The lone species of the genus Asfivirus. It infects domestic and wild pigs, warthogs, and bushpigs. Disease is endemic in domestic swine in many African countries and Sardinia. Soft ticks of the genus Ornithodoros are also infected and act as vectors.
A sometimes fatal ASFIVIRUS infection of pigs, characterized by fever, cough, diarrhea, hemorrhagic lymph nodes, and edema of the gallbladder. It is transmitted between domestic swine by direct contact, ingestion of infected meat, or fomites, or mechanically by biting flies or soft ticks (genus Ornithodoros).
A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.
A family of large icosahedral DNA viruses infecting insects and poikilothermic vertebrates. Genera include IRIDOVIRUS; RANAVIRUS; Chloriridovirus; Megalocytivirus; and Lymphocystivirus.
An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.
Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA).
A family of nucleocytoplasmic, large, double-stranded DNA viruses with extremely complex genomes.
A CELL LINE derived from the kidney of the African green (vervet) monkey, (CERCOPITHECUS AETHIOPS) used primarily in virus replication studies and plaque assays.
Viruses whose nucleic acid is DNA.
A family of double-stranded DNA viruses containing one genus Asfivirus. It is the source of AFRICAN SWINE FEVER.
A genus of softbacked TICKS, in the family ARGASIDAE, serving as the vector of BORRELIA, causing RELAPSING FEVER, and of the AFRICAN SWINE FEVER VIRUS.
A species of CERCOPITHECUS containing three subspecies: C. tantalus, C. pygerythrus, and C. sabeus. They are found in the forests and savannah of Africa. The African green monkey (C. pygerythrus) is the natural host of SIMIAN IMMUNODEFICIENCY VIRUS and is used in AIDS research.
Viral proteins that are components of the mature assembled VIRUS PARTICLES. They may include nucleocapsid core proteins (gag proteins), enzymes packaged within the virus particle (pol proteins), and membrane components (env proteins). These do not include the proteins encoded in the VIRAL GENOME that are produced in infected cells but which are not packaged in the mature virus particle,i.e. the so called non-structural proteins (VIRAL NONSTRUCTURAL PROTEINS).
Proteins found in any species of virus.
The type species of the FLAVIVIRUS genus. Principal vector transmission to humans is by AEDES spp. mosquitoes.
A phenomenon manifested by an agent or substance adhering to or being adsorbed on the surface of a red blood cell, as tuberculin can be adsorbed on red blood cells under certain conditions. (Stedman, 25th ed)
Proteins which are synthesized as a single polymer and then cleaved into several distinct proteins.
Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories.
A mosquito-borne species of the PHLEBOVIRUS genus found in eastern, central, and southern Africa, producing massive hepatitis, abortion, and death in sheep, goats, cattle, and other animals. It also has caused disease in humans.
The functional hereditary units of VIRUSES.
A genus of free-living soil amoebae that produces no flagellate stage. Its organisms are pathogens for several infections in humans and have been found in the eye, bone, brain, and respiratory tract.
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
The process of intracellular viral multiplication, consisting of the synthesis of PROTEINS; NUCLEIC ACIDS; and sometimes LIPIDS, and their assembly into a new infectious particle.
The assembly of VIRAL STRUCTURAL PROTEINS and nucleic acid (VIRAL DNA or VIRAL RNA) to form a VIRUS PARTICLE.
Deoxyribonucleic acid that makes up the genetic material of viruses.
A species of SWINE, in the family Suidae, comprising a number of subspecies including the domestic pig Sus scrofa domestica.
The complete genetic complement contained in a DNA or RNA molecule in a virus.
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
The infective system of a virus, composed of the viral genome, a protein core, and a protein coat called a capsid, which may be naked or enclosed in a lipoprotein envelope called the peplos.
Diseases of domestic swine and of the wild boar of the genus Sus.
The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence.
Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)
An abnormal elevation of body temperature, usually as a result of a pathologic process.
A species of NAIROVIRUS of the family BUNYAVIRIDAE. It is primarily transmitted by ticks and causes a severe, often fatal disease in humans.
Visible morphologic changes in cells infected with viruses. It includes shutdown of cellular RNA and protein synthesis, cell fusion, release of lysosomal enzymes, changes in cell membrane permeability, diffuse changes in intracellular structures, presence of viral inclusion bodies, and chromosomal aberrations. It excludes malignant transformation, which is CELL TRANSFORMATION, VIRAL. Viral cytopathogenic effects provide a valuable method for identifying and classifying the infecting viruses.
Immunoglobulins produced in response to VIRAL ANTIGENS.
An acute infectious disease primarily of the tropics, caused by a virus and transmitted to man by mosquitoes of the genera Aedes and Haemagogus. The severe form is characterized by fever, HEMOLYTIC JAUNDICE, and renal damage.
The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Established cell cultures that have the potential to propagate indefinitely.
An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
A republic in southern Africa east of ZAMBIA and MOZAMBIQUE. Its capital is Lilongwe. It was formerly called Nyasaland.
The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species.
The outer protein protective shell of a virus, which protects the viral nucleic acid.
The type species of ORTHOPOXVIRUS, related to COWPOX VIRUS, but whose true origin is unknown. It has been used as a live vaccine against SMALLPOX. It is also used as a vector for inserting foreign DNA into animals. Rabbitpox virus is a subspecies of VACCINIA VIRUS.
A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.
The relationships of groups of organisms as reflected by their genetic makeup.
A kingdom of hyperthermophilic ARCHAEA found in diverse environments.
DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair.
A genus of ameboid protozoa. Characteristics include a vesicular nucleus and the formation of several lodopodia, one of which is dominant at a given time. Reproduction occurs asexually by binary fission.
Salas, María L.; Andrés, Germán (2013). "African swine fever virus morphogenesis". Virus Research. 173: 29-41. doi:10.1016/j. ... For example, viroplasms of mimivirus have a similar size to the nucleus of its host, the amoeba Acanthamoeba polyphaga. A virus ... Viroplasms have been found in the cauliflower mosaic virus, rotavirus, vaccinia virus and the rice dwarf virus. These appear ... "Ultrastructural Characterization of the Giant Volcano-like Virus Factory of Acanthamoeba polyphaga Mimivirus". PLoS ONE. 2 (3 ...
ASFV has similarities to the other large DNA viruses, e.g., poxvirus, iridovirus, and mimivirus. In common with other viral ... "African Swine Fever (ASF)". PigSite. Archived from the original on 2018-06-14. Retrieved 2010-01-28. "African Swine Fever". ... In July, 3 farms discovered African swine fever in Estonia. [...] African swine fever spreads to farmed pigs, 500 animals to be ... Viruses portal Veterinary virology Dixon; et al. (2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. ...
... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus". ... Viruses portal Nucleocytoplasmic large DNA viruses Pithovirus Pandoravirus Klosneuvirus Mimivirus Cafeteria roenbergensis virus ... due to their having the largest capsid diameters of all known viruses. Giant viruses replicate within large spheroidal virus ... A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. They ...
This virus is the cause of African swine fever. Some of the symptoms for this flu include fever, high pulse, fast breathing, ... Later it appeared that the viruses of the Organic Lake Phycodna Group (OLPG) are more related to Mimiviruses than to ... "African swine fever (ASF) , animal disease". Encyclopedia Britannica. Retrieved 2017-12-07. "Iridoviridae-Iridoviridae-dsDNA ... the difference is that the African swine flu can not be cured. There is no vaccine developed to fight this virus. Order ...
Famili Asfarviridae - includes African swine fever virus. *Famili Baculoviridae. *Famili Coccolithoviridae. *Famili ... Mimivirus. Grup II[sunting , sunting sumber]. *Bakteriofage yang belum dibagi *Famili Inoviridae ... Virus DNA adalah virus yang masuk pada baik Grup I atau Grup II pada sistem klasifikasi Baltimore terhadap virus. Virus ini ... "ICTVdb Index of Viruses: Virus Taxonomy, 8th Reports of the International Committee on Taxonomy of Viruses: Listing in ...
... and the large eukaryal DNA viruses: the African swine fever virus (Asfarviridae), Chlorella viruses (Phycodnaviridae) and ... Mutsafi, Y; Zauberman, N; Sabanay, I; Minsky, A (30 Mar 2010). "Vaccinia-like cytoplasmic replication of the giant Mimivirus". ... Orthopox: smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus, rabbitpox virus; Parapox: orf virus, ... Ectromelia virus and Monkeypox virus do not group closely with any other member. Variola virus and Camelpox virus form a ...
Yellow fever originated in Africa and the virus was brought to the Americas on cargo ships, which were harbouring the Aedes ... The many diseases caused by viruses included foot-and-mouth disease, rinderpest of cattle, avian and swine influenza, swine ... Arslan D, Legendre M, Seltzer V, Abergel C, Claverie JM (2011). "Distant mimivirus relative with a larger genome highlights the ... yellow fever virus, dengue virus and Pappataci fever virus. More than 100 of such viruses are now known to cause human diseases ...
... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. ... Genus Cafeteriavirus (mit einziger Species Cafeteria roenbergensis virus). *Genus Mimivirus (mit einziger Species Acanthamoeba ... Usutu-Virus - en. Usutu virus (USUV), Zika-Virus - en. Zika virus (ZIKV), sowie Gelbfieber-Virus - en. Yellow fever virus (YFV) ... Genus ‚Negevirus', mit Species ‚Blackford virus', ‚Bofa virus', ‚Buckhurst virus', ‚Marsac virus', sowie ‚Muthill virus'[53] ...
... and African swine fever virus, NP_042738. *. We thank T. Rowbotham for providing the isolate now identified as Mimivirus; W. F ... Mimivirus is a nucleocytoplasmic large DNA virus (NCLDV). This group of viruses includes four other families, including the ... Mimivirus appears as a deep branch in the phylogenetic tree (Fig. 1C), suggesting early divergence from other virus families. ... Accession numbers: Mimivirus, ; Cowpox virus, NP_619839; Lymantria dispar nucleopolyhedrovirus, NP_047757; Paramecium bursia ...
ASFV has similarities to the other large DNA viruses, e.g., poxvirus, iridovirus, and mimivirus. In common with other viral ... "African Swine Fever (ASF)". PigSite. Archived from the original on 2018-06-14. Retrieved 2010-01-28. "African Swine Fever". ... In July, 3 farms discovered African swine fever in Estonia. [...] African swine fever spreads to farmed pigs, 500 animals to be ... Viruses portal Veterinary virology Dixon; et al. (2008). "African Swine Fever Virus". Animal Viruses: Molecular Biology. ...
Detection of African swine fever virus-like sequences in ponds in the Mississippi Delta through metagenomic sequencing. Virus ... Viruses with more than 1000 genes: Mamavirus, a new Acanthamoeba castellanii mimivirus strain, and reannotation of mimivirus ... NC_009898.1), African swine fever virus (accession no. NC_001659.1), faustovirus E12, invertebrate iridescent virus 6 ( ... Detection of novel sequences related to African swine fever virus in human serum and sewage. J Virol 83:13019-13025. doi: ...
Salas, María L.; Andrés, Germán (2013). "African swine fever virus morphogenesis". Virus Research. 173: 29-41. doi:10.1016/j. ... For example, viroplasms of mimivirus have a similar size to the nucleus of its host, the amoeba Acanthamoeba polyphaga. A virus ... Viroplasms have been found in the cauliflower mosaic virus, rotavirus, vaccinia virus and the rice dwarf virus. These appear ... "Ultrastructural Characterization of the Giant Volcano-like Virus Factory of Acanthamoeba polyphaga Mimivirus". PLoS ONE. 2 (3 ...
... as for instance Mimivirus (1) and African swine fever virus. Where the structure is known, the double jelly-roll forms a ... Mimivirus is one of the largest known viruses, first discovered in a water tower during a search for the cause of a hospital- ... 2008) Distinct DNA exit and packaging portals in the virus Acanthamoeba polyphaga mimivirus. PLoS Biol 6(5):e114. ... "Sputnik" is a dsDNA virus, referred to as a virophage, that is coassembled with Mimivirus in the host amoeba. We have used cryo ...
Inteins are found in all three domains of life and in viruses, but have a very sporadic distribution. Only a small number of ... African swine fever virus AAA65283. • Emiliana huxleyi virus 86 CAI65861. • Acanthamoeba polyphaga mimivirus AAQ09583 ... to an RNA polymerase from African swine fever virus (ASFV), a large double-stranded DNA virus that is a member of the nuclear- ... represent ORFs whose best matches among all the protein sequences in GenBank are proteins coded by African swine-fever virus ( ...
Additional studies on African swine fever virus (27), Paramecium bursaria chlorella virus-1 (28), and Acanthamoeba polyphaga ... Mimivirus: leading the way in the discovery of giant viruses of amoebae. Nat Rev Microbiol 15:243-254. doi:10.1038/nrmicro. ... Replication of African swine fever virus DNA in infected cells. Virology 257:524-536. doi:10.1006/viro.1999.9704. ... African swine fever virus assembles a single membrane derived from rupture of the endoplasmic reticulum. Cell Microbiol 17:1683 ...
... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus". ... Viruses portal Nucleocytoplasmic large DNA viruses Pithovirus Pandoravirus Klosneuvirus Mimivirus Cafeteria roenbergensis virus ... due to their having the largest capsid diameters of all known viruses. Giant viruses replicate within large spheroidal virus ... A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. They ...
Aedes taeniorhynchus iridescent virus (NC_008187), African swine fever virus (NC_001659), Amsacta moorei entomopoxvirus (NC_ ... The saga of giant viruses (i.e. visible by light microscopy) started in 2003 with the discovery of Mimivirus. Two additional ... Myxoma virus (NC_001132), Neodiprion abietis NPV (NC_008252), Orf virus (NC_005336), Ostreococcus lucimarinus virus OlV1 (NC_ ... This led to the discovery and characterization of additional Mimivirus-like viruses now gathered into their own distinct family ...
Recombinant African swine fever virus Transmembrane protein C257L(Ba71V-066). CSB-CF723819AEJ. in vitro E.coli expression ... Recombinant Acanthamoeba polyphaga mimivirus Uncharacterized protein L778(MIMI_L778). CSB-CF713231ADAZ. in vitro E.coli ... Recombinant Bovine respiratory syncytial virus Major surface glycoprotein G(G). CSB-CF737465BDAK. in vitro E.coli expression ... Recombinant Bovine respiratory syncytial virus Major surface glycoprotein G(G). CSB-CF515527BVN. in vitro E.coli expression ...
... the discovery of Mimivirus, a virus infecting Acanthamoeba, initiated a reappraisal of the upper limits of the viral world, ... African swine fever virus (ASFV) is a complex nucleocytoplasmic large DNA virus (NCLDV) that causes a devastating swine disease ... The cryo-EM Structure of African Swine Fever Virus Unravels a Unique Architecture Comprising Two Icosahedral Protein Capsids ... Mimivirus, a DNA virus infecting acanthamoeba, was for a long time the largest known virus both in terms of particle size and ...
Our taxon co-occurrence analysis revealed a potential association between viruses of the Megaviridae family and eukaryotes ... constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of ... and that metagenomic sequence analyses promise to shed new light on the biodiversity of marine viruses and their interactions ... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. J ...
... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. ... Claverie JM, Ogata H, Audic S, Abergel C, Suhre K, Fournier PE., Mimivirus and the emerging concept of "giant" virus. Virus Res ... Claverie J.-M, Abergel C, Ogata H., Mimivirus. Lesser Known Large dsDNA Viruses (2009) *Monier A, Larsen JB, Sandaa RA, Bratbak ... Marine mimivirus relatives are probably large algal viruses. Virol J 5, 12 (2008) [pubmed] *Yoshida T, Nagasaki K, Takashima Y ...
dna viruses*open reading frames*rickettsia felis*african swine fever virus*inteins*viral genes*dinoflagellida*rickettsia ... Mimivirus and the emerging concept of "giant" virus. Jean Michel Claverie. Information Genomique et Structurale, CNRS UPR 2589 ... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. ... sequence similarity between the dinoflagellate-infecting marine girus and the terrestrial pathogen African swine fever virus. ...
... how immune systems counteract viruses, and how viruses travel from host to host. ... how viruses are named, how their genes work, how they copy and package themselves, how they interact with their hosts, ... African swine fever virus. *Bluetongue virus. *Boid Inclusion body disease virus. *Bornadisease virus ... Acanthamoeba polyphaga mimivirus. *Curvularia thermal tolerance virus. *Helminthosporium victoriae virus 190S. *Penicillium ...
... a feature that can also be seen in some other users of the NCLDVs such as African Swine Fever Virus [7]. Within these two ... Mimivirus, the prototypic member of the new category of (electronic. starfish-like. Posted on December 8, 2019. by ... Mimivirus, the prototypic member of the new category of (electronic. starfish-like framework Phlorizin manufacturer was ... The coloring is founded on radial length from the guts of the virus. Gray = 0C1,800 ?; red = 1,800C2,100 ?; rainbow coloring ...
Famili Asfarviridae - includes African swine fever virus. *Famili Baculoviridae. *Famili Coccolithoviridae. *Famili ... Mimivirus. Grup II[sunting , sunting sumber]. *Bakteriofage yang belum dibagi *Famili Inoviridae ... Virus DNA adalah virus yang masuk pada baik Grup I atau Grup II pada sistem klasifikasi Baltimore terhadap virus. Virus ini ... "ICTVdb Index of Viruses: Virus Taxonomy, 8th Reports of the International Committee on Taxonomy of Viruses: Listing in ...
African swine fever virus BA71V Agaricus bisporus Agkistrodon contortrix contortrix Agrobacterium fabrum str. C58 ... Acanthamoeba polyphaga mimivirus Acetoanaerobium sticklandii DSM 519 Acidaminococcus fermentans DSM 20731 Acinetobacter ...
Family Asfarviridae - includes African swine fever virus. *Family Baculoviridae. *Family Coccolithoviridae. *Family ... Family Poxviridae - includes Cowpox virus, smallpox. *Family Rudiviridae. *Family Tectiviridae. *Unassigned genera * Mimivirus ... viral haemorrhagic fevers. Mosquito (Dengue fever - Chikungunya - Rift Valley fever - Yellow fever - Onyongnyong - West Nile ... de:DNA-Virus et:DNA-viirusedid:Virus DNA nl:DNA-virussv:DNA-virus ...
African swine fever virus BA71V (U18466), species African swine fever virus, genus Asfivirus ... In contrast, capsid-encoding genes with introns and exons can be found in other viruses of amoeba such as a mimivirus infecting ... when it was removed as a member of the unassigned genus African swine fever virus group, (renamed African swine fever-like ... Figure 3.Asfarviridae. African swine fever virus infectious cycle. Virus enters the cell by a complex process involving ...
Emergence of African Swine Fever Virus, Northwestern Iran. 16. 12. Dispatch. 2010. 12. ... Pulmonary Infection Related to Mimivirus in Patient with Primary Ciliary Dyskinesia. 26. 10. Research Letter. 2020. 10. ... Systematic Review and Meta-analysis of Postexposure Prophylaxis for Crimean-Congo Hemorrhagic Fever Virus among Healthcare ... Peste des Petits Ruminants Virus in Vulnerable Wild Small Ruminants, Iran, 2014-2016. 23. 4. Research Letter. 2017. 4. ...
Recent progress in isolation of new viruses and genome sequencing resulted in a substantial expansion of the NCLDV diversity, ... Using previously developed computational methods for orthology identification, 1445 Nucleo-Cytoplasmic Virus Orthologous Groups ... Evolutionary reconstructions employing NCVOGs point to complex ancestral viruses. ... indicating that this virus encoded a complex machinery of replication, expression and morphogenesis that made it relatively ...
In this paper, the DL method is used to analyze the whole-proteome phylogeny of 124 large dsDNA viruses and 30 parvoviruses, ... The trees from our analyses are in good agreement to the latest classification of large dsDNA viruses and parvoviruses by the ... some alignment-free methods such as the CV Tree method can be used for recovering the phylogeny of large dsDNA viruses, but ... The present method provides a new way for recovering the phylogeny of large dsDNA viruses and parvoviruses, and also some ...
Undetected Circulation of African Swine Fever in Wild Boar, Asia [PDF - 822 KB - 3 pages] T. Vergne et al. View Abstract. Cite ... We evaluated the prevalence of Rift Valley fever virus IgG and IgM in human serum samples (n = 1,276) collected in 2013-2014 in ... Pulmonary Infection Related to Mimivirus in Patient with Primary Ciliary Dyskinesia [PDF - 661 KB - 3 pages] F. Sakhaee et al. ... African swine fever is a growing threat to the livestock industry. We examined data indicating that in most countries in Asia, ...
Mayaro Fever Virus, Brazilian Amazon. 15. 11. Dispatch. 2009. 11. Oropouche Fever Outbreak, Manaus, Brazil, 2007-2008. 15. 12. ... Spread of Chikungunya Virus East/Central/South African Genotype in Northeast Brazil. 23. 10. Research Letter. 2017. 10. ... Influenza A Viruses of Human Origin in Swine, Brazil. 21. 8. Research. 2015. 8. ... Mimivirus Circulation among Wild and Domestic Mammals, Amazon Region, Brazil. 20. 3. Dispatch. 2014. 3. ...
Vincent, Dick, Alan, and Hamish Young focus on the new H1N1 influenza virus, which originated in swine and is likely to be the ... return of swine flu to humans, spread of polio in Africa, and listener email. ... Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome ... TWiV 31: Fever plus cough or sore throat *May 10, 2009. Vincent, Dick, Alan, and Marc Pelletier summarize the past weeks ...
... as with CroV and influenza viruses, or with African swine fever and faustovirus, an NCLDV that Klose and Rossmann reconstructed ... La Scola, the virus hunter in Marseille who was the first author on the 2003 paper that identified Mimivirus as a virus and the ... Viruses of viruses. Even viruses have predators. Over eons of acquiring and shedding genes, a number of giant viruses picked up ... While mimivirus was the first identified nucleocytoplasmic large DNA virus, or NCLDV, it wasnt alone for long. Giant viruses ...
This chapter will give an account of the history of the discovery of viruses,… ... Introduction to Viruses Viruses as a concept are just a little younger than bacteria - they were first described only in the ... 1930: the South African-born Max Theiler - son of Sir Arnold, also at Harvard - showed that yellow fever virus could be ... Unlike other satellite viruses, the virophage uses the mimiviruss cytoplasmic virus factories for transcription, replication, ...
Immunisation of pigs by DNA prime and recombinant vaccinia virus boost to identify and rank African swine fever virus ... Single mimivirus particles intercepted and imaged with an X-ray laser. Nature 2011, 470 (7332), 78-81.. ... "Conformational landscape of a virus by single-particle X-ray scattering." nAture methods 14, no. 9 (2017): 877. ...
  • For example, viroplasms of mimivirus have a similar size to the nucleus of its host, the amoeba Acanthamoeba polyphaga. (wikipedia.org)
  • Mimivirus has a dsDNA genome and uses Acanthamoeba as its natural host ( 1 ). (pnas.org)
  • Giant viruses were first described in 2003, with the discovery of Acanthamoeba polyphaga mimivirus ( 1 , 2 ). (asm.org)
  • Mimivirus, a DNA virus infecting acanthamoeba, was for a long time the largest known virus both in terms of particle size and gene content. (nih.gov)
  • The largest known DNA viruses infect Acanthamoeba and belong to two markedly different families. (nih.gov)
  • It took several years for the French microbiologists Didier Raoult and Bernard La Scola to recognize that Bradfordococcus was, in fact, a virus nearly as large as the amoeba Acanthamoeba polyphaga that it was hunting. (asbmb.org)
  • In a paper published in the journal Science in 2003, La Scola, Raoult and their colleagues renamed the pathogen Acanthamoeba polyphaga mimivirus, and "mimivirus" - short for "mimicking microbe" - stuck. (asbmb.org)
  • In common with other viral hemorrhagic fevers, the main target cells for replication are those of monocyte, macrophage lineage. (wikipedia.org)
  • Viral membrane proteins with similarity to cellular adhesion proteins modulate interaction of virus-infected cells and extracellular virions with host components. (wikipedia.org)
  • The viroplasm formation is caused by the interactions between the virus and the infected cell, where viral products and cell elements are confined. (wikipedia.org)
  • A virus can induce changes in composition and organization of host cell cytoskeletal and membrane compartments, depending on the step of the viral replication cycle. (wikipedia.org)
  • Some of the membrane components are used for viral replication while some others will be modified to produce viral envelopes, when the viruses are enveloped. (wikipedia.org)
  • Wrapping the viroplasm with a membrane, concentrates the viral components required for the genome replication and the morphogenesis of new virus particles, so it increases the efficiency of the processes. (wikipedia.org)
  • EM images suggest that Sputnik virus matures in viral factories together with Mimivirus itself ( 5 ). (pnas.org)
  • Using a high-throughput strategy to isolate new giant viruses from their original protozoan hosts, we obtained eight isolates of a new giant viral lineage from Vermamoeba vermiformis , the most common free-living protist found in human environments. (asm.org)
  • Phylogenetic analysis of the core viral genes showed that faustovirus is distantly related to the mammalian pathogen African swine fever virus, but it encodes ≈3 times more mosaic gene complements. (asm.org)
  • Nucleocytoplasmic large DNA viruses (NCLDVs) can recruit host-derived open membrane precursors to form their inner viral membrane. (asm.org)
  • Viral replication in giant viruses occurs within large circular virus factories located within the cytoplasm of the infected host cell, similar to the replication mechanism used by Poxviridae, though whether this mechanism is employed by all giant viruses or only mimivirus and the related mamavirus has yet to be determined. (wikipedia.org)
  • NCLDVs include viruses with very large virion particles, which do not pass through 0.2-μm filters typically used in viral metagenomics to separate free viruses from other organisms ( Van Etten, 2011 ). (nature.com)
  • Recent progress in isolation of new viruses and genome sequencing resulted in a substantial expansion of the NCLDV diversity, resulting in additional opportunities for comparative genomic analysis, and a demand for a comprehensive classification of viral genes. (biomedcentral.com)
  • One of the most expansive, apparently monophyletic divisions of viruses consists of at least 6 families of eukaryotic viruses with large DNA genomes including Poxviridae, an expansive viral family that includes major pathogens of humans and other mammals. (biomedcentral.com)
  • This relative independence of the viruses from the host cells is consistent with the fact that all these viruses encode several conserved proteins that mediate most of the processes essential for viral reproduction. (biomedcentral.com)
  • A major structural distinction that dictates the entry mode is the presence or absence of a lipid bilayer surrounding the viral nucleocapsid, which defines a virus as enveloped or nonenveloped, respectively. (scoop.it)
  • Pithovirus is an amazing virus that hints about the yet undiscovered viral diversity that awaits discovery. (wordpress.com)
  • The above story is reprinted from materials provided by Virology blog: About Viruses and Viral Disease . (wordpress.com)
  • A virus is genetic material contained within an organic particle that invades a living cell, using that cell's metabolism to produce new viral particles. (planetvirus.net)
  • Consistent with this large genome, Mimivirus particles have a size comparable to that of small bacteria such as U. urealyticum ( Fig. 1 B). The viruses with the largest genomes previously described are a Phycodnavirus infecting Pyramimonas algae (560 kbp) and phage D of Bacillus megaterium (670 kbp) ( 4 , 5 ). (sciencemag.org)
  • They have extremely large genomes compared to other viruses and contain many unique genes not found in life forms. (wikipedia.org)
  • The viruses' large, double-stranded DNA genomes (300 to 1000 kilobasepairs or larger) encode a large contingent of genes (of the order of 1000 genes). (wikipedia.org)
  • The genomes of giant viruses are the largest known for viruses, and contain genes that encode for important elements of translation machinery, a characteristic that had previously been believed to be indicative of cellular organisms. (wikipedia.org)
  • The presence of four aminoacyl tRNA synthetase encoding genes in mimivirus and mamavirus genomes, both species within the Mimiviridae family, as well as the discovery of seven aminoacyl tRNA synthetase genes, including the four genes present in Mimiviridae, in the megavirus genome provide evidence for a possible scenario in which these large DNA viruses evolved from a shared ancestral cellular genome by means of genome reduction. (wikipedia.org)
  • While the exact criteria as defined in the scientific literature vary, giant viruses are generally described as viruses having large pseudo-icosahedral capsids (200 to 400 nanometers) which can be surrounded by a thick (approximately 100 nm) layer of filamentous protein fibers with large double-stranded DNA genomes (300 to 1000 kilobase pairs or larger) encoding a large contingent of genes (of the order of 1000 genes). (wikipedia.org)
  • Table 1 : Largest giant viruses with complete sequenced genomes The whole list is in the Giant Virus Toplist created by the Giant Virus Finder software. (wikipedia.org)
  • The family Asfarviridae includes the single species African swine fever virus , isolates of which have linear dsDNA genomes of 170-194 kbp (Table 1. (ictvonline.org)
  • There are other viruses with genomes of this size packed into much smaller particles - so why is the Pithovirus particle so large? (wordpress.com)
  • These families all contain large icosahedral viruses with DNA genomes. (wordpress.com)
  • Sputnik" is a dsDNA virus, referred to as a virophage, that is coassembled with Mimivirus in the host amoeba. (pnas.org)
  • Sputnik virus was discovered to be associated with Mimivirus when isolated from amoeba ( 2 ). (pnas.org)
  • The amoeba host implies that both Mimivirus and Sputnik are frequently present in aquatic food, resulting in disease when humans eat raw food ( 3 ). (pnas.org)
  • This amoeba had been previously used to propagate other giant viruses, such as Mimivirus and Pandoravirus. (wordpress.com)
  • A ) Mimivirus (arrows) in cytocentrifuged A. polyphaga as Gram-positive particles. (sciencemag.org)
  • As it resembles a bacterium on Gram staining, it was named Mimivirus (for Mimicking microbe) ( Fig. 1 A). DNA digestion by Sal I and Sac II treatment of purified particles ( 2 ), followed by pulsed-field gel electrophoresis, demonstrated that Mimivirus has a double-stranded DNA circular genome of about 800 kilobase pairs (kbp). (sciencemag.org)
  • In animal cells, virus particles are gathered by the microtubule-dependent aggregation of toxic or misfolded protein near the microtubule organizing center (MTOC), so the viroplasms of animal viruses are generally localized near the MTOC. (wikipedia.org)
  • The discovery of Mimivirus in 2002 ( 1 ) broke with the long-held assumption that viruses are small particles that can be isolated from samples by filtering through small pore sizes. (pnas.org)
  • The term virus was later used to describe such fluids, also called " filterable agents ", which were thought to contain no particles. (rybicki.blog)
  • however, what happens is that virus particles fuse with the target cells, and deliver their genetic material plus inside . (rybicki.blog)
  • African swine fever virus (ASFV) is a large, double-stranded DNA virus in the Asfarviridae family. (wikipedia.org)
  • ASFV is endemic to sub-Saharan Africa and exists in the wild through a cycle of infection between ticks and wild pigs, bushpigs, and warthogs. (wikipedia.org)
  • ASFV is a large, icosahedral, double-stranded DNA virus with a linear genome of 189 kilobases containing more than 180 genes. (wikipedia.org)
  • All ASFV p72 genotypes have been circulating in eastern and southern Africa. (wikipedia.org)
  • African swine fever virus (ASFV) virions consist of a nucleoprotein core structure, 70-100 nm in diameter, surrounded by an internal lipid layer and an icosahedral capsid, 170-190 nm in diameter, which in turn is eventually surrounded by an external lipid-containing envelope. (ictvonline.org)
  • The virus encodes enzymes required for replication and transcription of its genome, including elements of a base excision repair system, structural proteins, and many proteins that are not essential for replication in cells, but instead have roles in virus survival and transmission in its hosts. (wikipedia.org)
  • The virus encodes proteins that inhibit signalling pathways in infected macrophages and thus modulate transcriptional activation of immune response genes. (wikipedia.org)
  • In addition, the virus encodes proteins which inhibit apoptosis of infected cells to facilitate production of progeny virions. (wikipedia.org)
  • The viroplasm is where components such as replicase enzymes, virus genetic material, and host proteins required for replication concentrate, and thereby increase the efficiency of replication. (wikipedia.org)
  • Disruption of cellular membranes can, for example, slow the transport of immunomodulatory proteins to the surface of infected cells and protect against innate and acquired immune responses, and rearrangements to cytoskeleton can facilitate virus release. (wikipedia.org)
  • It is possible that a cellular response originally designed to reduce the toxicity of misfolded proteins is exploited by cytoplasmic viruses to improve their replication, the virus capsid synthesis, and assembly. (wikipedia.org)
  • We have used cryo-EM to produce an electron density map of the icosahedral Sputnik virus at 3.5-Å resolution, sufficient to verify the identity of most amino acids in the capsid proteins and to establish the identity of the pentameric protein forming the fivefold vertices. (pnas.org)
  • Table 2: Specific common features among giant viruses 1Mutator S (MutS) and its homologs are a family of DNA mismatch repair proteins involved in the mismatch repair system that acts to correct point mutations or small insertion/deletion loops produced during DNA replication, increasing the fidelity of replication. (wikipedia.org)
  • Nevertheless, large groups of viruses infecting diverse hosts do appear to be monophyletic as indicated by the conservation of sets of genes encoding proteins responsible for most of the functions essential for virus reproduction. (biomedcentral.com)
  • Vincent, Dick, and Alan talk about insect and human dengue virus host proteins, equine vaccine for WNV and EEEV, return of swine flu to humans, spread of polio in Africa, and listener email. (microbe.tv)
  • Dixon, L. K., Immunisation of pigs by DNA prime and recombinant vaccinia virus boost to identify and rank African swine fever virus immunogenic and protective proteins. (asu.edu)
  • Only 32% of the 467 predicted Pithovirus proteins have homologs in protein databases (this number was 61% for Mimivirus and 16% for Pandoravirus). (wordpress.com)
  • Iridoviridae and Phycodnaviridae are aquatic viruses, and Asfarviridae infect vertebrates ( 6 ). (sciencemag.org)
  • Here we describe the structure of faustovirus, the prototypic member of a new family of large double-stranded DNA viruses that are homologs of the Asfarviridae . (pnas.org)
  • The virus has a double-stranded DNA (dsDNA) genome of 466,000 base pairs that encodes 451 predicted ORFs, about two-thirds of which do not have any known homologs. (pnas.org)
  • Mysterious Microbe in Water Challenges the Very Definition of a Virus" (PDF). (wikipedia.org)
  • Mimivirus is a nucleocytoplasmic large DNA virus (NCLDV). (sciencemag.org)
  • Viruses portal Nucleocytoplasmic large DNA viruses Pithovirus Pandoravirus Klosneuvirus Mimivirus Cafeteria roenbergensis virus Reynolds KA (2010). (wikipedia.org)
  • The virus spread from West Africa to the Iberian peninsula, remaining endemic for 30 years, and was finally eradicated from Europe except for the island of Sardinia, Italy. (ictvonline.org)
  • HIV-2, which is prevalent in West Africa and has spread to Europe and India, is almost indistinguishable from an SIV that infects sooty mangabey monkeys. (rybicki.blog)
  • Sequences homologous to the major capsid protein (MCP) of Sputnik have been found in Mavirus (19% sequence identity) and Organic Lake virus (28% sequence identity). (pnas.org)
  • A 10.7-Å resolution cryo-EM study of the Sputnik virus ( 9 ) had shown that the capsid protein assembled into an icosahedral shell with a diameter of approximately 750 Å and T = 27 quasi-symmetry ( SI Materials and Methods ). (pnas.org)
  • While few giant viruses have been characterized in detail, the most notable examples are the phylogenetically related mimivirus and megavirus - both belonging to the Mimiviridae (aka Megaviridae) family, due to their having the largest capsid diameters of all known viruses. (wikipedia.org)
  • The crystal structure of the major capsid protein, in combination with cryo-electron microscopy structures of two different maturation stages of the virus, shows that the outer virus shell is composed of a double jelly-roll protein that can be found in many double-stranded DNA viruses. (pnas.org)
  • a) Diagram of extracellular African swine fever virus virions showing nucleoid, inner core shell, internal membrane, capsid and outer envelope. (ictvonline.org)
  • Black arrow shows capsid protein, white arrow shows virus membrane. (ictvonline.org)
  • While some of these viruses have potential medical applications - the methods CroV uses to assemble its protein shell, or capsid, are similar to those used by influenza viruses - many more play a quiet role in bringing balance to aquatic ecosystems. (asbmb.org)
  • This group of viruses includes four other families, including the enveloped Poxviridae , which infect vertebrates ( Chordopoxvirinae ) and insects ( Entomopoxvirinae ). (sciencemag.org)
  • The majority of replication and assembly occurs in discrete, perinuclear regions of the cell called virus factories, and finally progeny virions are transported to the plasma membrane along microtubules where they bud out or are propelled away along actin projections to infect new cells. (wikipedia.org)
  • The Nucleo-Cytoplasmic Large DNA Viruses (NCLDV) comprise an apparently monophyletic class of viruses that infect a broad variety of eukaryotic hosts. (biomedcentral.com)
  • Given the astonishing diversity of viruses that infect mammals alone-hundreds of thousands of different viruses according to some estimates [2]-it is unsurprising that their entry routes into cells are just as diverse. (scoop.it)
  • Vincent, Dick, Alan, and Hamish Young focus on the new H1N1 influenza virus, which originated in swine and is likely to be the next pandemic strain. (microbe.tv)
  • ABSTRACT Rio Negro virophage (RNV) was co-isolated with a strain of mimivirus named sambavirus, from Brazilian Amazon. (bvsalud.org)
  • The virus is thought to be derived from a virus of soft tick (genus Ornithodoros) that infects wild swine, including giant forest hogs (Hylochoerus meinertzhageni), warthogs (Phacochoerus africanus), and bushpigs (Potamochoerus porcus). (wikipedia.org)
  • These viruses are the first members of the proposed "Pandoravirus" genus, a term reflecting their lack of similarity with previously described microorganisms and the surprises expected from their future study. (nih.gov)
  • According to the VIIIth Report of the International Committee on Taxonomy of Viruses (ICTV) [ 20 ], the dsDNA viruses can be classified into certain families or unassigned genus. (biomedcentral.com)
  • Genus Tequatrovirus ( T4virus , T4-ähnliche Viren , en. (wikipedia.org)
  • The name therefore refers both to the morphology of the virus particle and its similarity to Pandoravirus. (wordpress.com)
  • We now know of viruses from two different families that have similar morphology: an amphora-like shape, an apex, and a thick electron-dense tegument covered by a lipid membrane enclosing an internal compartment. (wordpress.com)
  • Vincent, Alan, and Stephen Morse discuss progressive vaccinia in a smallpox vaccinee, arsenic and influenza in mice, facemasks and flu transmission, and antigenic and genetic analyses of the new H1N1 influenza virus. (microbe.tv)
  • On this special episode of TWiV, Vincent and Dr. Peter Palese, noted influenza expert, discuss the origin and pandemic potential of the new H1N1 influenza virus. (microbe.tv)
  • The rapid transmission of the pandemic 2009 H1N1 influenza virus (pH1N1) among humans has raised the concern of a potential emergence of reassortment between pH1N1 and highly pathogenic influenza strains, especially the avian H5N1 influenza. (scoop.it)
  • Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. (nature.com)
  • es el caso del virus chikungunya, un arbovirus reemergente que ha activado las alarmas mundiales. (bvsalud.org)
  • En esta revisión se incluyen los siguientes aspectos de la infección por el virus chikungunya: virología, transmisión por vector, patogenia, epidemiología, manifestaciones clínicas,pruebas de laboratorio, medidas de prevención y perspectivas futuras. (bvsalud.org)
  • Such is the case of chikungunya virus (CHIKV), a re-emerging arbovirus that has triggered global alarm. (bvsalud.org)
  • While the exact criteria as defined in the scientific literature vary, giant viruses are generally described as viruses having large, pseudo-icosahedral capsids (200 to 400 nanometers) that may be surrounded by a thick (approximately 100 nm) layer of filamentous protein fibers. (wikipedia.org)
  • Contrary to other large viruses, faustovirus has a double-protein shell surrounding the genomic material, something never described before for a DNA virus. (pnas.org)
  • Many viruses protect their genome with a combination of a protein shell with or without a membrane layer. (pnas.org)
  • Here we describe the structure of faustovirus, the first DNA virus (to our knowledge) that has been found to use two protein shells to encapsidate and protect its genome. (pnas.org)
  • At the University of Texas at El Paso, Chuan Xiao, who also goes by River, makes use of a 10-foot transmission electron microscope to puzzle out how Cafeteria roenbergensis virus assembles its protein shell. (asbmb.org)
  • Xiao recently received a $1.75 million grant from the National Institutes of Health to continue characterizing the processes by which a giant virus, cafeteria roenbergensis virus, or CroV, assembles its protein shell. (asbmb.org)
  • The virus infects its target cells - which happen to mainly be helper T-lymphocytes - by specifically attaching to a protein carried on the surface of the cells known as CD4. (rybicki.blog)
  • In contrast to other giant DNA viruses, the genome of Pithovirus does not encode any component of the protein synthesis machinery. (wordpress.com)
  • Vincent, Alan, and Raul Rabadan converse about polio survivors in iron lungs, bocavirus, structure of mimivirus, and genome sequence analysis of influenza H1N1 viruses. (microbe.tv)
  • Despite the physical similarity with Pandoravirus, the Pithovirus genome sequence reveals that it is barely related to that virus, but more closely resembles members of the Marseillviridae , Megaviridae , and Iridoviridae . (wordpress.com)
  • IMPORTANCE By using Vermamoeba , a protist living in humans and their environment, we isolated eight strains of a new giant virus that we named faustovirus. (asm.org)
  • While people were aware of diseases of both humans and animals now known to be caused by viruses many hundreds of years ago, the concept of a virus as a distinct entity dates back only to the very late 1800s. (rybicki.blog)
  • Influenza and the new Nipah virus in South-East Asia reached humans via pigs. (rybicki.blog)
  • Viroplasms have been reported in many unrelated groups of Eukaryotic viruses that replicate in cytoplasm, however, viroplasms from plant viruses have not been as studied as viroplasms from animal viruses. (wikipedia.org)
  • Giant viruses replicate within large spheroidal virus factories located within the cytoplasm of the infected host cell. (wikipedia.org)
  • Although Group VII viruses such as hepatitis B contain a DNA genome, they are not considered DNA viruses according to the Baltimore classification, but rather reverse transcribing viruses because they replicate through an RNA intermediate. (wikidoc.org)
  • Introduction: Viruses deploy diverse entry strategies All viruses must enter cells to replicate [1]. (scoop.it)
  • Our results suggest that marine NCLDVs probably outnumber eukaryotic organisms in the photic layer (per given water mass) and that metagenomic sequence analyses promise to shed new light on the biodiversity of marine viruses and their interactions with potential hosts. (nature.com)
  • Since the discovery of the giant Mimivirus from fresh water samples, NCLDVs have become a subject of broader interest. (nature.com)
  • The diversity of these giant viruses (the Megaviridae) was assessed by sampling a variety of aquatic environments and their associated sediments worldwide. (nih.gov)
  • Our taxon co-occurrence analysis revealed a potential association between viruses of the Megaviridae family and eukaryotes related to oomycetes. (nature.com)
  • Xiao's analysis of CroV is made possible by a 14-foot-tall electron microscope housed in an interference-minimizing room - a dedicated piece of equipment that, while not rare, carried a $1.8 million price tag for the department and demands intense computing power to render images of viruses that are more than three times larger than HIV or influenza virions. (asbmb.org)
  • Virus replication takes place in perinuclear factory areas. (wikipedia.org)
  • The recruitment of cellular membranes and cytoskeleton to generate virus replication sites can also benefit viruses in other ways. (wikipedia.org)
  • Cellular membranes ensure functional compartmentalization by dynamic fusion-fission remodeling and are often targeted by viruses during entry, replication, assembly, and egress. (asm.org)
  • This is similar to the replication mechanism used by Poxviridae, though whether this mechanism is employed by all giant viruses or only mimivirus and the related mamavirus has yet to be determined. (wikipedia.org)
  • These virion replication factories can themselves be infected by the virophage satellite viruses, which inhibit or impair the reproduction of the complementary virus. (wikipedia.org)
  • These virion replication factories are themselves subject to infection by the virophage satellite viruses, which inhibit or impair the reproductive capabilities of the complementary virus. (wikipedia.org)
  • This reconstructed ancestral gene set is robust to the parameters of the reconstruction procedure and so is likely to accurately reflect the gene core of the ancestral NCLDV, indicating that this virus encoded a complex machinery of replication, expression and morphogenesis that made it relatively independent from host cell functions. (biomedcentral.com)
  • Pithovirus therefore undergoes its entire replication cycle in the cytoplasm, much like other large DNA viruses such as poxviruses. (wordpress.com)
  • Faustovirus shows distant homology to African swine fever virus but probably constitutes its own family within the growing proposed order of Megavirales . (pnas.org)
  • HIV-1, the retrovirus that is responsible for the AIDS pandemic, is closely related to a simian immunodeficiency virus (SIV) which infects chimpanzees. (rybicki.blog)
  • Viroplasms have been found in the cauliflower mosaic virus, rotavirus, vaccinia virus and the rice dwarf virus. (wikipedia.org)
  • ICTVdb Index of Viruses: Virus Taxonomy, 8th Reports of the International Committee on Taxonomy of Viruses: Listing in Taxonomic Order. (wikipedia.org)
  • The trees from our analyses are in good agreement to the latest classification of large dsDNA viruses and parvoviruses by the International Committee on Taxonomy of Viruses (ICTV). (biomedcentral.com)
  • The International Committee on the Taxonomy of Viruses (ICTV) publishes a report on the virus taxonomy system every five years. (biomedcentral.com)
  • Die Entscheidung über verschiedene Taxa wird von einem internationalen Gremium, dem International Committee on Taxonomy of Viruses (ICTV), beraten und getroffen. (wikipedia.org)
  • Their discovery and subsequent characterization has triggered some debate concerning the evolutionary origins of giant viruses. (wikipedia.org)
  • The discovery and subsequent characterization of these giant viruses has triggered some debate concerning the evolutionary origins of the giruses, going so far as to suggest that the giruses provide evidence of a fourth domain of life. (wikipedia.org)
  • Evolutionary reconstructions employing NCVOGs point to complex ancestral viruses. (biomedcentral.com)
  • Viruses as a concept are just a little younger than bacteria - they were first described only in the 1890s - yet have probably co-existed with cellular life through nearly the whole of evolutionary history on this planet. (rybicki.blog)
  • On the other hand, the genome sizes of ssDNA viruses are smaller than 10 kb. (biomedcentral.com)
  • Yutin and Koonin, 2012 ) constitute an apparently monophyletic group of eukaryotic viruses with a large double-stranded DNA (dsDNA) genome ranging from 100 kb up to 1.26 Mb. (nature.com)
  • A maximum-likelihood reconstruction of the NCLDV evolution yielded a set of 47 conserved genes that were probably present in the genome of the common ancestor of this class of eukaryotic viruses. (biomedcentral.com)
  • The origin of these P450 genes in giant viruses remains unknown but may have been acquired from an ancient host. (wikipedia.org)
  • These results suggest a mechanism of Sputnik DNA ejection that probably also occurs in other big icosahedral double jelly-roll viruses such as Adenovirus. (pnas.org)
  • However, no gene is common to all viruses, so there is no evidence of a monophyletic origin of all viruses, at least, not within the traditional concept of monophyly. (biomedcentral.com)
  • The phylogeny based on single genes or gene families contains ambiguity because horizontal gene transfer (HGT), along with gene duplication and gene capture from hosts, appear to be frequent in large DNA viruses [ 7 - 10 ]. (biomedcentral.com)
  • The two main hypotheses for their origin are that either they evolved from small viruses, picking up DNA from host organisms, or that they evolved from very complicated organisms into the current form which is not self-sufficient for reproduction. (wikipedia.org)
  • However, little is known about the diversity, abundance and biogeography of marine viruses infecting other cellular organisms, in particular eukaryotes. (nature.com)
  • Viruses are the most abundant and, arguably, one of the most important organisms on Earth. (planetvirus.net)
  • And while bacteria are living organisms, viruses are molecular parasites. (planetvirus.net)
  • It is the oldest DNA virus of eukaryotes ever isolated, showing that viruses can retain infectivity in nature for very long periods of time. (wordpress.com)
  • The number and the size of viroplasms depend on the virus, the virus isolate, hosts species, and the stage of the infection. (wikipedia.org)
  • This complexity might help the virus to rapidly adapt to new environments or hosts. (pnas.org)
  • Although larger viruses had been described before, the combination of less stringent selection criteria with new hosts enabled the discovery of a broad range of large viruses that had previously been ignored. (pnas.org)
  • Amoebae have been shown to be versatile hosts for the isolation of new viruses from environmental samples. (pnas.org)
  • Readers learn about the history of this unique science, how viruses are named, how their genes work, how they copy and package themselves, how they interact with their hosts, how immune systems counteract viruses, and how viruses travel from host to host. (credoreference.com)
  • Herpes viruses are double stranded DNA viruses assigned to Group I . The Herpesviridae Study Group has proposed that herpes viruses be assigned to a newly defined order, Herpesvirales. (wikidoc.org)
  • Other virophages such as Mavirus and Organic Lake virus, which are associated with giant dsDNA viruses, have been discovered recently ( 7 , 8 ). (pnas.org)
  • These findings show that expanding the panel of protists to discover new giant viruses is a fruitful strategy. (asm.org)
  • A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. (wikipedia.org)
  • All known giant viruses belong to the phylum Nucleocytoviricota. (wikipedia.org)
  • What sort of complicated organism giant viruses might have diverged from is also a topic of debate. (wikipedia.org)
  • The whole list is in the Giant Virus Toplist created by the Giant Virus Finder software. (wikipedia.org)
  • Since the discovery of Mimivirus in 2003, many new giant viruses have been isolated and characterized, now that the definition of viruses excludes their ability to pass through the finest available filters. (pnas.org)
  • A giant virus is a very large virus, some of which are larger than typical bacteria. (wikipedia.org)
  • We report the isolation of two giant viruses, one off the coast of central Chile, the other from a freshwater pond near Melbourne (Australia), without morphological or genomic resemblance to any previously defined virus families. (nih.gov)
  • If the words "giant viruses" strike fear - or nihilistic delight - you need not worry. (asbmb.org)
  • B ) Electronic microscopy of Mimivirus and U. urealyticum . (sciencemag.org)
  • The question is how many viruses are built with the pithovirus/pandoravirus structure. (wordpress.com)
  • The requirement of Mimivirus for the propagation of Sputnik gave rise to the term "virophage" ( 4 ). (pnas.org)
  • The virus factory is often enclosed by a membrane derived from the rough endoplasmic reticulum or by cytoskeletal elements. (wikipedia.org)
  • It was also shown that the virus lacks an internal membrane. (pnas.org)
  • For Xiao, the paper marked the beginning of a nearly three-year struggle to reconstruct the virus' membrane, which is dotted with asymmetrical, rodlike fibers. (asbmb.org)
  • One end of the virus particle appears to be sealed with what the authors call a cork (photo). (wordpress.com)
  • This feature, along with the shape of the virus particle, inspired the authors to name the new isolate Pithovirus, from the Greek word pithos which refers to the amphora given to Pandora. (wordpress.com)
  • Since the discovery of Mimivirus, the founding member of the family Mimiviridae, three lineages, A-C, have been delineated among the mimiviruses of amoebae. (nih.gov)
  • Using previously developed computational methods for orthology identification, 1445 Nucleo-Cytoplasmic Virus Orthologous Groups (NCVOGs) were identified of which 177 are represented in more than one NCLDV family. (biomedcentral.com)
  • A typical virus developmental cycle, including an eclipse phase, was observed (fig. S2). (sciencemag.org)
  • Plant viruses induce the rearrangement of membranes structures to form the viroplasm. (wikipedia.org)
  • The virus is endemic in Africa where warthogs and bush pigs act as reservoirs. (ictvonline.org)
  • Sir Arnold Theiler , a Swiss-born veterinarian working in South Africa, had developed a crude vaccine against rinderpest by 1897 , without knowledge of the nature of the agent: this consisted of blood from an infected animal, injected with serum from one that had recovered. (rybicki.blog)
  • Here, we report that the cold-adapted pH1N1 live attenuated vaccine (CApH1N1) elicits cross-reactive immunity against seasonal and H5 influenza A viruses in the mouse model. (scoop.it)
  • Our results not only accentuate the merit of using live attenuated influenza vaccines in view of cross-reactivity, but also represent the potential of CApH1N1 live vaccine for mitigating the clinical severity that arises from reassortant viruses between pH1N1 and highly pathogenic H5 subtype viruses. (scoop.it)
  • G Sanarelli , working in Uruguay, described the smallpox virus relative and tumour-causing myxoma virus of rabbits as a virus. (rybicki.blog)
  • A finding that was later to have great importance in veterinary virology was the discovery by Maurice Nicolle and Adil Mustafa in Turkey in 1902 , that rinderpest or cattle plague was caused by a virus. (rybicki.blog)