.64% of total FA) had a higher risk of nonfatal acute MI than those in the lowest quintile (0.29% of total FA), after adjusting for potential confounders including (n-3) and trans FAs (OR=1.94, 95% CI: 1.07, 3.53, P for trend = 0.026). Adipose ...
TY - JOUR. T1 - Pentraxin 3 in unstable angina and non-ST-segment elevation myocardial infarction. AU - Matsui, Shigeru. AU - Ishii, Junichi. AU - Kitagawa, Fumihiko. AU - Kuno, Atsuhiro. AU - Hattori, Kousuke. AU - Ishikawa, Makoto. AU - Okumura, Masanori. AU - Kan, Shino. AU - Nakano, Tadashi. AU - Naruse, Hiroyuki. AU - Tanaka, Ikuko. AU - Nomura, Masanori. AU - Hishida, Hitoshi. AU - Ozaki, Yukio. PY - 2010/5/1. Y1 - 2010/5/1. N2 - Purpose: We prospectively investigated the prognostic value of pentraxin 3 (PTX3) in patients with unstable angina and non-ST-segment elevation myocardial infarction (UA/NSTEMI). Background: PTX3 may be a useful marker for localized vascular inflammation and damage to the cardiovascular system. Recent studies have shown that plasma PTX3 is elevated in patients with UA/NSTEMI; however, its prognostic value in UA/NSTEMI remains unclear. Methods: PTX3, high-sensitivity C-reactive protein (hsCRP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and cardiac ...
TY - JOUR. T1 - Resuscitative endovascular balloon occlusion of the aorta during non-ST elevation myocardial infarction. T2 - A case report. AU - Curtis, Eleanor E.. AU - Russo, Rachel M.. AU - Nordsieck, Eric. AU - Johnson, Michael. AU - Williams, Timothy K.. AU - Neff, Lucas P.. AU - Hile, Lisa. AU - Galante, Joseph M. AU - Dubose, Joseph J.. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a hemorrhage control technique that is increasingly being adopted for the management of noncompressible bleeding. In addition to limiting hemorrhage, REBOA increases blood flow to the heart, lungs, and brain. A small number of case reports and animal studies describe the use of REBOA to increase coronary perfusion during cardiopulmonary resuscitation. We report a case in which REBOA may have reversed ST-segment abnormalities during a Type II non-ST elevation myocardial infarction (NSTEMI) in a patient with previous trauma. We describe the presentation, ...
TY - JOUR. T1 - Echocardiography in acute myocardial infarction.. AU - Quinones, M. A.. PY - 1984/2. Y1 - 1984/2. N2 - Echocardiography has recently gained increasing popularity as a noninvasive technique to assess left ventricular function and regional wall motion in acute myocardial infarction. Detection of regional dyssynergy is possible in over 90 per cent of patients with acute infarction, allowing assessment of site and extent of involvement. Estimates of severity of left ventricular dysfunction on admission into the coronary care unit allow stratification of patients into risk categories in terms of acute and long-term prognosis. Complications of myocardial infarction such as right ventricular infarction, ventricular septal rupture, papillary muscle rupture, papillary muscle dysfunction, formation of mural thrombi, ventricular aneurysms, and pericardial effusion can be diagnosed echocardiographically at the bedside. This article discusses these applications as well as some of the ...
Amin AP, Salisbury AC, McCullough PA, et al. Trends in the incidence of acute kidney injury in patients hospitalized with acute myocardial infarction. Arch Intern Med. 2012;172:246-253. Available at: http://archinte.ama-assn.org/cgi/content/full/172/3/246.. Hsu RK, Hsu C. Acute kidney injury: comment on Trends in the incidence of acute kidney injury in patients hospitalized with acute myocardial infarction. Arch Intern Med. 2012;172:253-254.. Parikh CR, Coca SG, Wang Y, et al. Long-term prognosis of acute kidney injury after acute myocardial infarction. Arch Intern Med. 2008;168:987-995.. Aengus Murphy C, Robb SD, Weir RA, et al. Declining renal function after myocardial infarction predicts poorer long-term outcome. Eur J Cardiovasc Prev Rehabil. 2010;17:181-186.. Chertow GM, Burdick E, Honour M, et al. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol. 2005;16:3365-3370.. Molitoris BA, Levin A, Warnock DG; et al, Acute Kidney Injury Network ...
It is now widely accepted that for patients with ST-segment elevation myocardial infarction (STEMI), primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy if it can be delivered in a timely fashion. Based on robust evidence documenting a relationship between time-to-reperfusion (defined either by time between symptom onset or hospital arrival and reperfusion) and mortality (1,2), the American College of Cardiology/American Heart Association guidelines recommend that STEMI patients undergo primary PCI with a balloon inflation or device time within 90 min of first medical contact (3). Moreover, in the most recent focused update of the STEMI guidelines, it is recommended that each community develop a STEMI system of care that includes: 1) a process for pre-hospital identification of STEMI and catheterization laboratory activation; 2) destination protocols for STEMI-receiving centers; and 3) transfer protocols for patients who arrive at STEMI referral centers and are ...
Summary Circulating procoagulant microparticles (MP) were measured as markers of vascular damage and prothrombotic risk in patients undergoing ST-segment myocardial infarction (STEMI) treated by primary percutaneous transluminal coronary angioplasty (PTCA) and additional GPIIb-IIIa antagonists. Cel...
Thesis, English, ASPIRATION THROMBECTOMY DURING PRIMARY PERCUTANEOUS CORONARY INTERVENTION AS ADJUNCTIVE THERAPY TO EARLY (IN AMBULANCE) ABCIXIMAB ADMINISTRATION IN PATIENTS WITH ACUTE ST ELEVATION MYOCARDIAL INFARCTION AN ANALYSIS from LEIDEN MISSION! ACUTE MYOCARDIAL INFARCTION TREATMENT OPTIMIZATION PROGRAM for Ahmed Tarek Abdel Hameed Nagib
Bed rest is an inherent part of treatment for acute myocardial infarction (AMI). In clinical practice this intervention is prescribed in different ways and for different lengths of time. Current guidelines recommend at least 12 hours bed rest following AMI. However the basis for these recommendations is unclear. This review found 15 trials which were generally outdated and of moderate to poor methodological quality. Bed rest ranging from 2 to 12 days appears to be as safe as longer periods of bed rest. No evidence was found to support the current bed rest recommendations of not more than 12 to 24 hours. The optimal duration of bed rest after AMI remains undetermined from the available evidence.. ...
ENGLISH ABSTRACT: A heart attack is a medical emergency and a life threatening disease. Patients with chest pain and a possible diagnosis of myocardial infarction require a detailed assessment and prompt medical management. The aim of the study was to determine the in-hospital delay in administrating thrombolytic therapy to patients with acute myocardial infarction (AMI) A mixed method with convergent parallel design was applied to the study. The population consisted of N=63 case notes of adult patients diagnosed with acute myocardial infarction and who had received thrombolytic therapy. The other population included (n=8) registered professional nurses working in the coronary care unit (CCU) of a tertiary hospital in the Western Cape. A record review was done using a data extraction form and semi-structured interview guide was used for data collection purposes. Reliability and validity was tested by the use of a nurse expert and a statistician. The nurse expert evaluated the data extraction ...
TY - JOUR. T1 - High Exercise Capacity Attenuates the Risk of Early Mortality After a First Myocardial Infarction. T2 - The Henry Ford Exercise Testing (FIT) Project. AU - Shaya, Gabriel E.. AU - Al-Mallah, Mouaz H.. AU - Hung, Rupert K.. AU - Nasir, Khurram. AU - Blumenthal, Roger S.. AU - Ehrman, Jonathan K.. AU - Keteyian, Steven J.. AU - Brawner, Clinton A.. AU - Qureshi, Waqas T.. AU - Blaha, Michael J.. PY - 2016/2/1. Y1 - 2016/2/1. N2 - Objective To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI). Patients and Methods This retrospective cohort study included 2061 patients without a history of MI (mean age, 62±12 years; 38% [n=790] women; 56% [n=1153] white) who underwent clinical treadmill stress testing in the Henry Ford Health System from January 1, 1991, through May 31, 2009, and suffered MI during follow-up (MI event proportion, 3.4%; mean time from the exercise test to MI, 6.1±4.3 years). Exercise ...
A 41-year-old male bodybuilder was admitted with acute inferior myocardial infarction. The patient had been using oxymetholone and methenolone to increase his performance for 15 years and quitted smoking three years before. He underwent successful primary percutaneous coronary intervention (PCI) and …
The discrepancy between the relatively better early outcomes and the similar or even worse long-term prognoses in patients with non-Q wave versus Q wave infarction has led to a more aggressive approach in the management of this group of patients ([3, 5, 10]). Our findings conflict somewhat with reports from the prethrombolytic era ([3-5, 9, 17-19]), in which 1-year mortality was similar or even higher in the non-Q wave infarction populations. The difference could be related to the heterogeneity of the populations, the definitions used and the use of thrombolysis ([3-9, 11]).. Another possible explanation for this disagreement is the initial ST segment deviation. In most studies of Q wave or non-Q wave infarction, the initial ST segment shift was seldom considered a prognostic marker. The observation that patients with initial ST segment depression have a worse prognosis than those with ST segment elevation and either Q wave or non-Q wave infarction ([20-23]), with the additional evidence that ...
The dilemma of refractory hypoxemia after inferior wall myocardial infarction. Proc (Bayl Univ Med Cent). 2018 Jan;31(1):67-69 Authors: Albaghdadi A, Teleb M, Porres-Aguilar M, Porres-Munoz M, Marmol-Velez A Abstract Patent foramen ovale (PFO) occurs in 25% of people. The decision on whether to close the PFO found after myocardial infarction and specifically right ventricular...
OBJECTIVES: Our goal was to validate myocardium at risk on T2-weighted short tau inversion recovery (T2-STIR) cardiac magnetic resonance (CMR) over time, compared with that seen with perfusion single-photon emission computed tomography (SPECT) in patients with ST-segment elevation myocardial infarction, and to assess the amount of salvaged myocardium after 1 week. BACKGROUND: To assess reperfusion therapy, it is necessary to determine how much myocardium is salvaged by measuring the final infarct size in relation to the initial myocardium at risk of the left ventricle (LV). METHODS: Sixteen patients with first-time ST-segment elevation myocardial infarction received (99m)Tc tetrofosmin before primary percutaneous coronary intervention. SPECT was performed within 4 h and T2-STIR CMR within 1 day, 1 week, 6 weeks, and 6 months. At 1 week, patients were injected with a gadolinium-based contrast agent for quantification of infarct size. RESULTS: Myocardium at risk at occlusion on SPECT was 33 +/- ...
Background In-stent restenosis is considered to be a gradual and progressive condition and there is scant data on myocardial infarction (MI) as a clinical presentation. Methods and Results Of 2,462 consecutive patients who underwent percutaneous coronary intervention between June 2001 and December 2002, clinical in-stent restenosis occurred in 212 (8.6%), who were classified into 3 groups: ST elevation MI (STEMI), non-ST elevation MI (NSTEMI) and non-MI. Of the 212 patients presenting with clinical in-stent restenosis, 22 (10.4%) had MI (creatine kinase (CK) ≥2 × baseline with elevated CKMB). The remaining 190 (89.6%) patients had stable angina or evidence of ischemia by stress test without elevation of cardiac enzymes. Median interval between previous intervention and presentation for clinical in-stent restenosis was shorter for patients with MI than for non-MI patients (STEMI, 90 days; NSTEMI, 79 days; non-MI, 125 days; p=0.07). Diffuse in-stent restenosis was more frequent in MI patients ...
Background. Emerging evidence suggests that stem cells and progenitor cells derived from bone marrow can be used to improve cardiac function in patients after acute myocardial infarction. In this randomised trial, we aimed to assess whether intracoronary transfer of autologous bone-marrow cells could improve global left-ventricular ejection fraction (LVEF) at 6 months follow-up.. Methods. After successful percutaneous coronary intervention (PCI) for acute ST-segment elevation myocardial infarction, 60 patients were randomly assigned to either a control group (n=30) that received optimum postinfarction medical treatment, or a bone-marrow-cell group (n=30) that received optimum medical treatment and intracoronary transfer of autologous bone-marrow cells 4·8 days (SD 1·3) after PCI. Primary endpoint was global left-ventricular ejection fraction (LVEF) change from baseline to 6 months follow-up, as determined by cardiac MRI. Image analyses were done by two investigators blinded for treatment ...
BACKGROUND: Chronic kidney disease is associated with increased risk of mortality. We examined the impact of moderate and severe renal insufficiency (RI) on short- and long-term mortality among unselected patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). METHODS: From January 1, 2002 to December 31, 2010 all patients with STEMI treated with primary PCI were identified. The hazard ratio (HR) for death was estimated using a Cox regression model, controlling for potential confounders. RI was defined as creatinine clearance (CrCl) , 60 mL/min (moderate RI: CrCl ≤30 , 60 mL/min and severe RI: CrCl , 30 mL/min). RESULTS: The study cohort consisted of 4,116 patients of whom 898 (21.8%) had RI and 3,218 (78.2%) had a CrCl ≥ 60 mL/min. Compared to patients without RI, patients with RI were older, more often female and more likely to have diabetes mellitus, hypertension and to present with a higher Killip class.Among ...
Acute myocardial infarction (AMI) is one of the most deleterious conditions leading to cardiovascular diseases and mortality. The importance of an early and accurate diagnosis assures immediate medical treatments, which are fundamental to reduce mortality and improve prognoses. AMI is associated to an inflammatory response which includes the increase of circulating inflammatory cytokines, chemokines and immune cell activation. This study aimed to identify which are the very early immune-related biomarkers that may be used as predictors of myocardial infarction severity. In order to mimic the pathophysiological events involved in human myocardial infarction, a temporary occlusion (90 min) of the mid-left anterior descending coronary artery was performed in a swine animal model. Lymphocyte subsets analysis in peripheral blood revealed significant alterations in CD4+/CD8+ ratio and naïve and effector/memory T cell percentages at 1 h post-myocardial infarction. Changes in TH1/TH2-related cytokine, monocyte
Aims: IL-1b-3953 C,T and MMP-9-1562C,T variants have been shown to be linked to the development of myocardial infarction (MI), although previous studies have reported inconsistent results. The aim of the present study was to determine whether these genetic variations are associated with MI susceptibility in an Iranian population. Methods: In the current study, 117 patients with MI and 120 control group members were selected as participants. Peripheral blood samples were taken from all the subjects for genomic DNA extraction. Single nucleotide polymorphism (SNP) genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assays. Results: Multiple logistic regression analysis revealed that the TT genotype of the IL-1b-3953 C,T polymorphism is associated with a significant MI protective effect in: the homozygote model after adjustment for MI risk factors (odds ratio OR]: 0.18, confidence interval 95% CI] = 0.04-0.72; p = 0.01); and also in the recessive ...
Background Recent trials in acute myocardial infarction indicate that intensive and early statin therapy that lowers low-density lipoprotein cholesterol (LDL-C) to ≤ 70 mg dL−1 is beneficial. The combination of statins with ezetimibe, a newly developed cholesterol-absorption inhibitor, can lead to a further reduction in LDL-C of up to 26%. In this study, we examined the rapidity and intensity of the lipid-lowering effect of ezetimibe co-administered with simvastatin immediately after myocardial infarction.. Materials and methods Sixty patients admitted for acute myocardial infarction were randomized to receive either simvastatin 40 mg (SIMVA), a combination of simvastatin 40 mg and ezetimibe 10 mg (EZE/SIMVA), or no lipid-lowering drugs (NLLD) and had their lipid levels assessed 2, 4 and 7 days later.. Results At baseline, cardiovascular risk factors were similar in all three groups [mean (SD) LDL-C of 141 (36) mg dL−1]. At days 2 , 4 and 7 there was no significant change in mean LDL-C ...
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was as follows: is coronary artery bypass graft (CABG) surgery superior to percutaneous coronary intervention (PCI) in terms of in Show moreA best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was as follows: is coronary artery bypass graft (CABG) surgery superior to percutaneous coronary intervention (PCI) in terms of in-hospital mortality and morbidity and long-term outcomes in patients with acute myocardial infarction (MI)? A total of 104 papers were returned using the selected search. Of these, six represented the best evidence to answer the clinical question. The selection criteria were comparative studies with only PCI and CABG groups in patients with acute MI. Case reports, reviews, recommendations and studies on a specific population or out of the context of acute MI were excluded. The authors, journal, date and country ...
Periprocedural myocardial infarction enhances the predictive value of inflammatory biomarkers for patients with obstructive coronary artery disease after implantation of drug-eluting stent Anastasia Jesika,1 Zuo-Ying Hu,2 Jing Kan,3 Shao-Liang Chen2 1Nanjing Medical University, Nanjing, Peoples Republic of China; 2Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Peoples Republic of China; 3Nanjing Heart Center, Nanjing, Peoples Republic of China Objective: The present study aims to clarify the long-term clinical importance of interleukin (IL)-6 in predicting major adverse cardiac events (MACE) for an entire cohort of patients with coronary artery disease after implantation of a drug-eluting stent (DES), and its interplay with periprocedural myocardial infarction (PMI). Background: The correlation of proinflammatory biomarkers with occurrence of clinical events, including PMI and mortality, is controversial. Methods: IL-6 was measured in 1,991 patients at
Background: There are few studies which compare the efficacy and safety of the Resolute Onyx zotarolimus-eluting stent (O-ZES) and everolimus-eluting stent (EES) in patients with acute myocardial infarction (AMI). Therefore, the present study aimed to compare clinical outcomes of O-ZES and EES in patients with AMI undergoing successful percutaneous coronary intervention (PCI). Methods: From January 2016 to December 2016, the Korea Acute Myocardial Infarction Registry (KAMIR) enrolled 3,364 consecutive patients. Among them, O-ZES was used in 402 patients and EES was used in 1,084 patients. The primary endpoint was target lesion failure (TLF), as defined by composite of cardiac death, target vessel myocardial infarction (TV-MI), and ischemic driven-target lesion revascularization (ID-TLR) at 6 month clinical follow-up. Results: At 6 months, the incidence of TLF was not significantly different between O-ZES and EES group (4.0% vs. 3.9%, adjusted hazard ratio [HR] 1.17, 95% confidential interval ...
OBJECTIVES: Compare gender disparities in ST-elevation myocardial infarction (STEMI) regarding first medical contact (FMC) and prehospital delay times and explore factors associated with prehospital delay in men and women separately.. DESIGN: Cross-sectional study based on medical records and a validated questionnaire. Eligible patients were enrolled within 24 hours after admittance to hospital.. SETTING: Patients were included from November 2012 to January 2014 from five Swedish hospitals with catheterisation facilities 24/7.. PARTICIPANTS: 340 men and 109 women aged between 31 and 95 years completed the survey.. MAIN OUTCOME MEASURES: FMC were divided into five possible contacts: primary healthcare centre by phone or directly, national advisory nurse by phone, emergency medical services (EMS) and emergency room directly. Two parts of prehospital delay times were studied: time from symptom onset to FMC and time from symptom onset to diagnostic ECG.. RESULTS: Women more often called an advisory ...
BACKGROUND/AIM: Acute myocardial infarction (AMI) is associated with increased coagulation which in the presence of unstable atheroma or endothelial damage leads to occlusive coronary vessel thrombosis. AMI is usually characterized by increased levels of catecholamines. It is possible there may be a link between catecholamines and hypercoagulation, but this still remains to be determined. In the current study we sought to verify whether hypercoagulation is associated with hypersympathetic activity in AMI patients, and whether there is a correlation between increased Methoxyhydroxyphenylglycol (MOPEG) levels (a metabolite of catecholamines) and shorter APTT (a marker of hypercoagulation). RESULTS: Shorter APTT values were detected in the plasma of AMI patients, which had also increased MOPEG levels. A linear correlation between APTT and MOPEG values was observed. High levels of the coagulation marker prothrombin (fragments 1+2) were also found. CONCLUSION: Shortened APTT demonstrates ...
TY - JOUR. T1 - Characteristics and prognosis of patients with suspected acute myocardial infarction and elevated MB relative index but normal total creatine kinase. AU - Lloyd-Jones, Donald M.. AU - Camargo, Carlos A.. AU - Giugliano, Robert P.. AU - Walsh, Craig R.. AU - ODonnell, Christopher J.. PY - 1999/11/1. Y1 - 1999/11/1. N2 - MB Leak patients who develop an elevated MB relative index with a normal total creatine kinase (CK) level are not as well characterized as those who have diagnostic enzyme elevations in the setting of ST elevation (↑) or non-ST↑ acute myocardial infarction (AMI). During a 1-year period, we studied all patients hospitalized in an urban academic hospital with suspected AMI who developed an elevated MB relative index within 24 hours of presentation. Of 595 patients, 44% had MB Leak, 34% had non-ST↑ AMI and 22% had ST↑ AMI. Patients with MB Leak and non-ST↑ AMI were significantly older than those with ST↑ AMI (mean ages 69, 71, and 63 years, ...
Objectives The aim of this study was to examine the level of agreement between acute instantaneous wave-free ratio (iFR) measured across nonculprit stenoses in patients with ST-segment elevation myocardial infarction (STEMI) and iFR measured at a staged follow-up procedure. Background Acute full revascularization of nonculprit stenoses in STEMI is debated and currently guided by angiography. Acute functional assessment of nonculprit stenoses may be considered. Methods Immediately after successful primary culprit intervention for STEMI, nonculprit coronary stenoses were evaluated with iFR and left untreated. Follow-up evaluation with iFR was performed at a later stage. iFR ,0.90 was considered hemodynamically significant. Results One hundred twenty patients with 157 nonculprit lesions were included. Median acute iFR was 0.89 (interquartile range [IQR]: 0.82 to 0.94; n = 156), and median follow-up iFR was 0.91 (interquartile range: 0.86 to 0.96; n = 147). Classification agreement was 78% between ...
TY - JOUR. T1 - Joint effect of physical activity and body mass index on mortality for acute myocardial infarction in the elderly. T2 - Role of preinfarction angina as equivalent of ischemic preconditioning. AU - Abete, Pasquale. AU - Cacciatore, Francesco. AU - Della Morte, David. AU - Mazzella, Francesca. AU - Testa, Gianluca. AU - Galizia, Gianluigi. AU - De Santis, Domenico. AU - Longobardi, Giancarlo. AU - Ferrara, Nicola. AU - Rengo, Franco. PY - 2009/2/1. Y1 - 2009/2/1. N2 - BACKGROUND: Preinfarction angina (PrA), clinical equivalent of ischemic preconditioning, confers protection against in-hospital mortality for acute myocardial infarction (AMI) in adult but not in elderly patients. This study aims to examine the interaction between physical activity and body mass index (BMI) in preserving the cardioprotective effect of PrA in elderly patients with AMI. DESIGN: Elderly patients (≥65 years old) with AMI admitted to Coronary Care Unit. METHODS: Elderly patients with AMI were ...
Comparison of drug-eluting stents versus bare-metal stents for treating ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2008 Jun; 1(3):227-32 ...
... myocardial infarction; unanticipated reactions to the medications used during the procedure; damage to the conduction system, ...
"Myocardial Infarction". (Retrieved 29 November 2006) Introduction to Antibodies - Enzyme-Linked Immunosorbent Assay (ELISA). ( ...
Some patients, especially elderly and diabetics, may present with what is known as a painless myocardial infarction or a " ... Retrieved November 22, 2006 Davis TM, Fortun P, Mulder J, Davis WA, Bruce DG (2004). "Silent myocardial infarction and its ... Cervero F" Gut 2000; 47:56-57 Mallinson, T (2010). "Myocardial Infarction". Focus on First Aid (15): 15. Retrieved 2010-06-08. ... Myocardial ischemia, the most frequent cause of cardiac pain, is the most common cause of death in the United States. Urinary ...
Some of these conditions include: •Allergic reactions •Stroke •Sepsis •Myocardial infarction •Colitis, inflammation of the ...
Later, they were found useful for other cardiovascular and kidney diseases including: Acute myocardial infarction (heart attack ... ISBN 978-0-07-142280-2. "Myocardial Infarction". The Lecturio Medical Concept Library. Retrieved 27 August 2021. "Congestive ... demonstrated an ability to reduce the mortality rates of patients with a myocardial infarction and to slow the subsequent ... or Both After Myocardial Infarction". Circulation. 111 (25): 3411-3419. doi:10.1161/CIRCULATIONAHA.104.508093. PMID 15967846. ...
Myocardial infarction Myocardial ischaemia Baroldi, Giorgio (2004). The Etiopathogenesis of Coronary Heart Disease: A Heretical ... ISBN 978-94-009-3209-8. Leone, A (2017). "Myocardial Infarction. Pathological Relevance and Relationship with Coronary Risk ... During the process, myocardial cells are stretched and stressed to produce new contractile elements. In colliquative ... It is considered an indicator of acute myocardial ischemia and can be used to confirm ischemia in the absence of other ...
February 2018). "Mental Stress-Induced-Myocardial Ischemia in Young Patients With Recent Myocardial Infarction: Sex Differences ... A myocardial infarction carries a greater than five-fold increase in relative risk for developing heart failure. If coronary ... This is known as myocardial infarction. A heart attack can cause arrhythmias, as well as permanent damage to the heart muscle. ... Lack of oxygen may also result in a myocardial infarction (heart attack). CAD can be contracted over time. Risk factors include ...
The symptoms tend to occur 2-3 weeks after myocardial infarction but can also be delayed a few months. It tends to subside in a ... Dressler W (January 1959). "The post-myocardial-infarction syndrome: a report on forty-four cases". Arch Intern Med. 103 (1): ... Dressler syndrome was historically a phenomenon complicating about 7% of myocardial infarctions, but in the era of percutaneous ... Jaffe, AS; Boyle, AJ (2009). "Acute Myocardial Infarction". In Crawford, Michael H. (ed.). CURRENT Diagnosis & Treatment: ...
Cardiovascular: Myocardial infarction; stroke; heart block; arrhythmias; hypotension, particularly orthostatic hypotension; ...
If the myocardial infarction is treated with thrombolytic therapy, the mortality increases to over 70%, mostly due to bleeding ... Mechanic O, Gavin M, Grossman S (9 March 2021). "Acute Myocardial Infarction". National Center for Biotechnology Information, U ... obstructive shock Past history of myocardial infarction History of kidney failure (either acute or chronic kidney failure) The ... Infarction is caused by the involvement of the coronary arteries, which supply the heart with oxygenated blood, in the ...
Myocardial infarction heart attack. The words mean heart muscle blockage. Myo-inositol A substance in the cell that is thought ... Broken pieces of those deposits or closure of the arterial opening can cause myocardial infarction or stroke. Precisely what ...
Myocardial infarction in Nigerians. Tropical and geographical medicine. 1973;25(2):147-50. Falase AO, Oladapo OO, Kanu EO. ... Relatively low incidence of myocardial infarction in Nigerians. Cardiologie tropicale. 2001;27(107):45-7. Ogah OS, Adebayo O, ... Cardiomyopathies and myocardial disorders in Africa: present status and the way forward. Cardiovascular journal of Africa. 2012 ...
Myocardial infarction and stroke. Neurology. 1984 Nov;34(11):1403-9. PMID 6493488 Komrad MS. A defence of medical paternalism: ...
Goldberger AL (1991). Myocardial Infarction: Electrocardiographic Differential Diagnosis (4th ed.). St. Louis: Mosby-Year Book ... Henning, Robert J. (1976). "Myocardial Infarction: Electrocardiographic Differential Diagnosis". JAMA: The Journal of the ...
1995). "Saruplase in Myocardial Infarction". J. Thromb. Thrombolysis. 2 (3): 195-204. doi:10.1007/BF01062710. PMID 10608024. ... Moser M, Bode C (March 1999). "Pharmacology and clinical trial results of saruplase (scuPA) in acute myocardial infarction". ...
"Sleep Duration and Myocardial Infarction". Journal of the American College of Cardiology. 74 (10): 1304-1314. doi:10.1016/j. ... who slept less than 6 hours a day were associated with a 20 percent increase in the risk of developing myocardial infarction ( ...
He died of myocardial infarction. "Chess Scotland". www.chessscotland.com. "Chess Scotland". www.chessscotland.com. "Chess ...
A routine preventive dose is no longer recommended after a myocardial infarction as the overall benefit is not convincing. A ... Martí-Carvajal AJ, Simancas-Racines D, Anand V, Bangdiwala S (August 2015). "Prophylactic lidocaine for myocardial infarction ... for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available ...
If heart failure ensues after a myocardial infarction due to scarring and aneurysm formation, reconstructive surgery may be an ... Cooley DA, Collins HA, Morris GC, Chapman DW (May 1958). "Ventricular aneurysm after myocardial infarction; surgical excision ... March 2002). "Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction ... and it is specifically labelled for use in decompensated heart failure complicating acute myocardial infarction. While the ...
Diagram of a myocardial infarction. Aorta and coronary arteries at autopsy. The proximal portion of the RCA and its ostium can ...
Collins SD, Baffour R, Waksman R (2007). "Cell therapy in myocardial infarction". Cardiovasc Revasc Med. 8 (1): 43-51. doi: ... implications in cell-based myocardial therapy". Regen Med. 4 (5): 733-45. doi:10.2217/rme.09.43. PMID 19761398. Madeddu P (May ... protected the cells from an immunorespone for three weeks and also led to an improvement in the cardiac tissue post-infarction ...
Biyik, I.; Ergene, O. (January-February 2007). "Alcohol and acute myocardial infarction". J Int Med Res. 35 (1): 46-51. doi: ... blood pressure and vascular tone and is associated with embolic stroke and acute myocardial infarction. Due to these risks ... In individuals with an underlying cardiac disorder a binge on alcohol increases the risk of silent myocardial ischaemia as well ...
Efficacy of Myocardial Infarction Therapy. Marcel Dekker, New York, NY, 1999. Nash IS. Medical and health reporting in the news ...
Myocardial infarction, gangrene, and ischemic stroke are among the complications of severe arterial occlusion. A myocardial ... NSTEMI stands for 'Non-ST Elevation Myocardial Infarction', referencing the lack of ST-segment elevation in ECG traces. This is ... A comprehensive review to help distinguish ST elevation myocardial infarction from nonischemic etiologies of ST elevation". ... June 2019). "ST-segment elevation myocardial infarction". Nature Reviews. Disease Primers. 5 (1): 39. doi:10.1038/s41572-019- ...
Chung MJ, Brown DL (July 2018). "Diagnosis of acute myocardial infarction.". In Brown DL (ed.). Cardiac Intensive Care-E-Book. ... Myoglobin is typically released in the circulation as early as 1 h after myocardial infarction,... Myoglobin has poor clinical ... However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB, cardiac troponin, ECG, ... Myoglobin is not specific for myocardial necrosis, however, especially in the presence of skeletal muscle injury and renal ...
Prior to a myocardial infarction (MI or heart attack), plaque may accumulate in the coronary arteries, Some plaque formations ... Davies, M. J., & Thomas, A. C. (1985). Plaque fissuring-the cause of acute myocardial infarction, sudden ischaemic death, and ... 31: 75-82 Davies, M. J., & Thomas, A. C. (1985). Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic ... Thygesen, K., Alpert, J. S., & White, H. D. (2007). Universal definition of myocardial infarction. Journal of the American ...
She died of a myocardial infarction. Obituaries in the Performing Arts, 2015. 2016-03-30. ISBN 9780786476671. Obituary, emol. ...
These monocytes, upon moving to injured tissue (such as the heart after myocardial infarction), turn into dendritic cells and ... Release of neutrophils following myocardial infarction. Creation of red blood cells. While the bone marrow is the primary site ... leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ. Splenic infarction occurs when ... Splenic infarction is a condition in which blood flow supply to the spleen is compromised, ...
He died of a myocardial infarction. A Man for Burning (1962) - Don Vincenzo Extraconiugale (1964) - Padre di Renato (segment " ...
"Third universal definition of myocardial infarction". European Heart Journal. 33 (20): 2551-2567. doi:10.1093/eurheartj/ehs184 ... intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: ...
... though are increased with acute myocardial infarction.[7] A low number of ECFCs has been identified as a risk factor for infant ...
... death differs according to type of oral glucose-lowering therapy in patients with diabetes and a previous myocardial infarction ...
myocardial infarction[*] Lifatopam: Hoboken Cal(s): television actor[*], dramatan bioskopik[*], hidramatan[*], hikanitan, ...
Deaths from myocardial infarction. *Golden Globe Award winning actors. Hidden categories: *Articles with hCards ...
HDL, HDL2, and HDL3 subfractions, and the risk of acute myocardial infarction. A prospective population study in eastern ...
Side effects such as hypotension, myocardial infarction, congestive heart failure, cardiac fibrosis, pericardial effusion and ...
Women are significantly more likely to experience syncope as a presenting symptom of a myocardial infarction.[18] In general, ... "Sex differences in symptom presentation in acute myocardial infarction: A systematic review and meta-analysis". Heart & Lung. ... The most common cause in this category is fainting associated with an acute myocardial infarction or ischemic event. The faint ... history of myocardial infarction, ECG abnormalities, palpitations, signs of hemorrhage, syncope during exertion, and advanced ...
Deaths from myocardial infarction. Hidden categories: *CS1 maint: url-status. *CS1 Swedish-language sources (sv) ...
... nonfatal stroke or myocardial infarction) or cardiovascular mortality.[116] There is a long history of belief that topical ... "Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis". Nutrition, Metabolism ...
Deaths from myocardial infarction. *French singers. *French movie actors. *French television actors ...
Deaths from myocardial infarction. Hidden categories: *Articles with hCards. *Commons category link is on Wikidata ...
Gbigbọn ọpa to ngbe ẹjẹ kuro lati ọkan le ṣẹlẹ pẹlu myocardial infarction, aidun deedeti o tẹle, tabicardiac arrest.[3][5] Awọn ... Ṣugbọn a ti ri asopọ mọ dysrhythmia ati myocardial infarctionninu efinifirini ti a fun ni nipasẹ iṣan.[29] Abẹrẹ to nfun ni ni ...
"Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans ...
... excluding stroke and myocardial infarction).»։ Cochrane database of systematic reviews (Online) (3): CD003747։ PMID 19588346։ ...
併發症(英语:Myocardial infarction complications). *小時 *Hibernating myocardium(英语:Hibernating myocardium) ...
The Type of Oil Used for Cooking Is Associated with the Risk of Nonfatal Acute Myocardial Infarction in Costa Rica". Journal of ...
Law M, Wald N, Morris J (2003). "Lowering blood pressure to prevent myocardial infarction and stroke: a new preventive strategy ...
... from drug overdose or myocardial infarction). A permanent pacemaker may be placed in situations where the bradycardia is not ... that is myocardial ischemia or a heart attack[15] Approximately 180,000 to 250,000 people die suddenly of this cause every year ... so the myocardial cells are unable to activate the fast sodium channel, part of the impulse will arrive late and potentially be ... due to the infection's ability to cause myocardial injury.[11] Sudden cardiac death is the cause of about half of deaths due to ...
Daiths frae myocardial infarction. *Erse-American history. *Male short story writers. *Modrenist writers ...
Coronary artery spasm may occur with subsequent myocardial infarction, dysrhythmia, or cardiac arrest.[3][14] Those with ... Intravenous epinephrine, however, has been associated both with dysrhythmia and myocardial infarction.[8] Epinephrine ... and evidence of myocardial hypoperfusion.[41] Laboratory findings could detect increased levels of serum tryptase, increase in ...
Represenetatibong tanawin ng echocardiogrepiya mga apat na linggo pagkatapos ng isang myocardial infarction (MI), kanan bago ...
Deaths from myocardial infarction. *Italian footballers. *Sportspeople from Cardiff. *Sportspeople from Tuscany ...
... myocardial infarction]] atau [[embolisme pernapasan]].,ref name=C250,Cunha (2010). Pages 250-251.,/ref, ...
Temporay pacing may be done for very slow heartbeats, or bradycardia, from drug overdose or myocardial infarction. A pacemaker ...
An increase of mitochondrial AST in bloods is highly suggestive of tissue necrosis in myocardial infarction and chronic liver ... Other causes of elevated GGT are: diabetes mellitus, acute pancreatitis, myocardial infarction, anorexia nervosa, Guillain- ... "Cardiac troponin T and I and creatine kinase-MB as markers of myocardial injury and predictors of outcome following ...
Deaths from myocardial infarction. *Disease-related deaths in Nigeria. *Politicians from London ...
Myocardial infarction. *Unstable angina. Sequelae. *hours *Hibernating myocardium. *Myocardial stunning. *days *Myocardial ...
myocardial infarction[*] Cal(s): futaglöpädan[*], association football manager[*], hidramatan[*] Tatät(s): Largäntän ...
The FDA approved the CardiAssistTM ECP system for the treatment of angina, acute myocardial infarction and cardiogenic shock ... acute myocardial infarction, cardiogenic shock, and congestive heart failure.[2] Studies have found EECP to be beneficial for ... "Does Enhanced External Counterpulsation (EECP) Significantly Affect Myocardial Perfusion?: A Systematic Review & Meta-Analysis ...
"Lowering blood pressure to prevent myocardial infarction and stroke: a new preventive strategy" (PDF). Health Technol Assess. 7 ...
Over a million people in the U.S. have a heart attack each year. Learn the symptoms and get help quickly to prevent permanent heart damage and death.
Acute Myocardial Infarction NOMS PMRs for Transportation Sector. Data from 1999, 2003-2004, 2007-2010. Suggested Citation : ...
Acute Myocardial Infarction NOMS PMRs for Public Safety Sector. Data from 1999, 2003-2004, 2007-2010. Suggested Citation : ...
Sara, K. (‎1997)‎. [‎Myocardial infarction in district hospitals]‎. EMHJ - Eastern Mediterranean Health Journal, 3 (‎1)‎, 176- ...
Thrombolytic Therapy for Acute Myocardial Infarction. Myocardial infarction (MI) is a leading cause of morbidity and mortality ... What are guidelines for thrombolytic therapy for myocardial infarction (MI)?. How is myocardial infarction (MI) following early ... What is the prevalence of myocardial infarction (MI)?. When is thrombolytic therapy indicated in the treatment of myocardial ... for the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment-Thrombolysis In Myocardial Infarction ...
Myocardial infarction, commonly known as a heart attack, is the irreversible necrosis of heart muscle secondary to prolonged ... encoded search term (Myocardial Infarction) and Myocardial Infarction What to Read Next on Medscape ... Obtain an ECG immediately if myocardial infarction is considered or suspected. In patients with inferior myocardial infarction ... Inflammatory Drugs and Impact on Risk of Death and Recurrent Myocardial Infarction in Patients With Prior Myocardial Infarction ...
Unknown author (‎1989)‎. Vasodilator therapy following myocardial infarction. WHO drug information 1989 ; 3(‎4)‎ : 169-170 ...
... acute myocardial infarction - Featured Topics from the National Center for Health Statistics ... Acute myocardial infarction (I21-I22) Read More ,. Posted on February 15, 2017. by NCHS. Categories acute myocardial infarction ... Categories acute myocardial infarction, Coronary atherosclerosis, heart attack, Hospital Discharge Survey, hospitalization, ... This week it highlights hospitalizations rates for coronary atherosclerosis and acute myocardial infarction for the period 1996 ...
Many risk factors of myocardial infarction are shared with coronary artery disease, the primary cause of myocardial infarction ... it may be classified as an ST elevation myocardial infarction (STEMI) or Non-ST elevation myocardial infarction (NSTEMI) based ... and Treatment Trends of Myocardial Infarction". In Morrow DA (ed.). Myocardial Infarction: A Companion to Braunwalds Heart ... "Heart Failure and Cardiogenic Shock After Myocardial Infarction". In Morrow DA (ed.). Myocardial Infarction: A Companion to ...
How much do you know about the prevention of repeat myocardial infarctions? Test your knowledge with this quick quiz. ... Fast Five Quiz: Are You Prepared to Confront a Myocardial Infarction? * Fast Five Quiz: Prevention of Repeat Myocardial ... Fast Five Quiz: Prevention of Repeat Myocardial Infarction - Medscape - Dec 14, 2020. ...
Womens early warning symptoms of acute myocardial infarction Circulation. 2003 Nov 25;108(21):2619-23. doi: 10.1161/01.CIR. ... Using the McSweeney Acute and Prodromal Myocardial Infarction Symptom Survey, we surveyed them 4 to 6 months after discharge, ... Background: Data remain sparse on womens prodromal symptoms before acute myocardial infarction (AMI). This study describes ...
Purchase Myocardial Infarction: A Companion to Braunwalds Heart Disease - 1st Edition. Print Book & E-Book. ISBN 9780323359436 ... Myocardial Infarction: A Companion to Braunwalds Heart Disease. Preview. Preview. - Myocardial Infarction: A Companion to ... 22 Stem Cell Therapy in Patients with Myocardial Infarction. 23 Recurrent Ischemia and Recurrent Myocardial Infarction: ... 25 Heart Failure and Cardiogenic Shock After Myocardial Infarction. 26 Mechanical Complications of Myocardial Infarction. 27 ...
... Share, Forecast 2020 to 2026 - published on openPR.com ... Myocardial Infarction Market By Type. • Non-ST-elevation myocardial infarction (NSTEMI). • ST-elevation myocardial infarction ( ... the market is segmented into ST-elevation myocardial infarction (STEMI) heart attacks, non-ST elevation myocardial infarction ( ... LAMEA myocardial infarction market is estimated to grow at the fastest CAGR of around 5.2% during the forecast period. The ...
Age at myocardial infarction. The mean age at myocardial infarction was 61.2 (SD 13.4) years in the whole population. The mean ... As myocardial infarction is the principal cause of death in the community, estimates of myocardial infarction incidence rate by ... Myocardial infarction incidence rate. Crude and age-standardized myocardial infarction incidence rates in the countrys ... where the crude and standardized incidences of myocardial infarction with ST-elevation myocardial infarction were 92.8 and ...
Myocardial infarction is more commonly known as a heart attack. See the article on heart disease for more information. ... Retrieved from "https://www.SNPedia.com/index.php?title=Myocardial_infarction&oldid=42522" ...
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Thrombolytic Therapy for Acute Myocardial Infarction. Myocardial infarction (MI) is a leading cause of morbidity and mortality ... What are guidelines for thrombolytic therapy for myocardial infarction (MI)?. How is myocardial infarction (MI) following early ... What is the prevalence of myocardial infarction (MI)?. When is thrombolytic therapy indicated in the treatment of myocardial ... for the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment-Thrombolysis In Myocardial Infarction ...
Chocolate consumption is associated with lower risk of myocardial infarction and ischaemic heart disease. ... Diseases : Heart Disease: Ischemic : CK(180) : AC(26), Myocardial Infarction : CK(1563) : AC(315), Myocardial Infarction: ... Myocardial infarction (MI) cases were ascertained through linkage with the Swedish National Patient and Cause of Death ... Chocolate consumption is associated with lower risk of myocardial infarction and ischaemic heart disease. - GreenMedInfo ...
No prior myocardial infarction Study Requirements. In this study, subjects will be randomized to receive a subcutaneous ... The MADIT S-ICD trial is designed to evaluate if subjects with a prior myocardial infarction, diabetes mellitus and a ...
... Jackevicius CA, Alter D, Cox J, Daly P, Goodman S, Filate W, ... Background - Therapy for management of acute myocardial infarction (AMI) varies according to patient, prescriber and ...
... for acute myocardial infarction (AMI).,i, Background,/i,. It is unknown whether the timing of VT/VF occurrence affects the ... Impact of Late Ventricular Arrhythmias on Cardiac Mortality in Patients with Acute Myocardial Infarction. Takuma Takada. ,1Koki ... R. W. F. Campbell, "Arrhythmias," in Management of Acute Myocardial Infarction, D. Julian and E. Brauwnwald, Eds., pp. 223-240 ... 100%, p= 0.34), the ratio of ST elevated myocardial infarction (92% vs. 83%, p=0.24), and Killip class (p= 0.63) did not differ ...
Myocardial Infarction Report by Material, Application, and Geography Global Forecast to 2021 is a professional and in-depth ... Part I Myocardial Infarction Industry Overview. Chapter One Myocardial Infarction Industry Overview. 1.1 Myocardial Infarction ... 17.1 Myocardial Infarction Market Analysis. 17.2 Myocardial Infarction Project SWOT Analysis. 17.3 Myocardial Infarction New ... 2.) the Asia Myocardial Infarction Market; 3.) the North American Myocardial Infarction Market; 4.) the European Myocardial ...
The Age-Specific Incidence of Admission to the Intensive Care Unit for Acute Myocardial Infarction in Antigua and Barbuda Issue ... Read more about The Age-Specific Incidence of Admission to the Intensive Care Unit for Acute Myocardial Infarction in Antigua ... In this study, the acute myocardial infarction (AMI) model was established after injecting A20 plasmid into the rats, the ... Objectives: The goal of this study is to identify co-morbidities associated with acute myocardial infarction in Tobago. ...
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. The highest risk of fatality occurs ... Mythili, S., Malathi, N.Diagnostic markers of acute myocardial infarction (Review). Biomedical Reports 3, no. 6 (2015): 743- ... Mythili S and Mythili S: Diagnostic markers of acute myocardial infarction (Review). Biomed Rep 3: 743-748, 2015 ... Mythili, S., Malathi, N.Diagnostic markers of acute myocardial infarction (Review). Biomedical Reports 3.6 (2015): 743-748. ...
Q. What are the cutting-edge treatments for acute myocardial infarctions?. A. The treatment of choice for patients having a ...
Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death. JAMA. 2008;299(19):2304-2312. ... Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death. ... Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death-Reply. JAMA 2008;300:1298-9. ...
Non-ST-elevation myocardial infarction (NSTEMI) is a type of heart attack involving a partly blocked coronary artery that ... Non-ST-elevation myocardial infarction (NSTEMI) is a type of involving partial blockage of one of the coronary arteries, ...
2018, July 10). What is a Heart Attack , How to Prevent Heart Attacks - Myocardial Infarction Smoking. Medindia. Retrieved on ... myocardial infarction. can occur much in advance (sometimes a month or even earlier than the actual heart attack). Of the 515 ... Studies on the prevention of heart attacks or myocardial infarction is a top priority for many research projects worldwide ... Other names for heart attack include acute myocardial infarction, coronary thrombosis, and coronary ... ...
Older individuals with a weekday bedtime later than midnight were associated with a greater risk of myocardial infarction. No ... Older individuals with a weekday bedtime later than midnight were associated with a greater risk of myocardial infarction. No ... Sleeping late increases the risk of myocardial infarction in the middle-aged and older populations. Front Cardiovasc Med. ... A bedtime later than midnight on weekdays may significantly increase the risk of myocardial infarction (MI), according to study ...
  • Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. (spandidos-publications.com)
  • The age and sex corrected mortality rates for the combined group of men and women show that those who stopped smoking after their infarction have 55% of the mortality of those who continued to smoke (P less than 0.05). (bmj.com)
  • The combination of abciximab in full doses and reteplase in half doses did not significantly reduce the rate of mortality at 30 days in patients with acute ST-segment elevation myocardial infarction (MI) when compared with reteplase in full doses in the Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO V) trial. (ccjm.org)
  • Reflecting the dramatically improved prognosis for these patients, the book concentrates on rehabilitation programmes designed to return patients to a normal life while reducing the likelihood of recurrent infarction or mortality from cardiovascular disease. (who.int)
  • AIMS: We examine whether inclusion of artificial intelligence (AI)-enabled retinal vasculometry (RV) improves existing risk algorithms for incident stroke, myocardial infarction (MI) and circulatory mortality. (ucl.ac.uk)
  • We calculated pooled relative risks using a fixed-effect meta-analysis assessing the impact of adjunctive adenosine therapy on major clinical endpoint including all-cause mortality, non-fatal myocardial infarction, and heart failure. (uea.ac.uk)
  • Pay for performance had no effect on the cumulative incidence of stroke, myocardial infarction, renal failure, heart failure, or all cause mortality in both treatment experienced and newly treated subgroups. (bmj.com)
  • Researchers in the study "Green tea and coffee consumption and all-cause mortality among persons with and without stroke or myocardial infarction" sought to determine the effects of green tea and coffee consumption after surviving a stroke or heart attack . (heart.org)
  • In-hospital mortality of COVID-19 patients hospitalized with ST-segment elevation myocardial infarction: A meta-analysis. (nih.gov)
  • Differences in late cardiovascular mortality following acute myocardial infarction in three major Asian ethnic groups. (duke-nus.edu.sg)
  • Arterial thrombosis is directly related to atherosclerosis and represents the leading cause of mortality in the world, commonly manifesting as acute myo- cardial infarction (AMI), cerebrovascular accident (CVA)/transient ischemic attack (TIA), and peripheral arterial obstructive disease(1,3). (bvsalud.org)
  • The American College of Cardiology/American Heart Association (ACC/AHA) guidelines on unstable angina/NSTEMI recommend that in patients with suspected myocardial infarction, cardiac biomarkers should be measured at presentation. (medscape.com)
  • Remeasuring cardiac enzyme levels at regular intervals for the first 24 hours is a reasonable approach to improving the sensitivity of detection of myocardial necrosis, and the degree of positivity can be important for prognostication. (medscape.com)
  • Ventricular tachycardia (VT) and ventricular fibrillation (VF) are fatal arrhythmias that could occur in cardiac collapse and are major complications of acute myocardial infarction (AMI) [ 1 , 2 ]. (hindawi.com)
  • The diagnosis of AMI definitions showed as typical lasting chest pain, increase of cardiac enzymes above the normal range, and onset of ST-T changes compatible with myocardial ischemia (ST segment elevation or depression, T-wave inversion) or abnormal Q waves. (hindawi.com)
  • How renal function influences post-acute myocardial infarction (AMI) cardiac remodeling and outcomes remains unclear. (medsci.org)
  • Acute myocardial infarction should be excluded using cardiac markers in patients presenting to the emergency department with cocaine related chest pain. (bmj.com)
  • TT-10-loaded nanoparticles promote cardiomyocyte proliferation and cardiac repair in a mouse model of myocardial infarction. (bvsalud.org)
  • Acute myocardial infarction (MI), commonly known as a heart attack, is a condition characterized by ischemic injury and necrosis of the cardiac muscle. (medscape.com)
  • Between 1990 and 2001, 250 patients were admitted to rule out myocardial infarction in Antigua, 55% were confirmed. (uwi.edu)
  • Background - Therapy for management of acute myocardial infarction (AMI) varies according to patient, prescriber and geographical characteristics. (ices.on.ca)
  • The first goal for healthcare professionals in management of acute myocardial infarction (MI) is to diagnose the condition in a very rapid manner. (onteenstoday.com)
  • The most common co-morbidities associated with acute myocardial infarction in Tobago are dyslipidaemia, hypertension and diabetes mellitus. (uwi.edu)
  • The goal of this study is to identify co-morbidities associated with acute myocardial infarction in Tobago. (uwi.edu)
  • and CD8 + T cells secreting IL-17 and Tregs is associated with acute myocardial infarction. (scirp.org)
  • Based on type, the market is segmented into ST-elevation myocardial infarction (STEMI) heart attacks, non-ST elevation myocardial infarction (NSTEMI) heart attacks, and silent heart attacks. (openpr.com)
  • Non-ST-elevation myocardial infarction (NSTEMI) is a type of involving partial blockage of one of the coronary arteries, causing reduced flow of oxygen-rich blood to the heart muscle. (uky.edu)
  • STEMI' is an acronym for ST-elevation myocardial infarctions. (colorado.gov)
  • Such poisoning may present with ST elevation in the electrocardiogram and symptoms mimicking acute myocardial infarction. (hkmj.org)
  • EMplify January 2021Evaluation and Management of ST-Segment Elevation Myocardial Infarction in the Emergency DepartmentAuthorsMarshall Frank, DO, MPH, FACEPCarson Sanders, BS, NRP, CCEMT-PBryan P. Berry, MD, BCEM, FACEP TopicsEpidemiologyPathophysiologyPrehospital careEmergency Dept Evaluation* History* PhysicalImagingLabsElectrocardiogram* aVR* Posterior Leads* LBBB* Serial ECGs* Reciprocal Changes* Pericarditis vs STEMITreatment* Oxygen* Opioids* Antiplatelet Agents* Nitroglycerin* Beta Blockers* ReperfusionPCIThrombolyticsDysrhythmias* AnticoagulantsTransfersSpecial Circumstances* Gender* Age* CocaineHave questions or comments on the podcast? (apple.com)
  • Most acute myocardial infarction patients will present with ST elevation or an abnormal ECG. (bmj.com)
  • Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction: --Part II. (aafp.org)
  • This is part II of a two-part article on unstable angina and non-ST-segment elevation myocardial infarction. (aafp.org)
  • The updated guideline from the American College of Cardiology and the American Heart Association (ACC/AHA) 1 , 2 divides the assessment and treatment of patients with unstable angina and non-ST-segment elevation myocardial infarction (UA/NSTEMI) into four components. (aafp.org)
  • Background: Adenosine administered as an adjunct to reperfusion can reduce coronary no-reflow and limit myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients. (uea.ac.uk)
  • Methods and Results: Intracellular expression of interferon-γ Interleukin (IL)-4, IL-17, IL-10 and Foxp3 were determined in CD4 + and CD8 + T cells using flow cytometry in patients with ST elevated myocardial infarction (STEMI) (N = 79) and controls (N = 80). (scirp.org)
  • For stroke and myocardial infarction survivors green tea consumption is associated with improved prognosis. (thecardiologyadvisor.com)
  • HealthDay News - For stroke and myocardial infarction (MI) survivors, green tea consumption is associated with improved prognosis, according to a study published online Feb. 4 in Stroke . (thecardiologyadvisor.com)
  • Those events include death, myocardial infarction, stroke, heart failure and pulmonary embolism in each group. (acc.org)
  • In conclusion, evaluation of immunohistochemical expression of C9 appears to be a highly sensitive and specific marker of early myocardial infarction, useful in forensic medicine if survival is more than 1 h after the beginning of myocyte damage. (astm.org)
  • Yes: An anterior myocardial infarction is usually caused by a sudden blockage of one of the three primary heart arteries, the lad. (onteenstoday.com)
  • Apical left ventricular (LV) dyskinesis (ventricular aneurysm) after an anterior myocardial infarction. (medscape.com)
  • However, the specific predictive biomarkers and candidate therapeutic targets for post-infarction HF have not been fully established. (frontiersin.org)
  • Specifically, the blue module was found to be the most significantly related to the development of post-infarction HF. (frontiersin.org)
  • It is not only considered to be the gold standard for assessment of myocardial function, but also for the detection of myocardial necrosis and fibrosis. (eur.nl)
  • Acute myocardial infarction (AMI) is characterized by myocardial necrosis resulting from exposure to prolonged ischemia after occlusion of a coronary artery ( Anderson and Morrow, 2017 ). (frontiersin.org)
  • NECROSIS del MIOCARDIO causada por una obstrucción en el suministro de sangre al corazón (CIRCULACIÓN CORONARIA). (bvsalud.org)
  • One crucial parameter to evaluate the state of the heart after myocardial infarction (MI) is the viability of the myocardial segment, i.e., if the segment recovers its functionality upon revascularization. (mdpi.com)
  • Recent trials employing modern antiplatelet and antithrombotic therapies and catheterization techniques have included the FRagmin and Fast Revascularization during InStability in Coronary artery disease II (FRISC II) study 4 and the Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy Thrombolysis in Myocardial Infarction 18 (TACTICS-TIMI 18) trial. (aafp.org)
  • In addition, cardiovascular MRI provides clinically relevant information on stunning, microvascular obstruction, transmural extent of the infarction, hemorrhage and postmyocardial infarction complications such as thrombus, Dressler syndrome and aneuryms. (eur.nl)
  • Among patients hospitalized for acute myocardial infarction (AMI), renal impairment is also an important predictor of cardiovascular complications, including heart failure, arrhythmia and coronary arterial restenosis [ 1 , 4 ]. (medsci.org)
  • Although the immediate priority in managing acute myocardial infarction is thrombolysis and reperfusion of the myocardium, a variety of other drug therapies such as heparin, β-adrenoceptor blockers, magnesium and insulin might also be considered in the early hours. (onteenstoday.com)
  • Cocaine and chest pain: clinical features and outcome of patients hospitalized to rule out myocardial infarction. (bmj.com)
  • Life saving measures for acute myocardial infarction include reperfusion therapy. (uwi.edu)
  • Her past medical history was significant for peripheral vascular disease (PVD), diabetes, myocardial infarction with percutaneous intervention, and ischemic cardiomyopathy. (hindawi.com)
  • 0000-0002-9068-7189 ischemic attack, acute myocardial infarction, and pulmonary thromboembolism. (bvsalud.org)
  • Cardiovascular risk factors among children of men with premature myocardial infarction. (cdc.gov)
  • Get the tools and knowledge you need for effective diagnosis, evaluation, and management of patients with acute myocardial infarction. (elsevier.com)
  • This rising hypertension among patients in South Africa and UAE is expected to boost the adoption of diagnosis and treatment procedures for myocardial infarction, to reduce the possibility of occurrence of severe conditions, including heart attack. (openpr.com)
  • Before the first 12 hours, diagnosis of early myocardial infarctions is always difficult for forensic pathologists. (astm.org)
  • The age-standardized myocardial infarction incidence rate was 73.3 per 100 000 in the whole country (95% CI: 72.3%-74.3%) and varied significantly from 24.5 to 152.5 per 100 000 across the 31 provinces. (who.int)
  • Insomnia is associated with increased risk of cardiovascular disease (CVD) and may play a role in the increased incidence of myocardial infarctions (MIs) seen among PLWH. (natap.org)
  • A short cut review was carried out to establish the incidence of acute myocardial infarction in patients presenting as emergencies with post-cocaine chest pain. (bmj.com)
  • The incidence of acute myocardial infarction in cocaine associated chest pain is small but significant. (bmj.com)
  • The development of heart failure (HF) remains a common complication following an acute myocardial infarction (AMI), and is associated with substantial adverse outcomes. (frontiersin.org)
  • Long-term trends in short-term outcomes in acute myocardial infarction. (umassmed.edu)
  • The MADIT S-ICD trial is designed to evaluate if subjects with a prior myocardial infarction, diabetes mellitus and a relatively preserved ejection fraction of 36-50% will have a survival benefit from receiving a subcutaneous implantable cardioverter defibrillator (S-ICD) when compared to those receiving conventional medical therapy. (tuftsmedicalcenter.org)
  • This week it highlights hospitalizations rates for coronary atherosclerosis and acute myocardial infarction for the period 1996-2005. (cdc.gov)
  • 4 Furthermore, increased arterial stiffness leads to an increase in pulse pressure, which is a highly significant predictor of myocardial infarction and cardiovascular death. (bmj.com)
  • This study investigated the relationship between the timing of ventricular tachycardia or ventricular fibrillation (VT or VF) and prognosis in patients undergoing primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). (hindawi.com)
  • Fast Five Quiz: Prevention of Repeat Myocardial Infarction - Medscape - Dec 14, 2020. (medscape.com)
  • Cite this: Ventricular Tachycardia During Acute Myocardial Infarction - Medscape - Mar 01, 2007. (medscape.com)
  • Fast Five Quiz: Myocardial Infarction Clinical Keys - Medscape - Nov 13, 2020. (medscape.com)
  • Data remain sparse on women's prodromal symptoms before acute myocardial infarction (AMI). (nih.gov)
  • Using the McSweeney Acute and Prodromal Myocardial Infarction Symptom Survey, we surveyed them 4 to 6 months after discharge, asking about symptoms, comorbidities, and demographic characteristics. (nih.gov)
  • Symptoms, thoughts, and environmental factors in suspected acute myocardial infarction. (arctichealth.org)
  • OBJECTIVE: To increase our understanding of patients' reactions and behavior at onset of symptoms of myocardial infarction. (arctichealth.org)
  • PROCEDURE: During a 5-month period a questionnaire focusing on symptoms, thoughts, and environmental factors at onset of symptoms was administered to all patients admitted to the coronary care unit at Sahlgrenska Hospital in Göteborg, Sweden, because of suspected acute myocardial infarction. (arctichealth.org)
  • The present study was undertaken to check the lipid profile in patients of acute myocardial infarction withchronic diabetes and to evaluate the variations in various lipid levels in different age, gender and in patientswith different habits of diet, smoking and alcohol consumption. (who.int)
  • The aim of this study was to provide an overview of the risk factors for acute myocardial infarction in patients attending Tripoli Medical Centre, Libya. (who.int)
  • Chocolate consumption is associated with lower risk of myocardial infarction and ischaemic heart disease. (greenmedinfo.com)
  • Sidney M. Wolfe, MD. Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death. (citizen.org)
  • Older individuals with a weekday bedtime later than midnight were associated with a greater risk of myocardial infarction. (ajmc.com)
  • A bedtime later than midnight on weekdays may significantly increase the risk of myocardial infarction (MI), according to study findings published in Frontiers in Cardiovascular Medicine . (ajmc.com)
  • Sleeping late increases the risk of myocardial infarction in the middle-aged and older populations. (ajmc.com)
  • These results suggest that smoking is not merely a 'risk factor' for myocardial infarction but is also a causal factor whose effects can be avoided by both men and women after an initial myocardial infarction. (bmj.com)
  • OBJECTIVE: To determine the risk for incident myocardial infarction (MI) in women exposed to modern formulations of oral contraceptives (OCs). (healthpartners.com)
  • Associations between childhood maltreatment and risk of myocardial infarction in adulthood: Results from the National Epidemiologic Survey on alcohol and Related Conditions. (semanticscholar.org)
  • Those patients presenting with normal findings, and a normal ECG have a low but not absent acute myocardial infarction risk. (bmj.com)
  • 2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)
  • Acute myocardial infarction and chest pain syndromes after cocaine use. (bmj.com)
  • ABSTRACT Population-based data on myocardial infarction rates in the Islamic Republic of Iran have not been reported on a national or provincial scale. (who.int)
  • Myocardial Infarction Report by Material, Application, and Geography Global Forecast to 2021 is a professional and in-depth research report on the worlds major regional market conditions, focusing on the main regions (North America, Europe and Asia-Pacific) and the main countries (United States, Germany, united Kingdom, Japan, South Korea and China). (aarkstore.com)
  • [ 2 ] In 1958, streptokinase was first used in patients with acute myocardial infarction (AMI), and this changed the focus of treatment. (medscape.com)
  • Treatment of severe myocardial infarction can be quite expensive. (bajajfinservmarkets.in)
  • What is the first step in treatment of myocardial infarction? (onteenstoday.com)
  • A heart attack, also called a myocardial infarction, can be fatal, but treatment has improved dramatically over the years. (onteenstoday.com)
  • What is the treatment for a myocardial infarction? (onteenstoday.com)
  • Health care providers typically use a combination of medication and mechanical intervention as treatment for a myocardial infarction, more commonly referred to as a heart attack. (onteenstoday.com)
  • Myocardial infarction treatment Home Programme : General exercises 1 half yard grasp standing-one leg swinging forward and backwards then repeat with other leg. (onteenstoday.com)
  • What is treatment for anterior infarction? (onteenstoday.com)
  • Thus, NP-mediated delivery appears to enhance both the potency and durability of TT-10 treatment for myocardial repair. (bvsalud.org)
  • The execution of a appropriate odontological surgical treatment for patients with Myocardial Infarction has been based in established protocols for important works in world wide literature during the sixty's and seventy's decade, established with a minimum of six months before the noncardiac surgery. (bvsalud.org)
  • Myocardial Infarction: A Companion to Braunwald's Heart Disease, by David A. Morrow, MD, is a comprehensive, hands-on resource that provides practical guidance from a name you trust. (elsevier.com)
  • Studies on the prevention of heart attacks or myocardial infarction is a top priority for many research projects worldwide because cardiovascular disease or heart disease is still the leading cause of death about 30% of deaths all over the world - despite giant strides being made in the medical field. (medindia.net)
  • Assistência cirúrgico-odontológica a pacientes com história de infarto do miocárdio Surgical-odontologic assessment to patients with myocardial infarction history . (bvsalud.org)
  • Myocardial infarction is more commonly known as a heart attack . (snpedia.com)
  • Myocardial infarction or commonly known as heart attack is a serious medical condition which occurs when there is not enough blood supply to the heart muscles. (bajajfinservmarkets.in)