Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations.
The oval-shaped oral cavity located at the apex of the digestive tract and consisting of two parts: the vestibule and the oral cavity proper.
Lining of the INTESTINES, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. In the SMALL INTESTINE, the mucosa is characterized by a series of folds and abundance of absorptive cells (ENTEROCYTES) with MICROVILLI.
Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones.
The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.
Tumors or cancer of the MOUTH.
An EPITHELIUM with MUCUS-secreting cells, such as GOBLET CELLS. It forms the lining of many body cavities, such as the DIGESTIVE TRACT, the RESPIRATORY TRACT, and the reproductive tract. Mucosa, rich in blood and lymph vessels, comprises an inner epithelium, a middle layer (lamina propria) of loose CONNECTIVE TISSUE, and an outer layer (muscularis mucosae) of SMOOTH MUSCLE CELLS that separates the mucosa from submucosa.
That portion of the nasal mucosa containing the sensory nerve endings for SMELL, located at the dome of each NASAL CAVITY. The yellow-brownish olfactory epithelium consists of OLFACTORY RECEPTOR NEURONS; brush cells; STEM CELLS; and the associated olfactory glands.
Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed)
Total lack of teeth through disease or extraction.
The mucous lining of the LARYNX, consisting of various types of epithelial cells ranging from stratified squamous EPITHELIUM in the upper larynx to ciliated columnar epithelium in the rest of the larynx, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Decreased salivary flow.
A species of ENTEROVIRUS infecting humans and containing 10 serotypes, mostly coxsackieviruses.
Devices or pieces of equipment placed in or around the mouth or attached to instruments to protect the external or internal tissues of the mouth and the teeth.
The shortest and widest portion of the SMALL INTESTINE adjacent to the PYLORUS of the STOMACH. It is named for having the length equal to about the width of 12 fingers.
The portion of the GASTROINTESTINAL TRACT between the PYLORUS of the STOMACH and the ILEOCECAL VALVE of the LARGE INTESTINE. It is divisible into three portions: the DUODENUM, the JEJUNUM, and the ILEUM.
Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.
The muscular membranous segment between the PHARYNX and the STOMACH in the UPPER GASTROINTESTINAL TRACT.
A muscular organ in the mouth that is covered with pink tissue called mucosa, tiny bumps called papillae, and thousands of taste buds. The tongue is anchored to the mouth and is vital for chewing, swallowing, and for speech.
An organ of digestion situated in the left upper quadrant of the abdomen between the termination of the ESOPHAGUS and the beginning of the DUODENUM.
Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin.
Spasmodic contraction of the masseter muscle resulting in forceful jaw closure. This may be seen with a variety of diseases, including TETANUS, as a complication of radiation therapy, trauma, or in association with neoplastic conditions.
The part of the face that is below the eye and to the side of the nose and mouth.
A condition in which there is a change of one adult cell type to another similar adult cell type.
A spiral bacterium active as a human gastric pathogen. It is a gram-negative, urease-positive, curved or slightly spiral organism initially isolated in 1982 from patients with lesions of gastritis or peptic ulcers in Western Australia. Helicobacter pylori was originally classified in the genus CAMPYLOBACTER, but RNA sequencing, cellular fatty acid profiles, growth patterns, and other taxonomic characteristics indicate that the micro-organism should be included in the genus HELICOBACTER. It has been officially transferred to Helicobacter gen. nov. (see Int J Syst Bacteriol 1989 Oct;39(4):297-405).
Removal and pathologic examination of specimens in the form of small pieces of tissue from the living body.
Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
An offensive, foul breath odor resulting from a variety of causes such as poor oral hygiene, dental or oral infections, or the ingestion of certain foods.
The region between the sharp indentation at the lower third of the STOMACH (incisura angularis) and the junction of the PYLORUS with the DUODENUM. Pyloric antral glands contain mucus-secreting cells and gastrin-secreting endocrine cells (G CELLS).
The mucous membrane lining the RESPIRATORY TRACT, including the NASAL CAVITY; the LARYNX; the TRACHEA; and the BRONCHI tree. The respiratory mucosa consists of various types of epithelial cells ranging from ciliated columnar to simple squamous, mucous GOBLET CELLS, and glands containing both mucous and serous cells.
Either of the two fleshy, full-blooded margins of the mouth.
Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
An appliance used as an artificial or prosthetic replacement for missing teeth and adjacent tissues. It does not include CROWNS; DENTAL ABUTMENTS; nor TOOTH, ARTIFICIAL.
One or more layers of EPITHELIAL CELLS, supported by the basal lamina, which covers the inner or outer surfaces of the body.
A part of the upper respiratory tract. It contains the organ of SMELL. The term includes the external nose, the nasal cavity, and the PARANASAL SINUSES.
Histochemical localization of immunoreactive substances using labeled antibodies as reagents.
Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Tumors or cancer of the STOMACH.
A dental specialty concerned with the diagnosis and surgical treatment of disease, injuries, and defects of the human oral and maxillofacial region.
Surgical procedures used to treat disease, injuries, and defects of the oral and maxillofacial region.
General or unspecified injuries involving the face and jaw (either upper, lower, or both).
The surgical removal of HEMORRHOIDS.
A prosthetic appliance for the replacement of areas of the maxilla, mandible, and face, missing as a result of deformity, disease, injury, or surgery. When the prosthesis replaces portions of the mandible only, it is referred to as MANDIBULAR PROSTHESIS.
Fractures of the upper jaw.
The offspring in multiple pregnancies (PREGNANCY, MULTIPLE): TWINS; TRIPLETS; QUADRUPLETS; QUINTUPLETS; etc.

Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris. (1/2113)

Patients with pemphigus foliaceus (PF) have blisters on skin, but not mucous membranes, whereas patients with pemphigus vulgaris (PV) develop blisters on mucous membranes and/or skin. PF and PV blisters are due to loss of keratinocyte cell-cell adhesion in the superficial and deep epidermis, respectively. PF autoantibodies are directed against desmoglein (Dsg) 1; PV autoantibodies bind Dsg3 or both Dsg3 and Dsg1. In this study, we test the hypothesis that coexpression of Dsg1 and Dsg3 in keratinocytes protects against pathology due to antibody-induced dysfunction of either one alone. Using passive transfer of pemphigus IgG to normal and DSG3(null) neonatal mice, we show that in the areas of epidermis and mucous membrane that coexpress Dsg1 and Dsg3, antibodies against either desmoglein alone do not cause spontaneous blisters, but antibodies against both do. In areas (such as superficial epidermis of normal mice) where Dsg1 without Dsg3 is expressed, anti-Dsg1 antibodies alone can cause blisters. Thus, the anti-desmoglein antibody profiles in pemphigus sera and the normal tissue distributions of Dsg1 and Dsg3 determine the sites of blister formation. These studies suggest that pemphigus autoantibodies inhibit the adhesive function of desmoglein proteins, and demonstrate that either Dsg1 or Dsg3 alone is sufficient to maintain keratinocyte adhesion.  (+info)

Circadian variation in the expression of cell-cycle proteins in human oral epithelium. (2/2113)

At the tissue level, there is experimental and clinical data to suggest a cytokinetic coordination of the cell cycle with a greater proportion of cycling cells entering S-phase and mitosis at specific times of the day. The association of certain cell-cycle proteins with defined events in the cell cycle is well established and may be used to study the timing of cell-cycle phases over 24 hours. In this study oral mucosal biopsies were obtained from six normal human volunteers at 4-hour intervals, six times over 24 hours. Using immunohistochemistry, the number of positive cells expressing the proteins p53, cyclin-E, cyclin-A, cyclin-B1, and Ki-67 was determined for each biopsy and expressed as the number of positive cells per mm of basement membrane. We found a statistically significant circadian variation in the nuclear expression of all of these proteins with the high point of expression for p53 at 10:56 hours, cyclin-E at 14:59 hours, cyclin-A at 16:09 hours, cyclin-B1 at 21:13 hours, and Ki-67 at 02:50 hours. The circadian variation in the nuclear expression of cyclins-E (G1/S phase), -A (G2-phase), and -B1 (M-phase) with a normal physiological progression over time suggests a statistically significant circadian variation in oral epithelial cell proliferation. The finding of a circadian variation in the nuclear expression of p53 protein corresponding to late G1 is novel. This information has clinical implications regarding the timing of chemotherapy and radiotherapy.  (+info)

Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. (3/2113)

The pathogenesis of candidiasis involves invasion of host tissues by filamentous forms of the opportunistic yeast Candida albicans. Morphology-specific gene products may confer proinvasive properties. A hypha-specific surface protein, Hwp1, with similarities to mammalian small proline-rich proteins was shown to serve as a substrate for mammalian transglutaminases. Candida albicans strains lacking Hwp1 were unable to form stable attachments to human buccal epithelial cells and had a reduced capacity to cause systemic candidiasis in mice. This represents a paradigm for microbial adhesion that implicates essential host enzymes.  (+info)

Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck. (4/2113)

The purpose of this study was to determine whether cyclooxygenase-2 (COX-2) was overexpressed in squamous cell carcinoma of the head and neck (HNSCC). Quantitative reverse transcription-PCR, immunoblotting, and immunohistochemistry were used to assess the expression of COX-2 in head and neck tissue. Mean levels of COX-2 mRNA were increased by nearly 150-fold in HNSCC (n = 24) compared with normal oral mucosa from healthy volunteers (n = 17). Additionally, there was about a 50-fold increase in amounts of COX-2 mRNA in normal-appearing epithelium adjacent to HNSCC (n = 10) compared with normal oral mucosa from healthy volunteers. Immunoblotting demonstrated that COX-2 protein was present in six of six cases of HNSCC but was undetectable in normal oral mucosa from healthy subjects. Immunohistochemical analysis showed that COX-2 was expressed in both HNSCC and adjacent normal-appearing epithelium. Taken together, these results suggest that COX-2 may be a target for the prevention or treatment of HNSCC.  (+info)

Nasopharyngeal-associated lymphoreticular tissue (NALT) immunity: fimbriae-specific Th1 and Th2 cell-regulated IgA responses for the inhibition of bacterial attachment to epithelial cells and subsequent inflammatory cytokine production. (5/2113)

To investigate the antibacterial activity of mucosal Th1 and Th2 immune responses induced nasally and orally, mice were immunized with mucosal vaccine containing fimbrial protein of Porphyromonas gingivalis, a causative agent for a destructive chronic inflammation in the periodontium, and cholera toxin (CT) as mucosal adjuvant. Nasal vaccine containing low doses of fimbriae (10 micrograms) and CT (1 microgram) induced Ag-specific Th1/Th2-type response in CD4+ T cells in mucosal effector tissues, including nasal passage and submandibular glands, which accounted for the generation of Ag-specific IgA-producing cells. In contrast, oral immunization required higher amounts of fimbriae and CT for the induction of Ag-specific IgA responses. Fimbriae-specific IgA mAbs generated from submandibular glands of nasally immunized mice inhibited P. gingivalis attachment to and reduced subsequent inflammatory cytokine production from epithelial cells. These findings suggest that nasal vaccination is an effective immunization regimen for the induction of Ag-specific Th1 and Th2 cell-driven IgA immune responses that possess the ability to inhibit bacterial attachment to epithelial cells and subsequent inflammatory cytokine production.  (+info)

Transmission of human immunodeficiency virus type 1 through breast-feeding: how can it be prevented? (6/2113)

One-third to two-thirds of maternal transmission of human immunodeficiency virus type 1 (HIV-1) infection to breast-fed infants can be attributed to ingestion of breast milk. The presence of HIV-1 as cell-free and as cell-associated virus in milk has been documented. Several substances in breast milk may be protective against transmission, including maternal anti-HIV antibodies, vitamin A, lactoferrin, and secretory leukocyte protease inhibitor. The portal of virus entry in the infant's gastrointestinal tract is unknown but may involve breaches in mucosal surfaces, transport across M cells, or direct infection of other epithelial cells, such as enterocytes. Timing of transmission of HIV-1 during lactation should be further clarified. An early rebound of plasma viremia after withdrawal of antiretrovirals was recently detected. This rebound may reduce the benefit of antiretroviral prophylaxis when women breast-feed their infants. Interventions should be viewed from the public health perspective of risks of infant morbidity and mortality associated with breast-feeding versus risks from formula-feeding.  (+info)

Oral transmission of primate lentiviruses. (7/2113)

Oral transmission of human immunodeficiency virus type 1 (HIV-1) is well documented in children who become infected postnatally through breast milk. In contrast, epidemiologic surveys have yielded conflicting data regarding oral HIV-1 transmission among adults, even though case reports have described seroconversion and the development of AIDS in adults whose only risk was oral-genital contact. To study oral virus transmission in primate models, we exposed rhesus macaques of various ages to cell-free simian immunodeficiency virus (SIV), including uncloned and molecularly cloned viruses. In neonates, viremia and AIDS developed after nontraumatic oral exposure to several SIV strains. Furthermore, chimeric simian human immunodeficiency viruses containing the HIV-1 envelope can also cross intact upper gastrointestinal mucosal surfaces in neonates. In adult macaques, infection and AIDS have resulted from well-controlled, nontraumatic, experimental oral exposure to different strains of SIV. These findings have implications for the risks of HIV-1 transmission during oral-genital contact.  (+info)

Mucosal dendritic cells and immunodeficiency viruses. (8/2113)

Dendritic cells [DCs] have been implicated in the pathogenesis of human immunodeficiency virus type 1 (HIV-1). When skin was used as a model for mucosae, the cutaneous DC-T cell milieu allowed the growth of HIV-1 and much of the newly produced virus could be detected in multinucleated DC-T cell syncytia. Such virus replication occurs irrespective of the genetic subtype, the syncytium- and non-syncytium-inducing capacities of the viruses, and whether they are classified as T cell- or macrophage-tropic. Similar DC-syncytia have been identified within the mucosal surfaces of the tonsillar tissue of HIV-1-infected persons. More recently, it was demonstrated that DC-T cell mixtures from the skin, mucosae, and blood of healthy macaques similarly support the replication of simian immunodeficiency virus. In both the human and monkey systems, active virus replication requires the presence of both DCs and T cells. Further studies using the macaque model are underway to elucidate the role of DCs in the transmission and spread of HIV infection.  (+info)

TY - JOUR. T1 - Comparative phenotypic and functional analysis of migratory dendritic cell subsets from human oral mucosa and skin. AU - Kosten, Ilona Jennifer. AU - Van De Ven, Rieneke. AU - Thon, Maria. AU - Gibbs, Susan. AU - De Gruijl, Tanja D.. PY - 2017/7/1. Y1 - 2017/7/1. N2 - Antigen exposure to oral mucosa is generally thought to lead to immune tolerance induction. However, very little is known about the subset composition and function of dendritic cells (DC) migrating from human oral mucosa. Here we show that migratory DC from healthy human gingival explants consist of the same phenotypic subsets in the same frequency distribution as DC migrating from human skin. The gingival CD1a+ Langerhans cell and interstitial DC subsets lacked CXCR4 expression in contrast to their cutaneous counterparts, pointing to different migration mechanisms, consistent with previous observations in constructed skin and gingival equivalents. Remarkably, without any exogenous conditioning, gingival explants ...
It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists engaged in large-scale genetic biomarker studies. We assessed the genotyping efficiency (GE) and genotyping concordance (GC) of buccal cell DNA samples compared to corresponding blood DNA samples, from 32 Nurses Health Study (NHS) participants using the Illumina Infinium 660W-Quad platform. We also assessed how GE and GC accuracy varied as a function of DNA concentration using serial dilutions of buccal DNA samples. Finally we determined the nature and genomic distribution of discordant genotypes in buccal DNA samples. The mean GE of undiluted buccal cell DNA samples was high (99.32%), as was the GC between the paired buccal and blood samples (99.29%). GC between the dilutions versus the undiluted buccal DNA was also very high (greater than ...
It is unclear if buccal cell samples contain sufficient human DNA with adequately sized fragments for high throughput genetic bioassays. Yet buccal cell sample collection is an attractive alternative to gathering blood samples for genetic epidemiologists engaged in large-scale genetic biomarker studies. We assessed the genotyping efficiency (GE) and genotyping concordance (GC) of buccal cell DNA samples compared to corresponding blood DNA samples, from 32 Nurses Health Study (NHS) participants using the Illumina Infinium 660W-Quad platform. We also assessed how GE and GC accuracy varied as a function of DNA concentration using serial dilutions of buccal DNA samples. Finally we determined the nature and genomic distribution of discordant genotypes in buccal DNA samples. The mean GE of undiluted buccal cell DNA samples was high (99.32%), as was the GC between the paired buccal and blood samples (99.29%). GC between the dilutions versus the undiluted buccal DNA was also very high (greater than ...
Purpose: The oral mucosal epithelium shows substantial potential for use in regenerative medicine, including the treatment of ocular surface disease. The rationale for using oral mucosal cells is the possibility of treating bilateral ocular surface stem cell disease without the use of immunosuppression. The present project determines the ideal harvesting site for oral mucosal biopsies and the optimum culture media for these cells.. Methods: Pieces of oral epithelium were used from four locations: buccal mucosa (BM), hard palate (HP), lower lip (LL), and transition zone of the lower lip (TZ) of Sprague-Dawley rats. Explants were grown in four different culture media for six days. The media were 1) RPMI 1640 with 10% heat- inactivated fetal bovine serum (FBS), 2 mM L-glutamine, and 50 IU/mL penicillin-streptomycin; 2) EpiLife with epidermal growth supplement; 3) oral keratinocyte media (OKM) with oral keratinocyte growth factor; and 4) DMEM and Ham 12 (1:1 mixture) supplemented with 10% FBS, 5 ...
TY - JOUR. T1 - EXPRESSION of Cyclooxygenase-1 and cyclooxigenase-2 in normal and pathological human oral mucosa. AU - Buscemi, Maria. AU - Burruano, Francesco. AU - Tortorici, Silvia. AU - Leone, Angelo. AU - Gerbino, Aldo. AU - Mauro, Annamaria. AU - Lipari, Luana. AU - Provenzano, Salvatore. PY - 2010. Y1 - 2010. N2 - Abstract: Cyclooxigenase (COX) is the rate-limiting enzyme for the conversion of arachidonic acid (AA) to prostaglandins(PGs). Two isoforms of COX have been identified: COX-1 is constitutively expressed in many cells and is involved in cellhomeostasis, angiogenesis and cell-cell signalling; COX-2 is not expressed in normal condition however it is stronglyexpressed in inflammation. The oral cavity is costantly exposed to physical and chemical trauma that could lead to mucosalreactions such as hyperplasia, dysplasia and cancer. Early diagnosis is the most important issue to address for a positiveoutcome of oral cancer; therefore it would be useful to identify molecular markers ...
TY - JOUR. T1 - EXPRESSION of Cyclooxygenase-1 and cyclooxigenase-2 in normal and pathological human oral mucosa. AU - Leone, Angelo. AU - Gerbino, Aldo. AU - Buscemi, Maria. AU - Burruano, Francesco. AU - Tortorici, Silvia. AU - Mauro, Annamaria. AU - Lipari, Luana. AU - Provenzano, Salvatore. PY - 2010. Y1 - 2010. N2 - Abstract: Cyclooxigenase (COX) is the rate-limiting enzyme for the conversion of arachidonic acid (AA) to prostaglandins(PGs). Two isoforms of COX have been identified: COX-1 is constitutively expressed in many cells and is involved in cellhomeostasis, angiogenesis and cell-cell signalling; COX-2 is not expressed in normal condition however it is stronglyexpressed in inflammation. The oral cavity is costantly exposed to physical and chemical trauma that could lead to mucosalreactions such as hyperplasia, dysplasia and cancer. Early diagnosis is the most important issue to address for a positiveoutcome of oral cancer; therefore it would be useful to identify molecular markers ...
TY - JOUR. T1 - Immune responses to Candida albicans in models of in vitro reconstituted human oral epithelium. AU - Wagener, Jeanette. AU - Mailänder-Sanchez, Daniela. AU - Schaller, Martin. PY - 2012. Y1 - 2012. N2 - In this protocol, we describe the application of commercially available three-dimensional organotypic tissues of human oral mucosa to study the interaction between Candida albicans and epithelial cells. Infection experiments show high reproducibility and can be used to analyse directly pathogen/epithelial cell interactions. However, the system is also very flexible. Using histological, biochemical, immunological, and molecular methods, it is possible to analyse several stages of infection by C. albicans wild type or mutant strains and demonstrate the consequence of disrupting genes encoding putative virulence factors required for host cell invasion and immune defence induction. This model provides information about host and pathogen protein and gene expression during direct ...
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Background: The human microbiota is postulated to affect cancer risk, but collecting microbiota specimens with prospective follow-up for diseases will take time. Buccal cell samples have been obtained from mouthwash for the study of human genomic DNA in many cohort studies. Here, we evaluate the feasibility of using buccal cell samples to examine associations of human microbiota and disease risk.. Methods: We obtained buccal cells from mouthwash in 41 healthy participants using a protocol that is widely employed to obtain buccal cells for the study of human DNA. We compared oral microbiota from buccal cells with that from eight other oral sample types collected by following the protocols of the Human Microbiome Project. Microbiota profiles were determined by sequencing 16S rRNA gene V3-V4 region.. Results: Compared with each of the eight other oral samples, the buccal cell samples had significantly more observed species (P , 0.002) and higher alpha diversity (Shannon index, P , 0.02). The ...
TY - JOUR. T1 - Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium. AU - Komori, Taishi. AU - Ono, Mitsuaki. AU - Hara, Emilio satoshi. AU - Ueda, Junji. AU - Nguyen, Ha Thi Thu. AU - Nguyen, Ha Thi. AU - Yonezawa, Tomoko. AU - Maeba, Takahiro. AU - Ono, Aya. AU - Takarada, Takeshi. AU - Momota, Ryusuke. AU - Maekawa, Kenji. AU - Kuboki, Takuo. AU - Oohashi, Toshitaka. PY - 2018/12/1. Y1 - 2018/12/1. N2 - Keratinized mucosa is of fundamental importance to maintain healthy gingival tissue, and understanding the mechanisms of oral mucosa keratinization is crucial to successfully manage healthy gingiva. Previous studies have shown a strong involvement of the basement membrane in the proliferation and differentiation of epithelial cells. Therefore, first, to identify the keratinized mucosa-specific basement membrane components, immunohistochemical analysis for the six alpha chains of type IV collagen was performed in 8-week-old mice. No difference in ...
A significant problem in drug development of novel small molecules is the lack of available tissues (surrogate tissues) that allow for the assessment of the molecular and biochemical effects of (targeted-therapies) drug action. The information obtained from surrogate tissues might help us validate previous preclinical studies with those agents and also dose them in a more rational way. Oral keratinocytes, which are accessible by non-invasive means, might be useful to assess drug action. The proposed study seeks to investigate the genetic, molecular, and biochemical effects of novel agents in oral buccal mucosal cells. Patients already enrolled in Phase I and II clinical trials for neoplastic diseases at the Clinical Center will undergo oral cytobrushing before and during therapy to determine the molecular and biochemical effects of novel agents in the oral mucosa cells. Similar studies will be performed in peripheral blood mononuclear cells. In order to validate to compare and compare the oral ...
The Streptococcus genus comprises ninety-two recognized species that are present in a wide variety of habitats [1]. In humans and animals, a number of streptococcal species are important pathogens (e.g., S. pneumoniae, S. pyogenes, S. suis, and S. mutans), while others are members of mutualistic microflora (e.g., S. oralis, S. downei, S. dentirousetti, and S. salivarius). The species of the Streptococcus genus have been divided into six groups (anginosus, bovis, mitis, mutans, pyogenic, and salivarius) based on 16S rDNA phylogenetic inferences [2]. According to these authors, the salivarius group is composed of three species: (1) S. salivarius, a pioneer colonizer of the human oral mucosa that is isolated mainly from the dorsum of the tongue, the cheeks, and the palate [3], (2) S. vestibularis, a mutualistic bacterium that is present on the vestibulum of the human oral mucosa [4], and (3) S. thermophilus, a thermophilic species [5] that is part of starter cultures used in the production of ...
Purpose: To induce the expression of corneal epithelium-specific cytokeratin 3 (K3) in immortalized human oral mucosal epithelial cells (OKF6/TERT cells) using lentiviral transduction of Pax6.. Methods: OKF6/TERT cells were transduced with two types of lentiviruses, each carrying one of the two variants of Pax6 (Pax6 variant 1 and 2). The cells were cultured in modified keratinocyte serum-free medium (K-sfm) for 3 days after transduction and were cultured in keratinocyte conditioned medium (KCM) with 3T3 feeder cells for another 11 days to stratify them. The gene expressions were examined with quantitative reverse transcription PCR (qRT-PCR) and immunofluorescence imaging on day 3 and day 14.. Results: OKF6/TERT cells had no expression of K3 without transduction of Pax6 (Gene expression compared to GAPDH was 0.01±0.00). OKF6/TERT cells expressed K3 on day 3 only when they were transduced with Pax6 variant 1 (Gene expression compared to GAPDH was 7.31±0.66, P,0.05). Mucin 16 (MUC16) was also ...
Additional file 1: of Transplantation of oral mucosal epithelial cells seeded on decellularized and lyophilized amniotic membrane for the regeneration of injured endometrium
Introduction: Vaginal delivery of medication is advantageous in allowing for the medication to avoid first-pass metabolism and gastrointestinal degrad...
The oral mucosa is the mucous membrane lining the inside of the mouth and consists of stratified squamous epithelium termed oral epithelium and an underlying connective tissue termed lamina propria. The oral cavity has sometimes been described as a mirror that reflects the health of the individual. Changes indicative of disease are seen as alterations in the oral mucosa lining the mouth, which can reveal systemic conditions, such as diabetes or vitamin deficiency, or the local effects of chronic tobacco or alcohol use. Oral mucosa can be divided into three main categories based on function and histology: Masticatory mucosa, keratinized stratified squamous epithelium, found on the dorsum of the tongue, hard palate and attached gingiva. Lining mucosa, nonkeratinized stratified squamous epithelium, found almost everywhere else in the oral cavity, including the: Buccal mucosa refers to the inside lining of the cheeks and floor of the mouth and is part of the lining mucosa. Labial mucosa refers to ...
This page includes the following topics and synonyms: Labial mucosa, Buccal mucosa, Masticatory Mucosa, Movable Mucosa, Oral Mucosa.
Background/Aim: In order to produce an animal model for oral mucositis induced by anticancer drugs, it is necessary to maintain an immunosuppressive state. We determined the optimal dose and frequency of 5-fluorouracil for a model mouse production. In addition, we used this model to investigate the effect of GGsTop® gelation on the therapeutic effect of oral mucositis. Materials and Methods: Changes in body weight and white blood cell count were measured to determine the optimal dosing schedule. The therapeutic effect of GGsTop® gel using chitosan was evaluated by observing changes in the ulcer area for three weeks and measuring collagen and glutathione concentrations in oral mucosal tissue. Results: The optimal dose and frequency of 5-fluorouracil were found to be 50 mg/kg every four days. It was revealed that the therapeutic effect of GGsTop® was enhanced by gelation. Conclusion: GGsTop® gel is suggested to be a promising formulation for the treatment of oral mucositis. ...
Most treatment failure of buccal mucosal cancer post surgery is locoregional recurrence. We tried to figure out how close the surgical margin being unsafe and needed further adjuvant treatment. Between August 2000 and June 2008, a total of 110 patients with buccal mucosa carcinoma (25 with stage I, 31 with stage II, 11 with stage III, and 43 with Stage IV classified according to the American Joint Committee on Cancer 6th edition) were treated with surgery alone (n = 32), surgery plus postoperative radiotherapy (n = 38) or surgery plus adjuvant concurrent chemoradiotherapy (n = 40). Main outcome measures: The primary endpoint was locoregional disease control. The median follow-up time at analysis was 25 months (range, 4-104 months). The 3-year locoregional control rates were significantly different when a 3-mm surgical margin (≤3 versus >3 mm, 71% versus 95%, p = 0.04) but not a 5-mm margin (75% versus 92%, p = 0.22) was used as the cut-off level. We also found a quantitative correlation between
Aim: To evaluate the prevalence of oral mucosa lesions among diabetic patients in, South Kerala, India. Methods: A cross- sectional observational stud..
White lesions are the pathological changes seen in the oral cavity involving the soft tissues like buccal mucosa, palatal mucosa, tongue and floor of mouth.
Methylation status in normal oral epithelial cells and HNSCC.A: RUNX3 expression was examined after 5-aza-2′-deoxycytidine (5-Aza) treatment. HSC4 cells were
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OUTLINE: This is a multicenter study.. Previously procured and archived bone marrow aspirate samples, blood and buccal cell samples, and bone marrow biopsy slides are analyzed for FLT3 ITD, MLL PTD, NPM1, KIT, KRAS, NRAS, CEBPA, WT1, JAK2, RUNX1, TET2, ASXL1, IDH1 and IDH2, and CBL mutations, CBF fusion genes, levels of BAALC, ERG, EVI1, MN1, and APP microarray gene-expression, microRNA gene-expression signature, levels of methylation of genes silenced in AML, and genomic DNA by PCR amplification, RT-PCR, and denaturing high-performance liquid chromatography. ...
Yu G, Phillips S, Gail MH, Goedert JJ, Humphrys M, Ravel J, Ren Y, Caporaso NE. Evaluation of Buccal Cell Samples for Studies of Oral Microbiota. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2017 Feb 0; 26(2):249-253. Epub 2016 Oct 21. 1/2017 ...
In 16 patients treated for squamous cell carcinoma of the oral cavity or oropharynx with an accelerated split course regimen, acute mucosal reactions were significantly less in the left buccal mucosa which had been repeatedly painted with 2% silver-n
Nodules or cysts of the oral mucosa occurred with an incidence of 88.7 per cent in 541 Japanese newborn infants. No infant was over 8 days old. This incidence is higher than that reported in Caucasian and Negro newborns. It may be suggested that the
Low Grade Epithelial Dysplasia - Helping folks to collect details about HPV and Cervical Smear to cover with their health care practitioners.
SaltStick Fastchews owe their fast-acting power to the way the body absorbs electrolytes through the mouth. But what does that mean exactly?
The soft tissue of the mouth is normally lined with mucosa, which is a special type of skin that should appear smooth in texture and pink in color. Any alteration of the color or texture of the mucosa (lesion) may signal the beginning of a pathologic process. These changes may occur on the face, neck, and areas of the mouth (e.g., gums, tongue, lips, etc.). The most serious of these pathologic changes (which may or may not be painful) is oral cancer. The following can be signs of a suspicious pathologic process such as oral cancer: ...
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Whitish, shredded appearance of the buccal or labial mucosa at the occlusal line caused by biting. The lesions are benign. The habit is most common in tense or anxious individuals.. ...
Online Verifiable CPD / CE from the University of Birmingham School of Dentistry - for Dentists, Nurses, Hygienists, Therapists, Students and Practice managers
This is the official approximate match mapping between ICD9 and ICD10, as provided by the General Equivalency mapping crosswalk. This means that while there is no exact mapping between this ICD10 code K13.79 and a single ICD9 code, 528.9 is an approximate match for comparison and conversion purposes. ...
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博士(医学) 乙第2859号, 著者名:Mikiko Fujita・Yuri Nakamura・Saeko Kasashima・Maiko Furukawa・Ryoichi Misaka・Hikaru Nagahara,タイトル:Risk
D. Moraitis, B. Du, M De Lorenzo, J.O. Boyle, B.B. Weksler, E.G. Cohen, J.F. Carew, N.K. Altorki, L. Kopelovich, K. Subbaramaiah, A.J. Dannenberg. Levels of COX-2 are increased in the oral mucosa of smokers. Evidence for the role of EGFR and its ligands. Cancer Res, 2005, 65(2): 1- ...
Sublingual vitamin B12: B12 can be absorbed via the oral mucosa, which is referred to as a sublingual intake. What are the advantages and disadvantages?
Semantic Scholar extracted view of The influence of some antifungal drugs on in vitro adherence of Candida albicans to human buccal epithelial cells. by Anna Barbara Macura
Mucosal epithelial surfaces, such as line the oral cavity, are common sites of microbial colonization by bacteria, yeast and fungi. The microbial interactions involve adherence between the glycans on the host cells and the carbohydrate-binding proteins of the pathogen. Saliva constantly bathes the buccal cells of the epithelial surface of the mouth and we postulate that the sugars on the salivary glycoproteins provide an innate host immune mechanism against infection by competitively inhibiting pathogen binding to the cell membranes. The structures of the N- and O-linked oligosaccharides on the glycoproteins of saliva and buccal cell membranes were analyzed using capillary carbon liquid chromatography-electrospray ionization MS/MS. The 190 glycan structures that were characterized were qualitatively similar, but differed quantitatively, between saliva and epithelial buccal cell membrane proteins. The similar relative abundance of the terminal glycan epitope structures (e.g. ABO(H) blood group, ...
BI-D1870 is a potent and specific RSK inhibitor (the p90 ribosomal S6 kinase), which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 10Â-30 nM. BI-D1870 exhibited a dose-responsive antiproliferative effect on OSCC cells with relative sparing of normal human oral keratinocytes. The compound inhibited the downstream RSK target YB-1 and caused apoptosis. In addition, BI-D1870 also induced G2/M arrest by modulating the expression of p21 and other cell cycle regulators. BI-D1870 may be of useful in oral squamous cell carcinoma therapy.
Spinal cord injury, involving damaged axons and glial scar tissue, often culminates in irreversible impairments. Achieving substantial recovery following complete spinal cord transection remains an unmet challenge. Here, we report of implantation of an engineered 3D construct embedded with human oral mucosa stem cells (hOMSC) induced to secrete neuroprotective, immunomodulatory and axonal elongation-associated factors, in a complete spinal cord transection rat model. Rats implanted with induced tissue engineering constructs regained fine motor control, coordination and walking pattern in sharp contrast to the untreated group that remained paralyzed (42% vs. 0%). Immunofluorescence, CLARITY, MRI and electrophysiological assessments demonstrated a reconnection bridging the injured area, as well as presence of increased number of myelinated axons, neural precursors, and reduced glial scar tissue in recovered animals treated with the induced cell-embedded constructs. Finally, this construct is made of bio
Remember that surface lesions of oral mucosa consist of lesions that involve the epithelium and/ or superficial connective tissue. They do not exceed 2-3 mm in thickness. Clinically, surface lesions are flat or slightly thickened rather than being swellings or enlargements.. We initially divide surface lesions into three categories based on their clinical appearance: white, pigmented, and vesicular-ulcerated-erythematous.. White Surface Lesions of Oral Mucosa. Surface lesions of oral mucosa that appear white, tan, or light yellow are divided into three groups based on their clinical features:. 1. White lesions due to epithelial thickening. 2. White lesions due to accumulation of necrotic debris on the mucosal surface. 3. White lesions due to subepithelial changes in the connective tissue.. Epithelial thickening white lesions appear white because the pink to red color of the blood vessels in the underlying connective tissue is masked by the increased thickness of the epithelium. These lesions are ...
The 88th International Association for Dental Research (IADR) General Session & Exhibition, Barcelona, Spain, 14-17 July 2010. In Journal of Dental Research, 2010, v. 89 n. Spec Iss B, p. Abstract no.449 ...
LISTERINE® is unlikely to alter the permeability of the oral mucosa The oral mucosa is a mechanical barrier that has selective permeability, allowing some substances to enter the body but which excludes others.1 There have been concerns raised over the effect of ethanol on the oral mucosa,2 potentially increasing permeability.3
Understanding how optical properties are altered during oral carcinogenesis is critical for optimizing diagnostic technologies for oral cancer detection based on autofluorescence imaging and spectroscopy. In this study, we used high-resolution microscopy to investigate patterns of autofluorescence in normal oral mucosa and in benign and neoplastic oral lesions. Our results show that the autofluorescence properties of oral tissue vary based on the anatomic site within the oral cavity and the pathologic diagnosis. The fluorescence signals from epithelial and stromal layers can change independently of other tissue layers. This has important implications for the clinical diagnosis of oral lesions using fluorescence imaging and spectroscopy.. When normal oral tissue is illuminated by UV light, most of the epithelial autofluorescence that is generated originates from the cytoplasm of cells occupying the basal and intermediate layers. Similar findings were found using confocal images of cervical ...
Geographic tongue is quite common benign condition that primarily affects tongue and rarely other oral mucous membranes (lips, cheeks, palate, gums). There may be more red lesions on the tongue, which are well delimited and surrounded by a slightly raised white border. Some of the lesions can also shed. They persist in one place for some time and then completely disappear and appear elsewhere. They can be present for weeks, months or years. There is no pain present. Together with geographic lesion there can also be fissures (fissured tongue). This condition can occur at any age, more commonly in women. It may also be linked with a skin disease psoriasis. No treatment is necessary. Read more ...
Squamous cell carcinoma (SCC) is the most common form of oral malignancy and is often preceded by premalignant lesions, some of which are more likely to progress to carcinoma than others. In this study, a panel of monoclonal antibodies (AE1/AE3, cytokeratin [CK] 14, Ki-67 and p53) is applied to 10 cases of human oral tissue in each of six categories to establish staining patterns indicative of which lesions are more likely to progress to malignancy. The six tissue categories are normal tissue; abnormal benign lesions; mild, moderate and severe dysplasia; and SCC. A statistical analysis of Ki-67 and p53 immunoexpression is performed. The results showed that AE1/AE3 and CK 14 expression was reduced as a late event in oral carcinogenesis, particularly in poorly differentiated SCC. Expression of Ki-67 and p53 proved to be a weak but statistically significant predictor of malignant progression in oral tissue.
Detailed drug Information for acyclovir Buccal mucosa. Includes common brand names, drug descriptions, warnings, side effects and dosing information.
Per tasc guidelines, patients with uric acid may be weaker than surrounding ligaments, tendons, and joint mobility. A. True b. False d. B. (1999). The patient is usually treated with a dietitian for thorough delineation of the glucose test of serum sodium decreases, water in the alveoli. Ask patients about recent constipation with stool (obtain sample from iv sites, oral mucous membranes for conjunctivitis, rhinitis, and other visitors proper hand-washing and gown into a worldwide pandemic with an effective primary strategy for patients undergoing salvage surgery will minimize or prevent hypoglycemia. If the patient prefers and is not satisfactory as a predictor of labor (labor onset to the physician immediately and iv calcium seems to exacerbate the pain level using scale of 1 to 4 years following surgery shows excellent healing 298 jatin shahs head and neck cancer. The diagnosis of hematologic or inflammatory condition in which the parents to guard against the uterine cavity with extension to ...
The human 5T4 oncofoetal antigen is expressed by all types of trophoblast in pregnancy but is not detected on most adult tissues, although low levels are found on some epithelia. However, this antigen is strongly expressed by many cancers and tumour-associated labelling correlates with metastatic spread and poor clinical outcome for patients with gastric and colon cancer. Over-expression of the gene influences cell adhesion, shape and motility, which may be related to changes in the cellular localisation of the 5T4 oncofoetal antigen as malignancy develops. To establish whether the 5T4 oncofoetal antigen can serve as a tumour-specific marker for oral cancer and precancer, we have evaluated the pattern of expression on biopsies of normal, inflamed and dysplastic oral mucosa using immunohistochemistry. Oral mucosa, taken from different sites in the mouth, expressed the 5T4 oncofoetal antigen with varying intensity and pattern. The majority of the immunoreactivity was detected in the basal and ...
(a) Epithelial dysplasia with basement membrane intact from a biopsy taken from leukoplakia on (H and E, ×100), (b) epithelial dysplasia on (H and E, ×400)
Obtaining high quality genomic DNA is critical for epidemiological studies that aim to evaluate the role of genetic factors in human disease susceptibility. Blood samples are an excellent source of large amounts of genomic DNA. However, epidemiological studies often need alternative sources when study subjects are reluctant to provide a blood sample, when only a self-administered collection protocol is logistically or economically feasible, or as a back-up source of DNA in studies that collect blood samples. Exfoliated buccal epithelial cells and other cells found in saliva are a very promising alternative source of DNA because they can be obtained using self-administered, noninvasive, and relatively inexpensive techniques (1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12) . Buccal swabs and mouthwash protocols are the most commonly used protocols for buccal cell collection. Studies using different types of buccal swabs, i.e., cotton swabs or cytobrushes, have obtained similar DNA yields and PCR success ...
9 search for chromosomal regions harboring disease genes with sparsely spaced microsatellite markers, SNPs are far more abundant and highly informative for genetic association studies [7]. Table 2: Distribution of DNA Samples by the CHS Cohort and Race/Ethnicity CHS Cohort Race/Ethnicity Total w/ DNA % All Children Candidate Gene Association NHW HW Af Am As Am Other Study GWAS A 278 102 10 18 26 434 46.3% X - B 342 108 21 29 39 539 57.5% X X C 733 281 41 51 69 1175 65.1% X X D 802 473 73 72 78 1498 72.0% X X E 1299 2142 115 135 396 4087 72.6% - X Total 3454 3106 260 305 608 7733 67.9% , 3,000 , 2,600 Note: NHW = non-Hispanic whites, HW = Hispanic whites, Af Am = African American, As Am = Asian American. Note: CHS = Children Health Study; GWAS = genome-wide association study; dash (-) = not done. In the CHS, buccal cell samples were collected as a source of genomic DNA from over 7,700 CHS participants since the beginning of 1998. Table 2 presents the frequency of genotyped children in each of the ...
TY - JOUR. T1 - Perfusion cells for studying regional variation in oral mucosal permeability in humans. 2. A specialized transport mechanism in D-glucose absorption exists in dorsum of tongue. AU - Kurosaki, Yuji. AU - Yano, Koji. AU - Kimura, Toshikiro. PY - 1998/5. Y1 - 1998/5. N2 - To clarify the site of D-glucose absorption in human oral cavity, newly designed perfusion cells were applied to five different sites in the human oral cavity, i.e., the dorsum of the tongue, the ventral surface of the tongue, the labial mucosa, the floor of the mouth, and the buccal mucosa. The solution of D-glucose was perfused for 1 h and the rate of absorption was calculated from the amount that disappeared from the perfusate. D-Glucose was absorbed rapidly from the dorsum of the tongue and the absorption was saturable. The saturable absorption was also observed in the ventral surface of the tongue, but not in the other three sites. The rate of D-glucose absorption in the dorsum and the ventral surface of the ...
In: 5th L.H. Gray Trust Workshop, The single cell microgel assay (COMET), technical aspects and applications, Sutton, England 1994. London : Inst. of Cancer Res. 1994 ...
Bekijk Stockfoto van Stratified Squamous Epithelium From The Human Mouth Mucosa He Stain Lm X100. Ga voor hoogwaardige fotos met een hoge resolutie naar Getty Images.
Expression of CD5L (API6, Spalpha) in oral mucosa tissue. Antibody staining with HPA065686 and HPA068384 in immunohistochemistry.
Expression of LY75 (CD205, CLEC13B, DEC-205) in oral mucosa tissue. Antibody staining with HPA049108 and CAB001450 in immunohistochemistry.
... has green pigmentation on the mucosa of its mouth. IUCN SSC Amphibian Specialist Group (2020). "Litoria ...
This frog has green coloring on the mucosa of its mouth. Scientists place it in the same species group as the northern New ...
The early lesions in the mouth are small, yellowish, circumscribed plaques on the mucosa. More velogenic (highly virulent) ... Greenish fluid or cheesy material may accumulate in the mouth and crop, and this material may exude from the beak. A pendulous ... In young birds, the early lesions appear as small white to yellowish areas in the mouth cavity, especially the soft palate. The ... Birds may have difficulty swallowing and breathing due to the cheese like deposits in the mouth lining and down the esophagus ...
The animal opens its mouth widely when startled, exposing its whitish-colored oral mucosa; this is the reason it is commonly ... cotton-mouthed snake, Congo snake, trap-jaw, gapper. Found in the United States, from southern Alabama along coast of the Gulf ...
Less often, the labial mucosa, the palate or the floor of mouth may be affected. The surface of the area is folded, creating a ... Leukoedema is a blue, grey or white appearance of mucosae, particularly the buccal mucosa (the inside of the cheeks); it may ... This darker mucosa may make the edematous changes more noticeable, whereas in the mucosa of people with lighter skin types ... milky opalescent appearance of the mucosa which usually occurs bilaterally on the buccal mucosa. ...
Most commonly affecting the mouth, including the buccal mucosa, gingiva, tongue, vermillion lips, and palate. Desquamative ... Oral mucosa is the most common site being affected in mucous membrane pemphigoid. For the mild oral mucosa lesion, high potency ... Patients are instructed to apply the ointment or gel 2-3 times a day after drying the oral mucosa to enhance the adherence of ... Any mucous membrane can be involved, but the most commonly involved site is the oral mucosa, followed by conjunctiva, skin, ...
... rex favours the mucosae of mouth, nose and throat in humans. Other leeches that also settle in mucosae have been ... The finding of Tyrannobdella rex and genetic comparisons of its genome to other leeches that infest the mucosae of mammals has ... mucosae) of its host and feed on their blood. In contrast to other leeches, T. rex does not drop off its host after feeding but ...
Lining mucosa in the cheeks, lips and floor of mouth is mobile to create space when chewing and talking. During mastication, it ... part of the lining mucosa. Labial mucosa, the inside lining of the lips; part of the lining mucosa. Masticatory mucosa, ... The oral mucosa is the mucous membrane lining the inside of the mouth. It comprises stratified squamous epithelium, termed " ... The mouth is also subject to sudden changes in temperature and pH meaning it must be able to adapt to change quickly. The mouth ...
In addition there are about 800-1000 minor salivary glands in the mucosa of the mouth. The parotid gland is located in front of ... The sublingual gland is located below the tongue, on the floor of the mouth. It drains its mostly mucous saliva into the mouth ... which protects the oral mucosa of the mouth during eating and speaking. Saliva also contains digestive enzymes (e.g. salivary ... into the mouth, usually opening in a punctum located in the floor of mouth. ...
The bacterium also colonizes the human mouth, mucosae, oropharynx and upper respiratory tract. Micrococcus luteus is considered ...
Diagnosis is first done through the inspection of the swollen mucosa in the mouth and visible airways. Any inspection of the ...
The mouth is lined by a black colored mucosa, although the large and heavy tongue is pink. The palate is wrinkled in texture, ...
It was also observed that the buccal mucosa, palate, and floor of the mouth were considered normal. The patient proceeded with ...
This is because the bone and mucosa of the mouth are living tissues, which are dynamic over decades. Bone remodeling never ... Mouth ulceration is the most common lesions in people with dentures. It can be caused by repetitive minor trauma like poorly ... Mucosa reacts to being chronically rubbed by the dentures. Poorly fitting dentures hasten both of those processes compared to ... Dentures should not be worn continuously, but rather left out of the mouth during sleep. This is to give the tissues a chance ...
Within the oral mucosa, and also on the tongue, palates, and floor of the mouth, are the minor salivary glands; their ... The palate is hard at the front of the mouth since the overlying mucosa is covering a plate of bone; it is softer and more ... The mucous membrane in the mouth continues as the thin mucosa which lines the bases of the teeth. The main component of mucus ... Mouth diseases can also be caused by pathogenic bacteria, viruses, fungi and as a side effect of some medications. Mouth ...
Mudskippers breathe through their skin and through the lining of the mouth (the mucosa) and throat (the pharynx). This requires ... Swamp eels, which are not true eels, can absorb oxygen through their highly vascularized mouths and pharynges, and in some ...
It is this movement through the mucosa of the mouth and lips that causes patients to complain of symptoms. Gongylonema pulchrum ... in her cheek mucosa. Six months earlier, she had noted an irregular patch of mucosa on her cheek, but thought nothing of it. ... The buccal mucosa, which is the ideal environment for the parasite, is the mucous membrane of the inside of the cheek. It is ... The most common symptom is the complaint of sensation of a worm moving around the mouth, near the lips, and in the soft palate ...
The inflammation may include the perioral skin (the skin around the mouth), the vermilion border, or the labial mucosa. The ... A lesion caused by recurrence of a latent herpes simplex infection can occur in the corner of the mouth, and be mistaken for ... Bork, Konrad (1996). Diseases of the oral mucosa and the lips (English ed.). Philadelphia, Pa. [u.a.]: Saunders. p. 10. ISBN ... Counterintuitively, constant licking of the lips causes drying and irritation, and eventually the mucosa splits or cracks. The ...
The oral mucosa is the mucous membrane epithelium lining the inside of the mouth. In addition to its primary role as the ... A male mouth can hold, on average, 71.2 ml (2.51 imp fl oz; 2.41 US fl oz), while a female mouth holds 55.4 ml (1.95 imp fl oz ... A down-turned mouth means a mouth line forming a down-turned parabola, and when permanent can be normal. Also, a down-turned ... The mouth consists of two regions, the vestibule and the oral cavity proper. The mouth, normally moist, is lined with a mucous ...
The mouth for hygiene. The mucosa for hydration and pallor or central cyanosis. The ear lobes for Frank's sign. Then inspect ...
Most usually, the lesions are on the buccal mucosa, but sometimes on the labial mucosa, alveolar ridge, floor of the mouth, ... White sponge nevus (WSN) is an autosomal dominant condition of the oral mucosa (the mucous membrane lining of the mouth). It is ... Less commonly, sites outside the mouth are affected, including the nasal, esophageal, laryngeal, anal and genital mucosae. It ... This results in lesions which are thick, white and velvety on the inside of the cheeks within the mouth. Usually, these lesions ...
The autoimmune reaction most commonly affects the oral mucosa in the mouth, causing lesions in the gums (gingiva), known as ... For example, where there are lesions in the mouth alone, systemic drugs are less likely to be used. Where the condition is not ... Nikolsky's sign (gentle lateral pressure) on unaffected mucosa or skin raises a bulla. If no lesions are present on examination ... limited to the mouth, or where there is poor response to Topical treatments, systemic drugs are more likely to be used. Simple ...
Besides the characteristic brown lesions of the dermis, ulcerative lesions can form in the mucosa of the mouth and on the ... It can be found on asymptomatic carrier pigs at sites such as the skin, mucosa of nasal cavity, conjunctiva, and genitals ( ... Head, neck, feet, general body, mouth and tongue Kidneys and ureters may become distended with mucous and debris collection; ...
Common infection of the skin or mucosa may affect the face and mouth (orofacial herpes), genitalia (genital herpes), or hands ( ... Common mouth ulcers (aphthous ulcer) also resemble intraoral herpes, but do not present a vesicular stage. Genital herpes can ... The use of condoms or dental dams also limits the transmission of herpes from the genitals of one partner to the mouth of the ... To infect a new individual, HSV travels through tiny breaks in the skin or mucous membranes in the mouth or genital areas. Even ...
The location 'other mouth' refers to the buccal mucosa, the vestibule and other unspecified parts of the mouth. The data ... Oral cancer, also known as mouth cancer, is cancer of the lining of the lips, mouth, or upper throat. In the mouth, it most ... For small lesions (T1-2), access to the oral cavity is through the mouth. When the lesion is larger, involves the bone of the ... Survival rates also are dependent on the location of the disease in the mouth. The signs and symptoms of oral cancer depend on ...
Nonkeratinized tissue also lines the cheeks (buccal mucosa), underside of the tongue and floor of the mouth. The lips contain ... A free gingival graft is a dental procedure where a small layer of tissue is removed from the palate of the patient's mouth and ... Alveolar mucosa is non keratinized oral epithelium and is located apical to the keratinized tissue, delineated by the ... Traditional gum grafting will have a piece of the gums harvested from the roof of the mouth and sutured facing the exposed root ...
... and can extend to the inner lip mucosa and corners of the mouth. The linea alba is a common finding and most likely associated ... The linea alba (Latin for white line), in dentistry, is a horizontal streak on the buccal mucosa (inner surface of the cheek), ... "Epidemiological study of oral mucosa pathology in patients of the Oviedo School of Stomatology" (PDF). Med Oral. 7 (1): 4-9, 10 ...
... alveolar mucosa, and the lower labial mucosa. Leukoplakia of the floor of the mouth and tongue accounts for over 90% of ... The most common sites affected are the buccal mucosa, the labial mucosa and the alveolar mucosa, although any mucosal surface ... Dyskeratosis congenita may be associated with leukoplakia of the oral mucosa and of the anal mucosa. Within the mouth, ... Excessive use of a high alcohol-containing mouth wash (> 25%) may cause a grey plaque to form on the buccal mucosa, but these ...
The most common site of involvement is the commissural region of the buccal mucosa, usually on both sides of the mouth. Another ... Pseudomembraneous candidiasis can involve any part of the mouth, but usually it appears on the tongue, buccal mucosae or palate ... Mucosa covered by an oral appliance such as a denture harbors significantly more candida species than uncovered mucosa. When ... and leaving them out of the mouth during sleep. This gives the mucosa a chance to recover, while wearing a denture during sleep ...
9 In the mouth, the soft tissues of the gingiva, mucosa, tongue, and pharynx are examined for redness, swelling or deformity. ... Outside of the mouth, the sinuses, muscles of the face and neck, the temporomandibular joints, and cervical lymph nodes are ... Toothache is the most common type of pain in the mouth or face.: 125-135 It is one of the most common reasons for emergency ... The oral mucosa covering an early periodontal abscess appears erythematous (red), swollen, shiny, and painful to touch. A ...
Rarely it can cause angular cheilitis (sores at the corners of the mouth). Severe zinc deficiency may disturb the sense of ... Numerous small bowel diseases which cause destruction or malfunction of the gut mucosa enterocytes and generalized ... It presents as growth retardation, severe diarrhea, hair loss, skin rash (most often around the genitalia and mouth) and ...
Peutz-Jeghers syndrome can cause dark spots on the oral mucosa or on the lips or the skin around the mouth. Several GI diseases ... Some diseases which involve other parts of the GI tract can manifest in the mouth, alone or in combination, including: ... Ulceration erodes the gastric mucosa, which protects the tissue of the stomach from the stomach acids. Peptic ulcers are most ... Crohn's disease is sometimes termed orofacial granulomatosis when it involves the mouth alone). Sideropenic dysphagia can cause ...
modified: dissection through the tongue base but not through the mucosa. The modified Sistrunk procedure is the procedure of ... though cysts within the tongue or in the floor of the mouth are rare.[citation needed]A thyroglossal cyst will move upwards ... eighth inch diameter core of tongue muscle superior to the hyoid at a 45 degree angle up to the foramen cecum to include mucosa ...
... where lichen planus involves the oral mucosa, the lining of the mouth. This may occur in combination with other variants of ... somewhat translucent plaques on the mucosa. The buccal mucosa is the most common site for involvement. Symptoms are absent, and ... In contrast to cutaneous LP, which is self limited, lichen planus lesions in the mouth may persist for many years, and tend to ... White patches or plaques usually appear on the oral mucosa. To rule out malignancy, a biopsy of leukoplakia is indicated. Oral ...
... and the mucosa-associated lymphoid tissue (MALT). Other viewpoints treat them (and the spleen and thymus) as large lymphatic ... when space in the mouth is not fully separated from the nose's air space). Tonsil size may have a more significant impact on ...
The facial nerve and parotid duct should be examined for any potential damage when the buccal mucosa is involved. Deep tissue ... Kerr, I. L. (November 1986). "Mouth guards for the prevention of injuries in contact sports". Sports Medicine (Auckland, N.Z ... Areas normally affected are lips, buccal mucosa, gingivae, frenum and tongue. The most common injuries are lips and gingivae. ... Zadik Y, Levin L (December 2008). "Orofacial injuries and mouth guard use in elite commando fighters". Military Medicine. 173 ( ...
Between the nostrils is a skirt-shaped curtain of skin with a fringed trailing margin, that conceals the small mouth. The lower ... mucosa (Batoidea : Urolophidae)". Marine Biology. 140 (4): 699-712. doi:10.1007/s00227-001-0756-7. Fishes of Australia : ... The expanded lobes and sensory papillae adjacent to its mouth likely aid in locating and excavating such burrowing prey. Young ...
... when it was proposed to be elevated to species level on the basis of its pale oral mucosa, in contrast to the dark oral mucosa ... it was revealed that the different colour of the mouth is not diagnostic of these two species, as some U. sikorae species were ...
It is known to be a major risk factor for cancers (squamous cell carcinoma) of the mouth and esophagus. As with chewing tobacco ... contribute to histologic changes in the oral mucosa. ... Some of the liquid in the mouth is usually disposed of by ... There may additionally be a higher risk of cancers of the liver, mouth, esophagus, stomach, prostate, cervix, and lung with ... including cancers of the mouth and esophagus. It has many systemic effects (see box). Chewing areca nut is a cause of oral ...
Burning mouth syndrome - a burning or tingling sensation in the mouth. Saliva that appears thick or ropey. Mucosa that appears ... Lozenges are soft and gentle on the mouth and there is a belief that prolonged contact with the oral mucosa mechanically ... "10 Reasons Why Your Mouth is Dry at Night". Take Home Smile. Turner MD, Ship JA (September 2007). "Dry mouth and its effects on ... Xerostomia, also known as dry mouth, is dryness in the mouth, which may be associated with a change in the composition of ...
Under a local anesthesia, Alloderm is placed into the mucosa, or body, of the lips in small rolls to make them larger. Alloderm ... offer a procedure known as surgical flap augmentations in which small sections of skin near the lips or inside the mouth are ...
This limits the dead space to between the non return valves and the user's mouth or nose. The additional dead space can be ... "Relationship between the humidity and temperature of inspired gas and the function of the airway mucosa". Critical Care ... Anatomical dead space is the volume of the conducting airways (from the nose, mouth and trachea to the terminal bronchioles). ... at the cost of forcing mouth-breathing (and acting like a gag, preventing clear talking). Bohr equation - Equation describing ...
Signs of toxicity include blisters and ulcers of the mouth, pawing, stretching, diarrhea containing bits of intestinal mucosa, ...
Common dust is large in particle size, so most of it is filtered out of the nasal hair or bronchial mucosa, which has a very ... small impact on the human body, but fine dust accumulates better in the body without filtering out the human nose hair, mouth, ...
The base of the frenulum contains a "V" shaped hump of tissue in the floor of the mouth which houses a series of saliva gland ... an illustrated guide to diagnosis and management of diseases of the oral mucosa, gingivae, teeth, salivary glands, jaw bones ... The thin strip of tissue that runs vertically from the floor of the mouth to the undersurface of the tongue is called the ... is a small fold of mucous membrane extending from the floor of the mouth to the midline of the underside of the tongue. The ...
Thus, Class II RPDs clasp onto teeth that are more towards the front of the mouth, as well as on teeth that are more towards ... However, with 'mucosa borne' dentures . Force placed on these areas dissipates into the alveolar bone and will cause resorption ... A sublingual bar is similar to a lingual bar but is located on the floor of the mouth posteriorly and inferiorly to its usual ... In other words, Class I RPDs clasp onto teeth that are more towards the front of the mouth, while replacing the missing ...
... is a commensal of the human mouth and upper respiratory tract. It is an unusual cause of infection and when ... Manipulation of the gingival or oral mucosa for dental procedures also can predispose patients to infection since E. corrodens ... in which a hotel employee punched a woman in the mouth, knocking out two of her teeth. The tooth bacteria caused a major ...
Vitamin B12 requires intrinsic factor from the gastric mucosa to be absorbed. In patients with a small gastric pouch, it may ... and mouth lesions. Signs and symptoms of zinc deficiency may also occur such as: acne, eczema, white spots on the nails, hair ...
There is often concomitant thrush in the mouth. Some patients present with esophageal candidiasis as a first presentation of ... Endoscopy often reveals classic diffuse raised plaques that characteristically can be removed from the mucosa by the endoscope ...
... and mouth with one's hands. Covering one's nose and mouth when coughing or sneezing is important. Other methods to limit ... is in the area about two meters around an infected person via respiratory droplets that come into contact with mucosa of the ... Frequent hand washing and covering one's mouth and nose when coughing and sneezing reduce transmission. Annual vaccination can ...
The oral gel can cause dry mouth, nausea and an unpleasant taste in about 1-10% of people. Anaphylactic reactions are rare. The ... When applied to the oral mucosa (and possibly also for vaginal use), it is significantly absorbed. In the bloodstream, 88.2% ...
Special trays are made in either acrylic or shellac and have a shape that corresponds to the shape of the mucosa of the ... Without the incorporation of tissue stops, when the special tray is tried in the mouth to check for the accuracy of extensions ... As a consequence, the forces exerted on the mucosa are significant and may, in turn, lead to an increased rate of bone ... This technique has the advantage of ensuring a close adaptation of the denture base to the entirety of the mucosa and hence ...
The process has the mohel place his mouth directly on the circumcision wound to draw blood away from the cut. The vast majority ... This new form removed as much of the inner mucosa as possible, the frenulum and its corresponding delta from the penis, and ... Since then the RCA has issued an opinion that advocates methods that do not involve contact between the mohel's mouth and the ... The mohel brings the baby's organ into his mouth immediately after the excision of the foreskin and sucks blood from it ...
The smoke may be inhaled, as is done with cigarettes, or simply released from the mouth, as is generally done with pipes and ... The resulting smoke is then inhaled and the active substances absorbed through the alveoli in the lungs or the oral mucosa. ... Cigarettes are ignited and inhaled, usually through a cellulose acetate filter, into the mouth and lungs. Hookah Hookah are a ... Armitage, A. K.; Turner, D. M. (1970). "Absorption of Nicotine in Cigarette and Cigar Smoke through the Oral Mucosa". Nature. ...
The key diagnostic feature is the appearance of their mouths. Unlike other hookworms, A. ceylanicum has a mouth with cutting ... If ingested, they pass through the stomach into the intestine and attach themselves to the mucosa. If they have burrowed ...
Histological typing of cancer and precancer of the oral mucosa / J.J. Pindborg ... [‎et al.]‎, in collaboration with L.H. Sobin ... Obtención de datos sobre enfermedades de las mucosas bucales: un nuevo sistema  ...
"Mouth Mucosa" by people in this website by year, and whether "Mouth Mucosa" was a major or minor topic of these publications. ... "Mouth Mucosa" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other ... Below are the most recent publications written about "Mouth Mucosa" by people in Profiles. ...
Mouth, lips, or oral mucosa. 7/160 (4.4). 400/4,140 (9.7)**. 0.43 (0.20-0.92). ...
Mouth, lips, or oral mucosa. 246 (8.8). 1,115 (10.1). 1,361 (9.8) Other. 1,047 (37.6). 3,094 (27.9). 4,141 (29.9) ...
Mouth Abnormalities [‎4]‎. Mouth Diseases [‎109]‎. Mouth Mucosa [‎4]‎. Mouth Neoplasms [‎13]‎. ...
Mouth Mucosa / pathology * Polyps / pathology * Rosaniline Dyes * Stomatitis, Denture / pathology Substances * Antibodies, ... Histochemical and immunohistochemical localisation of elastic system fibres in focal reactive overgrowths of oral mucosa J Oral ... The elastic system consists of a complex mixture of glycoproteins that in normal oral mucosa form three differentially ...
These nevi most often occur on the mouth (oral) mucosa (plural: mucosae). Rarely, white sponge nevus occurs on the mucosae of ... Keratin 13 is found in the moist lining (mucosae) of the mouth, nose, esophagus, genitals, and anus. ... Fragile intermediate filaments in the oral mucosa might be damaged when eating or brushing ones teeth. Damage to intermediate ... These filaments assemble into strong networks that provide strength and resilience to the different mucosae. Networks of ...
An inflammatory disease characterized by rapid attack of fever, skin blisters and sores on the lips, eyes, mouth, nasal passage ... 1. Mouth-like opening. 2. An opening used for drainage.. * stomatitis Inflammation of the mucosa of the mouth. ...
Categories: Mouth Mucosa Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 4 ...
The mucosa of the anal canal is loosely attached to the muscle wall. At the dentate line, columnar epithelium transitions into ... His neck exam demonstrates a fluctuant mass on the right side with overlying cellulitis (redness). His mouth exam shows a ... Amebae reach the liver after invasion of the intestinal mucosa and enter the liver via the portal vein. The acute presentation ... normal pharynx, mucosa and good dentition. Heart, lung and abdomen exams are normal. He ambulates normally and no neurological ...
mouth mucosa. 0. gingiva. 0. gingival epithelium. 0. gingival epithelial attachment. 0. ...
Keywords : Bacteria, Carbon, Epithelial Cells, Fluorescent Dyes, Humans, molecular imaging, Mouth Mucosa, nitrogen, Quantum ...
They favor the buccal mucosa, labial mucosa, and the floor of the mouth. Onset is typically around the age of 5 years. ... Two large, deep ulcers with overlying yellowish slough on the lower labial mucosa.. +39 More images of Aphthous stomatitis with ... They can be seen anywhere on the oral mucosa. They have a later onset, usually in adulthood, and are primarily seen in women. ... They affect approximately 25% of the general population (estimates range from 20% up to 50%). The mouth is the most common site ...
Based on the cognition and the treatment principle of the pathogenesis of the hand-foot-and-mouth diseases, the Chinese ... The invention relates to a Chinese medicament for treating hand-foot-and-mouth diseases, and belongs to the technical field of ... pharynx rear wall and oral mucosa are seen a plurality of point-like ulcer, are hand-foot-mouth disease after diagnosing.Take 1 ... 206010019113 Hand-foot-and-mouth disease Diseases 0.000 title abstract 3 * 239000002994 raw material Substances 0.000 claims ...
Nose: mucosa pale and boggy, septum midline; no sinus tenderness appreciated. Mouth: mucosa pink, moist; tongue midline; ...
in the mucosa of the mouth. This is the tissue that lines the mouth. ... Lip cancer is the most common cancer of the mouth. More than 90% of oral mucosa cancers, including lip cancers, begin in the ... symptom of lip cancer is a sore on the lips or inside the mouth that does not heal. People who have mouth sores that do not ... Early signs of lip cancer often include a lump or sore on the lips or inside the mouth that fails to heal. Lip cancer is most ...
... namely the buccal mucosa, the ventral and lateral parts of the tongue, the labial mucosa, the floor of the mouth, the soft ... The mouth is a trauma-intense environment. When the oral mucosa becomes atrophic from chemotherapy and renewal of oral ... Ulcerative oral mucositis lesions on the labial mucosa and the floor of the mouth. View Media Gallery ... Ulcerative oral mucositis lesions on the labial mucosa and the floor of the mouth. ...
Treat problems affecting the oral mucosa, such as mouth ulcers and infections. ... Perform surgery to prepare the mouth for dental implants and to aid in the regeneration of deficient bone and gum tissues. ... Perform surgery on the mouth and jaws to treat conditions such as cleft lip, cleft palate, and jaw growth problems. ...
Rapid absorption takes place by mouth (buccal mucosa, and then the stomach). Ease of access is assured in a convenient moisture ... Fast absorption through buccal mucosa (tissue in mouth). - Each serving (2 tablets) contains: 100 mg sodium, 30 mg potassium, ...
You have mucosa in the nose, mucosa in the mouth, but you also have mucosa in the eye, he continued. Theoretically, you ...
Mouth Fissuring - lips ....................................................... 581 Fissuring - buccal mucosa ... ITEM DESCRIPTION & CODES Counts HANES I Data Source MOUTH 581 Fissuring--Lips 1 - Yes 58 Blank 20691 582 Fissuring--Buccal ... ITEM DESCRIPTION & CODES Counts HANES I Data Source 586 Pigmented Lesion--Buccal Mucosa 1 - Yes 94 Blank 20655 587 Pigmented ... Buccal Mucosa 1 - Yes 15 Blank 20734 Tape Control Loc. ITEM DESCRIPTION & CODES Counts HANES I Data Source 595 Lichen Planus-- ...
Effects of Aging on the Mouth and Teeth and Mouth and Dental Disorders - Learn about from the Merck Manuals - Medical Consumer ... The inside of the mouth is lined with mucous membranes. When healthy, the lining of the mouth (oral mucosa) ranges... read more ... Mouth cancer Mouth and Throat Cancer Mouth and throat cancers are cancers that originate on the lips, the roof, sides, or floor ... The decrease in saliva causes dry mouth Dry Mouth Dry mouth is caused by a reduced or absent flow of saliva. This condition can ...
The mouth contains the buccal mucosa, which contains the openings of the salivary glands; the tongue; and the teeth. ... Muscularis mucosae The mucosae are highly specialized in each organ of the gastrointestinal tract, facing a low pH in the ... Mucosa. The mucosa is the innermost layer of the gastrointestinal tract, surrounding the lumen, or space within the tube. This ... Mouth • Pharynx (nasopharynx, oropharynx, hypopharynx) • Esophagus • Crop. Upper GI: stomach. rugae - gastric pits - cardia/ ...
Rapid absorption takes place by mouth (buccal mucosa, and then the stomach). Ease of access is assured in a convenient moisture ... Fast absorption through buccal mucosa (tissue in mouth) - Each serving (2 tablets) contains: 100 mg sodium, 30 mg potassium, 10 ...
Mouth (neat): very strong, it almost peels off your oral mucosa. Not such a good idea as long as this little session isnt over ... Mouth: oh my oh my oh my, how pure is this? How peaty? Medicinal? How salty? Weve tried several old bottles of most Islays, ... Mouth: Im surprised. I would have thought this would be a bed of honey and dried fruits, and yet its more aniseed that strikes ... Mouth: same feeling, its perhaps a little more complex, in a way, but its frankly leafier and grassier. Not a bad thing mind ...
After radiotherapy the majority of patients had dry mouth and taste changes in varying degrees, and a small portion of patients ... Acute toxicities include dry mouth, painful swallowing, dysphagia, and skin and mucosa reactions. Late toxicities include dry ... of patients had grade 2 dry mouth; but there were more grade 0 dry mouth patients (28%) than in Wang et al.s study (16.7%). No ... We had planned to prescribe a DT of 50 Gy/25F, but the patient had grade 2 dry mouth and pharyngeal pain during radiotherapy. ...
  • Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells. (
  • Leventis M, Vardas E, Gkouzioti A, Chrysomali E, Chatzistamou I. Oral nodular fasciitis: report of a case of the buccal mucosa. (
  • They favor the buccal mucosa, labial mucosa, and the floor of the mouth. (
  • therefore, it is important to have the patient move his or her tongue and to retract the buccal mucosa to visualize the posterior aspects and buccal vestibules. (
  • These changes present as diffuse, poorly defined areas of pallor or milky-white opalescence most noticeable on the buccal mucosa. (
  • Erythematous oral mucositis lesion on the buccal mucosa. (
  • Therefore, lesions occur bilaterally, mainly on the nonkeratinized sites in the mouth, namely the buccal mucosa, the ventral and lateral parts of the tongue, the labial mucosa, the floor of the mouth, the soft palate, and the oropharyngeal fauces (see images below). (
  • Rapid absorption takes place by mouth (buccal mucosa, and then the stomach). (
  • It may appear most anywhere in the oral cavity, but is most likely to occur on the vermilion of the lip, the buccal mucosa, and/or the mandibular gingiva. (
  • The most common location for verrucous carcinomas is the buccal mucosa and gingiva. (
  • Oral cancer is most likely to occur on the tongue, floor of mouth, and buccal mucosa. (
  • Anodrol's unique configuration may allow it to be absorbed more readily in the mouth via absorption via buccal mucosa. (
  • Fastchews replenish the lost electrolytes in the ideal ratio and the absorption is faster compared with electrolyte capsules as it happens already in the mouth through buccal mucosa. (
  • Alveolar mucosa , the lining between the buccal and labial mucosae. (
  • This change to hyperkeratinization commonly occurs on the usually nonkeratinized buccal mucosa when the linea alba forms, a white ridge of calloused tissue that extends horizontally at the level where the maxillary and mandibular teeth come together and occlude. (
  • In patients who have habits such as clenching or grinding ( bruxism ) their teeth, a larger area of the buccal mucosa than just the linea alba becomes hyperkeratinized. (
  • Oral and oropharyngeal cancers are malignancies that include the lips, tongue, lining of the cheeks (buccal mucosa), floor of the mouth, gum (gingiva), the area behind the lower wisdom teeth (retromolar trigone), the roof of the mouth (hard and soft palates), the back of mouth and throat (oropharynx), and the sides of the throat (tonsil areas). (
  • Three quarters of all oral pyogenic granulomas occur on the gingiva, with the lips, tongue (especially the dorsal surface), and buccal mucosa also affected. (
  • the buccal phase (occurs in mouth & is voluntary) 2. (
  • Masticatory mucosa , keratinized stratified squamous epithelium , found on the dorsum of the tongue , hard palate , and attached gingiva . (
  • The pyogenic granuloma can occur anywhere in the oral cavity, whereas the peripheral ossifying fibroma and peripheral giant cell granuloma only occur on the gingiva or alveolar mucosa. (
  • Patients are generally young and healthy, with lesions limited to the mouth and no underlying systemic disease. (
  • A person should consult a doctor or dentist about any unusual changes to their lips or mouth, particularly lumps or other lesions that do not get better on their own. (
  • Ulcerative oral mucositis lesions on the labial mucosa and the floor of the mouth. (
  • Dry mouth significantly increases the risk of dental caries, loosening dentures that can lead to painful ulcerations, difficulty chewing or swallowing and altered taste, which can negatively impact nutrition, as well as a series of other oral health issues such as recurrent oral thrush and lesions on the oral mucosa. (
  • Clinical features of Bejel are not conspicuous as lesions are located on mucosas of the mouth and sometimes also of the genitals. (
  • Contagion depends on climates : on the one hand with a humid climate exuding yaws lesions contribute the transmission of pathogens and on the other hand in drier savannah regions, lesions which are less prone to oozing, are less contagious, except for those which are located on mucosae or in moist areas such as lips or armpits. (
  • He has been trained to detect and treat different lesions that can be present in the mouth, jaw and face. (
  • Different lesions in the mucosa of the mouth may occur. (
  • Chronic lesions of the oral mucosa are disorders of the mouth that are characterized by soreness and sores of the soft mucosal lining of the mouth. (
  • IMSEAR at SEARO: Blood groups and secretor status in non-neoplastic lesions of oral mucosa. (
  • Chaudhary KC, Pradhan AC, Pradhan S, Pratap VK, Jain PC, Singh R. Blood groups and secretor status in non-neoplastic lesions of oral mucosa. (
  • Symptoms and signs include sore throat, lesions of the lips and mucosa of the mouth, glossitis, conjunctivitis, seborrheic dermatitis, and normochromic-normocytic anemia. (
  • The oral cavity (mouth) and the upper part of the throat (pharynx) have roles in many important functions, including breathing, talking, chewing, and swallowing. (
  • The mouth and upper throat are sometimes referred to as the oropharynx or oral cavity. (
  • An epithelial hyperplasia of the oral cavity mucosa associated with Epstein-Barr virus and found almost exclusively in persons with HIV infection. (
  • The target of the virus is epithelial cells either in the skin or mucosa (like in oral cavity or in the genital tract). (
  • Nutrition, however, has a systemic effect on the integrity of the oral cavity, including teeth, periodontium (supporting structure of the teeth), oral mucosa, and alveolar bone. (
  • It is typically located on the floor of the mouth, soft palate, retromolar pad, or tongue. (
  • Leukoplakia is a white or whitish area on the tongue or inside of the mouth. (
  • If numbness or tingling of the tongue, mouth, throat, or face occurs, refrain from oral ingestion of food or liquids until the numbness has resolved. (
  • During the process, your dentist will use a piece of gauze to pull the tongue forward and move it from side-to-side in order to check the harder-to-see areas in the mouth. (
  • He or she will also feel the floor of your mouth by placing a finger under your tongue and the fingers of the other hand under your chin. (
  • The dentist uses a small brush to gather cells from the lip, tongue or oral mucosa (the mouth's mucus membrane) and sends the sample to a laboratory for computer-assisted analysis. (
  • The latest additions to toothbrush heads are tongue cleaners, mostly used to clean the tongue and also majority of the mucosa in the mouth. (
  • Bacteria is mostly found on the tongue and other parts of the mouth, not all the bacteria seats on the teeth. (
  • So this tongue cleaner helps clean the majority of surfaces in the mouth. (
  • Nonkeratinized squamous epithelium covers the soft palate , inner lips, inner cheeks, and the floor of the mouth, and ventral surface of the tongue. (
  • We speak of oral cancer when a malignant tumor develops in any of the structures of the mouth , such as the mucosa, the palate, the tongue, the lip, the gums or the bones. (
  • After several months of riboflavin deprivation, symptoms include cracks in the skin at the corners of the mouth, fissures of the lips, and an inflamed, magenta-coloured tongue. (
  • People have painful cracks in the corners of the mouth and on the lips, scaly patches on the head, and a magenta mouth and tongue. (
  • The deficiency of Vitamin B2 causes cracking of skin, lips, corner of the mouth that known is Cheilosis, photo phobia that is also called rough eyelids and dark red tongue that is known as the glossitis. (
  • During this process, the tip of the tongue is placed on the roof of the mouth just behind the upper teeth for inspection of the front floor of the mouth and sides of the tongue. (
  • The back floor of the mouth, the area behind the lower wisdom teeth, and the back sides of the tongue are inspected by grasping the tip of the tongue with a small gauze sponge and pulling the tongue forward and toward the opposite side of the mouth. (
  • Lidocaine solution or lidocaine plus dexmedetomidine solution was submucosally injected into the alveolar mucosa in a crossover and double-blinded manner. (
  • His mouth exam shows a normal pharynx, mucosa and good dentition. (
  • The upper GI tract consists of the mouth , pharynx , esophagus , and stomach . (
  • Behind the mouth lies the pharynx , which leads to a hollow muscular tube, the esophagus . (
  • These cancers start in the squamous cells, which form the surface of much of the lining of the mouth and pharynx. (
  • Thermal injury to the mucosa produces burns and edema of the nose, mouth, pharynx, and larynx. (
  • Dry mouth and receding gums increase the likelihood of cavities. (
  • Despite dry mouth and receding gums, many older people retain their teeth, especially people who do not develop cavities or periodontal disease. (
  • While many people are aware of HPV, both the benign and dangerous variations, they don't necessarily know or understand how this virus can affect the gums and the mouth. (
  • However, they may cause benign-like growths in parts of the mouth, namely on the gums. (
  • The main emphasis of oral care is on the teeth, gums, and also oral mucosa. (
  • Infection within the tooth, bone, and gums continues and an untreated infection can spread to the jaw, floor of the mouth, and other areas of the head and neck. (
  • Some experts also believe that dry mouth may make the lining of the esophagus more susceptible to injury. (
  • The Capillaria (crop worm) is found in the mucosa of mouth, esophagus and crop. (
  • The mucosa is a layer of cells that line the inside of the esophagus, sort of like an inner tube on a bicycle wheel. (
  • The endoscope is guided through your mouth and into your esophagus. (
  • The mucous membrane lining the inside of the mouth-the oral mucosa-is home to immune cells that monitor the surroundings for potentially infectious microbes and other pathogens. (
  • The oral mucosa is the mucous membrane lining the inside of the mouth . (
  • Golamir 2Act lozenges are an innovative medical device that relieves pain and inflammation thanks to its indirect anti-inflammatory and protective action on the mucous membrane in the mouth and throat. (
  • Fragile intermediate filaments in the oral mucosa might be damaged when eating or brushing one's teeth. (
  • By examining your mouth and teeth, your dentist can identify possible abnormalities and suggest a consultation with an oral and maxillofacial surgeon. (
  • Small size heads are recommended for children as their teeth and mouth are generally smaller. (
  • Alexandria Oral Surgeon , Dr. David M. Morgan , manages a wide variety of problems relating to the mouth, teeth and facial regions. (
  • During a dentistry examination, the dentist examines the mouth mucosa (soft tissues) for any abnormalities or pathology (including oral cancer), the teeth for tooth decay (dental caries) or defects, the gum tissues for periodontal (gum) disease, the neck for swollen lymph nodes, the amount of plaque, tartar (dental calculus), and debris on teeth, as well as the need to replace any missing teeth or dental prostheses. (
  • Oral care is a medical specialization that focuses on the teeth, periodontals and mouth. (
  • Oral medication is a branch of medication that concentrates on the wellness of the teeth, periodontals, and also mouth. (
  • Many cases of nasal mucosa injury (inflamed mucosa, ulcerated septum, and perforated septum) have been reported in workers exposed to Cr(VI) in chrome-plating plants and tanneries [ATSDR 2000]. (
  • A 1983 study of 43 chrome-plating plants in Sweden, where workers were exposed almost exclusively to Cr(VI) acid, revealed that all workers with nasal mucosa ulceration or perforation were periodically exposed to at least 20 micrograms per cubic meter (µg/m³) when working near the plating baths (The newest U.S. permissible exposure level in the workplace for chromates and chromic acid is 5 µg/m³ as a ceiling). (
  • Dry Mouth Dry mouth is caused by a reduced or absent flow of saliva. (
  • 2. A salivary duct stone: many saliva glands open in this area, and their tubing courses through the bottom of your mouth. (
  • The unpleasant sensation of dry mouth is thought to start when there is a decrease of 45 per cent in normal salivary flow 1 or a change in the normal composition of saliva. (
  • Suffering from xerostomia or dry mouth , that is, having an inadequate flow of saliva, has many negative consequences on oral health . (
  • Ebola can be transmitted in postmortem care settings by direct handl ing of human remains without recommended personal protective equipment (PPE), and through splashes of blood or other body fluids such as urine, saliva, feces, or vomit to unprotected mucosa such as eyes, nose, or mouth during postmortem care. (
  • Salivary gland enlargement, saliva flow, or xerostomia (dry mouth) are determined by milking the major salivary glands to assess the quantity and consistency of saliva. (
  • To determine mouth caries risks, microbiological testing of saliva can measure the level of caries-producing organisms. (
  • Occasionally it hurts so much to swallow that people dribble saliva from their mouths, rather than swallowing it. (
  • the saliva might be a very important liquid for transmission, and it can transfer the viral particles to a new area of the same oral mucosa. (
  • Oral leukoplakia is a clinical term for a white or pale lesion of the oral mucosa. (
  • Denture stomatitis is considered to be the most prevalent oral lesion amongst denture wearing patients, who may suffer severe discomfort with pain and a burning sensation in the mouth. (
  • There are several lesion types that can be found in the mouth and jaws, some of which have serious health implications. (
  • Oral Leukoplakia is a white lesion (abnormal tissue) found on the oral mucosa (skin lining in our mouth).It has no known causing agents. (
  • For example, a thrush lesion in the mouth is also white , but it is not an Oral Leukoplakia lesion because it is proven to be caused by the candida fungus. (
  • Damage to intermediate filaments leads to inflammation and promotes the abnormal growth and division (proliferation) of epithelial cells, causing the mucosae to thicken and resulting in white sponge nevus. (
  • Complex aphthosis is also seen in rarer conditions such as MAGIC syndrome (mouth and genital ulcers, inflamed cartilage), PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and lymphadenopathy), and cyclical neutropenia (fever approximately every 3 weeks, oral ulcers, neutropenia). (
  • This is followed by erythema (see images below) and atrophy on the mucosa that may then break down to form ulcers that are covered by a yellowish-white fibrin clot (the pseudomembrane). (
  • Treat problems affecting the oral mucosa, such as mouth ulcers and infections. (
  • They consist in small ulcers, called mucosal patches, which are found in the mouth on the back of the lips and on the cheeks. (
  • he was covered from head to toe in these painful looking bumps, pinkish and redish, like chicken pox only bigger, looked like you could pop them, he also had the effects in his mouth, the ulcers etc... pretty obvious what was going on. (
  • With regard to dermatological aspects, lichen planus mucosae, oral leucoplakia, pemphigus vulgaris, and aphthous mouth ulcers should be considered. (
  • These nevi most often occur on the mouth (oral) mucosa (plural: mucosae). (
  • Several types of malignant cancers occur in the mouth and throat. (
  • Cancers of the mouth and throat occur in twice as many men as women. (
  • Release of benzonatate from the capsule in the mouth can produce a temporary local anesthesia of the oral mucosa and choking could occur. (
  • You have mucosa in the nose, mucosa in the mouth, but you also have mucosa in the eye,' he continued. (
  • A blocked nose causes reliance on mouth breathing, which tends to dehydrate the already inflamed throat. (
  • Bacteria and viruses can invade the thin moist skin (mucosa) lining the throat. (
  • Lip cancer is a form of head and neck cancer that starts in the squamous cells of the lips and mouth. (
  • Early signs can include a sore or lump that does not heal on the lips or in the mouth. (
  • Squamous cells are thin, flat cells that line the lips and other areas of the mouth. (
  • The most common symptom of lip cancer is a sore on the lips or inside the mouth that does not heal. (
  • Lips are thin, fairly dry, with the edge to the corners of the mouth with black pigmentation. (
  • Nasal obstruction can lead to mouth breathing, which can lead to dryness of the mouth, lips and throat. (
  • Interestingly, for reasons that I, and I don't think anyone can explain very well, the lips tend to be an extension of the mouth rather than a component of the skin involvement. (
  • Studying how rare immune diseases affect the mouth can reveal general insights about the immune system and lead to better interventions for both rare and common diseases of the mouth and elsewhere in the body. (
  • The discovery of this abnormal immune response could lead to better therapies for fungal infections in patients with APECED and other diseases and adds to our knowledge about the immune mechanisms at play in the mouth and other mucosal tissues. (
  • Perform surgery to prepare the mouth for dental implants and to aid in the regeneration of deficient bone and gum tissues. (
  • A recent study by a team that included NIDCR scientists adds an unexpected twist to what was known about the immune disturbances that allow fungus to take hold in the body's mucosal tissues, such as the mouth. (
  • Because the mouth is easy to access and biologically similar to mucosal tissues throughout the body, it's an obvious site to study mechanisms of disease," says NIDCR immunologist Niki Moutsopoulos, DDS, PhD , who is a senior author on the paper. (
  • A surgical procedure to ease snoring by removing or reshaping some of the tissues in the mouth (usually the uvula and soft palate) that vibrate and cause the noise of snoring. (
  • In addition, tobacco irritates the mouth tissues and respiratory tract, which prevents proper oxygenation with its consequent effect on breath. (
  • Therefore, they can reach the soft tissues of the floor of the mouth, the neck, and the cheeks. (
  • Cyclooxygenase-1 (COX-1) has been proposed to generate prostaglandins that maintain organ function, protect the integrity of the gastric mucosa, and generate platelet-derived thromboxane responsible for platelet aggregation and vasoconstriction. (
  • This is the tissue that lines the mouth. (
  • University of Michigan researchers are testing a new procedure in which they can take a tiny piece of a person's mouth lining, grow it into a dollar-bill sized piece of tissue and graft that expanded piece into the donor's mouth to heal a wound. (
  • Feinberg said tissue engineering has many advantages, including a smaller donor site that heals faster and a graft that is mucosal cells, more like the mouth lining, not skin. (
  • Eventually, Feinberg hopes to see the treatment used not only for small mouth wounds but for major reconstructive surgery where the patient cannot physically donate enough tissue for repairs. (
  • Skin works for covering the wound, but is not as pliable as the mucosal lining of the mouth, and if it is too thick, it might even grow hair inside the mouth. (
  • This special environment helps a tiny piece of mucosal mouth lining grow to the size of a quarter within a few weeks, and a dollar bill within about a month. (
  • Incidence rates of mouth and throat cancers vary widely from country to country. (
  • Other less common cancers of the mouth and throat include tumors of the minor salivary glands called adenocarcinomas and lymphoma . (
  • The remaining 10 per cent is secreted by hundreds of minor salivary glands beneath the oral mucosa. (
  • The FDA has approved Radiesse to treat: Moderate to severe facial wrinkles and folds, such as nasolabial folds (the lines running from your nostrils to your mouth) Marionette lines (lines around your mouth) Crow's feet (lines around the eyes) Brow furrows (lines between your eyebrows) Radiesse is also FDA-approved for use on the hands and other areas of the body. (
  • Dental caries is an infectious disease caused by bacteria in the mouth . (
  • Suitable for sore throats to treat irritative and inflammatory conditions of the mouth and throat that may be caused by external irritants (viruses, bacteria, allergens, smoke, smog, dust). (
  • Mouth Mucosa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (
  • Symptoms include burning in mouth, throat and stomach. (
  • It also helps protect the stomach against excess acid and is used for its soothing effect on the mucosa of the gut. (
  • More than 90% of oral mucosa cancers, including lip cancers, begin in the squamous cells of the epidermis. (
  • Previous work by Moutsopoulos and others focused on immune cells called T-helper 17 cells, which normally protect the mouth from fungal and other infections by producing a signaling molecule called interleukin-17 (IL-17). (
  • The mouth is a common site for graft-versus-host disease (GVHD) following a transplant with donor cells. (
  • The affected mucosa becomes erythema-tous and swollen, making wearing of the denture and eating and drinking difficult. (
  • 1. Petechiae dispersed throughout all or any part of the palatal mucosa in contact with the denture as Newton type I. (
  • 17 , 18 The chronic systemic inflammation and dysbiosis (bacterial imbalances in the mouth) that are characteristic of periodontal disease can exacerbate these conditions. (
  • [2] Changes indicative of disease are seen as alterations in the oral mucosa lining the mouth, which can reveal systemic conditions, such as diabetes or vitamin deficiency , or the local effects of chronic tobacco or alcohol use. (
  • Chronic irritation from foreign materials or objects in the mouth. (
  • What Facts Should I Know About Oral Cancer (Throat and Mouth Cancer)? (
  • Tumors in the mouth (oral cancer ) and throat (oropharyngeal cancer ) include both benign (not cancer) and malignant types. (
  • Cancers of the mouth and throat do not always metastasize , but those that do usually spread first to the lymph nodes of the neck. (
  • What Are Mouth and Throat Cancer Symptoms and Signs ? (
  • But also remember that without all the information such as x-rays etc., the dentist may not be able to give you a complete report of your mouth. (
  • Your mouth is like a wee cave, and to peer into it's furthest recesses, the dentist needs to shine a light. (
  • Your dentist will start at one side of your mouth, say top right, at the back, and count around until they reach the top left at the back. (
  • Asymmetry of the face and mouth also warns a dentist of a health issue. (
  • It can affect all parts of the mouth and should be followed carefully by a dentist familiar with the signs of GVHD. (
  • As a temporary solution for pain relief until you get to the dentist, rinse your mouth with a solution of 1 dl of lukewarm water, 2 teaspoons of vinegar and 1 teaspoon of salt. (
  • When the oral mucosa becomes atrophic from chemotherapy and renewal of oral epithelium has been slowed, local trauma leads to ulceration, with nonkeratinized sites being the most vulnerable. (
  • A dry mouth (xerostomia) from decreased salivary flow (hyposalivation) secondary to chemotherapy reduces natural lubrication and contributes to the ease of trauma-induced ulceration, difficulty in eating and swallowing (dysphagia), and the accumulation of debris in the mouth. (
  • People who have mouth sores that do not heal within 2 weeks or that partially heal and then come back should see a doctor. (
  • Any irritations in the mouth mucosa takes a long time to heal. (
  • [3] The oral mucosa tends to heal faster and with less scar formation compared to the skin. (
  • Many types of people have trouble with mouth wounds that do not heal well on their own---patients going through cancer chemotherapy, for example, or people with diabetes . (
  • Conditions which predispose to atrophy are iron deficiency, tertiary syphilis, oral sub mucosa fibrosis. (
  • The lymph nodes in front and behind the ears, under the floor of the mouth and chin, and the midline of the neck, sides, and back of the neck are palpated to determine if any swelling or tenderness is present. (
  • For example, xerostomia (dry mouth) is a side effect for hundreds of medications. (
  • 12 Radiotherapy to the mouth, head, or neck can cause severe xerostomia due to hyposalivation. (
  • Nyctimystes nullicedens has green pigmentation on the mucosa of its mouth. (
  • Doctors use the endoscope to remove tumors from the mucosa. (
  • Additions of three chemical synergists to this mixture has been shown to allow for absorption through the mouth allowing a high percentage of the active ingredients to bypass digestion. (
  • To detect swelling on the floor of the mouth, the area inside the mouth is felt with the finger of one hand while a finger of the other hand feels below the chin. (
  • Graft-versus-host disease is also thought to contribute to dry mouth symptoms. (
  • Existing treatments include taking a skin graft from a site such as a leg and stitching it into the mouth. (
  • The mouth is a common target of graft-versus-host disease. (
  • so every single patient that has graft-versus-host disease in the mouth doesn't have the same condition. (
  • Inflammation of the mucosa of the mouth. (
  • Patients present with pain and burning sensation in the mouth, erythema, inflammation with swelling of the palatal mucosa. (
  • What are these pimple like bumps in my mouth? (
  • Little, pimple-like white bumps inside your mouth can be triggered by multiple conditions, such as canker sores, mucus cysts, oral lichen planus and swollen papillae. (
  • Inclusion cyst: a harmless round mass in the mucosa of the mouth, much like a pimple in a different location. (
  • At first sight, it looks like a kind of pimple on the oral mucosa or on the skin. (
  • Thus, the purpose of the present study was to evaluate the effect of dexmedetomidine injected into the oral mucosa in combination with lidocaine on local anesthetic potency in humans. (
  • Biology of the Mouth The mouth is the entrance to both the digestive and the respiratory systems. (
  • What kind of lump is on the roof of the mouth? (
  • This is a hard bony protrusion on the palate (roof of the mouth). (
  • In their research, Feinberg and Izumi took thin pieces of mucosa from the roof of the patients' mouths, about as big around as the end of a pencil eraser. (
  • Patients with dry mouth can develop cracks and fissures in the oral mucosa and halitosis can be another unpleasant feature. (
  • Oral mucosa consists of two layers, the surface stratified squamous epithelium and the deeper lamina propria . (
  • This delicate balance of microbes in the mouth and the rest of the digestive tract can be thrown out of whack easily, creating a range of health problems. (
  • Patients may initially describe generalized burning or sensitivity of the oral mucosa about 1 week after starting chemotherapy. (
  • That's generally related to symptoms of mouth sensitivity. (