AnatomyOrganismsDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Mitral ValveMitral Valve ProlapseMitral Valve InsufficiencyMitral Valve StenosisAortic ValveMitral Valve AnnuloplastyHeart Valve DiseasesChordae TendineaeAortic Valve StenosisTricuspid ValveHeart Valve Prosthesis ImplantationHeart Valve ProsthesisAortic Valve InsufficiencyBioprosthesisPulmonary ValveEchocardiography, TransesophagealRheumatic Heart DiseaseEchocardiographyEchocardiography, Three-DimensionalCardiac Surgical ProceduresCardiac Valve AnnuloplastyPhonocardiographyEndocarditis, BacterialTricuspid Valve InsufficiencyEndocarditisEchocardiography, Doppler, ColorVenous ValvesHeart AuscultationEchocardiography, DopplerCatheterizationTreatment OutcomeCardiac CatheterizationProlapseReoperationMyxomaPapillary MusclesProsthesis DesignHeart AtriaHeart RuptureSuture TechniquesFollow-Up StudiesHeart NeoplasmsPostoperative ComplicationsCalcinosisHeart VentriclesKinetocardiographyHeart MurmursProsthesis FailureCardiopulmonary BypassBalloon ValvuloplastyHeart Defects, CongenitalHemodynamicsThoracotomyPulmonary Valve StenosisVentricular Outflow ObstructionHeart SoundsTime FactorsSeverity of Illness IndexVentricular Function, LeftAtrial FibrillationMarfan SyndromeHeart ValvesSternotomyCardiomyopathy, HypertrophicRetrospective StudiesSurgical Procedures, Minimally InvasiveHeart InjuriesAngiocardiographyThromboembolismEndocardial Cushion DefectsModels, CardiovascularPericardiumStroke VolumeCardiovascular Surgical ProceduresHeart SeptumPostoperative PeriodSurgical InstrumentsHeart DiseasesProspective StudiesHeart AneurysmRupture, SpontaneousDiastoleSystoleCineradiographyThoracic SurgerySternumLutembacher SyndromeEndocardial FibroelastosisDevice RemovalHeart Septal Defects, VentricularFibromaVentricular Dysfunction, LeftHeart Septal Defects, AtrialElectrocardiographyAtrial Function, LeftEmbolismFeasibility StudiesHeart Septal DefectsThrombosisTricuspid Valve ProlapseIleocecal ValveEquipment DesignCoronary Artery BypassAnemia, HemolyticBlood Flow VelocityPredictive Value of TestsMyocardial ContractionRisk AssessmentRecurrencePulmonary VeinsProsthesis-Related InfectionsRisk FactorsSheep
Mitral Valve: The valve between the left atrium and left ventricle of the heart.Mitral Valve Prolapse: Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.Mitral Valve Stenosis: Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.Aortic Valve: The valve between the left ventricle and the ascending aorta which prevents backflow into the left ventricle.Mitral Valve Annuloplasty: A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annulus of the MITRAL VALVE. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).Chordae Tendineae: The tendinous cords that connect each cusp of the two atrioventricular HEART VALVES to appropriate PAPILLARY MUSCLES in the HEART VENTRICLES, preventing the valves from reversing themselves when the ventricles contract.Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.Tricuspid Valve: The valve consisting of three cusps situated between the right atrium and right ventricle of the heart.Heart Valve Prosthesis Implantation: Surgical insertion of synthetic material to repair injured or diseased heart valves.Heart Valve Prosthesis: A device that substitutes for a heart valve. It may be composed of biological material (BIOPROSTHESIS) and/or synthetic material.Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).Bioprosthesis: Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. Durability is achieved 1, mechanically by the interposition of a cloth, usually polytetrafluoroethylene, between the host and the graft, and 2, chemically by stabilization of the tissue by intermolecular linking, usually with glutaraldehyde, after removal of antigenic components, or the use of reconstituted and restructured biopolymers.Pulmonary Valve: A valve situated at the entrance to the pulmonary trunk from the right ventricle.Echocardiography, Transesophageal: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues using a transducer placed in the esophagus.Rheumatic Heart Disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.Echocardiography: Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.Echocardiography, Three-Dimensional: Echocardiography amplified by the addition of depth to the conventional two-dimensional ECHOCARDIOGRAPHY visualizing only the length and width of the heart. Three-dimensional ultrasound imaging was first described in 1961 but its application to echocardiography did not take place until 1974. (Mayo Clin Proc 1993;68:221-40)Cardiac Surgical Procedures: Surgery performed on the heart.Cardiac Valve Annuloplasty: A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annuli of HEART VALVES. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.Phonocardiography: Graphic registration of the heart sounds picked up as vibrations and transformed by a piezoelectric crystal microphone into a varying electrical output according to the stresses imposed by the sound waves. The electrical output is amplified by a stethograph amplifier and recorded by a device incorporated into the electrocardiograph or by a multichannel recording machine.Endocarditis, Bacterial: Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.Tricuspid Valve Insufficiency: Backflow of blood from the RIGHT VENTRICLE into the RIGHT ATRIUM due to imperfect closure of the TRICUSPID VALVE.Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.Echocardiography, Doppler, Color: Echocardiography applying the Doppler effect, with the superposition of flow information as colors on a gray scale in a real-time image.Venous Valves: Flaps within the VEINS that allow the blood to flow only in one direction. They are usually in the medium size veins that carry blood to the heart against gravity.Heart Auscultation: Act of listening for sounds within the heart.Echocardiography, Doppler: Measurement of intracardiac blood flow using an M-mode and/or two-dimensional (2-D) echocardiogram while simultaneously recording the spectrum of the audible Doppler signal (e.g., velocity, direction, amplitude, intensity, timing) reflected from the moving column of red blood cells.Catheterization: Use or insertion of a tubular device into a duct, blood vessel, hollow organ, or body cavity for injecting or withdrawing fluids for diagnostic or therapeutic purposes. It differs from INTUBATION in that the tube here is used to restore or maintain patency in obstructions.Treatment Outcome: Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.Cardiac Catheterization: Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.Prolapse: The protrusion of an organ or part of an organ into a natural or artificial orifice.Reoperation: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.Myxoma: A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)Papillary Muscles: Conical muscular projections from the walls of the cardiac ventricles, attached to the cusps of the atrioventricular valves by the chordae tendineae.Prosthesis Design: The plan and delineation of prostheses in general or a specific prosthesis.Heart Atria: The chambers of the heart, to which the BLOOD returns from the circulation.Heart Rupture: Disease-related laceration or tearing of tissues of the heart, including the free-wall MYOCARDIUM; HEART SEPTUM; PAPILLARY MUSCLES; CHORDAE TENDINEAE; and any of the HEART VALVES. Pathological rupture usually results from myocardial infarction (HEART RUPTURE, POST-INFARCTION).Suture Techniques: Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).Follow-Up Studies: Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.Heart Neoplasms: Tumors in any part of the heart. They include primary cardiac tumors and metastatic tumors to the heart. Their interference with normal cardiac functions can cause a wide variety of symptoms including HEART FAILURE; CARDIAC ARRHYTHMIAS; or EMBOLISM.Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.Calcinosis: Pathologic deposition of calcium salts in tissues.Heart Ventricles: The lower right and left chambers of the heart. The right ventricle pumps venous BLOOD into the LUNGS and the left ventricle pumps oxygenated blood into the systemic arterial circulation.Kinetocardiography: The graphic recording of chest wall movement due to cardiac impulses.Heart Murmurs: Heart sounds caused by vibrations resulting from the flow of blood through the heart. Heart murmurs can be examined by HEART AUSCULTATION, and analyzed by their intensity (6 grades), duration, timing (systolic, diastolic, or continuous), location, transmission, and quality (musical, vibratory, blowing, etc).Prosthesis Failure: Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.Cardiopulmonary Bypass: Diversion of the flow of blood from the entrance of the right atrium directly to the aorta (or femoral artery) via an oxygenator thus bypassing both the heart and lungs.Balloon Valvuloplasty: Widening of a stenosed HEART VALVE by the insertion of a balloon CATHETER into the valve and inflation of the balloon.Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.Hemodynamics: The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM.Thoracotomy: Surgical incision into the chest wall.Pulmonary Valve Stenosis: The pathologic narrowing of the orifice of the PULMONARY VALVE. This lesion restricts blood outflow from the RIGHT VENTRICLE to the PULMONARY ARTERY. When the trileaflet valve is fused into an imperforate membrane, the blockage is complete.Ventricular Outflow Obstruction: Occlusion of the outflow tract in either the LEFT VENTRICLE or the RIGHT VENTRICLE of the heart. This may result from CONGENITAL HEART DEFECTS, predisposing heart diseases, complications of surgery, or HEART NEOPLASMS.Heart Sounds: The sounds heard over the cardiac region produced by the functioning of the heart. There are four distinct sounds: the first occurs at the beginning of SYSTOLE and is heard as a "lubb" sound; the second is produced by the closing of the AORTIC VALVE and PULMONARY VALVE and is heard as a "dupp" sound; the third is produced by vibrations of the ventricular walls when suddenly distended by the rush of blood from the HEART ATRIA; and the fourth is produced by atrial contraction and ventricular filling.Time Factors: Elements of limited time intervals, contributing to particular results or situations.Severity of Illness Index: Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.Ventricular Function, Left: The hemodynamic and electrophysiological action of the left HEART VENTRICLE. Its measurement is an important aspect of the clinical evaluation of patients with heart disease to determine the effects of the disease on cardiac performance.Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.Heart Valves: Flaps of tissue that prevent regurgitation of BLOOD from the HEART VENTRICLES to the HEART ATRIA or from the PULMONARY ARTERIES or AORTA to the ventricles.Sternotomy: Making an incision in the STERNUM.Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).Retrospective Studies: Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.Surgical Procedures, Minimally Invasive: Procedures that avoid use of open, invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device.Heart Injuries: General or unspecified injuries to the heart.Angiocardiography: Radiography of the heart and great vessels after injection of a contrast medium.Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.Endocardial Cushion Defects: A spectrum of septal defects involving the ATRIAL SEPTUM; VENTRICULAR SEPTUM; and the atrioventricular valves (TRICUSPID VALVE; BICUSPID VALVE). These defects are due to incomplete growth and fusion of the ENDOCARDIAL CUSHIONS which are important in the formation of two atrioventricular canals, site of future atrioventricular valves.Models, Cardiovascular: Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment.Pericardium: A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs: the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.Stroke Volume: The amount of BLOOD pumped out of the HEART per beat, not to be confused with cardiac output (volume/time). It is calculated as the difference between the end-diastolic volume and the end-systolic volume.Cardiovascular Surgical Procedures: Surgery performed on the heart or blood vessels.Heart Septum: This structure includes the thin muscular atrial septum between the two HEART ATRIA, and the thick muscular ventricular septum between the two HEART VENTRICLES.Postoperative Period: The period following a surgical operation.Surgical Instruments: Hand-held tools or implements used by health professionals for the performance of surgical tasks.Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.Prospective Studies: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.Heart Aneurysm: A localized bulging or dilatation in the muscle wall of a heart (MYOCARDIUM), usually in the LEFT VENTRICLE. Blood-filled aneurysms are dangerous because they may burst. Fibrous aneurysms interfere with the heart function through the loss of contractility. True aneurysm is bound by the vessel wall or cardiac wall. False aneurysms are HEMATOMA caused by myocardial rupture.Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.Diastole: Post-systolic relaxation of the HEART, especially the HEART VENTRICLES.Systole: Period of contraction of the HEART, especially of the HEART VENTRICLES.Cineradiography: Motion picture study of successive images appearing on a fluoroscopic screen.Thoracic Surgery: A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.Sternum: A long, narrow, and flat bone commonly known as BREASTBONE occurring in the midsection of the anterior thoracic segment or chest region, which stabilizes the rib cage and serves as the point of origin for several muscles that move the arms, head, and neck.Lutembacher Syndrome: A condition characterized by a combination of OSTIUM SECUNDUM ATRIAL SEPTAL DEFECT and an acquired MITRAL VALVE STENOSIS.Endocardial Fibroelastosis: A condition characterized by the thickening of ENDOCARDIUM due to proliferation of fibrous and elastic tissue, usually in the left ventricle leading to impaired cardiac function (CARDIOMYOPATHY, RESTRICTIVE). It is most commonly seen in young children and rarely in adults. It is often associated with congenital heart anomalies (HEART DEFECTS CONGENITAL;) INFECTION; or gene mutation. Defects in the tafazzin protein, encoded by TAZ gene, result in a form of autosomal dominant familial endocardial fibroelastosis.Device Removal: Removal of an implanted therapeutic or prosthetic device.Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.Fibroma: A benign tumor of fibrous or fully developed connective tissue.Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.Heart Septal Defects, Atrial: Developmental abnormalities in any portion of the ATRIAL SEPTUM resulting in abnormal communications between the two upper chambers of the heart. Classification of atrial septal defects is based on location of the communication and types of incomplete fusion of atrial septa with the ENDOCARDIAL CUSHIONS in the fetal heart. They include ostium primum, ostium secundum, sinus venosus, and coronary sinus defects.Electrocardiography: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.Atrial Function, Left: The hemodynamic and electrophysiological action of the LEFT ATRIUM.Embolism: Blocking of a blood vessel by an embolus which can be a blood clot or other undissolved material in the blood stream.Feasibility Studies: Studies to determine the advantages or disadvantages, practicability, or capability of accomplishing a projected plan, study, or project.Heart Septal Defects: Abnormalities in any part of the HEART SEPTUM resulting in abnormal communication between the left and the right chambers of the heart. The abnormal blood flow inside the heart may be caused by defects in the ATRIAL SEPTUM, the VENTRICULAR SEPTUM, or both.Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.Tricuspid Valve Prolapse: Abnormal protrusion of one or more of the leaflets of TRICUSPID VALVE into the RIGHT ATRIUM during SYSTOLE. This allows the backflow of blood into right atrium leading to TRICUSPID VALVE INSUFFICIENCY; SYSTOLIC MURMURS. Its most common cause is not primary valve abnormality but rather the dilation of the RIGHT VENTRICLE and the tricuspid annulus.Ileocecal Valve: The valve, at the junction of the CECUM with the COLON, that guards the opening where the ILEUM enters the LARGE INTESTINE.Equipment Design: Methods of creating machines and devices.Coronary Artery Bypass: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.Anemia, Hemolytic: A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES).Blood Flow Velocity: A value equal to the total volume flow divided by the cross-sectional area of the vascular bed.Predictive Value of Tests: In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test.Myocardial Contraction: Contractile activity of the MYOCARDIUM.Risk Assessment: The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)Recurrence: The return of a sign, symptom, or disease after a remission.Pulmonary Veins: The veins that return the oxygenated blood from the lungs to the left atrium of the heart.Prosthesis-Related Infections: Infections resulting from the implantation of prosthetic devices. The infections may be acquired from intraoperative contamination (early) or hematogenously acquired from other sites (late).Risk Factors: An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent.Sheep: Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.

Chordal force distribution determines systolic mitral leaflet configuration and severity of functional mitral regurgitation. (1/2148)

OBJECTIVES: The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND: Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these have to comply with the chordal force distribution defined by the chordal coapting forces (F(c)) created by the transmitral pressure difference, which close the leaflets and the chordal tethering forces (FT) pulling the leaflets apart. METHODS: Porcine mitral valves (n = 5) were mounted in a left ventricular model where leading edge chordal forces measured by dedicated miniature force transducers were controlled by changing left ventricular pressure and papillary muscle position. Chordae geometry and occlusional leaflet area (OLA) needed to cover the leaflet orifice for a given leaflet configuration were determined by two-dimensional echo and reconstructed three-dimensionally. Occlusional leaflet area was used as expression for incomplete leaflet coaptation. Regurgitant fraction (RF) was measured with an electromagnetic flowmeter. RESULTS: Mixed procedure statistics revealed a linear correlation between the sum of the chordal net forces, sigma[Fc - FT]S, and OLA with regression coefficient (minimum - maximum) beta = -115 to -65 [mm2/N]; p < 0.001 and RF (beta = -0.06 to -0.01 [%/N]; p < 0.001). Increasing FT by papillary muscle malalignment restricted leaflet mobility, resulting in a tented leaflet configuration due to an apical and posterior shift of the coaptation line. Anterior leaflet coapting forces increased due to mitral leaflet remodeling, which generated a nonuniform regurgitant orifice area. CONCLUSIONS: Altered chordal force distribution caused functional mitral regurgitation based on tented leaflet configuration as observed clinically.  (+info)

Changes in porcine transmitral flow velocity pattern and its diastolic determinants during partial coronary occlusion. (2/2148)

OBJECTIVES: To define the mechanical determinants of transmitral flow and the effect of heart rate during regional ischemia. BACKGROUND: Myocardial ischemia changes the transmitral flow velocity pattern due to disease-induced changes in the heart's diastolic properties. METHODS: Regional ischemia was produced in 12 pigs by partially occluding the left anterior descending coronary artery until segment-length shortening in the ischemic region fell by 20%. Transmitral flow velocity patterns and their determinants were measured under two conditions, baseline and ischemia, at two heart rates, 70 and 90 beats/min. RESULTS: Regional ischemia had a significant effect on two determinants of filling: relaxation, which was slower, and chamber stiffness, which increased. These changes were associated with reduced contractility and increased myocardial stiffness, resulting in an early transmitral flow pattern that was flatter and narrower, but no change in the late flow pattern. Moderate increases in heart rate accelerated relaxation and decreased atrioventricular pressure gradient but had no effect on contractility or myocardial or chamber stiffness, resulting in an early transmitral flow pattern that was flatter and narrower and an increased late flow velocity. CONCLUSIONS: This model of regional ischemia leads to a flatter and narrower early transmitral flow velocity pattern and no change in late flow due to a combination of slowed left ventricular relaxation and increased chamber stiffness. Reflex increases in heart rate that accompany ischemia tend to mask this effect.  (+info)

Effects of permanent dual-chamber pacing on mitral regurgitation in hypertrophic obstructive cardiomyopathy. (3/2148)

AIMS: To assess the effects of chronic dual-chamber pacing on mitral regurgitation in hypertrophic obstructive cardiomyopathy. METHODS AND RESULTS: Twenty-three patients with hypertrophic obstructive cardiomyopathy and mitral regurgitation. treated with DDD pacing for 16 +/- 14 months, were included in the study. Mitral regurgitation was assessed by Doppler-echocardiography using semi-quantitative analysis (grades I-IV) and by measuring the maximum regurgitant jet area/left atrial area ratio. At the end of follow-up, DDD pacing reduced the outflow gradient from 93 +/- 37 mmHg to 31 +/- 30 mmHg (P<0.0001). Nine of the 14 patients who initially had > or =grade II mitral regurgitation improved by at least one grade, two of them exhibiting dramatic improvement (from grade IV and III to grade I). The regurgitant jet area/left atrial area ratio was reduced with DDD pacing from 20 +/- 13% to 11 +/- 6% (P<0.0001). Patients who had significant mitral regurgitation despite pacing were those whose outflow gradient remained high or those with mitral valve organic abnormalities (mitral annulus calcification or mitral valve prolapse). In the absence of organic abnormalities other than leaflet elongation, there was a significant correlation between the gradient value achieved with DDD pacing and the extent of mitral regurgitation (P<0.05). CONCLUSION: In the absence of organic mitral valve abnormalities, DDD pacing reduces in parallel mitral regurgitation and left ventricular outflow gradient. In such patients therefore, significant mitral regurgitation is not a contraindication to pacing.  (+info)

Perivalvular abscesses associated with endocarditis; clinical features and prognostic factors of overall survival in a series of 233 cases. Perivalvular Abscesses French Multicentre Study. (4/2148)

AIMS: The purposes of this study were to determine the clinical features and to identify prognostic factors of abscesses associated with infective endocarditis. METHODS AND RESULTS: During a 5-year period from January 1989, 233 patients with perivalvular abscesses associated with infective endocarditis were enrolled in a retrospective multicentre study. Of the patients, 213 received medical surgical therapy and 20 medical therapy alone. No causative microorganism could be identified in 31% of cases. Sensitivity for the detection of abscesses was 36 and 80%, respectively using transthoracic and transoesophageal echocardiography. Surgical treatment consisted of primary suture of the abscess (38%), insertion of a felt aortic or mitral ring using Teflon or pericardium (42%), or debridment of the abscess cavity (20%). The 1 month operative mortality was 16%. Actuarial rates for overall survival at 3 and 27 months in operated patients were 75 +/- 10% and 59 +/- 11%, respectively. Increasing patient age, staphylococcal infection, and fistulization of the abscess were found to be independent risk factors in both 1 month and overall operative mortality. Renal failure was a risk factor predictive of operative mortality at 1 month, whereas uncontrolled infection and circumferential abscess were regarded as risk factors predictive of overall operative mortality. CONCLUSION: The data determined prognostic factors of abscesses associated with infective endocarditis.  (+info)

Intraoperative left ventricular perforation with false aneurysm formation. (5/2148)

Two cases of perforation of the left ventricle during mitral valve replacement are described. In the first case there was perforation at the site of papillary muscle excision and this was recognized and successfully treated. However, a true ventricular aneurysm developed at the repair site. One month after operation rupture of the left ventricle occurred at a second and separate site on the posterior aspect of the atrioventricular ring. This resulted in a false aneurysm which produced a pansystolic murmur mimicking mitral regurgitation. Both the true and the false aneurysm were successfully repaired. In the second case perforation occurred on the posterior aspect of the atrioventricular ring and was successfully repaired. However, a false ventricular aneurysm developed and ruptured into the left atrium producing severe, but silent, mitral regurgitation. This was recognized and successfully repaired. The implications of these cases are discussed.  (+info)

Echocardiographic diagnosis of large fungal verruca attached to mitral valve. (6/2148)

In a patient with endocarditis due to Candida tropicalis echocardiograms from mitral valve vegetations were found to mimic the typical pattern of a left atrial myxoma. A mass was shown occupying the mitral orifice posterior to the anterior mitral leaflet; densities also appeared in the left atrium. Though these echocardiographic findings were consistent with the diagnosis of a left atrial myxoma, there were other distinctive differential diagnostic features. Other diagnostic possibilities must, therefore, be considered in the interpretation of echocardiograms which suggest left atrial tumour.  (+info)

Long-term clinical and echocardiographic follow-up after percutaneous mitral valvuloplasty with the Inoue balloon. (7/2148)

BACKGROUND: The objective of this study was to assess the long-term clinical outcome and valvular changes (area and regurgitation) after percutaneous mitral valvuloplasty (PMV). METHODS AND RESULTS: After PMV, 561 patients were followed up for 39 (+/-23) months and clinical/echocardiographic data obtained yearly. Kaplan-Meier and Cox regression analyses were performed to estimate event-free survival, its predictors, and the relative risks of several patient subgroups. There were several nonexclusive events: 19 (3.3%) cardiac deaths, 55 (9.8%) mitral replacements, 6 (1%) repeated PMVs, 56 (10%) cases of restenosis, and 108 (19%) cases of clinical impairment. Survival free of major events (cardiac death, mitral surgery, repeat PMV, or functional impairment) was 69% at 7 years, ranging from 88% to 40% in different subgroups of patients. Wilkins score was the best preprocedural predictor of mitral opening, but the procedural result (mitral area and regurgitation) was the only independent predictor of major event-free survival. Mitral area loss, though mild [0.13 (+/-0.21)cm2], increased with time and was >/=0.3 cm2 in 12%, 22%, and 27% of patients at 3, 5, and 7 years, respectively. Regurgitation did not progress in 81% of patients, and when it occurred it was usually by 1 grade. CONCLUSIONS: Seven years after PMV, more than two thirds of patients were in good clinical condition and free of any major event. The procedural result was the main determinant of long-term outcome, although a high score had also negative implications. Mitral area decreased progressively over time, whereas regurgitation did not tend to progress.  (+info)

Mobile echoes on prosthetic valves are not reproducible. Results and clinical implications of a multicentre study. (8/2148)

AIMS: To test the hypothesis that inter-observer variability accounts for the wide variation in reported prevalences of fibrin strands on prosthetic heart valves and to develop criteria for their identification and reporting. METHODS AND RESULTS: A videotape with 30 sequences of prosthetic heart valves imaged by transoesophageal echocardiography and showing abnormalities such as strands, microbubbles, and spontaneous echocardiographic contrast, was assessed in 13 European and three American centres. There were three duplicated examples, unbeknown to the observers. Definitions and reported prevalence rates of the abnormalities were analysed, and inter- and intra-observer agreement estimated with the kappa statistic. Mobile echoes were identified in 40 to 80% of the sequences on the tape. The reported prevalence of mobile echoes correlated with the time spent reporting the tape. There was moderate inter-observer agreement for the identification of any mobile echoes (kappa = 0.38), but no agreement for their labelling (kappa = 0.22), in spite of similar definitions. Intra-observer reproducibility was good (agreement in 76% of the reduplicated sequences). CONCLUSIONS: The true prevalence and potential significance of mobile echoes on prosthetic heart valves cannot be assessed unless inter-observer consensus on echocardiographic criteria for identifying such echoes is reached.  (+info)

Double Orifice Mitral Valve ~ JPEEI CLINICDouble Orifice Mitral Valve ~ JPEEI CLINIC
Double orifice mitral valve (DOMV) without mitral regurgitation or mitral stenosis are asymptomatic. Physical findings may only exist if mitral regurgitation or mitral stenosis are present.. The severity of symptoms depends on the degree of left atrial hypertension. Dyspnea, nocturnal cough, and tachypnea occur, related to pulmonary venous congestion and increased lung stiffness. Frequent respiratory infections and wheezing occur, secondary to pulmonary congestion, increased fluid exudation, and airway narrowing. Poor feeding, failure to thrive, fatigue and sweating occur because of heart failure and reduced cardiac output. On occasion, a child with double orifice mitral valve presents with acute pulmonary edema or generalized edema. Hemoptysis and syncope can occur in older patients with double orifice mitral valve.. Double orifice mitral valve is detected in one of 3 ways. As an associated lesion with other congenital heart defects, especially in the presence of atrioventricular (AV) septal ...
Advances in the understanding of the pathogenesis, progression and diagnosis of myxomatous mitral valve disease in dogsAdvances in the understanding of the pathogenesis, progression and diagnosis of myxomatous mitral valve disease in dogs
BURCHELL, Richard K. and SCHOEMAN, Johan. Advances in the understanding of the pathogenesis, progression and diagnosis of myxomatous mitral valve disease in dogs. J. S. Afr. Vet. Assoc. [online]. 2014, vol.85, n.1, pp.01-05. ISSN 2224-9435.. A number of key questions remain unanswered in the pathogenesis of myxomatous mitral valve disease (MMVD). As MMVD typically afflicts small-breed dogs, a genetic basis has been implied. In addition, the fact that not all dogs within a risk group develop MMVD is still unexplained. Research into the pathogenesis of MMVD typically falls under three categorical divisions, namely genetic factors, mechanical factors of the valve and systemic factors. Genetic studies have implicated certain loci in the pathogenesis of MMVD. Of particular interest is the insulin-like growth factor (IGF)-1 locus, as IGF-1 is also associated with growth. The mechanical structure and function of the mitral valve have also received much attention in recent years. What has emerged is the ...
Medical management of myxomatous mitral valve disease: An evidence-based veterinary medicine approachMedical management of myxomatous mitral valve disease: An evidence-based veterinary medicine approach
BURCHELL, Richard K. y SCHOEMAN, Johan. Medical management of myxomatous mitral valve disease: An evidence-based veterinary medicine approach. J. S. Afr. Vet. Assoc. [online]. 2014, vol.85, n.1, pp.01-07. ISSN 2224-9435. http://dx.doi.org/10.4102/jsava.v85i1.1095.. Myxomatous mitral valve disease (MMVD) is the most common heart disease of dogs. The current management of MMVD in dogs is mostly pharmacological, and the recommendations for treatment are based on a number of veterinary studies. Notwithstanding the current consensus regarding the medical management of MMVD, there remains active debate as to which drugs are the most effective. In order to understand how recommendations are constructed in the pharmacological management of diseases, the veterinarian needs to understand the concept of evidence-based veterinary medicine, and how the findings of these studies can be applied in their own practices. This review summarises the current veterinary literature and explains how the consensus ...
Mitral Valve RegurgitationMitral Valve Regurgitation
Your blood is supposed to follow a one-way path through your heart. It flows in through the top chamber (the left atrium), down to the bottom chamber (the left ventricle), and then out to your body. Your mitral valve separates these two chambers and keeps the blood from flowing backward. In mitral valve regurgitation, your mitral valve does not work as it should and allows blood to flow backward into your upper heart chamber.. Mitral valve regurgitation can happen suddenly (acute) or, more commonly, gradually over time (chronic). Acute mitral valve regurgitation is often caused by damage to the heart, perhaps from a heart attack or a heart infection called endocarditis. There are many possible reasons you can develop chronic mitral valve regurgitation, including mitral valve prolapse, rheumatic heart disease and untreated high blood pressure. If you have mitral valve regurgitation, you may notice that you feel very tired and that you have a hard time catching your breath when you exercise or ...
Patente US6875224 - Devices and methods for percutaneous mitral valve repair - Google PatentesPatente US6875224 - Devices and methods for percutaneous mitral valve repair - Google Patentes
Devices and methods are provided for diagnosing and repairing mitral valve defects such as mitral valve regurgitation. According to an exemplary method, mitral valve function is visualized by transesophageal echocardiography. A catheter is inserted along the venous system of the patient through the atrium into the mitral valve. A suction tip grasps the leaflets of the mitral valve to immobilize and juxtapose the leaflets at a point simulating a stitch, and the mitral valve is again observed to confirm that fastening at that point will repair the prolapse or other defect. The mitral valve leaflets are then via a fastening such as a staple or shape memory rivet. The fastener may be inserted by a stapling assembly in the venous catheter tip, or by a separate stapler that is inserted along an arterial path from the opposite direction and guided along a transcardiac rail to the immobilized point. Upon completion of the repair process, the mitral valve is once again visualized by transesophageal
Long-term results of suture annuloplasty for degenerative mitral valve disease: A propensity-matched analysis<...Long-term results of suture annuloplasty for degenerative mitral valve disease: A propensity-matched analysis<...
TY - JOUR. T1 - Long-term results of suture annuloplasty for degenerative mitral valve disease. T2 - A propensity-matched analysis. AU - Garatti, Andrea. AU - Canziani, Alberto. AU - Parolari, Alessandro. AU - Castelvecchio, Serenella. AU - Guazzi, Marco. AU - Daprati, Andrea. AU - Farah, Ali Abu. AU - Grimaldi, Francesco. AU - Tripepi, Sonia. AU - Menicanti, Lorenzo. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Aims Ring annuloplasty is the gold standard of surgical repair in degenerative mitral valve disease. However, prosthetic annuloplasty has some drawbacks and potential hazards. Suture annuloplasty theoretically is able to preserve annular leaflet dynamics and left ventricular performance, but experience is limited. The aim of the study was to review the early and long-term outcome of the posterior double-suture annuloplasty (DSA) technique for degenerative mitral valve repair. Methods From January 2002 to December 2008, 400 patients underwent primary mitral valve repair for degenerative disease ...
Minimally Invasive Mitral Valve Surgery: The Evidence | CTSNetMinimally Invasive Mitral Valve Surgery: The Evidence | CTSNet
It was a very good discussion on minimally invasive Mitral valve surgery. Everyone is talking about a right sided mini thoracotomy. For the Mitral valve, we forget that the Mitral valve is a left sided structure and the Left Atrium is a posterior structure. We, particularly in India have been used to approaching the Mitral through the left side for a Closed Mitral Valvotomy. Now we can accomplish arterial and venous return through excellent groin cannulation available today. Since most of the Mitral valve patients are relatively young, the concern for atherosclerosis emboli should be minimal. When one does the procedure through the left side, the Mitral valve is closer to the surgeon and the surgery can be accomplished through routine instruments. One does not need knot tiers and knot pushers. From the right side, the Mitral valve is at a fair distance from the incision and one loses the tactile sensation. Advantages of approaching the Mitral valve through the left side are 1. Easy and secure ...
Echocardiography Tutorial - Mitral ValveEchocardiography Tutorial - Mitral Valve
The mitral valve lies between the left atrium and the left ventricle and has two leaflets, the anterior and the posterior. In the figures below, the anterior leaflet is colored green and the posterior leaflet is colored blue. The corresponding video clips show the motion of the valve through the cardiac cycle, but the leaflets are not colored. The images in the left column show the mitral valve directly visualized from the left ventricle, where the chordae tendinae of the subvalvular apparatus can be appreciated. The middle images are taken using transthoracic echocardiography in a 2 chamber, long axis view of the mitral valve. The images on the right are taken of the anterior and posterior leaflets in a short axis view of the heart taken at the level of the mitral valve annulus using transthoracic echocardiography. Applications such as color flow echocardiography allow for the visualization of flow through the mitral valve. Other anatomical features of the mitral valve that can be visualized ...
Edge-to-Edge Mitral Valve Repair Without Ring Annuloplasty for Acute Ischemic Mitral Regurgitation | CirculationEdge-to-Edge Mitral Valve Repair Without Ring Annuloplasty for Acute Ischemic Mitral Regurgitation | Circulation
IMR continues to be a clinical challenge, and the best surgical treatment for this ever-increasing patient population remains to be defined. Alfieri edge-to-edge mitral repair along with mitral ring annuloplasty partially eliminates ischemic and functional mitral regurgitation.10,12 However, no large series of patients with IMR treated with this technique has been reported, and the efficacy of Alfieri repair without ring annuloplasty is unknown. This acute ovine experiment revealed that the Alfieri repair did not prevent acute IMR. Furthermore, it did not alter the annular, subvalvular, and leaflet geometric distortions associated with acute ischemia.. Acute posterolateral ischemia in sheep results in annular dilatation and larger SL annular diameter,18 similar to that reported here. However, the mitral CC diameter increase, has not been observed previously and may be because of the acute, open-chest nature of this experiment. Interestingly, the annular geometric changes during ischemia did not ...
Patent US20030144697 - Fixed length anchor and pull mitral valve device and method - Google PatentsPatent US20030144697 - Fixed length anchor and pull mitral valve device and method - Google Patents
A device effects the mitral valve annulus geometry of a heart. The device includes a first anchor configured to be positioned within and anchored to the coronary sinus of the heart adjacent the mitral valve annulus within the heart and a second anchor configured to be positioned within the coronary sinus of the heart proximal to the first anchor and adjacent the mitral valve annulus within the heart. The second anchor, when deployed, anchors against distal movement and is moveable in a proximal direction. The device further includes a connecting member having a fixed length permanently attached to the first and second anchors. As a result, when the first and second anchors are within the coronary sinus with the first anchor anchored in the coronary sinus, the second anchor may be displaced proximally to effect the geometry of the mitral valve annulus and released to maintain the effect on the mitral valve geometry.
Mitral valve closure in atrial flutter. | CirculationMitral valve closure in atrial flutter. | Circulation
12 patients who had atrial flutter without clinical, echocardiographic or angiographic evidence of aortic insufficiency were studied with simultaneous echo- and phonocardiograms. In patients with high-grade atrioventricular (AV) block, the mitral valve opened and closed with each flutter wave. Of seven patients, two had persistent and five had intermittent early mitral valve closure before QRS inscription. In five patients (three with 2:1 AV block) the mitral valve closed on time. In one patient with a mitral valve prosthesis, echocardiography and cinefluorography demonstrated closure during mid-diastole, with reopening in late diastole after a flutter wave. Final valve closure occurred before the onset of the QRS, and each closure was associated with a click. Simultaneous phonocardiographic analysis in these patients demonstrated that the first heart sound intensity was inversely related to the degree of mitral valve preclosure. This relationship was independent of the length of the RR ...
Percutaneous Mitral Valve Repair With the Edge-to-Edge Technique | JACC: Journal of the American College of CardiologyPercutaneous Mitral Valve Repair With the Edge-to-Edge Technique | JACC: Journal of the American College of Cardiology
The paper by Feldman et al. (1) in this issue of the Journalis the first published report about a new percutaneous mitral valve technology, the edge-to-edge Evalve clip (Evalve Inc., Menlo Park, California). This is an important step into a new era of catheter-based valve procedures and one that will be compared and contrasted with the ongoing excellent surgical results obtained with mitral valve repair of the myxomatous regurgitant mitral valve. The investigators, who are among the leading cardiac interventionalists in the country, have performed a carefully thought out phase I U.S. Food and Drug Administration safety trial of 27 low-risk patients with myxomatous valve disease, a group of patients for whom surgical repair of the mitral valve is safe and effective. They have clearly documented the safety of this procedure, and have also documented that there is a significant learning curve as it relates to fluoroscopy time, echocardiography time, and anesthesia time. The investigators have been ...
Transesophageal echocardiography during mitral valve repair underestimates mitral valve area by pressure half-time calculation ...Transesophageal echocardiography during mitral valve repair underestimates mitral valve area by pressure half-time calculation ...
Background: Mitral valve repair (MVRr) has become the mainstay of surgical treatment for mitral valvular regurgitation. Evaluation of MVRr by intraoperative transesophageal echocardiography (IOE) has been routinely employed to guide the operation. While the main objective of IOE is to assess for residual mitral regurgitation, it is also important to exclude significant mitral stenosis. Utilisation of pressure half-time (PHT) to estimate mitral valve area (MVA) has been shown to be reliable in normal clinical situations. However, in MVRr, the accuracy of MVA calculation by PHT needs to be ascertained. Methods and results: Data from IOE and post-MVRr transthoracic echocardiography (TTE) from the year 1998 to 2002 were analysed and when required, offline PHT measurements were made. The mean time interval between the two echocardiographic examinations was 10.6 (1 to 56) weeks. In our 36 cases, the IOE MVA was found to be 2.1 ± 0.5 cm 2, with the corresponding TTE MVA to be 2.7 ± 1.0 cm 2. MVA by ...
Mitral Valve Repair or Replacement: Before Your SurgeryMitral Valve Repair or Replacement: Before Your Surgery
Mitral valve surgery can repair or replace your hearts mitral valve. The new valve may be mechanical or made of animal tissue, often from a pig. Your doctor will talk with you before surgery about which type of valve is best for you.. The mitral valve opens and closes to keep blood flowing in the proper direction through your heart. When the mitral valve does not close properly (mitral valve regurgitation) or is very tight and narrow (mitral valve stenosis), blood does not flow through the heart the right way.. You will be asleep during the surgery. The doctor will make a cut (incision) in the skin over your breastbone (sternum). Then the doctor will cut through your sternum to reach your heart.. The doctor will connect you to a heart-lung bypass machine, which is used to add oxygen to your blood and move the blood through your body. This machine will allow the doctor to stop your heartbeat while he or she works on your heart.. While your heartbeat is stopped, the doctor will repair or replace ...
Mitral Valve Repair | Cardiac Surgery in the Adult, 5e | AccessCardiology | McGraw-Hill MedicalMitral Valve Repair | Cardiac Surgery in the Adult, 5e | AccessCardiology | McGraw-Hill Medical
It can be reasonably argued that the very dawn of cardiac surgery began with a mitral valve repair. On May 20, 1923, Dr Elliot Carr Cutler (Fig. 35-1) performed the worlds first successful mitral valve repair at the Peter Bent Brigham Hospital in Boston, Massachusetts.1 Dr Cutler carried out a transventricular mitral valve commissurotomy with a neurosurgical tenotomy knife on a critically ill 12-year-old girl. His choice of instrument was likely influenced by Dr Harvey Cushing who was surgeon-in-chief at the time. A new era in surgery was introduced as well as the reality of mitral valve repair.2 Cutler had worked assiduously on this problem in the Surgical Research Laboratories of Harvard Medical School before turning his attention to this critically ill patient. Subsequent attempts at this operation using a device to cut out a segment of the diseased mitral valve resulted in several deaths from massive mitral regurgitation and Cutler eventually abandoned the procedure.3 Of Cutlers ...
Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery - Full Text...Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery - Full Text...
The purpose of this study is to determine whether the addition of surgical ablation to planned mitral valve surgery for patients with persistent or longstanding persistent AF (within 6 months prior to randomization) reduces the incidence of postoperative heart arrhythmia compared to mitral valve repair with medication therapy alone. This is a randomized, multi-center trial which will enroll 260 subjects who will be randomized in a 1:1 fashion to: (a) mitral valve surgery plus surgical ablation or (b) mitral valve surgery without ablation (control group). All patients will undergo ligation or excision of the left atrial appendage. Patients assigned to the ablation group will be further randomized (1:1) to one of two lesion sets: (1) pulmonary vein isolation only or (2) biatrial Maze lesions. The target population for this trial consists of adult patients with mitral valve disease requiring surgical intervention and persistent or longstanding persistent atrial fibrillation. All patients who meet ...
Left atrial isolation for the treatment of atrial fibrillation due to mitral valve disease. Hemodynamic evaluation<...Left atrial isolation for the treatment of atrial fibrillation due to mitral valve disease. Hemodynamic evaluation<...
TY - JOUR. T1 - Left atrial isolation for the treatment of atrial fibrillation due to mitral valve disease. Hemodynamic evaluation. AU - Graffigna, A.. AU - Ressia, L.. AU - Pagani, F.. AU - Minzioni, G.. AU - Vigano, M.. PY - 1993. Y1 - 1993. N2 - Ablation of atrial fibrillation secondary to mitral valve disease is frequently impossible after isolated mitral valve surgery. In order to improve sinus rhythm recovery in such patients, patients with rheumatic mitral valve disease and chronic atrial fibrillation underwent surgical electrophysiological isolation of the left atrium at the time of surgery. The left atrium is left free to fibrillate, beat or stand still, while the right atrium recovers its sinus activation and warrants a regular ventricular rate. Apart from this advantage, we tested the hypothesis that the recovery of right atrial booster function could significantly improve cardiac output. From May 1989 to July 1993 184 patients with mitral with or without other valve disease ...
Influence of Chronic Tethering of the Mitral Valve on Mitral Leaflet Size and Coaptation in Functional Mitral Regurgitation |...Influence of Chronic Tethering of the Mitral Valve on Mitral Leaflet Size and Coaptation in Functional Mitral Regurgitation |...
Our study shows that: 1) the mitral leaflet coaptation decreased proportionally in patients with FMR related to the bilateral PM displacement, despite increased total leaflet area to compensate for the increased mitral annular area and mitral leaflet tethering; 2) annular area was significantly smaller and leaflet-to-annular area ratio was significantly larger in patients with global LV remodeling who have nonsignificant FMR compared with the patients with significant FMR; and 3) the indexes of coaptation were related to MR severity.. FMR is produced by a complex combination of pathophysiological processes where distorted and spherical LV geometry leads to tethering of the chordae and therefore incomplete leaflet coaptation (8,10,21). In this condition, patients with mitral leaflet tethering have been shown to have larger mitral leaflet area than the control subjects (10). Similarly, Dal-Bianco et al. (22) demonstrated that mechanical stresses imposed by PM tethering increased MV leaflet area ...
Mount Sinai Investigators Find Greater Life Expectancy and Durability in Patients Who Received Mitral Valve Operations from...Mount Sinai Investigators Find Greater Life Expectancy and Durability in Patients Who Received Mitral Valve Operations from...
May 2, 2017 /Press Release/ -- Patients can maximize chances of high-quality mitral valve repair through referral to surgeons with large annual repair rates. Surgeons who perform more than 25 mitral valve operations a year are more likely to perform repairs that are durable, and their patients are more likely to be alive a year after the operation, than when operations are performed by lower-volume surgeons, an Icahn School of Medicine at Mount Sinai study has found.. The results of the study will be presented at the American Association for Thoracic Surgery Centennial meeting on Tuesday, May 2, in Boston and published online simultaneously in the Journal of the American College of Cardiology. The study is the first to highlight that patients operated on by higher volume mitral surgeons experienced lower one year mortality and rates of reoperations compared to those operated by low volume mitral surgeons.. Mitral valve repair is the recommended treatment for patients with severe degenerative ...
Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG)...Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG)...
CAD occurs when the arteries that supply blood to the heart become blocked as a result of plaque buildup. In severe cases, CAD can cause chest pain, shortness of breath, and heart attack. CABG is one treatment option for people with CAD. During a CABG procedure, a healthy artery or vein from another part of the body is connected to the blocked coronary artery. Blood flow is then routed around the blockage to the heart.. After a heart attack, some people may have a leak in the mitral valve of the heart. This condition is known as ischemic mitral regurgitation (IMR) and is associated with poor health outcomes, including worsening heart failure. In people with severe mitral valve leakage, the CABG procedure and a mitral valve repair procedure are routinely performed together; however, in people with only moderate valve leakage, there is no consensus in the medical community as to whether the mitral valve repair procedure is beneficial at the time of CABG. The purpose of this study is to determine ...
DEGENERATIVE MITRAL VALVE DISEASE | Hursts The Heart, 14e | AccessCardiology | McGraw-Hill MedicalDEGENERATIVE MITRAL VALVE DISEASE | Hurst's The Heart, 14e | AccessCardiology | McGraw-Hill Medical
The normal mitral valve permits one-way blood flow from the left atrium to the left ventricle in an efficient, nearly frictionless fashion.1 Although even a normal competent valve may allow a trivial amount of reversed flow, more than a trace of mitral regurgitation is considered pathologic.2 Mild-to-moderate mitral regurgitation is tolerated indefinitely as long as it does not worsen. However, severe mitral regurgitation causes left ventricular remodeling reduced forward cardiac output, neurohumoral activation, left ventricular damage, heart failure, and ultimately death.3 The natural history of mitral regurgitation depends intimately on its etiology, the severity of left ventricular volume overload as well as its contractile performance, and the appearance of overlapping clinical conditions secondary to reversal flow, such as atrial fibrillation and pulmonary hypertension.4 In this setting, myxomatous degeneration of the mitral valve, a very common pathologic substrate of mitral valve ...
Procedural Guidance Using Advance Imaging Techniques for Percutaneous Edge-to-Edge Mitral Valve Repair | SpringerLinkProcedural Guidance Using Advance Imaging Techniques for Percutaneous Edge-to-Edge Mitral Valve Repair | SpringerLink
The complexity of structural heart disease interventions such as edge-to edge mitral valve repair requires integration of multiple highly technical imaging modalities. Real time imaging with...
Repeated mitral valve replacement in a patient with extensive annular calcification | Journal of Cardiothoracic Surgery | Full...Repeated mitral valve replacement in a patient with extensive annular calcification | Journal of Cardiothoracic Surgery | Full...
Mitral valve replacement in the presence of severe annular calcification is a technical challenge. A 47-year-old lady who had undergone mitral and aortic valve replacement for rheumatic disease 27 years before presented with dyspnea. At reoperation, extensive mitral annular calcification was hindering the disc motion of the Starr-Edwards mitral prosthesis. The old prosthesis was removed and a St Jude Medical mechanical valve was implanted after thorough annular debridement. Postoperatively the patient developed paravalvular leak and hemolytic anemia, subsequently undergoing reoperation three days later. The mitral valve was replaced with an Edwards MIRA valve, with a bulkier sewing cuff, after more aggressive annular debridement. Although initially there was no paravalvular leak, it recurred five days later. The patient also developed a small cerebral hemorrhage. As the paravalvular leak and hemolytic anemia gradually worsened, the patient underwent reoperation 14 days later. A Carpentier-Edwards
Investigation of Mitral Valve Replacement in a Patient with Mitral Valve Stenosis Who Complicated with Myelodysplastic Syndrome...Investigation of Mitral Valve Replacement in a Patient with Mitral Valve Stenosis Who Complicated with Myelodysplastic Syndrome...
Patients with myelodysplastic syndrome (MDS) most commonly have refractory anemia accompanied by various degrees of granulocytopenia and thrombocytopenia. At the time of cardiac surgery, both major infections and bleeding are severe complications in patients with pancytopenia due to MDS. However, there were very few patients with MDS who had undergone open-heart surgery. We reported a case of mitral valve replacement in a patient with MDS. A 68-year-old man with valvular heart disease and MDS, with a platelet count of 1.9 ~104/mm3, underwent successful mitral valve replacement. The mitral valve was replaced by an SJM25A prosthesis after resection of left atrial thrombosis using cardiopulmonary bypass. Platelets were transfused after the bypass. Perioperative hemorrhage was moderate and postoperative course was uneventful. We evaluated platelet function by Sonoclot coagulation and a platelet function analyzer. We did not need a large amount of transfusion of red blood cells and platelets, and ...
The extent of papillary muscle approximation affects mortality and durability of mitral valve repair for ischemic mitral...The extent of papillary muscle approximation affects mortality and durability of mitral valve repair for ischemic mitral...
Since reduction annuloplasty alone for ischemic mitral regurgitation (MR) cannot prevent late recurrence of MR or improve survival for those with left ventricular (LV) dysfunction, and the surgical approach to this etiology is still controversial, we conducted a study to assess the efficacy of the additional papillary muscle approximation (PMA) procedure for ischemic MR by comparing the different subtypes of PMA. We studied 45 patients who underwent mitral annuloplasty and papillary muscle approximation (PMA) for ischemic MR between 2003 and 2012. Papillary muscles were approximated entirely (cPMA: complete PMA, n = 32) through an LV incision or partially from the tips to mid-parts (iPMA: incomplete PMA, n = 13) through the mitral and aortic valves. Twenty-three patients with cPMA also underwent LV plasty (LVP). We assessed the outcomes after PMA by comparing cPMA and iPMA. The baseline MR grade, NYHA class, LV end-diastolic diameter, and LV ejection fraction (LVEF) were 2.8 ± 1.0, 3.2 ± 0.6, 67 ± 6
Feasibility and predictors of early discharge after percutaneous edge-to-edge mitral valve repair | HeartFeasibility and predictors of early discharge after percutaneous edge-to-edge mitral valve repair | Heart
Methods and results Consecutive patients treated with MitraClip from October 2008 to December 2015 were analysed. Primary outcomes of interest were cardiovascular and non-cardiovascular mortality, rehospitalisation for heart failure and major adverse events at 30 days and 90 days. A total of 269 patients were included. Of these, 115 patients were early discharged (ED group). Rates of ED increased from 25.9% for the biennium 2008-2009 to 59.1% in 2014-2015 (p,0.001 for trend). In a penalised logistic regression model, male gender (OR=2.13, 95% CI 1.17 to 3.95) and procedural year (OR=2.13, 95% CI 1.51 to 3.11) were associated with higher probability of ED. Conversely, atrial fibrillation (OR=0.48, 95% CI 0.27 to 0.85), any Mitral Valve Academic Research Consortium bleeding (OR=0.07, 95% CI 0.01 to 0.60), log-transformed N-terminal pro-brain natriuretic peptide levels (OR=0.79, 95% CI 0.63 to 0.99) and postimplant MR grade (OR=0.60, 95% CI 0.37 to 0.94) conferred a lower likelihood of ED. In ...
Transesophageal echocardiography-guided percutaneous intervention for a mitral valve leaflet perforation<...Transesophageal echocardiography-guided percutaneous intervention for a mitral valve leaflet perforation<...
TY - JOUR. T1 - Transesophageal echocardiography-guided percutaneous intervention for a mitral valve leaflet perforation. AU - Goswami, Rajiv. AU - Colin, Barker. AU - Jackson, Matthew. AU - Kleiman, Neal. AU - Little, Stephen. PY - 2015/4/27. Y1 - 2015/4/27. KW - duct occluder. KW - intervention. KW - mitral valve. KW - regurgitation. UR - http://www.scopus.com/inward/record.url?scp=84929190266&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=84929190266&partnerID=8YFLogxK. U2 - 10.1016/j.jcin.2014.11.028. DO - 10.1016/j.jcin.2014.11.028. M3 - Article. C2 - 25946451. AN - SCOPUS:84929190266. VL - 8. SP - 754. EP - 755. JO - JACC: Cardiovascular Interventions. JF - JACC: Cardiovascular Interventions. SN - 1936-8798. IS - 5. ER - ...
Mitral Valve Replacement: Minimally InvasiveMitral Valve Replacement: Minimally Invasive
A minimally invasive mitral valve replacement is a procedure to replace a poorly working mitral valve with an artificial valve. The mitral valve helps blood flow through the heart and out to the body. Your doctor will use an artificial valve to replace your poorly working mitral valve.
Finite Element Modeling of Mitral Valve Repair | Journal of Biomechanical Engineering | ASME DCFinite Element Modeling of Mitral Valve Repair | Journal of Biomechanical Engineering | ASME DC
The mitral valve is a complex structure regulating forward flow of blood between the left atrium and left ventricle (LV). Multiple disease processes can affect its proper function, and when these diseases cause severe mitral regurgitation (MR), optimal treatment is repair of the native valve. The mitral valve (MV) is a dynamic structure with multiple components that have complex interactions. Computational modeling through finite element (FE) analysis is a valuable tool to delineate the biomechanical properties of the mitral valve and understand its diseases and their repairs. In this review, we present an overview of relevant mitral valve diseases, and describe the evolution of FE models of surgical valve repair techniques.. ...
Mitral Valve RegurgitationMitral Valve Regurgitation
The heart has four valves that regulate blood flow through the heart. The mitral valve is the heart valve located between the left atrium, or upper chamber of the heart, and left ventricle, or lower chamber of the heart. After the left atrium fills with blood the mitral valve opens to allow the blood to flow down into the left ventricle. When the heart pumps and the left ventricle contracts, the mitral valve closes and blood flows outward through the aortic valve (the exit valve of the heart) and into the circulation of the body.. If the mitral valve does not close properly, blood flows backwards into the left atrium. This back flow is called "regurgitation." Small amounts of regurgitation are well tolerated, but if the amount increases over time, symptoms such as breathlessness and weakness can result. The heart muscle grows larger due to increased work load and becomes a less efficient pump.. Medicines or heart valve surgery may be recommended as treatment.. ...
Recurrence of mitral valve regurgitation after mitral valve repair in degenerative valve disease. | DIAL.pr - BOREALRecurrence of mitral valve regurgitation after mitral valve repair in degenerative valve disease. | DIAL.pr - BOREAL
Poncelet, Alain. Recurrence of mitral valve regurgitation after mitral valve repair in degenerative valve disease.. In: Circulation, Vol. 108, no.17, p. 125e-125 (2003 ...
Comparison of clinical outcomes in patients undergoing mitral valve replacement with mechanical or biological substitutes: a 20...Comparison of clinical outcomes in patients undergoing mitral valve replacement with mechanical or biological substitutes: a 20...
The choice of prosthesis for mitral valve replacement still remains controversial. This study assessed mortality, bleeding events and reoperation in patients who underwent mitral valve replacement surgery with biological or mechanical substitutes. A total of 352 patients who underwent mitral valve replacement surgery between 1990 and 2008 with 5 to 23 years of follow-up were retrospectively evaluated in a cohort study. The 5, 10, 15 and 20 year survival rates after surgery using a mechanical substitute were 87.7%, 74.2%, 69.3% and 69.3%, respectively, while after surgery with a biological substitute, they were 87.6%, 71.0%, 64.2% and 56.6%, respectively. There was no significant difference between the two groups (p = 0.38). In the multivariate analysis, the factors associated with death were age, bleeding events and renal failure. The probabilities of remaining free of reoperation at 5, 10, 15 and 20 years after surgery using a mechanical substitute were 94.4%, 92.7%, 92.7% and 92.7%; after surgery with
Mechanisms of hemolysis after mitral valve repair: assessment by serial echocardiography | JACC: Journal of the American...Mechanisms of hemolysis after mitral valve repair: assessment by serial echocardiography | JACC: Journal of the American...
In vitro studies have demonstrated that shear forces ,3000 dynes/cm2are associated with significant red cell destruction (24). A recent report by Garcia et al. provided new insights into the pathophysiology of mitral prosthetic hemolysis (8). Using fluid dynamic simulation models, they showed that rapid acceleration, fragmentation and collision jets were associated with high shear stress and may therefore produce hemolysis, whereas free and slow deceleration jets were not. However, their study included only 3 patients with hemolytic anemia after mitral valve repair.. This study was therefore conducted to determine the hydrodynamic mechanisms involved in the occurrence of hemolysis after mitral valve repair as assessed by serial two-dimensional and color flow Doppler echocardiography. We found that clinically significant hemolysis in patients after mitral valve repair is associated with distinct patterns of regurgitant flow that have been shown (8)to be associated with high shear stress: ...
Percutaneous Mitral Valve Repair Periprocedural Care: Preprocedural Planning, EquipmentPercutaneous Mitral Valve Repair Periprocedural Care: Preprocedural Planning, Equipment
Percutaneous mitral valve repair (MVR) is used to treat mitral regurgitation (MR; depicted in the image below). Percutaneous procedures used to treat valvular heart disease were first developed decades ago; the first pulmonic balloon valvuloplasty was reported in 1982 and was quickly followed by applications to the aortic and mitral valves.
Sabinet | Mitral valve and coronary artery bypass surgeries 13 years after pneumonectomy for lung cancer : online article -...Sabinet | Mitral valve and coronary artery bypass surgeries 13 years after pneumonectomy for lung cancer : online article -...
We successfully performed coronary artery bypass grafting and mitral valve replacement in a 72-year-old man who had undergone a left pneumonectomy 13 years previously due to a malignant mass. The patient was admitted to our clinic with symptoms of dyspnoea, palpitations, chest pain and fatigue. He was diagnosed with mitral valve disease and two-vessel coronary artery disease, as seen from echocardiography and catheterisation studies. Conventional cardiopulmonary bypass grafting was performed following sternotomy. The patient's heart was completely displaced to the left hemithorax. Saphenous vein grafts were harvested. Distal anastomoses were performed with the use of the on-pump beating heart technique without cross clamping. Afterwards a cross clamping was placed and a left atriotomy was performed. The mitral valve was severely calcific. A mitral valve replacement was performed using number 27 mechanical valve after the valve had been excised. The patient's postoperative course was uneventful
Impact of Complications on Outcomes Following Aortic and Mitral Valve Replacements in the United States - RedorbitImpact of Complications on Outcomes Following Aortic and Mitral Valve Replacements in the United States - Redorbit
By Allareddy, V Ward, M M; Ely, J W; Allareddy, V; Levett, J Aim. Heart valve replacement surgeries account for 20% of all cardiac procedures. In-hospital mortality rates are approximately 6% for aortic valve replacements and 10% for mitral valve replacements. The objectives of the study are to provide nationally representative estimates of complications following aortic and mitral valve replacements and to quantify the impact of different types of complications on in-hospital outcomes. Methods. The Nationwide Inpatient Sample was analyzed for years 2000-2003. The effect of complications on in-hospital mortality, length of stay (LOS), and hospital charges were examined using bivariate and multivariable logistic and linear regression analyses. The confounding effects of age, sex, primary diagnosis, type of valve replacement, type of admission, comorbid conditions, and hospital characteristics were adjusted. Results. A total of 43 909 patients underwent aortic valve replacement as the primary ...
Reference Center Referrals : Mitral Valve Repair Reference CenterReference Center Referrals : Mitral Valve Repair Reference Center
The Mitral Valve Repair Reference Center at Mount Sinai now offers patients the highest percentages of mitral valve repair anywhere in the world., Refer a patient to the mitral valve repair program at The Mount Sinai Hospital.
Leaflets : Mitral Valve Repair Reference CenterLeaflets : Mitral Valve Repair Reference Center
The Mitral Valve Repair Reference Center at Mount Sinai now offers patients the highest percentages of mitral valve repair anywhere in the world., The mitral valve has two leaflets, the antierior leaflet and the posterior leaflet.
Myxomatous Mitral Valve Disease in Dogs - an Update and Perspectives : Macedonian Veterinary ReviewMyxomatous Mitral Valve Disease in Dogs - an Update and Perspectives : Macedonian Veterinary Review
22. Reynolds, C.A., Brown, D.C., Rush, J.E., Fox, P.R., Nguyenba, T.P., Lehmkuhl, L.B., Gordon, S.G., Kellihan, H.B., Stepien, R.L, Lefbom, B.K., Meier, C.K.,Oyama, M.A. (2012). Prediction of first onset of congestive heart failure in dogs with degenerative mitral valve disease: The PREDICT cohort study. J. Vet. Cardiol. 14, 1, 193-202. http://dx.doi.org/10.1016/j.jvc.2012.01.008CrossrefGoogle Scholar ...
Echocardiographic assessment of left ventricular filling after mitral valve surgery. | HeartEchocardiographic assessment of left ventricular filling after mitral valve surgery. | Heart
In order to investigate the functional effects of mitral valve surgery, echocardiograms showing left ventricular dimension were recorded and digitised in 14 normal subjects and 129 patients after mitral valve surgery. Measurements were made of peak rate of increase of dimension (dD/dt) and duration of rapid filling, studies on left ventriculograms in 36 patients having shown close correlation between these values and changes in cavity volume. In 14 patients with mitral stenosis, peak dD/dt was reduced to 7-2 +/ 1-5 cm/s, and filling period prolonged to 330 +/- 65 ms, compared with normal (16-0 +/- 3-2 cm/s, and 160 +/- 50 ms, respectively), and after mitral valvotomy, these values improved significantly (10-4 +/- 2-7 cm/s and 245 +/- 55 ms). Characteristic abnormalities were found in 67 patients with mitral prostheses. Values for the Björk-Shiley (10-5 +/- 4-2 cm/s and 180 +/- 80 ms) and Hancock (10-3 +/- 3-7 cm/s, 245 +/- 80 ms) values were similar, and both superior to the Starr-Edwards (7-4 ...
Multicenter evaluation of high-risk mitral valve operations: Implications for novel transcatheter valve therapies<...Multicenter evaluation of high-risk mitral valve operations: Implications for novel transcatheter valve therapies<...
TY - JOUR. T1 - Multicenter evaluation of high-risk mitral valve operations. T2 - Implications for novel transcatheter valve therapies. AU - Lapar, Damien J.. AU - Isbell, James M.. AU - Crosby, Ivan K.. AU - Kern, John. AU - Lim, D. Scott. AU - Fonner, Edwin. AU - Speir, Alan M.. AU - Rich, Jeffrey B.. AU - Kron, Irving L.. AU - Ailawadi, Gorav. PY - 2014/12/1. Y1 - 2014/12/1. N2 - Results Of 2,440 isolated mitral operations, 29% (n = 698) were HR per REALISM criteria. Median STS Predicted Risk of Mortality (PROM) for HR patients was 6.6% compared with 1.6% for non-HR patients (p , 0.001). The HR patients more commonly underwent MV replacement as well as urgent (30% vs 19%, p , 0.001) operations. High-risk patients incurred higher morbidity and mortality (7% vs 1.6%) with longer intensive care unit (48 vs 41 hours) and hospital stays (7 vs 6 days, all p , 0.001). Among REALISM criteria, STS PROM 12% or greater and high-risk STS criteria were the only criteria associated with ...
BestBets: Is short-term anticoagulation necessary after mitral valve repair?BestBets: Is short-term anticoagulation necessary after mitral valve repair?
The ACC/AHA 1998 guidelines for the management of patients with valvular heart disease do not provide recommendations for patients who have undergone a mitral valve repair and neither do the ACCP guidelines of 2004. The European Society of Cardiology do provide guidelines for these patients, stating that there are no randomized controlled trials to support the safety of omitting warfarin after mitral repair. They recommend 3 months of warfarin at a target INR of 2.5 or 3.0 if there are additional risk factors. They acknowledge that this is based on expert consensus and acknowledge that many surgeons do not follow this guideline. Vaughan et al in a survey of UK surgeons found that 64% of consultants used warfarin post mitral repair, thus demonstrating that there is much variation in the anticoagulation management of patients post mitral repair in the UK. Of the large series of patients with mitral valve repair, Carpentier et al have provided the longest follow up. They reported their long term ...
Bioprosthetic vs. Mechanical Mitral Valve Replacement in Patients Aged 50-69 Years | Journal Scan - American College of...Bioprosthetic vs. Mechanical Mitral Valve Replacement in Patients Aged 50-69 Years | Journal Scan - American College of...
No survival difference was observed between use of mechanical and bioprosthetic mitral valves in patients aged 50-69 years matched by propensity score (actuarial 15-year survival 57.5% [95% confidence interval (CI) 50.5-64.4%] vs. 59.9% [95% CI 54.8-65.0%], hazard ratio [HR] 0.95 [95% CI 0.79-1.15]), or in a subgroup analysis of age by decade. Among patients matched by propensity score, mechanical versus bioprosthetic mitral valve replacement was associated with higher 15-year incidence of stroke (14.0% [95% CI 9.5-18.6%] vs. 6.8% [95% CI 4.5-8.8%], HR 1.62 [95% CI 1.10-2.39]) and bleeding events (14.9% [95% CI 11.0-18.8%] vs. 9.0% [95% CI 6.4-11.5%], HR 1.50 [95% CI 1.05-2.16]), but a lower incidence of reoperation (5.0% [95% CI 3.1-6.9%] vs. 11.1% [95% CI 7.6-14.6%], HR 0.59 [95% CI 0.37-0.94]).. ...
Patent US7186264 - Method and apparatus for improving mitral valve function - Google PatentsPatent US7186264 - Method and apparatus for improving mitral valve function - Google Patents
A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.
Mitral valve leaflets | definition of Mitral valve leaflets by Medical dictionaryMitral valve leaflets | definition of Mitral valve leaflets by Medical dictionary
Looking for online definition of Mitral valve leaflets in the Medical Dictionary? Mitral valve leaflets explanation free. What is Mitral valve leaflets? Meaning of Mitral valve leaflets medical term. What does Mitral valve leaflets mean?
The Auscultation Assistant - Mitral Valve ProlapseThe Auscultation Assistant - Mitral Valve Prolapse
Systolic Murmurs - Mitral Valve Prolapse. You are listening to a typical example of the murmur caused by mitral valve prolapse. The pathophysiology of mitral valve prolapse is varied, but can be thought of as an inability of the papillary muscles or chordae tendineae to completely tether the mitral valve during the late stages of systole. As the left ventricle chamber decreases in size, the papillary muscles and/or the chordae fail to maintain tension on the mitral valve, and it prolapses with a brief regurgitant period into the left atrium. This is a common syndrome which frequently is associated with young adult women, and can present as attacks of palpitations, anxiety, or light-headedness. Although it is usually a mild symptom, patients with mitral valve prolapse with evidence of regurgitation by echo should be given antibiotic prophylaxis during invasive procedures to help prevent bacterial endocarditis.. The murmur of mitral valve prolapse is somewhat complex. Following a normal S1 and ...
Mitral valve repair - WikipediaMitral valve repair - Wikipedia
In 1923 Dr. Elliott Cutler of the Peter Bent Brigham Hospital performed the worlds first successful heart valve surgery - a mitral valve repair. The patient was a 12-year-old girl with rheumatic mitral stenosis.. The development of the heart-lung machine in the 1950s paved the way for replacement of the mitral valve with an artificial valve in the 1960s. For decades after, mitral valve replacement was the only surgical option for patients with a severely diseased mitral valve. However, there are some significant downsides to a prosthetic mitral valve. Infection of the valve can occur, which is dangerous and difficult to treat. Patients with mechanical heart valves are required to take blood thinners for the rest of their lives, which presents a risk of bleeding complications. The artificial mitral valve has an elevated risk of stroke. Patients with mechanical heart valves who use warfarin for anticoagulation have to be on long-term anticoagulation therapy. This means they must go to the clinic ...
Mitral Valve Stenosis And Mitral Valve Replacement Support Group | Heart, Blood and Circulatory SystemMitral Valve Stenosis And Mitral Valve Replacement Support Group | Heart, Blood and Circulatory System
Heart, Blood and Circulatory System - Mitral Valve Stenosis And Mitral Valve Replacement Support Group - Rheumatic fever is still the main cause of mitral valve disease in India. Mitral valve replacement is recommended in patients with moderate to severe mitral regurgitation
Coronary Atherosclerosis & Mitral Valve Insufficiency & Thickening of the Mitral Valve Leaflets: Causes & Reasons - SymptomaCoronary Atherosclerosis & Mitral Valve Insufficiency & Thickening of the Mitral Valve Leaflets: Causes & Reasons - Symptoma
Coronary Atherosclerosis & Mitral Valve Insufficiency & Thickening of the Mitral Valve Leaflets Symptom Checker: Possible causes include Mitral Valve Prolapse. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Dog Mitral Valve Insufficiency (MVI) Iowa City IA - Dog Mitral Valve Insufficiency (MVI), Iowa City IA dog adoption, Iowa City...Dog Mitral Valve Insufficiency (MVI) Iowa City IA - Dog Mitral Valve Insufficiency (MVI), Iowa City IA dog adoption, Iowa City...
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Alfieri stitch for temporary severe functional mitral regurgitation after aortic valve replacement | Surgical Case Reports |...Alfieri stitch for temporary severe functional mitral regurgitation after aortic valve replacement | Surgical Case Reports |...
The outcome in functional mitral regurgitation after aortic valve replacement is unclear. A frail 82-year-old woman with severe aortic valve regurgitation and mild to moderate functional mitral valve regurgitation (NYHA functional class III) was referred to our clinic. In consideration of her frail condition, aortic valve replacement without mitral surgery was performed. She had hemodynamic instability and difficulty to wean off cardiopulmonary bypass caused by severe functional mitral valve regurgitation with left ventricular dilatation. A central Alfieri edge-to-edge stitch was placed between the anatomical middle of the two leaflets of the mitral valve after reinstitution of cardiopulmonary bypass. This eliminated the mitral regurgitation, which enabled successful separation from cardiopulmonary bypass.
Localizing Mitral Valve Perforations With 3D Transesophageal Echocardiography | JACC: Cardiovascular ImagingLocalizing Mitral Valve Perforations With 3D Transesophageal Echocardiography | JACC: Cardiovascular Imaging
with the advent of real-time 3-dimensional transesophageal echocardiography (3d tee), rapid creation of high-quality, true-to-life images of mitral valve anatomy and pathology has become possible in the vast majority of patients (1). In addition to common mitral valve lesions, such as degenerative mitral valve disease, 3D TEE is invaluable for characterizing less frequently encountered disorders, including endocarditis and its complications (2). Precise localization of leaflet perforations can be challenging on 2-dimensional images, particularly for non-experts. While the affected scallop can often be identified with the help of color Doppler, it may be difficult to pinpoint the site of perforation with respect to the leaflet tip. The addition of 3D TEE often provides clarity in this regard, helping to determine the feasibility of surgical repair. In this iPIX, we demonstrate the role of real-time 3D TEE in characterizing mitral leaflet perforations at various sites. Asterisks denote the aorta ...
Dyspnea & Mitral Valve Prolapse & Thickening of the Mitral Valve Leaflets: Causes & Reasons - SymptomaDyspnea & Mitral Valve Prolapse & Thickening of the Mitral Valve Leaflets: Causes & Reasons - Symptoma
Dyspnea & Mitral Valve Prolapse & Thickening of the Mitral Valve Leaflets Symptom Checker: Possible causes include Mitral Valve Prolapse. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Mitral valve prolapse - WikipediaMitral valve prolapse - Wikipedia
Mitral valve prolapse (MVP; a.k.a. floppy mitral valve syndrome, systolic click murmur syndrome or billowing mitral leaflet) is a valvular heart disease characterized by the displacement of an abnormally thickened mitral valve leaflet into the left atrium during systole. It is the primary form of myxomatous degeneration of the valve. There are various types of MVP, broadly classified as classic and nonclassic. In its nonclassic form, MVP carries a low risk of complications and often can be kept minimal by dietary attention. In severe cases of classic MVP, complications include mitral regurgitation, infective endocarditis, congestive heart failure, and, in rare circumstances, cardiac arrest. The diagnosis of MVP depends upon echocardiography, which uses ultrasound to visualize the mitral valve. The prevalence of MVP is estimated at 2-3% of the population. The condition was first described by John Brereton Barlow in 1966. In consequence, it may also be referred to as Barlows syndrome, and was ...
Mitral Valve Insufficiency | IVG HospitalsMitral Valve Insufficiency | IVG Hospitals
Mitral valve insufficiency (MI) is inadequate closure of the valve that separates the left atrium from the left ventricle. This disorder can be due to backward movement of the valve (prolapsing), thickening of the valve, gradual (chronic) degeneration of the valve, bacterial infection of the valve, narrowing of the opening in the valve or dysfunction of the muscles or chords controlling the valve. Chronic degeneration of the valve is the most common cause of MI in dogs and cats.. This inability to close the mitral valve completely causes regurgitation (backward flow) of blood into the left atrium of the heart. This regurgitation increases the amount of blood that the left atrium has to pump, which may lead to volume overloading. As a means of compensation, the left atrium may dilate (expand). This is a condition known as left atrial enlargement. In later stages of disease, the left ventricle and veins of the lungs are generally enlarged as well.. Signs of MI include coughing, increased heart ...
Unusual findings in secondary hypertension: double orifice mitral associated to aortic coarctation, bicuspid aortic valve, and...Unusual findings in secondary hypertension: double orifice mitral associated to aortic coarctation, bicuspid aortic valve, and...
Double orifice mitral valve is a rare congenital anomaly presenting as the division of the mitral orifice into two anatomically distinct orifices, it is most often associated with other congenital heart defects such as left-sided obstructive lesions, ventricular septal defects or aortic coarctation. We report the case of a 15 years old boy, admitted for arterial hypertension, auscultation revealed a rude aortic systolic murmur. Femoral pulses were weak. Owing to the suspicion of aortic coarctation, transthoracic echocardiography was performed, the aortic coarctation with dilation of the aorta proximal to the stenosis was confirmed and bicuspid aortic valve was found with good function. The mitral valve was dysmorphic, having two orifices; it was divided into 2 separate valve orifices by a fibrous bridge. No mitral or aortic regurgitation was documented by color Doppler flow imaging. The left ventricular ejection fraction was normal. There was a small peri membranous ventricular septal defect with left
Mitral Valve Regurgitation: Repair or Replace the Valve? - North Kansas City Hospital, Kansas City, MOMitral Valve Regurgitation: Repair or Replace the Valve? - North Kansas City Hospital, Kansas City, MO
To treat mitral valve regurgitation surgically, the options are to repair or replace the mitral valve. Repair of the heart valve may be recommended if it is likely that the valve can be repaired and that the repair will last a long time.. Valve replacement may be recommended if your mitral valve is seriously damaged and cannot be repaired.. The decision about whether to repair or replace a valve is based on many things, including your general health, the condition of the damaged valve, the presence of other health conditions, and the expected benefits of surgery. In some cases, the decision clearly may be in favor of repair or in favor of replacement.. ...
HealthDay - Mitral Valve ProlapseHealthDay - Mitral Valve Prolapse
Mitral valve prolapse is a condition that occurs when the mitral valve of the heart doesnt work properly. This valve controls the flow of blood between the upper left chamber of the heart (the left atrium) and the lower left chamber (the left ventricle). Normally, the mitral valve forms a tight seal between the two when it needs to. But with mitral valve prolapse, the valve doesnt seal tightly, which can cause blood to flow back in the opposite direction. This in turn can cause a variety of heart complications.
Cardiosurgery: Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Treatment...Cardiosurgery: Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Treatment...
Cardiosurgery: Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Treatment in Tuebingen, Germany ✈ Find the best medical programs at BookingHealth - ✔Compare the prices ✔Online booking.
Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Cardiosurgery: Treatment...Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Cardiosurgery: Treatment...
Mitral valve insufficiency (prolapse) | Prosthetic (replacement) of mitral valve (minimally invasive). Cardiosurgery: Treatment abroad ✈. Clinics on BookingHealth.com - booking treatment online!
Members | Mitral Valve Stenosis And Mitral Valve Replacement Support Group | Heart, Blood and Circulatory SystemMembers | Mitral Valve Stenosis And Mitral Valve Replacement Support Group | Heart, Blood and Circulatory System
Members of Mitral Valve Stenosis And Mitral Valve Replacement Support Group - Heart, Blood and Circulatory System. Discuss with people facing similar health challenges as yours. Seek advice from our online experts.
Propensity-matched analysis of outcomes after mitral valve surgery between trainees and consultants (institutional report)<...Propensity-matched analysis of outcomes after mitral valve surgery between trainees and consultants (institutional report)<...
TY - JOUR. T1 - Propensity-matched analysis of outcomes after mitral valve surgery between trainees and consultants (institutional report). AU - Bruno, Vito D.. AU - Chivasso, Pierpaolo. AU - Hayat, Amna. AU - Marsico, Roberto. AU - Benedetto, Umberto. AU - Caputo, Massimo. AU - Ascione, Raimondo. AU - Angelini, Gianni D.. AU - Ciulli, Franco. AU - Vohra, Hunaid A.. PY - 2018/3/1. Y1 - 2018/3/1. N2 - OBJECTIVES: We aimed to determine whether early outcomes and long-term survival after mitral valve surgery performed by trainee residents are equivalent in terms of safety and efficacy when compared with consultant surgeons. METHODS: Between January 2000 and December 2015, a total of 1742 patients who underwent mitral valve surgery were identified. Of these, 1622 operations were performed by consultants (Group I) and 120 operations were performed by trainees (Group II). A propensity score-matched analysis has been used to minimize selection bias. Early postoperative outcomes were defined as ...
Initial Experience of Transcatheter Mitral Valve Replacement - American College of CardiologyInitial Experience of Transcatheter Mitral Valve Replacement - American College of Cardiology
Unlike reported cases in which a transcatheter aortic valve device was implanted in the mitral position in the setting of dense annular calcification or a degenerated bioprosthesis, it might be feasible to use the FORTIS device in the setting of primary or secondary noncalcific MR. This first report of three patients with 6-month follow-up after transcatheter mitral valve replacement is encouraging, yet it might be premature to draw firm conclusions about procedural complication rates and clinical outcomes from this very small single-center experience. If positive results are borne out in a larger, multicenter trial or trials, then transcatheter mitral valve replacement with this or another device might provide an attractive alternative to the limited MR reduction afforded by transcatheter edge-to-edge repair.. ...
Radiofrequency pulmonary veins isolation of atrial fibrillation in patients undergoing mitral valve replacement - Open Medicine...Radiofrequency pulmonary veins isolation of atrial fibrillation in patients undergoing mitral valve replacement - Open Medicine...
Introduction: Pulmonary veins isolation (PVI) is useful method in patients (pts) with mitral valve disease (MVD) and chronic atrial fibrillation (AF) during prosthetic valve implantation. The aim of the study: To evaluate e.ectiveness of PVI in the treatment of AF in pt with MVD during valve implantation. Material and methods: 45 pts (mean age 55 yrs) with AF were operated on for MVD.RF ablation around the pulmonary veins, a lesion between them and to the mitral annulus were performed. There were 44 prostheses implanted, 1 case of mitral valve annuloplasty, associated with tricuspid valve repair (5 pts), aorto-coronary bypass procedure (2 pts), ASD II closure (1 pt). Results: SR was achieved in 2 (44,5%) pts, 21 (46,5%)pts were in AF, 4 (9%) pts needed pacing. No correlation between SR restoration and preoperative echocardiographic parameters, age, gender, NYHA functional class were found. In long-term follow-up 1 pt have reversed AF to SR spontaneously. There were 6 cases of paroxysmal AF,1 pt ...
What You Should Know About Mitral Valve Prolapse - American Family PhysicianWhat You Should Know About Mitral Valve Prolapse - American Family Physician
Most people with mitral valve prolapse dont need any treatment. In fact, this condition usually has no effect on your health. About two of every 100 people with this condition have complications. You may need surgery to fix the valve if your valve is too leaky or if you are having lots of symptoms. You may also have to limit your participation in competitive sports. Ask your doctor if you are in this group.. If your mitral valve prolapse causes chest pains or other symptoms, your doctor might prescribe medicines such as beta blockers to make your symptoms better.. Some people get an infection in the leaky valve when they have surgery or dental work. You might take antibiotics before surgery or dental work to prevent this infection. Remind your dentists and doctors that you have mitral valve prolapse so that you can get a prescription for antibiotics when you are going to have surgery or dental work. ...
The impact of intraoperative residual mild regurgitation after repair of degenerative mitral regurgitation<...The impact of intraoperative residual mild regurgitation after repair of degenerative mitral regurgitation<...
TY - JOUR. T1 - The impact of intraoperative residual mild regurgitation after repair of degenerative mitral regurgitation. AU - Imielski, Bartlomiej. AU - Malaisrie, S. Chris. AU - Pham, Duc Thinh. AU - Kruse, Jane. AU - Andrei, Adin Cristian. AU - Liu, Menghan. AU - Cox, James L.. AU - McCarthy, Patrick M.. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Objectives: During degenerative mitral repair, surgeons must decide if further repair is warranted for residual mild mitral regurgitation. We examined the incidence of mild mitral regurgitation, late echocardiographic and clinical outcomes, and influence of surgical experience in decision making. Methods: From April 2004 to June 2018, 1155 of 1195 patients with pure degenerative disease underwent repair (97% repair rate). Propensity score matching was performed between patients with trace/no mitral regurgitation and patients with mild residual mitral regurgitation. Late echocardiographic outcome and freedom from reoperation were compared using ...
Systolic anterior motion (SAM) of the mitral valve | Radiology Reference Article | Radiopaedia.orgSystolic anterior motion (SAM) of the mitral valve | Radiology Reference Article | Radiopaedia.org
Systolic anterior motion (SAM) of the mitral valve is defined as displacement of the distal portion of the anterior leaflet of the mitral valve toward the left ventricular outflow tract obstruction. It can occur in patients with and without hyper...
Best Mitral Valve Stenosis Doctor in Navi Mumbai, Mitral Valve Stenosis Doctors | CredihealthBest Mitral Valve Stenosis Doctor in Navi Mumbai, Mitral Valve Stenosis Doctors | Credihealth
Find the best mitral valve stenosis doctors in Navi Mumbai. Get guidance from medical experts to select mitral valve stenosis specialist in Navi Mumbai from trusted hospitals - credihealth.com
Mitral Valve ProlapseMitral Valve Prolapse
... (also known as systolic click murmur syndrome, billowing mitral leaflet or floppy mitral valve syndrome) is the valvular heart disease characterized by the abnormal displacement of thickened mitral valve leaflet into the left atrium during systole, and it is the primary form of the myxomatous degeneration of the valve. This is the forum for discussing anything related to this health condition
Most recent papers with the keyword Transcatheter mitral valve repair | Read by QxMDMost recent papers with the keyword Transcatheter mitral valve repair | Read by QxMD
The left ventricular apex has excellent accessibility to the aortic valve, mitral valve, left ventricular outflow tract and thoracic aorta. Although the number of transapical approach in transcatheter aortic valve replacement has been decreasing in recent years, it is still a useful option for patients with very poor peripheral vascular access. The apex has been chosen as a primary access site for many devices of transcatheter mitral valve repair/replacement and mitral valve-in-valve procedures. Additionally, the transapical approach has been used for other transcatheter cardiovascular interventions such as paravalvular leak repair after mitral or aortic valve replacement, pseudoaneurysm repair of the left ventricular outflow tract, and thoracic endovascular aortic repair ...
Lirias: Aortic and mitral valve replacement with the Carpentier-Edwards pericardial bioprosthesis: mid-term clinical resultsLirias: Aortic and mitral valve replacement with the Carpentier-Edwards pericardial bioprosthesis: mid-term clinical results
Between May 1st 1985 and December 31st 1992, 283 Carpentier-Edwards pericardial valves were implanted in 260 patients in the aortic (n = 196), mitral (n = 41) and both aortic and mitral (n = 23) positions at the Gasthuisberg University Hospital in Leuven, Belgium. Patients undergoing tricuspid valve replacement or mixed replacement with another type of prosthesis were excluded from this study. The mean age was 70 +/- 7 years, there were 121 males and 139 females. The mean follow up was 40.55 months, the total follow up experience 10543 months (878.6 patients years). Hospital mortality was 10.4%, and was not significantly related to the position of the valve: 17.3% +/- 7.88% (n = 23) for double valve replacement, 10.2% +/- 2.16% (n = 196) for aortic valve replacement and 7.3% +/- 4.06% (n = 41) for mitral valve replacement. Hospital mortality was 14.1% +/- 3.27% for those with and 7.48% +/- 2.5% for those without concomitant coronary surgery (p = NS). Survival at 92 months was 63% +/- 6% and was ...
Anesthetic management of a patient with moyamoya disease undergoing mitral valve repair<...Anesthetic management of a patient with moyamoya disease undergoing mitral valve repair<...
TY - JOUR. T1 - Anesthetic management of a patient with moyamoya disease undergoing mitral valve repair. AU - Ishikawa, Saki. AU - Yamada, Tatsuya. AU - Sakaguchi, Ryota. AU - Hatorl, Eiki. AU - Morisaki, Hiroshi. PY - 2014/3. Y1 - 2014/3. N2 - Moyamoya disease is the result of progressive steno-occlusive changes in the internal carotid arteries followed by formation of bilateral abnormal vascular networks. The disease may present with cerebral ischemia causing cerebral hemorrhage in the perioperative period. There are few reports of cardiac surgeries in patients with moyamoya disease, and the management during cardiopulmonary bypass for moyamoya disease has not been established We gave general anesthesia for mitral valve plasty in patient with the moyamoya disease. A 52-year-old woman underwent mitral valve plasty. She had been diagnosed with moyamoya disease and during the cardiopulmonary bypass, we used a-stat blood gas management with mild hypothermia and maintained Paco2 around 40 mmHg. We ...
Echocardiographic assessment of degenerative mitral stenosis: a diagnostic challenge of an Eemerging cardiac disease - UQ eSpaceEchocardiographic assessment of degenerative mitral stenosis: a diagnostic challenge of an Eemerging cardiac disease - UQ eSpace
Degenerative mitral stenosis (DMS) is characterized by decreased mitral valve (MV) orifice area and increased transmitral pressure gradient due to chronic noninflammatory degeneration and subsequent calcification of the fibrous mitral annulus and the MV leaflets. The "true" prevalence of DMS in the general population is unknown. DMS predominantly affects elderly individuals, many of whom have multiple other comorbidities. Transcatheter MV replacement techniques, although their long-term outcomes are yet to be tested, have been gaining popularity and may emerge as more effective and relatively safer treatment option for patients with DMS. Echocardiography is the primary imaging modality for evaluation of DMS and related hemodynamic abnormalities such as increased transmitral pressure gradient and pulmonary arterial pressure. Classic echocardiographic techniques used for evaluation of mitral stenosis (pressure half time, proximal isovelocity surface area, continuity equation, and MV area ...
Chapter 43. Surgical Treatment of Mitral Valve Endocarditis | Cardiac Surgery in the Adult, 4e | AccessSurgery | McGraw-Hill...Chapter 43. Surgical Treatment of Mitral Valve Endocarditis | Cardiac Surgery in the Adult, 4e | AccessSurgery | McGraw-Hill...
Native valve endocarditis (NVE) refers to infectious endocarditis involving a patients own (native) heart valve. Crude incidence of NVE is 6.2 per 100,000 people per year, and is highest in older age groups.5 The pathogenesis of NVE begins with endocardial trauma resulting in alteration of the valvular endocardial surface; this allows deposition of fibrin and platelets with subsequent attachment of bacteria. Endocardial injury may be secondary to rheumatic valvulitis or other leaflet disease, or valvular or annular calcification.5 Common reasons for bacteremia or fungemia predisposing to NVE include use of long-term indwelling catheters, intravenous drug abuse, and fungemia associated with prolonged antibiotic therapy.6,7 Although vegetations may be seen anywhere on the leaflets or the chordae, the usual site at which infective NVE of the mitral valve causes valvular destruction and invasion is at the base of the atrial aspect of the mitral valve leaflets. Annular or subannular invasion may ...
Diseases of the Mitral Valve | Texas Heart InstituteDiseases of the Mitral Valve | Texas Heart Institute
The mitral valve regulates the flow of blood from the upper-left chamber (the left atrium) to the lower-left chamber (the left ventricle). Three diseases of the mitral valve are mitral valve prolapse, mitral regurgitation, and mitral stenosis.
Patent US7632308 - Methods, devices, and kits for treating mitral valve prolapse - Google PatentsPatent US7632308 - Methods, devices, and kits for treating mitral valve prolapse - Google Patents
Described here are methods, devices, and kits for treating a prolapsed valve leaflet. The devices generally comprise a flexible cord, a first anchor attached to the cord at its distal end, and a second anchor slidably attached to the cord. The first anchor may be configured to secure the cord to cardiac tissue located below a prolapsed valve leaflet and the second anchor may be configured to secure into the prolapsed valve leaflet. Also described are methods for treating a prolapsed valve including the steps of securing a first anchor to cardiac tissue located below the prolapsed mitral valve leaflet, securing a second anchor to the prolapsed mitral valve leaflet, tensioning a cord connecting the two anchors and securing the cord. Kits including the described devices are also provided.
Concomitant mitral valve surgery in patients with moderate ischemic mitral regurgitation undergoing coronary artery bypass...Concomitant mitral valve surgery in patients with moderate ischemic mitral regurgitation undergoing coronary artery bypass...
Concomitant mitral valve surgery in patients with moderate ischemic mitral regurgitation undergoing coronary artery bypass grafting
Options for the Heart Valve Replacement - Friv4gamerOptions for the Heart Valve Replacement - Friv4gamer
Aortic valve and mitral valve are commonly replaced valves. The pulmonary and the tricuspid valve replacements also are uncommon among adults.. Replacing narrowed valve:. Most common valve procedure is the aortic valve replacement Singapore for the aortic stenosis, and narrowing of aortic valve. The mitral stenosis is one more condition that at times need valve replacement method.. Replacing leaky valve:. The aortic regurgitation, (at times referred as the aortic insufficiency) is one common valve problem, which might need valve replacement. The regurgitation means valve allows the blood to go back through valve and in heart rather than moving it ahead and out to your body. The aortic regurgitation will eventually lead to the heart failure.. ...
Anterolateral Right Thoracotomy for Mitral Valve Replacement for Treating Infectious Endocarditis in a Case with Esophagus...Anterolateral Right Thoracotomy for Mitral Valve Replacement for Treating Infectious Endocarditis in a Case with Esophagus...
A case of infectious endocarditis was surgically treated by mitral valve replacement. The patient had previously undergone presternal subcutaneous colonic interposition as reconstruction surgery due to esophageal and gastric cancer. This artificial esophagus prevented the central sternotomy that is necessary for cardiac surgery. In cases where sternotomy is difficult, anterolateral right intercostal thoracotomy is useful. Arterial cannulation was performed via the femoral artery; cannulations for venous drainage were performed in the femoral vein for the inferior vena cava and in the right jugular vein for the superior vena cava in order to establish cardiopulmonary bypass circulation. Under the condition of ventricular fibrillation and a body temperature of 25 , the mitral valve that had been destroyed by infection was resected by exposure of the left atrium on its right side. An artificial Saint Jude Medical mechanical valve, 29mm in diameter, was implanted. The thorax was insufflated with ...
A prospective controlled trial of St. Jude versus Starr Edwards aortic and mitral valve prostheses. - Semantic ScholarA prospective controlled trial of St. Jude versus Starr Edwards aortic and mitral valve prostheses. - Semantic Scholar
BACKGROUND There is a paucity of controlled trials comparing the merits of different heart valve prostheses. In this prospective randomized trial we compared Starr Edwards and St. Jude prostheses in the aortic and mitral positions. METHODS Two hundred sixty-seven patients and 122 patients undergoing aortic and mitral valve replacement, respectively, were allocated by minimization to receive either St. Jude or Starr Edwards prostheses. Patients (2 patients were lost to follow-up) were followed up in a special clinic. Event definition, recording, and reporting were in accordance with published guidelines. RESULTS There were no demographic differences between patients receiving the two different valve models. With the exception of infective endocarditis, we found no differences in the rates of death or complication between patients receiving a Starr Edwards prosthesis or a St. Jude prosthesis in either position. Neither were there any differences between the two valve models in either position, in
Valve SurgeryValve Surgery
Depending on the extent of your valve disease, you may need to have the valve repaired or replaced. To repair the valve, your surgeon may perform a commissurotomy or implant a valve ring. A commissurotomy is performed for a tight valve (stenosis). The valve leaflets are cut to loosen the valve slightly, allowing blood to pass easily. Another type of valve repair is a valve ring annuloplasty, which is sewn in place when the valve is leaking (regurgitant or insufficient). The valve leaflets are tucked in place with the ring.. Often the valve cannot be repaired and the surgeon must replace the damaged valve with a tissue (bioprosthetic) or mechanical valve. Tissue valve are valves from animals (e.g., cow, pig). They generally do not require long-term anticoagulation and are not as durable as mechanical valves. Mechanical valves are made from materials such as plastic or metal. They require long-term anticoagulation and are considered extremely durable, lasting longer than tissue valves.. Your ...
Beta blockerBeta blocker
Premature ventricular contractionPremature ventricular contraction
King Charles SpanielKing Charles Spaniel
Gerald M. LawrieGerald M. Lawrie
Victor SkuminVictor Skumin
Minimally invasive cardiac surgeryMinimally invasive cardiac surgery
Anorexia nervosaAnorexia nervosa
European Huntingtons Disease NetworkEuropean Huntington's Disease Network
BeaglierBeaglier
CT scanCT scan
ScurvyScurvy
Julie SwainJulie Swain
Cavalier King Charles SpanielCavalier King Charles Spaniel
Jean-Raymond BoulleJean-Raymond Boulle
Valsalva maneuverValsalva maneuver
Systolic heart murmurSystolic heart murmur
Nina Starr BraunwaldNina Starr Braunwald
Sphynx catSphynx cat
Cardiac myxomaCardiac myxoma
MASS syndromeMASS syndrome
Mushtak Al-AtabiMushtak Al-Atabi
Da Vinci Surgical SystemDa Vinci Surgical System
Systemic lupus erythematosusSystemic lupus erythematosus
Miniature Bull TerrierMiniature Bull Terrier
Wayne QuintonWayne Quinton
Leducq FoundationLeducq Foundation
Albert StarrAlbert Starr
DCHS1DCHS1
Interatrial sulcusInteratrial sulcus
TachycardiaTachycardia
Lasker AwardLasker Award
Quadricuspid aortic valveQuadricuspid aortic valve
Heart valveHeart valve
ഫലകം:Cardiac procedures - വിക്കിപീഡിയഫലകം:Cardiac procedures - വിക്കിപീഡിയ
Health of Frédéric ChopinHealth of Frédéric Chopin
AlkaptonuriaAlkaptonuria
හෘද රෝග - විකිපීඩියා, නිදහස් විශ්වකෝෂයහෘද රෝග - විකිපීඩියා, නිදහස් විශ්වකෝෂය
Atrial fibrillationAtrial fibrillation
Hypoxia (medical)Hypoxia (medical)
డౌన్ సిండ్రోమ్ - వికీపీడియాడౌన్ సిండ్రోమ్ - వికీపీడియా
Mitral valveMitral valve
CT scanCT scan
Blood pressureBlood pressure
Ventricle (heart)Ventricle (heart)
Cardiac resynchronization therapyCardiac resynchronization therapy
ಮಾನವನಲ್ಲಿ ರಕ್ತ ಪರಿಚಲನೆ - ವಿಕಿಪೀಡಿಯಮಾನವನಲ್ಲಿ ರಕ್ತ ಪರಿಚಲನೆ - ವಿಕಿಪೀಡಿಯ
Lown-Ganong-Levine syndromeLown-Ganong-Levine syndrome
പർക്കിൻജീ ഫൈബർ - വിക്കിപീഡിയപർക്കിൻജീ ഫൈബർ - വിക്കിപീഡിയ
Electrophysiology studyElectrophysiology study
Amlodipin bahasa Indonesia, ensiklopedia bebasAmlodipin bahasa Indonesia, ensiklopedia bebas
AsymptomaticAsymptomatic
Premature junctional contractionPremature junctional contraction
Списък на темите в Анатомията на Грей: V. Ангиология - УикипедияСписък на темите в Анатомията на Грей: V. Ангиология - Уикипедия
King Charles SpanielKing Charles Spaniel
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AnatomyOrganismsDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Mitral ValveMitral Valve ProlapseMitral Valve InsufficiencyMitral Valve StenosisAortic ValveMitral Valve AnnuloplastyHeart Valve DiseasesChordae TendineaeAortic Valve StenosisTricuspid ValveHeart Valve Prosthesis ImplantationHeart Valve ProsthesisAortic Valve InsufficiencyBioprosthesisPulmonary ValveEchocardiography, TransesophagealRheumatic Heart DiseaseEchocardiographyEchocardiography, Three-DimensionalCardiac Surgical ProceduresCardiac Valve AnnuloplastyPhonocardiographyEndocarditis, BacterialTricuspid Valve InsufficiencyEndocarditisEchocardiography, Doppler, ColorVenous ValvesHeart AuscultationEchocardiography, DopplerCatheterizationTreatment OutcomeCardiac CatheterizationProlapseReoperationMyxomaPapillary MusclesProsthesis DesignHeart AtriaHeart RuptureSuture TechniquesFollow-Up StudiesHeart NeoplasmsPostoperative ComplicationsCalcinosisHeart VentriclesKinetocardiographyHeart MurmursProsthesis FailureCardiopulmonary BypassBalloon ValvuloplastyHeart Defects, CongenitalHemodynamicsThoracotomyPulmonary Valve StenosisVentricular Outflow ObstructionHeart SoundsTime FactorsSeverity of Illness IndexVentricular Function, LeftAtrial FibrillationMarfan SyndromeHeart ValvesSternotomyCardiomyopathy, HypertrophicRetrospective StudiesSurgical Procedures, Minimally InvasiveHeart InjuriesAngiocardiographyThromboembolismEndocardial Cushion DefectsModels, CardiovascularPericardiumStroke VolumeCardiovascular Surgical ProceduresHeart SeptumPostoperative PeriodSurgical InstrumentsHeart DiseasesProspective StudiesHeart AneurysmRupture, SpontaneousDiastoleSystoleCineradiographyThoracic SurgerySternumLutembacher SyndromeEndocardial FibroelastosisDevice RemovalHeart Septal Defects, VentricularFibromaVentricular Dysfunction, LeftHeart Septal Defects, AtrialElectrocardiographyAtrial Function, LeftEmbolismFeasibility StudiesHeart Septal DefectsThrombosisTricuspid Valve ProlapseIleocecal ValveEquipment DesignCoronary Artery BypassAnemia, HemolyticBlood Flow VelocityPredictive Value of TestsMyocardial ContractionRisk AssessmentRecurrencePulmonary VeinsProsthesis-Related InfectionsRisk FactorsSheep
Alfieri Mitral Valve Repair | CirculationAlfieri Mitral Valve Repair | Circulation
Percutaneous Mitral Valve Repair Periprocedural Care: Preprocedural Planning, EquipmentPercutaneous Mitral Valve Repair Periprocedural Care: Preprocedural Planning, Equipment
Mitral Valve RegurgitationMitral Valve Regurgitation
Symptomatic Pulmonary Arterial Hypertension After Mitral Valve Surgery - Tabular View - ClinicalTrials.govSymptomatic Pulmonary Arterial Hypertension After Mitral Valve Surgery - Tabular View - ClinicalTrials.gov
Minimally Invasive Mitral Valve Surgery: The Evidence | CTSNetMinimally Invasive Mitral Valve Surgery: The Evidence | CTSNet
Coupled Fluid-Structural Analysis of Heart Mitral ValveCoupled Fluid-Structural Analysis of Heart Mitral Valve
Mitral Valve RegurgitationMitral Valve Regurgitation
Impact of Complications on Outcomes Following Aortic and Mitral Valve Replacements in the United States - RedorbitImpact of Complications on Outcomes Following Aortic and Mitral Valve Replacements in the United States - Redorbit
Mitral valve - WikipediaMitral valve - Wikipedia
Mitral valve repair - WikipediaMitral valve repair - Wikipedia
Mitral valve | anatomy | BritannicaMitral valve | anatomy | Britannica
Mitral Valve Prolapse | NHLBI, NIHMitral Valve Prolapse | NHLBI, NIH
Mitral Valve StenosisMitral Valve Stenosis
Mitral valve prolapse: MedlinePlus Medical EncyclopediaMitral valve prolapse: MedlinePlus Medical Encyclopedia
Category:Mitral valve insufficiency - Wikimedia CommonsCategory:Mitral valve insufficiency - Wikimedia Commons
Atrial Fibrillation and Mitral Valve RepairAtrial Fibrillation and Mitral Valve Repair
Mitral valve regurgitation: MedlinePlus Medical EncyclopediaMitral valve regurgitation: MedlinePlus Medical Encyclopedia
Mitral valve - WikipediaMitral valve - Wikipedia
Mitral Valve Regurgitation: Symptoms, Causes, Diagnosis, TreatmentMitral Valve Regurgitation: Symptoms, Causes, Diagnosis, Treatment
Mitral Valve Prolapse (for Parents) - Norton ChildrensMitral Valve Prolapse (for Parents) - Norton Children's
Patent US8070802 - Mitral valve system - Google PatentsPatent US8070802 - Mitral valve system - Google Patents
Mitral Valve Regurgitant Flow and Peripartum ChangeMitral Valve Regurgitant Flow and Peripartum Change
Mitral Valve Disease in CavaliersMitral Valve Disease in Cavaliers
Mitral Valve AbnormalitiesMitral Valve Abnormalities
Mitral valve stenosis - WikipediaMitral valve stenosis - Wikipedia
Patent US5716398 - Mitral valve rotator assembly - Google PatentsPatent US5716398 - Mitral valve rotator assembly - Google Patents
Adult patient with functioning prosthetic mitral valve withoutAdult patient with functioning prosthetic mitral valve without
Mitral Valve Prolapse | Johns Hopkins MedicineMitral Valve Prolapse | Johns Hopkins Medicine
Myxomatous mitral valve - Heart Disease - MedHelpMyxomatous mitral valve - Heart Disease - MedHelp
HealthDay - Mitral Valve ProlapseHealthDay - Mitral Valve Prolapse
An Atlas of Mitral Valve Imaging | SpringerLinkAn Atlas of Mitral Valve Imaging | SpringerLink
Mitral Valve: Definition, Anatomy, Function, Diagram, ConditionsMitral Valve: Definition, Anatomy, Function, Diagram, Conditions
Mitral valve prolapse syndrome definition | Drugs.comMitral valve prolapse syndrome definition | Drugs.com
Double Orifice Mitral Valve: Background, Pathophysiology, EpidemiologyDouble Orifice Mitral Valve: Background, Pathophysiology, Epidemiology
Mitral Valve ProlapseMitral Valve Prolapse
Mitral valve prolapse - Symptoms and causes - Mayo ClinicMitral valve prolapse - Symptoms and causes - Mayo Clinic
Mitral Valve leaflets appear myxomatous - Heart Disease - MedHelpMitral Valve leaflets appear myxomatous - Heart Disease - MedHelp
AnatomyOrganismsDiseasesAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
Mitral ValveMitral Valve ProlapseMitral Valve InsufficiencyMitral Valve StenosisAortic ValveMitral Valve AnnuloplastyHeart Valve DiseasesChordae TendineaeAortic Valve StenosisTricuspid ValveHeart Valve Prosthesis ImplantationHeart Valve ProsthesisAortic Valve InsufficiencyBioprosthesisPulmonary ValveEchocardiography, TransesophagealRheumatic Heart DiseaseEchocardiographyEchocardiography, Three-DimensionalCardiac Surgical ProceduresCardiac Valve AnnuloplastyPhonocardiographyEndocarditis, BacterialTricuspid Valve InsufficiencyEndocarditisEchocardiography, Doppler, ColorVenous ValvesHeart AuscultationEchocardiography, DopplerCatheterizationTreatment OutcomeCardiac CatheterizationProlapseReoperationMyxomaPapillary MusclesProsthesis DesignHeart AtriaHeart RuptureSuture TechniquesFollow-Up StudiesHeart NeoplasmsPostoperative ComplicationsCalcinosisHeart VentriclesKinetocardiographyHeart MurmursProsthesis FailureCardiopulmonary BypassBalloon ValvuloplastyHeart Defects, CongenitalHemodynamicsThoracotomyPulmonary Valve StenosisVentricular Outflow ObstructionHeart SoundsTime FactorsSeverity of Illness IndexVentricular Function, LeftAtrial FibrillationMarfan SyndromeHeart ValvesSternotomyCardiomyopathy, HypertrophicRetrospective StudiesSurgical Procedures, Minimally InvasiveHeart InjuriesAngiocardiographyThromboembolismEndocardial Cushion DefectsModels, CardiovascularPericardiumStroke VolumeCardiovascular Surgical ProceduresHeart SeptumPostoperative PeriodSurgical InstrumentsHeart DiseasesProspective StudiesHeart AneurysmRupture, SpontaneousDiastoleSystoleCineradiographyThoracic SurgerySternumLutembacher SyndromeEndocardial FibroelastosisDevice RemovalHeart Septal Defects, VentricularFibromaVentricular Dysfunction, LeftHeart Septal Defects, AtrialElectrocardiographyAtrial Function, LeftEmbolismFeasibility StudiesHeart Septal DefectsThrombosisTricuspid Valve ProlapseIleocecal ValveEquipment DesignCoronary Artery BypassAnemia, HemolyticBlood Flow VelocityPredictive Value of TestsMyocardial ContractionRisk AssessmentRecurrencePulmonary VeinsProsthesis-Related InfectionsRisk FactorsSheep
RegurgitationProlapseStenosisAnnulusLeafletsNormal mitralLeafletSurgicalSevereAnnuloplastyDiseaseSurgeryMinimallyLeft atriumEchocardiographyReplacementComplex mitral valveHeartAorticCardiacLeaflets of the mitral valveFlapsNormal mitral valveHeart's mitral valveValvularLeakProlapse syndromeMyxomatousBackwardTissueTreatment for mitralBack into the left atriumPeople with mitral valve prSymptoms of mitral valve prCoronaryComplicationsOccurs when the mitral valveDouble orifice mitral valveShortnessReplacement of the mitral valveRheumatic feverVentricularPosteriorLeaky mitral valvesReplace the mitral valveRepairAnnular calcificationHeart valvesTranscatheter mitral valveClick-murmur syndromeChordaeSyndromeForms of mitralChestLeaflet prolapseAbnormalCause of mitralTricuspid valvePatientsVentricle
Regurgitation33
Prolapse1
Stenosis6
Annulus7
Leaflets2
  • In order to support identification of potentially critical conditions resulting from some typical cardiosurgery operations, it is important to develop models of the mitral valve that enable prediction of both stress in the leaflets and blood flow pressure gradient and velocity across the valve during the cardiac cycle. (comsol.com)
  • The Clip is used to grasp and fasten together the valve leaflets. (wordpress.com)
Normal mitral1
Leaflet2
Surgical5
  • Despite surgical repair or replacement of the mitral valve, many patients remain symptomatic with an impaired ability to live an active lifestyle. (clinicaltrials.gov)
  • Another question is whether these results from the surgical field tell clinicians and researchers anything about repair versus replacement in the burgeoning field of percutaneous mitral valve interventions. (tctmd.com)
  • The 30 day results demonstrated low rates of serious adverse events and low mortality (6 percent (6/100) vs. 7.9 percent STS-predicted mortality for surgical valve replacement, or the Society of Thoracic Surgeons score used to predict long-term survival. (abbottinvestor.com)
  • Little is known about mitral valve (MV) surgical outcomes within the largest US federal health system - the Veterans Administration (VA) Health System. (keystoneperfusion.com)
  • Aims Ring annuloplasty is the gold standard of surgical repair in degenerative mitral valve disease. (elsevier.com)
Severe4
  • These data support current recommendations and substantiate the contention that, when feasible, MV repair should be the preferred treatment of severe degenerative MR and should remain a central condition of treatment algorithms and quality measure of valve centers," the authors conclude. (tctmd.com)
  • Tendyne is a first-of-its-kind device that offers patients with severe MR a life-saving treatment option, replacing their native mitral valve without open heart surgery to reduce their heart failure symptoms. (abbottinvestor.com)
  • If these symptoms are severe, and/or the valve is severely damaged, you may need valve repair or replacement. (stamfordhealth.org)
  • If your valve problem isn't too severe, your GP or cardiologist may recommend a "watchful waiting" approach, using medications to compensate for the valve that isn't working properly, regular check-ups and ultrasounds. (hcf.com.au)
Annuloplasty2
Disease11
Surgery23
Minimally6
Left atrium7
Echocardiography1
Replacement9
  • Overall, our initial results suggest that computer simulation may have the potential to improve patient selection for transcatheter mitral valve replacement in the presence of significant MAC. (nih.gov)
  • Transcatheter mitral valve replacement. (nih.gov)
  • What is mitral valve repair or replacement? (alberta.ca)
  • So if you do not have a surgeon capable of repairing a valve in your institution, then hopefully this kind of paper will make cardiologists think about sending their patients to another institution for a MV repair rather than having an MV replacement, because 20 years down the road, the difference in survival between the two groups-it speaks for itself. (tctmd.com)
  • So in degenerative MR, mitral repair is better than replacement, full stop," he said. (tctmd.com)
  • PARIS , May 23, 2018 /PRNewswire/ -- Abbott (NYSE: ABT) today announced favorable outcomes from the first 100 patients treated in a global study of its Tendyne Transcatheter Mitral Valve Replacement (TMVR) system, the first and only mitral replacement valve that is repositionable and fully retrievable to allow for more precise implantation, helping improve patient outcomes. (abbottinvestor.com)
  • VA hospitals favor mitral valve repair vs. replacement: 10-year rates mirror non-VA hospitals although wide variability in MV repair rates among centers noted, according to presentation at 96th AATS Annual Meeting. (keystoneperfusion.com)
  • At a mean follow-up of 11±3 years, all-cause mortality (P=0.12), need for mitral valve replacement (P=0.49), and cardiac re-hospitalization rate (P=0.57) resulted comparable between the two groups. (elsevier.com)
  • There may be alternatives to heart valve replacement, depending on your condition. (hcf.com.au)
Complex mitral valve1
  • Under the expert guidance of Dr. Adams, he has acquired further specialization in complex mitral valve repair using less invasive techniques. (mitralvalverepair.org)
Heart12
Aortic15
Cardiac30
Leaflets of the mitral valve6
Flaps33
Normal mitral valve5
Heart's mitral valve2
Valvular2
Leak11
  • Rarely, blood can leak the wrong way through the floppy valve. (nih.gov)
  • Sixteen of the 31 late deaths were definitely attributable to the presence of the prosthesis: systemic arterial emboli (eight patients), valve thrombosis (two), perivalvular leak (one), ball variance (two), endocarditis (two), and intracerebral hemorrhage due to anticoagulants (one). (ahajournals.org)
  • As one ages, this makes the valve prone to leak. (upmc.com)
  • Rheumatic fever - this can also lead to scarring of the leaflets and cause the valve to leak. (upmc.com)
  • Heart attack or lack of blood supply to the heart muscle - this can stretch the left ventricle and the mitral valve, causing it to leak. (upmc.com)
  • Ultrasound guides the device to the mitral valve leak for to repair. (uvahealth.com)
  • Specific to these diseases, the mitral valve is normal, but the leaflet edges do not meet creating a large leak, because its supporting structures are pulled away and outward by the dilatation of the heart. (maimonidesmed.org)
  • Other conditions, too - for example, congenital problems and degenerative processes - constricted valves or made them leak. (laskerfoundation.org)
  • Birth defects, age-related changes, infections, or other conditions can cause one or more of the heart valves not to open fully or to let blood leak back into the heart chambers. (gopetsamerica.com)
  • This is dangerous because when the leaflets in the valve don't meet correctly, blood may leak backwards into the lungs each time the heart pumps. (wikidoc.org)
  • Many mitral valves can be repaired, especially if the leak is due to wear and tear. (wikidoc.org)
Prolapse syndrome3
Myxomatous1
Backward6
  • When the mitral valve doesn't close all the way, blood flows backward into the upper heart chamber (atrium) from the lower chamber as it contracts. (medlineplus.gov)
  • This is one of the heart's four valves that help prevent blood from flowing backward as it moves through the heart. (healthline.com)
  • But this new procedure is a breakthrough because we can essentially stop the backward flow of the blood through the leaky valve and decrease the patient's risk of heart failure without any stitching involved. (prweb.com)
  • Your mitral valve separates these two chambers and keeps the blood from flowing backward. (cardiosmart.org)
  • Once the catheter reaches your heart, a dime-sized clip clamps the improperly working valve, allowing it to close more tightly and reducing backward blood flow. (sutterhealth.org)
  • The heart's valves open so blood can move forward, and then close to keep it from moving backward. (utmedicalcenter.org)
Tissue32
Treatment for mitral1
  • When treatment for mitral valve prolapse is required, several options are considered, the first being medications to improve heart function and control heart rhythm. (wisegeek.com)
Back into the left atrium4
People with mitral valve pr5
Symptoms of mitral valve pr3
Coronary2
Complications3
Occurs when the mitral valve1
Double orifice mitral valve9
  • Double orifice mitral valve (DOMV) is an uncommon anomaly that was first described by Greenfield in 1876. (medscape.com)
  • [ 3 ] Although double orifice mitral valve may allow normal blood flow between the left atrium and LV, it can substantially obstruct mitral valve inflow or produce mitral valve incompetence. (medscape.com)
  • Recognition of double orifice mitral valve and awareness of the anatomic variations are important to achieve good therapeutic results. (medscape.com)
  • In this type of double orifice mitral valve, dilatation of the posteromedial orifice is feasible by means of balloon valvuloplasty. (medscape.com)
  • Double orifice mitral valve was always associated with an anomaly of the subvalvular apparatus because, by definition, a separate tensor apparatus is attached to each orifice. (medscape.com)
  • In another published clinical series of 18 patients with double orifice mitral valve and intact AV septum, Das et al found that double orifice mitral valve was most commonly associated with left sided obstructed lesions in 39% of the cases and with ventricular septal defects (VSDs) in 17% of the cases. (medscape.com)
  • A, TEE short-axis view shows double-orifice mitral valve (asterisks) and the Alfieri repair site (arrow). (ahajournals.org)
  • B, TEE 2-chamber view shows double-orifice mitral valve and region of repair (arrow). (ahajournals.org)
  • C, TEE with Doppler color flow characteristics through double-orifice mitral valve. (ahajournals.org)
Shortness4
  • Mitral valve involvement is usually symptomless initially but may lead to left ventricular failure with shortness of breath. (britannica.com)
  • When the valve does not work properly, you may experience a variety of side effects, including fatigue and shortness of breath. (upmc.com)
  • Changes in your mitral valve are causing major heart symptoms, such as shortness of breath, leg swelling, or heart failure. (floridahealthfinder.gov)
  • Some symptoms of patients that need mitral valve repair or replacement include: sensations of feeling the heart beat, chest pain, hard to breathe especially after activity, fatigue, coughing, and shortness of breath while lying flat. (wikidoc.org)
Replacement of the mitral valve1
  • The development of the heart-lung machine in the 1950s paved the way for replacement of the mitral valve with an artificial valve in the 1960s. (wikipedia.org)
Rheumatic fever3
Ventricular9
Posterior8
Leaky mitral valves1
  • A device approved today by the Federal Drug Administration (FDA) to treat leaky mitral valves was first used in this region as part of a clinical trial at the Washington University and Barnes-Jewish Heart & Vascular Center . (prweb.com)
Replace the mitral valve2
  • Instead, we replace the mitral valve with a bioprosthetic or a mechanical valve. (uvahealth.com)
  • A small cut is made in the left side of your heart so the surgeon can repair or replace the mitral valve. (floridahealthfinder.gov)
Repair42
Annular calcification2
  • Caseous necrosis of the mitral valve is a rare form of mitral annular calcification (MAC) in which there is high atherosclerotic burden with central 'caseous' necrosis, which can resemble a tumor. (massgeneral.org)
  • This represents a rare form of mitral annular calcification of uncertain pathophysiology. (aerzteblatt.de)
Heart valves9
Transcatheter mitral valve3
Click-murmur syndrome2
Chordae13
Syndrome2
Forms of mitral2
Chest2
Leaflet prolapse1
Abnormal1
Cause of mitral2
Tricuspid valve4
Patients15
Ventricle32
The mitral valve
The mitral valve (netdoctor.co.uk)
Breakthrough in mitral valve treatment - Harvard Health
Breakthrough in mitral valve treatment - Harvard Health (health.harvard.edu)
Mitral Valve Regurgitation
Mitral Valve Regurgitation (cardiosmart.org)
JCDR - Ball valve thrombus, Mitral stenosis, Rheumatic heart disease
JCDR - Ball valve thrombus, Mitral stenosis, Rheumatic heart disease (jcdr.net)
Mitral valve - Wikipedia
Mitral valve - Wikipedia (en.wikipedia.org)
Mitral Valve Prolapse
Mitral Valve Prolapse (kidshealth.org)
Mitral Valve Surgery | Robert S. Bonser | Springer
Mitral Valve Surgery | Robert S. Bonser | Springer (springer.com)
Follistatin-like 1 in development and human diseases | SpringerLink
Follistatin-like 1 in development and human diseases | SpringerLink (link.springer.com)
Category:Mitral valve insufficiency - Wikimedia Commons
Category:Mitral valve insufficiency - Wikimedia Commons (commons.wikimedia.org)
Taking class of commonly-prescribed antibiotics more than doubles your chance of a 'leaky valve' | Daily Mail Online
Taking class of commonly-prescribed antibiotics more than doubles your chance of a 'leaky valve' | Daily Mail Online (dailymail.co.uk)
Left atrial enlargement: Symptoms, causes, and treatment
Left atrial enlargement: Symptoms, causes, and treatment (medicalnewstoday.com)
Https://www.medicalnewstoday.com/articles/321242.php
Https://www.medicalnewstoday.com/articles/321242.php (medicalnewstoday.com)
KidsHealth.org Search results : mvp - Nemours KidsHealth
KidsHealth.org Search results : mvp - Nemours KidsHealth (kidshealth.org)
Heart Valve Disorders: Causes, Symptoms and Diagnosis
Heart Valve Disorders: Causes, Symptoms and Diagnosis (healthline.com)
Mitral Valve Prolapse | Johns Hopkins Medicine
Mitral Valve Prolapse | Johns Hopkins Medicine (hopkinsmedicine.org)
Double Orifice Mitral Valve: Background, Pathophysiology, Epidemiology
Double Orifice Mitral Valve: Background, Pathophysiology, Epidemiology (emedicine.medscape.com)
Mitral Valve Disease | Cardiology Medicine | MBBS | sqadia.com
Mitral Valve Disease | Cardiology Medicine | MBBS | sqadia.com (sqadia.com)
Heart-Encyclopedia - M
Heart-Encyclopedia - M (heart.org)
Every Organ Tells a Story 4: A History of Anatomical Terms | HubPages
Every Organ Tells a Story 4: A History of Anatomical Terms | HubPages (hubpages.com)
Mitral Valve Prolapse | Cardiology Medicine | MBBS Lectures | sqadia.com
Mitral Valve Prolapse | Cardiology Medicine | MBBS Lectures | sqadia.com (sqadia.com)
July 1981 - Volume 11 - Issue 7 : Nursing2019
July 1981 - Volume 11 - Issue 7 : Nursing2019 (journals.lww.com)
Stem Cells Programmed With MiR-133, a New Alternative Therapy For the Damaged Heart
Stem Cells Programmed With MiR-133, a New Alternative Therapy For the Damaged Heart (medindia.net)
Dark Chocolate may Prevent Heart Disease
Dark Chocolate may Prevent Heart Disease (medindia.net)