Molecular Biology: A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.Biology: One of the BIOLOGICAL SCIENCE DISCIPLINES concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals, plants, and microorganisms.Systems Biology: Comprehensive, methodical analysis of complex biological systems by monitoring responses to perturbations of biological processes. Large scale, computerized collection and analysis of the data are used to develop and test models of biological systems.Developmental Biology: The field of biology which deals with the process of the growth and differentiation of an organism.Computational Biology: A field of biology concerned with the development of techniques for the collection and manipulation of biological data, and the use of such data to make biological discoveries or predictions. This field encompasses all computational methods and theories for solving biological problems including manipulation of models and datasets.Synthetic Biology: A field of biological research combining engineering in the formulation, design, and building (synthesis) of novel biological structures, functions, and systems.History, 20th Century: Time period from 1901 through 2000 of the common era.Nobel PrizeHistory, 21st Century: Time period from 2001 through 2100 of the common era.Software: Sequential operating programs and data which instruct the functioning of a digital computer.Genomics: The systematic study of the complete DNA sequences (GENOME) of organisms.Models, Biological: Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.Internet: A loose confederation of computer communication networks around the world. The networks that make up the Internet are connected through several backbone networks. The Internet grew out of the US Government ARPAnet project and was designed to facilitate information exchange.Biotechnology: Body of knowledge related to the use of organisms, cells or cell-derived constituents for the purpose of developing products which are technically, scientifically and clinically useful. Alteration of biologic function at the molecular level (i.e., GENETIC ENGINEERING) is a central focus; laboratory methods used include TRANSFECTION and CLONING technologies, sequence and structure analysis algorithms, computer databases, and gene and protein structure function analysis and prediction.Molecular Sequence Data: Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.Algorithms: A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.Directories as Topic: Lists of persons or organizations, systematically arranged, usually in alphabetic or classed order, giving address, affiliations, etc., for individuals, and giving address, officers, functions, and similar data for organizations. (ALA Glossary of Library and Information Science, 1983)Gene Expression Profiling: The determination of the pattern of genes expressed at the level of GENETIC TRANSCRIPTION, under specific circumstances or in a specific cell.Databases, Genetic: Databases devoted to knowledge about specific genes and gene products.Databases, Factual: Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.Research: Critical and exhaustive investigation or experimentation, having for its aim the discovery of new facts and their correct interpretation, the revision of accepted conclusions, theories, or laws in the light of newly discovered facts, or the practical application of such new or revised conclusions, theories, or laws. (Webster, 3d ed)Signal Transduction: The intracellular transfer of information (biological activation/inhibition) through a signal pathway. In each signal transduction system, an activation/inhibition signal from a biologically active molecule (hormone, neurotransmitter) is mediated via the coupling of a receptor/enzyme to a second messenger system or to an ion channel. Signal transduction plays an important role in activating cellular functions, cell differentiation, and cell proliferation. Examples of signal transduction systems are the GAMMA-AMINOBUTYRIC ACID-postsynaptic receptor-calcium ion channel system, the receptor-mediated T-cell activation pathway, and the receptor-mediated activation of phospholipases. Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. Some signal transduction pathways may be part of larger signal transduction pathways; for example, protein kinase activation is part of the platelet activation signal pathway.Sequence Analysis, DNA: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.Human Genome Project: A coordinated effort of researchers to map (CHROMOSOME MAPPING) and sequence (SEQUENCE ANALYSIS, DNA) the human GENOME.Base Sequence: The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.History, 19th Century: Time period from 1801 through 1900 of the common era.Biochemistry: The study of the composition, chemical structures, and chemical reactions of living things.Information Storage and Retrieval: Organized activities related to the storage, location, search, and retrieval of information.Genetics: The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.Biological Evolution: The process of cumulative change over successive generations through which organisms acquire their distinguishing morphological and physiological characteristics.Proteins: Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.Amino Acid Sequence: The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.Polymerase Chain Reaction: In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships.User-Computer Interface: The portion of an interactive computer program that issues messages to and receives commands from a user.Phylogeny: The relationships of groups of organisms as reflected by their genetic makeup.Cell Physiological Phenomena: Cellular processes, properties, and characteristics.Genetic Techniques: Chromosomal, biochemical, intracellular, and other methods used in the study of genetics.Forensic Sciences: Disciplines that apply sciences to law. Forensic sciences include a wide range of disciplines, such as FORENSIC TOXICOLOGY; FORENSIC ANTHROPOLOGY; FORENSIC MEDICINE; FORENSIC DENTISTRY; and others.Computer Simulation: Computer-based representation of physical systems and phenomena such as chemical processes.Database Management Systems: Software designed to store, manipulate, manage, and control data for specific uses.Societies, Scientific: Societies whose membership is limited to scientists.Genome: The genetic complement of an organism, including all of its GENES, as represented in its DNA, or in some cases, its RNA.Genetic Engineering: Directed modification of the gene complement of a living organism by such techniques as altering the DNA, substituting genetic material by means of a virus, transplanting whole nuclei, transplanting cell hybrids, etc.Oligonucleotide Array Sequence Analysis: Hybridization of a nucleic acid sample to a very large set of OLIGONUCLEOTIDE PROBES, which have been attached individually in columns and rows to a solid support, to determine a BASE SEQUENCE, or to detect variations in a gene sequence, GENE EXPRESSION, or for GENE MAPPING.DNA: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).Mutation: Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.Proteomics: The systematic study of the complete complement of proteins (PROTEOME) of organisms.Gene Expression Regulation: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.Sequence Alignment: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.Programming Languages: Specific languages used to prepare computer programs.Gene Regulatory Networks: Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations.Phenotype: The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment.Models, Molecular: Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.Models, Genetic: Theoretical representations that simulate the behavior or activity of genetic processes or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Science: The study of natural phenomena by observation, measurement, and experimentation.Terminology as Topic: The terms, expressions, designations, or symbols used in a particular science, discipline, or specialized subject area.Evolution, Molecular: The process of cumulative change at the level of DNA; RNA; and PROTEINS, over successive generations.Biochemical Phenomena: The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.Computer Graphics: The process of pictorial communication, between human and computers, in which the computer input and output have the form of charts, drawings, or other appropriate pictorial representation.Databases, Nucleic Acid: Databases containing information about NUCLEIC ACIDS such as BASE SEQUENCE; SNPS; NUCLEIC ACID CONFORMATION; and other properties. Information about the DNA fragments kept in a GENE LIBRARY or GENOMIC LIBRARY is often maintained in DNA databases.Metabolic Networks and Pathways: Complex sets of enzymatic reactions connected to each other via their product and substrate metabolites.Molecular Targeted Therapy: Treatments with drugs which interact with or block synthesis of specific cellular components characteristic of the individual's disease in order to stop or interrupt the specific biochemical dysfunction involved in progression of the disease.Laboratories: Facilities equipped to carry out investigative procedures.Plants: Multicellular, eukaryotic life forms of kingdom Plantae (sensu lato), comprising the VIRIDIPLANTAE; RHODOPHYTA; and GLAUCOPHYTA; all of which acquired chloroplasts by direct endosymbiosis of CYANOBACTERIA. They are characterized by a mainly photosynthetic mode of nutrition; essentially unlimited growth at localized regions of cell divisions (MERISTEMS); cellulose within cells providing rigidity; the absence of organs of locomotion; absence of nervous and sensory systems; and an alternation of haploid and diploid generations.Gene Expression: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.Databases, Protein: Databases containing information about PROTEINS such as AMINO ACID SEQUENCE; PROTEIN CONFORMATION; and other properties.Cells: The fundamental, structural, and functional units or subunits of living organisms. They are composed of CYTOPLASM containing various ORGANELLES and a CELL MEMBRANE boundary.Technology: The application of scientific knowledge to practical purposes in any field. It includes methods, techniques, and instrumentation.Cloning, Molecular: The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.Physiology: The biological science concerned with the life-supporting properties, functions, and processes of living organisms or their parts.Allergy and Immunology: A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.RNA: A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)Individualized Medicine: Therapeutic approach tailoring therapy for genetically defined subgroups of patients.Microbiology: The study of microorganisms such as fungi, bacteria, algae, archaea, and viruses.RNA, Messenger: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.History, 18th Century: Time period from 1701 through 1800 of the common era.Biomedical Research: Research that involves the application of the natural sciences, especially biology and physiology, to medicine.Patents as Topic: Exclusive legal rights or privileges applied to inventions, plants, etc.Enzymes: Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.Teaching: The educational process of instructing.Proteome: The protein complement of an organism coded for by its genome.Cybernetics: That branch of learning which brings together theories and studies on communication and control in living organisms and machines.Cell Biology: The study of the structure, behavior, growth, reproduction, and pathology of cells; and the function and chemistry of cellular components.Students: Individuals enrolled in a school or formal educational program.Transcription, Genetic: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.Transcriptome: The pattern of GENE EXPRESSION at the level of genetic transcription in a specific organism or under specific circumstances in specific cells.Drug Design: The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.Sequence Analysis: A multistage process that includes the determination of a sequence (protein, carbohydrate, etc.), its fragmentation and analysis, and the interpretation of the resulting sequence information.Bacteria: One of the three domains of life (the others being Eukarya and ARCHAEA), also called Eubacteria. They are unicellular prokaryotic microorganisms which generally possess rigid cell walls, multiply by cell division, and exhibit three principal forms: round or coccal, rodlike or bacillary, and spiral or spirochetal. Bacteria can be classified by their response to OXYGEN: aerobic, anaerobic, or facultatively anaerobic; by the mode by which they obtain their energy: chemotrophy (via chemical reaction) or PHOTOTROPHY (via light reaction); for chemotrophs by their source of chemical energy: CHEMOLITHOTROPHY (from inorganic compounds) or chemoorganotrophy (from organic compounds); and by their source for CARBON; NITROGEN; etc.; HETEROTROPHY (from organic sources) or AUTOTROPHY (from CARBON DIOXIDE). They can also be classified by whether or not they stain (based on the structure of their CELL WALLS) with CRYSTAL VIOLET dye: gram-negative or gram-positive.Transcription Factors: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.Genetic Variation: Genotypic differences observed among individuals in a population.Reproduction: The total process by which organisms produce offspring. (Stedman, 25th ed)Sequence Analysis, Protein: A process that includes the determination of AMINO ACID SEQUENCE of a protein (or peptide, oligopeptide or peptide fragment) and the information analysis of the sequence.Translational Medical Research: The application of discoveries generated by laboratory research and preclinical studies to the development of clinical trials and studies in humans. A second area of translational research concerns enhancing the adoption of best practices.DNA, Complementary: Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.Clinical Trials as Topic: Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.Protein Interaction Mapping: Methods for determining interaction between PROTEINS.Genome, Viral: The complete genetic complement contained in a DNA or RNA molecule in a virus.Periodicals as Topic: A publication issued at stated, more or less regular, intervals.Curriculum: A course of study offered by an educational institution.Natural Language Processing: Computer processing of a language with rules that reflect and describe current usage rather than prescribed usage.Artificial Intelligence: Theory and development of COMPUTER SYSTEMS which perform tasks that normally require human intelligence. Such tasks may include speech recognition, LEARNING; VISUAL PERCEPTION; MATHEMATICAL COMPUTING; reasoning, PROBLEM SOLVING, DECISION-MAKING, and translation of language.Cell Differentiation: Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.Neurosciences: The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.Universities: Educational institutions providing facilities for teaching and research and authorized to grant academic degrees.Protein Engineering: Procedures by which protein structure and function are changed or created in vitro by altering existing or synthesizing new structural genes that direct the synthesis of proteins with sought-after properties. Such procedures may include the design of MOLECULAR MODELS of proteins using COMPUTER GRAPHICS or other molecular modeling techniques; site-specific mutagenesis (MUTAGENESIS, SITE-SPECIFIC) of existing genes; and DIRECTED MOLECULAR EVOLUTION techniques to create new genes.Data Mining: Use of sophisticated analysis tools to sort through, organize, examine, and combine large sets of information.Species Specificity: The restriction of a characteristic behavior, anatomical structure or physical system, such as immune response; metabolic response, or gene or gene variant to the members of one species. It refers to that property which differentiates one species from another but it is also used for phylogenetic levels higher or lower than the species.Disease Models, Animal: Naturally occurring or experimentally induced animal diseases with pathological processes sufficiently similar to those of human diseases. They are used as study models for human diseases.Luciferases, Bacterial: Luciferases from BACTERIA such as PHOTOBACTERIUM; VIBRIO; and PHOTORHABDUS.Nucleic Acids: High molecular weight polymers containing a mixture of purine and pyrimidine nucleotides chained together by ribose or deoxyribose linkages.Expressed Sequence Tags: Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.Molecular Probe Techniques: The use of devices which use detector molecules to detect, investigate, or analyze other molecules, macromolecules, molecular aggregates, or organisms.Systems Integration: The procedures involved in combining separately developed modules, components, or subsystems so that they work together as a complete system. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)Reproducibility of Results: The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results.Software Design: Specifications and instructions applied to the software.Chromosome Mapping: Any method used for determining the location of and relative distances between genes on a chromosome.Cluster Analysis: A set of statistical methods used to group variables or observations into strongly inter-related subgroups. In epidemiology, it may be used to analyze a closely grouped series of events or cases of disease or other health-related phenomenon with well-defined distribution patterns in relation to time or place or both.Microscopy: The use of instrumentation and techniques for visualizing material and details that cannot be seen by the unaided eye. It is usually done by enlarging images, transmitted by light or electron beams, with optical or magnetic lenses that magnify the entire image field. With scanning microscopy, images are generated by collecting output from the specimen in a point-by-point fashion, on a magnified scale, as it is scanned by a narrow beam of light or electrons, a laser, a conductive probe, or a topographical probe.Models, Animal: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.Molecular Sequence Annotation: The addition of descriptive information about the function or structure of a molecular sequence to its MOLECULAR SEQUENCE DATA record.Epigenesis, Genetic: A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.Reverse Transcriptase Polymerase Chain Reaction: A variation of the PCR technique in which cDNA is made from RNA via reverse transcription. The resultant cDNA is then amplified using standard PCR protocols.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Mammals: Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.MicroRNAs: Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.Antineoplastic Agents: Substances that inhibit or prevent the proliferation of NEOPLASMS.Molecular Imaging: The use of molecularly targeted imaging probes to localize and/or monitor biochemical and cellular processes via various imaging modalities that include RADIONUCLIDE IMAGING; ULTRASONOGRAPHY; MAGNETIC RESONANCE IMAGING; FLUORESCENCE IMAGING; and MICROSCOPY.Educational Measurement: The assessing of academic or educational achievement. It includes all aspects of testing and test construction.DNA Primers: Short sequences (generally about 10 base pairs) of DNA that are complementary to sequences of messenger RNA and allow reverse transcriptases to start copying the adjacent sequences of mRNA. Primers are used extensively in genetic and molecular biology techniques.Stem Cells: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.Information Systems: Integrated set of files, procedures, and equipment for the storage, manipulation, and retrieval of information.Metabolomics: The systematic identification and quantitation of all the metabolic products of a cell, tissue, organ, or organism under varying conditions. The METABOLOME of a cell or organism is a dynamic collection of metabolites which represent its net response to current conditions.Genetic Markers: A phenotypically recognizable genetic trait which can be used to identify a genetic locus, a linkage group, or a recombination event.Genetic Vectors: DNA molecules capable of autonomous replication within a host cell and into which other DNA sequences can be inserted and thus amplified. Many are derived from PLASMIDS; BACTERIOPHAGES; or VIRUSES. They are used for transporting foreign genes into recipient cells. Genetic vectors possess a functional replicator site and contain GENETIC MARKERS to facilitate their selective recognition.Physics: The study of those aspects of energy and matter in terms of elementary principles and laws. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)Gene Library: A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.Online Systems: Systems where the input data enter the computer directly from the point of origin (usually a terminal or workstation) and/or in which output data are transmitted directly to that terminal point of origin. (Sippl, Computer Dictionary, 4th ed)Toxicology: The science concerned with the detection, chemical composition, and biological action of toxic substances or poisons and the treatment and prevention of toxic manifestations.Genetic Therapy: Techniques and strategies which include the use of coding sequences and other conventional or radical means to transform or modify cells for the purpose of treating or reversing disease conditions.Protein Binding: The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.Escherichia coli: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.Forecasting: The prediction or projection of the nature of future problems or existing conditions based upon the extrapolation or interpretation of existing scientific data or by the application of scientific methodology.Sequence Analysis, RNA: A multistage process that includes cloning, physical mapping, subcloning, sequencing, and information analysis of an RNA SEQUENCE.Protein Conformation: The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).Oncogenes: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.Protein Structure, Tertiary: The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.Genotype: The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS.Genome, Human: The complete genetic complement contained in the DNA of a set of CHROMOSOMES in a HUMAN. The length of the human genome is about 3 billion base pairs.Learning: Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.Bacterial Physiological Phenomena: Physiological processes and properties of BACTERIA.Ictaluridae: A family of North American freshwater CATFISHES. It consists of four genera (Ameiurus, Ictalurus, Noturus, Pylodictis,) comprising several species, two of which are eyeless.Immunohistochemistry: Histochemical localization of immunoreactive substances using labeled antibodies as reagents.Congresses as Topic: Conferences, conventions or formal meetings usually attended by delegates representing a special field of interest.Metabolism: The chemical reactions that occur within the cells, tissues, or an organism. These processes include both the biosynthesis (ANABOLISM) and the breakdown (CATABOLISM) of organic materials utilized by the living organism.Models, Theoretical: Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.Plasmids: Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS.Nanotechnology: The development and use of techniques to study physical phenomena and construct structures in the nanoscale size range or smaller.Host-Pathogen Interactions: The interactions between a host and a pathogen, usually resulting in disease.Cell Line: Established cell cultures that have the potential to propagate indefinitely.Tumor Markers, Biological: Molecular products metabolized and secreted by neoplastic tissue and characterized biochemically in cells or body fluids. They are indicators of tumor stage and grade as well as useful for monitoring responses to treatment and predicting recurrence. Many chemical groups are represented including hormones, antigens, amino and nucleic acids, enzymes, polyamines, and specific cell membrane proteins and lipids.Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)Microfluidic Analytical Techniques: Methods utilizing the principles of MICROFLUIDICS for sample handling, reagent mixing, and separation and detection of specific components in fluids.Gene Expression Regulation, Neoplastic: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.Yeasts: A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED.Information Theory: An interdisciplinary study dealing with the transmission of messages or signals, or the communication of information. Information theory does not directly deal with meaning or content, but with physical representations that have meaning or content. It overlaps considerably with communication theory and CYBERNETICS.Databases as Topic: Organized collections of computer records, standardized in format and content, that are stored in any of a variety of computer-readable modes. They are the basic sets of data from which computer-readable files are created. (from ALA Glossary of Library and Information Science, 1983)Nucleic Acid Hybridization: Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)Gene Expression Regulation, Developmental: Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action during the developmental stages of an organism.High-Throughput Nucleotide Sequencing: Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.Virology: The study of the structure, growth, function, genetics, and reproduction of viruses, and VIRUS DISEASES.Virus Replication: The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.Caenorhabditis elegans: A species of nematode that is widely used in biological, biochemical, and genetic studies.Genome, Fungal: The complete gene complement contained in a set of chromosomes in a fungus.Flowers: The reproductive organs of plants.Bacterial Proteins: Proteins found in any species of bacterium.Prognosis: A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.Viral Proteins: Proteins found in any species of virus.DNA, Bacterial: Deoxyribonucleic acid that makes up the genetic material of bacteria.Vocabulary, Controlled: A specified list of terms with a fixed and unalterable meaning, and from which a selection is made when CATALOGING; ABSTRACTING AND INDEXING; or searching BOOKS; JOURNALS AS TOPIC; and other documents. The control is intended to avoid the scattering of related subjects under different headings (SUBJECT HEADINGS). The list may be altered or extended only by the publisher or issuing agency. (From Harrod's Librarians' Glossary, 7th ed, p163)Pharmacogenetics: A branch of genetics which deals with the genetic variability in individual responses to drugs and drug metabolism (BIOTRANSFORMATION).Saccharomyces cerevisiae: A species of the genus SACCHAROMYCES, family Saccharomycetaceae, order Saccharomycetales, known as "baker's" or "brewer's" yeast. The dried form is used as a dietary supplement.RNA Interference: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.Genetic Diseases, Inborn: Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero.Binding Sites: The parts of a macromolecule that directly participate in its specific combination with another molecule.Structure-Activity Relationship: The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.Green Fluorescent Proteins: Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.Models, Chemical: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.Clinical Laboratory Techniques: Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.Recombination, Genetic: Production of new arrangements of DNA by various mechanisms such as assortment and segregation, CROSSING OVER; GENE CONVERSION; GENETIC TRANSFORMATION; GENETIC CONJUGATION; GENETIC TRANSDUCTION; or mixed infection of viruses.Cell Proliferation: All of the processes involved in increasing CELL NUMBER including CELL DIVISION.Databases, Bibliographic: Extensive collections, reputedly complete, of references and citations to books, articles, publications, etc., generally on a single subject or specialized subject area. Databases can operate through automated files, libraries, or computer disks. The concept should be differentiated from DATABASES, FACTUAL which is used for collections of data and facts apart from bibliographic references to them.Animals, Genetically Modified: ANIMALS whose GENOME has been altered by GENETIC ENGINEERING, or their offspring.Regeneration: The physiological renewal, repair, or replacement of tissue.Pattern Recognition, Automated: In INFORMATION RETRIEVAL, machine-sensing or identification of visible patterns (shapes, forms, and configurations). (Harrod's Librarians' Glossary, 7th ed)Sequence Tagged Sites: Short tracts of DNA sequence that are used as landmarks in GENOME mapping. In most instances, 200 to 500 base pairs of sequence define a Sequence Tagged Site (STS) that is operationally unique in the human genome (i.e., can be specifically detected by the polymerase chain reaction in the presence of all other genomic sequences). The overwhelming advantage of STSs over mapping landmarks defined in other ways is that the means of testing for the presence of a particular STS can be completely described as information in a database.Genetic Predisposition to Disease: A latent susceptibility to disease at the genetic level, which may be activated under certain conditions.Models, Statistical: Statistical formulations or analyses which, when applied to data and found to fit the data, are then used to verify the assumptions and parameters used in the analysis. Examples of statistical models are the linear model, binomial model, polynomial model, two-parameter model, etc.Bioengineering: The application of engineering principles and methods to living organisms or biological systems.
Molecular biology. Autophagy is executed by autophagy-related (Atg) genes. The first autophagy genes were identified by ... Youle, R; Narendra, D (2011). "Mechanisms of mitophagy". Nature Reviews Molecular Cell Biology. 12: 9-14. doi:10.1038/nrm3028. ... "Autophagy in Health and Disease (Z3), 2007, Keystone Symposia on Molecular and Cellular Biology".. ... "The Journal of Cell Biology. 35 (2): C11-6. doi:10.1083/jcb.35.2.c11. PMC 2107130 . PMID 6055998.. ...
"Nature Reviews Molecular Cell Biology. 14: 759-774. doi:10.1038/nrm3696.. *^ Russell, Ryan C.; Yuan, Hai-Xin; Guan, Kun-Liang ( ... "Molecular Biology of the Cell. 25 (2): 290-301. doi:10.1091/mbc.E13-08-0448. PMC 3890349. PMID 24258026.. ... "Molecular Biology of the Cell. 19 (12): 5360-72. doi:10.1091/mbc.E08-01-0080. PMC 2592660. PMID 18843052.. ... "Molecular Biology of the Cell. 15 (3): 1101-11. doi:10.1091/mbc.E03-09-0704. PMC 363084. PMID 14699058.. ...
Heidelberg: European Molecular Biology Organization.. *^ a b c d Rich, A.; Stevens, C. F. (2004). "Obituary: Francis Crick ( ... Molecular Biology After World War II, published by Cambridge University Press in 2002. His major contribution to molecular ... Molecular biology. In 1954, at the age of 37, Crick completed his Ph.D. thesis: "X-Ray Diffraction: Polypeptides and ... Dickerson, Richard E.; Present at the Flood: How Structural Molecular Biology Came About, Sinauer, 2005; ISBN 0-87893-168-6. ...
C-C chemokine receptor type 6
Molecular biology. The gene is located on the long arm of Chromosome 6 (6q27) on the Watson (plus) strand. It is 139,737 ... Molecular function. • G-protein coupled receptor activity. • signal transducer activity. • chemokine receptor activity. • ... 1996). "Molecular cloning and RNA expression of two new human chemokine receptor-like genes". Biochem. Biophys. Res. Commun. ... Zaballos A, Varona R, Gutiérrez J, Lind P, Márquez G (October 1996). "Molecular cloning and RNA expression of two new human ...
Molecular biology. Domain structure of human tropoelastin. In mammals, the genome only contains one gene for tropoelastin ... Molecular function. • extracellular matrix structural constituent. • protein binding. Cellular component. • proteinaceous ... Sage EH, Gray WR (1977). "Evolution of elastin structure". Advances in Experimental Medicine and Biology. 79: 291-312. doi: ... Muiznieks LD, Weiss AS, Keeley FW (Apr 2010). "Structural disorder and dynamics of elastin". Biochemistry and Cell Biology. 88 ...
Molecular biology. Neomycin resistance is conferred by either one of two aminoglycoside phosphotransferase genes. A ... Oxford Dictionary of Biochemistry and Molecular Biology (2nd ed.). Oxford University Press. p. 453.. ... neo gene is commonly included in DNA plasmids used by molecular biologists to establish stable mammalian cell lines expressing ... Nature Chemical Biology. 7 (11): 843-52. doi:10.1038/nchembio.671. PMID 21983602.. ...
... s in molecular biology. Peptides received prominence in molecular biology for several reasons. The first is that ... Methods in Molecular Biology. Methods in Molecular Biology™. 310: 227-40. doi:10.1007/978-1-59259-948-6_16. ISBN 978-1-58829- ... Bulinski JC (1986). "Peptide antibodies: new tools for cell biology". International Review of Cytology. International Review of ...
Hepatitis C virus
4 Molecular biology. *5 Replication. *6 Genotypes *6.1 Clinical importance. *6.2 Recombination ... De Francesco R (1999). "Molecular virology of the hepatitis C virus". J Hepatol. 31 (Suppl 1): 47-53. doi:10.1016/S0168-8278(99 ... Medical Molecular Morphology. 39 (2): 63-71. doi:10.1007/s00795-006-0317-8. ISSN 1860-1480. PMID 16821143. S2CID 24668769.. ... "Phylogeography and molecular epidemiology of hepatitis C virus genotype 2 in Africa". J. Gen. Virol. 90 (Pt 9): 2086-96. doi ...
Molecular Biology After World War II", published by CUP in 2002. His major contribution to molecular biology in Cambridge is ... Heidelberg: European Molecular Biology Organization.. *^ a b c d Rich, A.; Stevens, C. F. (2004). "Obituary: Francis Crick ( ... Dickerson, Richard E.; "Present at the Flood: How Structural Molecular Biology Came About", Sinauer, 2005; ISBN 0-87893-168-6. ... Soraya De Chadarevian; Designs For Life: Molecular Biology After World War II, CUP 2002, 444 pp; ISBN 0-521-57078-6. ...
The addition of molecular genetics has led to evolutionary developmental biology, which explains evolution at the molecular ... Cell and molecular biology. In 1881, the embryologist Wilhelm Roux published Der Kampf der Theile im Organismus (The ... The environment of a genome includes the molecular biology in the cell, other cells, other individuals, populations, species, ... Reviews in Cell Biology and Molecular Medicine. 2 (3): 60-93.. *^ McKusick, Victor A.; Gross, Matthew B. (18 November 2014). " ...
Molecular biology. Introduction. Leukocyte extravasation. The phases of the leukocyte extravasation depicted in the ... "Journal of Leukocyte Biology. 100 (5): 1027-1035. doi:10.1189/jlb.3MA0216-087R. PMC 5069089. PMID 27190303.. ... "The Journal of Cell Biology. 166 (6): 913-23. doi:10.1083/jcb.200403144. PMC 2172126. PMID 15364963.. ... "The Journal of Cell Biology. 166 (6): 913-23. doi:10.1083/jcb.200403144. PMC 2172126. PMID 15364963.. ...
Melo, J. V. (1996). "The molecular biology of chronic myeloid leukaemia". Leukemia. 10 (5): 751-756. PMID 8656667.. ... Depending on the precise location of fusion, the molecular weight of this protein can range from 185 to 210 kDa. Consequently, ... From basic mechanisms to molecular therapeutics". Annals of Internal Medicine. 138 (10): 819-830. doi:10.7326/0003-4819-138-10- ...
Crimean-Congo hemorrhagic fever
Molecular biology. The genome is circular, negative sense RNA in three parts - Small (S), Medium (M) and Large (L). The L ... "Molecular detection of Crimean-Congo haemorrhagic fever (CCHF) virus in ticks from southeastern Iran". Ticks and Tick-borne ... "Molecular Epidemiology of Crimean-Congo Hemorrhagic Fever Virus in Kosovo". PLoS Negl Trop Dis. 8 (1): e2647. doi:10.1371/ ...
Significance for plant molecular biology. In the model plant Arabidopsis thaliana, trichome formation is initiated by the ... Hülskamp, Martin (June 2004). "Plant Trichomes: A Model for Cell Differentiation". Molecular Cell Biology. 5: 471-480 - via ... Levin, Donald A. (1973). "The Role of Trichomes in Plant Defense". The Quarterly Review of Biology. 48 (1): 3-15. doi:10.1086/ ... The International Journal of Developmental Biology. 49 (5-6): 579-584. doi:10.1387/ijdb.051983ss. ISSN 0214-6282. PMID 16096966 ...
Sense (molecular biology)
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the ... The concept has also been exploited as a molecular biology technique, by artificially introducing a transgene coding for ... To help molecular biologists specifically identify each strand individually, the two strands are usually differentiated as the ... Retrieved from "https://en.wikipedia.org/w/index.php?title=Sense_(molecular_biology)&oldid=965305131" ...
Portal:Molecular and cellular biology
Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between ... Research in cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and developmental biology ... Stubs: Molecular and cellular biology stubs; Biochemistry stubs; Cell biology stubs; Developmental biology stubs; Genetics ... Molecular and cellular biology news. *October 2009, Nobel foundation: The Nobel Prize in Physiology or Medicine 2009 went to ...
Molecular biology. In addition to microarrays, biochips have been designed for two-dimensional electrophoresis, ... Methods in Molecular Biology. Humana Press, New York, NY. pp. 43-52. doi:10.1007/978-1-4939-2353-3_4. ISBN 9781493923526.. ... Advances in microfluidics technology are revolutionizing molecular biology procedures for enzymatic analysis (e.g., glucose and ... "Integrative Biology. 2: 604-629. doi:10.1039/C0IB00049C.. *^ Seymour, J.R.; Simo', R.; Ahmed, T.; Stocker, R. (2010). " ...
Molecular biology research and viral therapy. Bacteriophages, the viruses which infect bacteria, can be relatively easily ... Certain genetic elements derived from viruses, such as highly effective promoters, are commonly used in molecular biology ... horizontal gene transfer is one reason why they served as a major research tool in the early development of molecular biology. ... Cann, Alan (2011). Principles of Molecular Virology (5 ed.). London: Academic Press. ISBN 978-0123849397.. ...
Molecular biology. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes ... "The Journal of Cell Biology. 81 (3): 570-80. doi:10.1083/jcb.81.3.570. PMC 2110384 . PMID 379021.. ... Cell biology. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the ... "The Journal of Cell Biology. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMC 2064177 . PMID 16831889.. ...
Biology. Molecular biology. L-lactic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 1 ( ... Article in "Mammalian Biology" *^ a b McArdle WD, Katch FI, Katch VL (2010). Exercise Physiology: Energy, Nutrition, and Human ... König H, Fröhlich J (2009). Lactic acid bacteria in Biology of Microorganisms on Grapes, in Must and in Wine. Springer-Verlag. ... It has a molecular formula CH3CH(OH)CO2H. It is white in solid state and it is extremely soluble in water. Solubility is so ...
Complementarity (molecular biology)
Molecular biology of the gene (Seventh edition. ed.). Boston: Benjamin-Cummings Publishing Company. ISBN 978-0-32176243-6.. .mw ... In molecular biology, complementarity describes a relationship between two structures each following the lock-and-key principle ... This article is related to Molecular Biology. For other uses see complementarity. ... Journal of Molecular Biology. 269 (1): 52-66. doi:10.1006/jmbi.1997.1021. PMID 9193000.. ...
Hereditary neuropathy with liability to pressure palsy
Gelatin silver process
The addition of molecular genetics has led to evolutionary developmental biology, which explains evolution at the molecular ... Cell and molecular biology. In 1881, the embryologist Wilhelm Roux published Der Kampf der Theile im Organismus (The ... The environment of a genome includes the molecular biology in the cell, other cells, other individuals, populations, species, ... Reviews in Cell Biology and Molecular Medicine. 2 (3): 60-93.. CS1 maint: Multiple names: authors list (link). ...
Molecular biology. In molecular biology, the presence of amylase can serve as an additional method of selecting for ... "History of Biology: Cuvier, Schwann and Schleiden". pasteur.fr. 8 April 2002. Archived from the original on 24 September 2015. ... Maton A, Hopkins J, McLaughlin CW, Johnson S, Warner MQ, LaHart D, Wright JD (1993). Human Biology and Health. Englewood Cliffs ... Molecular BioSystems. 7 (3): 718-730. doi:10.1039/c0mb00204f. PMID 21085740. S2CID 45819617.. ...
Anaplastic large-cell lymphoma
In 1970, Villa-Komaroff enrolled at the Massachusetts Institute of Technology (MIT) for graduate work in molecular biology. Her ... There, she continued to establish her name in molecular biology, and in 1995 a television documentary called "DNA Detective" ... Villa-Komaroff used the then-new molecular biology technology of recombinant DNA to address a number of fundamental questions ... Member of Biology Directorate for the National Science Foundation. *Member of the Institute of Medicine Committee on Assessing ...
"Molecular Biology. 53 (5): 704-717. doi:10.1134/S0026893319050108. PMID 31661479. S2CID 204758015.. ... Immune cells not only recognise pathogen-associated molecular patterns but also damage-associated molecular patterns from ... "Experimental & Molecular Medicine. 45 (12): e66. doi:10.1038/emm.2013.97. PMC 3880462. PMID 24310172.. ... eds.). Sepsis and Non-infectious Systemic Inflammation: From Biology to Critical Care. John Wiley & Sons. p. 3. ISBN ...
American Society for Biochemistry and Molecular Biology
Join a community of molecular life scientists. The American Society for Biochemistry and Molecular Biology helps you excel at ... American society for biochemistry and molecular biology. Join Renew About Us Search Sign In ... Ive always been fascinated by molecular mechanisms of biological processes, and this is the best place to learn more about ... The ASBMB is a leader in professional development for molecular life scientists at every step of their career journeys. ...
Protein and pharmaceutical engineering: proceedings of a UCLA Symposium held ... - Upjohn Company, University of California,...
Molecular biology - Wikipedia
... arising from molecular biology are covered under gene therapy whereas the use of molecular biology or molecular cell biology in ... Molecular biology /məˈlɛkjʊlər/ is the branch of biology that concerns the molecular basis of biological activity in and ... Main article: History of molecular biology. While molecular biology was established as an official branch of science in the ... Molecular biology is the study of the molecular underpinnings of the processes of replication, transcription, translation, and ...
Wiley: Molecular Biology
Biology Core Molecular Lab
Molecular Biology Reports - Springer
Molecular Biology Reports. An International Journal on Molecular and Cellular Biology ISSN: 0301-4851 (Print) 1573-4978 (Online ... Molecular Biology Reports publishes original research papers and review articles that demonstrate novel molecular and cellular ... Molecular Biology Reports. Coverage. Volume 1 / 1974 - Volume 45 / 2018. Print ISSN. 0301-4851. Online ISSN. 1573-4978. ... All aspects of Molecular and Cellular Biology. All aspects related to the different structures and functions of the cell ( ...
Plant Molecular Biology | Home
Plant Molecular Biology is an international journal dedicated to rapid publication of original research in all areas of plant ... Plant Molecular Biology is an international journal dedicated to rapid publication of original research in all areas of plant ... An international journal dedicated to rapid publication of original research in all areas of plant biology ... Coverage includes research in comparative genomics, functional genomics, proteomics, bioinformatics, computational biology, ...
Portal:Molecular and cellular biology - Wikipedia
Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between ... Research in cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and developmental biology ... Stubs: Molecular and cellular biology stubs; Biochemistry stubs; Cell biology stubs; Developmental biology stubs; Genetics ... Molecular and cellular biology news. *October 2009, Nobel foundation: The Nobel Prize in Physiology or Medicine 2009 went to ...
Newborn Screening and Molecular Biology Branch | CDC
Newborn Screening and Molecular Biology Branchplus icon *Severe Combined Immunodeficiency (SCID) ... The Newborn Screening and Molecular Biology Branch (NSMBB) has the only laboratory in the world devoted to ensuring the ... The initiative is an ongoing collaboration between the CDC Foundation and the Newborn Screening and Molecular Biology Branch. ... CDCs Newborn Screening and Molecular Biology Branch (NSMBB) has been granted ISO/IEC 17043 accreditation by the American ...
Postdoctoral Position in Molecular Biology / Signal Transduction /
... Cancer / Inflammation, with University of Liège (ULg). Apply ... The Unit of Molecular Biology of Diseases is seeking a talented and highly motivated post-doctoral candidate in order to ... Postdoctoral Position in Molecular Biology / Signal Transduction / Cancer / Inflammation. University of Liège (ULg). Liège, ... Molecular Cell 2004).. Profile. Applicants are recently qualified PhD students or postdoc scientists with no more. than 5 years ...
Computational Molecular Biology | The MIT Press
Recent research in molecular biology has produced a remarkably detailed understanding of how living things operate. Becoming ... Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often ... conversant with the intricacies of molecular biology and its extensive technical vocabulary can be a challenge, though, as ... to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. ...
Backfiles - Biochemistry, Genetics and Molecular Biology
Continued as Progress in Biophysics and Molecular Biology. 1950-1962. 00796107. Progress in Biophysics and Molecular Biology. ... Continued as Insect Biochemistry and Molecular Biology. 1971-1991. 09651748. Insect Biochemistry and Molecular Biology. ... Molecular and Cell Biology of Lipids. 1965-1994. 09254439. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. ... Backfiles - Biochemistry, Genetics and Molecular Biology. Updated 10-Sep-2018 ISSN. Full Title. Change History. Year Range. ...
Biology W4065 :: Molecular Biology of Disease
Molecular Cell Biology; Kandel, E., et al, 2000. Principles of Neural Science; and two books of mine: Pollack: (1994), Signs of ... In any case I will steer the discussion to the molecular cause or mechanism underlying a disease or condition, and links of ... This course is designed to give students an opportunity learn on the some of the many molecular mechanisms of diseases caused ... These are on reserve in the Biology library, on the sixth floor of Fairchild. ...
Molecular Biology Web Book
Biochemistry and molecular biology
BMC Molecular Biology. BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in ... Biochemistry and Molecular Biology. Welcome to our Microbiology page where we highlight our most recent content, including ... Algorithms for Molecular Biology. *Derivative-free neural network for optimizing the scoring functions associated with ... BMC Molecular Biology. *Coincidence cloning recovery of Brucella melitensis RNA from goat tissues: advancing the in vivo ...
... hosts and expression tools for molecular research. On March 31, 2014 ATCC discontinued the ,a href=~/link.aspx?_id= ... ATCC is a trusted and reliable resource for molecular tools with a variety of vectors, ... Molecular Biology ATCC is a trusted and reliable resource for molecular tools with a variety of vectors, hosts and expression ... ATCC holdings include a variety of products to support Molecular Biology research and development. ...
The Molecular Theory of Radiation Biology | SpringerLink
DNA Strahlenbiologie Strahlenschaden aging biology cancer cell cell cycle chromosome cytology gene influence molecular ... the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA ... strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of ...
Virology Molecular Biology & Viral Therapy
... News-Medical. https://www.news-medical.net/health/Virology-Molecular-Biology-Viral ... Molecular biology of viruses. The viral genome contains all the information needed to initiate and complete an infectious cycle ... www.news-medical.net/health/Virology-Molecular-Biology-Viral-Therapy.aspx. ... www.news-medical.net/health/Virology-Molecular-Biology-Viral-Therapy.aspx,. ...
Molecular Cell Biology | IndieBound.org
Biology | Molecular Neurobiology | Amherst College
Molecular Neurobiology. Section Navigation. Sub Navigation. *Molecular Neurobiology Login for Additional Pages. Announcements ... Readings from primary literature will emphasize current molecular techniques utilized in the study of the nervous system. Three ... Requisite: Biology 19 and Chemistry 12. Limited to 30 students. Fall semester. Professor Graf. ... An analysis of the molecules and molecular mechanisms underlying nervous system function, development, and disease. We will ...
Molecular Biology Workshop
Announcing a Workshop on Methods in Molecular Biology at Oregon State University 1996 Offered by the Molecular and Cellular ... Molecular Biology Workshop. Katharine Field fieldk at ava.bcc.orst.edu Mon Apr 1 12:16:52 EST 1996 *Next message: q ... Gary Merrill, co-coordinator Faculty of the Molecular and Cellular Biology Program Housing: Housing in studio quad apartments ... Schedule: MCB 525 - Methods in Molecular Biology Session 1 July 15 - July 27, 1996 Session 2 September 9 - September 21, 1996 ...
Molecular, Cellular & Physiological Biology | California State University, Northridge
The Molecular, Cellular & Physiological Biology Area is proud of its many lab classes and the connection to biomedical research ... Chhandak Basu - plant cell and molecular biology, biotechnology Associate Professor. Ph.D., University of Rhode Island. email: ... Our work integrates molecular/cellular biology, signaling biochemistry, animal models of normal development and disease, and ... Biology. © California State University, Northridge 18111 Nordhoff Street, Northridge, CA 91330. Phone: (818) 677-1200 / Contact ...
Department of Biochemistry and Molecular Biology | UMass Amherst
Molecular Plant, 4(4):581 (2011). [PubMed]. Wang D, Griffitts J, Starker C, Fedorova E, Limpens E, Ivanov S, Bisseling T, and ... Current Biology, 17(20):1784 (2007). *: equal contribution[PubMed]. Sato M, Mitra R, Coller J, Wang D, Spivey N, Dewdney J, ... We aim to illuminate the molecular basis of highly evolved and intimate forms of symbiosis. Our system is the association ... Identifying these genes should lead to breakthroughs in understanding the molecular mechanisms of symbiosis. For example, one ...
Calculations for Molecular Biology and Biotechnology - 2nd Edition
Purchase Calculations for Molecular Biology and Biotechnology - 2nd Edition. Print Book & E-Book. ISBN 9780123756909, ... Any Biology student with an interest in Biotechnology or Molecular Biology and new Biotechnology technicians ... Calculations for Molecular Biology and Biotechnology 2nd Edition. A Guide to Mathematics in the Laboratory. ... Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an ...
Department of Biochemistry and Molecular Biology | UMass Amherst
My lab has now addressed these questions using biochemistry, structural biology and cell biology. We have found that CpdR ... Molecular Cell. Jul 2;59(1):104-16. [PubMed]. Smith SC, Joshi KJ, Zik JJ, Trinh K, Kamajaya A, Chien P*, Ryan KR*. (2014) Cell- ... Molecular Microbiology. Jun; 88(6):1083-92. [PubMed]. Rood KL, Clark NE, Stoddard PR, Garman SC, Chien P. (2012) Adaptor- ... Furthermore, as ClpX is a member of a larger class of other molecular machines whose primary role is to aid in the proper ...
Hydrogen Molecular Biology and Medicine | Xuejun Sun | Springer
This book provides a clearly structured introduction to hydrogen biology and medicine. Hydrogen is the one of the most abundant ... Hydrogen Molecular Biology and Medicine. Editors: Sun, Xuejun, Ohta, Shigeo, Nakao, Atsunori (Eds.) ... First book in the field of hydrogen biology and medicine. *Systematically introducing hydrogen biology from its physical and ... Shigeo Ohta is a professor from Department of Biochemistry and Cell Biology, Nippon Medical School. He is an expert in the ...
Molecular Biology in Clinical Oncology Workshop
Molecular Biology Maternity T-Shirts - CafePress
Molecular Biology,C449 - Undergraduate prospectus 2018
Related subjects Biology Molecular Biology Any questions?. Principal Admissions Tutor. Department of Molecular Biology and ... Molecular Biology MBiolSci. Department of Molecular Biology and Biotechnology. Apply for this course , ... Department of Molecular Biology and Biotechnology. We offer courses in biochemistry, genetics, molecular biology and ... Department of Molecular Biology and Biotechnology. 96% overall student satisfaction. Molecular Biology Biophysics and ...
Molecular and Developmental Biology Graduate Program
Cell biologyMechanismsMicrobiologyBiologicalBiochemistry and molecularLaboratoryBiotechnologyGenesSystems BiologyBioinformaticsFacultyGeneticImmunologyChemistryBiochemicalGenomicsPathwaysBiologistsLife sciencesPlant Molecular BiologyProcessesDevelopmentalProteinsNucleic acidCellular and molecularApproachesPhysiologyCancer biologyInteractionsCentral dogma oMethodsMoleculesOncologyStructural biologyBiomedicalUndergraduateResearch in molecular biology2020CellsTranscriptionEarly 2000sDiseasesFundamentalScienceGraduateCarcinogenesisUniversity
- Some clinical research and medical therapies arising from molecular biology are covered under gene therapy whereas the use of molecular biology or molecular cell biology in medicine is now referred to as molecular medicine . (wikipedia.org)
- Other branches of biology are informed by molecular biology, by either directly studying the interactions of molecules in their own right such as in cell biology and developmental biology , or indirectly, where molecular techniques are used to infer historical attributes of populations or species , as in fields in evolutionary biology such as population genetics and phylogenetics . (wikipedia.org)
- Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. (mit.edu)
- ATCC offers a variety of nucleic acid preparations from our Bacteriology, Mycology, Protistology, Virology, and Cell Biology collections. (atcc.org)
- This incubator supports a wide diversity of tissue, cell, and microbiological cultures and experiment methods to meet any spaceflight research experiment goals and objectives, including cell biology, microbiology, discovery biology, and drug-testing studies to be conducted on the ISS. (nasa.gov)
- With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, Molecular Cell Biology has justly earned an impeccable reputation as an authoritative and exciting text. (indiebound.org)
- Dr. Shigeo Ohta is a professor from Department of Biochemistry and Cell Biology, Nippon Medical School. (springer.com)
- Our laboratory was established in 2013 to undertake research combining cell biology, optical physics and biochemistry. (ucl.ac.uk)
- In cell biology we aim to understand how viruses enter cells, probing and remodelling membranes, and what are the structural changes viruses undergo during cell-entry, uncoating and morphogenesis. (ucl.ac.uk)
- To do so, we are developing new classes of fluorescent probes, high-speed cell friendly Super-Resolution (SR) methods and computational modelling approaches that, although designed to answer questions of interest in the lab, will have broad applications in cell biology research. (ucl.ac.uk)
- The overarching goal of our lab is to develop technology broadly applicable to research in cell biology. (ucl.ac.uk)
- Trends in Cell Biology. (sfu.ca)
- Read a description of the Structural Cell Biology Section . (nih.gov)
- Seeing (stem) cell biology with the eyes of Physics: perspective for a Regenerative Medicine without the needs for cell or tissue transplantation. (unibo.it)
- Welcome to the Department of Molecular Biology, Cell Biology & Biochemistry (MCB), which is the largest on-campus department in the Division of Biology and Medicine. (brown.edu)
- At Saint Mary's this discipline is covered in several upper division laboratory courses including Molecular Biology, Genetics, Microbiology, Immunology and Cell Biology after a firm introduction in our introductory course, Biology 1. (stmarys-ca.edu)
- You will acquire a solid understanding of all the key theories of biochemistry, cell biology, genetics and microbiology. (ruc.dk)
- In the junior and senior years, students progress from macromolecules to cellular metabolism to molecular genetics to cell biology. (centre.edu)
- Umeå University hosts many prominent research groups conducting strategic molecular research of international significance within areas of microbiology, cell biology, chemical biology, genetic model organisms, immunology, systems biology, sensory systems, cancer biology, developmental biology, medical biology and immunology. (umu.se)
- Specific entry requirements are: a) 60 ECTS in the Bioscience area (including genetics, microbiology, cell biology, molecular biology, zoo physiology and plant biology) and also including a minimum of 7.5 ECTS in each of Genetics and Microbiology. (umu.se)
- The Department of Cell Biology offers graduate training in cell biology and physiology leading to the Ph.D. degree. (gradschools.com)
- BS or MS or PhD with 1-2 years of experience in stem cell biology , cancer cell biology , molecular biology . (indeed.com)
- The Department of Molecular and Cell Biology (MCB) at the University of California at Berkeley offers outstanding opportunities for scientific training in a highly interactive environment that enables doctoral students to pursue any of a wide range of modern fields of biological research. (berkeley.edu)
- The Department of Molecular and Cell Biology is organized into five divisions and includes over 90 faculty. (berkeley.edu)
- The divisional organization offers the advantages of mid-sized, thematically focused, scientific groupings within the larger, more diverse academic environment in molecular and cell biology. (berkeley.edu)
- You will be equipped to meet admission requirements for advanced programs offering M.S. and Ph.D. degrees in areas ranging from molecular and cell biology to biochemistry and immunology, among others. (gcc.edu)
- The graduate curriculum consists of a multidisciplinary core that surveys the fundamental principles of biochemistry, molecular biology, cell biology, microbiology, immunology, pharmacology and physiology. (unt.edu)
- This scholarship is awarded annually for academic excellence to a student studying Molecular and Cell Biology at the third year level. (edu.au)
- The Scholarship will consist of financial support for a single year of tuition at the Honours level, if taken within a laboratory of the Molecular and Cell Biology Academic Group. (edu.au)
- I am intending to commence Honours (year 4) within a laboratory of the Molecular and Cell Biology Academic Group. (edu.au)
- This amount for 2017 is equal to the Commonwealth supported student contribution amount for 24 credit points of Molecular and Cell Biology subjects. (edu.au)
- The scholarship will be awarded to the student who has the highest total mark of all third year students studying third level subjects in Molecular and Cell Biology, calculated as the sum of their best two final marks in Molecular and Cell Biology subjects. (edu.au)
- It is named for Professor James Burnell, a long-standing member of the Molecular and Cell Biology Academic Group who taught extensively at the undergraduate level and mentored many Honours students. (edu.au)
- intend to commence an Honours program within a laboratory of the Molecular and Cell Biology Academic Group. (edu.au)
- the student with the highest total mark of all third year students studying Molecular and Cell Biology subjects at JCU at the third year level, calculated as the sum of their best two final marks in Molecular and Cell Biology subjects. (edu.au)
- The Department of Molecular Biology, Cell Biology, and Biochemistry is the largest on-campus department in the Division of Biology and Medicine. (brown.edu)
- The BSc (Hons) in Molecular Biology involves an introduction to the foundations of molecular and cellular biology and then focuses on topics such as chromosome structure and function, molecular genetics, molecular cell biology, biotechnology, bioinformatics, molecular virology and gene expression. (st-andrews.ac.uk)
- I've always been fascinated by molecular mechanisms of biological processes, and this is the best place to learn more about that. (asbmb.org)
- Molecular biology / m ə ˈ l ɛ k j ʊ l ər / is the branch of biology that concerns the molecular basis of biological activity in and between cells , including molecular synthesis, modification, mechanisms and interactions. (wikipedia.org)
- Molecular biology arose as an attempt to answer the questions regarding the mechanisms of genetic inheritance and the structure of a gene . (wikipedia.org)
- The Unit of Molecular Biology of Diseases is seeking a talented and highly motivated post-doctoral candidate in order to explore the molecular and cellular mechanisms underlying tumor development and progression. (nature.com)
- This course is designed to give students an opportunity learn on the some of the many molecular mechanisms of diseases caused by novel alleles, while not losing sight of other causes, in particular emergent infectious agents. (columbia.edu)
- Offered as BIOL 251 and BCBP 281) A study of the molecular mechanisms underlying the transmission and expression of genes. (amherst.edu)
- An analysis of the molecules and molecular mechanisms underlying nervous system function, development, and disease. (amherst.edu)
- We will also study the molecular mechanisms that control brain development, from neurogenesis, neurite growth and synaptogenesis to cell death and degeneration. (amherst.edu)
- In addition to analyzing neural function, throughout the course we will also study nervous system dysfunction resulting when such molecular mechanisms fail, leading to neurodevelopmental and neurodegenerative disease. (amherst.edu)
- The Developmental Oncogene Laboratory seeks to characterize the molecular mechanisms and normal or oncogenic functions of genes that play important roles during development but also contribute to cancer in the adult. (csun.edu)
- Researchers in computational biology and bioinformatics develop algorithms that can predict the behavior of a biological system and explore the molecular mechanisms of function of nucleic acids and/or proteins. (umassmed.edu)
- The Schiffer group uses molecular dynamics, detailed structural analysis, sequence analysis and structure based drug design to elucidate the molecular mechanisms by which mutations confer drug resistance and to develop strategies for avoiding drug resistance. (umassmed.edu)
- The Kelch lab uses molecular dynamics simulations and molecular modeling approaches to determine the structures and mechanisms of large complicated macromolecular machines. (umassmed.edu)
- The Weng lab is a leading analytical member of the ENCODE and psychENCODE consortia and has determined molecular mechanisms of gene regulation as well as how genetic variations in the human population affect gene regulation and susceptibility for diseases. (umassmed.edu)
- Specific research interests of the independent groups are interconnected by a common interest in fundamental and translational research concerning the molecular mechanisms of both bacterial and eukaryotic systems. (umu.se)
- Describe the molecular mechanisms that regulate gene expression, including epigenetics. (unibo.it)
- Describe the molecular mechanisms of cell fate determination and differentiation. (unibo.it)
- The broad goals of this research is to understand the cellular, molecular and genetic mechanisms that drive immunologically-mediated disorders. (cincinnatichildrens.org)
- This research increases our general knowledge of these processes and their molecular mechanisms, which is also of major importance for our understanding of a number of diseases. (ruc.dk)
- Students successfully completing this module should have developed a conceptual understanding of several aspects of Molecular Biology and Biochemistry, relevant for molecular mechanisms of disease. (bangor.ac.uk)
- Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). (routledge.com)
- The Molecular and Biology and Physiology (MBP) track is a broad track that covers the full spectrum of molecular and cellular mechanisms that underlie microbiological phenomena. (asm.org)
- The Characterizing Arabidopsis Root Attractions (CARA) experiment looks at mechanisms at the molecular and genetic level that influence the growth of a plant's roots in the absence of gravity, and how those change with or without light. (nasa.gov)
- Molecular biology, genetics, and epigenetics are rapidly expanding, enabling us to advance our knowledge of the underlying mechanisms involved. (mdpi.com)
- In order to better understand and assess the quality of ground and spring water, state-of-the-art methods from the fields of molecular biology and microbiology, as well as chemical high-performance analytics are now developed. (news-medical.net)
- This degree will give you a broad ranging knowledge of the molecular biosciences by allowing you to combine elements from our biochemistry, genetics and microbiology courses. (sheffield.ac.uk)
- Our fascinating BSc courses and accredited MBiolSci degrees span the bioscience subjects of biochemistry, genetics, microbiology and molecular biology. (sheffield.ac.uk)
- If you are eager to participate in biochemical, genetic, microbiology, molecular biology, or cellular biology research as a career, you will thrive in this program. (gcc.edu)
- 71 major credit hours of rigorous undergraduate coursework with classes focusing on genetics, developmental biology, microbiology, cancer biology, and other advanced topics. (gcc.edu)
- Students have the opportunity to engage with a number of specialist topics that reflect the research interests of the Biomedical Sciences Research Complex including, for example, molecular microbiology, marine and environmental biotechnology, molecular virology, chromosome replication, genome stability and chromatin structure and function. (st-andrews.ac.uk)
- JBC publishes high-quality science that seeks to elucidate the molecular and cellular basis of biological processes. (asbmb.org)
- Molecular analysis of virus genomes can be separated into two types of approach: physical analysis of structure and nucleotide sequence performed in vitro , and a more biological method to examine the structure-function relationships of intact virus genomes and individual genetic elements, generally involving analysis of the virus phenotype in vivo . (news-medical.net)
- Announcing a Workshop on Methods in Molecular Biology at Oregon State University 1996 Offered by the Molecular and Cellular Biology Program Oregon State University Corvallis, Oregon (541) 737-3799 An intensive training course for graduate students, faculty and researchers in the biological and medical sciences The methods of molecular biology, in particular recombinant DNA work, have transformed research in the biological and medical sciences. (bio.net)
- This course provides a hands-on introduction to molecular biological methods. (bio.net)
- Molecular Biological Investigations of Pheromone Desaturases, PBAN regulation of pheromone biosynthesis in female moths. (elsevier.com)
- The goal of computational biology and bioinformatics is to understand biology through the development of mathematical models, the use of computer simulation techniques and statistical analysis of large biological data-sets. (umassmed.edu)
- One of the current grand challenges in biology is bridging the gap between detailed gene/interaction lists and phenotypic, systems-level behaviors of biological networks. (ucl.ac.uk)
- Molecular Environmental Biology is the first book to illustrate molecular biological approaches to major issues in environmental biology. (routledge.com)
- Specific topics discussed include the use of molecular techniques in the population biology of wild animals and in the management of fisheries, bioremediation, cloning and characterization of the genes responsible for degradation of PCBs and related environmental pollutants, molecular analysis of aromatic hydrocarbon degradation by soil bacteria, and molecular biological techniques in assessing environmental damage to natural habitats. (routledge.com)
- Topics discussed in this area include an introduction to molecular epidemiology, the uses of molecular biological markers in cancer risk assessment, specific environmental carcinogens found in foods, measuring DNA adducts and mutation frequencies to assess environmental toxic exposures and effect, and using the extent of gene inducibility as a dosimeter of toxic exposure. (routledge.com)
- The Center for Computational Molecular Biology (CCMB) promotes the development, implementation and application of analytical and computational methods to foundational questions in the biological and medical sciences. (brown.edu)
- ASBMB publishes three journals: the Journal of Biological Chemistry, Journal of Lipid Research and Molecular and Cellular Proteomics. (asbmb.org)
- In the Master's programme in Molecular Biology you acquire an extensive toolbox for investigating all kinds of biological problems with advanced molecular methods. (umu.se)
- Molecular systems biology aims at understanding of biological phenomena based on the quantitative analysis of chemical and physical processes at the molecular level. (deds.nl)
- By its very nature, systems biology is a highly interdisciplinary approach towards understanding complex biological processes. (deds.nl)
- Molecular biology / m ə ˈ l ɛ k j ʊ l ər / is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell , including the interactions between DNA , RNA , proteins and their biosynthesis , as well as the regulation of these interactions. (wikipedia.org)
- Molecular biology /məˈlɛkjʊlər/ concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, and proteins and their biosynthesis, as well as the regulation of these interactions. (wikipedia.org)
- Demonstrate a competence in performing common molecular biological techniques (pipetting, dilution, setting up enzymatic reactions, polymerase chain reaction, gel electrophoresis, data recording and analysis) Demonstrate appropriate numerical and descriptive data analysis skills. (bangor.ac.uk)
- Knowledge of theoretical and practical molecular biology is necessary to understand and create new knowledge in biotechnology and biological and medical science. (uib.no)
- Molecular biology is also important for developing good data tools for the analysis of biological data. (uib.no)
- Molecular Biology belongs to the Department of Biological Sciences (BIO), which is situated on the Marineholmen campus close to the city centre. (uib.no)
- The focus of the Chemical Biology specialty section is on molecules and methods used to identify, visualize, probe or validate the biological functions of small molecules or biomolecules and their biological pathways. (frontiersin.org)
- Chemical Biology covers advances in a wide range of topics in the field, from new molecular tools and techniques, to their applications to address biological questions at the molecular or cellular level. (frontiersin.org)
- Characterizing Arabidopsis Root Attractions (CARA) advances the fundamental understanding of the molecular biological responses to extraterrestrial environments. (nasa.gov)
- In its formative years, molecular biology examined the chemical and physical structures of biological molecules, subsequently elucidated the nature and function of DNA and evolved into molecular genetics. (waterstones.com)
- Research focused on developing systems or integrative biological approaches to understanding basic cancer biology and related cellular and molecular processes. (cancer.gov)
Biochemistry and molecular10
- The American Society for Biochemistry and Molecular Biology helps you excel at all stages of your scientific career through networking, professional development, meetings, journals and leadership opportunities. (asbmb.org)
- The Biology and Biochemistry and Molecular Biology Chairs (or faculty designate) will inform the MCB Graduate Program Director of the 'target' number of Program students expected to be funded by Biology and BMB TAs. (umass.edu)
- Insect Pheromone Biochemistry and Molecular Biology covers how insects produce pheromones and how they detect pheromones and plant volatiles. (elsevier.com)
- Centre's program in biochemistry and molecular biology (BMB) is designed to provide a solid introduction to the cellular and molecular fundamentals of life. (centre.edu)
- he Department of Biochemistry and Molecular Biology offers a program of study leading to the Ph.D. degree. (gradschools.com)
- This is followed by advanced courses that focus on the most recent progress in specific areas of biochemistry and molecular biology to provide the student with a contemporary perspective in the fields of greatest current interest. (unt.edu)
- The qualifying examination ensures that a doctoral student has sufficient mastery of fundamental principles of biochemistry and molecular biology to be successful as a PhD candidate and, subsequently, as an independent researcher. (unt.edu)
- The qualifying examination is administered by biochemistry and molecular biology faculty, excluding for the student's major professor, and in an oral examination format. (unt.edu)
- During the examination, the questioning/discussions may be expanded to address related topics in the field of biochemistry and molecular biology. (unt.edu)
- The student must demonstrate an ability to discuss and apply concepts of biochemistry and molecular biology in a broader context. (unt.edu)
- Founded in 1974, EMBL is Europe's flagship laboratory for the life sciences - an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology. (embl.de)
- The Basic Molecular Biology eLearning Series provides online training for public health and clinical laboratory professionals by introducing the scientific background for molecular diagnosis, the principles of molecular biology laboratory practice, and common methods. (cdc.gov)
- The basic Molecular Biology series includes four eLearning courses: Basic Science, Laboratory Practice, Nucleic Acid Extraction, and PCR and Real-Time PCR. (cdc.gov)
- This basic-level eLearning course provides information on molecular biology laboratory practices. (cdc.gov)
- The Newborn Screening and Molecular Biology Branch (NSMBB) has the only laboratory in the world devoted to ensuring the accuracy of newborn screening tests in every state and more than 80 countries. (cdc.gov)
- NSQAP works with other programs in the NSMBB: the Biochemical Mass Spectrometry Laboratory, the Newborn Screening Translation Research Laboratory, and the Molecular Quality Improvement Program. (cdc.gov)
- This includes program-tailored guidance for laboratory-specific needs and help in evaluating ongoing and future molecular testing procedures. (cdc.gov)
- CDC's Newborn Screening and Molecular Biology Branch (NSMBB) has been granted ISO/IEC 17043 accreditation by the American Association for Laboratory Accreditation (A2LA) External External . (cdc.gov)
- The four-year MBiolSci has Advanced Accreditation from the Royal Society of Biology, has more focus on laboratory skills, and includes an extensive research project, which can be based in a university or industrial lab. (sheffield.ac.uk)
- Read a description of the Laboratory of Cell and Molecular Biology . (nih.gov)
- Sidney Frank Hall of Life Sciences is a five-story, 169,000-square-foot glass and brick structure devoted to the study of human biology and the Laboratory of Molecular Medicine that houses laboratories of faculty drawn from five basic science departments of the Brown Medical School, and two cutting edge research centers. (brown.edu)
- The laboratory exercises entail modern experimental techniques to solve relevant questions in Molecular Biology. (umu.se)
- The Source Book was originally published by the Cold Spring Harbor Laboratory Press to supply essential information on sources of reagents and supplies to users of the well-known Molecular Cloning Manuals published by CSHLP. (bio.net)
- Grove City College offers a molecular biology major that emphasizes the development of your skills in the laboratory. (gcc.edu)
- The Department of Molecular Biology & Immunology houses facilities featuring state-of-the art Center for Commercialization of Fluorescence Technologies , Advanced Mass Spectrometry and Proteomics Laboratory and Flow Cytometry and Laser Capture Microdissection Core Facility . (unt.edu)
- Molecular Biology at St Andrews incorporates substantial practical laboratory training and development of quantitative skills. (st-andrews.ac.uk)
- This course is one of a range of courses in the molecular biosciences offered by the Department of Molecular Biology and Biotechnology. (sheffield.ac.uk)
- With a Master of Science Degree in Molecular Biology you are attractive for employers at, for example, pharmaceutical and biotechnology companies, usually within research, development or marketing. (umu.se)
- The Department of Biochemistry & Molecular Biology offers programs leading to MS, PhD, and MD/PhD degrees, preparing students for successful careers as independent investigators in academia, government, biotechnology, and in teaching in academia, govern. (gradschools.com)
- And available computational/analytical tools in molecular biology , genetics, development, and biotechnology required. (indeed.com)
- Molecular genetics and recombinant DNA technology for the manipulation of genes. (edu.au)
- Reiter JF, Leroux MR. Genes and molecular pathways underpinning ciliopathies. (sfu.ca)
- Even though Molecular Biology is an elusive term and therefore a difficult field of study to define, here at Saint Mary's, we enjoy simplicity, and choose to define it classically, as the study of the structure and activity of genes at the molecular level. (stmarys-ca.edu)
- Molecular Biology is the part of biology that concerns itself with macromolecules' properties and interactions, and examines the function of genes and the function of the proteins that are formed. (ruc.dk)
- In molecular and cellular biology, traditional research is dedicated to unravel acute functional relevance of proteins and genes, as well as mechanistic insights into their long-term role in signal transduction. (umcutrecht.nl)
- This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. (mit.edu)
- Systems biology analyses and integrates complex molecular processes. (deds.nl)
- Systems biology approaches involve quantitative modeling of molecular systems. (deds.nl)
- This iterative approach combining modeling and wet lab experiments is typical for systems biology. (deds.nl)
- Professor Henry Heng's team, from the medical school at Wayne State University, has published a perspective article titled A Systems Biology Perspective on Molecular Cytogenetics to address the issue. (eurekalert.org)
- In this article, they applied the genome theory to explain why cytogenetics/cytogenomics needs a systems biology perspective, while systems biology itself needs a cytogenetic/cytogenomic based platform, since genome context (karyotype) represents a new type of genomic coding. (eurekalert.org)
- Thus, systems biology should not exclusively focus on parts collection, but study how to predict system behavior at the proper genomic levels: the understanding of lower-level parts has very limited power to understand the emergence at higher system levels when the entire system is highly complex. (eurekalert.org)
- The integration of cytogenetics/cytogenomics with systems biology will mutually benefit both fields. (eurekalert.org)
- We need to develop efficient algorithm and use systems biology concept to analyze them. (utdallas.edu)
- Much of molecular biology is quantitative, and recently a significant amount of work has been done using computer science techniques such as bioinformatics and computational biology . (wikipedia.org)
- What is Computational Biology and Bioinformatics ? (umassmed.edu)
- The BMP department has expertise in many different areas, and computational biology and bioinformatics are key or central components for many of our studies. (umassmed.edu)
- Much of molecular biology is quantitative, and recently much work has been done at its interface with computer science in bioinformatics and computational biology . (wikipedia.org)
- Based on the results of these selection processes, the Biology and BMB Chairs (or faculty designate) match the wishes of the instructors and TAs as far as possible and circulate tentative assignments. (umass.edu)
- Staff: Dr. Katharine Field, Coordinator Dr. Walt Ream, co-coordinator Dr. Gary Merrill, co-coordinator Faculty of the Molecular and Cellular Biology Program Housing: Housing in studio 'quad' apartments (single rooms with shared kitchen and bath) is available close to campus at a cost of $185 for two weeks. (bio.net)
- The Department of Molecular Biology is unique, being affiliated to both the Faculty of Science and Technology and to the Faculty of Medicine. (umu.se)
- In the fall of 2006, I joined the faculty of the newly-formed Department of Molecular and Cellular Biology. (uoguelph.ca)
- The research programs of the Core Faculty in CCMB lie fundamentally at the intersection of computer science, evolutionary biology, mathematics, and molecular and cellular biology. (brown.edu)
- Welcome to master's studies in Molecular biology at the Faculty of Mathematics and Natural Sciences. (uib.no)
- Newly revised and updated, the Fourth Edition is a comprehensive guide through the basic molecular processes and genetic phenomena of both prokaryotic and eukaryotic cells. (google.com)
- The Use of Molecular Genetic Techniques to Address Conservation Questions (M.W. Bruford and R.K. Wayne). (routledge.com)
- Viswanathan, C. & Zhu, J.K. Molecular genetic analysis of cold-regulated gene transcription. (nature.com)
- The central dogma of molecular biology where genetic material is transcribed into RNA and then translated into protein , despite being oversimplified, still provides a good starting point for understanding the field. (wikipedia.org)
- By using molecular and genetic tools, fundamental questions regarding the signals that affect how a root knows to grow toward gravity and/or in the opposite direction of the shoot may be answered. (nasa.gov)
- BCHM 218 is a foundational course to the study of molecular biology, focusing on the structural and functional properties and relationships of DNA, RNA and proteins, particularly the processes required to reliably pass genetic information from DNA to RNA to protein, and from one generation to the next. (queensu.ca)
- The new field of Artificial Chemistries draws from chemistry, biology, computer science, mathematics, and other disciplines to work toward that goal. (mit.edu)
- The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. (news-medical.net)
- Requisite: Biology 19 and Chemistry 12. (amherst.edu)
- The BMB major begins in the first-year/sophomore years with a solid foundation in biology, chemistry, mathematics, and physics. (centre.edu)
- You can do your project either in a research group at Umeå University, for example in the departments of Molecular Biology, Chemistry or Plant Physiology, but other arrangements with research intense organisations like biotech companies are also possible. (umu.se)
- It is an interdisciplinary section devoted to all aspects of chemical biology, a rapidly growing field at the interface of chemistry and biology as well as related biomedical fields. (frontiersin.org)
- College degree in chemistry, biochemistry or biology , with math skills capable of calculating buffer preparation and dilution. (indeed.com)
- Students with undergraduate science majors in biology, chemistry and biochemistry that fulfill prerequisite courses of organic and inorganic chemistry will be considered for admission. (unt.edu)
- This book describes the new productive association between novel state- of-the-art molecular biology and crop protection, a discipline with a sound heritage in traditional applied biology and chemistry. (waterstones.com)
- BMC Biochemistry is an open access, peer-reviewed journal that considers articles on all aspects of biochemical processes, including the structure, function and dynamics of metabolic pathways, supramolecular complexes, enzymes, proteins, nucleic acids and small molecular components of organelles, cells and tissues. (biomedcentral.com)
- Research projects employ state-of-the-art molecular and biochemical techniques utilizing proteomics, mass spectrometry, advanced fluorescence spectroscopy and optical imaging. (unt.edu)
- Laboratories for Molecular Medicine (LMM) houses the other half of MCB labs along with the Genomics Core Facility, Structural Biology Core Facility, & the Transgenic Mouse Facility. (brown.edu)
- The Center of Computational Molecular Biology and the Center for Genomics and Proteomics. (brown.edu)
- This course introduces you to the basic biology of modern genomics and the experimental tools that we use to measure it. (coursera.org)
- In this review, we describe the most recent discoveries in the molecular and cellular biology of RMS, including alterations in oncogenic pathways, miRNA (miR), in vivo models, stem cells, and important signal transduction cascades implicated in the development and progression of RMS. (hindawi.com)
- The Department is devoted to cutting-edge research that addresses basic questions in biology, including the control of gene expression, cell fate determination, protein synthesis, the genetics of behavior, control of the cell cycle, and signaling pathways within the cell. (brown.edu)
- It is important to identify and understand the molecular pathways of the metastatic cascade in order to target the investigation and development of more effective therapies and research directions. (mdpi.com)
- The Department is devoted to cutting-edge research that addresses basic questions in biology, including the control of gene expression, cell fate determination, protein synthesis, the genetics of behavior, control of the cell cycle, signaling pathways within the cell, and the role of prions in cellular activity. (brown.edu)
- To help molecular biologists specifically identify each strand individually, the two strands are usually differentiated as the "sense" strand and the "antisense" strand. (wikipedia.org)
- In addition, daily lectures by molecular biologists will provide theoretical background and insight into cutting-edge research developments and techniques. (bio.net)
- Medical, pharmaceutical and biotechnological industry and research are also relevant fields of work for molecular biologists. (uib.no)
Plant Molecular Biology2
- Molecular biology is the study of the molecular underpinnings of the processes of replication , transcription , translation , and cell function. (wikipedia.org)
- We will explore the proteins that contribute to the unique structure and function of neurons, including an in-depth analysis of synaptic communication and the molecular processes that modify synapses. (amherst.edu)
- The Molecular & Developmental Biology Graduate Program at Cincinnati Children's Hospital Medical Center offers a unique opportunity to participate in cutting-edge research while being embedded in one of the top three pediatric hospitals in the nation. (cincinnatichildrens.org)
- The MCB PhD program at Brandeis provides supportive and close-knit community conducting internationally recognized research at the frontiers of molecular, cell, developmental, chemical and neurobiology. (brandeis.edu)
- The Massi group uses computer simulations to understand the fundamental aspects of molecular recognition and binding specificity of RNA binding proteins that regulate the stability of mRNA transcripts encoding key cancer-related proteins. (umassmed.edu)
- The Massi lab has determined the molecular origin of the order/disorder transition in the TIS11 family of RNA-binding proteins and characterized how this structural transition affects the activity of these proteins in the cell. (umassmed.edu)
- In molecular biology and genetics , the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA , refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids . (wikipedia.org)
- The BioToolKit, a searchable and browsable database of 400 internet research applications, includes up-to-date links to nucleic acid, genome, and protein databases, online applications for data retrieval and data analysis, and tools for molecular visualization. (bio.net)
- Molecular biology skills including nucleic acid isolation and purification, PCR, qPCR, and molecular cloning techniques. (indeed.com)
Cellular and molecular1
- This collection describes key approaches in sparse modeling, focusing on its applications in fields including neuroscience, computational biology, and computer vision. (mit.edu)
- The book also explores how new molecular approaches can be applied to human disease etiology and epidemiology. (routledge.com)
- Molecular Epidemiologic Approaches in Environmental Carcinogenesis (R.M. Santella and F.P. Perera). (routledge.com)
- Research in our department employs a range of cross-disciplinary approaches, including state of the art optical tools for confocal and electron microscopy, physical technologies such as X-ray diffraction, and innovative techniques in molecular biology. (brown.edu)
- Unique interactions between the brain's micro-environment, blood-brain barrier, and tumor cells are hypothesized to promote distinct molecular features in CNS metastases that may require tailored therapeutic approaches. (mdpi.com)
- Research approaches using cell lines that preferentially metastasize in vivo to the brain and in vitro tissue-based studies unfold new molecular leads into the disease. (mdpi.com)
- From this exponential growth of scientific knowledge, tremendous opportunities were created for the application of molecular approaches to solve problems in applied biology. (waterstones.com)
- This research area supports new approaches and methods for characterizing and perturbing genomes, epigenomes, proteomes, glycomes, and metabolomes, as well as methods for other high-throughput molecular characterizations. (cancer.gov)
- Explore our research by subject - from microbes & parasites to cancer biology. (umu.se)
- My research continues to investigate the molecular basis of signal transduction, with an emphasis on understanding aspects of embryonic development, kidney function, blood vessel formation, cancer biology and nervous system patterning. (uoguelph.ca)
- The Division of Molecular Radiation Biology's mission is to educate and train the next cadre of scientists and clinicians in the disciplines of radiation and cancer biology and to execute a multidisciplinary program of research focused on understanding the molecular, cellular, and organismal responses to ionizing radiation exposure for the betterment of humankind. (utsouthwestern.edu)
- Research in structural biology and molecular applications allows for the development of methods and technologies that lead to discoveries in a variety of areas in cancer biology. (cancer.gov)
- Nuclear function, cytoskeleton and cell membrane interactions, transport of cellular products between different organelles fits in the Cellular Biology category. (springer.com)
- Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated. (news-medical.net)
- Understanding the molecular basis of these interactions is therefore a significant challenge in biology, and it is of key importance in defining how certain mutations can lead to pathological conditions such as kidney disease and cancer. (uoguelph.ca)
- Ultimately, this should result in a full understanding of cells, tissues and organisms in terms of molecular interactions. (deds.nl)
Central dogma o2
- The central dogma of molecular biology describes the process in which DNA is transcribed into RNA then translated into protein. (wikipedia.org)
- We'll introduce the Central Dogma of Molecular Biology and cover how next-generation sequencing can be used to measure DNA, RNA, and epigenetic patterns. (coursera.org)
- While researchers practice techniques specific to molecular biology, it is common to combine these with methods from genetics and biochemistry . (wikipedia.org)
- The introduction of high-throughput methods has transformed biology into a data-rich science. (mit.edu)
- Application of modern molecular methods to biomedical and agricultural problems will also be considered. (amherst.edu)
- Schedule: MCB 525 - Methods in Molecular Biology Session 1 July 15 - July 27, 1996 Session 2 September 9 - September 21, 1996 This is a highly intensive training course, requiring a full-time committment from the participants. (bio.net)
- International experts have contributed representative chapters that cover how molecular methods and concepts apply to wildlife management, ecology, pollution control and remediation, and environmental health. (routledge.com)
- Products belonging to the quality grade BioUltra for molecular biology are wellsuited for all commonly used basic experimental methods in the field of molecular cloning. (sigmaaldrich.com)
- The development, testing, and early validation of wet lab technologies, computer-based methods and data science, and device and systems development are all enabled by research in structural biology and molecular applications. (cancer.gov)
- For patterning networks, molecular ensembles must sense and transduce spatial information such as position, direction and distance, which requires integrating information over length scales orders of magnitude larger than the molecules themselves. (ucl.ac.uk)
- In this lecture, we're going to talk about molecular biology structures, by which I mean structures in the DNA and other molecules inside the cell that you need to know about to understand the rest of the course. (coursera.org)
- This volume of Molecular Biology of Hematopoiesis is dedicated to many inter- national scientists and clinicians for their contribution to the field of Hematology/ Oncology presented at the 11th International Symposium on Molecular Biology of Hematopoiesis, which was held in Bormio, Italy, June 25-29, 1998. (springer.com)
- Hematopoiesis, molecular biology, and molecular oncology including mouse modeling of hematopoiesis, myelopoiesis and leukemia. (cincinnatichildrens.org)
- The Molecular, Cellular & Physiological Biology Area is proud of its many lab classes and the connection to biomedical research. (csun.edu)
- Importantly, our biomedical research probes the molecular basis of several human disorders arising from ciliary dysfunction, including Bardet-Biedl Syndrome and Meckel syndrome. (sfu.ca)
- The graduate program in the Department of Biology provides students with the training they need to excel in academic or biomedical research careers. (gradschools.com)
Research in molecular biology1
- BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of chromatin, replication, recombination, mutation, repair, transcription, translation and RNA processing and function. (biomedcentral.com)
- The module also contains 6 practical days on applied molecular methodologies covering a range of key technologies (reverse transcription, PCR, agarose gel electrophoresis, protein expression and SDS-PAGE). (bangor.ac.uk)
- and the development of molecular probes to identify and characterize potential therapeutic targets, such as enzymes, receptors, transcription factors, nucleic acids, and others, and their use in drug discovery. (frontiersin.org)
- This basic-level eLearning course provides information on the fundamental characteristics of DNA and RNA, nucleotide base-pairing rules, and the basic techniques and workflow applied in molecular diagnostics. (cdc.gov)
- Applications range from fundamental biology investigations to commercial drug discovery efforts. (nasa.gov)
- At a fundamental level, molecular biology looks at life from a molecular perspective - how it started and how it keeps going. (uib.no)
- While molecular biology was established as an official branch of science in the 1930s, the term wasn't coined until 1938 by Warren Weaver . (wikipedia.org)
- The autumn admission to The Master of Science Programme in Molecular Biology begins with a course in Advanced Molecular Biology. (umu.se)
- Apart from this, you are free to select from a number of different courses in Molecular Biology or in other subjects as long as they fulfil the requirements to obtain The Master of Science Degree in Molecular Biology. (umu.se)
- Molecular Biology" is defined by both an approach (a way to do life science) and a subject (a way to think about life science). (wesleyan.edu)
- The MCB Graduate Program Director informs the Biology and BMB Chairs of the names of students he wishes to have TA support. (umass.edu)
- With a molecular biology degree from Grove City College, you will be prepared to score highly on the MCAT, DAT, GRE, or OAT and land competitive positions or entry into prestigious medical schools and graduate programs. (gcc.edu)
- V. V. Artym, A. L. Kindzelskii, W. T. Chen, and H. R. Petty, "Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on β 1 integrins and the cytoskeleton," Carcinogenesis , vol. 23, no. 10, pp. 1593-1602, 2002. (hindawi.com)
- The following year he moved to Harvard University, where he became Professor of Biology, a post he held until 1976. (google.com)
- Molecular Biology is a subject which you will study as a part of your bachelor programme at Roskilde University. (ruc.dk)
- Master's projects in Molecular Biology cover a wide professional range and are carried out in different research groups and departments at the university but also at the University Hospital and Institute of Marine Research. (uib.no)
- With a master's degree in molecular biology you can work with research and teaching at universities, university colleges, university hospitals and other major hospitals. (uib.no)