Mucoepidermoid Tumor
Carcinoma, Mucoepidermoid
Salivary Glands, Minor
Adenolymphoma
Tracheal Neoplasms
Adenoma, Pleomorphic
Carcinoma, Adenoid Cystic
Carcinoma, Acinar Cell
Encyclopedias as Topic
Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy. (1/1)
(+info)A mucoepidermoid tumor is a type of salivary gland neoplasm (abnormal growth) that can occur in the major or minor salivary glands. These tumors are characterized by the presence of mucus-secreting cells, epidermoid cells (which resemble skin cells), and intermediate cells.
Mucoepidermoid tumors are classified into three grades based on their histological features: low grade, intermediate grade, and high grade. Low-grade mucoepidermoid tumors tend to grow slowly and have a better prognosis compared to higher-grade tumors, which are more aggressive and have a higher risk of recurrence and metastasis (spread to other parts of the body).
Treatment for mucoepidermoid tumors typically involves surgical excision. The extent of surgery depends on the location, size, and grade of the tumor. Radiation therapy may also be recommended in some cases, particularly for high-grade tumors or when there is a high risk of residual tumor after surgery.
Mucoepidermoid carcinoma is a type of cancer that develops in the salivary glands or, less commonly, in other areas such as the lungs or skin. It is called "mucoepidermoid" because it contains two types of cells: mucus-secreting cells and squamous (or epidermoid) cells.
Mucoepidermoid carcinomas can vary in their behavior, ranging from low-grade tumors that grow slowly and rarely spread to other parts of the body, to high-grade tumors that are aggressive and can metastasize. The treatment and prognosis for mucoepidermoid carcinoma depend on several factors, including the grade and stage of the tumor, as well as the patient's overall health.
It is important to note that while I strive to provide accurate and up-to-date information, this definition may not capture all the nuances of this medical condition. Therefore, it is always best to consult with a healthcare professional for medical advice.
Salivary gland neoplasms refer to abnormal growths or tumors that develop in the salivary glands. These glands are responsible for producing saliva, which helps in digestion, lubrication of food and maintaining oral health. Salivary gland neoplasms can be benign (non-cancerous) or malignant (cancerous).
Benign neoplasms are slow-growing and typically do not spread to other parts of the body. They may cause symptoms such as swelling, painless lumps, or difficulty swallowing if they grow large enough to put pressure on surrounding tissues.
Malignant neoplasms, on the other hand, can be aggressive and have the potential to invade nearby structures and metastasize (spread) to distant organs. Symptoms of malignant salivary gland neoplasms may include rapid growth, pain, numbness, or paralysis of facial nerves.
Salivary gland neoplasms can occur in any of the major salivary glands (parotid, submandibular, and sublingual glands) or in the minor salivary glands located throughout the mouth and throat. The exact cause of these neoplasms is not fully understood, but risk factors may include exposure to radiation, certain viral infections, and genetic predisposition.
Minor salivary glands are numerous small exocrine glands that produce saliva and are distributed throughout the oral cavity, nasal cavity, pharynx, larynx, and paranasal sinuses. They are classified as "minor" due to their smaller size compared to the three pairs of major salivary glands (parotid, submandibular, and sublingual). The minor salivary glands are primarily mucous glands, although some contain serous cells. They are responsible for producing approximately 5-10% of the total saliva in the mouth. These glands help moisten the oral cavity, protect the mucosal lining, and facilitate speaking, chewing, and swallowing.
Parotid neoplasms refer to abnormal growths or tumors in the parotid gland, which is the largest of the salivary glands and is located in front of the ear and extends down the neck. These neoplasms can be benign (non-cancerous) or malignant (cancerous).
Benign parotid neoplasms are typically slow-growing, painless masses that may cause facial asymmetry or difficulty in chewing or swallowing if they become large enough to compress surrounding structures. The most common type of benign parotid tumor is a pleomorphic adenoma.
Malignant parotid neoplasms, on the other hand, are more aggressive and can invade nearby tissues and spread to other parts of the body. They may present as rapidly growing masses that are firm or fixed to surrounding structures. Common types of malignant parotid tumors include mucoepidermoid carcinoma, adenoid cystic carcinoma, and squamous cell carcinoma.
The diagnosis of parotid neoplasms typically involves a thorough clinical evaluation, imaging studies such as CT or MRI scans, and fine-needle aspiration biopsy (FNAB) to determine the nature of the tumor. Treatment options depend on the type, size, and location of the neoplasm but may include surgical excision, radiation therapy, and chemotherapy.
Adenolymphoma is a rare, benign tumor that arises from the lymphoid tissue found in glandular structures, such as the salivary glands. It is also known as Warthin's tumor or cystic papillary adenolymphoma.
The tumor is composed of multiple cyst-like spaces lined by columnar epithelial cells and surrounded by lymphoid tissue, which may contain lymphocytes, plasma cells, and occasionally, germinal centers. The etiology of adenolymphoma is unclear, but it has been associated with smoking and genetic factors.
Adenolymphomas are typically slow-growing and painless, although they can cause discomfort or facial asymmetry if they become large enough. They are usually diagnosed through imaging studies such as ultrasound, CT scan, or MRI, followed by a biopsy to confirm the diagnosis.
Treatment of adenolymphoma typically involves surgical excision, which is usually curative. Recurrence after surgery is rare, but long-term follow-up is recommended due to the potential for malignant transformation into squamous cell carcinoma or other malignancies.
Tracheal neoplasms refer to abnormal growths or tumors in the trachea, which is the windpipe that carries air from the nose and throat to the lungs. These growths can be benign (non-cancerous) or malignant (cancerous). Malignant tracheal neoplasms are relatively rare and can be primary (originating in the trachea) or secondary (spreading from another part of the body, such as lung cancer). Primary tracheal cancers can be squamous cell carcinoma, adenoid cystic carcinoma, mucoepidermoid carcinoma, or sarcomas. Symptoms may include cough, difficulty breathing, wheezing, or chest pain. Treatment options depend on the type, size, and location of the neoplasm and can include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
A pleomorphic adenoma is a type of benign (non-cancerous) tumor that typically develops in the salivary glands, although they can also occur in other areas such as the nasopharynx and skin. "Pleomorphic" refers to the diverse appearance of the cells within the tumor, which can vary in size, shape, and arrangement.
Pleomorphic adenomas are composed of a mixture of epithelial and mesenchymal cells, which can form glandular structures, squamous (scale-like) cells, and areas that resemble cartilage or bone. These tumors tend to grow slowly and usually do not spread to other parts of the body.
While pleomorphic adenomas are generally not dangerous, they can cause problems if they become large enough to press on surrounding tissues or structures. In some cases, these tumors may also undergo malignant transformation, leading to a cancerous growth known as carcinoma ex pleomorphic adenoma. Surgical removal is the standard treatment for pleomorphic adenomas, and the prognosis is generally good with proper management.
Adenoid cystic carcinoma (AdCC) is a rare type of cancer that can occur in various glands and tissues of the body, most commonly in the salivary glands. AdCC is characterized by its slow growth and tendency to spread along nerves. It typically forms solid, cystic, or mixed tumors with distinct histological features, including epithelial cells arranged in tubular, cribriform, or solid patterns.
The term "carcinoma" refers to a malignant tumor originating from the epithelial cells lining various organs and glands. In this case, adenoid cystic carcinoma is a specific type of carcinoma that arises in the salivary glands or other glandular tissues.
The primary treatment options for AdCC include surgical resection, radiation therapy, and sometimes chemotherapy. Despite its slow growth, adenoid cystic carcinoma has a propensity to recur locally and metastasize to distant sites such as the lungs, bones, and liver. Long-term follow-up is essential due to the risk of late recurrences.
Carcinoma, acinar cell is a type of pancreatic cancer that originates in the acinar cells of the pancreas. The acinar cells are responsible for producing digestive enzymes. This type of cancer is relatively rare and accounts for less than 5% of all pancreatic cancers. It typically presents with symptoms such as abdominal pain, weight loss, and jaundice. Treatment options may include surgery, chemotherapy, and radiation therapy.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Mucus is a viscous, slippery secretion produced by the mucous membranes that line various body cavities such as the respiratory and gastrointestinal tracts. It serves to lubricate and protect these surfaces from damage, infection, and foreign particles. Mucus contains water, proteins, salts, and other substances, including antibodies, enzymes, and glycoproteins called mucins that give it its characteristic gel-like consistency.
In the respiratory system, mucus traps inhaled particles such as dust, allergens, and pathogens, preventing them from reaching the lungs. The cilia, tiny hair-like structures lining the airways, move the mucus upward toward the throat, where it can be swallowed or expelled through coughing or sneezing. In the gastrointestinal tract, mucus helps protect the lining of the stomach and intestines from digestive enzymes and other harmful substances.
Excessive production of mucus can occur in various medical conditions such as allergies, respiratory infections, chronic lung diseases, and gastrointestinal disorders, leading to symptoms such as coughing, wheezing, nasal congestion, and diarrhea.
Mucoepidermoid carcinoma
Adenoid cystic carcinoma
CRTC1
MAML2
Parotid gland
Ceruminous gland
Sebaceous lymphadenoma
Salivary gland tumour
Hidradenocarcinoma
Ceruminous adenocarcinoma
List of MeSH codes (C04)
Head and neck cancer
Parotidectomy
Pleural disease
Carcinoma
Mucinous cystadenocarcinoma of the lung
Conjunctival squamous cell carcinoma
Odontogenic cyst
Thyroid neoplasm
Index of oral health and dental articles
International Classification of Diseases for Oncology
Hyalinizing clear cell carcinoma
Cysts of the jaws
Ramesh C. Deka
Epithelial-myoepithelial carcinoma of the lung
Oncovirus
Salivary gland
Dentigerous cyst
Salivary gland-like carcinoma of the lung
Short description of cell lines. Tumor: carcinoma, mucoepidermoid
Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor.
October 1976 - Volume 58 - Issue 4 : Plastic and Reconstructive Surgery
New developments in the molecular pathogenesis of head and neck tumors: A review of tumor-specific fusion oncogenes in...
Mucoepidermoid carcinoma - Wikipedia
Malignant Parotid Tumors: Practice Essentials, Anatomy, Diagnosis
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Malignant Tumors of the Palate: Practice Essentials, Etiology, Pathophysiology
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Intraosseous mucoepidermoid carcinoma of the mandible - a rare case report
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Airway Tumors - Lung and Airway Disorders - MSD Manual Consumer Version
Squamous cells in fine-needle aspiration biopsies of salivary gland lesions: potential pitfalls in cytologic diagnosis.
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Pleomorphic adenoma | Registered Dental Hygienists
Nobu Kazawa
Paraffin Tissue Section - Human Lung Tumor, EGFR/KRAS Characterized | BioChain Institute Inc.
Comprehensive analysis of HE4 expression in normal and malignant human tissues | Modern Pathology
Lip Reconstruction Procedures: Background, History of the Procedure, Epidemiology
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Malignant mixed tumor
longest survivor of adenoid cystic carcinoma
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Carcinoma69
- Recently, pathognomonic fusion transcripts have been identified in various uncommon, aggressive head and neck malignancies, including mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC), and NUT midline carcinoma (NMC). (johnshopkins.edu)
- Mucoepidermoid carcinoma (MEC) is the most common type of minor salivary gland malignancy in adults. (wikipedia.org)
- Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, and thyroid gland. (wikipedia.org)
- Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. (wikipedia.org)
- H & E stain Histopathologic image of mucoepidermoid carcinoma of the major salivary gland. (wikipedia.org)
- Relative incidence of parotid tumors, showing mucoepidermoid carcinoma at top right. (wikipedia.org)
- The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
- Introduction: Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. (bvsalud.org)
- Primary intraosseous mucoepidermoid carcinoma (PIOC) of the jaw bones is an extremely rare malignant salivary gland tumor. (bvsalud.org)
- In 1945, Stewart and associates described the mucous secreting and epidermal cellular component of mucoepidermoid carcinoma, thus establishing it as a distinct pathological entity 7 . (bvsalud.org)
- In 1991, after a systematic review of its histology and degree of differentiation, the World Health Organization (WHO) classification recommended that the term "mucoepidermoid tumor" be changed to "mucoepidermoid carcinoma" 11 . (bvsalud.org)
- Lesions included eight pleomorphic adenomas, four Warthin's tumors, two squamous cell carcinomas, two mucoepidermoid cancers, one acinic cell carcinoma, and one melanoma metastasis. (ajnr.org)
- The most common malignant tracheal tumors include squamous cell carcinoma, adenoid cystic carcinoma, carcinoid tumors, and mucoepidermoid carcinomas. (msdmanuals.com)
- Evidence exists of transformation in some cases to carcinoma (termed carcinoma ex-mixed tumor). (rdhmag.com)
- presented a case where there was misinterpretation in diagnosis of a mucoepidermoid carcinoma in a 16-year-old female. (rdhmag.com)
- Mucoepidermoid carcinoma is a relatively common salivary glands tumor. (pneumologia.eu)
- Mucoepidermoid carcinoma of the bronchi and especially trachea is very unusual. (pneumologia.eu)
- After surgery a low grade mucoepidermoid carcinoma was confirmed by pathological examination. (pneumologia.eu)
- MATERIALS AND METHODS: Forty formalin-fixed, paraffinated blocks (20 adenoid cystic carcinoma and 20 mucoepidermoid carcinoma blocks) were selected from the medical archives of Amir A'lam Hospital of Tehran, Iran. (bvsalud.org)
- In mucoepidermoid carcinoma, intratumoral MVD and LVD were greater than peritumoral MVD and LVD (P= 0.001 and P (bvsalud.org)
- CONCLUSION: The higher level of angiogenesis and lymphangiogenesis in mucoepidermoid carcinoma, specifically at the center of tumor, compared to adenoid cystic carcinoma, may be attributed to differences in the clinical behaviors and metastasis of tumors. (bvsalud.org)
- Moreover, considering the high LVD at the center of tumor in mucoepidermoid carcinoma and infrequency of metastasis to regional lymph nodes in adenoid cystic carcinoma, it can play a significant role in metastasis to regional lymph nodes. (bvsalud.org)
- Biopsy indicated a low-grade salivary gland tumor including a mucoepidermoid carcinoma. (archive.org)
- One eye with intraocular invasion of a mucoepidermoid carcinoma was enucleated. (thieme-connect.com)
- But there was no recurrence of CIN/carcinoma in patients who had received a complete tumor resection initially. (thieme-connect.com)
- The Challenge of 'Monomorphic' Mucoepidermoid Carcinoma-Report of a Rare Case with Pure Spindle-Clear Cell Morphology. (qxmd.com)
- Mucoepidermoid carcinoma is a malignant salivary gland tumor which, in most cases, is composed of variable proportions of mucous, epidermoid, and intermediate cells. (qxmd.com)
- We report a case of parapharyngeal mucoepidermoid carcinoma with highly unusual ("monomorphic") light microscopic features as well as atypical immunohistochemical properties. (qxmd.com)
- Mucoepidermoid carcinoma featuring a uniform ("monomorphic") population of neoplastic cells is a novel observation. (qxmd.com)
- Our case increases the spectrum of histopathological appearances that mucoepidermoid carcinoma may display. (qxmd.com)
- 1 It is the second most common intraoral malignant salivary gland tumor 1 following mucoepidermoid carcinoma. (pso-hns.org)
- pleomorphic adenoma was the most common benign tumour while mucoepidermoid carcinoma was the most common malignant tumour. (ijcmas.com)
- Pleomorphic adenomas, followed by Warthin's tumour are the most frequent benign histological types in our country while mucoepidermoid carcinoma and adenoid cystic carcinoma are the most common malignant parotid tumours. (ijcmas.com)
- Clinical Analysis of Primary Tracheobronchial Tumors in Children and Evaluation of the Predicting Models for Mucoepidermoid Carcinoma. (cdc.gov)
- Mucoepidermoid carcinoma (MEC) is the most prevalent malignant tumor originating from the salivary gland. (kaomp.org)
- 점액표피양 암종 (Mucoepidermoid carcinoma, MEC)는 타 액선에서 발생하는 가장 흔한 악성 종양으로, 모든 타액선 종 양의 약 3%에서 15%를 차지하며, 악성 종양의 12%에서 40% 를 차지한다. (kaomp.org)
- Although squamous cell carcinoma is the most common primary malignant tumor of the oral cavity, the most common tumors of the hard palate are of minor salivary gland origin. (medscape.com)
- These include benign tumors such as pleomorphic adenomas, as shown below, and malignant tumors such as mucoepidermoid carcinoma, adenoid cystic carcinoma, and polymorphous low-grade adenocarcinoma. (medscape.com)
- The differential diagnosis of Warthin tumor from mucoepidermoid carcinoma in pediatric cases before the surgery is often difficult and it is not easy to determine the surgical design. (theijcp.org)
- Carcinoma, Mucoepidermoid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
- This graph shows the total number of publications written about "Carcinoma, Mucoepidermoid" by people in this website by year, and whether "Carcinoma, Mucoepidermoid" was a major or minor topic of these publications. (uchicago.edu)
- Below are the most recent publications written about "Carcinoma, Mucoepidermoid" by people in Profiles. (uchicago.edu)
- Mucoepidermoid Carcinoma: A Comparison of Histologic Grading Systems and Relationship to MAML2 Rearrangement and Prognosis. (uchicago.edu)
- Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma. (uchicago.edu)
- Nasal cavity tumefactive fibroinflammatory lesion mimicking recurrent mucoepidermoid carcinoma. (uchicago.edu)
- Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma. (uchicago.edu)
- Childhood and adolescent tracheobronchial mucoepidermoid carcinoma (MEC): a case-series and review of the literature. (uchicago.edu)
- Anti-tumor effect of inhibition of IL-6 signaling in mucoepidermoid carcinoma. (uchicago.edu)
- Gastric carcinoma comprises more than 90% of all gastric malignant tumors. (poznayka.org)
- carcinoma contains abundant pools of mucin in which are seen a small number of tumor cells, sometimes having signet-ring appearance. (poznayka.org)
- Mucoepidermoid carcinoma (MEC), one of the most common salivary gland malignancies, is rare in children. (9lib.co)
- Microscopic analysis revealed a low-grade mucoepidermoid carcinoma (Figure 3). (9lib.co)
- Figure 1: (a) Preoperative intraoral image of a mucoepidermoid carcinoma of the left posterior hard palate with 8 mm diameter and fistula opening (black arrow). (9lib.co)
- Mucoepidermoid carcinoma (MEC) is a rare malignant tumor arising from the bronchial gland. (amhsr.org)
- Hence, the final diagnosis of mucoepidermoid carcinoma (MEC) intermediate grade of the lung was made. (amhsr.org)
- Background: Mucoepidermoid carcinoma ex-pleomorphic adenoma (MECxPA) is an extremely rare salivary gland malignancy. (scirp.org)
- The final pathologic diagnosis was metastatic high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma. (scirp.org)
- Conclusions: We describe a novel presentation of high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma as a metastatic parapharyngeal mass. (scirp.org)
- Carcinoma ex-pleomorphic adenoma (CxPA) is an uncommon malignancy, accounting for roughly 11% of primary tumors of the salivary gland. (scirp.org)
- however, the presence of mucoepidermoid carcinoma (MEC) arising from pleomorphic adenoma (PA) has been rarely reported, with a total of nine cases in the literature. (scirp.org)
- Herein, we report a case of a high-grade mucoepidermoid carcinoma ex-pleomorphic adenoma within the deep lobe of the parotid gland. (scirp.org)
- Final pathology revealed high grade mucoepidermoid carcinoma arising from a pleomorphic adenoma. (scirp.org)
- Mucoepidermoid carcinoma after resection. (kipdf.com)
- Such radiographic features were consistent with a differential diagnosis of odontogenic myxoma, central giant cell granuloma, central mucoepidermoid carcinoma, ameloblastoma, odontogenic keratocystic tumour, and other rare entities. (scirp.org)
- A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane. (lookformedical.com)
- Mucoepidermoid carcinoma (MEC) can be classified into low-, intermediate-, and high-grade tumors based on its histological features. (biomedcentral.com)
- Our findings suggest that LINE-1 methylation differed among histological grade mucoepidermoid carcinoma. (biomedcentral.com)
- The mass would turn out to be a mucoepidermoid carcinoma growing in his airway. (muschealth.org)
- Mucoepidermoid carcinoma is a salivary gland type of cancer that accounts for about 0.2% of lung tumors. (muschealth.org)
Carcinomas11
- Alcian blue-PAS stain Mucoepidermoid carcinomas of the salivary and bronchial glands are characterized by a recurrent t(11;19)(q21;p13) chromosomal translocation resulting in a MECT1-MAML2 fusion gene. (wikipedia.org)
- Abnormal DNA content has been related to aggressive behavior in Mucoepidermoid Carcinomas (MEC), Adenoid Cystic Carcinomas (AdCC), Acinic Cell Carcinomas (ACC) and oncocytomas (Onc) [8]. (researchgate.net)
- There was no significant correlation of ploidy status or SPF with the tumor grades of mucoepidermoid carcinomas. (researchgate.net)
- In a series of 175 human adult tumors, gene expression was highest in ovarian serous carcinomas. (nature.com)
- This study aimed to evaluate and compare the immunoexpression of glucose transporter-1 (GLUT-1) and angiogenic index between pleomorphic adenomas (PAs), adenoid cystic carcinomas (ACCs), and mucoepidermoid carcinomas (MECs) of the salivary glands, and establish associations with the respective subtype/histological grade. (bvsalud.org)
- Surgical specimens from 45 patients - 8 pleomorphic adenomas (PA), 7 Warthin tumours (WT), 5 basal cell adenomas (BA), 6 carcinomas ex-pleomorphic adenoma (CEPA), 6 mucoepidermoid carcinomas (MEC), 5 acinic cell carcinomas (AC), 4 adenoid cystic carcinomas (ACC) and 4 adenocarcinomas not otherwise specified (ADK NOS) - were immunostained. (bvsalud.org)
- We performed tracheal and carinal replacements with aortic allografts in 6 patients with extensive mucoepidermoid (n = 1) or adenoid cystic (n = 5) carcinomas. (nih.gov)
- Mucoepidermoid carcinomas account for about 21% of the malignant tumors of the parotid gland and 10% of the sublingual gland. (uchicago.edu)
- ALDH/CD44 identifies uniquely tumorigenic cancer stem cells in salivary gland mucoepidermoid carcinomas. (uchicago.edu)
- Salivary gland-type tumors of the breast: a spectrum of benign and malignant tumors including "triple negative carcinomas" of low malignant potential. (uchicago.edu)
- Mucoepidermoid Carcinomas Mucoepidermoid carcinomas are rarely reported in birds. (kipdf.com)
Diagnosis7
- This may be due to late diagnosis of these tumors in our patients as most cases diagnosed at advanced stage and the sections were taken from deep tumor tissue to increase the number of tumor cells in our samples. (researchgate.net)
- The tumors may have varying histological appearances consisting of ductal and myoepithelial cells in various stages of development and this fact alone makes a diagnosis very difficult in some cases due to limited or selected tissue samples. (rdhmag.com)
- Knowledge of the expression patterns of HE4 in our survey is useful for application in histopathologic diagnosis, and should be taken into consideration in future studies that examine the role of HE4 as a serological tumor biomarker or as a target for gene-based therapy. (nature.com)
- We discuss the implications of our results in terms of the potential role for HE4 in histopathologic diagnosis, as a serum tumor biomarker, and as a therapeutic target. (nature.com)
- The tumor was resected under general anesthesia with the diagnosis of a malignant salivary tumor on the right palate. (archive.org)
- It suggests that precise preoperative diagnosis is important because the surgery for pediatric cases with parotid gland neoplasm should be designed to remove the tumor completely with an adequate margin. (theijcp.org)
- Early diagnosis can be accomplished if the clinician is alert to persistent pneumonia, coughing and tumor obstruction on image studies. (amhsr.org)
Biopsy7
- In the present study, we show that a tracheal mucoepidermoid tumor biopsy obtained from a 6 year-old patient contained a subpopulation of cells with morphology, clonogenicity and surface markers that overlapped with bone marrow mesenchymal stromal cells (BM-MSCs). (scilifelab.se)
- For ulcerative lesions, obtaining a biopsy specimen from closer to the edge of the tumor is important to avoid the necrotic central component. (medscape.com)
- At a later date, the tumor was diagnosed through biopsy as a pleomorphic adenoma (see Figure 1). (rdhmag.com)
- This contributes to unclear margins during biopsy and difficulty in removal of the entire tumor. (rdhmag.com)
- A subsequent biopsy confirmed a malignant epithelial tumor, with further imaging assisting in determining the surgical approach. (kaomp.org)
- External tumors may be detected by physical examination and can often be diagnosed by needle aspiration, wedge, punch or surgical biopsy. (kipdf.com)
- After confirmation of OM on biopsy, the patient underwent an extended right radical en bloc maxillectomy with immediate reconstruction of the inferior orbital rim. (scirp.org)
Malignancy3
- Conclusion: DNA aneuploidy may be a key indicator for tumors activity and malignancy in SGTs, while the SPF has a minor role in the evaluation of SGTs activity. (researchgate.net)
- A tumor of both low- and high-grade malignancy. (uchicago.edu)
- In humans, these tumors demonstrate variable degrees of malignancy and surgical resection is often curative. (kipdf.com)
Parotid tumors3
- these are discussed in detail in the Medscape Drugs & Diseases article Benign Parotid Tumors . (medscape.com)
- The superficial lobe is the larger of the two and thereby the location of the majority of parotid tumors. (medscape.com)
- The pleomorphic adenoma is the most common benign salivary gland tumor, accounting for 53 to 57% of parotid tumors and 44 to 68% of submandibular tumors. (rdhmag.com)
Resection7
- When the tumour is incompletely resected (positive margins) post-operative radiotherapy gives local control comparable to a complete resection (clear margins). (wikipedia.org)
- Following resection of the tumor specimen, most wounds can be closed primarily. (medscape.com)
- Tracheal tumor resection was followed by carinal restitution (n = 3) and interposition of the graft, splinted by a silicone stent. (nih.gov)
- Tracheal replacement with aortic allografts enables resection of extensive tumors with a curative intent. (nih.gov)
- Resection of the hard palate may be necessary for the management of benign or malignant tumors or as a donor site for a mucosal graft. (medscape.com)
- The indications to perform hard palate resection include excision of malignant and benign tumors, to alleviate complications from tumor burden that compromise the function of the oral cavity, and for facial reconstruction such as in cases of eyelid, lip, and nasal ala deformities. (medscape.com)
- Contraindications to hard palate resection include inability to tolerate general anesthesia , extensive lesions that may require more radical surgical intervention, and tumors that may be more appropriately treated with local irradiation and/or chemotherapy. (medscape.com)
Warthin's1
- It is followed by the second most common benign salivary gland tumor, Warthin's tumor. (rdhmag.com)
Head and neck tumors1
- Epithelial salivary gland neoplasms are rare both in adults and children, accounting for less than 3% of all head and neck tumors. (9lib.co)
Adenomas2
- The purpose of this study was to document the delayed CT enhancement characteristics of parotid pleomorphic adenomas and to preliminarily compare these results with the enhancement characteristics of other parotid gland tumors. (ajnr.org)
- This feature may be useful in selecting an appropriate contrast delay when scanning possible pleomorphic adenomas to improve lesion conspicuity and, potentially, to better distinguish these tumors from other parotid abnormalities. (ajnr.org)
Neoplasms3
- Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
- ABSTRACT BACKGROUND: Neuroendocrine tumors are rare neoplasms of uncertain biological behavior. (bvsalud.org)
- The benign neoplasms of parotid glands in children are mostly pleomorphic adenoma and Warthin tumor is extremely rare. (theijcp.org)
Wilms1
- The Wilms tumor 1 gene, WT1 , is overexpressed in various types of cancer, including gastric cancer. (sagepub.com)
High-grade mucoepidermoid1
- Lymph node involvement is of special concern in SCC and high-grade mucoepidermoid cancer. (medscape.com)
Prognosis3
- Generally, there is a good prognosis for low-grade tumors, and a poor prognosis for high-grade tumors, however recent research have found reoccurring low grade tumors also have a poor prognosis. (wikipedia.org)
- Perform staging of the tumor according to the American Joint Committee on Cancer staging protocol because this is of critical importance to the patient's prognosis. (medscape.com)
- MEC is a comparatively rare low‑grade tumor, which reportedly carries a good prognosis with early surgical intervention. (amhsr.org)
Adenocarcinoma2
- Cystadenocarcinoma (adenocarcinoma NOS) is a rare disease among salivary tumors. (archive.org)
- Polymorphous low-grade adenocarcinoma (PLGA) is a malignant epithelial tumor characterized by cytologic uniformity, morphologic diversity, an infiltrative growth pattern, and low metastatic potential. (pso-hns.org)
Benign tumors1
- The malignant SGTs had higher SPF than the benign tumors but with no significant difference. (researchgate.net)
Tracheal2
- Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor. (scilifelab.se)
- Nobu Kazawa having her international experience includes various programs, contributions and participation in different countries for diverse fields of Tracheal Muco epidermoid Tumor with CRTC1-MAML2 Fusion Gene in a 12- Year-Old Boy. (longdom.org)
Lesion2
- The tumor may also be found in the palate and in this location, the growth appears as a bulbous, nonulcerated, firm lesion. (rdhmag.com)
- There is a rare variant of in situ malignant mixed tumor: in these cases the same kinds of malignant myoepithelial or epithelial cells are present, they invade the capsule and vessels inside the lesion, but are not invasive towards the surrounding salivary gland tissue. (eurocytology.eu)
Major salivary glands2
- Pleomorphic adenoma tumors occur in the major salivary glands of the parotid and the submandibular region. (rdhmag.com)
- The tumor is found almost exclusively in minor salivary glands and is rare in extraoral locations, including major salivary glands. (pso-hns.org)
Extension of the tumor2
- However, the presence of extension of the tumor to the overlying skin or surrounding structures may require reconstructive procedures. (medscape.com)
- Almost half of patients present with extension of the tumor beyond the soft palate. (medscape.com)
Squamous cells2
- citation needed] This tumor is not encapsulated and is characterized by squamous cells, mucus-secreting cells, and intermediate cells. (wikipedia.org)
- The tumor is easily diagnosable on cytology in dedifferentiated and invasive cases: it consists mostly of malignant squamous, in some cases keratinizing squamous cells, atypical glandular cells. (eurocytology.eu)
Lobe of the gland2
- Dysphagia or a sensation of a foreign body in the oropharynx - Indicates a tumor of the deep lobe of the gland. (medscape.com)
- A superficial parotidectomy, removing the lobe of the gland containing the tumor is performed. (rdhmag.com)
Classification1
- The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs-Part B: Prostate and Urinary Tract Tumors. (who.int)
Glandular3
- Originally, "benign mixed tumor" was used to describe the mixed nature of the tumor, which may include metaplastic cartilage, fat, bone, etc., in addition to the glandular epithelial component. (rdhmag.com)
- The tumor featured heretofore undescribed histopathological features: sheets and nests composed of monomorphic neoplastic (plump spindle to epithelioid) cells with no mucous, intermediate, glandular/columnar, or any other cell type identified. (qxmd.com)
- A malignant epithelial tumor with a glandular organization. (lookformedical.com)
Remove the tumor1
- The team now had to figure out the best way to remove the tumor. (muschealth.org)
Behavior2
- S-phase value is correlated with the behavior of the tumors [13, 14]. (researchgate.net)
- Results suggest that differences in biological behavior of the studied tumors are related to GLUT-1. (bvsalud.org)
Palate6
- Specific treatment of palate cancer depends on the location of the tumor (hard vs soft palate), stage of the tumor, and pathologic type of the cancer. (medscape.com)
- These tumors may also be found in the palate, affecting minor salivary glands. (rdhmag.com)
- When occurring in the palate, some bone may need to be removed along with the actual tumor. (rdhmag.com)
- A 69-year-old man with an increasing tumor in the right palate was referred to our department. (archive.org)
- However, in tumors with posterior soft palate extension, retropharyngeal nodes may be involved. (medscape.com)
- Tumors of the hard palate are uncommon. (medscape.com)
Metastatic2
- One patient who had 50-gene panel only also had his metastatic site (esophagus) of his tumor tested with FoundationOne. (cancerindex.org)
- Generally, solid tumors are best treated with surgical excision, while systemic neoplastic processes (ie, systemic lymphoma, metastatic conditions) are most effectively managed with use of systemic chemotherapy. (kipdf.com)
Connective tissue1
- The tumor is encapsulated by thick connective tissue, but portions may also extend into salivary tissue. (rdhmag.com)
Malignancies2
- Tumor-specific recurrent chromosomal translocations and novel fusion oncogenes in aggressive head and neck malignancies have diagnostic, therapeutic, and prognostic implications. (johnshopkins.edu)
- Postoperative radiation is usually indicated for all parotid malignancies with the exception of small low-grade tumors with no evidence of local invasion or nodal/distant spread. (medscape.com)
Epithelial cells4
- Confluent NCI-H292 human mucoepidermoid airways epithelial cells were pretreated with AZM or MDM for 2 h and then stimulated with 200 nmol/l phorbol 12-myristate 13-acetate (PMA) for 8 h. (karger.com)
- Cigana C, Assael BM, Melotti P: Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells. (karger.com)
- There were scant epithelial components with residual normal ductules among chondromyxoid stroma, epithelial cells intermingled with mucin-positive cells, and calcified areas merging with viable and necrotic tumor. (scirp.org)
- It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Airway4
- The most common noncancerous (benign) airway tumor is a squamous papilloma, although other benign conditions can also occur. (msdmanuals.com)
- Doctors may consider an airway tumor if symptoms develop gradually and if standard treatments are ineffective, for example, if drugs used to treat asthma do not relieve wheezing. (msdmanuals.com)
- Certain types of airway tumors should be removed surgically if possible. (msdmanuals.com)
- Laser vaporization, photodynamic therapy, cryotherapy, and endobronchial brachytherapy are options to remove a tumor blocking an airway. (msdmanuals.com)
Cytology2
- No cytology publication on this latter tumor until now. (eurocytology.eu)
- 6 Tumor cytology and histology are quite characteristic - recognizing the constant cytological appearance despite the diversity of architectural tumor patterns should aid one in diagnosing PLGA. (pso-hns.org)
Intermediate1
- This tumor is characterized by mucus secretion, cell type can be intermediate or squamous. (pneumologia.eu)
Invasiveness1
- The tumor has not shown invasiveness. (eurocytology.eu)